Compounds > azomycin
Page last updated: 2024-08-21

azomycin and 18f-faza

azomycin has been researched along with 18f-faza in 80 studies

Research

Studies (80)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's17 (21.25)29.6817
2010's56 (70.00)24.3611
2020's7 (8.75)2.80

Authors

AuthorsStudies
Beck, R; Kumar, P; Machulla, HJ; McEwan, AJ; Picchio, M; Piert, M; Reischl, G; Schwaiger, M; Wester, HJ; Wiebe, LI; Ziegler, S1
Bieg, C; Ehrlichmann, W; Kumar, P; Machulla, HJ; Reischl, G; Solbach, C; Wiebe, LI1
Binns, D; Cullinane, C; Hicks, RJ; McArthur, GA; Roselt, P; Solomon, B; Weibe, LI1
Beck, R; Grosu, AL; Krause, BJ; Machulla, HJ; Picchio, M; Piert, M; Reischl, G; Röper, B; Souvatzoglou, M; Wester, HJ1
Mankoff, DA; Rajendran, JG1
Andratschke, N; Beck, R; Carlsen, JM; Huisman, MC; Lebschi, JA; Machulla, HJ; Picchio, M; Piert, M; Röper, B; Souvatzoglou, M1
Dobritz, M; Grosu, AL; Jacob, V; Machulla, HJ; Molls, M; Piert, M; Reischl, G; Röper, B; Schwaiger, M; Souvatzoglou, M; Wester, HJ; Wiedenmann, N1
Busk, M; Bussink, J; Horsman, MR; Jakobsen, S; Keiding, S; Overgaard, J; van der Kogel, AJ1
Beck, R; Haubner, R; Johnson, TD; Machulla, HJ; Picchio, M; Piert, M; Reischl, G; Schwaiger, M; Seidl, S; Wester, HJ1
Eschmann, SM; Langen, KJ1
Busk, M; Horsman, MR; Overgaard, J1
Busk, M; Bussink, J; Horsman, MR; Jakobsen, S; Overgaard, J; van der Kogel, A1
Boerman, OC; Bussink, J; Kaanders, JH; Laverman, P; Oyen, WJ; Troost, EG1
Emami, S; Kresolek, Z; Kumar, P; McEwan, AJ; Wiebe, LI; Yang, J1
Abrams, DN; Kumar, P; McEwan, AJ; Postema, EJ; Riauka, TA; Richmond, DA; Wiebe, LI1
Busk, M; Bussink, J; Hansen, KV; Horsman, MR; Jakobsen, S; Overgaard, J; van der Kogel, A1
Bennewith, KL; Cairns, RA; Chang, DT; Denko, NC; Giaccia, AJ; Graves, EE1
Kumar, P; McEwan, AJ; Naimi, E; Wiebe, LI1
Nandy, SK; Rajan, MG1
Astner, ST; Nüsslin, F; Shi, K; Souvatzoglou, M; Vaupel, P; Wilkens, JJ; Ziegler, SI1
Busk, M; Horsman, MR; Jakobsen, S; Munk, OL; Overgaard, J; Skals, M; Steiniche, T; Wang, T1
Bachtiary, B; Dimopoulos, J; Dudczak, R; Georg, D; Karanikas, G; Kletter, K; Kommata, S; Lukic, D; Pötter, R; Schmid, MP; Schuetz, M1
Chitneni, SK; Dewhirst, MW; Palmer, GM; Zalutsky, MR1
Alsner, J; Busk, M; Horsman, MR; Jakobsen, S; Overgaard, J; Sørensen, BS; Toustrup, K1
Bouvet, VR; Wiebe, LI; Wuest, F; Wuest, M1
Aki, H; Fukumura, T; Furutsuka, K; Hayashi, K; Muto, M; Nakao, R; Suzuki, K; Takei, M1
Busk, M; Horsman, MR; Jakobsen, S; Mortensen, LS; Nordsmark, M; Overgaard, J; Theil, J1
Bezak, E; Filip, SM; Marcu, LG1
Desmond, T; Garcia-Parra, R; Hussain, H; Meyer, C; Park, H; Piert, M; Shah, RB; Siddiqui, J; Wood, D1
Bukala, D; Cay, F; Judenhofer, MS; Kneilling, M; Machulla, HJ; Maier, FC; Pichler, BJ; Reischl, G; Röcken, M; Schmid, A1
Cheeseman, C; Khlebnikov, V; Kumar, P; Liang, H; Shustov, G; Wiebe, LI; Yang, XH; Zheng, W1
Busk, M; D'Andrea, FP; Hansen, KV; Horsman, MR; Jakobsen, S; Kallehauge, JF; Mortensen, LS; Nordsmark, M; Overgaard, J; Steiniche, T; Theil, J1
Alsner, J; Busk, M; Jakobsen, S; Johansen, J; Kallehauge, J; Lassen, P; Mortensen, LS; Nordsmark, M; Overgaard, J; Petersen, H; Petersen, J; Primdahl, H; Sørensen, BS; Theil, J; Toustrup, K1
Bender, D; Havelund, BM; Holdgaard, PC; Jakobsen, A; Mortensen, LS; Pløen, J; Rafaelsen, SR; Spindler, KL; Theil, J1
Dierckx, RA; Halmos, GB; Langedijk, JA; Pruim, J; Roodenburg, JL; van der Laan, BF; Wedman, J1
Belloli, S; Di Grigoli, G; Fazio, F; Masiello, V; Monterisi, C; Moresco, RM; Picchio, M; Sanvito, F; Valtorta, S1
Bahce, I; Boellaard, R; Lammertsma, AA; Raijmakers, P; Schuit, RC; Smit, EF; van Velden, FH; Verwer, EE; Windhorst, AD; Yaqub, M1
Bollineni, VR; de Groot, EH; Groen, HJ; Kerner, GS; Koole, MJ; Langendijk, JA; Luurtsema, G; Pruim, J; Steenbakkers, RJ; Widder, J; Wiegman, EM; Willemsen, AT1
Ball, D; Binns, D; Blum, R; Bressel, M; Callahan, J; Eu, P; Hicks, RJ; MacManus, MP; Rischin, D; Roselt, P; Segard, T; Trinkaus, ME1
Belloli, S; Brioschi, A; Calderoni, S; Fazio, F; Mauro, A; Monterisi, C; Moresco, RM; Pagani, A; Politi, LS; Raccagni, I; Ronchetti, F; Zara, G; Zenga, F1
Bruine de Bruin, L; Halmos, GB; Langendijk, JA; Pruim, J; Steenbakkers, RJ; van der Laan, BF1
Bol, A; Differding, S; Grégoire, V; Hanin, FX; Labar, D; Lee, JA; Servagi-Vernat, S1
Gupta, AK; Kumar, P; Ortlieb, R; Wiebe, LI1
Giraud, P; Servagi-Vernat, S1
