Page last updated: 2024-08-21

azomycin and allopurinol

azomycin has been researched along with allopurinol in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-199011 (44.00)18.7374
1990's2 (8.00)18.2507
2000's5 (20.00)29.6817
2010's6 (24.00)24.3611
2020's1 (4.00)2.80

Authors

AuthorsStudies
Gallerano, RH; Marr, JJ; Sosa, RR1
Argenbright, LS; Kedderis, GL; Miwa, GT1
Aldunate, J; Letelier, ME; Morello, A; Repetto, Y1
Beaulieu, BB; Chrystal, EJ; Goldman, P; Koch, RL; McLafferty, MA; Sudlow, G; Yeung, TC1
Gallerano, RH; Meirovich, CI; Montrull, HL; Sosa, RR1
Liu, SF; Raleigh, JA1
Derache, P; Derache, R; Massol, M1
Lu, AY; West, SB; Wislocki, PG; Wolf, FJ1
Clarke, ED; Goulding, KH; Wardman, P2
Josephy, PD; Palcic, B; Skarsgard, LD1
White, RA; Workman, P1
Chan, YW; Cyr, JE; Linder, KE; Malley, MF; Nowotnik, DP; Nunn, AD1
Gallerano, RR; Sosa, RR1
Colmenarez-Mendoza, HJ; Dávila-Spinetti, DF; Lobo-Vielma, L1
A, IZ; B, WA; G, IH; H, IN; H, MT; L, MI; M, LJ; P, JS; V, AM; V, PM1
Bartel, LC; Castro, JA; Montalto de Mecca, M1
Bestetti, RB; Theodoropoulos, TA1
Bartel, LC; Bietto, FM; Castro, JA; de Castro, CR; Montalto de Mecca, M1
Bua, J; Bustos, PL; Fichera, LE; Gonzalez, MN; Grosso, NL; Perrone, AE; Postan, M1
Albareda, MC; Alvarez, MG; Armenti, AH; Bertocchi, G; Cooley, G; Laucella, SA; Lococo, BE; Perez-Mazliah, DE; Petti, M; Tarleton, RL; Viotti, R1
Alarcon, ML; Bua, J; Fichera, LE; Grosso, NL; Laucella, SA; Riarte, A1
Benatar, AF; Búa, J; Esteva, MI; Fichera, LE; López Alarcón, M; Prado, NG; Rial, MS; Riarte, AR; Scalise, ML1
Assíria, T; Bahia, MT; Diniz, LF; Gonçalves, KR; Mazzeti, AL; Ribeiro, I; WonDollinger, RS1
Cardoso Santos, E; Dias Novaes, R; Lima, GDA; Oliveira Silva, R; Santana Nogueira, S; Vilela Gonçalves, R1

Reviews

3 review(s) available for azomycin and allopurinol

ArticleYear
[Biochemical bases of the action of anti-chagasic drugs].
    Archivos de biologia y medicina experimentales, 1988, Volume: 21, Issue:1

    Topics: Allopurinol; Animals; Free Radicals; Gentian Violet; Glutathione; Humans; Nifurtimox; Nitroimidazoles; Oxidation-Reduction; Trypanocidal Agents; Trypanosoma cruzi

1988
A systematic review of studies on heart transplantation for patients with end-stage Chagas' heart disease.
    Journal of cardiac failure, 2009, Volume: 15, Issue:3

    Topics: Allopurinol; Chagas Disease; Graft Rejection; Heart Transplantation; Humans; Immunosuppressive Agents; Neoplasms; Nitroimidazoles; Perioperative Care; Postoperative Complications; Recurrence; Trypanocidal Agents

2009
Monotherapy and combination chemotherapy for Chagas disease treatment: a systematic review of clinical efficacy and safety based on randomized controlled trials.
    Parasitology, 2022, Volume: 149, Issue:13

    Topics: Allopurinol; Chagas Disease; Drug Therapy, Combination; Humans; Nitroimidazoles; Randomized Controlled Trials as Topic; Treatment Outcome; Trypanocidal Agents; Trypanosoma cruzi

2022

Trials

3 trial(s) available for azomycin and allopurinol

ArticleYear
Therapeutic efficacy of allopurinol in patients with chronic Chagas' disease.
    The American journal of tropical medicine and hygiene, 1990, Volume: 43, Issue:2

    Topics: Adult; Allopurinol; Chagas Disease; Chronic Disease; Clinical Trials as Topic; Female; Humans; Male; Nifurtimox; Nitroimidazoles; Trypanocidal Agents

1990
[Allopurinol in the treatment of chronic Chagas' disease].
    Arquivos brasileiros de cardiologia, 1985, Volume: 45, Issue:3

    Topics: Allopurinol; Chagas Cardiomyopathy; Chagas Disease; Chronic Disease; Clinical Trials as Topic; Female; Humans; Male; Nifurtimox; Nitroimidazoles; Trypanocidal Agents

