azoxymethane has been researched along with sulindac in 25 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 9 (36.00) | 18.2507 |
| 2000's | 8 (32.00) | 29.6817 |
| 2010's | 8 (32.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kelloff, G; Rao, CV; Reddy, BS; Rivenson, A; Simi, B; Steele, V; Zang, E | 1 |
| Reddy, BS; Singh, J | 1 |
| Rao, CV; Reddy, BS; Seibert, K | 1 |
| Kelloff, GJ; Rao, CV; Reddy, BS; Samaha, HS; Steele, V | 1 |
| Ahnen, DJ; Alberts, DS; Bogert, C; Brendel, K; Burt, RW; Ellsworth, L; Finn, T; Gross, PH; Guillen, JM; Hixson, LJ; Li, H; Pamukcu, R; Paranka, NS; Piazza, GA; Ritchie, J; Sperl, G | 1 |
| Newmark, HL; Rao, CV; Reddy, BS | 1 |
| Kawamori, T; Kelloff, GJ; Lubet, RA; Rao, CV; Reddy, BS; Steele, VE | 1 |
| Kawamori, T; Kelloff, G; Lubet, R; Rao, CV; Reddy, BS; Steele, V | 1 |
| Agarwal, B; Bhendwal, S; Holt, PR; Ramey, WR; Rao, CV; Reddy, BS; Shirin, H | 1 |
| Hasegawa, J; Jinnai, T; Kawasaki, H; Kishimoto, Y; Morisawa, T; Shiota, G; Takata, N | 1 |
| Hara, Y; Hasegawa, J; Isemura, M; Kishimoto, Y; Kohri, T; Miura, N; Ohishi, T; Shiota, G | 1 |
| Hara, A; Hirose, Y; Katayama, M; Kuno, T; Mori, H; Saji, S; Sakata, K; Yamada, Y | 1 |
| Hasegawa, J; Idobe-Fujii, Y; Kishimoto, Y; Marumoto, A; Miura, N; Morisawa, T; Murawaki, Y; Ohishi, T; Sano, A; Shiota, G; Yashima, K | 1 |
| Anzai, H; Chiba, T; Orii, S; Saito, S; Suzuki, K; Yamaguchi, T | 1 |
| Hu, Y; Le Leu, RK; Young, GP | 2 |
| Koetsier, JL; Kunte, DP; Roy, HK; Wali, RK | 1 |
| Hu, Y; Le Leu, RK; Martin, JE; Young, GP | 2 |
| Bean, E; Currey, N; Dahlstrom, JE; Daniel, JJ; Gupta, R; Kohonen-Corish, MR; Mladenova, D; Musgrove, EA; Pickford, R | 1 |
| DeCastro, A; Janakiram, NB; Lee, HJ; Paul, S; Rao, CV; Reddy, BS; Simi, B; Smolarek, AK; So, JY; Steele, V; Suh, N; Wang, CX | 1 |
| Barnholtz-Sloan, JS; Chen, Y; Dawson, DM; Fink, SP; Kopelovich, L; Kresak, A; Lawrence, EG; Markowitz, SD; Willis, JE; Yang, P; Zhang, Y | 1 |
| Agarwal, R; Charepalli, V; Radhakrishnan, S; Reddivari, L; Vadde, R; Vanamala, JK | 1 |
| Barton, JK; Chandra, S; Gerner, EW; Nymeyer, AC; Rice, PF | 1 |
| Currey, N; Dahlstrom, JE; Daniel, JJ; Kohonen-Corish, MRJ; Mladenova, DN | 1 |
25 other study(ies) available for azoxymethane and sulindac
| Article | Year |
|---|---|
Chemoprevention of colon carcinogenesis by sulindac, a nonsteroidal anti-inflammatory agent.
Topics: Adenocarcinoma; Animals; Azoxymethane; Colonic Neoplasms; Drug Screening Assays, Antitumor; Hydroxyeicosatetraenoic Acids; Male; Pharmaceutical Vehicles; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Diacylglycerol-Lyase; Phosphatidylinositol Phosphates; Phosphoinositide Phospholipase C; Phospholipases A; Phospholipases A2; Phosphoric Diester Hydrolases; Prostaglandins; Rats; Rats, Inbred F344; Sulindac; Thromboxanes | 1995 |
Molecular markers in chemoprevention of colon cancer. Inhibition of expression of ras-p21 and p53 by sulindac during azoxymethane-induced colon carcinogenesis.
Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Biomarkers, Tumor; Blotting, Western; Carcinogens; Colon; Colonic Neoplasms; Intestinal Mucosa; Male; Proto-Oncogene Proteins p21(ras); Rats; Rats, Inbred F344; Sulindac; Tumor Suppressor Protein p53 | 1995 |
Evaluation of cyclooxygenase-2 inhibitor for potential chemopreventive properties in colon carcinogenesis.
