azides has been researched along with verapamil in 72 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 13 (18.06) | 18.7374 |
1990's | 50 (69.44) | 18.2507 |
2000's | 8 (11.11) | 29.6817 |
2010's | 1 (1.39) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Zernig, G | 1 |
Daniel, JC; Lecerf, JM; Levy, SB; Slapak, CA | 1 |
Naito, M; Tsuruo, T | 1 |
Charuk, JH; Reithmeier, RA | 1 |
Naito, M; Oh-hara, T; Sugawara, I; Tatsuta, T; Tsuruo, T | 1 |
Bruggemann, EP; Currier, SJ; Gottesman, MM; Pastan, I | 1 |
Anstett, M; Atassi, G; Bizzari, JP; Genton, A; Léonce, S; Pérez, V; Pierré, A | 1 |
deLeon, C; McGuire, WL; Speeg, KV | 1 |
Gottesman, MM; Horio, M; Lovelace, E; Pastan, I | 1 |
Suzuki, H; Tatsuta, T; Tomida, A | 1 |
Fukazawa, N; Sato, W; Suzuki, T; Tsuruo, T; Yusa, K | 1 |
Maeda, H; Miyamoto, Y | 1 |
Beck, WT; Qian, XD | 1 |
Akiyama, S; Douzono, H; Ikeda, S; Nagata, Y; Sugita, M; Sumizawa, T; Yoshimura, A | 1 |
Gindin, E; Greenberger, LM; Horwitz, SB; Yang, CP | 1 |
Arnold, ST; Felsted, RL; Politi, PM; Sinha, BK | 1 |
Bindslev, N; Demant, EJ; Friche, E; Jensen, PB; Sehested, M; Skovsgaard, T | 1 |
Demant, EJ; Friche, E; Jensen, PB; Nissen, NN; Sehested, M | 1 |
Catterall, WA; Glossmann, H; Striessnig, J | 1 |
Kvetny, J; Matzen, LE | 1 |
Cole, WC; Dhalla, NS; Kolar, F; Ostadal, B | 1 |
Ferry, DR; Glossmann, H; Goll, A; Schober, M; Striessnig, J | 1 |
Heisler, S | 1 |
Glossmann, H; Grabner, M; Knaus, HG; Lietz, H; Moosburger, K; Seitz, W; Striessnig, J | 1 |
Hofmann, F; Nastainczyk, W; Sieber, M; Wernet, W; Zubor, V | 1 |
Hofmann, F; Landgraf, W; Sieber, M; Wernet, W | 1 |
Glossmann, H; Hymel, L; Schindler, H; Striessnig, J | 1 |
Flockerzi, V | 1 |
Hudecová, S; Krizanová, O; Orlický, J; Zachar, J | 1 |
Arceci, RJ; DePinho, SG; Greenberger, LM; Horwitz, SB; Yang, CP | 1 |
Safa, AR; Spearman, T; Van Dyke, K; Ye, ZG | 1 |
Glossmann, H; Knaus, HG; Striessnig, J | 1 |
Beck, WT; Cirtain, MC; Felsted, RL; Glover, CJ; Safa, AR | 1 |
McMurtry, IF; Rounds, S | 1 |
Boiocchi, M; Cappelletto, B; Corona, G; Gigante, M; Raschack, M; Simone, F; Toffoli, G | 1 |
Bennis, S; Ichas, F; Robert, J | 1 |
Eliason, JF; Ishikawa, T; Ramuz, H; Tsuruo, T; Yamamoto, T; Yoshikubo, T | 1 |
Maare, C; Nielsen, D; Skovsgaard, T | 1 |
Bates, SE; Dickstein, B; Fojo, AT; Lee, JS; Spolyar, M | 1 |
Ashbourne, KJ; DiDiodato, G; Sharom, FJ; Yu, X | 1 |
Lahmy, S; Salmon, JM; Viallet, P | 1 |
Senior, AE; Urbatsch, IL | 1 |
Koseki, Y; Lothstein, L; Sweatman, TW | 1 |
Belehradek, J; Garrigos, M; Mir, LM; Orlowski, S | 1 |
Georges, E; Ling, V; Liu, Z; Zordan-Nudo, T | 1 |
Kang, Y; Perry, RR | 1 |
Gajdzik, L; Graf, J; Stapf, V; Thalhammer, T | 1 |
Abraham, I; Sampson, KE; Wolf, CL | 1 |
Itagaki, K; Kalasz, H; Kuniyasu, A; Mershon, J; Naito, K; Nakayama, H; Schwartz, A; Vaghy, PL; Watanabe, T; Yabana, H | 1 |
Burrows, GG; Glossmann, H; Hanner, M; Moebius, FF; Schmid, E; Striessnig, J | 1 |
Galkowska, H; Olszewski, WL | 1 |
Bamberger, U; Georges, E; Heckel, A; Lheureux, F; Liu, Z; Pouliot, JF | 1 |
Boer, R; Gekeler, V; Grunicke, H; Hofmann, J; Ise, W; Klemm, K; Sanders, KH; Schächtele, C; Schubert, C; Uberall, F; Utz, I | 1 |
Fujita, T; Fukuzumi, M; Muranishi, S; Nishimaki, A; Yamada, H; Yamamoto, A | 1 |
Chapey, C; Hu, YP; Robert, J | 1 |