1985
Sequential combined treatment with allopurinol and benznidazole in the chronic phase of Trypanosoma cruzi infection: a pilot study.
    The Journal of antimicrobial chemotherapy, 2013, Volume: 68, Issue:2

    Topics: Adult; Allopurinol; Antiprotozoal Agents; B-Lymphocytes; Chagas Disease; Chronic Disease; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Middle Aged; Nitroimidazoles; Pilot Projects; T-Lymphocytes; Treatment Outcome; Trypanosoma cruzi

2013

Other Studies

19 other study(ies) available for azomycin and allopurinol

ArticleYear
Mechanism of reductive activation of a 5-nitroimidazole by flavoproteins: model studies with dithionite.
    Archives of biochemistry and biophysics, 1988, Volume: 262, Issue:1

    Topics: Animals; Chemical Phenomena; Chemistry; Dithionite; Liver; NADPH-Ferrihemoprotein Reductase; Nitroimidazoles; Nitroreductases; Rats; Rats, Inbred Strains; Ronidazole; Sulfites; Xanthine Oxidase

1988
Comparing the reduction of nitroimidazoles in bacteria and mammalian tissues and relating it to biological activity.
    Biochemical pharmacology, 1986, Jan-01, Volume: 35, Issue:1

    Topics: Animals; Bacteria, Anaerobic; Biotransformation; Cecum; DNA Repair; Enterobacteriaceae; Germ-Free Life; Humans; Metronidazole; Mutation; Nitroimidazoles; Oxidation-Reduction; Structure-Activity Relationship; Xanthine Oxidase

1986
Reductive fragmentation of 2-nitroimidazoles in the presence of nitroreductases--glyoxal formation from misonidazole.
    Biochemical pharmacology, 1983, Apr-15, Volume: 32, Issue:8

    Topics: Acetylcholinesterase; Animals; Cell Line; Cricetinae; Cricetulus; Female; Glyoxylates; L-Lactate Dehydrogenase; Misonidazole; Nitroimidazoles; Ovary; Xanthine Oxidase

1983
[Effects of nitroimidazole and nitrofuran derivatives on uric acid formation in an anaerobic environment by xanthine oxidase and microsomal nitroreductase].
    Annales pharmaceutiques francaises, 1983, Volume: 41, Issue:3

    Topics: Animals; In Vitro Techniques; Microsomes; Nitrofurans; Nitroimidazoles; Nitroreductases; Oxidoreductases; Rats; Rats, Inbred Strains; Uric Acid; Xanthine Oxidase

1983
Drug residue formation from ronidazole, a 5-nitroimidazole. II. Involvement of microsomal NADPH-cytochrome P-450 reductase in protein alkylation in vitro.
    Chemico-biological interactions, 1982, Volume: 41, Issue:3

    Topics: Alkylation; Anaerobiosis; Animals; Flavin Mononucleotide; Male; Methylcholanthrene; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Nitroimidazoles; Protein Binding; Rats; Ronidazole; Serum Albumin, Bovine; Xanthine Oxidase

1982
Anaerobic reduction of nitroimidazoles by reduced flavin mononucleotide and by xanthine oxidase.
    Biochemical pharmacology, 1980, Oct-01, Volume: 29, Issue:19

    Topics: Anaerobiosis; Electron Transport; Flavin Mononucleotide; Kinetics; Nitroimidazoles; Nitroso Compounds; Oxidation-Reduction; Xanthine Oxidase

1980
Reduction of misonidazole and its derivatives by xanthine oxidase.
    Biochemical pharmacology, 1981, Apr-15, Volume: 30, Issue:8

    Topics: Hypoxia; In Vitro Techniques; Misonidazole; Nitroimidazoles; Oxidation-Reduction; Xanthine Oxidase

1981
Effects of the xanthine oxidase inhibitor allopurinol on the renal clearance of nitroimidazoles.
    Biochemical pharmacology, 1982, Oct-01, Volume: 31, Issue:19

    Topics: Allopurinol; Animals; Kidney; Kinetics; Male; Metabolic Clearance Rate; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Misonidazole; Nitroimidazoles; Xanthine Oxidase

1982
Nitroimidazoles as anaerobic electron acceptors for xanthine oxidase.
    Biochemical pharmacology, 1982, Oct-15, Volume: 31, Issue:20

    Topics: Anaerobiosis; Chemical Phenomena; Chemistry, Physical; Electron Transport; Nitroimidazoles; Oxidation-Reduction; Time Factors; Xanthine Oxidase

1982
TcO(PnA.O-1-(2-nitroimidazole)) [BMS-181321], a new technetium-containing nitroimidazole complex for imaging hypoxia: synthesis, characterization, and xanthine oxidase-catalyzed reduction.
    Journal of medicinal chemistry, 1994, Jan-07, Volume: 37, Issue:1

