Page last updated: 2024-08-23

azoxymethane and methylazoxymethanol acetate

azoxymethane has been researched along with methylazoxymethanol acetate in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19906 (46.15)18.7374
1990's5 (38.46)18.2507
2000's2 (15.38)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Miyazawa, T; Moriya, M; Ohta, T; Shirasu, Y; Sugiyama, F1
Christiansen, G; Fiala, ES; Kulakis, C; Weisburger, JH1
Fiala, E1
Fiala, ES; Ishizaki, H; Sohn, OS; Yang, CS1
el-Bayoumy, K; Fiala, ES; Joseph, C; Reddy, BS; Sohn, OS1
Glickman, BW; Horsfall, MJ; Mohn, GR; van Helten, JB; Zeilmaker, MJ1
Centra, MM; McMahon, TF; Peggins, JO; Weiner, M1
Fiala, ES; Hamilton, SR; Puz, C; Sohn, OS; Williams, GM1
Johnston, JB; Kari, FW; Truex, CR; Visek, WJ1
Bennink, MR; Glauert, HP1
Inagake, M; Iwashima, A; Kikuoka, N; Kitao, Y; Matsumoto, H; Nakatani, H; Nishimura, H; Oya, K; Takahashi, T; Yamane, T1
Fiala, ES; Gonzalez, FJ; Requeijo, SP; Sohn, OS; Weisburger, JH1
Chen, J; Huang, XF1

Reviews

1 review(s) available for azoxymethane and methylazoxymethanol acetate

ArticleYear
The signal pathways in azoxymethane-induced colon cancer and preventive implications.
    Cancer biology & therapy, 2009, Volume: 8, Issue:14

    Topics: Adenocarcinoma; Adenoma; Adiponectin; Animals; Anticarcinogenic Agents; Apoptosis; Azoxymethane; Carcinogens; Colonic Neoplasms; Cytochrome P-450 CYP2E1; Diet; DNA Damage; Genes, ras; Humans; MAP Kinase Signaling System; Methylazoxymethanol Acetate; Mice; Mice, Knockout; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Signal Transduction; Transforming Growth Factor beta; Transforming Growth Factor beta2

2009

Other Studies

12 other study(ies) available for azoxymethane and methylazoxymethanol acetate

ArticleYear
Assay for mutagenicity of bile in Sprague-Dawley rats treated subcutaneously with intestinal carcinogens.
    Journal of the National Cancer Institute, 1979, Volume: 63, Issue:4

    Topics: Animals; Azoxymethane; Bile; Carcinogens; Dimethylhydrazines; Drug Evaluation, Preclinical; Glucuronidase; In Vitro Techniques; Injections, Subcutaneous; Male; Methylazoxymethanol Acetate; Microsomes, Liver; Mutagens; Rats; Salmonella typhimurium

1979
Inhibition of the metabolism of the colon carcinogen, azoxymethane, by pyrazole.
    Cancer research, 1978, Volume: 38, Issue:12

    Topics: Animals; Azo Compounds; Azoxymethane; Biotransformation; Carbon Dioxide; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Methylazoxymethanol Acetate; Microsomes, Liver; Pyrazoles; Rats; Rats, Inbred F344

1978
Investigations into the metabolism and mode of action of the colon carcinogen 1, 2-dimethylhydrazine.
    Cancer, 1975, Volume: 36, Issue:6 Suppl

    Topics: Animals; Azo Compounds; Azoxymethane; Chromatography, Gel; Chromatography, Thin Layer; Colonic Neoplasms; Dimethylhydrazines; Hydrazines; Methane; Methylazoxymethanol Acetate; Neoplasms, Experimental

1975
Metabolism of azoxymethane, methylazoxymethanol and N-nitrosodimethylamine by cytochrome P450IIE1.
    Carcinogenesis, 1991, Volume: 12, Issue:1

    Topics: Acetone; Animals; Azoxymethane; Carcinogens; Cytochrome P-450 Enzyme System; Dimethylnitrosamine; Isoenzymes; Male; Methylazoxymethanol Acetate; Microsomes, Liver; Rats; Rats, Inbred Strains

1991
Mechanism of benzylselenocyanate inhibition of azoxymethane-induced colon carcinogenesis in F344 rats.
    Cancer research, 1991, Jun-01, Volume: 51, Issue:11