Chen, G; Dumontet, C; Durán, GE; Jaffrézou, JP; Lacayo, NJ; Sikic, BI; Steger, KA | 1 |
Abu Khoudoud, OR; Bikhazi, AB; Bitar, KM; el-Kasti, MM; Ibrahim, MZ; Kreydiyyeh, SI; Saleh, RS | 1 |
Bhagat, S; Sankaran, B; Senior, AE | 1 |
Béliveau, R; Jetté, L; Murphy, GF | 1 |
Beck, WT; Dantzig, AH; Hsaio, SC; Pearce, HL; Shepard, RL; Winter, MA | 1 |
Airan, LE; Ambudkar, SV; Germann, UA; Gottesman, MM; Hrycyna, CA; Pastan, I | 1 |
Dey, S; Gottesman, MM; Hafkemeyer, P; Pastan, I | 1 |
Cheng, PW; Germann, UA; Gottesman, MM; Hrycyna, CA; Pastan, I; Ramachandra, M | 1 |
Chen, KG; Cohen, D; Durán, GE; Lacayo, NJ; Sikic, BI | 1 |
Fujita, R; Ishikawa, M; Sasaki, K; Takayanagi, M; Takayanagi, Y | 1 |
Melera, PW; Song, J | 2 |
Muharemagić, A; Senior, AE; Tombline, G; White, LB | 1 |
Chattopadhyay, A; Dey, S; Fong, WF; Shen, XL; Wan, CK; Zhu, GY | 1 |
Ambudkar, SV; Barnett, D; Bates, SE; Finley, EM; Fojo, T; Oldham, RK; Robey, RW; Shukla, S | 1 |
Cole, SP; Conseil, G; Deeley, RG; Lau, AY; Rothnie, A | 1 |
Abel, B; Ambudkar, SV; Durell, SR; Jacobson, KA; Murakami, M; Tosh, DK; Vahedi, S | 1 |
1 trial(s) available for azides and verapamil
Article | Year |
---|---|
Inhibition of P-glycoprotein (ABCB1)- and multidrug resistance-associated protein 1 (ABCC1)-mediated transport by the orally administered inhibitor, CBT-1((R)).
Topics: Adenosine Triphosphatases; Alkaloids; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Biological Factors; Biological Transport; Cell Line; Cell Line, Tumor; Cyclosporins; Depsipeptides; Fluorescent Dyes; Fluorouracil; Humans; Insecta; Multidrug Resistance-Associated Proteins; Neoplasms; Paclitaxel; Prazosin; Quinolines; Rhodamine 123; Verapamil; Vinblastine | 2008 |
71 other study(ies) available for azides and verapamil
Article | Year |
---|---|
Photoaffinity labeling of the partially purified mitochondrial phenylalkylamine calcium antagonist receptor.
Topics: Affinity Labels; Azides; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Electrophoresis, Polyacrylamide Gel; Mitochondria; Verapamil | 1992 |
Energy-dependent accumulation of daunorubicin into subcellular compartments of human leukemia cells and cytoplasts.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Cell Compartmentation; Chloroquine; Daunorubicin; Deoxyglucose; Dinitrophenols; Drug Interactions; Drug Resistance; Energy Metabolism; Ethylmaleimide; Humans; Leukemia; Membrane Glycoproteins; Methylamines; Microscopy, Fluorescence; Monensin; Ouabain; Sodium Azide; Tumor Cells, Cultured; Vanadates; Verapamil | 1992 |
Functionally active homodimer of P-glycoprotein in multidrug-resistant tumor cells.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Dihydropyridines; Doxorubicin; Drug Resistance; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Macromolecular Substances; Membrane Glycoproteins; Mitolactol; Mitomycins; Precipitin Tests; Succinimides; Tumor Cells, Cultured; Verapamil; Vincristine | 1992 |
Interaction of P-glycoprotein with a hydrophobic component of rat urine.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; CHO Cells; Cricetinae; Dihydropyridines; Drug Resistance; Female; Kinetics; Male; Membrane Glycoproteins; Rats; Tissue Extracts; Urine; Verapamil; Vinblastine | 1992 |
Functional involvement of P-glycoprotein in blood-brain barrier.