Balkay, L; Emri, M; Goda, K; Juhász, I; Krasznai, Z; Krasznai, ZT; Lajtos, I; Márián, T; Mikecz, P; Miklovicz, T; Németh, E; Szabó, G; Szalóki, G; Trencsényi, G1
Bahce, I; Boellaard, R; Hoekstra, OS; Lammertsma, AA; Raijmakers, P; Schuit, RC; Smit, EF; van Velden, FH; Verwer, EE; Windhorst, AD; Yaqub, M1
Berndorff, D; Chang, E; Cheng, Z; Ellinghaus, P; Gambhir, SS; Gekeler, V; Liu, H; Liu, S; Unterschemmann, K1
Bol, A; Bol, V; Gallez, B; Grégoire, V; Jordan, B; Karroum, O; Labar, D; Tran, LB1
Bollineni, VR; Brouwer, CL; Groen, HJ; Halmos, GB; Koole, MJ; Langendijk, JA; Oosting, SF; Pruim, J; Steenbakkers, RJ; Vlasman, R; Widder, J; Wiegman, EM1
Dubois, L; Eriksson, J; Lambin, P; Lieuwes, NG; Peeters, SG; van Dongen, GA; van Elmpt, W; Zegers, CM1
de Waal, EG; Kluin, PM; Leene, MJ; Slart, RH; Vellenga, E1
Bol, A; Differding, S; Grégoire, V; Hanin, FX; Labar, D; Lee, JA; Servagi-Vernat, S; Sterpin, E1
Bol, A; Cao-Pham, TT; Gallez, B; Grégoire, V; Jordan, B; Labar, D; Tran, LB1
Bukala, D; Eichner, M; Feger, M; Fuchs, K; Harant, M; Kneilling, M; Lang, F; Mahling, M; Maier, FC; Pichler, BJ; Reischl, G; Reutershan, J; Thaiss, WM1
Mönnich, D; Thorwarth, D; Troost, EG; van Elmpt, W; Wack, LJ; Zegers, CM; Zips, D1
Bollineni, VR; Bruine de Bruin, L; de Bock, GH; Halmos, GB; Langendijk, JA; Pruim, J; Schuuring, E; Slagter-Menkema, L; Steenbakkers, RJ; van der Laan, BF; van der Wal, JE; van Hemel, BM; Wachters, JE1
Horiike, A; Inubushi, M; Koizumi, M; Nishio, M; Ohyanagi, F; Saga, T; Tanimoto, K; Yanagitani, N; Yoshikawa, K; Zhang, MR1
Binns, D; Bressel, M; Graves, EE; Hicks, RJ; Le, QT; Peters, L; Rischin, D; Young, RJ1
Bahce, I; Boellaard, R; de Langen, AJ; Hoekstra, OS; Huisman, MC; Iqbal, R; Kramer, GM; Lammertsma, AA; van Velden, FH; Verwer, EE; Windhorst, AD1
Fujibayashi, Y; Harada, R; Inubushi, M; Koizumi, M; Obata, T; Saga, T; Tanimoto, K; Uno, T; Yoshikawa, K; Zhang, MR1
Asamura, H; Fujii, H; Hayashi, Y; Kamiyama, I; Kinoshita, T; Ohtsuka, T1
Yoshimoto, M1
Dhani, NC; Green, D; Hedley, DW; Jaffray, D; Metran-Nascente, C; Metser, U; Milosevic, M; Vines, DC; Yeung, I1
Beiki, D; Binns, D; Cullinane, C; Ehrlichmann, W; Hicks, R; Kumar, P; Machulla, HJ; Naimi, E; Reischl, G; Roselt, P; Wiebe, LI; Yang, J1
Bol, A; Di Perri, D; Geets, X; Hanin, FX; Janssens, G; Labar, D; Lee, JA; Robert, A; Sterpin, E2
Bettinardi, V; Compierchio, A; Doglioni, C; Fallanca, F; Gianolli, L; Incerti, E; Mapelli, P; Masiello, V; Negri, G; Picchio, M; Rossetti, F1
Anzalone, N; Bettinardi, V; Conte, GM; Di Muzio, N; Fallanca, F; Gianolli, L; Incerti, E; Mapelli, P; Picchio, M; Zerbetto, F1
Bettinardi, V; Coliva, A; Compierchio, A; Doglioni, C; Fallanca, F; Gianolli, L; Incerti, E; Mapelli, P; Negri, G; Picchio, M; Rossetti, F; Savi, A1
Brans, B; Ceelen, W; De Vlieghere, E; De Vos, F; De Wever, O; Descamps, B; Goethals, I; Kersemans, K; Melsens, E; Pattyn, P; Vanhove, C1
Brocks, DR; Jans, HS; Kumar, P; Wiebe, LI; Wuest, M; Yang, XH1
Akbari, A; Falzon, C; Kumar, P; Naimi, E; Sun, W; Tandon, M; Wiebe, LI1
Bolcaen, J; Boterberg, T; De Meulenaere, V; De Vos, F; Deblaere, K; Descamps, B; Donche, S; Goethals, I; Kalala, JP; Kersemans, K; Van den Broecke, C; Vanhove, C; Verhoeven, J1
Bernards, N; De Souza, R; Fitzgerald, JB; Fricke, IB; Hendriks, BS; Klinz, SG; Lee, H; Ventura, M; Zheng, J1
Harada, R; Imaizumi, A; Inubushi, M; Kershaw, J; Koizumi, M; Obata, T; Saga, T; Tachibana, Y; Tanimoto, K; Uno, T; Yoshikawa, K; Zhang, MR1
Belly-Poinsignon, A; Champion, L; Madar, O; Mammar, H; Provost, C1
Anzalone, N; Barbera, M; Bettinardi, V; Castellano, A; Fallanca, F; Gianolli, L; Incerti, E; Mapelli, P; Picchio, M; Scifo, P1
Bernardi, R; Bertini, R; Bettinardi, V; Capitanio, U; Cascinu, S; Doglioni, C; Gianolli, L; Incerti, E; Larcher, A; Lucianò, R; Mapelli, P; Monterisi, C; Montorsi, F; Necchi, A; Pepe, G; Picchio, M; Salonia, A; Trevisani, F1
Anzalone, N; Bailo, M; Bettinardi, V; Callea, M; Castellano, A; Conte, GM; Fallanca, F; Gianolli, L; Incerti, E; Mapelli, P; Monterisi, C; Picchio, M; Rancoita, PMV; Scifo, P; Terreni, M; Vuozzo, M1
Bruce, J; Cairns, R; Chaudary, N; Croke, J; D'Souza, D; Dhani, N; Fyles, A; Han, K; Jaffray, D; Koritzinsky, M; Lee, TY; Metser, U; Milosevic, M; Pakbaz, S; Pintilie, M; Rouzbahman, M; Shek, T; Vines, D1

Reviews

6 review(s) available for azomycin and 18f-faza

ArticleYear
Molecular imaging of hypoxia.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2011, Volume: 52, Issue:2

