Compounds > azoxymethane
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azoxymethane and big gastrin

azoxymethane has been researched along with big gastrin in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (83.33)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Given, R; Singh, P; Varro, A; Velasco, M; Wang, TC; Wargovich, M1
Given, R; Singh, P; Varro, A; Velasco, M; Wang, TC1
Ceci, J; Cobb, S; Singh, P; Varro, A; Velasco, M; Wood, T1
Dimaline, R; Dockray, GJ; Kirton, CM; Ottewell, PD; Pritchard, DM; Varro, A; Wang, TC; Watson, AJ1
Baik, GH; Gordon, SA; Jin, G; Pritchard, DM; Quante, M; Ramanathan, V; Shulkes, A; Tu, S; Varro, A; Wang, SS; Wang, TC; Yang, X1
Dubeykovskiy, A; Jin, G; Ramanathan, V; Takaishi, S; Wang, TC; Westphalen, CB; Whelan, A1

Other Studies

6 other study(ies) available for azoxymethane and big gastrin

ArticleYear
Mice overexpressing progastrin are predisposed for developing aberrant colonic crypt foci in response to AOM.
    American journal of physiology. Gastrointestinal and liver physiology, 2000, Volume: 278, Issue:3

    Topics: Animals; Azoxymethane; Bromodeoxyuridine; Carcinogens; Colon; Colonic Neoplasms; Disease Susceptibility; Gastrins; Humans; Mice; Mice, Inbred Strains; Mice, Transgenic; Precancerous Conditions; Protein Precursors

2000
Progastrin expression predisposes mice to colon carcinomas and adenomas in response to a chemical carcinogen.
    Gastroenterology, 2000, Volume: 119, Issue:1

    Topics: Adenoma; Amides; Animals; Azoxymethane; Carcinogens; Carcinoma; Colonic Neoplasms; Gastrins; Incidence; Mice; Mice, Transgenic; Neoplasms, Multiple Primary; Protein Precursors; Reference Values; Survival Analysis

2000
Intestinal expression of mutant and wild-type progastrin significantly increases colon carcinogenesis in response to azoxymethane in transgenic mice.
    Cancer, 2004, Mar-15, Volume: 100, Issue:6

    Topics: Animals; Azoxymethane; Carcinogens; Colonic Neoplasms; Female; Gastrins; Humans; Male; Mice; Mice, Transgenic; Polymerase Chain Reaction; Precancerous Conditions; Protein Precursors; Radioimmunoassay

2004
COOH-terminal 26-amino acid residues of progastrin are sufficient for stimulation of mitosis in murine colonic epithelium in vivo.
    American journal of physiology. Gastrointestinal and liver physiology, 2005, Volume: 288, Issue:3

    Topics: Amino Acid Sequence; Animals; Antimetabolites; Apoptosis; Azoxymethane; Bromodeoxyuridine; Carcinogens; Colon; DNA Damage; Epithelial Cells; Gamma Rays; Gastrins; Genotype; Humans; Immunohistochemistry; Mice; Mice, Knockout; Mice, Transgenic; Mitogens; Mitosis; Peptide Fragments; Protein Precursors

2005
Inactivating cholecystokinin-2 receptor inhibits progastrin-dependent colonic crypt fission, proliferation, and colorectal cancer in mice.
    The Journal of clinical investigation, 2009, Volume: 119, Issue:9

    Topics: Animals; Apoptosis; Azoxymethane; Cell Proliferation; Colon; Colorectal Neoplasms; Gastrins; Gene Expression; Humans; Hyaluronan Receptors; Mice; Mice, Knockout; Mice, Transgenic; Protein Precursors; Receptor, Cholecystokinin B; Recombinant Proteins

2009
P53 gene mutation increases progastrin dependent colonic proliferation and colon cancer formation in mice.
    Cancer investigation, 2012, Volume: 30, Issue:4

    Topics: Aberrant Crypt Foci; Animals; Azoxymethane; Carcinogens; Cell Proliferation; Cell Transformation, Neoplastic; Colonic Neoplasms; Disease Models, Animal; Female; Gastrins; Humans; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Protein Precursors; Tumor Suppressor Protein p53

2012