Topics: Alkaline Phosphatase; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Blood-Brain Barrier; Brain; Capillaries; Cells, Cultured; Drug Interactions; Endothelium, Vascular; gamma-Glutamyltransferase; Humans; Membrane Glycoproteins; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Microscopy, Immunoelectron; Prazosin; Tumor Cells, Cultured; Verapamil; Vincristine | 1992 |
Characterization of the azidopine and vinblastine binding site of P-glycoprotein.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Binding Sites; Cell Line; Cell Membrane; Colchicine; Cyanogen Bromide; Dihydropyridines; Drug Resistance; Humans; KB Cells; Kinetics; Membrane Glycoproteins; Molecular Weight; Peptide Fragments; Transfection; Trypsin; Verapamil; Vinblastine; Vincristine | 1992 |
Effects of a new triazinoaminopiperidine derivative on adriamycin accumulation and retention in cells displaying P-glycoprotein-mediated multidrug resistance.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Carcinoma, Squamous Cell; Cell Cycle; Cell Membrane; Cells, Cultured; Colonic Neoplasms; Cricetinae; Cricetulus; Dihydropyridines; Doxorubicin; Drug Resistance; Flow Cytometry; Fluorescence; Humans; Kinetics; Leukemia P388; Leukemia, Myeloid, Acute; Lung; Membrane Glycoproteins; Mice; Piperidines; Sensitivity and Specificity; Triazines; Tritium; Tumor Cells, Cultured; Verapamil | 1992 |
Uptake of the noncytotoxic transport probe procainamide in the Chinese hamster ovary model of multidrug resistance.
Topics: Animals; Azides; Calcium Channel Blockers; CHO Cells; Cimetidine; Cricetinae; Dose-Response Relationship, Drug; Drug Resistance; Procainamide; Solubility; Temperature; Tetraethylammonium Compounds; Verapamil | 1992 |
Agents which reverse multidrug-resistance are inhibitors of [3H]vinblastine transport by isolated vesicles.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Binding, Competitive; Biological Transport, Active; Carcinoma, Squamous Cell; Cell Membrane; Dihydropyridines; Drug Resistance; Humans; Kinetics; Leucine; Membrane Glycoproteins; Phenothiazines; Quinidine; Trifluoperazine; Tumor Cells, Cultured; Verapamil; Vinblastine | 1991 |
Novel mechanism of N-solanesyl-N,N'-bis(3,4-dimethoxybenzyl)ethylenediamine in potentiation of antitumor drug action on multidrug-resistant and sensitive Chinese hamster cells.
Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Cell Membrane; Cricetinae; Cricetulus; Daunorubicin; Dihydropyridines; Doxorubicin; Drug Resistance; Drug Synergism; Ethylenediamines; Membrane Glycoproteins; Terpenes; Verapamil; Vinblastine | 1991 |
Circumvention of multidrug resistance by a newly synthesized quinoline derivative, MS-073.
Topics: Affinity Labels; Animals; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Dihydropyridines; Drug Administration Schedule; Drug Resistance; Drug Screening Assays, Antitumor; Drug Synergism; Female; Leukemia P388; Membrane Glycoproteins; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Piperazines; Quinolines; Tumor Cells, Cultured; Verapamil; Vincristine | 1991 |
Enhancement by verapamil of neocarzinostatin action on multidrug-resistant Chinese hamster ovary cells: possible release of nonprotein chromophore in cells.
Topics: Animals; Antioxidants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Cell Division; Cell Line; Cell Membrane; Cell Survival; Cells, Cultured; Cricetinae; Cricetulus; Dihydropyridines; Drug Resistance; Drug Synergism; Female; Kinetics; Membrane Glycoproteins; Ovary; Verapamil; Zinostatin | 1991 |
Binding of an optically pure photoaffinity analogue of verapamil, LU-49888, to P-glycoprotein from multidrug-resistant human leukemic cell lines.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Drug Resistance; Humans; Leukemia; Membrane Glycoproteins; Neoplasm Proteins; Tumor Cells, Cultured; Verapamil | 1990 |
Aspergillus species strain M39 produces two naphtho-gamma-pyrones that reverse drug resistance in human KB cells.
Topics: Aspergillus; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Chemical Phenomena; Chemistry; Dihydropyridines; Doxorubicin; Drug Resistance; Humans; Membrane Glycoproteins; Naphthols; Pyrans; Pyrones; Verapamil; Vinblastine | 1990 |
Photoaffinity probes for the alpha 1-adrenergic receptor and the calcium channel bind to a common domain in P-glycoprotein.
Topics: Affinity Labels; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Binding Sites; Binding, Competitive; Calcium Channels; Cell Line; Cell Membrane; Chymotrypsin; Dihydropyridines; Drug Resistance; Macrophages; Membrane Glycoproteins; Mice; Peptide Mapping; Prazosin; Receptors, Adrenergic, alpha; Sequence Homology, Nucleic Acid; Verapamil | 1990 |
P-glycoprotein-independent mechanism of resistance to VP-16 in multidrug-resistant tumor cell lines: pharmacokinetic and photoaffinity labeling studies.