    Topics: Chromatography, High Pressure Liquid; Crystallization; Crystallography, X-Ray; Dimethylformamide; Electrochemistry; Hypoxia; Kinetics; Magnetic Resonance Spectroscopy; Molecular Structure; Nitroimidazoles; Organotechnetium Compounds; Radionuclide Imaging; Stereoisomerism; Xanthine Oxidase

1994
[Interventional study in the natural evolution of Chagas disease. Evaluation of specific antiparasitic treatment. Retrospective-prospective study of antiparasitic therapy].
    Revista de la Facultad de Ciencias Medicas (Cordoba, Argentina), 2000, Volume: 57, Issue:2

    Topics: Adolescent; Adult; Aged; Allopurinol; Antiprotozoal Agents; Chagas Cardiomyopathy; Chagas Disease; Female; Follow-Up Studies; Humans; Male; Middle Aged; Nifurtimox; Nitroimidazoles; Prospective Studies; Retrospective Studies; Time Factors; Treatment Outcome; Trypanocidal Agents

2000
[Mechanisms responsible for myocardial damage progression in chronic Chagas' disease].
    Revista espanola de cardiologia, 2005, Volume: 58, Issue:9

    Topics: Allopurinol; Antimetabolites; Chagas Cardiomyopathy; Disease Progression; Double-Blind Method; Drug Therapy, Combination; Echocardiography; Electrocardiography; Follow-Up Studies; Humans; Nitroimidazoles; Prognosis; Randomized Controlled Trials as Topic; Risk Factors; Time Factors; Trypanocidal Agents

2005
[Part VI. Antiparasitic treatment for Chagas disease].
    Revista chilena de infectologia : organo oficial de la Sociedad Chilena de Infectologia, 2008, Volume: 25, Issue:5

    Topics: Allopurinol; Animals; Chagas Disease; Follow-Up Studies; Humans; Immunocompromised Host; Immunosuppressive Agents; Nifurtimox; Nitroimidazoles; Trypanocidal Agents; Trypanosoma cruzi

2008
Nitroreductive metabolic activation of some carcinogenic nitro heterocyclic food contaminants in rat mammary tissue cellular fractions.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2009, Volume: 47, Issue:1

    Topics: Allopurinol; Animals; Carcinogens; Female; Food Contamination; Hypoxanthine; Mammary Glands, Animal; Molecular Structure; NADP; Nitrofurans; Nitroimidazoles; Nitroreductases; Oxidation-Reduction; Rats; Rats, Sprague-Dawley

2009
Metabolization of nifurtimox and benznidazole in cellular fractions of rat mammary tissue.
    Human & experimental toxicology, 2010, Volume: 29, Issue:10

    Topics: Allopurinol; Animals; Cell Fractionation; Chromatography, High Pressure Liquid; Female; Lipid Peroxidation; Mammary Glands, Animal; Microscopy, Electron, Transmission; Microsomes; Nifurtimox; Nitroimidazoles; Nitroreductases; Protein Carbonylation; Rats; Rats, Sprague-Dawley; Sulfhydryl Compounds; Trypanocidal Agents

2010
Trypanosoma cruzi: biological characterization of a isolate from an endemic area and its susceptibility to conventional drugs.
    Experimental parasitology, 2010, Volume: 126, Issue:2

    Topics: Allopurinol; Animals; Cell Line; Cells, Cultured; Chagas Disease; Endemic Diseases; Inhibitory Concentration 50; Insect Vectors; Mice; Mice, Inbred C3H; Muscle Cells; Muscles; Nicaragua; Nitroimidazoles; Phylogeny; Rats; Triatoma; Trypanocidal Agents; Trypanosoma cruzi

2010
Combined treatment with benznidazole and allopurinol in mice infected with a virulent Trypanosoma cruzi isolate from Nicaragua.
    Parasitology, 2013, Volume: 140, Issue:10

    Topics: Allopurinol; Animals; Antibodies, Protozoan; Chagas Disease; Disease Models, Animal; Drug Therapy, Combination; Mice; Nicaragua; Nitroimidazoles; Survival Analysis; Treatment Outcome; Trypanosoma cruzi

2013
Experimental combination therapy using low doses of benznidazole and allopurinol in mouse models of Trypanosoma cruzi chronic infection.
    Parasitology, 2019, Volume: 146, Issue:3

    Topics: Allopurinol; Animals; Chagas Disease; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Nitroimidazoles; Random Allocation; Specific Pathogen-Free Organisms; Trypanocidal Agents; Trypanosoma cruzi

2019
Synergic Effect of Allopurinol in Combination with Nitroheterocyclic Compounds against Trypanosoma cruzi.
    Antimicrobial agents and chemotherapy, 2019, Volume: 63, Issue:6

    Topics: Allopurinol; Animals; Cell Line; Chagas Disease; Humans; Mice; Mortality; Nifurtimox; Nitroimidazoles; Real-Time Polymerase Chain Reaction; Trypanosoma cruzi

2019