Page last updated: 2024-08-25

azoprocarbazine and procarbazine

azoprocarbazine has been researched along with procarbazine in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19905 (55.56)18.7374
1990's2 (22.22)18.2507
2000's2 (22.22)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Albano, E; Goria-Gatti, L; Iannone, A; Poli, G; Tomasi, A1
Callingham, BA; Holt, A; Sharman, DF1
Cummings, SW; Moloney, SJ; Prough, RA; Wiebkin, P1
Shiba, DA; Weinkam, RJ1
Brown, MI; Dannan, GA; Guengerich, FP; Prough, RA1
Moloney, SJ; Prough, RA1
Prough, RA; Wiebkin, P1
Baumann, F; Matthias, M; Preiss, R; Regenthal, R1
Gasowska-Bajger, B; Wojtasek, H1

Other Studies

9 other study(ies) available for azoprocarbazine and procarbazine

ArticleYear
In vitro and in vivo evidence for the formation of methyl radical from procarbazine: a spin-trapping study.
    Carcinogenesis, 1992, Volume: 13, Issue:5

    Topics: Animals; Electron Spin Resonance Spectroscopy; Free Radicals; Hydrazones; Liver; Male; Microsomes, Liver; Monomethylhydrazine; NADP; Procarbazine; Rats

1992
Effects in-vitro of procarbazine metabolites on some amine oxidase activities in the rat.
    The Journal of pharmacy and pharmacology, 1992, Volume: 44, Issue:6

    Topics: Adipose Tissue, Brown; Amine Oxidase (Copper-Containing); Animals; Benzylamines; Carbon Radioisotopes; In Vitro Techniques; Liver; Monomethylhydrazine; Oxidoreductases Acting on CH-NH Group Donors; Procarbazine; Rats

1992
Metabolic activation of the terminal N-methyl group of N-isopropyl-alpha-(2-methylhydrazino)-p-toluamide hydrochloride (procarbazine).
    Carcinogenesis, 1985, Volume: 6, Issue:3

    Topics: Animals; Biotransformation; Free Radicals; Glutathione; In Vitro Techniques; Methane; Microsomes, Liver; Procarbazine; Protein Binding; Rats; Rats, Inbred Strains

1985
The in vivo cytotoxic activity of procarbazine and procarbazine metabolites against L1210 ascites leukemia cells in CDF1 mice and the effects of pretreatment with procarbazine, phenobarbital, diphenylhydantoin, and methylprednisolone upon in vivo procarba
    Cancer chemotherapy and pharmacology, 1983, Volume: 11, Issue:2

    Topics: Animals; Drug Interactions; Leukemia L1210; Male; Methylprednisolone; Mice; Mice, Inbred Strains; Phenobarbital; Phenytoin; Procarbazine

1983
Major isozymes of rat liver microsomal cytochrome P-450 involved in the N-oxidation of N-isopropyl-alpha-(2-methylazo)-p-toluamide, the azo derivative of procarbazine.
    Cancer research, 1984, Volume: 44, Issue:2

    Topics: Animals; Antibodies; Cytochrome P-450 Enzyme System; Isoenzymes; Male; Microsomes, Liver; Oxidation-Reduction; Procarbazine; Rats; Rats, Inbred Strains

1984
Studies on the pathway of methane formation from procarbazine, a 2-methylbenzylhydrazine derivative, by rat liver microsomes.
    Archives of biochemistry and biophysics, 1983, Volume: 221, Issue:2

    Topics: Animals; In Vitro Techniques; Male; Methane; Microsomes, Liver; Procarbazine; Rats; Rats, Inbred Strains

1983
Oxidative metabolism of N-isopropyl-alpha-(2-methylazo)-p-toluamide (azoprocarbazine) by rodent liver microsomes.
    Cancer research, 1980, Volume: 40, Issue:10

    Topics: Animals; Benzoflavones; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Kinetics; Mass Spectrometry; Microsomes, Liver; Oxidation-Reduction; Phenobarbital; Procarbazine; Protein Binding; Rabbits; Rats

1980
Plasma kinetics of procarbazine and azo-procarbazine in humans.
    Anti-cancer drugs, 2006, Volume: 17, Issue:1

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents; Area Under Curve; Female; Half-Life; Humans; Male; Metabolic Clearance Rate; Middle Aged; Neoplasms; Procarbazine

2006
Indirect oxidation of the antitumor agent procarbazine by tyrosinase--possible application in designing anti-melanoma prodrugs.
    Bioorganic & medicinal chemistry letters, 2008, Jun-01, Volume: 18, Issue:11

    Topics: Agaricales; Antineoplastic Agents; Hydrazines; Melanoma; Molecular Structure; Monophenol Monooxygenase; Oxidation-Reduction; Oxygen Consumption; Procarbazine; Prodrugs; Structure-Activity Relationship

2008