azides has been researched along with triazoles in 455 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 37 (8.13) | 18.7374 |
| 1990's | 1 (0.22) | 18.2507 |
| 2000's | 67 (14.73) | 29.6817 |
| 2010's | 282 (61.98) | 24.3611 |
| 2020's | 68 (14.95) | 2.80 |
| Authors | Studies |
|---|---|
| Volfová, O; Vorísek, J | 1 |
| Cieśla, Z; Filutowicz, M; Kłopotowski, T | 1 |
| Lauritis, JA; Sherman, L; Swift, H; Vigil, EL | 1 |
| Chignard, M; Tranier, Y; Vargaftig, BB | 1 |
| Klebanoff, SJ | 1 |
| Gangolli, SD; Heading, CE; Lake, BG; Lloyd, AG; Minski, MJ; Phillips, JC | 1 |
| Bollag, JM; Henniger, NM | 1 |
| Fahimi, HD | 2 |
| Nir, I; Seligman, AM | 1 |
| Hopkins, J; Tudhope, GR | 1 |
| Hirai, KI | 1 |
| DeCarli, LM; Lieber, CS | 1 |
| Butt, VS; Halliwell, B | 1 |
| Creaven, PJ; Reese, WN; Roach, MK | 1 |
| Carter, EA; Isselbacher, KJ | 1 |
| Kalant, H; Khanna, JM; Lin, G | 1 |
| Reddy, J; Svoboda, D | 1 |
| Cornwell, DG; Geer, JC; Panganamala, RV; Sharma, HM; Sprecher, H | 1 |
| Feinstein, RN; Howard, JB; Jaroslow, BN | 1 |
| Nichol, AW | 1 |
| McRipley, RJ; Sbarra, AJ | 1 |
| Iyer, GY; Paniker, NV | 1 |
| Feinstein, RN | 1 |
| Breton-Gorius, J; Guichard, J | 1 |
| Hornyák, M; Schawartz, J; Süts, T | 1 |
| Blank, HU; Fox, JJ; Wempen, I | 1 |
| Kurzer, F; Wilkinson, M | 2 |
| Reed, PW | 1 |
| Müller, M; Rapoport, S | 1 |
| Braun, JT; Feinstein, RN; Howard, JB | 1 |
| Cook, JA; Ford, PC; Grisham, MB; Krishna, MC; Miles, AM; Nims, RW; Pacelli, R; Poore, CM; Teague, D; Wink, DA | 1 |
| Atack, JR; Bristow, L; Brown, N; Carling, RW; Castro, JL; Cook, G; Dawson, GR; Farrar, S; Ferris, P; Garrett, L; Howell, O; Macaulay, A; Marshall, G; McKernan, RM; Moore, KW; Myers, J; Ragan, CI; Reynolds, DS; Rosahl, TW; Street, LJ; Sur, C; Wafford, KA; Whiting, PJ | 1 |
| Hevers, W; Korpi, ER; Lüddens, H | 1 |
| Altinok, G; Demirdamar, R; Kelicen, P; Palaska, E; Sahin, G | 1 |
| Thomas, AW | 1 |
| Fokin, VV; Huang, SJ; Lee, LV; Mitchell, ML; Sharpless, KB; Wong, CH | 1 |
| JENEY, E; ZSOLNAI, T | 1 |
| HACKETT, DP; KLAPPER, MH | 1 |
| BALLONOFF, LB; FEINSTEIN, RN; SEAHOLM, JE | 1 |
| ZSOLANI, T | 1 |
| GALTON, VA; INGBAR, SH; VONDERHEYDE, S | 1 |
| Fokin, VV; Krasiński, A; Sharpless, KB | 1 |
| Fahrni, CJ; Zhou, Z | 1 |
| Feldman, AK; Fokin, VV; Fréchet, JM; Hawker, CJ; Nugent, AK; Pyun, J; Scheel, A; Sharpless, KB; Voit, B; Wu, P | 1 |
| Link, AJ; Tirrell, DA; Vink, MK | 1 |
| Colasson, B; Feldman, AK; Fokin, VV | 1 |
| Basu, A; Rossi, LL | 1 |
| Looper, RE; Pizzirani, D; Schreiber, SL | 1 |
| Hsung, RP; You, L; Zhang, X | 1 |
| Guan, Z; Oh, K | 1 |
| Chidsey, CE; Collman, JP; Decreau, RA; Devaraj, NK; Ebina, W | 1 |
| Bindu, L; Burke, TR; Choi, WJ; Fisher, RJ; Karki, RG; Nicklaus, MC; Shi, ZD; Worthy, KM | 1 |
| Dondoni, A; Marra, A | 1 |
| Cheng, Y; McCammon, JA; Senapati, S | 1 |
| Cheshev, P; Dondoni, A; Marra, A | 1 |
| Anguelov, T; Brans, L; Maes, V; Mindt, TL; Schibli, R; Schweinsberg, C; Struthers, H; Tourwé, D | 1 |
| Bongat, AF; Demchenko, AV | 1 |
| Beckmann, HS; Wittmann, V | 1 |
| Barral, K; Moorhouse, AD; Moses, JE | 1 |
| Angell, Y; Burgess, K | 1 |
| Bodnar, BS; Miller, MJ | 1 |
| Berro, C; Fan, Z; Li, W; Liu, X; Peng, L; Qu, F; Rauzy, E; Xia, Y | 1 |
| Baxendale, IR; Hayward, JJ; Lanners, S; Ley, SV; Smith, CD; Smith, SC | 1 |
| Moorhouse, AD; Moses, JE | 1 |
| Cornelissen, JJ; Debets, MF; Dirks, AT; Nolte, RJ; Rutjes, FP; van Berkel, SS; van Delft, FL | 1 |
| Billington, RA; Canonico, PL; Genazzani, AA; Pirali, T; Sorba, G; Tron, GC | 1 |
| Arndt, HD; Hu, TS; Tannert, R; Waldmann, H | 1 |
| Finn, MG; Gardinier, S; Lim, YH; Presolski, SI; Rodionov, VO | 1 |
| Díaz, DD; Finn, MG; Fokin, VV; Presolski, SI; Rodionov, VO | 1 |
| Dupradeau, FY; Fernandez, JM; Gouin, SG; Kovensky, J; Mellet, CO; Vanquelef, E | 1 |
| Ankamma, K; Kumaraswamy, G; Pitchaiah, A | 1 |
| Arora, BS; Ismail, T; Kumar, HM; Shafi, S; Singh, S | 1 |
| Fujino, T; Marine, G; Nakamura, E | 1 |
| da Silva, EN; De Castro, SL; De Simone, CA; de Souza, MC; Ferreira, VF; Menna-Barreto, RF; Pinto, AV; Pinto, Mdo C; Silva, RS; Teixeira, DV | 1 |
| Agrofoglio, LA; Andrei, G; Aucagne, V; Balzarini, J; Berteina-Raboin, S; Broggi, J; Deville-Bonne, D; Diez-Gonzalez, S; Joubert, N; Neyts, J; Nolan, S; Snoeck, R; Topalis, D | 1 |
| Kumar, R; Maulik, PR; Misra, AK | 1 |
| Chiappe, C; Dondoni, A; Marra, A; Melai, B; Vecchi, A | 1 |
| Chaturvedi, V; Gaikwad, A; Kumar, B; Singh, BK; Sinha, SK; Tripathi, RP; Yadav, AK | 1 |
| Ding, L; Hu, H; Lei, X; Zhang, A; Zhang, L | 1 |
| Chen, Y; Larock, RC; Shi, F; Waldo, JP | 1 |
| Donnelly, PS; White, JM; Williams, SJ; Zammit, SC; Zanatta, SD | 1 |
| Evans, RA; Finn, MG; Hong, V; Udit, AK | 1 |
| Ahlquist, M; Bae, I; Chang, S; Fokin, VV; Sharpless, KB; Yoo, EJ | 1 |
| Boren, BC; Fokin, VV; Jia, G; Lin, Z; Narayan, S; Rasmussen, LK; Zhang, L; Zhao, H | 1 |
| Ankati, H; Biehl, ER; Hua, L; Yang, Y; Zhu, D | 1 |
| Enderlin, G; Nielsen, P | 1 |
| Meldal, M; Tornøe, CW | 1 |
| Keillor, JW; Lubell, WD; Pardin, C; Roy, I | 1 |
| Chittepu, P; Seela, F; Sirivolu, VR | 1 |
| Brik, A; Cauvi, G; Elder, JH; Giffin, MJ; Heaslet, H; Lin, YC; McRee, DE; Stout, CD; Torbett, BE; Wong, CH | 1 |
| Díez-González, S; Nolan, SP; Stevens, ED | 1 |
| Chen, M; Fang, L; Kedenburg, JP; Liu, X; Shen, J; Sun, D; Wang, PG; Woodward, R | 1 |
| Brimble, MA; Choi, KW | 1 |
| Balducci, E; Bellucci, L; Petricci, E; Taddei, M; Tafi, A | 1 |
| Girard, C; Herscovici, J; Jlalia, I; Meganem, F | 1 |
| Carlmark, A; Hawker, C; Hult, A; Malkoch, M | 1 |
| Kumarraja, M; Namitharan, K; Pitchumani, K | 1 |
| Moses, JE; Zhang, F | 1 |
| Endo, A; Hirose, T; Iguchi, K; Omura, S; Sharpless, KB; Shiomi, K; Sugawara, A; Sunazuka, T; Ui, H; Watanabe, T; Yamamoto, T | 1 |
| Achari, B; Chowdhury, C; Das, B; Mukherjee, S | 1 |
| Chandrasekaran, S; Nasir Baig, RB; Phani Kumar, NY; Sai Sudhir, V | 1 |
| Fokin, VV; Hein, JE; Krasnova, LB; Sharpless, KB; Tripp, JC | 1 |
| Brotherton, WS; Clark, RJ; Dalal, NS; Michaels, HA; Simmons, JT; Zhu, L | 1 |
| Moses, JE; Spiteri, C | 1 |
| Attanasi, OA; Favi, G; Filippone, P; Mantellini, F; Moscatelli, G; Perrulli, FR | 1 |
| Ma, Y; Ni, BB; Pei, J; Wang, C; Wu, H | 1 |
| Campbell-Verduyn, LS; Dierckx, RA; Elsinga, PH; Feringa, BL; Janssen, DB; Postema, CP; Szymański, W | 1 |
| Lecourt, T; Micouin, L; Zhou, Y | 1 |
| Banday, AH; Gupta, BD; Kumar, HM; Shameem, SA | 1 |
| Neudörfl, JM; Nicolaus, N; Oschkinat, H; Prokop, A; Riesterer, P; Schmalz, HG; Zapke, J | 1 |
| Holub, JM; Kirshenbaum, K | 1 |
| Andrade, P; Campo, VL; Carvalho, I; Dedola, S; Field, RA; Guedes, PM; Hill, L; Nepogodiev, SA; Rejzek, M; Schenkman, S; Sesti-Costa, R; Silva, JS | 1 |
| Chattopadhyay, B; Chuprakov, S; Gevorgyan, V; Vera, CI | 1 |
| Boerman, OC; Dijkgraaf, I; Eek, A; Liskamp, RM; Merkx, R; Mulder, GE; Rijkers, DT; Versluis, C; Yim, CB | 1 |
| Fokin, VV; Kalisiak, J; Radić, Z; Sharpless, KB; Taylor, P | 1 |
| Dedola, S; Field, RA; Hughes, DL; Nepogodiev, SA; Rejzek, M | 1 |
| Barluenga, S; Chouikhi, D; Winssinger, N | 1 |
| Lam, JW; Qin, A; Tang, BZ | 1 |
| Pandey, SK; Singh, N; Tripathi, RP | 1 |
| Lee, LA; Li, K; Lu, X; Wang, Q | 1 |
| Finn, MG; Kasuya, Y; Kawamura, Y; Miyata, N; Mutsuga, M; Nakagawa, H; Ota, Y; Suzuki, T; Tsumoto, H | 1 |
| Bianchini, F; Bottoncetti, A; Calorini, L; Cini, N; Guarna, A; Menchi, G; Pupi, A; Raspanti, S; Trabocchi, A | 1 |
| Bol'shakov, O; El Khatib, M; Katritzky, AR; Khelashvili, L; Steel, PJ | 1 |
| Bernard, J; Besset, C; Drockenmuller, E; Fleury, E; Pascault, JP | 1 |
| Hu, Y; Shao, C; Wang, X; Xu, J; Zhang, Q; Zhao, J | 1 |
| Boons, GJ; Friscourt, F | 1 |
| Aguilar-Aguilar, A; Geyer, K; Lautens, M; Panteleev, J; Wang, L | 1 |
| Albohy, A; Cairo, CW; Sandbhor, M; Zou, Y | 1 |
| Bogdan, AR; James, K | 1 |
| Chibale, K; Egan, TJ; Guantai, EM; Gut, J; Ncokazi, K; Rosenthal, PJ; Smith, PJ | 1 |
| Cohrt, AE; Jensen, JF; Nielsen, TE | 1 |
| Elayadi, H; Lazrek, HB; Leyssen, P; Neyts, J; Pannecouque, C; Smietana, M; Vasseur, JJ | 1 |
| Besanceney, C; Jiang, H; Levy, M; Liu, Y; Marlow, FL; Soriano Del Amo, D; Wang, W; Wu, P; Yan, AC | 1 |
| Doak, BC; Scanlon, MJ; Simpson, JS | 1 |
| Akabane, M; Hari, Y; Kuboyama, T; Nakahara, M; Obika, S; Pang, J | 1 |
| Assali, M; Fernández, I; Khiar, N; Leal, MP | 1 |
| Cai, C; Kumar, A; Li, K | 1 |
| Nielsen, TE; Qvortrup, K | 1 |
| Kumar, R; Pradhan, P; Zajc, B | 1 |