    Topics: Humans; Hypoxia; Misonidazole; Neoplasms; Neovascularization, Pathologic; Nitroimidazoles; Positron-Emission Tomography; Radiography; Radiopharmaceuticals

2011
The role of PET imaging in overcoming radiobiological challenges in the treatment of advanced head and neck cancer.
    Cancer treatment reviews, 2012, Volume: 38, Issue:3

    Topics: Carcinoma, Squamous Cell; Cell Hypoxia; Cell Proliferation; Fluorine Radioisotopes; Head and Neck Neoplasms; Humans; Nitroimidazoles; Positron-Emission Tomography; Radioisotopes; Radiotherapy, Image-Guided; Squamous Cell Carcinoma of Head and Neck

2012
Alternative PET tracers in head and neck cancer. A review.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2013, Volume: 270, Issue:10

    Topics: Amino Acids; Antibodies, Monoclonal; Carbon Radioisotopes; Carcinoma, Squamous Cell; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Head and Neck Neoplasms; Humans; Misonidazole; Nitroimidazoles; Nucleosides; Positron-Emission Tomography; Radiopharmaceuticals

2013
Head and neck tumor hypoxia imaging by 18F-fluoroazomycin-arabinoside (18F-FAZA)-PET: a review.
    Clinical nuclear medicine, 2014, Volume: 39, Issue:1

    Topics: Animals; Cell Hypoxia; Cell Transformation, Neoplastic; Head and Neck Neoplasms; Humans; Nitroimidazoles; Positron-Emission Tomography

2014
[Metabolic tailoring in radiotherapy for head and neck cancer].
    Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 2014, Volume: 18, Issue:5-6

    Topics: Carcinoma, Squamous Cell; Cell Hypoxia; Clinical Trials as Topic; Diffusion Magnetic Resonance Imaging; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Head and Neck Neoplasms; Humans; Image Interpretation, Computer-Assisted; Magnetic Resonance Imaging; Misonidazole; Multimodal Imaging; Nitroimidazoles; Positron-Emission Tomography; Radiopharmaceuticals; Radiotherapy Dosage; Radiotherapy Planning, Computer-Assisted; Radiotherapy, Image-Guided; Tumor Burden

2014
[Current Status and Prospects on PET Radiopharmaceuticals for Radiotherapy].
    Igaku butsuri : Nihon Igaku Butsuri Gakkai kikanshi = Japanese journal of medical physics : an official journal of Japan Society of Medical Physics, 2015, Volume: 35, Issue:1

    Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Coordination Complexes; Fluorine Radioisotopes; Humans; Hypoxia; Misonidazole; Neoplasms; Nitroimidazoles; Organometallic Compounds; Phenylalanine; Positron-Emission Tomography; Radiopharmaceuticals; Thiosemicarbazones

2015

Trials

8 trial(s) available for azomycin and 18f-faza

ArticleYear
Initial results of hypoxia imaging using 1-alpha-D: -(5-deoxy-5-[18F]-fluoroarabinofuranosyl)-2-nitroimidazole ( 18F-FAZA).
    European journal of nuclear medicine and molecular imaging, 2009, Volume: 36, Issue:10

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Female; Fluorine Radioisotopes; Glioma; Head and Neck Neoplasms; Humans; Hypoxia; Lung Neoplasms; Lymphoma; Male; Middle Aged; Neoplasms; Nitroimidazoles; Positron-Emission Tomography; Radiopharmaceuticals; Young Adult

2009
Evaluating repetitive 18F-fluoroazomycin-arabinoside (18FAZA) PET in the setting of MRI guided adaptive radiotherapy in cervical cancer.
    Acta oncologica (Stockholm, Sweden), 2010, Volume: 49, Issue:7

    Topics: Adaptation, Biological; Adenocarcinoma; Adult; Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Female; Humans; Magnetic Resonance Imaging; Middle Aged; Nitroimidazoles; Periodicity; Pilot Projects; Positron-Emission Tomography; Radiography; Radiotherapy Dosage; Radiotherapy, Computer-Assisted; Uterine Cervical Neoplasms

2010
FAZA PET/CT hypoxia imaging in patients with squamous cell carcinoma of the head and neck treated with radiotherapy: results from the DAHANCA 24 trial.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2012, Volume: 105, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Cell Hypoxia; Female; Head and Neck Neoplasms; Humans; Lymph Nodes; Male; Middle Aged; Multimodal Imaging; Nitroimidazoles; Positron-Emission Tomography; Prognosis; Tomography, X-Ray Computed

2012
Imaging of hypoxia with 18F-FAZA PET in patients with locally advanced non-small cell lung cancer treated with definitive chemoradiotherapy.
    Journal of medical imaging and radiation oncology, 2013, Volume: 57, Issue:4

    Topics: Aged; Aged, 80 and over; Carcinoma, Non-Small-Cell Lung; Cell Hypoxia; Chemoradiotherapy; Female; Humans; Lung Neoplasms; Male; Middle Aged; Nitroimidazoles; Positron-Emission Tomography; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity; Treatment Outcome

2013
Hypoxia-guided adaptive radiation dose escalation in head and neck carcinoma: a planning study.
    Acta oncologica (Stockholm, Sweden), 2015, Volume: 54, Issue:7

    Topics: Aged; Carcinoma, Squamous Cell; Dose Fractionation, Radiation; Female; Head and Neck Neoplasms; Humans; Image Interpretation, Computer-Assisted; Male; Middle Aged; Multimodal Imaging; Nitroimidazoles; Positron-Emission Tomography; Radiopharmaceuticals; Radiotherapy Planning, Computer-Assisted; Squamous Cell Carcinoma of Head and Neck; Tomography, X-Ray Computed

2015
Prognostic value of (18) F-fluoroazomycin arabinoside PET/CT in patients with advanced non-small-cell lung cancer.
    Cancer science, 2015, Volume: 106, Issue:11

    Topics: Adult; Aged; Carcinoma, Non-Small-Cell Lung; Disease-Free Survival; Female; Fluorodeoxyglucose F18; Humans; Kaplan-Meier Estimate; Lung Neoplasms; Male; Middle Aged; Multimodal Imaging; Nitroimidazoles; Positron-Emission Tomography; Prognosis; Proportional Hazards Models; Radiopharmaceuticals; Tomography, X-Ray Computed

2015
Prognostic value of PET/CT with (18)F-fluoroazomycin arabinoside for patients with head and neck squamous cell carcinomas receiving chemoradiotherapy.
    Annals of nuclear medicine, 2016, Volume: 30, Issue:3

    Topics: Carcinoma, Squamous Cell; Chemoradiotherapy; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Nitroimidazoles; Positron Emission Tomography Computed Tomography; Prognosis; Squamous Cell Carcinoma of Head and Neck

2016
A Phase II Randomized Trial of Chemoradiation with or without Metformin in Locally Advanced Cervical Cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2022, 12-15, Volume: 28, Issue:24