Topics: Affinity Labels; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Binding, Competitive; Breast Neoplasms; Cricetinae; Cricetulus; Dactinomycin; Doxorubicin; Drug Resistance; Etoposide; Humans; Membrane Glycoproteins; Neoplasm Proteins; Tumor Cells, Cultured; Verapamil; Vinblastine; Vindesine | 1990 |
Transport of the multidrug resistance modulators verapamil and azidopine in wild type and daunorubicin resistant Ehrlich ascites tumour cells.
Topics: Affinity Labels; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Carcinoma, Ehrlich Tumor; Cells, Cultured; Daunorubicin; Dihydropyridines; Dose-Response Relationship, Drug; Drug Resistance; Humans; In Vitro Techniques; Membrane Glycoproteins; Verapamil; Vincristine | 1990 |
The solvents cremophor EL and Tween 80 modulate daunorubicin resistance in the multidrug resistant Ehrlich ascites tumor.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Carcinoma, Ehrlich Tumor; Cyclosporins; Daunorubicin; Dihydropyridines; Drug Resistance; Drug Synergism; Drug Therapy, Combination; Glycerol; Humans; Intracellular Membranes; Membrane Glycoproteins; Polysorbates; Tritium; Tumor Cells, Cultured; Verapamil | 1990 |
Identification of a phenylalkylamine binding region within the alpha 1 subunit of skeletal muscle Ca2+ channels.
Topics: Affinity Labels; Amino Acid Sequence; Animals; Antibodies; Antigen-Antibody Complex; Azides; Binding Sites; Calcium Channels; Electrophoresis, Polyacrylamide Gel; Macromolecular Substances; Molecular Sequence Data; Molecular Weight; Muscles; Peptide Fragments; Rabbits; Trypsin; Verapamil | 1990 |
Effect of selective blockade of oxygen consumption, glucose transport, and Ca2+ influx on thyroxine action in human mononuclear cells.
Topics: Adult; Alprenolol; Azides; Biological Transport; Calcium; Cytochalasin B; Glucose; Humans; Middle Aged; Mitochondria; Monocytes; Oxygen Consumption; Sodium Azide; Thyroxine; Verapamil | 1990 |
Transient inotropic effects of low extracellular sodium in perfused rat heart.
Topics: Amiloride; Animals; Azides; Calcium; Extracellular Space; In Vitro Techniques; Male; Myocardial Contraction; Myocardium; Osmolar Concentration; Ouabain; Rats; Rats, Inbred Strains; Ryanodine; Sodium; Sodium Azide; Time Factors; Verapamil | 1990 |
Calcium channels: basic properties as revealed by radioligand binding studies.
Topics: Affinity Labels; Animals; Azides; Binding Sites; Binding, Competitive; Brain; Calcium; Calcium Channel Blockers; Dihydropyridines; Guinea Pigs; Iodobenzenes; Ion Channels; Molecular Weight; Muscles; Neurilemma; Photochemistry; Pyridines; Sarcolemma; Verapamil | 1985 |
BAY-K-8644-stimulated cyclic GMP synthesis in mouse pituitary tumor cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenocorticotropic Hormone; Animals; Azides; Cells, Cultured; Cyclic GMP; Dose-Response Relationship, Drug; Isoproterenol; Mice; Nifedipine; Nitroprusside; Pituitary Neoplasms; Sodium Azide; Stimulation, Chemical; Verapamil | 1986 |
Photoaffinity labelling of the phenylalkylamine receptor of the skeletal muscle transverse-tubule calcium channel.
Topics: Affinity Labels; Animals; Azides; Calcium Channels; Guinea Pigs; Ion Channels; Kinetics; Molecular Weight; Muscles; Receptors, Nicotinic; Verapamil | 1987 |
The 165-kDa peptide of the purified skeletal muscle dihydropyridine receptor contains the known regulatory sites of the calcium channel.
Topics: Affinity Labels; Animals; Azides; Calcium; Calcium Channels; Dihydropyridines; Ion Channels; Isradipine; Kinetics; Molecular Weight; Muscles; Oxadiazoles; Pyridines; Rabbits; Receptors, Nicotinic; Verapamil | 1987 |
Rabbit skeletal muscle microsomes contain two distinct phenylalkylamine-binding sites.
Topics: Affinity Labels; Amines; Animals; Azides; Binding Sites; Centrifugation, Density Gradient; Ion Channels; Microsomes; Muscles; Photochemistry; Rabbits; Verapamil | 1988 |
Purification and reconstitution of calcium channel drug-receptor sites.
Topics: Affinity Labels; Animals; Azides; Calcium; Calcium Channels; Dihydropyridines; Guinea Pigs; Ion Channels; Muscles; Receptors, Drug; Receptors, Nicotinic; Verapamil | 1988 |
Molecular properties of voltage-activated calcium channels.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Affinity Labels; Animals; Azides; Calcium Channels; Cloning, Molecular; Dihydropyridines; DNA; Glycoproteins; Muscles; Phosphorylation; Protein Conformation; Protein Kinases; Receptors, Nicotinic; Verapamil | 1989 |
Is Ca2+ antagonists binding protein from cytosolic fraction the precursor of alpha 1-subunit of Ca2+ channel?