| Boonnak, R; de Esch, IJ; de Graaf, C; de Kloe, G; Istyastono, EP; Jongejan, A; Leurs, R; Lim, H; Nijmeijer, S; Smit, J; Smits, RA; Wijtmans, M; Zuiderveld, O | 1 |
| Canalle, LA; Overhand, M; van der Knaap, M; van Hest, JC | 1 |
| Charavgi, MD; Chrysina, ED; Czecze, L; Docsa, T; Gergely, P; Kun, S; Nagy, GZ; Patonay, T; Skourti, PV; Somsák, L; Tóth, M; Van Nhien, AN | 1 |
| Breslin, MJ; Coleman, PJ; Cox, CD; Cui, D; Doran, SM; Fox, SV; Garson, SL; Gotter, AL; Harrell, CM; Reiss, DR; Renger, JJ; Stevens, J; Tannenbaum, PL; Winrow, CJ | 1 |
| Abdelmounim, S; Bentabed-Ababsa, G; Derdour, A; Domingo, LR; Mongin, F; Nassar, E; Roisnel, T; Sáez, JA; Zeghada, S | 1 |
| Heine, A; Klebe, G; Koert, U; Linne, U; Sandner, NU; Sun, D; Wischeler, JS | 1 |
| Auer, AA; Banert, K; Firdous, S | 1 |
| Praneeth, K; Subba Reddy, BV; Yadav, JS | 1 |
| Chouhan, G; James, K | 1 |
| Camp, D; Campitelli, M; Hegde, V; Quinn, RJ | 1 |
| Gupta, S; Krishna, DG; Kundu, B; Mandadapu, AK; Sharma, SK | 1 |
| Agrofoglio, LA; Coats, SJ; Herman, BD; Obikhod, A; Roy, V; Schinazi, RF; Sluis-Cremer, N; Zhang, HW | 1 |
| Dorsch, D; Grädler, U; Greiner, HE; Klukas, F; Merkul, E; Müller, TJ | 1 |
| Basso, A; Crosignani, S; De Moliner, F; Galatini, A; Riva, R | 1 |
| Kurumurthy, C; Narsaiah, B; Pamanji, R; Sambasiva Rao, P; Santhosh Kumar, G; Shanthan Rao, P; Veera Swamy, B; Velatooru, LR; Venkateswara Rao, J | 1 |
| Boons, GJ; Guo, J; Mbua, NE; Steet, R; Wolfert, MA | 1 |
| Chen, JZ; Ding, W; Giulianotti, MA; Han, S; Jia, P; Medina-Franco, JL; Ou, L; Yang, B; Yu, Y | 1 |
| Andemarian, F; Donnelly, PS; Khairallah, GN; O'Hair, RA; Proietti Silvestri, I; Quach, T; Tsegay, S; Williams, CM; Williams, SJ; Yap, SW | 1 |
| Dendane, N; Ebran, JP; Melnyk, O | 1 |
| Culhane, JC; Fokin, VV | 1 |
| Chen, H; Chen, L; Li, T; Liu, D; Liu, J; Liu, Y; Lu, Y; Tang, X; Wang, X; Zhang, S; Zhao, M; Zuo, S | 1 |
| Butters, TD; Diot, JD; Garcia Moreno, I; Gouin, SG; Haupt, K; Kovensky, J; Ortiz Mellet, C; Twigg, G | 1 |
| Görls, H; Hager, MD; Jahn, BO; Kloss, F; Köhn, U; Schubert, US | 1 |
| Hagel, G; Ishoey, M; Le Quement, ST; Nielsen, TE; Petersen, MT; Thastrup, J | 1 |
| Agalave, SG; Maujan, SR; Pore, VS | 1 |
| Michaels, HA; Zhu, L | 1 |
| Chen, B; Chen, Y; Li, N; Liu, X; Wang, D; Zhao, M | 1 |
| Nagarajan, S; Ponnuswamy, A; Sathishkumar, M; Shanmugavelan, P; Sriram, D; Yogeeswari, P | 1 |
| François, B; Pierre-Antoine, F; Rachida, Z | 1 |
| Babu, TH; Kumar, BV; Perumal, PT; Rajeswari, C | 1 |
| Aucagne, V; Delmas, AF; Lalmanach, G; Lecaille, F; Valverde, IE | 1 |
| Campo, VL; Carneiro, ZA; Carvalho, I; Schenkman, S; Sesti-Costa, R; Silva, JS | 1 |
| Coleska, A; Kawamoto, SA; Ran, X; Wang, S; Yang, CY; Yi, H | 1 |
| Guo, ZF; Li, ZF; Lu, ZL; Wang, F; Wu, LZ; Yan, H | 1 |
| Brimble, MA; Choi, KW; Kueh, JT | 1 |
| Desaulniers, JP; Efthymiou, TC; Huynh, V; Oentoro, J; Peel, B | 1 |
| Donald, JR; Martin, SF; Wood, RR | 1 |
| Abrahám, A; Fekete, S; Kónya, K; Patonay, T | 1 |
| Coudane, J; Darcos, V; Guillerm, B; Lapinte, V; Monge, S; Robin, JJ | 1 |
| Bahulayan, D; Pramitha, P | 1 |
| Boons, GJ; Chen, G; Guo, J; Jagielska, A; Li, X; Ning, X; Xu, B; Zhou, J | 1 |
| Cheng, C; Hu, Y; Liu, N; Wang, X; Zhang, Q; Zhu, R | 1 |
| McConville, MJ; Ralton, JE; van der Peet, P; Williams, SJ | 1 |
| Bergmeier, SC; Fang, F; Hines, JV; Vogel, M | 1 |
| Amiri, M; Khalili, E; Valizadeh, H | 1 |
| Abbas, M; Brauch, S; Gabriel, L; Henze, M; Stark, S; van Berkel, SS; Vasilev, D; Wessjohann, LA; Westermann, B | 1 |
| Cavalcante, NN; dos Anjos, JV; Lima-Neto, RG; Mendonça Junior, FJ; Neves, RP; Srivastava, RM; Wanderley, AG | 1 |
| Jia, G; Liu, PN; Siyang, HX; Tse, SK; Zhang, L | 1 |
| Guggenheim, KG; Kurth, MJ; Toru, H | 1 |
| Brotherton, WS; Clark, RJ; Zhu, L | 1 |
| Dufouil, M; Fokin, VV; Fotsing, JR; Gomez, K; Grimster, N; Ho, KY; Nemecz, A; Sharpless, KB; Talley, TT; Taylor, P; Yamauchi, JG | 1 |
| Anand, A; Bedi, PM; Kaur, T; Kumar, V; Saxena, AK; Sharma, P; Singh, P | 1 |
| Liu, R; Tang, W; Winston-McPherson, G; Zhang, M | 1 |
| Brimble, MA; Lee, DJ; Williams, GM; Yang, SH | 1 |
| Atherton, JH; Ji, P; Page, MI | 1 |
| Barbosa, LA; Barison, A; da Silva, GD; da Silva, MG; Simões, SC; Souza, EM; Varotti, FP; Viana, GH; Villar, JA | 1 |
| Akula, HK; Lakshman, MK | 1 |
| Lai, GQ; Xu, LW; Yang, KF; Ye, F; Zheng, LS; Zheng, ZJ | 1 |
| Ingale, SA; Seela, F | 1 |
| Ghule, VD; Muralidharan, K; Srinivas, D; Tewari, SP | 1 |
| Jiao, N; Ma, JA; Wang, T; Yin, H; Zhou, W | 1 |
| Boons, GJ; Fahrni, CJ; Friscourt, F | 1 |
| Biot, C; Carrère-Kremer, S; Guérardel, Y; Kremer, L; Kumar, K; Kumar, V | 1 |
| Chen, GR; Chen, K; Cheng, CY; He, XP; Shi, DT; Xie, J; Xue, JL; Yang, JW | 1 |
| Goyard, D; Praly, JP; Vidal, S | 1 |
| Amini, M; Ebrahimi, SE; Erfani, M; Hassanzadeh, L; Najafi, R; Shafiee, A; Shafiei, M | 1 |
| Chromiński, M; Gryko, D | 1 |
| Ichikawa, S; Matsuda, A; Sato, K; Sunadome, T; Ueno, H | 1 |
| Fülöp, F; Kiss, L; Mándity, IM; Ötvös, SB | 1 |
| Cai, YB; Liang, L; Sun, HL; Zhang, J; Zhang, JL | 1 |
| Camara, CA; da Silva, EN; de Melo, IM; de Oliveira, RN; Diogo, EB; do Monte-Neto, RL; Ferreira, VF; Frézard, F; Guimarães, TT; Lanza, JS; Melo, MN; Pinto, Mdo C; Valença, WO | 1 |
| Lim, D; Park, SB | 1 |
| Kemmink, J; Liskamp, RM; Rijkers, DT; Zhang, J | 1 |
| Alonso, F; Moglie, Y; Radivoy, G; Yus, M | 1 |
| Hong, L; Lin, W; Liu, R; Zhang, F; Zhou, X | 1 |
| Bai, SQ; Hor, TS; Jiang, L; Wang, Z | 1 |
| Azuaje, J; Caamaño, O; Coelho, A; Diz, PM; El Maatougui, A; Gil, Á; Sotelo, E | 1 |
| Ahn, JS; Bond, MR; Ghosh, S; Hanover, JA; Kang, DO; Kang, DW; Kim, EJ; Leucke, HF; Love, DC | 1 |
| Biyajima, T; Hiraga, K; Miura, T; Murakami, M; Nakamuro, T | 1 |
| Astruc, D; Ruiz, J; Salmon, L; Wang, D | 1 |
| Chen, H; Ding, C; Shen, Q; Wang, T; White, MA; Wild, C; Zhang, Y; Zhou, J | 1 |
| Barros, MT; Petrova, KT; Potewar, TM | 1 |
| Cheng, YY; Clady, RG; Goldstein, DC; Peterson, JR; Schmidt, TW; Thordarson, P | 1 |
| Kumar, R; Singh, G; Swett, J; Zajc, B | 1 |
| Jha, A; Khungar, B; Kumar, A; Pericherla, K | 1 |
| Kurth, MJ; Nguyen, HH; Palazzo, TA | 1 |
| Hiraga, K; Miura, T; Murakami, M; Stewart, SG; Tanaka, T | 1 |
| Greaney, MF; Smith, CD | 1 |
| Bouriaud, A; Chaumontet, M; Kolodych, S; Rasolofonjatovo, E; Taran, F; Theeramunkong, S | 1 |
| Ramachary, DB; Shashank, AB | 1 |
| Gouda, H; Hirono, S; Hirose, T; Koseki, J; Maita, N; Nakano, H; Omura, S; Sharpless, KB; Shiomi, K; Sugawara, A; Sunazuka, T; Taniguchi, H; Watanabe, T; Yamamoto, T | 1 |
| Bouhss, A; Calvet-Vitale, S; Fer, MJ; Gravier-Pelletier, C; Olatunji, S | 1 |
| Du, Z; Jia, Q; Li, W; Wang, J | 1 |
| Kumar, K; Loganathan, D; Sahoo, L; Singhamahapatra, A | 1 |
| Fan, X; Hao, G; Li, L; Zhang, G; Zhang, L; Zhu, A | 1 |
| Ellery, SP; Fokin, VV; Worrell, BT | 1 |
| Rudolf, GC; Sieber, SA | 1 |
| Anireddy, J; Devi, YP; Kapavarapu, R; Mangamoori, LN; Mareddy, J; Nallapati, SB; Pal, S | 1 |
| Bullock, RM; Das, AK; Engelhard, MH; Liu, F; Roberts, JA | 1 |
| Aldeco-Pérez, E; Cuevas-Yañez, E; Ortega-Arizmendi, AI | 1 |
| Ansari, MI; Hajela, K; Hussain, MK; Kant, R | 1 |
| Behl, G; Chhikara, A; Chopra, M; Sikka, M | 1 |
| Brunco, A; Massarotti, A; Sorba, G; Tron, GC | 1 |
| Akkenapally, S; Deora, GS; Durgadas, S; Ganesh Kumar, C; Mukkanti, K; Murthy, NY; Pal, S; Praveena, KS; Suresh Babu, N | 1 |
| Arantes, LM; Brandão, GC; da Rocha, RK; de Oliveira, AB; de Oliveira, HA; de Paula, RC; do Nascimento, MF; dos Santos, FM; Lopes, JC; Pereira, GR | 1 |
| Brycki, B; Koenig, H; Kowalczyk, I; Pospieszny, T | 1 |
| Astruc, D; Echeverria, M; Etienne, L; Moya, S; Wang, D | 1 |
| Khurana, JM; Sindhu, J; Singh, H | 1 |
| Leitner, K; Ringwald, M; Schmidt, MS; Welter, M; Wurmthaler, LA | 1 |
| Ali, A; Goswami, A; Nayak, D; Sharma, PR; Vishwakarma, RA; Zilla, MK | 1 |
| Aubé, J; Liu, R; Vekariya, RH | 1 |
| Braslau, R; Earla, A | 1 |
| Eom, D; Kim, CE; Lee, PH; Park, S; Seo, B | 1 |
| Dey, S; Ganguly, B; Pathak, T; Sahu, D | 1 |
| Huang, FP; Pan, YM; Qu, HE; Wang, HS; Wang, YC; Xie, YY | 1 |
| Choi, W; Jeon, WH; Lee, PH; Min, J; Ryu, T | 1 |
| Mishra, KB; Tiwari, VK | 1 |
| Achari, B; Chattopadhyay, P; Ghorai, A; Reddy K, S | 1 |
| Estrada Girona, G; Herner, A; Kállay, M; Kele, P; Lemke, EA; Nikić, I | 1 |
| Adiyala, PR; Chandrasekhar, D; Kamal, A; Kapure, JS; Maurya, RA; Reddy, CN | 1 |
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22 review(s) available for azides and triazoles
| Article | Year |
|---|---|
Recent trends in the synthesis of O-glycosides of 2-amino-2-deoxysugars.
