Page last updated: 2024-08-21

azomycin and iodoazomycin arabinoside

azomycin has been researched along with iodoazomycin arabinoside in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's16 (64.00)18.2507
2000's5 (20.00)29.6817
2010's4 (16.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chapman, JD; Golberg, L; Mannan, RH; McEwan, AJ; Mercer, JR; Parliament, MB; Urtasun, RC; Wiebe, LI1
Chapman, JD; Roa, WH1
Chapman, JD; Lee, J; Mannan, RH; Mercer, JR; Somayaji, VV; Wiebe, LI1
al-Arafaj, A; Hutchison, K; Mannan, RH; McEwan, AJ; Mercer, J; Ryan, EA; Wiebe, LI1
Chapman, JD; Golberg, LE; Groshar, D; Hoskinson, M; Mannan, RH; McEwan, AJ; Mercer, JR; Parliament, MB; Urtasun, RC; Wiebe, LI1
Chapman, JD; Mannan, RH; McEwan, AJ; McPhee, MS; Mercer, JR; Moore, RB; Wiebe, LI1
Biskupiak, JE; Krohn, KA1
Chapman, JD; Coia, LR; Engelhardt, EL; Fenning, MC; Schneider, RF; Stobbe, CC1
Chapman, JD; Mannan, RH; McEwan, AJ; Mercer, JR; Morin, C; Parliament, MB; Urtasun, RC; Wiebe, LI1
Stypinski, D; Wiebe, LI1
Gordon, I; Lythgoe, MF; McEwan, AJ; Wiebe, LI; Williams, SR1
Mercer, JR; Stypinski, D; Wiebe, LI1
Busza, AL; Gadian, DG; Gordon, I; Lythgoe, MF; McEwan, AJ; Wiebe, L; Williams, SR1
McEwan, AJ; Mercer, JR; Schmidt, RP; Stypinski, D; Tam, YK; Wiebe, LI1
Critchley, M; Maltby, P; McEwan, AJ; O'Driscoll, K; Vinjamuri, S; Wiebe, LI1
McEwan, AJ; Mercer, JR; Stypinski, D; Tam, YK; Wiebe, LI1
Kumar, P; Lee, HC; McEwan, AJ; Mercer, JR; Wiebe, LI1
McEwan, AJ; McQuarrie, SA; Mercer, JR; Stypinski, D; Tam, YK; Wiebe, LI1
Beiki, D; Kumar, P; Ohkura, K; Seki, K; Wiebe, LI1
Kumar, P; McEwan, AJ; Naimi, E; Wiebe, LI1
Kumar, P; McEwan, AJ; McQuarrie, SA; Wiebe, LI; Zhou, A1
Cheeseman, C; Khlebnikov, V; Kumar, P; Liang, H; Shustov, G; Wiebe, LI; Yang, XH; Zheng, W1
McEwan, AJ; Mercer, JR; Wiebe, LI1
Kumar, P; Narain, R; Quan, S; Wang, Y; Zhou, A1
Cook, GJ; Fong, KW; Goh, V; Tan, T; Wee, J; Yip, C1

Reviews

2 review(s) available for azomycin and iodoazomycin arabinoside

ArticleYear
Pharmacokinetics of SPECT radiopharmaceuticals for imaging hypoxic tissues.
    The quarterly journal of nuclear medicine : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), 1996, Volume: 40, Issue:3

    Topics: Animals; Cell Hypoxia; Humans; Iodine Radioisotopes; Misonidazole; Nitroimidazoles; Radiation-Sensitizing Agents; Radiopharmaceuticals; Technetium; Tomography, Emission-Computed, Single-Photon

1996
Clinical significance of hypoxia in nasopharyngeal carcinoma with a focus on existing and novel hypoxia molecular imaging.
    Chinese clinical oncology, 2016, Volume: 5, Issue:2

    Topics: Biomarkers, Tumor; Carcinoma; Cell Hypoxia; Coordination Complexes; Humans; Magnetic Resonance Imaging; Molecular Imaging; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Nitroimidazoles; Organometallic Compounds; Oxygen; Positron-Emission Tomography; Prognosis; Thiosemicarbazones; Tomography, Emission-Computed, Single-Photon

2016

Trials

1 trial(s) available for azomycin and iodoazomycin arabinoside

ArticleYear
A rapid and simple assay to determine the blood and urine concentrations of 1-(5-[123/125I]iodo-5-deoxyarabinofuranosyl)-2-nitroimidazole, a hypoxic cell marker.
    Journal of pharmaceutical and biomedical analysis, 1998, Volume: 16, Issue:6

    Topics: Biomarkers; Calibration; Cell Hypoxia; Chromatography, High Pressure Liquid; Humans; Indicators and Reagents; Iodine Radioisotopes; Nitroimidazoles; Reference Standards; Spectrophotometry, Ultraviolet

1998

Other Studies

22 other study(ies) available for azomycin and iodoazomycin arabinoside

ArticleYear
Non-invasive assessment of human tumour hypoxia with 123I-iodoazomycin arabinoside: preliminary report of a clinical study.
    British journal of cancer, 1992, Volume: 65, Issue:1

