aztreonam has been researched along with ceftazidime in 164 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (0.61) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 112 (68.29) | 29.6817 |
| 2010's | 48 (29.27) | 24.3611 |
| 2020's | 3 (1.83) | 2.80 |
| Authors | Studies |
|---|---|
| Indelicato, JM; Pasini, CE | 1 |
| Cheng, ML; Duffield, J; Hu, C; Hwang, SB; Ichikawa, Y; Liang, CH; Marby, KA; Rabuka, D; Romero, A; Sears, P; Sgarbi, PW; Shue, YK; Sucheck, SJ; Yao, S | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Cattoir, V; Nordmann, P; Poirel, L; Soares, A; Soussy, CJ | 1 |
| Chen, YG; Du, XX; Li, LJ; Shen, P; Wei, ZQ; Yu, YS | 1 |
| Alba, L; Chen, Y; Garber, E; Saiman, L; Tabibi, S; Zhou, J | 1 |
| Adams, J; de Oliveira Garcia, D; Doi, Y; Paterson, DL | 1 |
| Cornaglia, G; Koncan, R; Mazzariol, A; Roelofsen, E; Voss, A | 1 |
| Bonnet, R; Chanal, C; Delmas, J; Lesens, O; Robin, F; Schweitzer, C; Tournilhac, O | 1 |
| Ko, WC; Tsai, SH; Wu, JJ; Yan, JJ | 1 |
| Aubert, D; Naas, T; Nordmann, P; Ozcan, A | 1 |
| Dumas, JL; Köhler, T; Reinhardt, A; Ricou, B; Rohner, P; van Delden, C; Wood, P | 1 |
| Correa, A; Kattan, JN; Lolans, K; Lopez, JA; Quinn, JP; Villegas, MV | 1 |
| Arlet, G; Loli, A; Miriagou, V; Papagiannitsis, CC; Tzelepi, E; Tzouvelekis, LS | 1 |
| Caniça, M; Ferreira, E; Leitão, J; Manageiro, V; Mendonça, N | 1 |
| Cauda, R; Citton, R; D'Inzeo, T; Fadda, G; Fiori, B; Montuori, E; Posteraro, B; Sanguinetti, M; Spanu, T; Trecarichi, EM; Tumbarello, M | 1 |
| Bonomo, RA; Endimiani, A; Hujer, AM; Hujer, KM; Luzzaro, F; Mantengoli, E; Migliavacca, R; Pagani, L; Rossolini, GM; Toniolo, A | 1 |
| Ariza, J; Dominguez, MA; Gudiol, F; Guzmán, A; Peña, C; Pujol, M; Suarez, C; Tubau, F | 1 |
| Cattoir, V; Corvec, S; Drugeon, H; Faccone, D; Galas, M; Mugnier, P; Nordmann, P; Pasteran, F; Petroni, A; Poirel, L; Rapoport, M | 1 |
| Ayala, JA; Casellas, JM; Di Conza, J; Ghiglione, B; Gutkind, G; Power, P; Radice, M; Rodríguez, MM | 1 |
| Kamat, V; Sekar, U; Toleman, MA; Vinodh, H; Walsh, TR | 1 |
| Avlami, A; Daikos, GL; Katsilambros, N; Kosmidis, C; Petrikkos, G; Psychogiou, M; Stefanou, I; Tassios, PT; Vasilakopoulou, A | 1 |
| Bille, J; Lartigue, MF; Nordmann, P; Poirel, L; Wenger, A; Zinsius, C | 1 |
| Amicosante, G; Caporale, B; Celenza, G; Docquier, JD; Mezzatesta, M; Pellegrini, C; Perilli, M; Rossolini, GM; Stefani, S | 1 |
| Borrell, N; Maciá, MD; Moya, B; Oliver, A; Pérez, JL; Plasencia, V | 1 |
| Andrew, T; Bush, K; Davies, TA; Kania, M; Page, MG; Shang, W | 1 |
| Castanheira, M; Jones, RN; Mendes, RE; Sader, HS; Toleman, MA; Walsh, TR | 1 |
| Afkou, Z; Ikonomidis, A; Labrou, M; Maniatis, AN; Pournaras, S; Sofianou, D; Tsakris, A | 1 |
| Bae, IK; Jeong, SH; Lee, SH; Lee, WG; Lee, YN | 1 |
| Chen, YT; Lauderdale, TL; Liao, TL; Shiau, YR; Shu, HY; Su, IJ; Tsai, SF; Wu, KM; Yan, JJ | 1 |
| Carmeli, Y; Chmelnitsky, I; Leavitt, A; Navon-Venezia, S; Schwaber, MJ | 1 |
| Hovde, LB; Kroeger, LA; Mitropoulos, IF; Rotschafer, JC; Schafer, J | 1 |
| Grosso, F; Peixe, L; Quinteira, S; Ramos, H | 1 |
| Beceiro, A; Bou, G; Canle, D; Fernández, A; Lasa, I; Latasa, C; Mallo, S; Molina, F; Pérez, A; Pérez, S; Poza, M; Tomás, Mdel M; Villanueva, R | 1 |
| Miriagou, V; Papagiannitsis, CC; Tzelepi, E; Tzouvelekis, LS | 1 |
| Bajolet, O; Berthelot, P; Bingen, E; Couetdic, G; Favre, R; Grattard, F; Hocquet, D; Husson, MO; Jeannot, K; Mariani-Kurkdjian, P; Marty, N; Plésiat, P; Roussel-Delvallez, M | 1 |
| Bonnet, R; Brebion, A; Constantin, JM; Delmas, J; Dubois, D; Robin, F | 1 |
| Fung, CP; Hsieh, YP; Hu, WS; Lin, JF; Liu, CP; Yao, SM | 1 |
| Girlich, D; Leclercq, R; Naas, T; Nordmann, P | 1 |
| Correia, A; Domingues, MR; Domingues, P; Fonseca, F; Henriques, I; Saavedra, MJ; Samyn, B; Sarmento, AC; van Beeumen, J | 1 |
| Bonnet, R; Neuwirth, C; Robin, F; Siebor, E | 1 |
| Bouza, E; Cercenado, E; Coll, P; Gutiérrez, O; Juan, C; Navarro, F; Oliver, A; Pérez, JL | 1 |
| Iredell, JR; Partridge, SR; Zong, Z | 1 |
| Cuzon, G; Demachy, MC; Naas, T; Nordmann, P | 1 |
| Courvalin, P; Decré, D; Høiby, EA; Meziane-Cherif, D; Périchon, B | 1 |
| Amicosante, G; Celenza, G; De Santis, F; Forcella, C; Pellegrini, C; Perilli, M; Rossolini, GM; Stefani, S | 1 |
| Courvalin, P; Dupêchez, M; Galimand, M; Lambert, T; Meziane-Cherif, D | 1 |
| Cuzon, G; Lartigue, MF; Naas, T; Nordmann, P; Quinn, JP; Villegas, MV | 1 |
| Bush, K; Davies, TA; Flamm, RK; Shang, W | 1 |
| Gianneli, D; Loli, A; Miriagou, V; Tzelepi, E; Tzouvelekis, LS | 1 |
| Bouallegue, O; Mansour, W; Nordmann, P; Poirel, L | 1 |
| Bonnet, R; Caniça, M; Ferreira, E; Manageiro, V; Mendonça, N; Robin, F; Salgado, MJ | 1 |
| Bonnet, R; Caniça, M; Manageiro, V; Mendonça, N | 1 |
| Cai, JC; Chen, GX; Zhang, R; Zhou, HW | 1 |
| Adams-Haduch, JM; de Oliveira Garcia, D; Doi, Y; Freire, MP; Leite, D; Padoveze, MC; Paterson, DL; Silveira, FP; Szabo, D; Vaz, TM | 1 |
| Limansky, AS; Marchiaro, P; Mussi, MA; Pasteran, F; Tomatis, PE; Viale, AM; Vila, AJ | 1 |
| Doi, Y; Nordmann, P; Paterson, DL; Poirel, L | 1 |
| Bethel, CR; Bonomo, RA; Carias, LL; Endimiani, A; Fox, WR; Hall, GS; Hujer, AM; Hujer, KM; Hutton, RA; Jacobs, MR; Jenkins, SG; Paterson, DL; Perez, F; Rice, LB; Tenover, FC | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chen, TL; Cho, WL; Fung, CP; Shaio, MF; Wu, RC | 1 |
| Docquier, JD; Frère, JM; Rossolini, GM; Stoczko, M | 1 |
| Carrillo, B; Esparza-Ahumada, S; Garza-Ramos, U; Hernández, E; Jones, RN; Morfin-Otero, R; Rodriguez-Noriega, E; Sader, HS; Sanchez, A; Silva-Sanchez, J | 1 |
| Badur, S; Cagatay, AA; Carrër, A; Eraksoy, H; Nordmann, P; Poirel, L | 1 |
| Carmeli, Y; Chmelnitsky, I; Navon-Venezia, S; Strahilevitz, J | 1 |
| Bauernfeind, A; Keuleyan, E; Markovska, R; Queenan, AM; Rasshofer, R; Schneider, I | 1 |
| Castanheira, M; Samuelsen, Ø; Spencer, J; Walsh, TR | 1 |
| Bratu, S; Georgescu, C; Landman, D; Martin, DA; Quale, J | 1 |
| Jarlier, V; Mayer, C; Petrella, S; Renard, M; Sougakoff, W; Ziental-Gelus, N | 1 |
| Albertí, S; Beceiro, A; Bou, G; Garau, M; Gutiérrez, O; Juan, C; Oliver, A; Pérez, JL | 1 |
| Cattoir, V; Nordmann, P; Poirel, L | 1 |
| Bogaerts, P; Cuzon, G; Glupczynski, Y; Huang, TD; Naas, T; Nordmann, P | 1 |
| Arpin, C; Bezian, MC; Coulange, L; Demarthe, F; Dubois, V; Minarini, LA; Nordmann, P; Poirel, L; Quentin, C | 1 |
| Hanaki, H; Maseda, H; Nakae, T; Sugimura, M | 1 |
| Kanamori, M; Kirikae, T; Kitao, T; Miyoshi-Akiyama, T; Morita, K; Okazaki, M; Sekiguchi, J; Watanabe, N | 1 |
| Hanson, ND; Schmidtke, AJ | 1 |
| Amicosante, G; De Luca, F; Luzzaro, F; Migliavacca, R; Mugnaioli, C; Pagani, L; Perilli, M; Pini, B; Pollini, S; Rossolini, GM; Spalla, M; Toniolo, A | 1 |
| Arakawa, Y; Ishikawa, K; Nagano, N; Nagano, Y; Wachino, J | 1 |
| Miriagou, V; Papagiannitsis, CC; Tzouvelekis, LS | 1 |
| Baptista, BC; Correia, JD; da Fonseca, JD; Martínez-Martínez, L; Pomba, C | 1 |
| Galleni, M; Mammeri, H; Nordmann, P | 1 |
| Bell, JM; Castanheira, M; Deshpande, LM; Jones, RN; Mendes, RE; Turnidge, JD | 1 |
| Asensi, MD; Gales, AC; Monteiro, J; Peirano, G; Santos, AF | 1 |
| Goering, RV; Hanson, ND; Kurpiel, PM; Palepou, MF; Wolter, DJ; Woodford, N | 1 |
| Beceiro, A; Bou, G; Cisneros, JM; Fernández-Cuenca, F; Martínez-Martínez, L; Pachón, J; Pascual, A; Pérez, A; Rodríguez-Baño, J; Vila, J | 1 |
| Bradford, PA; Jones, CH; Petersen, PJ; Ruzin, A; Tuckman, M; Visalli, MA | 1 |