Topics: Amides; Amino Sugars; Aminoglycosides; Azides; Carbamates; Epoxy Compounds; Phthalimides; Sulfonic Acids; Triazoles | 2007 |
The growing applications of click chemistry.
Topics: Alkynes; Azides; Catalysis; Combinatorial Chemistry Techniques; Copper; Cross-Linking Reagents; Drug Design; Triazoles | 2007 |
Click chemistry reactions in medicinal chemistry: applications of the 1,3-dipolar cycloaddition between azides and alkynes.
Topics: Alkynes; Azides; Catalysis; Combinatorial Chemistry Techniques; Copper; Cyclization; Dimerization; Drug Design; HIV Protease Inhibitors; Macrocyclic Compounds; Triazoles | 2008 |
Cu-catalyzed azide-alkyne cycloaddition.
Topics: Alkynes; Azides; Catalysis; Copper; Crystallography, X-Ray; Cyclization; Dendrimers; Ligands; Models, Molecular; Molecular Structure; Organometallic Compounds; Stereoisomerism; Triazoles | 2008 |
New methodologies in the construction of dendritic materials.
Topics: Alkenes; Azides; Catalysis; Dendrimers; Stereoisomerism; Triazoles | 2009 |
Tricks with clicks: modification of peptidomimetic oligomers via copper-catalyzed azide-alkyne [3 + 2] cycloaddition.
Topics: Alkynes; Azides; Biomimetic Materials; Catalysis; Copper; Cyclization; Polymers; Triazoles | 2010 |
Click polymerization.
Topics: Alkynes; Azides; Catalysis; Copper; Fluorescence; Triazoles | 2010 |
Click chemistry: 1,2,3-triazoles as pharmacophores.
Topics: Alkynes; Azides; Catalysis; Click Chemistry; Copper; Cyclization; Drug Discovery; Pharmaceutical Preparations; Triazoles | 2011 |
Computational studies on the regioselectivity of metal-catalyzed synthesis of 1,2,3 triazoles via click reaction: a review.
Topics: Alkynes; Azides; Catalysis; Click Chemistry; Computer Simulation; Cycloaddition Reaction; Metals; Models, Chemical; Triazoles | 2015 |
Carbohydrate CuAAC click chemistry for therapy and diagnosis.
Topics: Alkynes; Anti-Infective Agents; Antineoplastic Agents; Azides; Carbohydrates; Catalysis; Chemistry, Pharmaceutical; Click Chemistry; Cycloaddition Reaction; Glycosylation; Humans; Imino Sugars; Neoplasms; Signal Transduction; Triazoles | 2016 |
Medicinal attributes of 1,2,3-triazoles: Current developments.
Topics: Alkynes; Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Antineoplastic Agents; Azides; Click Chemistry; Cycloaddition Reaction; Cyclooxygenase Inhibitors; Drug Discovery; HIV Protease Inhibitors; Humans; Models, Molecular; Receptor, Cannabinoid, CB1; Triazoles | 2017 |
The potential of click reactions for the synthesis of bioactive triterpenes.
Topics: Alkynes; Antiprotozoal Agents; Azides; Catalysis; Cell Survival; Click Chemistry; Cycloaddition Reaction; Humans; Triazoles; Triterpenes | 2019 |
Exploiting azide-alkyne click chemistry in the synthesis, tracking and targeting of platinum anticancer complexes.
Topics: Alkynes; Antineoplastic Agents; Azides; Cellular Microenvironment; Click Chemistry; Copper; Cycloaddition Reaction; Drug Development; Drug Resistance; Fluorescent Dyes; Gold; Humans; Ligands; Molecular Structure; Organometallic Compounds; Platinum; Triazoles | 2020 |
Reactive & Efficient: Organic Azides as Cross-Linkers in Material Sciences.
Topics: Alkynes; Azides; Catalysis; Cross-Linking Reagents; Cycloaddition Reaction; Humans; Materials Science; Molecular Structure; Nitrogen; Photochemical Processes; Photolysis; Triazoles | 2020 |
Synthetic approaches towards bedaquiline and its derivatives.
Topics: Alkynes; Animals; Antitubercular Agents; Azides; Catalysis; Cycloaddition Reaction; Diarylquinolines; Drug Evaluation, Preclinical; Humans; Molecular Structure; Mycobacterium tuberculosis; Stereoisomerism; Structure-Activity Relationship; Triazoles; Tuberculosis, Multidrug-Resistant | 2020 |
Modified Nucleosides, Nucleotides and Nucleic Acids via Click Azide-Alkyne Cycloaddition for Pharmacological Applications.
Topics: Adenosine; Alkynes; Animals; Azides; Cell Line, Tumor; Click Chemistry; Cycloaddition Reaction; DNA; ErbB Receptors; Humans; Mice; Nucleic Acids; Nucleosides; Nucleotides; Oligonucleotides, Antisense; Reproducibility of Results; RNA, Guide, Kinetoplastida; Technology, Pharmaceutical; Triazoles | 2021 |
An Overview of Recent Advances in Biomedical Applications of Click Chemistry.
Topics: Alkynes; Animals; Anti-Infective Agents; Antineoplastic Agents; Azides; Catalysis; Click Chemistry; Copper; Cycloaddition Reaction; Diagnostic Imaging; Drug Discovery; Humans; Triazoles | 2021 |
A minireview of 1,2,3-triazole hybrids with O-heterocycles as leads in medicinal chemistry.
Topics: Azides; Chemistry, Pharmaceutical; Cycloaddition Reaction; Drug Design; Molecular Structure; Structure-Activity Relationship; Triazoles | 2022 |
An Overview on the Performance of 1,2,3-Triazole Derivatives as Corrosion Inhibitors for Metal Surfaces.
Topics: Azides; Catalysis; Click Chemistry; Corrosion; Cycloaddition Reaction; Metals; Molecular Structure; Surface Properties; Triazoles | 2021 |
Recent Advances in Copper-Based Solid Heterogeneous Catalysts for Azide-Alkyne Cycloaddition Reactions.
Topics: Alkynes; Azides; Catalysis; Click Chemistry; Copper; Cycloaddition Reaction; Triazoles | 2022 |
Comprehensive review on natural pharmacophore tethered 1,2,3-triazoles as active pharmaceuticals.
Topics: Alkynes; Azides; Catalysis; Click Chemistry; Copper; Cycloaddition Reaction; Pharmaceutical Preparations; Pharmacophore; Triazoles | 2023 |
Advances in the Synthesis of Fused 1,2,3-Triazoles via a MCR-Intramolecular Azide-Alkyne Cycloaddition Approach.
Topics: Alkynes; Azides; Catalysis; Cycloaddition Reaction; Molecular Structure; Triazoles | 2022 |
433 other study(ies) available for azides and triazoles
| Article | Year |
|---|---|
Catalase activity in methanol-oxidizing Candida boidinii 11 Bh and its cytochemical localization.
Topics: Alcohol Oxidoreductases; Azides; Candida; Catalase; Cyanides; Histocytochemistry; Hydrogen-Ion Concentration; Kinetics; Methanol; Microscopy, Electron; Subcellular Fractions; Triazoles | 1975 |
Interference of azide with cysteine biosynthesis in Salmonella typhimurium.
Topics: Azides; Chromosome Mapping; Cross Reactions; Cysteine; Drug Resistance, Microbial; Mutation; Oxidoreductases Acting on Sulfur Group Donors; Salmonella typhimurium; Triazoles | 1979 |
Photosynthetically-linked oxidation of diaminobenzidine in Blue-green algae.
Topics: 3,3'-Diaminobenzidine; Aminobiphenyl Compounds; Antimycin A; Azides; Chloroplasts; Cyanides; Cyanobacteria; Darkness; Dinitrophenols; Diuron; Dose-Response Relationship, Drug; Electron Transport; Hydrogen Peroxide; Light; Photosynthesis; Potassium; Sodium; Triazoles | 1975 |
Inhibition by metal-chelating agents and by catalase of arachidonic acid-induced platelet aggregation.
Topics: Adenosine Diphosphate; Animals; Anti-Inflammatory Agents; Arachidonic Acids; Azides; Catalase; Chelating Agents; Cyclooxygenase Inhibitors; Dogs; Peroxides; Platelet Aggregation; Rabbits; Sulfhydryl Compounds; Triazoles | 1976 |
Estrogen binding by leukocytes during phagocytosis,.
Topics: Azides; Catalase; Cyanides; Estradiol; Humans; Neutrophils; Phagocytosis; Superoxide Dismutase; Triazoles | 1977 |
Comparative studies on hepatic dimethylnitrosamine demethylase and some xenobiotic-metabolizing enzymes in the rat.
Topics: Aniline Hydroxylase; Animals; Azides; Cyanides; Dimethylnitrosamine; Ethylmorphine-N-Demethylase; Kinetics; Metyrapone; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases, N-Demethylating; Proadifen; Pyrazoles; Rats; Time Factors; Triazoles | 1975 |
Effect of chemicals used as nitrification inhibitors on the denitrification process.