Topics: Affinity Labels; Animals; Antibodies; Azides; Binding, Competitive; Calcium Channel Blockers; Calcium Channels; Cytoplasm; Dihydropyridines; In Vitro Techniques; Isradipine; Muscles; Oxadiazoles; Protein Precursors; Rabbits; Radioligand Assay; Receptors, Nicotinic; Ultraviolet Rays; Verapamil | 1989 |
Progesterone interacts with P-glycoprotein in multidrug-resistant cells and in the endometrium of gravid uterus.
Topics: Affinity Labels; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Cell Line; Dihydropyridines; Drug Resistance; Endometrium; Estradiol; Female; Intracellular Membranes; Kinetics; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Microsomes; Pregnancy; Pregnancy, Animal; Progesterone; Protein Binding; Steroids; Verapamil; Vinblastine | 1989 |
3H-azidopine photoaffinity labeling of high molecular weight proteins in chloroquine resistant falciparum malaria.
Topics: Affinity Labels; Animals; Azides; Binding, Competitive; Chloroquine; Chlorpromazine; Dihydropyridines; Drug Resistance; Glycoproteins; Molecular Weight; Nicardipine; Photochemistry; Plasmodium falciparum; Proteins; Quinacrine; Reserpine; Trifluoperazine; Verapamil | 1989 |
Photoaffinity-labelling of the calcium-channel-associated 1,4-dihydropyridine and phenylalkylamine receptor in guinea-pig hippocampus. A 195 kDa polypeptide carries both drug receptors and has similarities to the alpha 1 subunit of the purified skeletal-m
Topics: Affinity Labels; Animals; Azides; Calcium Channel Blockers; Calcium Channels; Cell Membrane; Dihydropyridines; Guinea Pigs; Hippocampus; In Vitro Techniques; Kinetics; Muscles; Peptides; Radioimmunoassay; Receptors, Nicotinic; Tritium; Verapamil | 1988 |
Effects of indole alkaloids on multidrug resistance and labeling of P-glycoprotein by a photoaffinity analog of vinblastine.
Topics: Affinity Labels; Alkaloids; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Cell Survival; Chloroquine; Drug Interactions; Drug Resistance; Humans; Indoles; Leukemia; Membrane Glycoproteins; Photochemistry; Quinacrine; Quinine; Reserpine; Verapamil; Vinblastine; Vinca Alkaloids; Vindesine; Yohimbine | 1988 |
Inhibitors of oxidative ATP production cause transient vasoconstriction and block subsequent pressor responses in rat lungs.
Topics: Adenosine Triphosphate; Angiotensin II; Animals; Antimycin A; Azides; Blood Pressure; Calcium; Dinitrophenols; Hypoxia; Lung; Male; Perfusion; Potassium Cyanide; Pulmonary Circulation; Rats; Rotenone; Sodium Azide; Solvents; Vasoconstriction; Verapamil | 1981 |
Structure-activity relationship of verapamil analogs and reversal of multidrug resistance.
Topics: Animals; Antineoplastic Agents; Aorta; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Calcium; Dihydropyridines; Doxorubicin; Drug Design; Drug Resistance, Microbial; Drug Resistance, Multiple; Drug Synergism; Humans; Male; Rats; Rats, Sprague-Dawley; RNA, Messenger; Structure-Activity Relationship; Tumor Cells, Cultured; Tumor Stem Cell Assay; Verapamil | 1995 |
Differential effects of verapamil and quinine on the reversal of doxorubicin resistance in a human leukemia cell line.
Topics: Affinity Labels; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Dihydropyridines; Doxorubicin; Drug Resistance; Drug Screening Assays, Antitumor; Drug Synergism; Humans; Kinetics; Leukemia, Erythroblastic, Acute; Microscopy, Confocal; Microscopy, Fluorescence; Phenotype; Quinine; Subcellular Fractions; Tumor Cells, Cultured; Verapamil | 1995 |
Novel dithiane analogues of tiapamil with high activity to overcome multidrug resistance in vitro.
Topics: Animals; Aorta; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Dihydropyridines; Doxorubicin; Drug Resistance, Multiple; In Vitro Techniques; Propylamines; Rats; Stereoisomerism; Tiapamil Hydrochloride; Tumor Cells, Cultured; Verapamil; Vincristine | 1995 |
Influx of daunorubicin in multidrug resistant Ehrlich ascites tumour cells: correlation to expression of P-glycoprotein and efflux. Influence of verapamil.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Carcinoma, Ehrlich Tumor; Daunorubicin; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Female; Gene Expression Regulation; Glucose; Male; Mice; Mice, Inbred DBA; Sodium Azide; Tumor Cells, Cultured; Verapamil | 1995 |
Differential modulation of P-glycoprotein transport by protein kinase inhibition.