    Topics: COVID-19; Female; Humans; Hypoxia; Metformin; Nitroimidazoles; Pandemics; Positron Emission Tomography Computed Tomography; Positron-Emission Tomography; Radiopharmaceuticals; Uterine Cervical Neoplasms

2022

Other Studies

66 other study(ies) available for azomycin and 18f-faza

ArticleYear
Hypoxia-specific tumor imaging with 18F-fluoroazomycin arabinoside.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2005, Volume: 46, Issue:1

    Topics: Animals; Cell Hypoxia; Disease Models, Animal; Female; Metabolic Clearance Rate; Mice; Mice, Inbred BALB C; Mice, Nude; Misonidazole; Neoplasms; Nitroimidazoles; Organ Specificity; Oxidation-Reduction; Oxygen; Radionuclide Imaging; Radiopharmaceuticals; Tissue Distribution

2005
Preparation of the hypoxia imaging PET tracer [18F]FAZA: reaction parameters and automation.
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2005, Volume: 62, Issue:6

    Topics: Automation; Cell Hypoxia; Fluorine Radioisotopes; Nitroimidazoles; Positron-Emission Tomography; Radioisotopes

2005
Modulation of intratumoral hypoxia by the epidermal growth factor receptor inhibitor gefitinib detected using small animal PET imaging.
    Molecular cancer therapeutics, 2005, Volume: 4, Issue:9

    Topics: Animals; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; ErbB Receptors; Fluorine Radioisotopes; Gefitinib; Humans; Hypoxia; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Nitroimidazoles; Oxidation-Reduction; Oxygen; Positron-Emission Tomography; Quinazolines; Tissue Distribution

2005
Tumour hypoxia imaging with [18F]FAZA PET in head and neck cancer patients: a pilot study.
    European journal of nuclear medicine and molecular imaging, 2007, Volume: 34, Issue:10

    Topics: Aged; Cell Hypoxia; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Nitroimidazoles; Oxygen; Pilot Projects; Positron-Emission Tomography; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity

2007
Beyond detection: novel applications for PET imaging to guide cancer therapy.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2007, Volume: 48, Issue:6

    Topics: Animals; Antineoplastic Agents; Cell Hypoxia; Fluorine Radioisotopes; Head and Neck Neoplasms; Humans; Mammary Neoplasms, Experimental; Nitroimidazoles; Positron-Emission Tomography; Radiation-Sensitizing Agents; Tirapazamine; Triazines

2007
Pretreatment 18F-FAZA PET predicts success of hypoxia-directed radiochemotherapy using tirapazamine.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2007, Volume: 48, Issue:6

    Topics: Animals; Antineoplastic Agents; Cell Hypoxia; Cell Line, Tumor; Combined Modality Therapy; Female; Fluorine Radioisotopes; Mammary Neoplasms, Experimental; Mice; Mice, Nude; Neoplasm Transplantation; Nitroimidazoles; Positron-Emission Tomography; Radiation-Sensitizing Agents; Radiopharmaceuticals; Tirapazamine; Transplantation, Heterologous; Triazines; Whole Body Imaging

2007
Hypoxia imaging with FAZA-PET and theoretical considerations with regard to dose painting for individualization of radiotherapy in patients with head and neck cancer.
    International journal of radiation oncology, biology, physics, 2007, Oct-01, Volume: 69, Issue:2

    Topics: Aged; Carcinoma, Squamous Cell; Cell Hypoxia; Feasibility Studies; Female; Fluorine Radioisotopes; Head and Neck Neoplasms; Humans; Male; Middle Aged; Nitroimidazoles; Positron-Emission Tomography; Radiotherapy, Intensity-Modulated; Tomography, X-Ray Computed

2007
Imaging hypoxia in xenografted and murine tumors with 18F-fluoroazomycin arabinoside: a comparative study involving microPET, autoradiography, PO2-polarography, and fluorescence microscopy.
    International journal of radiation oncology, biology, physics, 2008, Mar-15, Volume: 70, Issue:4

    Topics: Animals; Autoradiography; Carcinoma, Squamous Cell; Cell Hypoxia; Female; Fibrosarcoma; Fluorine Radioisotopes; Immunocompromised Host; Immunohistochemistry; Mice; Mice, Inbred C3H; Mice, Nude; Microscopy, Fluorescence; Nitroimidazoles; Oxygen; Polarography; Positron-Emission Tomography; Radiation-Sensitizing Agents; Transplantation, Heterologous

2008
Intratumoral spatial distribution of hypoxia and angiogenesis assessed by 18F-FAZA and 125I-Gluco-RGD autoradiography.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2008, Volume: 49, Issue:4

    Topics: Animals; Autoradiography; Cell Hypoxia; Female; Fluorine Radioisotopes; Glucosides; Hypoxia-Inducible Factor 1, alpha Subunit; Immunohistochemistry; Iodine Radioisotopes; Mice; Neoplasms, Experimental; Neovascularization, Pathologic; Nitroimidazoles; Oligopeptides; Radionuclide Imaging

2008
Correlative imaging of hypoxia and angiogenesis in oncology.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2008, Volume: 49, Issue:4

    Topics: Autoradiography; Cell Hypoxia; Glucosides; Humans; Neoplasms; Neovascularization, Pathologic; Nitroimidazoles; Oligopeptides; Positron-Emission Tomography

2008
Resolution in PET hypoxia imaging: voxel size matters.
    Acta oncologica (Stockholm, Sweden), 2008, Volume: 47, Issue:7

    Topics: Animals; Carcinoma, Squamous Cell; Cell Hypoxia; Mice; Mice, Nude; Microscopy, Fluorescence; Necrosis; Neoplasms, Experimental; Nitroimidazoles; Positron-Emission Tomography

2008
Cellular uptake of PET tracers of glucose metabolism and hypoxia and their linkage.
    European journal of nuclear medicine and molecular imaging, 2008, Volume: 35, Issue:12

    Topics: Animals; Binding, Competitive; Biological Transport; Cell Count; Cell Line, Tumor; Female; Fluorodeoxyglucose F18; Glucose; Humans; Hypoxia; Mice; Neoplasms; Nitroimidazoles; Oxygen; Positron-Emission Tomography; Time Factors

2008
Intratumoral spatial distribution of hypoxia and angiogenesis assessed by 18F-FAZA and 125I-gluco-RGD autoradiography.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2008, Volume: 49, Issue:10

    Topics: Animals; Diagnostic Imaging; Glucosides; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Iodine Radioisotopes; Mice; Neoplasm Transplantation; Neovascularization, Pathologic; Nitroimidazoles; Oligopeptides; Radiopharmaceuticals; Research Design

2008
Synthesis and hypoxia selective radiosensitization potential of beta-2-FAZA and beta-3-FAZL: fluorinated azomycin beta-nucleosides.
    Medicinal chemistry (Shariqah (United Arab Emirates)), 2009, Volume: 5, Issue:2