Topics: Anaerobiosis; Aniline Compounds; Azides; Mercury; Nitrates; Organometallic Compounds; Pseudomonas; Pyridines; Pyrimidines; Soil Microbiology; Sulfanilamides; Thiazoles; Triazoles | 1976 |
The fine structural localization of endogenous and exogenous peroxidase activity in Kupffer cells of rat liver.
Topics: Aldehydes; Animals; Azides; Cyanides; Cytoplasmic Granules; Endoplasmic Reticulum; Golgi Apparatus; Histocytochemistry; Hydrogen Peroxide; Inclusion Bodies; Liver; Lysosomes; Male; Microscopy, Electron; p-Dimethylaminoazobenzene; Peroxidases; Phagocytosis; Pinocytosis; Rats; Staining and Labeling; Triazoles | 1970 |
Ultrastructural localization of oxidase activities in corn root tip cells with two new osmiophilic reagents compared to diaminobenzidine.
Topics: Amines; Azides; Biphenyl Compounds; Catalase; Cell Membrane; Cell Nucleus; Chemical Phenomena; Chemistry; Cyanides; Endoplasmic Reticulum; Ethylenediamines; Glutarates; Histocytochemistry; Hot Temperature; Microscopy, Electron; Mitochondria; Osmium; Oxidoreductases; Peroxidases; Staining and Labeling; Triazoles; Xylenes; Zea mays | 1971 |
Lipid peroxidation in erythrocytes. Supravital staining of peroxidised cells by crystal violet.
Topics: Aldehydes; Azides; Catalase; Cell Membrane; Erythrocytes; Gentian Violet; Glutathione; Hemolysis; Humans; Hydrogen Peroxide; Lipid Metabolism; Malonates; Peroxidases; Sodium; Staining and Labeling; Triazoles | 1974 |
Cytochemical localization of peroxidatic activity of catalase in rat hepatic microbodies (peroxisomes).
Topics: Animals; Azides; Biphenyl Compounds; Catalase; Cyanides; Histocytochemistry; Hydrogen Peroxide; Hydrogen-Ion Concentration; Liver; Male; Membranes; Microsomes; p-Dimethylaminoazobenzene; Permeability; Peroxidases; Pyruvates; Rats; Staining and Labeling; Triazoles | 1969 |
Distribution of peroxidase activity in Tetrahymena pyriformis mitochondria.
Topics: Animals; Azides; Biphenyl Compounds; Cyanides; Diamines; Drug Stability; Ferricyanides; Histocytochemistry; Hot Temperature; Kinetics; Membranes; Microscopy, Electron; Mitochondria; Nitro Compounds; Peroxidases; Tetrahymena pyriformis; Time Factors; Triazoles | 1974 |
Hepatic microsomal ethanol-oxidizing system. In vitro characteristics and adaptive properties in vivo.
Topics: Alcohol Oxidoreductases; Animals; Azides; Carbon Monoxide; Catalase; Cyanides; Diet; Drug Tolerance; Endoplasmic Reticulum; Ethanol; Humans; Hydrogen-Ion Concentration; Microsomes, Liver; NAD; Oxygen; Pyrazoles; Rats; Triazoles | 1970 |
Oxidative decarboxylation of glycollate and glyoxylate by leaf peroxisomes.
Topics: Animals; Azides; Carbon Dioxide; Carbon Radioisotopes; Catalase; Cattle; Cell Fractionation; Centrifugation, Density Gradient; Chromatography, Paper; Decarboxylation; Edetic Acid; Flavin Mononucleotide; Glycolates; Glyoxylates; Hydrogen-Ion Concentration; Kinetics; Mercaptoethanol; Mesylates; Microbodies; Plant Cells; Plants; Subcellular Fractions; Surface-Active Agents; Thiamine Pyrophosphate; Triazoles | 1974 |
Ethanol oxidation in the microsomal fraction of rat liver.
Topics: Acetaldehyde; Animals; Azides; Biphenyl Compounds; Carbon Monoxide; Catalase; Cattle; Cyanides; Cytochromes; Depression, Chemical; Ethanol; Glucose; Glucose Oxidase; Liver; Male; Microsomes; NADP; Peroxides; Proadifen; Rats; Stimulation, Chemical; Triazoles | 1969 |
The role of microsomes in the hepatic metabolism of ethanol.
Topics: Acetates; Adenine Nucleotides; Aerobiosis; Amino Alcohols; Anaerobiosis; Animals; Azides; Bile Acids and Salts; Carbon Monoxide; Catalase; Cell Fractionation; Chlorides; Chloromercuribenzoates; Copper; Cyanides; Diet; Dimethyl Sulfoxide; Edetic Acid; Ethanol; Female; Hot Temperature; Hydrogen Peroxide; Iron; Liver; Mercury; Microsomes, Liver; NAD; NADP; Oxidoreductases; Phenobarbital; Pyrazoles; Rats; Sulfides; Triazoles | 1971 |
Metabolism of ethanol by rat liver microsomal enzymes.
Topics: Amines; Animals; Azides; Barium; Bile Acids and Salts; Cyanides; Digitalis Glycosides; Ethanol; Hydrogen Peroxide; Hydrogen-Ion Concentration; Kinetics; Male; Metabolism; Microsomes, Liver; NADP; Oxides; Potassium; Proadifen; Pyrazoles; Rats; Saponins; Sodium; Spirostans; Triazoles; Ultracentrifugation | 1970 |
Microbodies (peroxisomes) in the interstitial cells of rodent testes.
Topics: Acid Phosphatase; Aldehydes; Amines; Androgens; Animals; Azides; Biphenyl Compounds; Cholesterol; Clofibrate; Cyanides; Guinea Pigs; Histocytochemistry; Hydrogen-Ion Concentration; Inclusion Bodies; Leydig Cells; Male; Mice; Microscopy, Electron; NADP; Osmium; Peroxidases; Pyruvates; Rats; Rats, Inbred Strains; Triazoles | 1972 |
A suggested role for hydrogen peroxide in the biosynthesis of prostaglandins.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acids; Azides; Carbon Radioisotopes; Catalase; Cattle; Chlorpromazine; Chromatography, Thin Layer; Depression, Chemical; Hydrogen Peroxide; Male; Methods; Microsomes; Platelet Aggregation; Prostaglandins; Seminal Vesicles; Time Factors; Triazoles | 1974 |
Molecular location of the genetic lesion in the acatalasemic mouse.
Topics: Animals; Azides; Catalase; Chromatography, Ion Exchange; Drug Stability; Goats; Guanidines; Heme; Hydroxylamines; Immune Sera; Liver; Mice; Mutation; Protein Conformation; Protein Denaturation; Rabbits; Triazoles; Trypsin; Urea | 1972 |
The formation of biliverdin by chicken macrophages in tissue culture. Observations on the effect of inhibitors.
Topics: Acetanilides; Animals; Ascorbic Acid; Azides; Bile Pigments; Carbon Monoxide; Chickens; Chloramphenicol; Culture Techniques; Cyanides; Cycloheximide; Dactinomycin; Erythrocytes; Ethylmaleimide; Female; Heme; Hydrogen Peroxide; Macrophages; Metabolism; Microscopy, Phase-Contrast; Mitomycins; Phagocytosis; Phenobarbital; Proadifen; Quinacrine; Spectrophotometry; Spectrum Analysis; Stimulation, Chemical; Triazoles | 1970 |
Role of the phagocyte in host-parasite interactions. XII. Hydrogen peroxide-myeloperoxidase bactericidal system in the phagocyte.
Topics: Animals; Azides; Bacillus subtilis; Bacteria; Cyanides; Enterococcus faecalis; Escherichia coli; Guinea Pigs; Hydrogen Peroxide; Hydrogen-Ion Concentration; Leukocytes; Listeria monocytogenes; Neutrophils; Peroxidases; Phagocytosis; Pseudomonas aeruginosa; Shigella sonnei; Staphylococcus; Streptococcus pyogenes; Triazoles | 1967 |
Protective factors in the detoxication of hydrogen peroxide in erythrocytes.
Topics: Animals; Azides; Carbon Isotopes; Catalase; Cats; Cattle; Cysteine; Dogs; Erythrocytes; Ethylmaleimide; Glucose; Glutathione; Goats; Guinea Pigs; Haplorhini; Hemoglobins; Hexosephosphates; Humans; Hydrogen Peroxide; Lactates; Methemoglobin; Rabbits; Sulfhydryl Compounds; Triazoles | 1969 |
Acatalasemia in the mouse and other species.
Topics: Animals; Antigen-Antibody Reactions; Azides; Catalase; Cattle; Chickens; Erythrocytes; Heterozygote; Horses; Hot Temperature; Immunodiffusion; Metabolism, Inborn Errors; Mice; Molecular Biology; Pedigree; Protein Denaturation; Radiation Injuries, Experimental; Sheep; Species Specificity; Triazoles; Urea | 1970 |
Ultrastructural localization of peroxidase activity in human platelets and megakaryocytes.
Topics: Aniline Compounds; Azides; Biphenyl Compounds; Blood Platelets; Cyanides; Endoplasmic Reticulum; Histocytochemistry; Humans; Megakaryocytes; Microscopy, Electron; Peroxidases; Triazoles | 1972 |
Preparation of 5-amino-1H,1,2,3-triazole-4-carboxamide.
Topics: Amides; Azides; Triazoles | 1970 |
Pyrimidines. IX. A new synthesis of 8-azapurines and v-triazolo[4,5-b]pyridines.
Topics: Azaguanine; Azides; Chemical Phenomena; Chemistry; Chromatography; Deuterium; Dimethyl Sulfoxide; Magnetic Resonance Spectroscopy; Purines; Pyridines; Pyrimidines; Triazoles | 1970 |
Heterocyclic compounds from urea derivatives. XVI. Interaction of carbohydrazide and carbodi-imides.
Topics: Azides; Chemical Phenomena; Chemistry; Dimethyl Sulfoxide; Formamides; Heterocyclic Compounds; Imides; Triazoles; Urea | 1970 |
[Heterocyclic compounds from urea derivatives. XVII. Reactions of l-phenylcarbonohydrazide and l-phenylthiocarbonohydrazide with carbodi-imides].
Topics: Azides; Chemical Phenomena; Chemistry; Heterocyclic Compounds; Imides; Nitroso Compounds; Phenylhydrazines; Triazoles; Urea | 1970 |
Glutathione and the hexose monophosphate shunt in phagocytizing and hydrogen peroxide-treated rat leukocytes.
Topics: Animals; Azides; Carbon Isotopes; Catalase; Cyanides; Depression, Chemical; Drug Synergism; Ethylmaleimide; Glucose; Glutathione; Glutathione Reductase; Hexosephosphates; Hydrogen Peroxide; Lactates; Leukocytes; Male; Peroxidases; Phagocytosis; Polystyrenes; Rats; Stimulation, Chemical; Triazoles | 1969 |
CO2 formation from formate in red blood cells.
Topics: Anemia; Animals; Azides; Carbon Dioxide; Catalase; Cyanides; Cytosine Nucleotides; Erythrocyte Aging; Erythrocytes; Formates; Hydrogen; Hydrogen Peroxide; Rabbits; Reticulocytes; Triazoles | 1967 |
Acatalasemic and hypocathalasemic mouse mutants. II. Mutational variations in blood and solid tissue catalases.
Topics: Animals; Azides; Brain; Catalase; Formamides; Guanidines; Hot Temperature; Hydrogen-Ion Concentration; Hydroxylamines; Intestines; Kidney; Liver; Lung; Metabolism, Inborn Errors; Mice; Molecular Biology; Mutation; Myocardium; Radiation Effects; Rodent Diseases; Stomach; Triazoles; Trypsin; Urea | 1967 |
Determination of selectivity of reactive nitrogen oxide species for various substrates.
Topics: Ascorbic Acid; Azides; Free Radical Scavengers; Glutathione; Indicators and Reagents; Models, Chemical; Nitrogen Oxides; Reactive Oxygen Species; Spectrometry, Fluorescence; Triazoles | 1996 |
Sedative but not anxiolytic properties of benzodiazepines are mediated by the GABA(A) receptor alpha1 subtype.
Topics: Allosteric Site; Animals; Anti-Anxiety Agents; Anticonvulsants; Azides; Benzodiazepines; Binding, Competitive; Brain; Cell Line; Diazepam; Dose-Response Relationship, Drug; Flumazenil; Fluorobenzenes; GABA-A Receptor Antagonists; Hypnotics and Sedatives; Ligands; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Motor Activity; Patch-Clamp Techniques; Receptors, GABA-A; Reflex, Startle; Triazoles | 2000 |
Assembly of functional alpha6beta3gamma2delta GABA(A) receptors in vitro.