| Nordmann, P; Plésiat, P; Poirel, L; Rodriguez-Martinez, JM | 1 |
| Kotsakis, SD; Miriagou, V; Tzelepi, E; Tzouvelekis, LS; Whichard, JM; Zioga, A | 1 |
| Bell, JM; Castanheira, M; Jones, RN; Mathai, D; Turnidge, JD | 1 |
| Juan, C; Maciá, MD; Mena, A; Mulet, X; Oliver, A; Pérez, JL | 1 |
| Duljasz, W; Gniadkowski, M; Jebelean, C; Sitter, S; Wojna, A | 1 |
| Della-Latta, P; Dib-Hajj, F; Dougherty, BA; Gootz, TD; He, W; Huard, RC; Lescoe, MK | 1 |
| Nordmann, P; Poirel, L; Rodríguez-Martínez, JM | 2 |
| Attrée, I; Ducruix, A; El Garch, F; Llanes, C; Muller, C; Phan, G; Plésiat, P; Vettoretti, L | 1 |
| Asgarali, A; Mark, BL; Oliver, A; Stubbs, KA; Vocadlo, DJ | 1 |
| Bonnet, R; Brisabois, A; Cloeckaert, A; Doublet, B; Fabre, L; Granier, SA; Robin, F; Weill, FX | 1 |
| Christiansen, LE; Ciofu, O; Høiby, N; Kirkby, N; Mandsberg, LF; Poulsen, HE | 1 |
| Kirikae, T; Kitao, T; Miyoshi-Akiyama, T | 1 |
| Bartolomé, R; Coelho, A; González-López, JJ; Larrosa, MN; Lavilla, S; Prats, G | 1 |
| Chanteperdrix, V; Croizé, J; Nordmann, P; Poirel, L; Potron, A | 1 |
| Adams-Haduch, JM; Bonomo, RA; Doi, Y; Endimiani, A; O'Keefe, A; Paterson, DL; Sidjabat, HE | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Brémont, S; Conroy, MC; Courvalin, P; Lambert, T; Moubareck, C | 1 |
| Kotsakis, SD; Miriagou, V; Papagiannitsis, CC; Tzelepi, E; Tzouvelekis, LS | 1 |
| Giakkoupi, P; Miriagou, V; Papagiannitsis, CC; Pappa, O; Polemis, M; Tzouvelekis, LS; Vatopoulos, AC; Zioga, A | 1 |
| Gales, AC; Nordmann, P; Picão, RC; Poirel, L | 1 |
| Bauernfeind, A; Keuleyan, E; Markova, B; Markovska, R; Queenan, AM; Schneider, I | 1 |
| De Luca, F; Delmarcelle, M; Docquier, JD; Dubus, A; Frère, JM; Nacoulma, OG; Rossolini, GM; Simporé, J; Zeba, B | 1 |
| Carattoli, A; Ellington, MJ; Karisik, E; Livermore, DM; Underwood, A; Woodford, N | 1 |
| Acosta, J; Chaves, F; Juan, C; Oliver, A; Otero, JR; Sanz, F; Viedma, E; Zamorano, L | 1 |
| Chung, DR; Ko, KS; Peck, KR; Son, JS; Song, JH; Suh, JY | 1 |
| Cho, HS; Giske, CG; Lee, K; Sundman, K; Toleman, MA; Walsh, TR; Yong, D | 1 |
| Albertí, S; Juan, C; Mulet, X; Oliver, A; Pérez, JL; Zamorano, L | 1 |
| Higgins, PG; Lehmann, M; Nordmann, P; Poirel, L; Seifert, H | 1 |
| Girlich, D; Nordmann, P; Poirel, L | 3 |
| Courvalin, P; Coyne, S; Guigon, G; Périchon, B | 1 |
| Bonnet, R; Casin, I; Doublet, B; Fabre, L; Le Fleche, A; Robin, F; Weill, FX | 1 |
| De Luca, F; Docquier, JD; Ide, L; Nordmann, P; Poirel, L; Rossolini, GM; Verlinde, A | 1 |
| Aggoune-Khinache, N; Bonnet, R; Delmas, J; Naim, M; Robin, F | 1 |
| Fortineau, N; Nordmann, P; Poirel, L; Rodriguez-Martinez, JM | 1 |
| Ge, Y; Juan, C; Oliver, A; Pérez, JL; Zamorano, L | 1 |
| Dunman, PM; Hood, MI; Jacobs, AC; Sayood, K; Skaar, EP | 1 |
| Kotsakis, SD; Legakis, NJ; Miriagou, V; Papagiannitsis, CC; Tzelepi, E; Tzouvelekis, LS | 1 |
| Akan, OA; Carrër, A; Cuzon, G; Feriha, C; Honderlick, P; Matar, G; Nordmann, P; Poirel, L; Yilmaz, M | 1 |
| Ge, Y; Juan, C; Moya, B; Oliver, A; Pérez, JL; Zamorano, L | 1 |
| De Luca, F; Docquier, JD; Fosse, T; Giraud-Morin, C; Rossolini, GM | 1 |
| Beceiro, A; Bou, G; Doumith, M; Livermore, DM; Tomás, M; Turton, JF; Warner, M; Woodford, N | 1 |
| Albuquerque, L; Bonnet, R; Caniça, M; Ferreira, E; Manageiro, V | 1 |
| Choi, JY; Ko, KS; Lee, MY; Park, YK; Peck, KR; Rhee, JY; Shin, JY; Song, JH | 1 |
| Carmeli, Y; Chmelnitsky, I; Goren, MG; Navon-Venezia, S | 1 |
| Dantier, C; Desarbre, E; Page, MG | 1 |
| Eb, F; Guillon, H; Mammeri, H | 1 |
| Al Naiemi, N; Debets-Ossenkopp, YJ; Nordmann, P; Poirel, L; Rodríguez-Martínez, JM | 1 |
| Carmeli, Y; Chmelnitsky, I; Goren, MG; Leavitt, A; Navon-Venezia, S; Ofek, I | 1 |
| Chang, FY; Chen, TL; Fung, CP; Huang, LY; Lu, PL; Siu, LK | 1 |
| Jo, S; Lee, IH; Lee, YH; Lee, YS; Park, HJ; Park, S; Shin, SH; Shin, YP | 1 |
| Galleni, M; Gutkind, G; Power, P; Rodríguez, MM; Sader, H | 1 |
| Abele-Horn, M; Claus, H; Elias, J; Engelhardt, K; Frosch, M; Joseph, B; Oesterlein, A; Schoen, C; Turnwald, D; Valenza, G | 1 |
| Bini, L; Bonomo, RA; Borgianni, L; Docquier, JD; Frère, JM; Matagne, A; Rossolini, GM; Vandenameele, J | 1 |
| Nordmann, P; Poirel, L; Rodríguez-Martínez, JM; Ronco, E | 1 |
| Bertrand, X; Dehecq, B; Hocquet, D; Mariotte, P; Plésiat, P; Talon, D | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Asai, Y; Fujii, N; Maekawa, K; Mizuno, H; Mori, K; Sakawaki, E; Sawamoto, K; Tanno, K; Uemura, S; Yokota, S | 1 |
| Cabot, G; Deng, L; Juan, C; Mark, BL; Moyá, B; Oliver, A; Reeve, TM; Vocadlo, DJ; Zamorano, L | 1 |
| Carattoli, A; García-Fernández, A; Giordano, A; Mancini, C; Miriagou, V; Papagiannitsis, CC; Venditti, M | 1 |
| Kotsakis, SD; Miriagou, V; Tzelepi, E; Tzouvelekis, LS | 1 |
| Bogaerts, P; Buvens, G; Glupczynski, Y; Lauwers, S; Piérard, D | 1 |
| Lagrutta, E; Nordmann, P; Pham, J; Poirel, L; Taylor, P | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Bae, IK; Jeong, SH; Kim, J; Lee, K; Suh, B; Yong, D | 1 |
| Borgianni, L; Docquier, JD; Hanson, ND; Prandi, S; Rossolini, GM; Salden, L; Santella, G | 1 |
| Ishii, Y; Matsuzawa, H; Mura, K; Oishi, M; Sakai, H; Shimizu-Ibuka, A; Yamada, S | 1 |
| Abramite, JA; Arcari, JT; Barham, RA; Brown, MF; Che, Y; Chen, JM; Chung, SW; Collantes, EM; Desbonnet, C; Doroski, M; Doty, J; Engtrakul, JJ; Harris, TM; Huband, M; Knafels, JD; Leach, KL; Liu, S; Marfat, A; Marra, A; McElroy, E; Melnick, M; Menard, CA; Montgomery, JI; Mullins, L; Noe, MC; O'Donnell, J; Oliver, R; Penzien, J; Plummer, MS; Price, LM; Reilly, U; Shanmugasundaram, V; Thoma, C; Uccello, DP; Warmus, JS; Wishka, DG | 1 |
| Anderson, KC; Kellogg, GE; Sarkar, A | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Bommareddy, A; Gionfriddo, MR; Heindel, GA; Mukhija, P; Vanwert, AL; Witkowski, S; Wolman, AT | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Bermingham, A; Blais, J; Capka, V; Cariaga, T; Casarez, A; Colvin, R; Dean, CR; Fekete, A; Gong, W; Growcott, E; Guo, H; Jones, AK; Li, C; Li, F; Lin, X; Lindvall, M; Lopez, S; McKenney, D; Metzger, L; Moser, HE; Prathapam, R; Rasper, D; Reck, F; Rudewicz, P; Sethuraman, V; Shaul, J; Shen, X; Simmons, RL; Tang, D; Tashiro, K; Tjandra, M; Turner, N; Uehara, T; Vitt, C; Whitebread, S; Yifru, A; Zang, X; Zhu, Q | 1 |
| Björkling, F; Bonke, G; Franzyk, H; Hansen, AM; Hogendorf, WFJ; Kongstad, KT; Nielsen, J; Nielsen, PE; Tomczak, M; Urbas, M; Zabicka, D | 1 |
| Bethel, CR; Bonomo, RA; Cmolik, A; Domitrovic, TN; Goldberg, JA; Hoyer, D; Hujer, AM; Hujer, KM; Jacobs, MR; Kreiswirth, BM; Kumar, V; Logan, LK; Marshall, EK; Marshall, SH; Nguyen, H; O'Shea, M; Papp-Wallace, KM; Perez, F; Plummer, MS; Rudin, SD; Spencer, EJ; van den Akker, F; van Duin, D | 1 |
| Bethel, CR; Bonomo, RA; Goldberg, JA; Hoyer, D; Hujer, AM; Hujer, KM; Jacobs, MR; Kreiswirth, BN; Kumar, V; Marshall, SH; Papp-Wallace, KM; Perez, F; Plummer, MS; Spencer, EJ; van den Akker, F; van Duin, D | 1 |
| Aoki, T; Komano, K; Kusano, H; Matsumoto, S; Oguma, T; Sato, J; Sato, T; Shibuya, S; Yamawaki, K; Yasuo, K; Yokoo, K | 1 |
1 review(s) available for aztreonam and ceftazidime
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
163 other study(ies) available for aztreonam and ceftazidime
| Article | Year |
|---|---|
The acylating potential of gamma-lactam antibacterials: base hydrolysis of bicyclic pyrazolidinones.
