azoxymethane has been researched along with cyclin d1 in 38 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (5.26) | 18.2507 |
| 2000's | 13 (34.21) | 29.6817 |
| 2010's | 17 (44.74) | 24.3611 |
| 2020's | 6 (15.79) | 2.80 |
| Authors | Studies |
|---|---|
| Papanikolaou, A; Rosenberg, DW; Sabourin, CL; Wang, QS | 1 |
| Esumi, H; Fukushima, S; Otori, K; Sugiyama, K | 1 |
| Azuma, Y; Kagami, S; Kohno, H; Murakami, M; Ogawa, H; Shimada, R; Sumida, T; Tanaka, T | 1 |
| Fan, K; Kelloff, GJ; Lamprecht, SA; Leung, D; Lipkin, M; Liu, Y; Newmark, H; Shinozaki, H; Steele, VE; Yang, K | 1 |
| Bissonnette, M; Boss, GR; Brasitus, TA; Hart, J; Khare, S; Nguyen, L; Skarosi, S; Varki, N; von Lintig, FC; Wali, RK; Zhang, Y | 1 |
| Bissonnette, M; Brasitus, T; Cohen, G; Hart, J; Joseph, L; Khare, S; Nguyen, L; Ramaswamy, A; Sitrin, M; Tretiakova, M; Wali, RK; Wang, J; Wen, M | 1 |
| Fujita, K; Iigo, M; Matsuda, E; Sekine, K; Tsuda, H | 1 |
| Hart, J; Karolski, WJ; Ratashak, A; Roy, HK; Smyrk, TC; Wali, RK | 1 |
| Alexander, J; Knutsen, H; Løberg, EM; Paulsen, JE; Ølstørn, HB | 1 |
| Dannenberg, AJ; Dawson, D; Dotson, A; Guda, K; Lawrence, E; Lovgren, AK; Luo, G; Markowitz, SD; Myung, SJ; Newman, RA; Platzer, P; Pretlow, TP; Rerko, RM; Willis, J; Yan, M | 1 |
| Backman, V; Bissonnette, M; Goldberg, M; Hart, J; Kim, YL; Koetsier, JL; Kunte, DP; Liu, Y; Roy, HK; Wali, RK | 1 |
| Bissonnette, M; Cerda, S; Cohen, G; Dougherty, U; Fichera, A; Gong, C; Hart, J; Jagadeeswaran, S; Joseph, L; Khare, S; Little, N; Mustafi, R; Sehdev, A; Tallerico, M; Tretiakova, M; Turner, JR; Yuan, W | 1 |
| Beppu, F; Hosokawa, M; Kohno, H; Miyamoto, S; Miyashita, K; Suzuki, R; Tanaka, T; Yasui, Y | 1 |
| Agarwal, R; Singh, RP; Tyagi, A; Velmurugan, B | 1 |
| Issa, AY; Muga, SJ; Nitcheva, D; Smith, T; Volate, SR; Wargovich, MJ | 1 |
| Caruso, R; Fantini, MC; Fina, D; Macdonald, TT; Monteleone, G; Pallone, F; Palmieri, G; Pellegrini, R; Sarra, M; Stolfi, C | 1 |
| Ashokkumar, P; Sudhandiran, G | 1 |
| DeCastro, AJ; Lee, HJ; Paul, S; Rimando, AM; Simi, B; Smolarek, AK; So, JY; Suh, N; Wang, CX; Zhou, R | 1 |
| Agarwal, C; Agarwal, R; Singh, RP; Velmurugan, B | 1 |
| DeCastro, A; Janakiram, NB; Lee, HJ; Paul, S; Rao, CV; Reddy, BS; Simi, B; Smolarek, AK; So, JY; Steele, V; Suh, N; Wang, CX | 1 |
| Agis-Torres, A; Bravo, L; Gómez-Juaristi, M; Goya, L; López-Oliva, E; Martín, MÁ; Mateos, R; Ramos, S; Rodríguez-Ramiro, I | 1 |
| Chen, YK; Guan, F; Lee, MJ; Li, G; Lin, Y; Liu, AB; Shih, W; Yang, CS; Yang, Z | 1 |
| Chen, H; Li, Q; Zhang, Y; Zhou, D | 1 |
| MacLeod, RJ | 1 |
| Drachenberg, C; Heath, J; Peng, Z; Raufman, JP; Xie, G | 1 |
| Amin, S; Choi, CI; Desai, D; Janakiram, NB; Mohammed, A; Rao, CV; Ravillah, D; Zhang, Y | 1 |