Topics: Affinity Labels; Anesthetics; Animals; Anticonvulsants; Azides; Benzodiazepines; Binding Sites; Cells, Cultured; Desoxycorticosterone; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Membrane Potentials; Muscimol; Protein Structure, Tertiary; Rats; Receptors, GABA-A; Transfection; Triazoles; Tritium | 2000 |
Synthesis of some new 1-acylthiosemicarbazides, 1,3,4-oxadiazoles, 1,3,4-thiadiazoles and 1,2,4-triazole-3-thiones and their anti-inflammatory activities.
Topics: Air; Animals; Anti-Inflammatory Agents, Non-Steroidal; Azides; Carrageenan; Crystallization; Edema; Foot; Male; Mice; Oxadiazoles; Spectrophotometry, Ultraviolet; Thiadiazoles; Triazoles | 2001 |
A concise route to triazolobenzodiazepine derivatives via a one-pot alkyne-azide cycloaddition reaction.
Topics: Alkynes; Azides; Benzodiazepines; Carbodiimides; Chlorides; Chromatography, High Pressure Liquid; Cyclization; ortho-Aminobenzoates; Polymers; Triazoles | 2002 |
A potent and highly selective inhibitor of human alpha-1,3-fucosyltransferase via click chemistry.
Topics: Azides; Binding, Competitive; Enzyme Inhibitors; Fucosyltransferases; Guanosine Diphosphate; Humans; Hydrophobic and Hydrophilic Interactions; Kinetics; Substrate Specificity; Triazoles | 2003 |
[Study of the bacteriostatic and fungistatic effect of sodium azide and potassium cyanide].
Topics: Antifungal Agents; Azides; Cyanates; Fungicides, Industrial; Humans; Potassium Cyanide; Sodium Azide; Triazoles | 1958 |
THE OXIDATIC ACTIVITY OF HORSERADISH PEROXIDASE. I. OXIDATION OF HYDRO- AND NAPHTHOHYDROQUINONES.
Topics: Antifibrinolytic Agents; Azides; Catalase; Copper; Cyanides; Enzyme Inhibitors; Horseradish Peroxidase; Manganese; Naphthoquinones; Oxidation-Reduction; Peroxidases; Phenols; Plants, Medicinal; Polarography; Research; Spectrophotometry; Triazoles; Vitamin K | 1963 |
EFFECT ON CATALASE IN VIVO AND IN VITRO OF COMPOUNDS RELATED TO AMINOTRIAZOLE. ANL-6823.
Topics: Amitrole; Azides; Azoles; Catalase; Enzyme Inhibitors; Erythrocytes; Imidazoles; In Vitro Techniques; Isoniazid; Kidney; Liver; Oxadiazoles; Oxazoles; Oxidation-Reduction; Pentylenetetrazole; Pharmacology; Pyrazoles; Rats; Research; Thiazoles; Triazoles | 1964 |
[EXPERIMENTS ON THE DISCOVERY OF NEW FUNGISTATIC AGENTS. VII. THE ANTIMICROBIAL EFFECT OF COMPOUNDS CONTAINING ARYL-AZO-METHYLENE GROUPS].
Topics: Acetates; Acetoacetates; Amides; Anilides; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Antifungal Agents; Antitubercular Agents; Ascaris; Azides; Azo Compounds; Chemical Phenomena; Chemistry; Cyanates; Cyanides; Ketones; Malonates; Methane; Pharmacology; Research; Sulfhydryl Compounds; Thioglycolates; Triazoles; Trichomonas | 1964 |
ROLE OF CATALASES AND PEROXIDASES IN THE DEIODINATION OF THYROXINE IN FROG LIVER.
Topics: Animals; Anura; Azides; Catalase; Dialysis; Glucose Oxidase; Liver; Mice; Peroxidases; Pharmacology; Physiology, Comparative; Ranidae; Rats; Renal Dialysis; Research; Thyroxine; Triazoles | 1965 |
Direct synthesis of 1,5-disubstituted-4-magnesio-1,2,3-triazoles, revisited.
Topics: Acetylene; Alkynes; Azides; Bromides; Chemistry, Pharmaceutical; Magnesium; Molecular Structure; Triazoles | 2004 |
A fluorogenic probe for the copper(I)-catalyzed azide-alkyne ligation reaction: modulation of the fluorescence emission via 3(n,pi)-1(pi,pi) inversion.
Topics: Alkynes; Azides; Catalysis; Cations, Monovalent; Copper; Coumarins; Kinetics; Photochemistry; Spectrometry, Fluorescence; Triazoles | 2004 |
Efficiency and fidelity in a click-chemistry route to triazole dendrimers by the copper(i)-catalyzed ligation of azides and alkynes.
Topics: Alkynes; Azides; Catalysis; Copper; Macromolecular Substances; Triazoles | 2004 |
Presentation and detection of azide functionality in bacterial cell surface proteins.
Topics: Alanine; Azides; Bacterial Outer Membrane Proteins; Catalysis; Copper; Escherichia coli; Escherichia coli Proteins; Flow Cytometry; Methionine; Norleucine; Spectrometry, Fluorescence; Triazoles; Valine | 2004 |
One-pot synthesis of 1,4-disubstituted 1,2,3-triazoles from in situ generated azides.
Topics: Alkynes; Azides; Catalysis; Chemistry, Pharmaceutical; Hydrocarbons, Halogenated; Molecular Structure; Triazoles; Vinyl Compounds | 2004 |
Glycosidase inhibition by 1-glycosyl-4-phenyl triazoles.
Topics: Acetylene; Azides; Catalysis; Copper; Enzyme Inhibitors; Glycoside Hydrolases; Glycosides; Hydrolysis; Structure-Activity Relationship; Triazoles | 2005 |
Macrocycloadditions leading to conformationally restricted small molecules.
Topics: Alkynes; Azides; Catalysis; Copper; Cyclization; Macrocyclic Compounds; Molecular Conformation; Molecular Structure; Stereoisomerism; Triazoles | 2006 |
Tandem azidination- and hydroazidination-Huisgen [3 + 2] cycloadditions of ynamides. Synthesis of chiral amide-substituted triazoles.
Topics: Alkynes; Amides; Azides; Cyclization; Molecular Structure; Stereoisomerism; Triazoles | 2006 |
A convergent synthesis of new beta-turn mimics by click chemistry.
Topics: Alkynes; Azides; Catalysis; Cyclization; Molecular Conformation; Molecular Mimicry; Molecular Structure; Peptides, Cyclic; Triazoles | 2006 |
Rate of interfacial electron transfer through the 1,2,3-triazole linkage.
Topics: Alkynes; Azides; Catalysis; Copper; Cyclization; Electrodes; Electrons; Ferrous Compounds; Gold; Metallocenes; Metalloporphyrins; Molecular Structure; Oxidation-Reduction; Sulfhydryl Compounds; Surface Properties; Triazoles | 2006 |
Application of azide-alkyne cycloaddition 'click chemistry' for the synthesis of Grb2 SH2 domain-binding macrocycles.
Topics: Alkynes; Azides; Binding Sites; Copper; Cyclization; GRB2 Adaptor Protein; Ligands; Macrocyclic Compounds; Models, Molecular; Molecular Conformation; Protein Conformation; Sensitivity and Specificity; src Homology Domains; Stereoisomerism; Structure-Activity Relationship; Surface Plasmon Resonance; Time Factors; Triazoles | 2006 |
C-glycoside clustering on calix[4]arene, adamantane, and benzene scaffolds through 1,2,3-triazole linkers.
Topics: Adamantane; Alkynes; Azides; Benzene; Calixarenes; Combinatorial Chemistry Techniques; Cross-Linking Reagents; Glycosides; Monosaccharides; Phenols; Triazoles | 2006 |
In-situ synthesis of a tacrine-triazole-based inhibitor of acetylcholinesterase: configurational selection imposed by steric interactions.
Topics: Acetylcholinesterase; Acetylene; Azides; Binding Sites; Cholinesterase Inhibitors; Models, Molecular; Molecular Conformation; Quantum Theory; Tacrine; Triazoles | 2006 |
First synthesis of 1,2,3-triazolo-linked (1,6)-alpha-D-oligomannoses (triazolomannoses) by iterative Cu(I)-catalyzed alkyne-azide cycloaddition.
Topics: Alkynes; Azides; Carbohydrate Conformation; Catalysis; Glycosides; Mannose; Models, Molecular; Oligosaccharides; Triazoles | 2006 |
"Click to chelate": synthesis and installation of metal chelates into biomolecules in a single step.
Topics: Alanine; Alkynes; Azides; Chelating Agents; Isotope Labeling; Metals; Peptides; Triazoles | 2006 |
One-pot procedure for diazo transfer and azide-alkyne cycloaddition: triazole linkages from amines.
Topics: Alkynes; Amines; Azides; Azo Compounds; Glycosylation; Molecular Structure; Triazoles | 2007 |
Efficient conversion of aromatic amines into azides: a one-pot synthesis of triazole linkages.
Topics: Amines; Azides; Cross-Linking Reagents; Molecular Structure; Triazoles | 2007 |
Base dependence in copper-catalyzed Huisgen reactions: efficient formation of bistriazoles.
Topics: Alkynes; Azides; Catalysis; Copper; Crystallography, X-Ray; Models, Molecular; Molecular Structure; Stereoisomerism; Triazoles | 2007 |
Reactions of nitroso hetero-Diels-Alder cycloadducts with azides: stereoselective formation of triazolines and aziridines.
Topics: Alkenes; Amino Alcohols; Azides; Aziridines; Benzene; Molecular Structure; Nitroso Compounds; Photolysis; Stereoisomerism; Triazoles | 2007 |
Synthesis of bitriazolyl nucleosides and unexpectedly different reactivity of azidotriazole nucleoside isomers in the Huisgen reaction.
Topics: Ascorbic Acid; Azides; Catalysis; Copper; Isomerism; Microbial Sensitivity Tests; Models, Chemical; Nucleosides; Oxidation-Reduction; Triazoles | 2007 |
[3 + 2] Cycloaddition of acetylenes with azides to give 1,4-disubstituted 1,2,3-triazoles in a modular flow reactor.
Topics: Alkynes; Azides; Catalysis; Chemistry, Pharmaceutical; Copper; Equipment Design; Magnetic Resonance Spectroscopy; Models, Chemical; Peptides; Triazoles | 2007 |
Metal-free triazole formation as a tool for bioconjugation.
Topics: Alkynes; Azides; Coumarins; Cyclization; Magnetic Resonance Spectroscopy; Metals; Molecular Structure; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Triazoles | 2007 |
Solid-phase based synthesis of jasplakinolide analogs by intramolecular azide-alkyne cycloadditions.
Topics: Alkynes; Azides; Depsipeptides; Triazoles | 2007 |
Benzimidazole and related ligands for Cu-catalyzed azide-alkyne cycloaddition.
Topics: Alkynes; Azides; Benzimidazoles; Buffers; Calorimetry; Catalysis; Chemistry, Organic; Copper; Hydrogen-Ion Concentration; Kinetics; Ligands; Models, Chemical; Molecular Structure; Time Factors; Triazoles | 2007 |
Ligand-accelerated Cu-catalyzed azide-alkyne cycloaddition: a mechanistic report.
Topics: Alkynes; Amino Acid Motifs; Azides; Catalysis; Chemistry, Organic; Copper; Esters; Ions; Kinetics; Ligands; Models, Chemical; Models, Theoretical; Triazoles | 2007 |
Multi-mannosides based on a carbohydrate scaffold: synthesis, force field development, molecular dynamics studies, and binding affinities for lectin Con A.
Topics: Acetylation; Azides; Binding Sites; Carbohydrate Conformation; Carbohydrate Sequence; Concanavalin A; Lectins; Ligands; Mannosides; Models, Chemical; Molecular Sequence Data; Triazoles | 2007 |
Tandem epoxide or aziridine ring opening by azide/copper catalyzed [3+2] cycloaddition: efficient synthesis of 1,2,3-triazolo beta-hydroxy or beta-tosylamino functionality motif.