Topics: Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Lactams; Spectrophotometry, Ultraviolet; Stereoisomerism; Structure-Activity Relationship | 1988 |
Structure-activity relationships of bivalent aminoglycosides and evaluation of their microbiological activities.
Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Drug Evaluation, Preclinical; Female; Humans; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Structure-Activity Relationship | 2005 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Novel Ambler class A beta-lactamase LAP-1 and its association with the plasmid-mediated quinolone resistance determinant QnrS1.
Topics: Amino Acid Sequence; Bacterial Proteins; beta-Lactam Resistance; beta-Lactamases; Cloning, Molecular; Enterobacter cloacae; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Molecular Sequence Data; Plasmids; Quinolones; Sequence Alignment | 2007 |
Plasmid-mediated KPC-2 in a Klebsiella pneumoniae isolate from China.
Topics: beta-Lactam Resistance; beta-Lactamases; Carbapenems; China; Hospitals, University; Humans; Klebsiella pneumoniae; Molecular Sequence Data; Plasmids | 2007 |
Antimicrobial susceptibility and synergy studies of Burkholderia cepacia complex isolated from patients with cystic fibrosis.
Topics: Anti-Bacterial Agents; Burkholderia cepacia complex; Burkholderia Infections; Cystic Fibrosis; Drug Resistance, Multiple, Bacterial; Drug Synergism; Humans; Microbial Sensitivity Tests | 2007 |
Coproduction of novel 16S rRNA methylase RmtD and metallo-beta-lactamase SPM-1 in a panresistant Pseudomonas aeruginosa isolate from Brazil.
Topics: Amino Acid Sequence; Aminoglycosides; beta-Lactamases; Brazil; Carbapenems; Cloning, Molecular; Drug Resistance, Multiple, Bacterial; Methyltransferases; Microbial Sensitivity Tests; Molecular Sequence Data; Plasmids; Pseudomonas aeruginosa; Pseudomonas Infections | 2007 |
Detection of a new SHV-type extended-spectrum beta-lactamase, SHV-31, in a Klebsiella pneumoniae strain causing a large nosocomial outbreak in The Netherlands.
Topics: Anti-Bacterial Agents; beta-Lactamases; Cross Infection; Disease Outbreaks; Drug Resistance, Multiple, Bacterial; Humans; Intensive Care Units; Isoelectric Focusing; Klebsiella Infections; Klebsiella pneumoniae; Microbial Sensitivity Tests; Molecular Sequence Data; Netherlands; Plasmids | 2007 |
Evolution of TEM-type enzymes: biochemical and genetic characterization of two new complex mutant TEM enzymes, TEM-151 and TEM-152, from a single patient.
Topics: beta-Lactamases; Drug Resistance, Bacterial; Escherichia coli; Evolution, Molecular; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Mutation | 2007 |
Prevalence of plasmid-mediated quinolone resistance determinants QnrA, QnrB, and QnrS among clinical isolates of Enterobacter cloacae in a Taiwanese hospital.
Topics: Anti-Bacterial Agents; beta-Lactamases; Drug Resistance, Bacterial; Enterobacter cloacae; Enterobacteriaceae Infections; Genes, Bacterial; Hospitals; Microbial Sensitivity Tests; Molecular Sequence Data; Plasmids; Prevalence; Quinolones; Taiwan | 2007 |
Chromosome-encoded narrow-spectrum Ambler class A beta-lactamase GIL-1 from Citrobacter gillenii.
Topics: beta-Lactamases; Chromosomes; Chromosomes, Bacterial; Citrobacter; Cloning, Molecular; DNA, Bacterial; Escherichia coli; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Genes, Bacterial; Molecular Sequence Data | 2007 |
Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients.
Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Drug Resistance, Bacterial; Humans; Longitudinal Studies; Pneumonia, Ventilator-Associated; Polymerase Chain Reaction; Pseudomonas aeruginosa; Pseudomonas Infections | 2007 |
First identification of Pseudomonas aeruginosa isolates producing a KPC-type carbapenem-hydrolyzing beta-lactamase.
Topics: beta-Lactamases; Carbapenems; Drug Resistance, Bacterial; Hydrolysis; Microbial Sensitivity Tests; Pseudomonas aeruginosa | 2007 |
SCO-1, a novel plasmid-mediated class A beta-lactamase with carbenicillinase characteristics from Escherichia coli.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamases; beta-Lactams; Escherichia coli; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Penicillinase; Plasmids; Sequence Analysis, DNA | 2007 |
Spread of extended-spectrum beta-lactamase CTX-M-producing escherichia coli clinical isolates in community and nosocomial environments in Portugal.
Topics: Aged; Anti-Bacterial Agents; beta-Lactamases; Community-Acquired Infections; Cross Infection; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Humans; Microbial Sensitivity Tests; Middle Aged; Portugal | 2007 |
Predictors of mortality in patients with bloodstream infections caused by extended-spectrum-beta-lactamase-producing Enterobacteriaceae: importance of inadequate initial antimicrobial treatment.
Topics: Adult; Aged; Anti-Bacterial Agents; Bacteremia; beta-Lactamases; Cross Infection; Drug Resistance, Bacterial; Enterobacteriaceae; Enterobacteriaceae Infections; Escherichia coli; Female; Humans; Klebsiella pneumoniae; Male; Microbial Sensitivity Tests; Middle Aged; Predictive Value of Tests; Proteus mirabilis; Risk Factors; Survival Analysis; Treatment Outcome | 2007 |
Spread in an Italian hospital of a clonal Acinetobacter baumannii strain producing the TEM-92 extended-spectrum beta-lactamase.
Topics: Acinetobacter baumannii; Acinetobacter Infections; Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamases; beta-Lactams; Cross Infection; Humans; Italy; Microbial Sensitivity Tests | 2007 |
Effects of carbapenem exposure on the risk for digestive tract carriage of intensive care unit-endemic carbapenem-resistant Pseudomonas aeruginosa strains in critically ill patients.
Topics: Adult; Aged; Anti-Bacterial Agents; beta-Lactam Resistance; Carbapenems; Carrier State; Critical Illness; Endemic Diseases; Female; Gastrointestinal Tract; Humans; Imipenem; Incidence; Intensive Care Units; Male; Middle Aged; Pharynx; Pseudomonas aeruginosa; Pseudomonas Infections; Rectum; Risk Factors | 2007 |
Identification of the novel narrow-spectrum beta-lactamase SCO-1 in Acinetobacter spp. from Argentina.
Topics: Acinetobacter; Acinetobacter Infections; Amino Acid Sequence; Anti-Bacterial Agents; Argentina; beta-Lactam Resistance; beta-Lactamases; beta-Lactams; Clavulanic Acid; Cloning, Molecular; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Sequence Analysis, DNA | 2007 |
Biochemical characterization of PER-2 and genetic environment of blaPER-2.
Topics: Amino Acid Sequence; Base Sequence; beta-Lactam Resistance; beta-Lactamases; Catalysis; Citrobacter freundii; Conjugation, Genetic; DNA, Bacterial; DNA, Recombinant; Enterobacteriaceae; Genes, Bacterial; Humans; Hydrolysis; Isoelectric Focusing; Kinetics; Mass Spectrometry; Microbial Sensitivity Tests; Molecular Sequence Data; Molecular Weight; Plasmids; Polymerase Chain Reaction; Promoter Regions, Genetic; Protein Conformation; Protein Sorting Signals; Sequence Analysis, DNA | 2007 |
blaVIM-2-harboring integrons isolated in India, Russia, and the United States arise from an ancestral class 1 integron predating the formation of the 3' conserved sequence.
Topics: Base Sequence; beta-Lactamases; DNA Transposable Elements; Evolution, Molecular; Genes, Bacterial; Humans; India; Integrons; Molecular Sequence Data; Pseudomonas aeruginosa; Russia; United States | 2007 |
Enterobacteriaceae bloodstream infections: presence of integrons, risk factors, and outcome.
Topics: Bacteremia; Community-Acquired Infections; Cross Infection; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Enterobacteriaceae Infections; Gene Transfer, Horizontal; Humans; Infectious Disease Transmission, Professional-to-Patient; Integrons; Microbial Sensitivity Tests; Nucleic Acid Amplification Techniques; Polymerase Chain Reaction; Prospective Studies; Risk Factors; Sequence Analysis, DNA; Treatment Outcome | 2007 |
Extended-spectrum beta-lactamases of the CTX-M type now in Switzerland.
Topics: Anti-Bacterial Agents; beta-Lactamases; Community-Acquired Infections; Enterobacteriaceae; Enterobacteriaceae Infections; Escherichia coli; Hospitals, University; Humans; Microbial Sensitivity Tests; Molecular Epidemiology; Polymerase Chain Reaction; Prevalence; Switzerland | 2007 |
Identification and characterization of a new metallo-beta-lactamase, IND-5, from a clinical isolate of Chryseobacterium indologenes.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamases; Carbapenems; Cephalosporins; Chryseobacterium; Flavobacteriaceae Infections; Humans; Kinetics; Microbial Sensitivity Tests; Molecular Sequence Data; Penicillins; Sequence Analysis, DNA | 2007 |
Influence of high mutation rates on the mechanisms and dynamics of in vitro and in vivo resistance development to single or combined antipseudomonal agents.
Topics: Animals; Anti-Bacterial Agents; Ceftazidime; Ciprofloxacin; Disease Models, Animal; Drug Resistance, Microbial; Drug Synergism; Drug Therapy, Combination; Female; Humans; In Vitro Techniques; Lung; Mice; Mice, Inbred C57BL; Microbial Sensitivity Tests; Mutation; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin | 2007 |
Binding of ceftobiprole and comparators to the penicillin-binding proteins of Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, and Streptococcus pneumoniae.
Topics: Bacterial Proteins; Cephalosporins; Escherichia coli Proteins; Gram-Negative Bacteria; Inhibitory Concentration 50; Microbial Sensitivity Tests; Penicillin-Binding Proteins; Pseudomonas aeruginosa; Staphylococcus aureus; Streptococcus pneumoniae | 2007 |
Characterization of an integron carrying blaIMP-1 and a new aminoglycoside resistance gene, aac(6')-31, and its dissemination among genetically unrelated clinical isolates in a Brazilian hospital.
Topics: Acinetobacter; Amino Acid Sequence; Aminoglycosides; Anti-Bacterial Agents; Base Sequence; Brazil; Codon, Terminator; Cross Infection; Drug Resistance, Multiple, Bacterial; Gene Transfer, Horizontal; Genes, Bacterial; Hospitals; Humans; Integrons; Microbial Sensitivity Tests; Molecular Sequence Data; Open Reading Frames; Plasmids; Pseudomonas putida; Transcription, Genetic | 2007 |
First occurrence of an Escherichia coli clinical isolate producing the VIM-1/VIM-2 hybrid metallo-beta-lactamase VIM-12.
Topics: Aged, 80 and over; Anti-Bacterial Agents; beta-Lactamases; Conjugation, Genetic; Escherichia coli; Escherichia coli Infections; Humans; Male; Microbial Sensitivity Tests; Plasmids; Recombination, Genetic | 2007 |
Novel complex class 1 integron bearing an ISCR1 element in an Escherichia coli isolate carrying the blaCTX-M-14 gene.