    Topics: Fluorine Radioisotopes; HCT116 Cells; Humans; Hydrophobic and Hydrophilic Interactions; Magnetic Resonance Spectroscopy; Molecular Structure; Nitroimidazoles; Nucleosides; Radiation Tolerance; Radiation-Sensitizing Agents

2009
Can hypoxia-PET map hypoxic cell density heterogeneity accurately in an animal tumor model at a clinically obtainable image contrast?
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2009, Volume: 92, Issue:3

    Topics: Animals; Carcinoma, Squamous Cell; Cell Count; Cell Hypoxia; Disease Models, Animal; Female; Hypoxia; Mice; Mice, Inbred C3H; Nitroimidazoles; Oxygen; Positron-Emission Tomography; Radiopharmaceuticals; Random Allocation; Sensitivity and Specificity; Tissue Distribution

2009
Pharmacologically increased tumor hypoxia can be measured by 18F-Fluoroazomycin arabinoside positron emission tomography and enhances tumor response to hypoxic cytotoxin PR-104.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2009, Dec-01, Volume: 15, Issue:23

    Topics: Animals; Cell Hypoxia; Cell Line, Tumor; Dose-Response Relationship, Drug; Fluorine Radioisotopes; Humans; Mice; Mice, Nude; Mitochondria; Neoplasm Transplantation; Neoplasms; Nitrogen Mustard Compounds; Nitroimidazoles; Oxygen Consumption; Positron-Emission Tomography; Radiopharmaceuticals

2009
Synthesis, radiofluorination, and hypoxia-selective studies of FRAZ: A configurational and positional analogue of the clinical hypoxia marker, [18F]-FAZA.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antineoplastic Agents; Binding Sites; Biomarkers, Tumor; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Drug Screening Assays, Antitumor; Fluorine Radioisotopes; Humans; Hypoxia; Isotope Labeling; Nitroimidazoles; Positron-Emission Tomography; Ribose

2010
Simple, column purification technique for the fully automated radiosynthesis of [18F]fluoroazomycinarabinoside ([18F]FAZA).
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2010, Volume: 68, Issue:10

    Topics: Automation; Chromatography; Fluorine Radioisotopes; Isotope Labeling; Methods; Nitroimidazoles; Radiation-Sensitizing Agents; Radiopharmaceuticals

2010
Quantitative assessment of hypoxia kinetic models by a cross-study of dynamic 18F-FAZA and 15O-H2O in patients with head and neck tumors.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2010, Volume: 51, Issue:9

    Topics: Adult; Cell Hypoxia; Feasibility Studies; Female; Head and Neck Neoplasms; Humans; Kinetics; Male; Middle Aged; Models, Biological; Nitroimidazoles; Oxygen Radioisotopes; Positron-Emission Tomography; Reproducibility of Results; Water

2010
Assessing hypoxia in animal tumor models based on pharmocokinetic analysis of dynamic FAZA PET.
    Acta oncologica (Stockholm, Sweden), 2010, Volume: 49, Issue:7

    Topics: Animals; Carcinoma, Squamous Cell; Female; Gingival Neoplasms; Humans; Hypoxia; Mice; Mice, Inbred C3H; Neoplasm Transplantation; Neoplasms; Nitroimidazoles; Positron-Emission Tomography; Transplantation, Heterologous; Tumor Cells, Cultured; Uterine Cervical Neoplasms

2010
In vivo identification and specificity assessment of mRNA markers of hypoxia in human and mouse tumors.
    BMC cancer, 2011, Feb-09, Volume: 11

    Topics: Animals; Biomarkers, Tumor; Carbonic Anhydrases; Cell Line, Tumor; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glucose Transporter Type 1; Humans; Hypoxia; Mice; Mice, Inbred C3H; Mice, Inbred Strains; Mice, Nude; Neoplasms, Experimental; Nitroimidazoles; Positron-Emission Tomography; Protein-Lysine 6-Oxidase; Reproducibility of Results; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transplantation, Heterologous

2011
Synthesis of hypoxia imaging agent 1-(5-deoxy-5-fluoro-α-D-arabinofuranosyl)-2-nitroimidazole using microfluidic technology.
    Nuclear medicine and biology, 2011, Volume: 38, Issue:2

    Topics: Animals; Cell Hypoxia; Cell Line, Tumor; Female; Mice; Mice, Inbred BALB C; Microfluidic Analytical Techniques; Neoplasms; Nitroimidazoles; Positron-Emission Tomography; Radiochemistry; Ribose

2011
High-yield automated synthesis of [18F]fluoroazomycin arabinoside ([18F]FAZA) for hypoxia-specific tumor imaging.
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2011, Volume: 69, Issue:7

    Topics: Automation; Cell Hypoxia; Fluorine Radioisotopes; Humans; Neoplasms; Nitroimidazoles

2011
Accessing radiation response using hypoxia PET imaging and oxygen sensitive electrodes: a preclinical study.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2011, Volume: 99, Issue:3

    Topics: Animals; Cell Hypoxia; Disease Models, Animal; Electrodes; Female; Fluorine Radioisotopes; Mammary Neoplasms, Experimental; Mice; Nitroimidazoles; Positron-Emission Tomography; Prognosis; Radiation Tolerance

2011
Investigation on tumor hypoxia in resectable primary prostate cancer as demonstrated by 18F-FAZA PET/CT utilizing multimodality fusion techniques.
    European journal of nuclear medicine and molecular imaging, 2011, Volume: 38, Issue:10

    Topics: Aged; Cell Hypoxia; Humans; Image Processing, Computer-Assisted; Male; Middle Aged; Multimodal Imaging; Nitroimidazoles; Positron-Emission Tomography; Prostatic Neoplasms; Sensitivity and Specificity; Tomography, X-Ray Computed

2011
Significant impact of different oxygen breathing conditions on noninvasive in vivo tumor-hypoxia imaging using [¹⁸F]-fluoro-azomycinarabino-furanoside ([¹⁸F]FAZA).
    Radiation oncology (London, England), 2011, Nov-25, Volume: 6

    Topics: Animals; Cell Hypoxia; Diagnostic Imaging; Fluorine Radioisotopes; Hypoxia; Image Processing, Computer-Assisted; Immunohistochemistry; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Neoplasms, Experimental; Nitroimidazoles; Oxygen; Positron-Emission Tomography; Radiopharmaceuticals; Respiration; Ribose

2011
Design, synthesis, and preliminary biological evaluation of 6-O-glucose-azomycin adducts for diagnosis and therapy of hypoxic tumors.
    Journal of medicinal chemistry, 2012, Jul-12, Volume: 55, Issue:13

    Topics: Cell Hypoxia; Cell Line, Tumor; Drug Design; Glucose Transport Proteins, Facilitative; Glucosides; Glycosides; Humans; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Misonidazole; Neoplasms; Nitroimidazoles; Radiation-Sensitizing Agents; Radionuclide Imaging; Radiopharmaceuticals; Transcriptional Activation

