azomycin has been researched along with tirapazamine in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.76) | 18.7374 |
| 1990's | 8 (38.10) | 18.2507 |
| 2000's | 7 (33.33) | 29.6817 |
| 2010's | 5 (23.81) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Stratford, IJ | 1 |
| Chaplin, DJ | 1 |
| Adams, GE; Bremner, JC; Cole, S; Edwards, HS; Stratford, IJ | 1 |
| Walton, MI; Wolf, CR; Workman, P | 1 |
| Adams, GE; Stratford, IJ | 1 |
| Abe, M; Hiraoka, M; Murata, R; Oya, N; Sasai, K; Shibamoto, Y; Shibata, T; Takagi, T | 1 |
| Abe, M; Hiraoka, M; Murata, R; Oya, N; Sasai, K; Shibamoto, Y; Shibata, T; Takagi, T; Takahashi, M | 1 |
| Baguley, BC; Lash, CJ; Li, AE; Rutland, M; Wilson, WR; Zwi, LJ | 1 |
| Melo, T; Misra, V; Rauth, AM | 1 |
| Lee, AE; Wilson, WR | 1 |
| Ito, M; Ogino, H; Shibamoto, Y; Sugie, C | 1 |
| Fitzmaurice, RJ; Lunt, SJ; Stratford, IJ; Telfer, BA; Williams, KJ | 1 |
| Down, JD; Mauch, P; Parmar, K; Sackstein, R; Vergilio, JA | 1 |
| Mankoff, DA; Rajendran, JG | 1 |
| Andratschke, N; Beck, R; Carlsen, JM; Huisman, MC; Lebschi, JA; Machulla, HJ; Picchio, M; Piert, M; Röper, B; Souvatzoglou, M | 1 |
| Le, QT | 1 |
| Ali, M; Babur, M; Bloomer, WD; Cawthorne, C; Julyan, PJ; Lunt, SJ; Papadopoulou, MV; Price, PM; Smigova, A; Stratford, IJ; Telfer, BA; Williams, KJ | 1 |
| Chopra, S; Doppalapudi, RS; Franzblau, SG; Green, CE; Iyer, LV; Koolpe, GA; Madrid, PB; Matsuyama, KN; Riccio, ES; Ryan, KJ; Tambo-Ong, AA; Tran, TB; Wan, B | 1 |
| Ashoorzadeh, A; Ding, K; Guise, CP; Lin, WH; Mowday, AM; Patterson, AV; Smaill, JB; Wu, DH; Yuan, R | 1 |
| Brown, KR; Goldstein, DP; Gu, Y; Hunter, FW; Joshi, N; Ketela, T; Koritzinsky, M; Moffat, J; Rischin, D; Shalev, Z; Solomon, B; Sreebhavan, S; Vellanki, RN; Wang, J; Weinreb, I; Wilson, WR; Wouters, BG; Young, RJ | 1 |
| Chang, H; Dong, H; Lu, H; Meng, X; Zhang, K; Zhang, X; Zhang, Y | 1 |
3 review(s) available for azomycin and tirapazamine
| Article | Year |
|---|---|
Bioreductive drugs in cancer therapy.
Topics: Animals; Antineoplastic Agents; Antioxidants; Cell Hypoxia; Humans; Misonidazole; Neoplasms; Nitroimidazoles; Prodrugs; Radiation-Sensitizing Agents; Tirapazamine; Triazines | 1992 |
The Japanese experiences with hypoxia-targeting pharmacoradiotherapy: from hypoxic cell sensitisers to radiation-activated prodrugs.
Topics: Asian People; Cell Hypoxia; Clinical Trials as Topic; Humans; Imidazoles; Neoplasms; Nitroimidazoles; Prodrugs; Radiation; Radiation-Sensitizing Agents; Tirapazamine; Triazines | 2004 |
Bioreductive prodrugs as cancer therapeutics: targeting tumor hypoxia.
Topics: Anthraquinones; Antineoplastic Agents; Aziridines; Cell Hypoxia; Humans; Indolequinones; Molecular Structure; NAD(P)H Dehydrogenase (Quinone); Neoplasms; Nitrogen Mustard Compounds; Nitroimidazoles; Phosphoramide Mustards; Prodrugs; Tirapazamine; Triazines | 2014 |
18 other study(ies) available for azomycin and tirapazamine
| Article | Year |
|---|---|
Bioreductive therapy.