| Colburn, NH; Hou, W; Hua, B; Jia, L; Li, W; Lin, H; Matter, MS; Saud, SM; Young, MR | 1 |
| Choi, MS; Kim, JS; Kim, YJ; Park, JH; Seo, YR; Sung, MK | 1 |
| Fukui, T; Kishimoto, M; Mitsuyama, T; Miyamoto, S; Nishio, A; Okazaki, K; Sakaguchi, Y; Suzuki, R; Takahashi, Y; Takeo, M; Uchida, K | 1 |
| Alam, S; Ansari, KM; Kumar, R; Mir, SS; Pal, A | 1 |
| Badmaev, V; Chou, YC; Ho, CT; Pahwa, M; Pan, MH; Suh, JH; Wang, Y | 1 |
| Jia, W; Luo, Y; Niu, W; Wang, J; Wu, Z; Yang, M; Zhang, H; Zhang, X | 1 |
| Huh, TG; Jeong, BJ; Jeong, JS; Kim, HY; Lee, JS; Park, KY; Song, JL | 1 |
| Hashimoto, S; Kojima, H; Kubota, A; Maeda, H; Miyashita, K; Mutoh, M; Ohta, T; Ono, S; Tanaka, T; Terasaki, M | 1 |
| Chen, Y; Diao, T; Li, D; Shang, G; Shi, L; Sun, L; Yin, X | 1 |
| Chen, W; Jin, X; Liu, B; Wu, P; Xiao, W; Yi, S | 1 |
| Chen, C; El-Nezami, H; Ismaiah, MJ; Leung, HKM; Lo, EKK; Zhang, F | 1 |
| Fukui, T; Honzawa, Y; Horitani, S; Matsumoto, Y; Naganuma, M; Okazaki, K; Suzuki, R; Tahara, T; Tanimura, Y; Tomiyama, T | 1 |
38 other study(ies) available for azoxymethane and cyclin d1
| Article | Year |
|---|---|
Altered expression of cyclin D1 and cyclin-dependent kinase 4 in azoxymethane-induced mouse colon tumorigenesis.
Topics: Animals; Azoxymethane; Carcinogens; Colon; Colonic Neoplasms; Cyclin D1; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinases; Genes, ras; Immunohistochemistry; Male; Mice; Proto-Oncogene Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 1998 |
Expression of the cyclin D1 gene in rat colorectal aberrant crypt foci and tumors induced by azoxymethane.
Topics: Adenocarcinoma; Animals; Azoxymethane; Bromodeoxyuridine; Cell Division; Cell Nucleus; Colorectal Neoplasms; Cyclin D1; Cytoplasm; Gene Expression; Hyperplasia; Intestinal Mucosa; Male; Rats; Rats, Inbred F344; Time Factors | 1999 |
Suppression of azoxymethane-induced colon carcinogenesis in male F344 rats by mandarin juices rich in beta-cryptoxanthin and hesperidin.
Topics: Adenocarcinoma; Adenoma; Animals; Anticarcinogenic Agents; Apoptosis; Azoxymethane; beta Carotene; Beverages; Carcinogens; Citrus; Colonic Neoplasms; Cryptoxanthins; Cyclin D1; Hesperidin; Male; Proliferating Cell Nuclear Antigen; Rats; Rats, Inbred F344; Xanthophylls | 2000 |
Chemoprevention studies of the flavonoids quercetin and rutin in normal and azoxymethane-treated mouse colon.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Azoxymethane; Carcinogens; Cell Division; Colon; Colonic Neoplasms; Cyclin D1; Female; Intestinal Mucosa; Male; Mice; Precancerous Conditions; Quercetin; Rutin | 2000 |
Mutational and nonmutational activation of p21ras in rat colonic azoxymethane-induced tumors: effects on mitogen-activated protein kinase, cyclooxygenase-2, and cyclin D1.