2012
PET hypoxia imaging with FAZA: reproducibility at baseline and during fractionated radiotherapy in tumour-bearing mice.
    European journal of nuclear medicine and molecular imaging, 2013, Volume: 40, Issue:2

    Topics: Animals; Body Weight; Cell Line, Tumor; Collagen; Dose Fractionation, Radiation; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Combinations; Female; Fluorine Radioisotopes; Humans; Hypoxia; Image Processing, Computer-Assisted; Laminin; Mice; Mice, Nude; Neoplasm Transplantation; Nitroimidazoles; Positron-Emission Tomography; Proteoglycans; Radiotherapy; Uterine Cervical Neoplasms

2013
Tumour hypoxia imaging with 18F-fluoroazomycinarabinofuranoside PET/CT in patients with locally advanced rectal cancer.
    Nuclear medicine communications, 2013, Volume: 34, Issue:2

    Topics: Aged; Biological Transport; Cell Hypoxia; Feasibility Studies; Female; Humans; Lymphatic Metastasis; Male; Middle Aged; Multimodal Imaging; Neoplasm Staging; Nitroimidazoles; Positron-Emission Tomography; Rectal Neoplasms; Tomography, X-Ray Computed; Tumor Burden; Urinary Bladder

2013
Comparison of 18F-fluoroazomycin-arabinofuranoside and 64Cu-diacetyl-bis(N4-methylthiosemicarbazone) in preclinical models of cancer.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2013, Volume: 54, Issue:7

    Topics: Animals; Cell Line, Tumor; Coordination Complexes; Copper Radioisotopes; Metabolic Clearance Rate; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms, Experimental; Nitroimidazoles; Organ Specificity; Organometallic Compounds; Positron-Emission Tomography; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity; Thiosemicarbazones; Tissue Distribution

2013
Pharmacokinetic analysis of [18F]FAZA in non-small cell lung cancer patients.
    European journal of nuclear medicine and molecular imaging, 2013, Volume: 40, Issue:10

    Topics: Aged; Carcinoma, Non-Small-Cell Lung; Female; Humans; Kinetics; Lung Neoplasms; Male; Middle Aged; Models, Biological; Nitroimidazoles; Positron-Emission Tomography; Radiopharmaceuticals

2013
PET imaging of tumor hypoxia using 18F-fluoroazomycin arabinoside in stage III-IV non-small cell lung cancer patients.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2013, Volume: 54, Issue:8

    Topics: Adult; Aged; Carcinoma, Non-Small-Cell Lung; Cell Hypoxia; Female; Fluorodeoxyglucose F18; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Nitroimidazoles; Positron-Emission Tomography; Tumor Burden

2013
Characterization of biological features of a rat F98 GBM model: a PET-MRI study with [18F]FAZA and [18F]FDG.
    Nuclear medicine and biology, 2013, Volume: 40, Issue:6

    Topics: Animals; Cell Differentiation; Cell Line, Tumor; Disease Models, Animal; Fluorodeoxyglucose F18; Glioblastoma; Humans; Magnetic Resonance Imaging; Male; Nitroimidazoles; Positron-Emission Tomography; Rats; Survival Analysis

2013
A prospective clinical study of ¹⁸F-FAZA PET-CT hypoxia imaging in head and neck squamous cell carcinoma before and during radiation therapy.
    European journal of nuclear medicine and molecular imaging, 2014, Volume: 41, Issue:8

    Topics: Aged; Carcinoma, Squamous Cell; Cell Hypoxia; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Nitroimidazoles; Oxygen; Positron-Emission Tomography; Prospective Studies; Radiopharmaceuticals

2014
Microwave-assisted radiosynthesis of the hypoxia marker 1-α-D-(5- deoxy-5-[18F]fluoroarabinofuranosyl)-2-nitroimidazole ([18F]FAZA).
    Current radiopharmaceuticals, 2014, Volume: 7, Issue:1

    Topics: Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Fluorine Radioisotopes; Hot Temperature; Humans; Hypoxia; Kinetics; Microwaves; Nitroimidazoles; Radiochemistry; Radiopharmaceuticals

2014
18FDG, [18F]FLT, [18F]FAZA, and 11C-methionine are suitable tracers for the diagnosis and in vivo follow-up of the efficacy of chemotherapy by miniPET in both multidrug resistant and sensitive human gynecologic tumor xenografts.
    BioMed research international, 2014, Volume: 2014

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Autoradiography; Carbon Radioisotopes; Cell Line, Tumor; Dideoxynucleosides; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Flow Cytometry; Fluorodeoxyglucose F18; Follow-Up Studies; Genital Neoplasms, Female; Humans; Methionine; Mice; Mice, SCID; Nitroimidazoles; Positron-Emission Tomography; Radiopharmaceuticals; Tumor Burden; Xenograft Model Antitumor Assays

2014
Parametric methods for quantification of 18F-FAZA kinetics in non-small cell lung cancer patients.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2014, Volume: 55, Issue:11

    Topics: Adult; Aged; Carcinoma, Non-Small-Cell Lung; Female; Humans; Kinetics; Lung Neoplasms; Male; Middle Aged; Nitroimidazoles; Positron-Emission Tomography; Radiopharmaceuticals; Regression Analysis; Reproducibility of Results; Time Factors; Tomography, X-Ray Computed; Treatment Outcome

2014
18F-FAZA PET imaging response tracks the reoxygenation of tumors in mice upon treatment with the mitochondrial complex I inhibitor BAY 87-2243.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2015, Jan-15, Volume: 21, Issue:2

    Topics: Animals; Antineoplastic Agents; Cell Hypoxia; Cell Line, Tumor; Dideoxynucleosides; Female; Fluorodeoxyglucose F18; Gene Expression Regulation, Neoplastic; Humans; Male; Mice, Nude; Nitroimidazoles; Oxadiazoles; Positron-Emission Tomography; Prostatic Neoplasms; Pyrazoles; Radiopharmaceuticals; Tumor Burden; Xenograft Model Antitumor Assays

2015
Potential role of hypoxia imaging using (18)F-FAZA PET to guide hypoxia-driven interventions (carbogen breathing or dose escalation) in radiation therapy.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2014, Volume: 113, Issue:2

    Topics: Animals; Carbon Dioxide; Cell Hypoxia; Diagnostic Imaging; Disease Models, Animal; Glioma; Male; Nitroimidazoles; Oximetry; Oxygen; Partial Pressure; Positron-Emission Tomography; Prognosis; Radiotherapy Planning, Computer-Assisted; Random Allocation; Rats; Rats, Inbred F344; Rhabdomyosarcoma