    Topics: Animals; Azoxymethane; Body Weight; Colonic Neoplasms; Cyanates; Cytochrome P-450 Enzyme System; DNA; Drug Screening Assays, Antitumor; Guanine; Male; Methylation; Methylazoxymethanol Acetate; Microsomes, Liver; Organoselenium Compounds; Rats; Rats, Inbred F344; Selenium

1991
Mutational specificities of environmental carcinogens in the lacl gene of Escherichia coli H. V: DNA sequence analysis of mutations in bacteria recovered from the liver of Swiss mice exposed to 1,2-dimethylhydrazine, azoxymethane, and methylazoxymethanola
    Molecular carcinogenesis, 1991, Volume: 4, Issue:3

    Topics: 1,2-Dimethylhydrazine; Alkylating Agents; Animals; Azoxymethane; Base Sequence; Carcinogens, Environmental; Dimethylhydrazines; DNA Mutational Analysis; DNA, Bacterial; Drug Resistance, Microbial; Escherichia coli; Genes, Bacterial; Liver; Methylazoxymethanol Acetate; Mice; Mice, Inbred Strains; Molecular Sequence Data

1991
Age-related changes in biotransformation of azoxymethane and methylazoxymethanol in vitro.
    Xenobiotica; the fate of foreign compounds in biological systems, 1990, Volume: 20, Issue:5

    Topics: Aging; Alcohol Dehydrogenase; Animals; Azo Compounds; Azoxymethane; Biotransformation; Carcinogens; Colon; Cytochrome P-450 Enzyme System; Glucuronates; Glucuronosyltransferase; Hydroxylation; Hymecromone; Male; Methylazoxymethanol Acetate; Microsomes; Microsomes, Liver; Rats; Rats, Inbred F344

1990
Enhancement of rat liver microsomal metabolism of azoxymethane to methylazoxymethanol by chronic ethanol administration: similarity to the microsomal metabolism of N-nitrosodimethylamine.
    Cancer research, 1987, Jun-15, Volume: 47, Issue:12

    Topics: Animals; Azo Compounds; Azoxymethane; Chromatography, High Pressure Liquid; Dimethylnitrosamine; Enzyme Activation; Ethanol; Kinetics; Male; Methylazoxymethanol Acetate; Microsomes, Liver; Rats; Rats, Inbred F344

1987
Effect of dietary protein concentration on yield of mutagenic metabolites from 1,2-dimethylhydrazine in mice.
    Cancer research, 1983, Volume: 43, Issue:8

    Topics: 1,2-Dimethylhydrazine; Animals; Azo Compounds; Azoxymethane; Biotransformation; Dietary Proteins; Dimethylhydrazines; Methylazoxymethanol Acetate; Methylhydrazines; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mutagenicity Tests; Salmonella typhimurium

1983
Metabolism of 1,2-dimethylhydrazine by cultured rat colon epithelial cells.
    Nutrition and cancer, 1983, Volume: 5, Issue:2

    Topics: Animals; Azoxymethane; Cells, Cultured; Colon; Culture Media; Dimethylhydrazines; Epithelial Cells; Germ-Free Life; In Vitro Techniques; Male; Methylazoxymethanol Acetate; Methylhydrazines; Rats; Rats, Inbred Strains

1983
Inhibition of 1,2-dimethylhydrazine-induced oxidative DNA damage by green tea extract in rat.
    Japanese journal of cancer research : Gann, 1995, Volume: 86, Issue:11

    Topics: 1,2-Dimethylhydrazine; 8-Hydroxy-2'-Deoxyguanosine; Administration, Oral; Animals; Anticarcinogenic Agents; Azoxymethane; Biotransformation; Catechin; Colon; Deoxyguanosine; Diazonium Compounds; Dimethylhydrazines; DNA; DNA Damage; Free Radical Scavengers; Injections, Subcutaneous; Intestinal Mucosa; Kidney; Liver; Male; Methylation; Methylazoxymethanol Acetate; Oxidation-Reduction; Oxidative Stress; Plant Extracts; Rats; Rats, Sprague-Dawley; Tea

1995
Differential effects of CYP2E1 status on the metabolic activation of the colon carcinogens azoxymethane and methylazoxymethanol.
    Cancer research, 2001, Dec-01, Volume: 61, Issue:23

    Topics: Animals; Azoxymethane; Biotransformation; Carcinogens; Colon; Cytochrome P-450 CYP2E1; DNA; DNA Methylation; Female; Guanine; Liver; Male; Methylazoxymethanol Acetate; Mice; Precancerous Conditions

2001