Topics: Animals; Azoxymethane; beta Catenin; Carcinogens; Colonic Neoplasms; Cyclin D1; Cyclooxygenase 2; Cytoskeletal Proteins; Enzyme Activation; Genes, ras; Isoenzymes; Male; Mitogen-Activated Protein Kinase Kinases; Mutation; Polymorphism, Restriction Fragment Length; Prostaglandin-Endoperoxide Synthases; Proto-Oncogene Proteins p21(ras); Rats; Rats, Inbred F344; Trans-Activators | 2000 |
Ursodeoxycholic acid and F(6)-D(3) inhibit aberrant crypt proliferation in the rat azoxymethane model of colon cancer: roles of cyclin D1 and E-cadherin.
Topics: Animals; Azoxymethane; Base Sequence; Biomarkers, Tumor; Biopsy, Needle; Blotting, Western; Cadherins; Cell Division; Cholecalciferol; Colonic Neoplasms; Cyclin D1; Disease Models, Animal; Immunohistochemistry; Injections, Intraperitoneal; Intestinal Mucosa; Male; Molecular Sequence Data; Neoplasms, Experimental; Polymerase Chain Reaction; Random Allocation; Rats; Rats, Inbred F344; Reference Values; RNA, Messenger; Sensitivity and Specificity; Ursodeoxycholic Acid | 2002 |
Lactoferrin modifies apoptosis-related gene expression in the colon of the azoxymethane-treated rat.
Topics: Administration, Oral; Animals; Apoptosis; Azoxymethane; Carcinogens; Cell Transformation, Neoplastic; Chemoprevention; Colonic Neoplasms; Cyclin D1; Disease Models, Animal; Fas Ligand Protein; Gene Expression Regulation; Lactoferrin; Male; Membrane Glycoproteins; Rats; Rats, Inbred F344; Up-Regulation | 2004 |
The nonsteroidal anti-inflammatory drug, nabumetone, differentially inhibits beta-catenin signaling in the MIN mouse and azoxymethane-treated rat models of colon carcinogenesis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Azoxymethane; beta Catenin; Blotting, Western; Butanones; Cadherins; Carcinogens; Colonic Neoplasms; Cyclin D1; Cytoskeletal Proteins; Disease Models, Animal; Glycogen Synthase Kinase 3; Immunohistochemistry; Male; Mice; Nabumetone; Rats; Signal Transduction; Trans-Activators | 2005 |
Identification of flat dysplastic aberrant crypt foci in the colon of azoxymethane-treated A/J mice.
Topics: Animals; Azoxymethane; beta Catenin; Carcinogens; Cell Nucleus; Colonic Neoplasms; Cyclin D1; Female; Hyperplasia; Male; Mice; Mice, Inbred A; Precancerous Conditions | 2006 |
15-Hydroxyprostaglandin dehydrogenase is an in vivo suppressor of colon tumorigenesis.
Topics: Animals; Azoxymethane; Carcinogens; Colon; Colonic Neoplasms; Cyclin D1; Humans; Hydroxyprostaglandin Dehydrogenases; Ki-67 Antigen; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Prostaglandins G | 2006 |
Chemoprevention of colon carcinogenesis by polyethylene glycol: suppression of epithelial proliferation via modulation of SNAIL/beta-catenin signaling.
Topics: Animals; Anticarcinogenic Agents; Azoxymethane; beta Catenin; Cadherins; Cell Proliferation; Colon; Colonic Neoplasms; Cyclin D1; Epithelial Cells; Humans; Male; Polyethylene Glycols; Rats; Rats, Inbred F344; Signal Transduction; Snail Family Transcription Factors; Transcription Factors; Tumor Cells, Cultured | 2006 |
Epidermal growth factor receptor signaling is required for microadenoma formation in the mouse azoxymethane model of colonic carcinogenesis.