2014
Dynamics of tumor hypoxia assessed by 18F-FAZA PET/CT in head and neck and lung cancer patients during chemoradiation: possible implications for radiotherapy treatment planning strategies.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2014, Volume: 113, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cell Hypoxia; Chemoradiotherapy; Cohort Studies; Female; Head and Neck Neoplasms; Humans; Lung Neoplasms; Male; Middle Aged; Multimodal Imaging; Nitroimidazoles; Positron-Emission Tomography; Prospective Studies; Radiopharmaceuticals; Radiotherapy Planning, Computer-Assisted; Squamous Cell Carcinoma of Head and Neck; Tomography, X-Ray Computed

2014
A comparative study of the hypoxia PET tracers [¹⁸F]HX4, [¹⁸F]FAZA, and [¹⁸F]FMISO in a preclinical tumor model.
    International journal of radiation oncology, biology, physics, 2015, Feb-01, Volume: 91, Issue:2

    Topics: Animals; Cell Hypoxia; Cell Line, Tumor; Computer Simulation; Imidazoles; Misonidazole; Models, Biological; Nitroimidazoles; Oxygen; Positron-Emission Tomography; Radiopharmaceuticals; Rats; Reproducibility of Results; Rhabdomyosarcoma; Sensitivity and Specificity; Triazoles

2015
18F-FDG PET increases visibility of bone lesions in relapsed multiple myeloma: is this hypoxia-driven?
    Clinical nuclear medicine, 2015, Volume: 40, Issue:4

    Topics: Basic Helix-Loop-Helix Transcription Factors; Bone Marrow; Bone Neoplasms; Cell Hypoxia; Female; Fluorodeoxyglucose F18; Glucose Transporter Type 1; Glucose Transporter Type 3; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Middle Aged; Multiple Myeloma; Nitroimidazoles; Positron-Emission Tomography; Radiopharmaceuticals; Vascular Endothelial Growth Factor A

2015
Predictive value of (18)F-FAZA PET imaging for guiding the association of radiotherapy with nimorazole: a preclinical study.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2015, Volume: 114, Issue:2

    Topics: Animals; Cell Hypoxia; Chemoradiotherapy; Disease Models, Animal; Fluorine Radioisotopes; Glioma; Male; Nimorazole; Nitroimidazoles; Positron-Emission Tomography; Radiopharmaceuticals; Random Allocation; Rats; Rats, Inbred F344; Rhabdomyosarcoma

2015
A Comparative pO2 Probe and [18F]-Fluoro-Azomycinarabino-Furanoside ([18F]FAZA) PET Study Reveals Anesthesia-Induced Impairment of Oxygenation and Perfusion in Tumor and Muscle.
    PloS one, 2015, Volume: 10, Issue:4

    Topics: Anesthesia; Animals; Blood Pressure; Cell Line, Tumor; Female; Isoflurane; Ketamine; Mice, Inbred BALB C; Molecular Probes; Muscles; Neoplasms; Nitroimidazoles; Oxygen; Partial Pressure; Perfusion; Positron-Emission Tomography; Respiration; Systole; Xylazine

2015
Comparison of [18F]-FMISO, [18F]-FAZA and [18F]-HX4 for PET imaging of hypoxia--a simulation study.
    Acta oncologica (Stockholm, Sweden), 2015, Volume: 54, Issue:9

    Topics: Humans; Hypoxia; Imidazoles; Misonidazole; Models, Theoretical; Nitroimidazoles; Positron-Emission Tomography; Radiopharmaceuticals; Triazoles

2015
Assessment of hypoxic subvolumes in laryngeal cancer with (18)F-fluoroazomycinarabinoside ((18)F-FAZA)-PET/CT scanning and immunohistochemistry.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2015, Volume: 117, Issue:1

    Topics: Aged; Aged, 80 and over; Biomarkers; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Hypoxia; Laryngeal Neoplasms; Laryngectomy; Male; Middle Aged; Multimodal Imaging; Neoplasm Recurrence, Local; Nitroimidazoles; Pilot Projects; Positron-Emission Tomography; Prospective Studies; Radiopharmaceuticals; Squamous Cell Carcinoma of Head and Neck; Tomography, X-Ray Computed

2015
Quantitative and qualitative analysis of [(18)F]FDG and [(18)F]FAZA positron emission tomography of head and neck cancers and associations with HPV status and treatment outcome.
    European journal of nuclear medicine and molecular imaging, 2016, Volume: 43, Issue:4

    Topics: Adult; Aged; Data Interpretation, Statistical; Female; Fluorodeoxyglucose F18; Head and Neck Neoplasms; Humans; Male; Middle Aged; Nitroimidazoles; Papillomavirus Infections; Positron-Emission Tomography; Radiopharmaceuticals

2016
Multiparametric Analysis of the Relationship Between Tumor Hypoxia and Perfusion with ¹⁸F-Fluoroazomycin Arabinoside and ¹⁵O-H₂O PET.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2016, Volume: 57, Issue:4

    Topics: Aged; Carcinoma, Non-Small-Cell Lung; Cluster Analysis; Female; Humans; Hypoxia; Lung Neoplasms; Male; Middle Aged; Neoplasms; Nitroimidazoles; Oxygen Radioisotopes; Positron-Emission Tomography; Radiopharmaceuticals; Regional Blood Flow; Water

2016
Prognostic significance of hypoxic PET using (18)F-FAZA and (62)Cu-ATSM in non-small-cell lung cancer.
    Lung cancer (Amsterdam, Netherlands), 2016, Volume: 91

    Topics: Aged; Aged, 80 and over; Carcinoma, Non-Small-Cell Lung; Cell Hypoxia; Coordination Complexes; Drug Resistance, Neoplasm; Female; Fluorodeoxyglucose F18; Humans; Lung Neoplasms; Male; Middle Aged; Nitroimidazoles; Organometallic Compounds; Positron-Emission Tomography; Prognosis; Radiopharmaceuticals; Retrospective Studies; Survival Analysis; Thiosemicarbazones

2016
Measurement of Tumor Hypoxia in Patients with Advanced Pancreatic Cancer Based on 18F-Fluoroazomyin Arabinoside Uptake.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2016, Volume: 57, Issue:3

    Topics: Aged; Aged, 80 and over; Algorithms; Female; Humans; Hypoxia; Male; Middle Aged; Models, Biological; Neoplasm Metastasis; Nitroimidazoles; Pancreatic Neoplasms; Positron-Emission Tomography; Radiopharmaceuticals; Regional Blood Flow

2016
β -[
    Current radiopharmaceuticals, 2017, Volume: 10, Issue:2

    Topics: Animals; Cell Line, Tumor; Disease Models, Animal; Fluorine Radioisotopes; Male; Mice; Mice, Nude; Neoplasms; Nitroimidazoles; Positron-Emission Tomography; Radiochemistry; Radiopharmaceuticals; Tissue Distribution; Tumor Hypoxia