Topics: Affinity Labels; Alkaloids; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Biological Transport; Carrier Proteins; Cyclosporine; Dactinomycin; Dihydropyridines; Drug Resistance; Humans; Isoenzymes; Membrane Glycoproteins; Naphthalenes; Polycyclic Compounds; Protein Kinase C; Rhodamine 123; Rhodamines; Staurosporine; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Verapamil; Vinblastine; Vincristine | 1993 |
Interaction of the P-glycoprotein multidrug transporter with peptides and ionophores.
Topics: Adenosine Triphosphatases; Affinity Labels; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Biological Transport; Cell Membrane; CHO Cells; Cricetinae; Dihydropyridines; Enzyme Activation; Ionophores; Peptides; Photochemistry; Protein Binding; Verapamil | 1995 |
Is reduced accumulation of Hoechst 33342 in multidrug resistant cells related to P-glycoprotein activity?
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Benzimidazoles; Binding, Competitive; Cell Line; Cell Nucleus; Drug Resistance, Multiple; Flow Cytometry; Fluorescent Dyes; Humans; Mass Spectrometry; Osmolar Concentration; Sodium Azide; Time Factors; Verapamil; Vinblastine | 1995 |
Effects of lipids on ATPase activity of purified Chinese hamster P-glycoprotein.
Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Binding, Competitive; Brain Chemistry; Cattle; Cell Membrane; Colchicine; Cricetinae; Cricetulus; Daunorubicin; Dihydropyridines; Escherichia coli; Lipids; Liver; Proteolipids; Sheep; Verapamil; Vinblastine | 1995 |
P-glycoprotein overexpression in mouse cells does not correlate with resistance to N-benzyladriamycin-14-valerate (AD 198).
Topics: Affinity Labels; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Cells, Cultured; Dihydropyridines; DNA Topoisomerases, Type II; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance; Immunoblotting; Mice; Tumor Cells, Cultured; Verapamil | 1994 |
Absence of cooperativity for MgATP and verapamil effects on the ATPase activity of P-glycoprotein containing membrane vesicles.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Carrier Proteins; Cell Line; Cell Membrane; Cell Survival; Colchicine; Cricetinae; Cricetulus; Dactinomycin; Drug Interactions; Drug Resistance; Electrophoresis, Disc; Kinetics; Lung; Membrane Glycoproteins; Membrane Proteins; Ouabain; Sodium Azide; Verapamil; Vincristine | 1993 |
Effects of nonionic detergents on P-glycoprotein drug binding and reversal of multidrug resistance.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Carrier Proteins; Cells, Cultured; Cholic Acids; Detergents; Dihydropyridines; Drug Resistance; Humans; Membrane Glycoproteins; Octoxynol; Verapamil | 1993 |
Effect of alpha-interferon on P-glycoprotein expression and function and on verapamil modulation of doxorubicin resistance.
Topics: Affinity Labels; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Binding, Competitive; Carrier Proteins; Cell Line; Cricetinae; Dihydropyridines; Doxorubicin; Drug Resistance; Drug Synergism; Interferon-alpha; Membrane Glycoproteins; RNA, Messenger; Verapamil | 1994 |
Bile canalicular cationic dye secretion as a model for P-glycoprotein mediated transport.
Topics: Acridine Orange; Affinity Labels; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Bile Canaliculi; Blotting, Western; Carrier Proteins; Cell Membrane; Cyclosporine; Dihydropyridines; In Vitro Techniques; Liver; Male; Membrane Glycoproteins; Models, Biological; Perfusion; Precipitin Tests; Rats; Rats, Inbred Strains; Verapamil | 1994 |
Non-glucocorticoid steroid analogues (21-aminosteroids) sensitize multidrug resistant cells to vinblastine.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Cell Survival; Dihydropyridines; Drug Interactions; Drug Resistance; Humans; KB Cells; Membrane Glycoproteins; Pregnatrienes; Structure-Activity Relationship; Verapamil; Vinblastine | 1993 |
Azidobutyryl clentiazem, a new photoactivatable diltiazem analog, labels benzothiazepine binding sites in the alpha 1 subunit of the skeletal muscle calcium channel.
Topics: Affinity Labels; Animals; Azides; Benzodiazepines; Binding Sites; Binding, Competitive; Calcium Channel Blockers; Calcium Channels; Cattle; Diltiazem; Muscles; Precipitin Tests; Rabbits; Verapamil | 1993 |
Identification of a 27-kDa high affinity phenylalkylamine-binding polypeptide as the sigma 1 binding site by photoaffinity labeling and ligand-directed antibodies.