Topics: Adenoma; Animals; Azoxymethane; beta Catenin; Carcinogens; Cell Transformation, Neoplastic; Colonic Neoplasms; Cyclin D1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; ErbB Receptors; Gefitinib; Genes, ras; Male; Mice; Mice, Inbred A; Mutation; Quinazolines; Signal Transduction; Up-Regulation | 2007 |
9trans,11trans conjugated linoleic acid inhibits the development of azoxymethane-induced colonic aberrant crypt foci in rats.
Topics: Animals; Apoptosis; Azoxymethane; Biomarkers, Tumor; Cell Division; Colon; Colonic Neoplasms; Cyclin D1; Cyclooxygenase 2; Disease Models, Animal; Dose-Response Relationship, Drug; Immunohistochemistry; Intestinal Mucosa; Linoleic Acids, Conjugated; Lipids; Male; PPAR gamma; Precancerous Conditions; Random Allocation; Rats; Rats, Inbred F344 | 2007 |
Inhibition of azoxymethane-induced colonic aberrant crypt foci formation by silibinin in male Fisher 344 rats.
Topics: Animals; Antineoplastic Agents; Azoxymethane; Carcinogens; Carcinoma; Colonic Neoplasms; Cyclin D1; Cyclooxygenase 2; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Intestinal Mucosa; Male; Nitric Oxide Synthase Type II; Precancerous Conditions; Proliferating Cell Nuclear Antigen; Rats; Rats, Inbred F344; Silybin; Silymarin | 2008 |
Epigenetic modulation of the retinoid X receptor alpha by green tea in the azoxymethane-Apc Min/+ mouse model of intestinal cancer.
Topics: Adenoma; Animals; Azoxymethane; beta Catenin; Camellia sinensis; Carcinogens; Cyclin D1; Disease Models, Animal; DNA Methylation; Down-Regulation; Epigenesis, Genetic; Female; Genes, APC; Immunoenzyme Techniques; Intestinal Neoplasms; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Promoter Regions, Genetic; Retinoid X Receptor alpha; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tea | 2009 |
Inhibition of colon carcinogenesis by 2-methoxy-5-amino-N-hydroxybenzamide, a novel derivative of mesalamine.
Topics: Aminosalicylic Acids; Animals; Anticarcinogenic Agents; Azoxymethane; Benzamides; Carcinogens; Cell Death; Cell Division; Colitis; Colonic Neoplasms; Cyclin D1; Dextran Sulfate; eIF-2 Kinase; Endoplasmic Reticulum; Flow Cytometry; G1 Phase; Gene Silencing; HCT116 Cells; Humans; Mesalamine; Mice; Resting Phase, Cell Cycle; Xenograft Model Antitumor Assays | 2010 |
Luteolin inhibits cell proliferation during Azoxymethane-induced experimental colon carcinogenesis via Wnt/ β-catenin pathway.
Topics: Animals; Azoxymethane; beta Catenin; Blotting, Western; Cell Proliferation; Colonic Neoplasms; Cyclin D1; Drug Screening Assays, Antitumor; Fluorescent Antibody Technique; Gene Expression Regulation, Neoplastic; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Luteolin; Male; Mice; Polyamines; Proliferating Cell Nuclear Antigen; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Silver Staining; Wnt Proteins | 2011 |
Dietary intake of pterostilbene, a constituent of blueberries, inhibits the beta-catenin/p65 downstream signaling pathway and colon carcinogenesis in rats.