2017
Evolution of [
    Acta oncologica (Stockholm, Sweden), 2017, Volume: 56, Issue:4

    Topics: Aged; Female; Fluorodeoxyglucose F18; Humans; Image Interpretation, Computer-Assisted; Lung Neoplasms; Male; Middle Aged; Nitroimidazoles; Positron Emission Tomography Computed Tomography; Radiopharmaceuticals; Radiotherapy; Radiotherapy Dosage

2017
Concomitant Lung Cancer and Gastrointestinal Stromal Tumor: First Report of Hypoxia Imaging With 18F-FAZA PET/CT.
    Clinical nuclear medicine, 2017, Volume: 42, Issue:7

    Topics: Aged; Gastrointestinal Stromal Tumors; Humans; Lung Neoplasms; Male; Nitroimidazoles; Positron Emission Tomography Computed Tomography; Tumor Hypoxia

2017
Correlation analysis of [
    Acta oncologica (Stockholm, Sweden), 2017, Volume: 56, Issue:9

    Topics: Adenocarcinoma; Aged; Carcinoma, Squamous Cell; Female; Fluorodeoxyglucose F18; Humans; Lung Neoplasms; Male; Middle Aged; Nitroimidazoles; Positron Emission Tomography Computed Tomography; Prognosis; Radiopharmaceuticals; Radiotherapy Dosage; Radiotherapy Planning, Computer-Assisted; Small Cell Lung Carcinoma

2017
18F-FAZA PET/CT Hypoxia Imaging of High-Grade Glioma Before and After Radiotherapy.
    Clinical nuclear medicine, 2017, Volume: 42, Issue:12

    Topics: Clinical Trials as Topic; Glioma; Humans; Male; Middle Aged; Neoplasm Grading; Nitroimidazoles; Positron Emission Tomography Computed Tomography; Radiotherapy Planning, Computer-Assisted; Tumor Hypoxia

2017
18F-FAZA PET/CT in the Preoperative Evaluation of NSCLC: Comparison with 18F-FDG and Immunohistochemistry.
    Current radiopharmaceuticals, 2018, Volume: 11, Issue:1

    Topics: Aged; Aged, 80 and over; Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; Female; Fluorodeoxyglucose F18; Humans; Immunohistochemistry; Lung Neoplasms; Male; Middle Aged; Nitroimidazoles; Positron Emission Tomography Computed Tomography; Preoperative Care; Prospective Studies; Radiopharmaceuticals

2018
Hypoxia imaging with
    Radiation oncology (London, England), 2018, Mar-07, Volume: 13, Issue:1

    Topics: Adenocarcinoma; Animals; Cell Hypoxia; Cell Line, Tumor; Esophageal Neoplasms; Humans; Mice; Mice, Nude; Nimorazole; Nitroimidazoles; Positron Emission Tomography Computed Tomography; Radiation Tolerance; Radiopharmaceuticals; Xenograft Model Antitumor Assays

2018
Positron Emission Tomography (PET) and Pharmacokinetics: Classical Blood Sampling Versus Image-Derived Analysis of [18F]FAZA and [18F]FDG in a Murine Tumor Bearing Model.
    Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques, 2018, Volume: 21, Issue:1s

    Topics: Animals; Breast Neoplasms; Disaccharides; Disease Models, Animal; Female; Kinetics; Mice; Mice, Inbred BALB C; Nitroimidazoles; Positron-Emission Tomography; Tissue Distribution

2018
Synthesis of [
    Current radiopharmaceuticals, 2019, Volume: 12, Issue:1

    Topics: Fluorine Radioisotopes; Nitroimidazoles; Positron-Emission Tomography; Radiochemistry; Radiopharmaceuticals; Tumor Hypoxia

2019
Technical feasibility of [
    Radiation oncology (London, England), 2019, May-30, Volume: 14, Issue:1

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Disease Models, Animal; Feasibility Studies; Female; Glioblastoma; Nitroimidazoles; Positron-Emission Tomography; Radiopharmaceuticals; Radiotherapy Dosage; Radiotherapy, Image-Guided; Rats, Inbred F344; Treatment Outcome; Tumor Burden; Tyrosine

2019
Longitudinal PET Imaging to Monitor Treatment Efficacy by Liposomal Irinotecan in Orthotopic Patient-Derived Pancreatic Tumor Models of High and Low Hypoxia.
    Molecular imaging and biology, 2020, Volume: 22, Issue:3

    Topics: Animals; Cell Hypoxia; Female; Fluorine Radioisotopes; Irinotecan; Liposomes; Longitudinal Studies; Mice; Mice, Inbred NOD; Mice, SCID; Nitroimidazoles; Pancreatic Neoplasms; Positron-Emission Tomography; Radiopharmaceuticals; Topoisomerase I Inhibitors; Treatment Outcome; Xenograft Model Antitumor Assays

2020
Imaging of Hypoxic Tumor: Correlation between Diffusion-weighted MR Imaging and
    Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine, 2020, Aug-03, Volume: 19, Issue:3

    Topics: Cell Hypoxia; Diffusion Magnetic Resonance Imaging; Head and Neck Neoplasms; Humans; Nitroimidazoles; Positron-Emission Tomography; Radiopharmaceuticals

2020
Pharmacokinetic Analysis of [18F]FAZA Dynamic PET Imaging Acquisitions for Highlighting Sacrum Tumor Profiles.
    Clinical nuclear medicine, 2020, Volume: 45, Issue:1

    Topics: Clinical Trials as Topic; Female; Humans; Image Processing, Computer-Assisted; Male; Nitroimidazoles; Positron Emission Tomography Computed Tomography; Sacrum; Spinal Neoplasms

2020
Hypoxia and Amino Acid Imaging of High-Grade Glioma: 18F-FAZA PET/CT and 11C-Methionine PET/MRI.
    Clinical nuclear medicine, 2020, Volume: 45, Issue:6

    Topics: Adult; Amino Acids; Female; Glioma; Humans; Magnetic Resonance Imaging; Male; Methionine; Middle Aged; Neoplasm Grading; Nitroimidazoles; Positron Emission Tomography Computed Tomography; Tumor Hypoxia

2020
The role of 18F-FAZA PET/CT in detecting lymph node metastases in renal cell carcinoma patients: a prospective pilot trial.
    European journal of nuclear medicine and molecular imaging, 2021, Volume: 48, Issue:2

    Topics: Carcinoma, Renal Cell; Humans; Kidney Neoplasms; Lymph Nodes; Lymphatic Metastasis; Nitroimidazoles; Pilot Projects; Positron Emission Tomography Computed Tomography; Positron-Emission Tomography; Prospective Studies; Radiopharmaceuticals

2021
18F-FAZA PET/CT in pretreatment assessment of hypoxic status in high-grade glioma: correlation with hypoxia immunohistochemical biomarkers.
    Nuclear medicine communications, 2021, Jul-01, Volume: 42, Issue:7

    Topics: Adult; Humans; Male; Middle Aged; Nitroimidazoles; Positron Emission Tomography Computed Tomography; Positron-Emission Tomography

2021