Topics: Adult; Anti-Bacterial Agents; Base Sequence; beta-Lactamases; DNA Transposable Elements; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Humans; Integrons; Male; Microbial Sensitivity Tests; Molecular Sequence Data; Pneumonia, Bacterial; Sequence Analysis, DNA | 2007 |
Sequencing and comparative genomic analysis of pK29, a 269-kilobase conjugative plasmid encoding CMY-8 and CTX-M-3 beta-lactamases in Klebsiella pneumoniae.
Topics: Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamases; Conjugation, Genetic; Genomics; Humans; Klebsiella pneumoniae; Microbial Sensitivity Tests; Molecular Sequence Data; Plasmids; Sequence Analysis, DNA | 2007 |
Emergence of KPC-2 and KPC-3 in carbapenem-resistant Klebsiella pneumoniae strains in an Israeli hospital.
Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactam Resistance; beta-Lactamases; Carbapenems; Hospitals; Humans; Israel; Klebsiella Infections; Klebsiella pneumoniae; Microbial Sensitivity Tests; Molecular Epidemiology | 2007 |
Colistin methanesulfonate against multidrug-resistant Acinetobacter baumannii in an in vitro pharmacodynamic model.
Topics: Acinetobacter baumannii; Anti-Bacterial Agents; Ceftazidime; Colistin; Colony Count, Microbial; Drug Combinations; Drug Resistance, Multiple, Bacterial; Microbial Sensitivity Tests | 2007 |
Molecular epidemiology of imipenem-resistant Acinetobacter haemolyticus and Acinetobacter baumannii isolates carrying plasmid-mediated OXA-40 from a Portuguese hospital.
Topics: Acinetobacter; Acinetobacter baumannii; Acinetobacter Infections; Bacterial Proteins; beta-Lactamases; Cross Infection; Humans; Plasmids; Portugal | 2007 |
Cloning, nucleotide sequencing, and analysis of the AcrAB-TolC efflux pump of Enterobacter cloacae and determination of its involvement in antibiotic resistance in a clinical isolate.
Topics: Bacterial Proteins; Base Sequence; beta-Lactamases; Carrier Proteins; Cloning, Molecular; DNA, Bacterial; Drug Resistance, Bacterial; Enterobacter cloacae; Enterobacteriaceae Infections; Genes, MDR; Genetic Vectors; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Plasmids; Porins | 2007 |
Plasmid-encoded ACC-4, an extended-spectrum cephalosporinase variant from Escherichia coli.
Topics: Anti-Bacterial Agents; Cephalosporinase; Culture Media; DNA Primers; Drug Resistance, Bacterial; Escherichia coli; Kinetics; Models, Molecular; Molecular Sequence Data; Plasmids; Reverse Transcriptase Polymerase Chain Reaction; Spectrophotometry, Ultraviolet | 2007 |
Pseudomonas aeruginosa may accumulate drug resistance mechanisms without losing its ability to cause bloodstream infections.
Topics: Aminoglycosides; Anti-Bacterial Agents; Bacteremia; beta-Lactams; DNA, Bacterial; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Fluoroquinolones; Genotype; Humans; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Reverse Transcriptase Polymerase Chain Reaction | 2007 |
TEM-158 (CMT-9), a new member of the CMT-type extended-spectrum beta-lactamases.
Topics: beta-Lactam Resistance; beta-Lactamases; beta-Lactams; Catalysis; Ceftazidime; Clavulanic Acid; Escherichia coli; Escherichia coli Proteins; Isoenzymes; Kinetics; Microbial Sensitivity Tests; Molecular Sequence Data; Sequence Analysis, DNA | 2007 |
An OXA-66/OXA-51-like carbapenemase and possibly an efflux pump are associated with resistance to imipenem in Acinetobacter baumannii.
Topics: Acinetobacter baumannii; Acinetobacter Infections; Bacterial Proteins; Base Sequence; beta-Lactamases; Drug Resistance, Bacterial; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Gene Expression Regulation, Bacterial; Humans; Imipenem; Microbial Sensitivity Tests; Molecular Sequence Data; Mutation; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Homology, Nucleic Acid | 2007 |
Molecular and biochemical characterization of the chromosome-encoded class A beta-lactamase BCL-1 from Bacillus clausii.
Topics: Amino Acid Sequence; Bacillus; Bacterial Proteins; beta-Lactamases; Chromosome Mapping; Chromosomes, Bacterial; Cloning, Molecular; Microbial Sensitivity Tests; Molecular Sequence Data; Molecular Weight; Sequence Homology, Amino Acid; Substrate Specificity | 2007 |
Biochemical Characterization of SFC-1, a class A carbapenem-hydrolyzing beta-lactamase.
Topics: Aztreonam; beta-Lactamases; Carbapenems; Catalysis; Cephalosporins; Clavulanic Acid; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Hydrolysis; Kinetics; Molecular Weight; Penicillanic Acid; Penicillins; Recombinant Proteins; Serratia; Sulbactam; Tazobactam | 2007 |
First occurrence of an IMP metallo-beta-lactamase in Aeromonas caviae: IMP-19 in an isolate from France.
Topics: Aeromonas; Anti-Bacterial Agents; beta-Lactamases; beta-Lactams; France; Integrons; Kinetics; Microbial Sensitivity Tests; Molecular Sequence Data; Plasmids; Sequence Analysis, DNA; Substrate Specificity | 2007 |
Molecular epidemiology and mechanisms of carbapenem resistance in Pseudomonas aeruginosa isolates from Spanish hospitals.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactam Resistance; beta-Lactamases; Carbapenems; Chromosomes, Bacterial; Cross Infection; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Integrons; Molecular Epidemiology; Molecular Sequence Data; Mutation; Plasmids; Polymerase Chain Reaction; Porins; Pseudomonas aeruginosa; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Spain | 2007 |
RmtC 16S rRNA methyltransferase in Australia.
Topics: Aminoglycosides; Anti-Bacterial Agents; Australia; beta-Lactam Resistance; beta-Lactamases; beta-Lactams; Drug Resistance, Bacterial; Genes, rRNA; Humans; Methyltransferases; Microbial Sensitivity Tests; Proteus Infections; Proteus mirabilis; RNA, Ribosomal, 16S | 2008 |
Plasmid-mediated carbapenem-hydrolyzing beta-lactamase KPC-2 in Klebsiella pneumoniae isolate from Greece.
Topics: Adult; Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamases; beta-Lactams; Carbapenems; Female; Greece; Humans; Klebsiella Infections; Klebsiella pneumoniae; Microbial Sensitivity Tests; Plasmids | 2008 |
Genetic and biochemical characterization of CAD-1, a chromosomally encoded new class A penicillinase from Carnobacterium divergens.
Topics: Amino Acid Sequence; beta-Lactams; Chromosomes, Bacterial; Cloning, Molecular; Electrophoresis, Gel, Pulsed-Field; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Infant, Newborn; Kinetics; Microbial Sensitivity Tests; Molecular Sequence Data; Penicillin Resistance; Penicillinase; Sequence Alignment; Sequence Analysis, DNA; Substrate Specificity | 2008 |
E240V substitution increases catalytic efficiency toward ceftazidime in a new natural TEM-type extended-spectrum beta-lactamase, TEM-149, from Enterobacter aerogenes and Serratia marcescens clinical isolates.
Topics: Amino Acid Substitution; Anti-Bacterial Agents; beta-Lactamases; beta-Lactams; Catalysis; Ceftazidime; Enterobacter aerogenes; Humans; Kinetics; Microbial Sensitivity Tests; Models, Molecular; Molecular Sequence Data; Sequence Analysis, DNA; Serratia marcescens; Structure-Activity Relationship; Substrate Specificity | 2008 |
Genetic and biochemical characterization of OXA-63, a new class D beta-lactamase from Brachyspira pilosicoli BM4442.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; Base Sequence; beta-Lactamases; Brachyspira; Cloning, Molecular; Diarrhea; Feces; Gram-Negative Bacterial Infections; Humans; Kinetics; Molecular Sequence Data; Oxacillin; Penicillin Resistance; Sequence Analysis, DNA | 2008 |
Genetic structures at the origin of acquisition of the beta-lactamase bla KPC gene.
Topics: Base Sequence; beta-Lactamases; beta-Lactams; Cloning, Molecular; Colombia; DNA Transposable Elements; Greece; Humans; Klebsiella Infections; Klebsiella pneumoniae; Microbial Sensitivity Tests; Molecular Sequence Data; Pseudomonas aeruginosa; Pseudomonas Infections; Sequence Analysis, DNA; United States | 2008 |
Affinity of doripenem and comparators to penicillin-binding proteins in Escherichia coli and Pseudomonas aeruginosa.
Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactams; Carbapenems; Doripenem; Escherichia coli; Escherichia coli Proteins; Humans; Inhibitory Concentration 50; Microbial Sensitivity Tests; Penicillin-Binding Proteins; Pseudomonas aeruginosa | 2008 |
Outbreak of Acinetobacter baumannii with chromosomally encoded VIM-1 undetectable by imipenem-EDTA synergy tests.
Topics: Acinetobacter baumannii; Acinetobacter Infections; Anti-Bacterial Agents; beta-Lactamases; Carbapenems; Chromosomes, Bacterial; Cross Infection; Disease Outbreaks; DNA, Bacterial; Drug Resistance, Bacterial; Edetic Acid; Greece; Humans; Imipenem; Integrons; Isoelectric Focusing; Microbial Sensitivity Tests; Molecular Sequence Data; Sequence Analysis, DNA | 2008 |
Carbapenem-resistant Acinetobacter baumannii isolates from Tunisia producing the OXA-58-like carbapenem-hydrolyzing oxacillinase OXA-97.
Topics: Acinetobacter baumannii; Africa; Bacterial Proteins; beta-Lactamases; Blotting, Southern; Carbapenems; Cross Infection; Drug Resistance, Bacterial; Humans; Microbial Sensitivity Tests; Models, Genetic; Molecular Sequence Data; Polymerase Chain Reaction; Tunisia | 2008 |
The Lys234Arg substitution in the enzyme SHV-72 is a determinant for resistance to clavulanic acid inhibition.
Topics: Amino Acid Substitution; Amoxicillin; Anti-Bacterial Agents; Arginine; Aztreonam; Bacterial Proteins; beta-Lactamase Inhibitors; beta-Lactamases; Cephalosporins; Clavulanic Acid; Computer Simulation; Imipenem; Isoelectric Focusing; Kinetics; Klebsiella pneumoniae; Lysine; Microbial Sensitivity Tests; Models, Molecular; Molecular Sequence Data; Penicillins; Protein Conformation; Protein Structure, Tertiary | 2008 |
Biochemical characterization of SHV-55, an extended-spectrum class A beta-lactamase from Klebsiella pneumoniae.
Topics: Anti-Bacterial Agents; beta-Lactamases; Kinetics; Klebsiella pneumoniae | 2008 |
Emergence of Serratia marcescens, Klebsiella pneumoniae, and Escherichia coli Isolates possessing the plasmid-mediated carbapenem-hydrolyzing beta-lactamase KPC-2 in intensive care units of a Chinese hospital.
Topics: Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamases; beta-Lactams; Carbapenems; China; Conjugation, Genetic; Electrophoresis, Gel, Pulsed-Field; Escherichia coli; Hospitals, University; Humans; Hydrolysis; Intensive Care Units; Klebsiella pneumoniae; Microbial Sensitivity Tests; Plasmids; Polymerase Chain Reaction; Serratia marcescens | 2008 |
Multiclonal outbreak of Klebsiella pneumoniae producing extended-spectrum beta-lactamase CTX-M-2 and novel variant CTX-M-59 in a neonatal intensive care unit in Brazil.
Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Brazil; Cephalosporins; Disease Outbreaks; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Humans; Infant, Newborn; Intensive Care Units, Neonatal; Klebsiella Infections; Klebsiella pneumoniae; Microbial Sensitivity Tests; Molecular Sequence Data; Mutation; Polymerase Chain Reaction | 2008 |
Biochemical characterization of metallo-beta-lactamase VIM-11 from a Pseudomonas aeruginosa clinical strain.
Topics: beta-Lactam Resistance; beta-Lactamases; beta-Lactams; Binding Sites; Escherichia coli; Humans; Kinetics; Microbial Sensitivity Tests; Models, Molecular; Plasmids; Pseudomonas aeruginosa; Pseudomonas Infections | 2008 |
Characterization of a naturally occurring class D beta-lactamase from Achromobacter xylosoxidans.
Topics: Achromobacter denitrificans; Amino Acid Sequence; Anti-Bacterial Agents; beta-Lactamases; beta-Lactams; Cloning, Molecular; Humans; Kinetics; Microbial Sensitivity Tests; Molecular Sequence Data; Sequence Analysis, DNA | 2008 |
Presence of plasmid-mediated quinolone resistance in Klebsiella pneumoniae isolates possessing blaKPC in the United States.
Topics: Aged; Bacterial Proteins; Base Sequence; beta-Lactamases; DNA Primers; DNA, Bacterial; Drug Resistance, Bacterial; Genes, Bacterial; Humans; Klebsiella Infections; Klebsiella pneumoniae; Male; Microbial Sensitivity Tests; Molecular Epidemiology; Plasmids; Quinolones; United States | 2008 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Acquisition of a plasmid-borne blaOXA-58 gene with an upstream IS1008 insertion conferring a high level of carbapenem resistance to Acinetobacter baumannii.
Topics: Acinetobacter baumannii; Acinetobacter Infections; Base Sequence; beta-Lactam Resistance; beta-Lactamases; Carbapenems; Cross Infection; DNA Primers; DNA Transposable Elements; DNA, Bacterial; Genes, Bacterial; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Plasmids; Promoter Regions, Genetic; Transformation, Genetic | 2008 |
Functional diversity among metallo-beta-lactamases: characterization of the CAR-1 enzyme of Erwinia carotovora.
Topics: Amino Acid Sequence; Bacterial Proteins; Base Sequence; beta-Lactamases; Cloning, Molecular; DNA Primers; DNA, Bacterial; Drug Resistance, Bacterial; Genes, Bacterial; Molecular Sequence Data; Open Reading Frames; Pectobacterium carotovorum; Phenotype; Phylogeny; Recombinant Proteins; Sequence Homology, Amino Acid | 2008 |
Metallo-beta-lactamase gene bla(IMP-15) in a class 1 integron, In95, from Pseudomonas aeruginosa clinical isolates from a hospital in Mexico.
Topics: Bacterial Proteins; beta-Lactamases; Cross Infection; Electrophoresis, Gel, Pulsed-Field; Humans; Integrons; Mexico; Models, Genetic; Molecular Sequence Data; Pseudomonas aeruginosa; Pseudomonas Infections | 2008 |
Spread of OXA-48-positive carbapenem-resistant Klebsiella pneumoniae isolates in Istanbul, Turkey.
Topics: Bacterial Proteins; beta-Lactamases; Carbapenems; Cross Infection; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Humans; Klebsiella Infections; Klebsiella pneumoniae; Microbial Sensitivity Tests; Models, Genetic; Turkey | 2008 |
Plasmid-mediated qnrB2 and carbapenemase gene bla(KPC-2) carried on the same plasmid in carbapenem-resistant ciprofloxacin-susceptible Enterobacter cloacae isolates.
Topics: Anti-Infective Agents; Bacterial Proteins; beta-Lactamases; Carbapenems; Ciprofloxacin; Drug Resistance, Bacterial; Enterobacter cloacae; Genes, Bacterial; Microbial Sensitivity Tests; Plasmids; Quinolones | 2008 |
VIM-15 and VIM-16, two new VIM-2-like metallo-beta-lactamases in Pseudomonas aeruginosa isolates from Bulgaria and Germany.
Topics: Amino Acid Substitution; Bacterial Proteins; beta-Lactamases; Bulgaria; Catalysis; Germany; Hydrolysis; Isoenzymes; Kinetics; Microbial Sensitivity Tests; Molecular Sequence Data; Pseudomonas aeruginosa; Sequence Analysis, DNA | 2008 |
Kinetic characterization of VIM-7, a divergent member of the VIM metallo-beta-lactamase family.
Topics: Acremonium; Bacterial Proteins; beta-Lactamases; Catalysis; Catalytic Domain; Cefepime; Ceftazidime; Cephalosporins; Kinetics; Models, Molecular; Mutation; Penicillinase; Protein Structure, Tertiary; Recombinant Proteins; Structure-Activity Relationship; Substrate Specificity | 2008 |
Correlation of antimicrobial resistance with beta-lactamases, the OmpA-like porin, and efflux pumps in clinical isolates of Acinetobacter baumannii endemic to New York City.
Topics: Acinetobacter baumannii; Acinetobacter Infections; Anti-Bacterial Agents; Bacterial Outer Membrane Proteins; Bacterial Proteins; beta-Lactamases; Drug Resistance, Bacterial; Endemic Diseases; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; New York City; Sequence Analysis, DNA | 2008 |
Genetic and structural insights into the dissemination potential of the extremely broad-spectrum class A beta-lactamase KPC-2 identified in an Escherichia coli strain and an Enterobacter cloacae strain isolated from the same patient in France.
Topics: Aged; Base Sequence; beta-Lactam Resistance; beta-Lactamases; beta-Lactams; Catalytic Domain; Cephalosporin Resistance; Crystallography, X-Ray; DNA Primers; DNA, Bacterial; Enterobacter cloacae; Enterobacteriaceae Infections; Escherichia coli; Escherichia coli Infections; France; Genes, Bacterial; Humans; Imipenem; Kinetics; Male; Models, Molecular; Mutation | 2008 |
Characterization of the new metallo-beta-lactamase VIM-13 and its integron-borne gene from a Pseudomonas aeruginosa clinical isolate in Spain.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; Bacterial Proteins; Base Sequence; beta-Lactam Resistance; beta-Lactamases; Cloning, Molecular; DNA Primers; DNA, Bacterial; Genes, Bacterial; Genetic Variation; Humans; Imipenem; Integrons; Kinetics; Meropenem; Molecular Sequence Data; Phylogeny; Pseudomonas aeruginosa; Pseudomonas Infections; Recombinant Proteins; Sequence Homology, Amino Acid; Spain; Thienamycins | 2008 |
Plasmid-mediated quinolone resistance pump QepA2 in an Escherichia coli isolate from France.
Topics: Aged; Base Sequence; DNA Primers; DNA, Bacterial; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Female; Fluoroquinolones; France; Genes, Bacterial; Humans; Models, Genetic; Molecular Sequence Data; Plasmids | 2008 |
Plasmid-encoded carbapenem-hydrolyzing beta-lactamase OXA-48 in an imipenem-susceptible Klebsiella pneumoniae strain from Belgium.
Topics: Adult; Anti-Bacterial Agents; Belgium; beta-Lactamases; beta-Lactams; Carbapenems; Humans; Imipenem; Klebsiella Infections; Klebsiella pneumoniae; Male; Microbial Sensitivity Tests; Plasmids | 2008 |
Molecular and biochemical characterization of SHV-56, a novel inhibitor-resistant beta-lactamase from Klebsiella pneumoniae.
Topics: Aged; Amino Acid Substitution; Base Sequence; beta-Lactam Resistance; beta-Lactamases; DNA Primers; DNA, Bacterial; Female; Genes, Bacterial; Humans; Isoelectric Point; Kinetics; Klebsiella Infections; Klebsiella pneumoniae; Molecular Sequence Data; Mutagenesis, Insertional; Recombinant Proteins | 2008 |
Macrolide antibiotic-mediated downregulation of MexAB-OprM efflux pump expression in Pseudomonas aeruginosa.
Topics: Anti-Bacterial Agents; Azithromycin; Bacterial Outer Membrane Proteins; Down-Regulation; Humans; Macrolides; Membrane Transport Proteins; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Quorum Sensing | 2008 |
KHM-1, a novel plasmid-mediated metallo-beta-lactamase from a Citrobacter freundii clinical isolate.
Topics: Amino Acid Sequence; Base Sequence; beta-Lactam Resistance; beta-Lactamases; Citrobacter freundii; Conjugation, Genetic; DNA Primers; DNA, Bacterial; Enterobacteriaceae Infections; Escherichia coli K12; Genes, Bacterial; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Phylogeny; Plasmids; Recombinant Proteins; Sequence Homology, Amino Acid | 2008 |
Role of ampD homologs in overproduction of AmpC in clinical isolates of Pseudomonas aeruginosa.
Topics: Amino Acid Sequence; Bacterial Proteins; Base Sequence; beta-Lactam Resistance; beta-Lactamases; DNA Primers; DNA, Bacterial; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Genes, Bacterial; Genetic Complementation Test; Humans; Molecular Sequence Data; N-Acetylmuramoyl-L-alanine Amidase; Pseudomonas aeruginosa; Pseudomonas Infections; RNA, Bacterial; Sequence Homology, Amino Acid | 2008 |
First countrywide survey of acquired metallo-beta-lactamases in gram-negative pathogens in Italy.
Topics: Base Sequence; beta-Lactam Resistance; beta-Lactamases; Data Collection; DNA Primers; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Genes, Bacterial; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Humans; Integrons; Italy; Molecular Epidemiology; Molecular Sequence Data | 2008 |
Novel chimeric beta-lactamase CTX-M-64, a hybrid of CTX-M-15-like and CTX-M-14 beta-lactamases, found in a Shigella sonnei strain resistant to various oxyimino-cephalosporins, including ceftazidime.
Topics: Amino Acid Sequence; beta-Lactamases; Blotting, Southern; Ceftazidime; Cephalosporins; Kinetics; Microbial Sensitivity Tests; Molecular Sequence Data; Polymerase Chain Reaction; Sequence Homology, Amino Acid; Shigella sonnei | 2009 |
Relative strengths of the class 1 integron promoter hybrid 2 and the combinations of strong and hybrid 1 with an active p2 promoter.
Topics: beta-Lactamases; beta-Lactams; Integrons; Microbial Sensitivity Tests; Promoter Regions, Genetic; Pseudomonas aeruginosa | 2009 |
Detection of the pandemic O25-ST131 human virulent Escherichia coli CTX-M-15-producing clone harboring the qnrB2 and aac(6')-Ib-cr genes in a dog.
Topics: Animals; Anti-Bacterial Agents; Dogs; Drug Resistance, Bacterial; Escherichia coli; Genes, Bacterial; Humans; Plasmids; Virulence | 2009 |
Role of the Ser-287-Asn replacement in the hydrolysis spectrum extension of AmpC beta-lactamases in Escherichia coli.
Topics: Asparagine; Bacterial Proteins; beta-Lactamases; Cephalosporins; Escherichia coli; Escherichia coli Proteins; Hydrolysis; Microbial Sensitivity Tests; Models, Molecular; Mutagenesis, Site-Directed; Protein Structure, Secondary; Serine | 2009 |
Codetection of blaOXA-23-like gene (blaOXA-133) and blaOXA-58 in Acinetobacter radioresistens: report from the SENTRY antimicrobial surveillance program.