Topics: Animals; Azoxymethane; beta Catenin; Colonic Neoplasms; Cyclin D1; Cyclooxygenase 2; Cytokines; HT29 Cells; Humans; Male; Nitric Oxide Synthase Type II; Phosphorylation; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins c-myc; Rats; Rats, Inbred F344; Signal Transduction; Stilbenes; Transcription Factor RelA | 2010 |
Dietary-feeding of grape seed extract prevents azoxymethane-induced colonic aberrant crypt foci formation in fischer 344 rats.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Azoxymethane; beta Catenin; Cell Proliferation; Colon; Colorectal Neoplasms; Cyclin D1; Cyclooxygenase 2; Gene Expression Regulation, Neoplastic; Grape Seed Extract; Microtubule-Associated Proteins; NF-kappa B; Nitric Oxide Synthase Type II; Rats; Rats, Inbred F344; Survivin | 2010 |
Combination of atorvastatin with sulindac or naproxen profoundly inhibits colonic adenocarcinomas by suppressing the p65/β-catenin/cyclin D1 signaling pathway in rats.
Topics: Adenocarcinoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticholesteremic Agents; Antineoplastic Combined Chemotherapy Protocols; Atorvastatin; Azoxymethane; beta Catenin; Carcinogens; Colonic Neoplasms; Cyclin D1; eIF-2 Kinase; Enzyme-Linked Immunosorbent Assay; Heptanoic Acids; Immunoenzyme Techniques; Interleukin-4; Male; Naproxen; Nitric Oxide Synthase Type II; Pyrroles; Rats; Rats, Inbred F344; Signal Transduction; Sulindac; Tumor Necrosis Factor-alpha | 2011 |
Cocoa-rich diet prevents azoxymethane-induced colonic preneoplastic lesions in rats by restraining oxidative stress and cell proliferation and inducing apoptosis.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Azoxymethane; bcl-2-Associated X Protein; Cacao; Caspase 3; Cell Proliferation; Colon; Colonic Neoplasms; Cyclin D1; Diet; Gene Expression Regulation; Oxidative Stress; Precancerous Conditions; Rats | 2011 |
δ- and γ-tocopherols, but not α-tocopherol, inhibit colon carcinogenesis in azoxymethane-treated F344 rats.
Topics: Aldehydes; alpha-Tocopherol; Animals; Anticarcinogenic Agents; Azoxymethane; Colonic Neoplasms; Cyclin D1; Dinoprost; Dinoprostone; gamma-Tocopherol; Immunohistochemistry; Male; Models, Chemical; Rats; Rats, Inbred F344; Tocopherols; Tyrosine | 2012 |
Genistein, a soya isoflavone, prevents azoxymethane-induced up-regulation of WNT/β-catenin signalling and reduces colon pre-neoplasia in rats.
Topics: Aberrant Crypt Foci; Animals; Azoxymethane; Biomarkers; Carcinogens; Colon, Descending; Colonic Neoplasms; Cyclin D1; Disease Models, Animal; Down-Regulation; Female; Genistein; Lactation; Male; Maternal Nutritional Physiological Phenomena; Precancerous Conditions; Pregnancy; Proto-Oncogene Proteins c-myc; Rats; Rats, Sprague-Dawley; Soybean Proteins; Wnt Signaling Pathway | 2013 |
Extracellular calcium-sensing receptor/PTH knockout mice colons have increased Wnt/β-catenin signaling, reduced non-canonical Wnt signaling, and increased susceptibility to azoxymethane-induced aberrant crypt foci.
Topics: Aberrant Crypt Foci; Animals; Azoxymethane; beta Catenin; Blotting, Western; Colon; Cyclin D1; Genetic Predisposition to Disease; Intestine, Small; Matrix Metalloproteinase 7; Mice; Mice, Knockout; Parathyroid Hormone; Peroxidase; Receptor Tyrosine Kinase-like Orphan Receptors; Receptors, Calcium-Sensing; Receptors, Tumor Necrosis Factor, Type I; Signal Transduction; Wnt Proteins; Wnt-5a Protein; Wnt3A Protein | 2013 |
Cholinergic muscarinic receptor activation augments murine intestinal epithelial cell proliferation and tumorigenesis.