Topics: Affinity Labels; Amines; Animals; Azides; Binding Sites; Guinea Pigs; Immune Sera; In Vitro Techniques; Microsomes, Liver; Molecular Weight; Peptides; Photochemistry; Receptors, sigma; Verapamil | 1993 |
Skin dendritic cell-lymphocyte interactions in autologous system.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Azides; Cell Adhesion; Dendritic Cells; Deoxyribonucleases; Dogs; Edetic Acid; Endopeptidases; Epidermis; Heparin; Immunosuppressive Agents; Lidocaine; Lymph; Lymphedema; Lymphocytes; Neuraminidase; Sodium Azide; Tretinoin; Verapamil | 1993 |
BIBW22 BS, potent multidrug resistance-reversing agent, binds directly to P-glycoprotein and accumulates in drug-resistant cells.
Topics: Affinity Labels; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Binding Sites; Cell Line; Cell Survival; CHO Cells; Colchicine; Cricetinae; Dihydropyridines; Doxorubicin; Drug Resistance, Multiple; Humans; Kinetics; Lymphoma; Morpholines; Peptide Mapping; Protein Binding; Triamterene; Tumor Cells, Cultured; Verapamil; Vinblastine | 1996 |
Effects of the selective bisindolylmaleimide protein kinase C inhibitor GF 109203X on P-glycoprotein-mediated multidrug resistance.
Topics: 3T3 Cells; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Dihydropyridines; Drug Resistance, Multiple; Enzyme Inhibitors; Gene Expression; Humans; Indoles; Maleimides; Mice; Phosphorylation; Protein Kinase C; Verapamil | 1996 |
Calcein is excreted from the intestinal mucosal cell membrane by the active transport system.
Topics: Animals; Azides; Biological Transport, Active; Caco-2 Cells; Calcium Channel Blockers; Cell Membrane; Cell Membrane Permeability; Daunorubicin; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; In Vitro Techniques; Intestinal Mucosa; Jejunum; Probenecid; Rats; Renal Agents; Sodium Azide; Sodium Fluoride; Verapamil | 1997 |
Relationship between the inhibition of azidopine binding to P-glycoprotein by MDR modulators and their efficiency in restoring doxorubicin intracellular accumulation.
Topics: Affinity Labels; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Cyclosporine; Cyclosporins; Dihydropyridines; Doxorubicin; Drug Resistance, Multiple; Humans; Mice; Nicardipine; Piperidines; Triazines; Tumor Cells, Cultured; Verapamil | 1996 |
Multidrug-resistant human sarcoma cells with a mutant P-glycoprotein, altered phenotype, and resistance to cyclosporins.
Topics: Affinity Labels; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Blotting, Western; Cell Survival; Cyclosporins; Dihydropyridines; DNA Topoisomerases, Type II; Doxorubicin; Drug Resistance, Multiple; Humans; Neoplasm Proteins; Phenotype; Polymerase Chain Reaction; Prazosin; Rhodamine 123; Rhodamines; Sarcoma; Vault Ribonucleoprotein Particles; Verapamil | 1997 |
Binding and distribution of three prototype calcium channel blockers in perfused rat liver.
Topics: Animals; Azides; Calcium Channel Blockers; Calcium Channels; Carbon Radioisotopes; Dihydropyridines; Inulin; Isradipine; Liver; Models, Biological; Perfusion; Rats; Rats, Sprague-Dawley; Time Factors; Tritium; Urea; Verapamil | 1997 |
Inhibition of P-glycoprotein ATPase activity by beryllium fluoride.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Affinity Labels; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Beryllium; Binding, Competitive; Cations, Divalent; CHO Cells; Cricetinae; Enzyme Inhibitors; Enzyme Reactivators; Fluorides; Kinetics; Phosphates; Sodium Fluoride; Ultraviolet Rays; Verapamil | 1997 |
Drug binding to P-glycoprotein is inhibited in normal tissues following SDZ-PSC 833 treatment.
Topics: Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Blotting, Western; Brain; Calcium Channel Blockers; Capillaries; Cyclosporine; Cyclosporins; Drug Interactions; Fluorescent Dyes; Injections, Subcutaneous; Iodine Radioisotopes; Kidney; Liver; Male; Microvilli; Photoaffinity Labels; Prazosin; Rats; Rats, Sprague-Dawley; Rhodamine 123; Rhodamines; Verapamil; Vinblastine | 1998 |
Effect of modulators on the ATPase activity and vanadate nucleotide trapping of human P-glycoprotein.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Binding Sites; Calcium Channel Blockers; Cell Membrane; Drug Interactions; Drug Resistance, Multiple; Humans; Hydrolysis; Leukemia, Lymphoid; Phosphorus Radioisotopes; Protein Conformation; Stimulation, Chemical; Tumor Cells, Cultured; Vanadates; Verapamil; Vinblastine; Yohimbine | 1998 |
Structural flexibility of the linker region of human P-glycoprotein permits ATP hydrolysis and drug transport.