Topics: Acinetobacter; Anti-Bacterial Agents; beta-Lactamases; Drug Resistance, Bacterial; Molecular Sequence Data; Plasmids; Population Surveillance; Reverse Transcriptase Polymerase Chain Reaction; Transcription, Genetic | 2009 |
First report of KPC-2-producing Klebsiella pneumoniae strains in Brazil.
Topics: beta-Lactamases; Brazil; Carbapenems; Klebsiella pneumoniae | 2009 |
Phenotypic and enzymatic comparative analysis of the novel KPC variant KPC-5 and its evolutionary variants, KPC-2 and KPC-4.
Topics: Amino Acid Substitution; Anti-Bacterial Agents; Bacteremia; beta-Lactamase Inhibitors; beta-Lactamases; Clavulanic Acid; Drug Resistance, Bacterial; Enzyme Inhibitors; Genetic Variation; Hydrolysis; Isoelectric Focusing; Klebsiella pneumoniae; Microbial Sensitivity Tests; Phenotype; Protein Isoforms; Reverse Transcriptase Polymerase Chain Reaction | 2009 |
Genetic variability among ampC genes from acinetobacter genomic species 3.
Topics: Acinetobacter; Acinetobacter baumannii; Amino Acid Sequence; Ampicillin Resistance; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactam Resistance; Escherichia coli; Genes, Bacterial; Genetic Variation; Humans; Kinetics; Microbial Sensitivity Tests; Models, Molecular; Molecular Sequence Data; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Sequence Homology, Amino Acid; Spain | 2009 |
Pyrosequencing using the single-nucleotide polymorphism protocol for rapid determination of TEM- and SHV-type extended-spectrum beta-lactamases in clinical isolates and identification of the novel beta-lactamase genes blaSHV-48, blaSHV-105, and blaTEM-155
Topics: Amino Acid Sequence; Amino Acid Substitution; Anti-Bacterial Agents; beta-Lactamases; Enterobacteriaceae; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Plasmids; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Reproducibility of Results; Time Factors | 2009 |
Naturally occurring Class A ss-lactamases from the Burkholderia cepacia complex.
Topics: Alleles; Amino Acid Sequence; Amino Acid Substitution; Base Sequence; beta-Lactamases; Burkholderia cepacia complex; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Humans; Hydrolysis; Isoelectric Point; Kinetics; Microbial Sensitivity Tests; Molecular Sequence Data; Phylogeny; Plasmids; Sequence Analysis, DNA; Sequence Homology, Amino Acid | 2009 |
CMY-31 and CMY-36 cephalosporinases encoded by ColE1-like plasmids.
Topics: Alleles; Amino Acid Sequence; Amino Acid Substitution; Arginine; Base Sequence; beta-Lactamase Inhibitors; beta-Lactamases; Cephalosporinase; Citrobacter freundii; Cysteine; DNA Transposable Elements; DNA, Bacterial; Escherichia coli; Genes, Bacterial; Glutamine; Humans; Hydrolysis; Inhibitory Concentration 50; Isoelectric Point; Kinetics; Klebsiella pneumoniae; Microbial Sensitivity Tests; Models, Genetic; Models, Molecular; Molecular Sequence Data; Plasmids; Salmonella enterica; Sequence Analysis, DNA; Species Specificity; Substrate Specificity; Transformation, Genetic | 2009 |
Carbapenem resistance among Pseudomonas aeruginosa strains from India: evidence for nationwide endemicity of multiple metallo-beta-lactamase clones (VIM-2, -5, -6, and -11 and the newly characterized VIM-18).
Topics: Anti-Bacterial Agents; Bacterial Proteins; Base Sequence; beta-Lactamases; Carbapenems; Drug Resistance, Bacterial; Humans; India; Microbial Sensitivity Tests; Molecular Sequence Data; Prevalence; Pseudomonas aeruginosa; Ribotyping | 2009 |
Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.
Topics: Anti-Bacterial Agents; Azithromycin; Bacterial Proteins; Biofilms; Cefepime; Cephalosporins; Ciprofloxacin; Cystic Fibrosis; DNA-Binding Proteins; Humans; Membrane Proteins; Membrane Transport Proteins; Microbial Sensitivity Tests; Mutation; MutS DNA Mismatch-Binding Protein; Pseudomonas aeruginosa; Transcription Factors | 2009 |
First organisms with acquired metallo-beta-lactamases (IMP-13, IMP-22, and VIM-2) reported in Austria.
Topics: Austria; Bacterial Proteins; beta-Lactam Resistance; beta-Lactamases; beta-Lactams; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Pseudomonas aeruginosa; Pseudomonas Infections; Sequence Analysis, DNA | 2009 |
Genetic organization of transposase regions surrounding blaKPC carbapenemase genes on plasmids from Klebsiella strains isolated in a New York City hospital.
Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Carbapenems; DNA Transposable Elements; Drug Resistance, Bacterial; Hospitals, Urban; Humans; Isoenzymes; Klebsiella Infections; Klebsiella oxytoca; Klebsiella pneumoniae; Microbial Sensitivity Tests; New York City; Plasmids; Transposases | 2009 |
Extended-spectrum cephalosporinases in Pseudomonas aeruginosa.
Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactam Resistance; beta-Lactamases; beta-Lactams; Ceftazidime; Cephalosporinase; Humans; Imipenem; Microbial Sensitivity Tests; Molecular Sequence Data; Pseudomonas aeruginosa; Sequence Analysis, DNA | 2009 |
Efflux unbalance in Pseudomonas aeruginosa isolates from cystic fibrosis patients.
Topics: Aminoglycosides; Anti-Bacterial Agents; Bacterial Outer Membrane Proteins; Bacterial Proteins; beta-Lactams; Cystic Fibrosis; Gene Expression Regulation, Bacterial; Humans; Membrane Transport Proteins; Microbial Sensitivity Tests; Mutation; Pseudomonas aeruginosa; Pseudomonas Infections; Sputum | 2009 |
Inactivation of the glycoside hydrolase NagZ attenuates antipseudomonal beta-lactam resistance in Pseudomonas aeruginosa.
Topics: Acetylglucosamine; Bacterial Proteins; beta-Lactam Resistance; beta-Lactamases; Glycoside Hydrolases; Microbial Sensitivity Tests; Oximes; Phenylcarbamates; Pseudomonas aeruginosa | 2009 |
Novel plasmid-encoded ceftazidime-hydrolyzing CTX-M-53 extended-spectrum beta-lactamase from Salmonella enterica serotypes Westhampton and Senftenberg.
Topics: Animals; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Cardiidae; Ceftazidime; Ceftriaxone; Cephalosporin Resistance; Electrophoresis, Gel, Pulsed-Field; France; Microbial Sensitivity Tests; Plasmids; Polymerase Chain Reaction; Salmonella enterica; Serotyping | 2009 |
Antibiotic resistance in Pseudomonas aeruginosa strains with increased mutation frequency due to inactivation of the DNA oxidative repair system.
Topics: Cystic Fibrosis; DNA Repair; Drug Resistance, Bacterial; Humans; Microbial Sensitivity Tests; Mutation; Neutrophil Activation; Oxidation-Reduction; Oxidative Stress; Pseudomonas aeruginosa | 2009 |
AAC(6')-Iaf, a novel aminoglycoside 6'-N-acetyltransferase from multidrug-resistant Pseudomonas aeruginosa clinical isolates.
Topics: Acetylation; Acetyltransferases; Aminoglycosides; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Humans; Integrons; Microbial Sensitivity Tests; Pseudomonas aeruginosa | 2009 |
First detection of plasmid-encoded blaOXY beta-lactamase.
Topics: beta-Lactamases; Blotting, Southern; Child, Preschool; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Humans; Klebsiella; Klebsiella oxytoca; Klebsiella pneumoniae; Male; Microbial Sensitivity Tests; Plasmids; Polymerase Chain Reaction | 2009 |
Genetic and biochemical characterization of the first extended-spectrum CARB-type beta-lactamase, RTG-4, from Acinetobacter baumannii.
Topics: Acinetobacter baumannii; Amino Acid Sequence; Anti-Bacterial Agents; beta-Lactamases; Drug Resistance, Bacterial; Escherichia coli; Kinetics; Microbial Sensitivity Tests; Molecular Sequence Data; Mutagenesis, Site-Directed | 2009 |
Reduced susceptibility to cefepime among Escherichia coli clinical isolates producing novel variants of CMY-2 beta-lactamase.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; beta-Lactamases; Cefepime; Cephalosporins; Escherichia coli; Microbial Sensitivity Tests; Molecular Sequence Data; Sequence Homology, Amino Acid | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
GES-11, a novel integron-associated GES variant in Acinetobacter baumannii.
Topics: Acinetobacter baumannii; Anti-Bacterial Agents; Aztreonam; beta-Lactamases; beta-Lactams; Carbapenems; Integrons; Microbial Sensitivity Tests; Models, Genetic; Molecular Sequence Data; Plasmids | 2009 |
Extended-spectrum properties of CMY-30, a Val211Gly mutant of CMY-2 cephalosporinase.
Topics: Aztreonam; beta-Lactamases; beta-Lactams; Ceftazidime; Cephalosporins; Escherichia coli Proteins; Protein Binding; Protein Structure, Secondary | 2009 |
Emerging Klebsiella pneumoniae isolates coproducing KPC-2 and VIM-1 carbapenemases.
Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; beta-Lactams; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Klebsiella pneumoniae; Polymerase Chain Reaction | 2009 |
Diversity of beta-lactamases produced by ceftazidime-resistant Pseudomonas aeruginosa isolates causing bloodstream infections in Brazil.
Topics: Aminoglycosides; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Brazil; Carbapenems; Ceftazidime; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Humans; Pseudomonas aeruginosa; Pseudomonas Infections; Quinolones | 2009 |
New variant of CTX-M-type extended-spectrum beta-lactamases, CTX-M-71, with a Gly238Cys substitution in a Klebsiella pneumoniae isolate from Bulgaria.
Topics: Anti-Bacterial Agents; beta-Lactamases; Bulgaria; Cefepime; Cefotaxime; Ceftazidime; Cephalosporins; Kinetics; Klebsiella pneumoniae; Microbial Sensitivity Tests; Molecular Sequence Data | 2009 |
IND-6, a highly divergent IND-type metallo-beta-lactamase from Chryseobacterium indologenes strain 597 isolated in Burkina Faso.
Topics: Adult; Amino Acid Sequence; Anti-Bacterial Agents; beta-Lactamases; Cefepime; Ceftazidime; Cephalexin; Cephalosporins; Cephalothin; Chryseobacterium; Female; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Phylogeny; Protein Structure, Secondary; Sequence Homology, Amino Acid | 2009 |
Complete nucleotide sequences of plasmids pEK204, pEK499, and pEK516, encoding CTX-M enzymes in three major Escherichia coli lineages from the United Kingdom, all belonging to the international O25:H4-ST131 clone.
Topics: beta-Lactamases; Computational Biology; Escherichia coli; Models, Genetic; Molecular Sequence Data; Open Reading Frames; Plasmids; United Kingdom | 2009 |
Nosocomial spread of colistin-only-sensitive sequence type 235 Pseudomonas aeruginosa isolates producing the extended-spectrum beta-lactamases GES-1 and GES-5 in Spain.
