azinomycin-b has been researched along with aminoacetone* in 1 studies
1 other study(ies) available for azinomycin-b and aminoacetone
Article | Year |
---|---|
Aminoacetone as the penultimate precursor to the antitumor agent azinomycin A.
Experiments reveal that the metabolic precursor aminoacetone is a key intermediate in the production of the antitumor agent azinomycin A relative to the structurally and functionally related agent, azinomycin B. Azinomycin A and B arise through bifurcation of the biosynthetic pathway and competition between metabolic substrates. The availability of the biosynthetic precursors in vivo, aminoacetone for azinomycin A and threonine for azinomycin B, controls the overall ratio of azinomycin A to B produced. Topics: Acetone; Antineoplastic Agents; Azabicyclo Compounds; Dipeptides; Glycopeptides; Intercellular Signaling Peptides and Proteins; Molecular Structure; Naphthalenes; Peptides | 2009 |