    Topics: Adult; Aged; Carcinoma, Small Cell; Female; Half-Life; Humans; Hypoxia; Iodine Radioisotopes; Lung Neoplasms; Male; Middle Aged; Neoplasms; Nitroimidazoles; Tomography, Emission-Computed

1992
Killing of EMT-6 cells by decays from isotopes incorporated on sensitizer adducts.
    Radiation research, 1992, Volume: 132, Issue:2

    Topics: Animals; Cell Death; Cell Hypoxia; Cell Survival; Cobalt Radioisotopes; Gamma Rays; Iodine Radioisotopes; Kinetics; Mice; Misonidazole; Nitroimidazoles; Radiation-Sensitizing Agents; Time Factors; Tritium; Tumor Cells, Cultured

1992
Radioiodinated 1-(5-iodo-5-deoxy-beta-D-arabinofuranosyl)-2-nitroimidazole (iodoazomycin arabinoside: IAZA): a novel marker of tissue hypoxia.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1991, Volume: 32, Issue:9

    Topics: Animals; Cell Hypoxia; Iodine Radioisotopes; Male; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Neoplasms, Experimental; Nitroimidazoles; Tissue Distribution

1991
An evaluation of iodine-123 iodoazomycinarabinoside as a marker of localized tissue hypoxia in patients with diabetes mellitus.
    European journal of nuclear medicine, 1994, Volume: 21, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Blood Gas Monitoring, Transcutaneous; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Foot; Female; Humans; Iodine Radioisotopes; Male; Middle Aged; Nitroimidazoles; Peripheral Vascular Diseases; Radionuclide Imaging

1994
Imaging tumor hypoxia and tumor perfusion.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1993, Volume: 34, Issue:6

    Topics: Brain Neoplasms; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cell Hypoxia; Female; Glioblastoma; Head and Neck Neoplasms; Humans; Iodine Radioisotopes; Lung Neoplasms; Male; Nitroimidazoles; Organotechnetium Compounds; Oximes; Sarcoma; Soft Tissue Neoplasms; Technetium Tc 99m Exametazime; Tomography, Emission-Computed, Single-Photon

1993
Measurement of PDT-induced hypoxia in Dunning prostate tumors by iodine-123-iodoazomycin arabinoside.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1993, Volume: 34, Issue:3

    Topics: Animals; Brain; Cell Hypoxia; Iodine Radioisotopes; Magnetic Resonance Spectroscopy; Male; Neoplasm Transplantation; Nitroimidazoles; Oxygen; Photochemotherapy; Prostatic Neoplasms; Radionuclide Imaging; Rats; Tumor Cells, Cultured

1993
Second generation hypoxia imaging agents.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1993, Volume: 34, Issue:3

    Topics: Animals; Cell Hypoxia; Iodine Radioisotopes; Male; Nitroimidazoles; Oxygen; Photochemotherapy; Prostatic Neoplasms; Radionuclide Imaging; Rats

1993
Prediction of tumour hypoxia and radioresistance with nuclear medicine markers.
    The British journal of cancer. Supplement, 1996, Volume: 27

    Topics: Animals; Cell Hypoxia; Mice; Mice, SCID; Neoplasms, Experimental; Nitroimidazoles; Radiation Tolerance; Rats; Tomography, Emission-Computed, Single-Photon

1996
Measurement of hypoxia in human tumours by non-invasive spect imaging of iodoazomycin arabinoside.
    The British journal of cancer. Supplement, 1996, Volume: 27

    Topics: Cell Hypoxia; Humans; Neoplasms; Nitroimidazoles; Tomography, Emission-Computed, Single-Photon

1996
Autoradiographic imaging of cerebral ischaemia using a combination of blood flow and hypoxic markers in an animal model.
    European journal of nuclear medicine, 1997, Volume: 24, Issue:1

    Topics: Animals; Brain; Brain Ischemia; Cell Hypoxia; Cerebrovascular Circulation; Iodine Radioisotopes; Male; Nitroimidazoles; Organotechnetium Compounds; Oximes; Radionuclide Imaging; Rats; Rats, Wistar; Technetium Tc 99m Exametazime

1997
The relationship between magnetic resonance diffusion imaging and autoradiographic markers of cerebral blood flow and hypoxia in an animal stroke model.
    Magnetic resonance in medicine, 1999, Volume: 41, Issue:4

    Topics: Animals; Autoradiography; Cell Hypoxia; Cerebrovascular Circulation; Cerebrovascular Disorders; Diffusion; Disease Models, Animal; Magnetic Resonance Imaging; Male; Nitroimidazoles; Rats; Rats, Wistar; Technetium Tc 99m Exametazime

1999
Clinical pharmacokinetics of 123I-IAZA in healthy volunteers.
    Nuclear medicine communications, 1999, Volume: 20, Issue:6