Topics: Anti-Bacterial Agents; Base Sequence; beta-Lactamases; Colistin; Cross Infection; Humans; Molecular Sequence Data; Pseudomonas aeruginosa | 2009 |
Molecular epidemiology and mechanisms of carbapenem resistance in Pseudomonas aeruginosa.
Topics: Bacterial Proteins; beta-Lactamases; Carbapenems; Drug Resistance, Bacterial; Porins; Pseudomonas aeruginosa | 2009 |
Nonclonal emergence of colistin-resistant Klebsiella pneumoniae isolates from blood samples in South Korea.
Topics: Anti-Bacterial Agents; Bacteremia; Colistin; Cross Infection; Drug Resistance, Bacterial; Humans; Klebsiella Infections; Klebsiella pneumoniae; Microbial Sensitivity Tests; Population Surveillance; Republic of Korea | 2010 |
Characterization of a new metallo-beta-lactamase gene, bla(NDM-1), and a novel erythromycin esterase gene carried on a unique genetic structure in Klebsiella pneumoniae sequence type 14 from India.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; beta-Lactamases; Carboxylic Ester Hydrolases; Cefotaxime; Cefuroxime; Cephalosporins; Cephalothin; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Humans; India; Kinetics; Klebsiella Infections; Klebsiella pneumoniae; Microbial Sensitivity Tests; Molecular Sequence Data; Penicillins; Sequence Analysis, DNA; Sequence Homology, Amino Acid | 2009 |
Detection of the novel extended-spectrum beta-lactamase OXA-161 from a plasmid-located integron in Pseudomonas aeruginosa clinical isolates from Spain.
Topics: Amikacin; Aminoglycosides; Anti-Bacterial Agents; beta-Lactamases; Cefepime; Cephalosporins; Clavulanic Acid; Gentamicins; Humans; Imipenem; Integrons; Meropenem; Molecular Sequence Data; Penicillanic Acid; Piperacillin; Plasmids; Pseudomonas aeruginosa; Pseudomonas Infections; Spain; Tazobactam; Thienamycins | 2009 |
OXA-143, a novel carbapenem-hydrolyzing class D beta-lactamase in Acinetobacter baumannii.
Topics: Acinetobacter baumannii; Amino Acid Sequence; Anti-Bacterial Agents; beta-Lactamases; Carbapenems; Drug Resistance, Multiple, Bacterial; Escherichia coli; Imipenem; Meropenem; Molecular Sequence Data; Oxacillin; Penicillins; Polymerase Chain Reaction; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Thienamycins | 2009 |
First isolation of the blaOXA-23 carbapenemase gene from an environmental Acinetobacter baumannii isolate.
Topics: Acinetobacter baumannii; beta-Lactamases; DNA, Bacterial; Escherichia coli; France; Genes, Bacterial; Water Microbiology | 2010 |
Screening and quantification of the expression of antibiotic resistance genes in Acinetobacter baumannii with a microarray.
Topics: Acinetobacter baumannii; Anti-Bacterial Agents; DNA, Bacterial; DNA, Complementary; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Genes, MDR; Metals, Heavy; Microbial Sensitivity Tests; Mutation; Oligonucleotide Array Sequence Analysis; Reproducibility of Results; Reverse Transcriptase Polymerase Chain Reaction; RNA, Bacterial | 2010 |
Molecular and biochemical characterization of the natural chromosome-encoded class A beta-lactamase from Pseudomonas luteola.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; beta-Lactamases; Catheters, Indwelling; Chromosomes, Bacterial; Cloning, Molecular; Electrophoresis, Gel, Pulsed-Field; Genes, Bacterial; Genetic Variation; Isoelectric Focusing; Kinetics; Microbial Sensitivity Tests; Molecular Sequence Data; Phylogeny; Plasmids; Pseudomonas; Pseudomonas Infections; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Substrate Specificity | 2010 |
BEL-2, an extended-spectrum beta-lactamase with increased activity toward expanded-spectrum cephalosporins in Pseudomonas aeruginosa.
Topics: Belgium; beta-Lactamases; Cephalosporinase; Cephalosporins; Cross Infection; Escherichia coli; Genes, Bacterial; Humans; Kinetics; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections | 2010 |
Novel ambler class A carbapenem-hydrolyzing beta-lactamase from a Pseudomonas fluorescens isolate from the Seine River, Paris, France.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Blotting, Southern; Cloning, Molecular; DNA, Bacterial; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; France; Fresh Water; Gram-Negative Bacteria; Health Surveys; Kinetics; Microbial Sensitivity Tests; Molecular Sequence Data; Plasmids; Pseudomonas fluorescens; Water Microbiology | 2010 |
Novel VIM metallo-beta-lactamase variant from clinical isolates of Enterobacteriaceae from Algeria.
Topics: Algeria; Anti-Bacterial Agents; Base Sequence; beta-Lactamases; beta-Lactams; Carbapenems; DNA, Bacterial; Drug Resistance, Bacterial; Enterobacteriaceae; Enterobacteriaceae Infections; Genome, Bacterial; Hospitals, Military; Imipenem; Isoelectric Focusing; Kinetics; Microbial Sensitivity Tests; Molecular Sequence Data; Penicillins; Phenotype | 2010 |
VIM-19, a metallo-beta-lactamase with increased carbapenemase activity from Escherichia coli and Klebsiella pneumoniae.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Cloning, Molecular; DNA, Bacterial; Escherichia coli; Isoelectric Focusing; Kinetics; Klebsiella pneumoniae; Microbial Sensitivity Tests; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Plasmids; Protein Conformation; Reverse Transcriptase Polymerase Chain Reaction | 2010 |
Activity of a new antipseudomonal cephalosporin, CXA-101 (FR264205), against carbapenem-resistant and multidrug-resistant Pseudomonas aeruginosa clinical strains.
Topics: Anti-Bacterial Agents; beta-Lactamases; Carbapenems; Cephalosporins; Drug Resistance, Multiple, Bacterial; Humans; Isoelectric Focusing; Microbial Sensitivity Tests; Polymerase Chain Reaction; Pseudomonas aeruginosa; Pseudomonas Infections | 2010 |
Acinetobacter baumannii increases tolerance to antibiotics in response to monovalent cations.
Topics: Acinetobacter baumannii; Anti-Bacterial Agents; Bacterial Proteins; Cations, Monovalent; Culture Media; Drug Resistance, Bacterial; Gene Expression Profiling; Gene Expression Regulation, Bacterial; Humans; Microbial Sensitivity Tests; Oligonucleotide Array Sequence Analysis; Proteomics; Sodium Chloride; Virulence Factors | 2010 |
GES-13, a beta-lactamase variant possessing Lys-104 and Asn-170 in Pseudomonas aeruginosa.
Topics: Anti-Bacterial Agents; Aztreonam; beta-Lactamases; beta-Lactams; Cephalosporins; Genetic Variation; Humans; Integrons; Microbial Sensitivity Tests; Molecular Sequence Data; Pseudomonas aeruginosa; Pseudomonas Infections; Sequence Analysis, DNA | 2010 |
Spread of OXA-48-encoding plasmid in Turkey and beyond.
Topics: Anti-Bacterial Agents; Belgium; beta-Lactam Resistance; beta-Lactamases; Carbapenems; DNA Transposable Elements; Egypt; Enterobacteriaceae; Enterobacteriaceae Infections; France; Humans; Lebanon; Microbial Sensitivity Tests; Plasmids; Turkey | 2010 |
Activity of a new cephalosporin, CXA-101 (FR264205), against beta-lactam-resistant Pseudomonas aeruginosa mutants selected in vitro and after antipseudomonal treatment of intensive care unit patients.
Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactam Resistance; beta-Lactamases; Cephalosporins; Cross Infection; Humans; Intensive Care Units; Microbial Sensitivity Tests; Mutation; Pseudomonas aeruginosa; Pseudomonas Infections | 2010 |
Genetic and biochemical characterization of TRU-1, the endogenous class C beta-lactamase from Aeromonas enteropelogenes.
Topics: Aeromonas; Amino Acid Sequence; Base Sequence; beta-Lactamases; Cloning, Molecular; DNA Primers; DNA, Bacterial; Drug Resistance, Bacterial; Escherichia coli; Genes, Bacterial; Humans; Kinetics; Molecular Sequence Data; Phylogeny; Sequence Homology, Amino Acid; Sequence Homology, Nucleic Acid; Transformation, Genetic | 2010 |
PER-6, an extended-spectrum beta-lactamase from Aeromonas allosaccharophila.
Topics: Aeromonas; Animals; Base Sequence; beta-Lactamases; DNA Primers; DNA, Bacterial; Genes, Bacterial; Humans; Kinetics; Microbial Sensitivity Tests; Molecular Sequence Data; Paris; Water Microbiology | 2010 |
Efflux pumps, OprD porin, AmpC beta-lactamase, and multiresistance in Pseudomonas aeruginosa isolates from cystic fibrosis patients.
Topics: Bacterial Outer Membrane Proteins; Bacterial Proteins; beta-Lactamases; Cystic Fibrosis; Drug Resistance, Bacterial; Drug Resistance, Multiple; Electrophoresis, Gel, Pulsed-Field; Humans; Membrane Transport Proteins; Mutation; Porins; Pseudomonas aeruginosa; Pseudomonas Infections; Reverse Transcriptase Polymerase Chain Reaction; Up-Regulation | 2010 |
Biochemical study of a new inhibitor-resistant beta-lactamase, SHV-84, produced by a clinical Escherichia coli strain.
Topics: beta-Lactam Resistance; beta-Lactamases; Escherichia coli; Escherichia coli Proteins; Molecular Sequence Data | 2010 |
KPC-producing extreme drug-resistant Klebsiella pneumoniae isolate from a patient with diabetes mellitus and chronic renal failure on hemodialysis in South Korea.
Topics: Aged; beta-Lactamases; Diabetic Nephropathies; Humans; Kidney Failure, Chronic; Klebsiella Infections; Klebsiella pneumoniae; Male; Renal Dialysis; Republic of Korea | 2010 |
Carbapenem-resistant KPC-2-producing Escherichia coli in a Tel Aviv Medical Center, 2005 to 2008.
Topics: Academic Medical Centers; Bacterial Proteins; Base Sequence; beta-Lactamases; Carbapenems; DNA Primers; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Escherichia coli; Escherichia coli Infections; Humans; In Vitro Techniques; Israel; Microbial Sensitivity Tests; Molecular Epidemiology; Plasmids; Time Factors | 2010 |
In vitro properties of BAL30072, a novel siderophore sulfactam with activity against multiresistant gram-negative bacilli.
Topics: Acinetobacter; Anti-Bacterial Agents; beta-Lactams; Drug Resistance, Multiple, Bacterial; Enterobacteriaceae; Escherichia coli; Escherichia coli Proteins; Gram-Negative Bacteria; Humans; Microbial Sensitivity Tests; Monobactams; Mutation; Penicillin-Binding Proteins; Phenotype; Pseudomonas aeruginosa; Siderophores; Thiazoles | 2010 |
Characterization of CSP-1, a novel extended-spectrum beta-lactamase produced by a clinical isolate of Capnocytophaga sputigena.
Topics: Amino Acid Sequence; Amoxicillin; Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamases; Capnocytophaga; Cephalosporins; Gram-Negative Bacterial Infections; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Sepsis | 2010 |
Characterization of DIM-1, an integron-encoded metallo-beta-lactamase from a Pseudomonas stutzeri clinical isolate in the Netherlands.