Topics: 3T3 Cells; Adenosine Triphosphatases; Adenosine Triphosphate; Amino Acid Sequence; Animals; Antibodies, Monoclonal; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Base Sequence; Biological Transport; Cell Membrane; Drug Resistance, Multiple; Genetic Vectors; HeLa Cells; Humans; Hydrolysis; Iodine Radioisotopes; Mice; Molecular Sequence Data; Mutagenesis, Insertional; Osteosarcoma; Peptide Fragments; Prazosin; Protein Binding; Protein Conformation; Recombinant Proteins; Sequence Deletion; Tumor Cells, Cultured; Verapamil | 1998 |
A single amino acid residue contributes to distinct mechanisms of inhibition of the human multidrug transporter by stereoisomers of the dopamine receptor antagonist flupentixol.
Topics: Adenosine Triphosphate; Alanine; Amino Acid Substitution; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Biological Transport; Dopamine Antagonists; Flupenthixol; HeLa Cells; Humans; Hydrolysis; Iodine Radioisotopes; Mutagenesis, Site-Directed; Phenylalanine; Photoaffinity Labels; Prazosin; Receptors, Dopamine; Stereoisomerism; Substrate Specificity; Tumor Cells, Cultured; Verapamil | 1999 |
Both ATP sites of human P-glycoprotein are essential but not symmetric.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Amino Acid Motifs; Amino Acid Substitution; Antibodies, Monoclonal; Asparagine; Aspartic Acid; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Binding Sites; Biological Transport; Body Temperature; Cell Membrane; Consensus Sequence; Enzyme Activation; Freezing; HeLa Cells; Humans; Peptide Fragments; Phosphorus Radioisotopes; Photoaffinity Labels; Point Mutation; Prazosin; Protein Conformation; Recombinant Fusion Proteins; Vanadates; Verapamil | 1999 |
Loss of cyclosporin and azidopine binding are associated with altered ATPase activity by a mutant P-glycoprotein with deleted phe(335).
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Amino Acid Sequence; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Binding Sites; Calcium Channel Blockers; Cyclosporine; Dihydropyridines; Drug Interactions; Enzyme Activation; Humans; Molecular Sequence Data; Phenylalanine; Photoaffinity Labels; Tritium; Tumor Cells, Cultured; Vanadates; Verapamil | 2000 |
Enhancement of doxorubicin activity in multidrug-resistant cells by mefloquine.
Topics: Affinity Labels; Antibiotics, Antineoplastic; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Binding, Competitive; Calcium Channel Blockers; Coloring Agents; Dihydropyridines; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Humans; Mefloquine; Phenotype; Rhodamine 123; Tumor Cells, Cultured; Verapamil | 2000 |
Transmembrane domain (TM) 9 represents a novel site in P-glycoprotein that affects drug resistance and cooperates with TM6 to mediate [125I]iodoarylazidoprazosin labeling.
Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Binding, Competitive; Cells, Cultured; Cricetinae; Cyclosporine; Drug Interactions; Drug Resistance; Drug Resistance, Multiple; Iodine Radioisotopes; Membrane Proteins; Mutagenesis, Site-Directed; Prazosin; Protein Structure, Tertiary; Transfection; Verapamil | 2001 |
Further characterization of the sixth transmembrane domain of Pgp1 by site-directed mutagenesis.
Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Cell Line; Cricetinae; Hydrophobic and Hydrophilic Interactions; Membrane Proteins; Mutagenesis, Site-Directed; Photoaffinity Labels; Prazosin; Structure-Activity Relationship; Transfection; Verapamil | 2001 |
Involvement of the "occluded nucleotide conformation" of P-glycoprotein in the catalytic pathway.
Topics: 4-Chloro-7-nitrobenzofurazan; Adenosine Triphosphate; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Catalysis; Enzyme Inhibitors; Ethylmaleimide; Glutamic Acid; Kinetics; Mice; Mutation; Photoaffinity Labels; Protein Conformation; Verapamil | 2005 |
Gomisin A alters substrate interaction and reverses P-glycoprotein-mediated multidrug resistance in HepG2-DR cells.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Anticarcinogenic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Blotting, Western; Cell Line, Tumor; Cell Survival; Cyclooctanes; Dioxoles; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Humans; Hydrolysis; Lignans; Prazosin; Reverse Transcriptase Polymerase Chain Reaction; Rhodamine 123; RNA, Messenger; Vanadates; Verapamil; Vinblastine | 2006 |
Mechanistic differences between GSH transport by multidrug resistance protein 1 (MRP1/ABCC1) and GSH modulation of MRP1-mediated transport.
Topics: Adenosine Triphosphate; Apigenin; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Binding Sites; Binding, Competitive; Cell Line, Tumor; Estrone; Glutathione; Humans; Hydrolysis; Leukotriene C4; Phosphorus Radioisotopes; Protein Binding; Protein Transport; Signal Transduction; Verapamil; Vincristine | 2008 |
Evidence for the Interaction of A
Topics: Adenosine A3 Receptor Agonists; ATP Binding Cassette Transporter, Subfamily B; Azides; Binding Sites; HeLa Cells; Humans; Models, Molecular; Molecular Docking Simulation; Paclitaxel; Prazosin; Structure-Activity Relationship; Verapamil | 2019 |