Topics: Azides; Aziridines; Catalysis; Copper; Cyclization; Epoxy Compounds; Molecular Structure; Stereoisomerism; Tosyl Compounds; Triazoles | 2007 |
A novel domino-click approach for the synthesis of sugar based unsymmetrical bis-1,2,3-triazoles.
Topics: Azides; Carbohydrates; Catalysis; Copper; Triazoles | 2008 |
Synthesis of an artificial oligonucleotide an efficient cycloaddition reaction.
Topics: Acetylene; Azides; Biochemistry; Oligonucleotides; Triazoles | 2007 |
Naphthoquinoidal [1,2,3]-triazole, a new structural moiety active against Trypanosoma cruzi.
Topics: Animals; Azides; Cations; Crystallography, X-Ray; Hydrogen Bonding; Models, Molecular; Molecular Structure; Naphthoquinones; Structure-Activity Relationship; Triazoles; Trypanocidal Agents; Trypanosoma cruzi | 2008 |
Alkyne-azide click chemistry mediated carbanucleosides synthesis.
Topics: Alkynes; Antiviral Agents; Azides; Cyclization; Microwaves; Molecular Structure; Nucleosides; Triazoles | 2007 |
Significant rate accelerated synthesis of glycosyl azides and glycosyl 1,2,3-triazole conjugates.
Topics: Azides; Glycosylation; Triazoles | 2008 |
Validation of the copper(i)-catalyzed azide-alkyne coupling in ionic liquids. Synthesis of a triazole-linked C-disaccharide as a case study.
Topics: Alkynes; Azides; Catalysis; Copper; Disaccharides; Triazoles | 2008 |
Preparation and reactions of sugar azides with alkynes: synthesis of sugar triazoles as antitubercular agents.
Topics: Alkynes; Antitubercular Agents; Azides; Carbohydrates; Cyclization; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Structure-Activity Relationship; Triazoles | 2008 |
Regioselective synthesis of 1-(2,6-dichloro-4-trifluoromethylphenyl)- 4-alkyl-1H-[1,2,3]-triazoles.
Topics: Azides; Catalysis; Copper; Crystallography, X-Ray; Molecular Conformation; Stereoisomerism; Triazoles | 2008 |
Benzyne click chemistry: synthesis of benzotriazoles from benzynes and azides.
Topics: Azides; Benzene Derivatives; Combinatorial Chemistry Techniques; Cyclization; Molecular Structure; Triazoles | 2008 |
'Click' cycloaddition catalysts: copper(I) and copper(II) tris(triazolylmethyl)amine complexes.
Topics: Alkynes; Azides; Catalysis; Copper; Crystallography, X-Ray; Cyclization; Ligands; Models, Molecular; Molecular Structure; Organometallic Compounds; Triazoles | 2008 |
Electrochemically protected copper(I)-catalyzed azide-alkyne cycloaddition.
Topics: Air; Alkynes; Azides; Catalysis; Copper; Electrochemistry; Ligands; Solubility; Triazoles | 2008 |
Mechanistic studies on the Cu-catalyzed three-component reactions of sulfonyl azides, 1-alkynes and amines, alcohols, or water: dichotomy via a common pathway.
Topics: Alcohols; Alkynes; Amines; Azides; Catalysis; Copper; Ethylenes; Imidoesters; Isomerism; Ketones; Kinetics; Models, Molecular; Molecular Structure; Sulfur Compounds; Temperature; Triazoles; Water | 2008 |
Ruthenium-catalyzed azide-alkyne cycloaddition: scope and mechanism.
Topics: Alkynes; Azides; Catalysis; Cyclization; Organometallic Compounds; Ruthenium; Triazoles | 2008 |
Synthesis of optically pure 2-azido-1-arylethanols with isolated enzymes and conversion to triazole-containing beta-blocker analogues employing click chemistry.
Topics: Acetophenones; Adrenergic beta-Antagonists; Alcohol Dehydrogenase; Alcohol Oxidoreductases; Alkynes; Azides; Candida; Ethanol; Saccharomyces cerevisiae; Stereoisomerism; Triazoles | 2008 |
Synthesis of 6'-branched locked nucleic acid by a radical TEMPO-scavanged stereoselective mercury cyclization.
Topics: Azides; Cyclic N-Oxides; Cyclization; Free Radical Scavengers; Mercury; Models, Chemical; Oligonucleotides; Stereoisomerism; Thymidine; Triazoles | 2008 |
Reversible and competitive cinnamoyl triazole inhibitors of tissue transglutaminase.
Topics: Alkynes; Animals; Azides; Catalysis; Cinnamates; Enzyme Inhibitors; GTP-Binding Proteins; Guinea Pigs; Protein Glutamine gamma Glutamyltransferase 2; Transglutaminases; Triazoles | 2008 |
Nucleosides and oligonucleotides containing 1,2,3-triazole residues with nucleobase tethers: synthesis via the azide-alkyne 'click' reaction.
Topics: Alkynes; Azides; Combinatorial Chemistry Techniques; DNA; Fluorescent Dyes; Models, Chemical; Nucleic Acid Conformation; Nucleosides; Oligonucleotides; Organophosphorus Compounds; Triazoles | 2008 |
A copper(I)-catalyzed 1,2,3-triazole azide-alkyne click compound is a potent inhibitor of a multidrug-resistant HIV-1 protease variant.
Topics: Alkenes; Azides; Catalysis; Cell Line; Copper; Crystallography, X-Ray; Drug Resistance, Multiple, Viral; HIV Protease; HIV Protease Inhibitors; Isoenzymes; Models, Molecular; Molecular Structure; Protein Binding; Triazoles; Virus Replication | 2008 |
A [(NHC)CuCl] complex as a latent Click catalyst.
Topics: Acetylene; Azides; Catalysis; Copper; Crystallography, X-Ray; Cyclization; Heterocyclic Compounds; Imidazolidines; Methane; Models, Molecular; Molecular Structure; Organometallic Compounds; Stereoisomerism; Triazoles | 2008 |
Histone deacetylase inhibitors through click chemistry.
Topics: Alkynes; Azides; Cell Line, Tumor; Cell Proliferation; Cyclization; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Molecular Structure; Stereoisomerism; Triazoles | 2008 |
Synthesis of spiroacetal-triazoles as privileged natural product-like scaffolds using "click chemistry".
Topics: Azides; Biological Products; Ethers; Spiro Compounds; Triazoles | 2008 |
Microwave-assisted intramolecular Huisgen cycloaddition of azido alkynes derived from alpha-amino acids.
Topics: Alkynes; Amides; Amino Acids; Azides; Cyclization; Microwaves; Stereoisomerism; Triazoles | 2009 |
"Flash" solvent-free synthesis of triazoles using a supported catalyst.
Topics: Alkynes; Azides; Catalysis; Combinatorial Chemistry Techniques; Copper; Molecular Structure; Solvents; Triazoles | 2009 |
Cu(II)-hydrotalcite as an efficient heterogeneous catalyst for Huisgen [3+2] cycloaddition.
Topics: Alkynes; Aluminum Hydroxide; Azides; Catalysis; Combinatorial Chemistry Techniques; Copper; Cyclization; Magnesium Hydroxide; Molecular Structure; Triazoles | 2009 |
Benzyne click chemistry with in situ generated aromatic azides.
Topics: Alkynes; Azides; Benzene Derivatives; Combinatorial Chemistry Techniques; Cyclization; Molecular Structure; Triazoles | 2009 |
Chitinase inhibitors: extraction of the active framework from natural argifin and use of in situ click chemistry.
Topics: Azides; Chitinases; Cyclization; Drug Evaluation, Preclinical; Enzyme Inhibitors; Mass Spectrometry; Peptides, Cyclic; Reverse Transcriptase Polymerase Chain Reaction; Spectrophotometry, Infrared; Triazoles | 2009 |
Expedient and rapid synthesis of 1,2,3-triazolo[5,1-c]morpholines through palladium-copper catalysis.
Topics: Azides; Catalysis; Copper; Kinetics; Morpholines; Palladium; Stereoisomerism; Substrate Specificity; Triazoles | 2009 |
Facile entry into triazole fused heterocycles via sulfamidate derived azido-alkynes.
Topics: Alkynes; Azides; Cyclization; Molecular Conformation; Stereoisomerism; Sulfonic Acids; Triazoles | 2009 |
Copper(I)-catalyzed cycloaddition of organic azides and 1-iodoalkynes.
Topics: Azides; Catalysis; Copper; Iodine; Triazoles | 2009 |
Apparent copper(II)-accelerated azide-alkyne cycloaddition.
Topics: Alkynes; Azides; Catalysis; Combinatorial Chemistry Techniques; Copper; Cyclization; Molecular Structure; Oxidation-Reduction; Propanols; Triazoles | 2009 |
Copper-catalyzed azide-alkyne cycloaddition: regioselective synthesis of 1,4,5-trisubstituted 1,2,3-triazoles.
Topics: Alkynes; Azides; Catalysis; Copper; Iodine; Stereoisomerism; Triazoles | 2010 |
Copper(II)/copper(I)-catalyzed aza-Michael addition/click reaction of in situ generated alpha-azidohydrazones: synthesis of novel pyrazolone-triazole framework.
Topics: Alkynes; Azides; Catalysis; Copper; Cyclization; Hydrazones; Molecular Structure; Pyrazolones; Triazoles | 2010 |
Copper-free cycloaddition of azide and alkyne in crystalline state facilitated by arene-perfluoroarene interactions.
Topics: Alkynes; Azides; Crystallization; Crystallography, X-Ray; Cyclization; Models, Molecular; Molecular Structure; Triazoles | 2010 |
One pot 'click' reactions: tandem enantioselective biocatalytic epoxide ring opening and [3+2] azide alkyne cycloaddition.
Topics: Alkynes; Azides; Biocatalysis; Epoxy Compounds; Hydrolases; Stereoisomerism; Triazoles | 2010 |
Direct synthesis of 1,4-disubstituted-5-alumino-1,2,3-triazoles: copper-catalyzed cycloaddition of organic azides and mixed aluminum acetylides.
Topics: Aluminum; Azides; Catalysis; Copper; Molecular Structure; Solvents; Triazoles | 2010 |
D-ring substituted 1,2,3-triazolyl 20-keto pregnenanes as potential anticancer agents: Synthesis and biological evaluation.
Topics: Acetylene; Antineoplastic Agents; Azides; Catalysis; Cell Line, Tumor; Copper; Humans; Inhibitory Concentration 50; Pregnenes; Stereoisomerism; Substrate Specificity; Triazoles | 2010 |
Azides derived from colchicine and their use in library synthesis: A practical entry to new bioactive derivatives of an old natural drug.
Topics: Antineoplastic Agents; Azides; Colchicine; Crystallography, X-Ray; HeLa Cells; Humans; Molecular Conformation; Triazoles; Tubulin Modulators | 2010 |
'Click chemistry' synthesis of a library of 1,2,3-triazole-substituted galactose derivatives and their evaluation against Trypanosoma cruzi and its cell surface trans-sialidase.
Topics: Animals; Azides; Cell Line; Cell Survival; Chromatography, Thin Layer; Fluorometry; Galactose; Indicators and Reagents; Magnetic Resonance Spectroscopy; Membrane Proteins; Mice; Mice, Inbred C57BL; N-Acetylneuraminic Acid; Neuraminidase; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet; Spleen; Structure-Activity Relationship; Triazoles; Trypanocidal Agents; Trypanosoma cruzi | 2010 |
Fused tetrazoles as azide surrogates in click reaction: efficient synthesis of N-heterocycle-substituted 1,2,3-triazoles.
Topics: Azides; Catalysis; Heterocyclic Compounds; Tetrazoles; Triazoles | 2010 |
Synthesis of DOTA-conjugated multimeric [Tyr3]octreotide peptides via a combination of Cu(I)-catalyzed "click" cycloaddition and thio acid/sulfonyl azide "sulfo-click" amidation and their in vivo evaluation.
Topics: Alkynes; Animals; Azides; Binding, Competitive; Catalysis; Cell Line, Tumor; Copper; Cyclization; Dendrimers; Heterocyclic Compounds, 1-Ring; Indium Radioisotopes; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Octreotide; Polymers; Radiopharmaceuticals; Rats; Receptors, Somatostatin; Structure-Activity Relationship; Sulfonamides; Tissue Distribution; Transplantation, Heterologous; Triazoles | 2010 |
Interaction kinetics of oximes with native, phosphylated and aged human acetylcholinesterase.