Topics: Amino Acid Sequence; Bacterial Proteins; Base Sequence; beta-Lactamases; Cloning, Molecular; DNA, Bacterial; Drug Resistance, Bacterial; Genes, Bacterial; Humans; Integrons; Middle Aged; Molecular Sequence Data; Netherlands; Pseudomonas Infections; Pseudomonas stutzeri; Sequence Homology, Amino Acid; Substrate Specificity | 2010 |
Molecular epidemiology, sequence types, and plasmid analyses of KPC-producing Klebsiella pneumoniae strains in Israel.
Topics: Bacterial Proteins; beta-Lactamases; Carbapenems; Drug Resistance, Bacterial; Humans; Israel; Klebsiella Infections; Klebsiella pneumoniae; Microbial Sensitivity Tests; Molecular Epidemiology; Phylogeny; Plasmids; Polymerase Chain Reaction | 2010 |
Molecular characterization of beta-lactamase genes and their genetic structures in Acinetobacter genospecies 3 isolates in Taiwan.
Topics: Acinetobacter; Acinetobacter Infections; beta-Lactam Resistance; beta-Lactamases; Cephalosporinase; Gene Transfer, Horizontal; Genes, Bacterial; Humans; In Vitro Techniques; Integrons; Microbial Sensitivity Tests; Molecular Epidemiology; Molecular Sequence Data; Phylogeny; Taiwan | 2010 |
Antimicrobial activity of a halocidin-derived peptide resistant to attacks by proteases.
Topics: Chymotrypsin; Humans; Matrix Metalloproteinase 7; Peptides; Pseudomonas aeruginosa; Staphylococcus aureus; Trypsin | 2010 |
Novel chromosome-encoded CTX-M-78 beta-lactamase from a Kluyvera georgiana clinical isolate as a putative origin of CTX-M-25 subgroup.
Topics: Ampicillin; Anti-Bacterial Agents; beta-Lactamases; Chromosomes, Bacterial; Gentamicins; Humans; Kluyvera; Male; Microbial Sensitivity Tests; Middle Aged; Nalidixic Acid; Sulfamethoxazole; Trimethoprim | 2010 |
First survey of metallo-beta-lactamases in clinical isolates of Pseudomonas aeruginosa in a German university hospital.
Topics: Anti-Bacterial Agents; beta-Lactamases; Ceftazidime; Drug Resistance, Bacterial; Germany; Hospitals, University; Humans; Imipenem; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections | 2010 |
Mutational analysis of VIM-2 reveals an essential determinant for metallo-beta-lactamase stability and folding.
Topics: Ampicillin; Ampicillin Resistance; Anti-Bacterial Agents; beta-Lactamases; DNA Mutational Analysis; Enzyme Stability; Escherichia coli; Kinetics; Microbial Sensitivity Tests; Models, Molecular; Protein Conformation; Protein Folding; Structure-Activity Relationship | 2010 |
Extended-spectrum cephalosporinase in Acinetobacter baumannii.
Topics: Acinetobacter baumannii; Amino Acid Sequence; Amino Acid Substitution; Anti-Bacterial Agents; Aztreonam; Bacterial Proteins; beta-Lactamases; Cefepime; Ceftazidime; Cephalosporin Resistance; Cephalosporinase; Cephalosporins; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Monobactams; Mutagenesis, Site-Directed | 2010 |
Nationwide investigation of extended-spectrum beta-lactamases, metallo-beta-lactamases, and extended-spectrum oxacillinases produced by ceftazidime-resistant Pseudomonas aeruginosa strains in France.
Topics: Anti-Bacterial Agents; beta-Lactamases; Ceftazidime; Cephalosporin Resistance; France; Humans; Microbial Sensitivity Tests; Prevalence; Pseudomonas aeruginosa; Pseudomonas Infections | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Acquisition of a transposon encoding extended-spectrum beta-lactamase SHV-12 by Pseudomonas aeruginosa isolates during the clinical course of a burn patient.
Topics: Adult; beta-Lactamases; Burns; DNA Transposable Elements; Female; Humans; Microbial Sensitivity Tests; Polymerase Chain Reaction; Pseudomonas aeruginosa | 2010 |
NagZ inactivation prevents and reverts beta-lactam resistance, driven by AmpD and PBP 4 mutations, in Pseudomonas aeruginosa.
Topics: Bacterial Proteins; beta-Lactam Resistance; beta-Lactams; Ceftazidime; Microbial Sensitivity Tests; Mutation; N-Acetylmuramoyl-L-alanine Amidase; Pseudomonas aeruginosa; Reverse Transcriptase Polymerase Chain Reaction | 2010 |
An ertapenem-resistant extended-spectrum-beta-lactamase-producing Klebsiella pneumoniae clone carries a novel OmpK36 porin variant.
Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; beta-Lactams; Electrophoresis, Polyacrylamide Gel; Ertapenem; Imipenem; Klebsiella pneumoniae; Meropenem; Molecular Sequence Data; Porins; Thienamycins | 2010 |
Comparative biochemical and computational study of the role of naturally occurring mutations at Ambler positions 104 and 170 in GES β-lactamases.
Topics: Ampicillin; beta-Lactamases; Computational Biology; Escherichia coli; Hydrogen Bonding; Microbial Sensitivity Tests; Mutagenesis, Site-Directed; Protein Structure, Secondary; Ticarcillin | 2010 |
Antimicrobial resistance testing of verocytotoxin-producing Escherichia coli and first description of TEM-52 extended-spectrum β-lactamase in serogroup O26.
Topics: Adhesins, Bacterial; Anti-Bacterial Agents; beta-Lactamases; Drug Resistance, Multiple, Bacterial; Escherichia coli; Escherichia coli Proteins; Humans; Plasmids; Shiga Toxins | 2010 |
Emergence of metallo-β-lactamase NDM-1-producing multidrug-resistant Escherichia coli in Australia.
Topics: Anti-Bacterial Agents; Australia; beta-Lactamases; beta-Lactams; Drug Resistance, Multiple, Bacterial; Escherichia coli; Escherichia coli Proteins; Methyltransferases; Microbial Sensitivity Tests; Polymerase Chain Reaction | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Outbreak of meropenem-resistant Serratia marcescens comediated by chromosomal AmpC beta-lactamase overproduction and outer membrane protein loss.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Bacterial Outer Membrane Proteins; Bacterial Proteins; beta-Lactamases; Blotting, Southern; Drug Resistance, Bacterial; Female; Humans; Male; Meropenem; Microbial Sensitivity Tests; Middle Aged; Molecular Sequence Data; Polymerase Chain Reaction; Porins; Reverse Transcriptase Polymerase Chain Reaction; Serratia Infections; Serratia marcescens; Thienamycins; Young Adult | 2010 |
Genetic context and biochemical characterization of the IMP-18 metallo-beta-lactamase identified in a Pseudomonas aeruginosa isolate from the United States.
Topics: Amino Acid Sequence; Bacterial Proteins; beta-Lactamases; beta-Lactams; Ertapenem; Meropenem; Microbial Sensitivity Tests; Models, Genetic; Molecular Sequence Data; Open Reading Frames; Pseudomonas aeruginosa; Sequence Homology, Amino Acid; Thienamycins; United States | 2011 |
Roles of residues Cys69, Asn104, Phe160, Gly232, Ser237, and Asp240 in extended-spectrum beta-lactamase Toho-1.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; beta-Lactamases; Binding Sites; Cefotaxime; Escherichia coli; Microbial Sensitivity Tests; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Sequence Homology, Amino Acid; Structure-Activity Relationship; Substrate Specificity | 2011 |
Potent inhibitors of LpxC for the treatment of Gram-negative infections.
Topics: Amidohydrolases; Animals; Anti-Bacterial Agents; Biphenyl Compounds; Catalytic Domain; Crystallography, X-Ray; Drug Resistance, Bacterial; Hydrogen Bonding; Hydroxamic Acids; Mice; Models, Molecular; Molecular Conformation; Phenyl Ethers; Pseudomonas aeruginosa; Pseudomonas Infections; Rats; Stereoisomerism; Structure-Activity Relationship; Sulfides; Sulfones | 2012 |
Computational analysis of structure-based interactions and ligand properties can predict efflux effects on antibiotics.
Topics: Anti-Bacterial Agents; beta-Lactams; Computational Biology; Drug Resistance, Bacterial; Hydrophobic and Hydrophilic Interactions; Ligands; Membrane Transport Proteins; Microbial Sensitivity Tests; Models, Molecular; Protein Binding; Protein Conformation; Quantitative Structure-Activity Relationship; Regression Analysis; Thermodynamics | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Organic anion transporter 3 interacts selectively with lipophilic β-lactam antibiotics.
Topics: Animals; Anti-Bacterial Agents; beta-Lactams; Biological Transport; Cell Line, Transformed; Humans; Mice; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; Solubility; Structure-Activity Relationship | 2013 |
Optimization of novel monobactams with activity against carbapenem-resistant Enterobacteriaceae - Identification of LYS228.
Topics: Animals; Anti-Bacterial Agents; Aztreonam; Bacterial Proteins; beta-Lactam Resistance; beta-Lactamases; Carbapenem-Resistant Enterobacteriaceae; CHO Cells; Cricetulus; Drug Stability; Escherichia coli; Female; Humans; Meropenem; Mice; Microbial Sensitivity Tests; Molecular Structure; Monobactams; Pseudomonas aeruginosa; Receptors, GABA-A; Seizures; Structure-Activity Relationship; Thienamycins | 2018 |
Microwave-assisted solid-phase synthesis of antisense acpP peptide nucleic acid-peptide conjugates active against colistin- and tigecycline-resistant E. coli and K. pneumoniae.
Topics: Anti-Bacterial Agents; Colistin; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Escherichia coli; Klebsiella pneumoniae; Microbial Sensitivity Tests; Microwaves; Molecular Structure; Peptide Nucleic Acids; Peptides; Solid-Phase Synthesis Techniques; Structure-Activity Relationship; Tigecycline | 2019 |
A γ-Lactam Siderophore Antibiotic Effective against Multidrug-Resistant Gram-Negative Bacilli.
Topics: Animals; Anti-Bacterial Agents; Bacterial Proteins; Binding Sites; Catalytic Domain; Crystallography, X-Ray; Drug Resistance, Multiple, Bacterial; Gram-Negative Bacteria; Half-Life; Lactams; Mice; Microbial Sensitivity Tests; Molecular Docking Simulation; Penicillin-Binding Proteins; Pseudomonas aeruginosa; Siderophores | 2020 |
A γ-lactam siderophore antibiotic effective against multidrug-resistant Pseudomonas aeruginosa, Klebsiella pneumoniae, and Acinetobacter spp.
Topics: Acinetobacter baumannii; Anti-Bacterial Agents; Dose-Response Relationship, Drug; Drug Resistance, Multiple, Bacterial; Klebsiella pneumoniae; Lactams; Microbial Sensitivity Tests; Molecular Structure; Pseudomonas aeruginosa; Siderophores; Structure-Activity Relationship | 2021 |
A novel tricyclic β-lactam exhibiting potent antibacterial activities against carbapenem-resistant Enterobacterales: Synthesis and structure-activity-relationships.
Topics: Anti-Bacterial Agents; beta-Lactams; Carbapenems; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Enterobacteriaceae; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship | 2021 |