    Topics: Adult; Female; Half-Life; Humans; Hypoxia; Iodine Radioisotopes; Male; Middle Aged; Models, Biological; Nitroimidazoles; Radionuclide Imaging; Radiopharmaceuticals; Tissue Distribution

1999
Identification of hypoxic regions in traumatic brain injury.
    Clinical nuclear medicine, 1999, Volume: 24, Issue:11

    Topics: Brain Injuries; Humans; Hypoxia, Brain; Iodine Radioisotopes; Nitroimidazoles; Tomography, Emission-Computed, Single-Photon

1999
Effects of methoxyflurane anesthesia on the pharmacokinetics of 125I-IAZA in Sprague-Dawley rats.
    Nuclear medicine and biology, 1999, Volume: 26, Issue:8

    Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Area Under Curve; Biotransformation; Calibration; Chromatography, High Pressure Liquid; Half-Life; Iodine Radioisotopes; Isotope Labeling; Methoxyflurane; Nitroimidazoles; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Tissue Distribution

1999
Synthesis, radiolabeling, and biodistribution of putative metabolites of iodoazomycin arabinoside.
    Nuclear medicine and biology, 2000, Volume: 27, Issue:1

    Topics: Animals; Injections, Intravenous; Iodine Radioisotopes; Metabolic Clearance Rate; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Nitroimidazoles; Radionuclide Imaging; Tissue Distribution

2000
Dosimetry estimations for 123I-IAZA in healthy volunteers.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2001, Volume: 42, Issue:9

    Topics: Female; Gamma Cameras; Humans; Hypoxia; Iodine Radioisotopes; Male; Nitroimidazoles; Radiometry; Radionuclide Imaging; Radiopharmaceuticals; Tissue Distribution

2001
Synthesis of 1-beta-D-(5-deoxy-5-iodoarabinofuranosyl)-2-nitroimidazole (beta-IAZA): a novel marker of tissue hypoxia.
    Chemical & pharmaceutical bulletin, 2003, Volume: 51, Issue:4

    Topics: Biomarkers; Cell Hypoxia; Nitroimidazoles; Stereoisomerism

2003
A one-pot synthesis of 1-alpha- and 1-beta-D-arabinofuranosyl-2-nitroimidazoles: synthons to the markers of tumor hypoxia.
    Nucleosides, nucleotides & nucleic acids, 2005, Volume: 24, Issue:3

    Topics: Biomarkers, Tumor; Cell Hypoxia; Molecular Structure; Monosaccharides; Neoplasms; Nitroimidazoles

2005
[131I]Iodoazomycin arabinoside for low-dose-rate isotope radiotherapy: radiolabeling, stability, long-term whole-body clearance and radiation dosimetry estimates in mice.
    Nuclear medicine and biology, 2005, Volume: 32, Issue:6

    Topics: Animals; Cell Hypoxia; Cell Proliferation; Female; Humans; Iodine Radioisotopes; Mammary Neoplasms, Experimental; Metabolic Clearance Rate; Mice; Mice, Inbred BALB C; Nitroimidazoles; Radioimmunotherapy; Radiometry; Radiopharmaceuticals; Radiotherapy Dosage; Tetrazolium Salts; Thiazoles; Tissue Distribution; Tumor Cells, Cultured

2005
Design, synthesis, and preliminary biological evaluation of 6-O-glucose-azomycin adducts for diagnosis and therapy of hypoxic tumors.
    Journal of medicinal chemistry, 2012, Jul-12, Volume: 55, Issue:13

    Topics: Cell Hypoxia; Cell Line, Tumor; Drug Design; Glucose Transport Proteins, Facilitative; Glucosides; Glycosides; Humans; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Misonidazole; Neoplasms; Nitroimidazoles; Radiation-Sensitizing Agents; Radionuclide Imaging; Radiopharmaceuticals; Transcriptional Activation

2012
[131I]IAZA as a molecular radiotherapeutic (MRT) drug: wash-out with cold IAZA accelerates clearance in a murine tumor model.
    Current radiopharmaceuticals, 2013, Jun-06, Volume: 6, Issue:2

    Topics: Animals; Cold Temperature; Healthy Volunteers; Humans; Iodine Radioisotopes; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Nitroimidazoles; Radiopharmaceuticals; Tissue Distribution

2013
Galactose-based Thermosensitive Nanogels for Targeted Drug Delivery of Iodoazomycin Arabinofuranoside (IAZA) for Theranostic Management of Hypoxic Hepatocellular Carcinoma.
    Biomacromolecules, 2015, Jul-13, Volume: 16, Issue:7

    Topics: Carcinoma, Hepatocellular; Cell Hypoxia; Cell Line, Tumor; Cell Survival; Drug Delivery Systems; Galactose; HeLa Cells; Hep G2 Cells; Humans; Liver Neoplasms; MCF-7 Cells; Nanogels; Nitroimidazoles; Polyethylene Glycols; Polyethyleneimine; Radiation-Sensitizing Agents; Temperature; Theranostic Nanomedicine

2015