Topics: Acetylcholinesterase; Alkynes; Animals; Azides; Catalysis; Catalytic Domain; Cell Line; Cholinesterase Reactivators; Copper; Enzyme Activation; Humans; Kinetics; Mice; Models, Molecular; Organophosphates; Oximes; Phosphorylation; Protein Binding; Spectrometry, Fluorescence; Triazoles; Tryptophan | 2010 |
Synthesis of alpha- and beta-D-glucopyranosyl triazoles by CuAAC 'click chemistry': reactant tolerance, reaction rate, product structure and glucosidase inhibitory properties.
Topics: Alkynes; Azides; Catalysis; Copper; Crystallography, X-Ray; Enzyme Inhibitors; Glucosidases; Kinetics; Prunus; Stereoisomerism; Triazoles | 2010 |
Clickable peptide nucleic acids (cPNA) with tunable affinity.
Topics: Alkynes; Azides; Cyclization; DNA; Nucleic Acid Hybridization; Peptide Nucleic Acids; Triazoles | 2010 |
Regioselective [3+2] cycloaddition of chalcones with a sugar azide: easy access to 1-(5-deoxy-D-xylofuranos-5-yl)-4,5-disubstituted-1H-1,2,3-triazoles.
Topics: Azides; Chalcones; Cyclization; Molecular Structure; Stereoisomerism; Triazoles; Xylose | 2010 |
Fluorogenic "click" reaction for labeling and detection of DNA in proliferating cells.
Topics: Animals; Azides; Cell Proliferation; Coumarins; Deoxyuridine; DNA; Fluorescent Dyes; HeLa Cells; Humans; Mice; NIH 3T3 Cells; Triazoles | 2010 |
An unexpected example of protein-templated click chemistry.
Topics: Alkynes; Azides; Catalysis; Click Chemistry; Copper; Fluorometry; Histone Deacetylase Inhibitors; Histone Deacetylases; Triazoles | 2010 |
Click-chemistry-derived triazole ligands of arginine-glycine-aspartate (RGD) integrins with a broad capacity to inhibit adhesion of melanoma cells and both in vitro and in vivo angiogenesis.
Topics: Alkynes; Angiogenesis Inhibitors; Animals; Azides; Cell Adhesion; Cell Line, Tumor; Drug Screening Assays, Antitumor; Endothelial Cells; Extracellular Matrix Proteins; Humans; Integrin alphaVbeta3; Ligands; Melanoma; Mice; Mice, Inbred C57BL; Models, Molecular; Molecular Mimicry; Neovascularization, Pathologic; Oligopeptides; Phenylpropionates; Protein Binding; Radioligand Assay; Receptors, Vitronectin; Stereoisomerism; Structure-Activity Relationship; Triazoles | 2010 |
Benzotriazol-1-yl-sulfonyl azide for diazotransfer and preparation of azidoacylbenzotriazoles.
Topics: Azides; Molecular Structure; Stereoisomerism; Triazoles | 2010 |
Structure-properties relationship of biosourced stereocontrolled polytriazoles from click chemistry step growth polymerization of diazide and dialkyne dianhydrohexitols.
Topics: Alkynes; Azides; Catalysis; Chemical Phenomena; Click Chemistry; Copper; Cyclization; Molecular Structure; Polymerization; Polymers; Stereoisomerism; Structure-Activity Relationship; Sugar Alcohols; Triazoles | 2010 |
Carboxylic acid-promoted copper(I)-catalyzed azide-alkyne cycloaddition.
Topics: Alkynes; Azides; Carboxylic Acids; Catalysis; Copper; Cyclization; Molecular Structure; Stereoisomerism; Triazoles | 2010 |
One-pot three-step synthesis of 1,2,3-triazoles by copper-catalyzed cycloaddition of azides with alkynes formed by a Sonogashira cross-coupling and desilylation.
Topics: Alkynes; Azides; Catalysis; Copper; Cyclization; Microwaves; Molecular Structure; Silanes; Triazoles | 2010 |
C-H bond functionalization in the synthesis of fused 1,2,3-triazoles.
Topics: Alkynes; Azides; Catalysis; Combinatorial Chemistry Techniques; Copper; Cyclization; Heterocyclic Compounds, 4 or More Rings; Molecular Structure; Palladium; Triazoles | 2010 |
Inhibition of human neuraminidase 3 (NEU3) by C9-triazole derivatives of 2,3-didehydro-N-acetyl-neuraminic acid.
Topics: Alkynes; Azides; Binding Sites; Catalysis; Computer Simulation; Copper; Humans; N-Acetylneuraminic Acid; Neuraminidase; Structure-Activity Relationship; Triazoles | 2010 |
Efficient access to new chemical space through flow--construction of druglike macrocycles through copper-surface-catalyzed azide-alkyne cycloaddition reactions.
Topics: Alkynes; Azides; Catalysis; Click Chemistry; Combinatorial Chemistry Techniques; Copper; Cyclization; Hot Temperature; Macrocyclic Compounds; Models, Molecular; Molecular Structure; Triazoles | 2010 |
Design, synthesis and in vitro antimalarial evaluation of triazole-linked chalcone and dienone hybrid compounds.
Topics: Alkynes; Aminoquinolines; Animals; Antimalarials; Azides; Catalysis; Chalcone; Chalcones; Copper; Drug Design; Hemin; Nucleosides; Plasmodium falciparum; Quinolines; Structure-Activity Relationship; Triazoles | 2010 |
Traceless azido linker for the solid-phase synthesis of NH-1,2,3-triazoles via Cu-catalyzed azide-alkyne cycloaddition reactions.
Topics: Alkynes; Azides; Catalysis; Copper; Cyclization; Molecular Structure; Triazoles | 2010 |
Straightforward synthesis of triazoloacyclonucleotide phosphonates as potential HCV inhibitors.
Topics: Alkynes; Antiviral Agents; Azides; Catalysis; Cell Line, Tumor; Copper; Hepacivirus; Humans; Nucleotides; Organophosphonates; Structure-Activity Relationship; Triazoles; Virus Replication | 2010 |
Biocompatible copper(I) catalysts for in vivo imaging of glycans.
Topics: Alkynes; Animals; Azides; Biocompatible Materials; Blastula; Catalysis; Cell Line; Cell Survival; Click Chemistry; Copper; Embryonic Development; Fucose; Humans; Microinjections; Molecular Imaging; Polysaccharides; Time Factors; Triazoles; Zebrafish | 2010 |
Synthesis of unsymmetrical 1,1'-disubstituted bis(1,2,3-triazole)s using monosilylbutadiynes.
Topics: Alkynes; Azides; Catalysis; Combinatorial Chemistry Techniques; Molecular Structure; Triazoles | 2011 |
Synthesis and triplex-forming ability of oligonucleotides bearing 1-substituted 1H-1,2,3-triazole nucleobases.
Topics: Azides; Base Pairing; DNA; Drug Design; Heterocyclic Compounds; Oligonucleotides; Phenylurea Compounds; Triazoles | 2011 |
Copper-catalyzed azide-alkyne cycloaddition in the synthesis of polydiacetylene: "click glycoliposome" as biosensors for the specific detection of lectins.
Topics: Alkynes; Azides; Biosensing Techniques; Catalysis; Click Chemistry; Colorimetry; Concanavalin A; Copper; Glycolipids; Liposomes; Molecular Structure; Polyacetylene Polymer; Polymers; Polyynes; Triazoles | 2011 |
Anaerobic conditions to reduce oxidation of proteins and to accelerate the copper-catalyzed "Click" reaction with a water-soluble bis(triazole) ligand.
Topics: Alkynes; Animals; Azides; Catalysis; Cattle; Click Chemistry; Copper; Ligands; Oxidation-Reduction; Serum Albumin, Bovine; Triazoles; Water | 2011 |
A photolabile linker for the solid-phase synthesis of 4-substituted NH-1,2,3-triazoles.
Topics: Alkynes; Azides; Catalysis; Copper; Photolysis; Triazoles; Ultraviolet Rays | 2011 |
Facile synthesis of 4-vinyl- and 4-fluorovinyl-1,2,3-triazoles via bifunctional "click-olefination" reagents.
Topics: Alkynes; Azides; Catalysis; Click Chemistry; Copper; Halogenation; Molecular Structure; Sulfones; Triazoles | 2011 |
Triazole ligands reveal distinct molecular features that induce histamine H4 receptor affinity and subtly govern H4/H3 subtype selectivity.
Topics: Alkynes; Azides; Click Chemistry; HEK293 Cells; Humans; Imidazoles; Ligands; Models, Molecular; Radioligand Assay; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H3; Receptors, Histamine H4; Structure-Activity Relationship; Triazoles | 2011 |
A comparison of triazole-forming bioconjugation techniques for constructing comb-shaped peptide-polymer bioconjugates.
Topics: Alkynes; Azides; Catalysis; Click Chemistry; Copper; Cycloaddition Reaction; Gramicidin; Methacrylates; Molecular Structure; Polymethacrylic Acids; Triazoles | 2011 |
Synthesis of variously coupled conjugates of D-glucose, 1,3,4-oxadiazole, and 1,2,3-triazole for inhibition of glycogen phosphorylase.
Topics: Alkynes; Animals; Azides; Catalysis; Diabetes Mellitus, Type 2; Enzyme Inhibitors; Glucose; Glycoconjugates; Glycogen Phosphorylase, Muscle Form; Humans; Kinetics; Oxadiazoles; Phosphorylase b; Propionates; Rabbits; Triazoles | 2011 |
Promotion of sleep by suvorexant-a novel dual orexin receptor antagonist.
Topics: Animals; Area Under Curve; Azepines; Azides; CHO Cells; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Electrocardiography; Electromyography; Humans; Macaca mulatta; Motor Activity; Octreotide; Orexin Receptors; Protein Binding; Rats; Reaction Time; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Sleep; Transfection; Triazoles | 2011 |
A combined experimental and theoretical study of the thermal cycloaddition of aryl azides with activated alkenes.
Topics: Alkenes; Anti-Bacterial Agents; Antifungal Agents; Antineoplastic Agents; Azides; Cell Line, Tumor; Cyclization; Drug Screening Assays, Antitumor; Humans; Microbial Sensitivity Tests; Microwaves; Molecular Structure; Quantum Theory; Stereoisomerism; Structure-Activity Relationship; Temperature; Triazoles | 2011 |
Stereo- and regioselective azide/alkyne cycloadditions in carbonic anhydrase II via tethering, monitored by crystallography and mass spectrometry.
Topics: Alkynes; Azides; Binding Sites; Carbonic Anhydrase II; Catalysis; Crystallography; Cyclization; Mass Spectrometry; Sulfonamides; Triazoles; Zinc | 2011 |
Viability of 4,5-dihydro-1,2,3,4-oxatriazoles reinvestigated.
Topics: Azides; Catalysis; Magnetic Resonance Spectroscopy; Molecular Structure; Triazoles | 2011 |
1,3-Dipolar cycloaddition of sugar azides with benzyne: a novel synthesis of 1,2,3-benzotriazolyl glycoconjugates.
Topics: Azides; Benzene Derivatives; Glycoconjugates; Triazoles | 2011 |
CuAAC macrocyclization: high intramolecular selectivity through the use of copper-tris(triazole) ligand complexes.
Topics: Alkynes; Azides; Copper; Cyclization; Ligands; Molecular Structure; Triazoles | 2011 |
Synthesis of novel molecular probes inspired by harringtonolide.
Topics: Antineoplastic Agents, Phytogenic; Azides; Catalysis; Chemistry, Pharmaceutical; Click Chemistry; Copper; Cyclopentanes; Drug Discovery; Harringtonines; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Probes; Neoplasms; Plants, Medicinal; Small Molecule Libraries; Stereoisomerism; Taxaceae; Triazoles | 2011 |
Unprecedented Cu-catalyzed coupling of internal 1,3-diynes with azides: one-pot tandem cyclizations involving 1,3-dipolar cycloaddition and carbocyclization furnishing naphthotriazoles.
Topics: Azides; Catalysis; Combinatorial Chemistry Techniques; Copper; Cyclization; Diynes; Molecular Structure; Triazoles | 2011 |
Synthesis and anti-HIV evaluation of 3'-triazolo nucleosides.