Topics: Animals; Azoxymethane; Carcinogens; Colon; Colonic Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Double-Blind Method; Drug Screening Assays, Antitumor; Isoenzymes; Male; Precancerous Conditions; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred F344; Rats, Inbred Lew; Sulindac | 1996 |
Modulation of apoptosis by sulindac, curcumin, phenylethyl-3-methylcaffeate, and 6-phenylhexyl isothiocyanate: apoptotic index as a biomarker in colon cancer chemoprevention and promotion.
Topics: Adenocarcinoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Apoptosis; Azoxymethane; Biomarkers, Tumor; Caffeic Acids; Carcinogens; Colonic Neoplasms; Curcumin; Isothiocyanates; Male; Rats; Rats, Inbred F344; Sulindac | 1997 |
Sulindac sulfone inhibits azoxymethane-induced colon carcinogenesis in rats without reducing prostaglandin levels.
Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Carcinogens; Colonic Neoplasms; Dinoprostone; Male; Rats; Rats, Inbred F344; Sulindac | 1997 |
Chemopreventive effect of squalene on colon cancer.
Topics: Animals; Azoxymethane; Body Weight; Colonic Neoplasms; Male; Precancerous Conditions; Rats; Rats, Inbred F344; Squalene; Sulindac | 1998 |
Chemopreventive efficacy of sulindac sulfone against colon cancer depends on time of administration during carcinogenic process.
Topics: Adenocarcinoma; Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Apoptosis; Azoxymethane; Carcinogens; Cell Transformation, Neoplastic; Colonic Neoplasms; Cyclooxygenase Inhibitors; Disease Progression; Dose-Response Relationship, Drug; Drug Administration Schedule; Male; Neoplasm Invasiveness; Rats; Rats, Inbred F344; Sulindac; Weight Gain | 1999 |
Chemopreventive effect of S-methylmethane thiosulfonate and sulindac administered together during the promotion/progression stages of colon carcinogenesis.
Topics: Adenocarcinoma; Adenoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Alkylating; Azoxymethane; Carcinogens; Colonic Neoplasms; Drug Screening Assays, Antitumor; Drug Therapy, Combination; Male; Methyl Methanesulfonate; Rats; Rats, Inbred F344; Sulindac | 1999 |
Lovastatin augments sulindac-induced apoptosis in colon cancer cells and potentiates chemopreventive effects of sulindac.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Apoptosis; Azoxymethane; Carcinogens; Colon; Colonic Neoplasms; Cyclooxygenase Inhibitors; Drug Synergism; Isoenzymes; Lovastatin; Male; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred F344; Sulindac; Tumor Cells, Cultured | 1999 |
Sulindac and a cyclooxygenase-2 inhibitor, etodolac, increase APC mRNA in the colon of rats treated with azoxymethane.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Azoxymethane; Blotting, Northern; Carcinogens; Colon; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Etodolac; Gene Expression; Genes, APC; Intestinal Mucosa; Isoenzymes; Male; Membrane Proteins; Polymerase Chain Reaction; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred F344; RNA, Messenger; Sulindac | 2000 |
Synergistic effects of (-)-epigallocatechin gallate with sulindac against colon carcinogenesis of rats treated with azoxymethane.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Azoxymethane; Carcinogens; Catechin; Choristoma; Colon; Colonic Neoplasms; Drug Synergism; In Situ Nick-End Labeling; Incidence; Male; Nucleolus Organizer Region; Precancerous Conditions; Rats; Rats, Inbred F344; Sulindac; Tea | 2002 |
Induction of apoptosis by sulindac in azoxymethane-induced possible colonic premalignant lesions in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Apoptosis; Azoxymethane; beta Catenin; Carcinogens; Cell Division; Cell Nucleus; Colonic Neoplasms; Cytoskeletal Proteins; Diet; In Situ Nick-End Labeling; Incidence; Male; Nucleolus Organizer Region; Precancerous Conditions; Rats; Rats, Inbred F344; Silver; Sulindac; Trans-Activators | 2002 |
Effects of long-term administration of sulindac on APC mRNA and apoptosis in colons of rats treated with azoxymethane.
Topics: Adenomatous Polyposis Coli Protein; Animals; Apoptosis; Azoxymethane; Colon; Colonic Neoplasms; Cyclooxygenase Inhibitors; In Situ Nick-End Labeling; Intestinal Mucosa; Male; Nucleolus Organizer Region; Precancerous Conditions; Rats; Rats, Inbred F344; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulindac | 2002 |
Chemoprevention for colorectal tumorigenesis associated with chronic colitis in mice via apoptosis.
Topics: Animals; Apoptosis; Azoxymethane; Carcinogens; Chemoprevention; Chronic Disease; Colitis; Colon; Colonic Neoplasms; Colorectal Neoplasms; Cyclooxygenase Inhibitors; Intestinal Mucosa; Male; Mice; Mice, Inbred CBA; Sulindac; Water Supply | 2003 |
Sulindac corrects defective apoptosis and suppresses azoxymethane-induced colonic oncogenesis in p53 knockout mice.
Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents; Apoptosis; Azoxymethane; Colonic Neoplasms; Mice; Mice, Inbred C57BL; Mice, Knockout; Sulindac; Tumor Suppressor Protein p53 | 2005 |
Defective acute apoptotic response to genotoxic carcinogen in small intestine of APC(Min/+) mice is restored by sulindac.
Topics: Animals; Antineoplastic Agents; Apoptosis; Azoxymethane; Carcinogens; Cell Proliferation; Colon; Female; Genes, APC; Intestine, Small; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Polymerase Chain Reaction; Sulindac | 2007 |
Antiproliferative effect of sulindac in colonic neoplasia prevention: role of COOH-terminal Src kinase.
Topics: Animals; Antineoplastic Agents; Azoxymethane; Cell Cycle; Cell Proliferation; Colon; Colonic Neoplasms; CSK Tyrosine-Protein Kinase; Cyclin-Dependent Kinase Inhibitor p21; Down-Regulation; Drug Screening Assays, Antitumor; Enzyme Induction; HT29 Cells; Humans; Male; Models, Biological; Protein-Tyrosine Kinases; Rats; Rats, Inbred F344; src-Family Kinases; Sulindac | 2008 |
R-flurbiprofen suppresses distal nonmucin-producing colorectal tumors in azoxymethane-treated rats, without suppressing eicosanoid production.
Topics: Animals; Antineoplastic Agents; Azoxymethane; Carcinogens; Colorectal Neoplasms; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Eicosanoids; Flurbiprofen; Male; Mucins; Rats; Rats, Sprague-Dawley; Sulindac | 2010 |
The NSAID sulindac is chemopreventive in the mouse distal colon but carcinogenic in the proximal colon.
Topics: Adenocarcinoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Apoptosis; Azoxymethane; Carcinogens; Cell Transformation, Neoplastic; Colon; Colonic Neoplasms; Drug Evaluation, Preclinical; Gene Expression Regulation; Hypoxia-Inducible Factor 1, alpha Subunit; Inflammation Mediators; Intestinal Mucosa; Mice; Mice, Inbred C57BL; Mice, Knockout; MutS Homolog 2 Protein; Precancerous Conditions; Sulindac; Tumor Suppressor Protein p53 | 2011 |
Combination of atorvastatin with sulindac or naproxen profoundly inhibits colonic adenocarcinomas by suppressing the p65/β-catenin/cyclin D1 signaling pathway in rats.
Topics: Adenocarcinoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticholesteremic Agents; Antineoplastic Combined Chemotherapy Protocols; Atorvastatin; Azoxymethane; beta Catenin; Carcinogens; Colonic Neoplasms; Cyclin D1; eIF-2 Kinase; Enzyme-Linked Immunosorbent Assay; Heptanoic Acids; Immunoenzyme Techniques; Interleukin-4; Male; Naproxen; Nitric Oxide Synthase Type II; Pyrroles; Rats; Rats, Inbred F344; Signal Transduction; Sulindac; Tumor Necrosis Factor-alpha | 2011 |
Comparing the effects of COX and non-COX-inhibiting NSAIDs on enhancement of apoptosis and inhibition of aberrant crypt foci formation in a rat colorectal cancer model.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Azoxymethane; Colorectal Neoplasms; Cyclooxygenase Inhibitors; Disease Models, Animal; Flurbiprofen; Male; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Sulindac | 2013 |
Sulindac reversal of 15-PGDH-mediated resistance to colon tumor chemoprevention with NSAIDs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Aspirin; Azoxymethane; Carcinogens; Celecoxib; Chemoprevention; Colonic Neoplasms; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Hydroxyprostaglandin Dehydrogenases; Inflammation; Intestinal Mucosa; Membrane Proteins; Mice; Mice, Knockout; Pyrazoles; Sulfonamides; Sulindac | 2015 |
Anthocyanin-containing purple-fleshed potatoes suppress colon tumorigenesis via elimination of colon cancer stem cells.
Topics: Animals; Anthocyanins; Antineoplastic Agents; Apoptosis; Azoxymethane; bcl-2-Associated X Protein; beta Catenin; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Colonic Neoplasms; Cytochromes c; Food; Humans; In Situ Nick-End Labeling; Lentivirus; Male; Mice; Mitochondria; Neoplastic Stem Cells; RNA, Small Interfering; Solanum tuberosum; Sulindac; Tumor Suppressor Protein p53; Wnt Proteins | 2015 |
Intermittent Dosing with Sulindac Provides Effective Colorectal Cancer Chemoprevention in the Azoxymethane-Treated Mouse Model.
Topics: Animals; Antineoplastic Agents; Azoxymethane; Carcinogens; Chemoprevention; Colorectal Neoplasms; Disease Models, Animal; Female; Mice; Sulindac | 2017 |
Microsatellite Instability in Mouse Models of Colorectal Cancer.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Azoxymethane; Colon; Colonic Neoplasms; Disease Models, Animal; Mice; Mice, Knockout; Microsatellite Instability; Microsatellite Repeats; MutS Homolog 2 Protein; Sulindac; Tumor Suppressor Protein p53 | 2018 |