Topics: Antineoplastic Agents; Cell Hypoxia; Humans; Misonidazole; Nitroimidazoles; Oxidation-Reduction; Prodrugs; Radiation-Sensitizing Agents; Tirapazamine; Triazines | 1992 |
Bioreductive drugs as post-irradiation sensitizers: comparison of dual function agents with SR 4233 and the mitomycin C analogue EO9.
Topics: Animals; Antineoplastic Agents; Aziridines; Cell Hypoxia; Cell Survival; Combined Modality Therapy; Dose-Response Relationship, Drug; Indolequinones; Indoles; Mice; Mice, Inbred C3H; Misonidazole; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Prodrugs; Tirapazamine; Triazines | 1992 |
Molecular enzymology of the reductive bioactivation of hypoxic cell cytotoxins.
Topics: Animals; Antineoplastic Agents; Aziridines; Azirines; Biotransformation; Carbon Monoxide; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Cytosol; Male; Mice; Mice, Inbred C3H; Microsomes, Liver; Nitroimidazoles; Oxidation-Reduction; Radiation-Sensitizing Agents; Tirapazamine; Triazines | 1989 |
Bioreductive drugs for cancer therapy: the search for tumor specificity.
Topics: Animals; Antineoplastic Agents; Humans; Neoplasms; Nitric Oxide; Nitroimidazoles; Oxidation-Reduction; Photochemotherapy; Porfiromycin; Prodrugs; Tirapazamine; Triazines | 1994 |
Comparison of in vivo efficacy of hypoxic cytotoxin tirapazamine and hypoxic cell radiosensitizer KU-2285 in combination with single and fractionated irradiation.
Topics: Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Combined Modality Therapy; Female; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Neoplasms, Experimental; Nitroimidazoles; Radiotherapy Dosage; Tirapazamine; Triazines | 1996 |
Tirapazamine: hypoxic cytotoxicity and interaction with radiation as assessed by the micronucleus assay.
Topics: Animals; Antineoplastic Agents; Cell Hypoxia; Dose-Response Relationship, Radiation; Humans; Mice; Micronuclei, Chromosome-Defective; Micronucleus Tests; Nitroimidazoles; Radiation-Sensitizing Agents; Tirapazamine; Triazines; Tumor Cells, Cultured | 1996 |
Enhancement of the anti-tumour effects of the antivascular agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA) by combination with 5-hydroxytryptamine and bioreductive drugs.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Drug Synergism; Female; Mice; Mice, Inbred C3H; Nitrogen Mustard Compounds; Nitroimidazoles; Prodrugs; Regional Blood Flow; Serotonin; Tirapazamine; Triazines; Xanthenes; Xanthones | 1998 |
Bioreductive therapies: an overview of drugs and their mechanisms of action.
Topics: Animals; Antineoplastic Agents; Aziridines; Cell Hypoxia; DNA, Neoplasm; Forecasting; Humans; Indolequinones; Indoles; Misonidazole; Mitomycin; Nitrofurans; Nitroimidazoles; Oxidation-Reduction; Prodrugs; Radiation-Sensitizing Agents; Tirapazamine; Triazines | 1998 |
Hypoxia-dependent retinal toxicity of bioreductive anticancer prodrugs in mice.
Topics: Animals; Antineoplastic Agents; Dose-Response Relationship, Drug; Female; Hypoxia; Light; Mice; Mice, Inbred C57BL; Nitroimidazoles; Oxidation-Reduction; Prodrugs; Radiation-Sensitizing Agents; Retina; Tirapazamine; Triazines | 2000 |
Tirapazamine administered as a neoadjuvant to radiotherapy reduces metastatic dissemination.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Combined Modality Therapy; Female; Hypoxia; Mice; Mice, Inbred C3H; Neoadjuvant Therapy; Neoplasm Metastasis; Neoplasm Transplantation; Neovascularization, Pathologic; Nitroimidazoles; Radiation-Sensitizing Agents; Sarcoma, Experimental; Tirapazamine; Treatment Outcome; Triazines | 2005 |
Distribution of hematopoietic stem cells in the bone marrow according to regional hypoxia.