Topics: Adenocarcinoma; Animals; Azoxymethane; Bethanechol; Cell Proliferation; Cell Transformation, Neoplastic; Colonic Neoplasms; Cyclin D1; Cyclooxygenase 2; ErbB Receptors; Gene Expression; Hypoxia-Inducible Factor 1, alpha Subunit; Intestinal Mucosa; Male; Matrix Metalloproteinase 10; Matrix Metalloproteinase 13; Matrix Metalloproteinase 7; Mice; Muscarinic Agonists; Proto-Oncogene Proteins c-myc; Receptor, Muscarinic M3; RNA, Messenger; Signal Transduction; Tumor Burden | 2013 |
Chemopreventive effects of PBI-Se, a selenium-containing analog of PBIT, on AOM-induced aberrant crypt foci in F344 rats.
Topics: Aberrant Crypt Foci; Animals; Apoptosis; Azoxymethane; Caco-2 Cells; Cell Line, Tumor; Cell Proliferation; Chemoprevention; Colonic Neoplasms; Cyclin D1; Humans; Interleukin-6; Interleukin-8; Male; Nitric Oxide Synthase Type II; Rats; Rats, Inbred F344; Selenium Compounds; Thiourea | 2013 |
Berberine regulates AMP-activated protein kinase signaling pathways and inhibits colon tumorigenesis in mice.
Topics: AMP-Activated Protein Kinases; Animals; Apoptosis; Azoxymethane; Berberine; Carcinogenesis; Caspase 3; Cell Line, Tumor; Colon; Colorectal Neoplasms; Cyclin D1; Cyclooxygenase 2; eIF-2 Kinase; Female; HCT116 Cells; Humans; Mice; NF-kappa B; Phosphorylation; Protein Serine-Threonine Kinases; Signal Transduction; TOR Serine-Threonine Kinases; Tumor Suppressor Protein p53 | 2015 |
Carnosic acid suppresses colon tumor formation in association with antiadipogenic activity.
Topics: 3T3-L1 Cells; Abietanes; Adipocytes; Adipogenesis; Adiponectin; Adiposity; Animals; Apoptosis; Azoxymethane; bcl-X Protein; Cell Proliferation; Colon; Colonic Neoplasms; Cyclin D1; Dextran Sulfate; Extracellular Signal-Regulated MAP Kinases; HT29 Cells; Humans; Insulin; Insulin-Like Growth Factor I; Interleukin-6; Leptin; Male; Mice; Plant Extracts; Proto-Oncogene Proteins c-akt; Receptor, Insulin; Receptors, Leptin; STAT3 Transcription Factor | 2014 |
Smad2/3 linker phosphorylation is a possible marker of cancer stem cells and correlates with carcinogenesis in a mouse model of colitis-associated colorectal cancer.
Topics: Animals; Azoxymethane; beta Catenin; Biomarkers, Tumor; Carcinogenesis; Colitis; Colorectal Neoplasms; Cyclin D1; Dextran Sulfate; Disease Models, Animal; Ki-67 Antigen; Male; Mice; Neoplastic Stem Cells; Phosphorylation; Proto-Oncogene Proteins c-myc; Serine; Signal Transduction; Smad2 Protein; Smad3 Protein; SOX9 Transcription Factor | 2015 |
Nexrutine inhibits azoxymethane-induced colonic aberrant crypt formation in rat colon and induced apoptotic cell death in colon adenocarcinoma cells.
Topics: Aberrant Crypt Foci; Animals; Apoptosis; Azoxymethane; Biomarkers, Tumor; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colonic Neoplasms; Cyclin D1; Cyclooxygenase 2; Gene Expression Regulation, Neoplastic; Humans; Male; Nitric Oxide Synthase Type II; Plant Extracts; Rats; Xenograft Model Antitumor Assays | 2016 |
Boswellia serrata resin extract alleviates azoxymethane (AOM)/dextran sodium sulfate (DSS)-induced colon tumorigenesis.