Topics: Animals; Benzimidazoles; Bone Marrow Cells; Cell Differentiation; Hematopoietic Stem Cells; Hematopoietic System; Hypoxia; Mice; Mice, Inbred C57BL; Nitroimidazoles; Oxygen; Perfusion; Stem Cells; Tirapazamine; Triazines | 2007 |
Beyond detection: novel applications for PET imaging to guide cancer therapy.
Topics: Animals; Antineoplastic Agents; Cell Hypoxia; Fluorine Radioisotopes; Head and Neck Neoplasms; Humans; Mammary Neoplasms, Experimental; Nitroimidazoles; Positron-Emission Tomography; Radiation-Sensitizing Agents; Tirapazamine; Triazines | 2007 |
Pretreatment 18F-FAZA PET predicts success of hypoxia-directed radiochemotherapy using tirapazamine.
Topics: Animals; Antineoplastic Agents; Cell Hypoxia; Cell Line, Tumor; Combined Modality Therapy; Female; Fluorine Radioisotopes; Mammary Neoplasms, Experimental; Mice; Mice, Nude; Neoplasm Transplantation; Nitroimidazoles; Positron-Emission Tomography; Radiation-Sensitizing Agents; Radiopharmaceuticals; Tirapazamine; Transplantation, Heterologous; Triazines; Whole Body Imaging | 2007 |
Identifying and targeting hypoxia in head and neck cancer: a brief overview of current approaches.
Topics: Antigens, Neoplasm; Biomarkers; Carbonic Anhydrase IX; Carbonic Anhydrases; Carcinoma, Squamous Cell; Cell Hypoxia; Electrodes; Etanidazole; Head and Neck Neoplasms; Humans; Hydrocarbons, Fluorinated; Intracellular Signaling Peptides and Proteins; Mitochondrial Proteins; Neoplasm Proteins; Nitroimidazoles; Osteopontin; Oxygen; Partial Pressure; Radiation-Sensitizing Agents; Tirapazamine; Triazines | 2007 |
The hypoxia-selective cytotoxin NLCQ-1 (NSC 709257) controls metastatic disease when used as an adjuvant to radiotherapy.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Hypoxia; Cell Line, Tumor; Chemotherapy, Adjuvant; Combined Modality Therapy; Drug Administration Schedule; Drug Evaluation, Preclinical; Imidazoles; Lung Neoplasms; Mice; Mice, Inbred C3H; Neoplasm Metastasis; Nitroimidazoles; Quinolines; Sarcoma; Tirapazamine; Triazines | 2010 |
Discovery and optimization of benzotriazine di-N-oxides targeting replicating and nonreplicating Mycobacterium tuberculosis.
Topics: Animals; Antitubercular Agents; Chlorocebus aethiops; Drug Discovery; Female; Isomerism; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Nitrofurans; Nitroimidazoles; Oxides; Quinoxalines; Rats; Tirapazamine; Triazines; Tuberculosis; Vero Cells | 2012 |
Identification of P450 Oxidoreductase as a Major Determinant of Sensitivity to Hypoxia-Activated Prodrugs.
Topics: Activation, Metabolic; Antineoplastic Agents; Biomarkers; Carcinoma, Squamous Cell; Cell Hypoxia; Cell Line, Tumor; Chemoradiotherapy; Cyclic N-Oxides; Cytochrome P-450 Enzyme System; Head and Neck Neoplasms; High-Throughput Screening Assays; Humans; Neoplasm Proteins; Nitroimidazoles; Papillomaviridae; Papillomavirus Infections; Phosphoramide Mustards; Prodrugs; Retrospective Studies; RNA Interference; RNA, Messenger; RNA, Small Interfering; Tirapazamine; Triazines; Tumor Microenvironment; Tumor Stem Cell Assay | 2015 |
Light-triggered theranostic liposomes for tumor diagnosis and combined photodynamic and hypoxia-activated prodrug therapy.
Topics: Animals; Antineoplastic Agents; Chlorophyllides; Delayed-Action Preparations; Humans; Light; Liposomes; MCF-7 Cells; Mice; Neoplasms; Nitroimidazoles; Optical Imaging; Photosensitizing Agents; Polyethylene Glycols; Porphyrins; Theranostic Nanomedicine; Tirapazamine; Tumor Hypoxia | 2018 |