Topics: Animals; Azoxymethane; Boswellia; Cell Proliferation; Colonic Neoplasms; Cyclin D1; Dextran Sulfate; Glycogen Synthase Kinase 3 beta; Male; MAP Kinase Signaling System; Mice; Mice, Inbred ICR; Plant Extracts; Proto-Oncogene Proteins c-akt; Resins, Plant | 2017 |
Tumor Necrosis Factor Ligand-Related Molecule 1A Regulates the Occurrence of Colitis-Associated Colorectal Cancer.
Topics: Animals; Azoxymethane; beta Catenin; Cell Movement; Cell Proliferation; Colitis; Colorectal Neoplasms; Cyclin D1; Dextran Sulfate; Disease Models, Animal; Gene Expression Regulation, Neoplastic; HCT116 Cells; HT29 Cells; Humans; Mice, Inbred C57BL; Mice, Transgenic; Neoplasm Invasiveness; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins c-myc; Time Factors; Tumor Necrosis Factor Ligand Superfamily Member 15; Wnt Signaling Pathway | 2018 |
Dietary Mixed Cereal Grains Ameliorate the Azoxymethane and Dextran Sodium Sulfate-Induced Colonic Carcinogenesis in C57BL/6J Mice.
Topics: Animals; Azoxymethane; Carcinogenesis; Caspase 3; Colon; Colonic Neoplasms; Colorectal Neoplasms; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p21; Cyclooxygenase 2; Cytokines; Dextran Sulfate; Dietary Carbohydrates; Disease Models, Animal; Edible Grain; Interleukin-1beta; Interleukin-6; Male; Mice; Mice, Inbred C57BL; Nitric Oxide Synthase Type II; RNA, Messenger; Tumor Necrosis Factors; Tumor Suppressor Protein p53 | 2020 |
Suppression of C-C chemokine receptor 1 is a key regulation for colon cancer chemoprevention in AOM/DSS mice by fucoxanthin.
Topics: Animals; Azoxymethane; Chemokines, CC; Colonic Neoplasms; Cyclin D1; Dextran Sulfate; Disease Models, Animal; Humans; Male; Mice; Mice, Inbred ICR; Proto-Oncogene Proteins c-akt; Receptors, CCR1; Smad2 Protein; Xanthophylls | 2022 |
Aspirin Inhibits Carcinogenesis of Intestinal Mucosal Cells in UC Mice Through Inhibiting IL-6/JAK/STAT3 Signaling Pathway and Modulating Apoptosis and Proliferation.
Topics: Animals; Apoptosis; Aspirin; Azoxymethane; Carcinogenesis; Cell Proliferation; Colitis, Ulcerative; Colorectal Neoplasms; Cyclin D1; Dextran Sulfate; Hyperplasia; Inflammation; Interleukin-10; Interleukin-6; Janus Kinases; Mice; Proliferating Cell Nuclear Antigen; Signal Transduction; STAT3 Transcription Factor | 2022 |
Portulaca oleracea extract reduces gut microbiota imbalance and inhibits colorectal cancer progression via inactivation of the Wnt/β-catenin signaling pathway.
Topics: Animals; Azoxymethane; beta Catenin; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Cyclin D1; Gastrointestinal Microbiome; Gene Expression Regulation, Neoplastic; Mice; Portulaca; Wnt Signaling Pathway | 2022 |
Zearalenone attenuates colitis associated colorectal tumorigenesis through Ras/Raf/ERK pathway suppression and SCFA-producing bacteria promotion.
Topics: Animals; Azoxymethane; Bacteria; Carcinogenesis; Cell Transformation, Neoplastic; Colitis; Colorectal Neoplasms; Cyclin D1; Dextran Sulfate; Disease Models, Animal; Humans; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Zearalenone | 2023 |
A Short-Term Model of Colitis-Associated Colorectal Cancer That Suggests Initial Tumor Development and the Characteristics of Cancer Stem Cells.
Topics: Animals; Azoxymethane; beta Catenin; Colitis; Colitis-Associated Neoplasms; Colorectal Neoplasms; Cyclin D1; Dextran Sulfate; Disease Models, Animal; Humans; Ki-67 Antigen; Mice; Mice, Inbred C57BL; Neoplastic Stem Cells | 2023 |