Topics: Animals; Anti-HIV Agents; Azides; Cell Line; HIV Reverse Transcriptase; HIV-1; Humans; Nucleosides; Structure-Activity Relationship; Triazoles | 2011 |
Rapid preparation of triazolyl substituted NH-heterocyclic kinase inhibitors via one-pot Sonogashira coupling-TMS-deprotection-CuAAC sequence.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Alkynes; Azides; Catalysis; Copper; Crystallography, X-Ray; Cyclization; Heterocyclic Compounds; Models, Molecular; Molecular Structure; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Stereoisomerism; Structure-Activity Relationship; Triazoles; Trimethylsilyl Compounds | 2011 |
Novel application of α-azido aldehydes in multicomponent reactions: synthesis of triazolo-fused dihydrooxazinones via a Passerini reaction-dipolar cycloaddition strategy.
Topics: Aldehydes; Azides; Chemistry Techniques, Synthetic; Cyclization; Molecular Structure; Oxazines; Stereoisomerism; Triazoles | 2011 |
Synthesis of novel alkyltriazole tagged pyrido[2,3-d]pyrimidine derivatives and their anticancer activity.
Topics: Alkylation; Antineoplastic Agents; Azides; Cell Line, Tumor; Cell Survival; Colorectal Neoplasms; Cyclization; Drug Screening Assays, Antitumor; Humans; Inhibitory Concentration 50; Leukemia, Monocytic, Acute; Lymphoma; Pyrimidines; Structure-Activity Relationship; Triazoles | 2011 |
Strain-promoted alkyne-azide cycloadditions (SPAAC) reveal new features of glycoconjugate biosynthesis.
Topics: Alkynes; Animals; Azides; CHO Cells; Click Chemistry; Cricetinae; Cricetulus; Glycoconjugates; Glycoproteins; Glycosylation; Golgi Apparatus; Humans; Jurkat Cells; Lectins; Molecular Probe Techniques; N-Acetylneuraminic Acid; Polysaccharides; Protein Transport; Spectrometry, Fluorescence; Staining and Labeling; Triazoles | 2011 |
Parallel synthesis of novel antitumor agents: 1,2,3-triazoles bearing biologically active sulfonamide moiety and their 3D-QSAR.
Topics: Alkynes; Antineoplastic Agents; Azides; Cell Line, Tumor; Chemistry Techniques, Synthetic; Humans; Inhibitory Concentration 50; Models, Molecular; Molecular Conformation; Quantitative Structure-Activity Relationship; Sulfonamides; Triazoles | 2011 |
Copper(I)-catalyzed cycloaddition of silver acetylides and azides: incorporation of volatile acetylenes into the triazole core.
Topics: Alkynes; Azides; Catalysis; Copper; Cyclization; Silver; Triazoles | 2011 |
Three-component synthesis of neoglycopeptides using a Cu(II)-triggered aminolysis of peptide hydrazide resin and an azide-alkyne cycloaddition sequence.
Topics: Alkynes; Amines; Azides; Catalysis; Copper; Glycopeptides; Molecular Structure; Oxidation-Reduction; Peptides; Triazoles | 2011 |
Synthesis and reactivity of sulfamoyl azides and 1-sulfamoyl-1,2,3-triazoles.
Topics: Azides; Molecular Structure; Stereoisomerism; Triazoles | 2011 |
Synthesis of 4β-triazole-podophyllotoxin derivatives by azide-alkyne cycloaddition and biological evaluation as potential antitumor agents.
Topics: Antineoplastic Agents; Azides; Cell Line, Tumor; Cyclization; Drug Screening Assays, Antitumor; Humans; Magnetic Resonance Spectroscopy; Models, Molecular; Podophyllotoxin; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Infrared; Triazoles | 2011 |
Amphiphilic 1-deoxynojirimycin derivatives through click strategies for chemical chaperoning in N370S Gaucher cells.
Topics: 1-Deoxynojirimycin; Alkynes; Animals; Azides; Cattle; Click Chemistry; Enzyme Inhibitors; Gaucher Disease; Glucosylceramidase; Hydrophobic and Hydrophilic Interactions; Triazoles | 2011 |
Metal-free 1,5-regioselective azide-alkyne [3+2]-cycloaddition.
Topics: Alkynes; Azides; Crystallography, X-Ray; Cyclization; Metals; Models, Molecular; Molecular Structure; Quantum Theory; Stereoisomerism; Triazoles | 2011 |
Solid-phase synthesis of smac peptidomimetics incorporating triazoloprolines and biarylalanines.
Topics: Alanine; Alkynes; Azides; Catalysis; Copper; Hydrocarbons, Aromatic; Inhibitor of Apoptosis Proteins; Models, Chemical; Oligopeptides; Palladium; Peptidomimetics; Proline; Solid-Phase Synthesis Techniques; Triazoles | 2011 |
Ligand-assisted, copper(II) acetate-accelerated azide-alkyne cycloaddition.
Topics: Alkynes; Azides; Cyclization; Ligands; Molecular Structure; Organometallic Compounds; Stereoisomerism; Triazoles | 2011 |
Quick and highly efficient copper-catalyzed cycloaddition of organic azides with terminal alkynes.
Topics: Alkynes; Azides; Catalysis; Copper; Cyclization; Molecular Structure; Organometallic Compounds; Stereoisomerism; Triazoles | 2012 |
Efficient synthesis and in vitro antitubercular activity of 1,2,3-triazoles as inhibitors of Mycobacterium tuberculosis.
Topics: Alkynes; Antitubercular Agents; Azides; Fatty Acids, Unsaturated; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Triazoles | 2011 |
Crosslinked cellulose developed by CuAAC, a route to new materials.
Topics: Alkynes; Ascorbic Acid; Azides; Catalysis; Cellulose; Click Chemistry; Copper Sulfate; Magnetic Resonance Spectroscopy; Microscopy, Electron, Scanning; Photoelectron Spectroscopy; Triazoles; Water | 2012 |
Regioselective synthesis and structural elucidation of 1,4-disubstituted 1,2,3-triazole derivatives using 1D and 2D NMR spectral techniques.
Topics: Azides; Benzaldehydes; Chemistry Techniques, Synthetic; Chromatography, Gel; Cyclization; Mass Spectrometry; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Spectrophotometry, Infrared; Stereoisomerism; Triazoles | 2011 |
Synthesis of a biologically active triazole-containing analogue of cystatin A through successive peptidomimetic alkyne-azide ligations.
Topics: Alkynes; Amino Acid Sequence; Azides; Cathepsins; Cell Line, Tumor; Click Chemistry; Cyclization; Cystatin A; Humans; Molecular Sequence Data; Neoplasm Invasiveness; Peptidomimetics; Triazoles | 2012 |
Design, synthesis and the effect of 1,2,3-triazole sialylmimetic neoglycoconjugates on Trypanosoma cruzi and its cell surface trans-sialidase.
Topics: Alkynes; Antiparasitic Agents; Azides; Catalysis; Click Chemistry; Copper; Drug Design; Enzyme Inhibitors; Glycoconjugates; Glycoproteins; Neuraminidase; Sialic Acids; Triazoles; Trypanosoma cruzi | 2012 |
Design of triazole-stapled BCL9 α-helical peptides to target the β-catenin/B-cell CLL/lymphoma 9 (BCL9) protein-protein interaction.
Topics: Alkynes; Azides; beta Catenin; Cell Line, Tumor; Circular Dichroism; Crystallography, X-Ray; Culture Media; Humans; Models, Molecular; Neoplasm Proteins; Oligopeptides; Peptide Hydrolases; Protein Interaction Maps; Protein Structure, Secondary; Solid-Phase Synthesis Techniques; Stereoisomerism; Structure-Activity Relationship; Transcription Factors; Triazoles | 2012 |
Effective and reversible DNA condensation induced by bifunctional molecules containing macrocyclic polyamines and naphthyl moieties.
Topics: Alkynes; Azides; Catalysis; Cell Line, Tumor; Copper; DNA; Humans; Macrocyclic Compounds; Microscopy, Atomic Force; Naphthols; Osmolar Concentration; Polyamines; Triazoles | 2012 |
Enantioselective synthesis of C-linked spiroacetal-triazoles as privileged natural product-like scaffolds.
Topics: Alkynes; Azides; Biological Products; Carbon; Catalysis; Chemistry Techniques, Synthetic; Copper; Spiro Compounds; Stereoisomerism; Substrate Specificity; Triazoles | 2012 |
Efficient synthesis and cell-based silencing activity of siRNAS that contain triazole backbone linkages.
Topics: Azides; Base Sequence; Click Chemistry; Gene Silencing; Luciferases; Molecular Sequence Data; Molecular Structure; Real-Time Polymerase Chain Reaction; RNA, Small Interfering; Triazoles; Trityl Compounds | 2012 |
Application of a sequential multicomponent assembly process/huisgen cycloaddition strategy to the preparation of libraries of 1,2,3-triazole-fused 1,4-benzodiazepines.
Topics: Alkynes; Azides; Benzodiazepines; Catalysis; Cyclization; Small Molecule Libraries; Triazoles | 2012 |
α-Azido ketones. Part 7: synthesis of 1,4-disubstituted triazoles by the "click" reaction of various terminal acetylenes with phenacyl azides or α-azidobenzo(hetera)cyclanones.
Topics: Alkynes; Azides; Benzene; Chromones; Click Chemistry; Cyclization; Ketones; Triazoles | 2012 |
Synthesis and evaluation of triazole-linked poly(ε-caprolactone)-graft-poly(2-methyl-2-oxazoline) copolymers as potential drug carriers.
Topics: Alkynes; Azides; Catalysis; Click Chemistry; Copper; Drug Carriers; Micelles; Polyamines; Polyesters; Polymers; Triazoles | 2012 |
Stereoselective synthesis of bio-hybrid amphiphiles of coumarin derivatives by Ugi-Mannich triazole randomization using copper catalyzed alkyne azide click chemistry.
Topics: Alkynes; Azides; Catalysis; Click Chemistry; Copper Sulfate; Coumarins; Molecular Structure; Peptides; Stereoisomerism; Surface-Active Agents; Triazoles | 2012 |
A chemo-mechanical tweezer for single-molecular characterization of soft materials.
Topics: Azides; Macromolecular Substances; Microscopy, Atomic Force; Polymers; Triazoles | 2012 |
Copper(I) acetate-catalyzed azide-alkyne cycloaddition for highly efficient preparation of 1-(pyridin-2-yl)-1,2,3-triazoles.
Topics: Alkynes; Azides; Catalysis; Cyclization; Molecular Structure; Organometallic Compounds; Pyridines; Triazoles | 2012 |
Discovery of inhibitors of Leishmania β-1,2-mannosyltransferases using a click-chemistry-derived guanosine monophosphate library.
Topics: Animals; Antiparasitic Agents; Azides; Cell-Free System; Chemistry, Pharmaceutical; Combinatorial Chemistry Techniques; Female; Gene Library; Guanosine Diphosphate; Guanosine Diphosphate Mannose; Humans; Inhibitory Concentration 50; Kinetics; Leishmania; Ligands; Mannosyltransferases; Models, Chemical; Polymers; Psychodidae; Triazoles | 2012 |
Fused ring aziridines as a facile entry into triazole fused tricyclic and bicyclic heterocycles.
Topics: Alkynes; Azides; Aziridines; Cyclization; Humans; Molecular Structure; Oxazolidinones; RNA; Triazoles | 2012 |
Task-specific nitrite and azide ionic liquids for the efficient one-pot synthesis of 1,2,3-triazoles from the aniline derivatives.
Topics: Aniline Compounds; Azides; Ionic Liquids; Magnetic Resonance Spectroscopy; Molecular Structure; Nitrites; Spectroscopy, Fourier Transform Infrared; Triazoles | 2012 |
Traceless tosylhydrazone-based triazole formation: a metal-free alternative to strain-promoted azide-alkyne cycloaddition.
Topics: Alkynes; Azides; Benzenesulfonates; Cyclization; Hydrazones; Molecular Structure; Triazoles | 2012 |
Synthesis of 1,2,3-triazole derivatives and in vitro antifungal evaluation on Candida strains.
Topics: Animals; Antifungal Agents; Azides; Candida; Click Chemistry; Drug Design; Male; Miconazole; Microbial Sensitivity Tests; Propanols; Rats; Rats, Wistar; Structure-Activity Relationship; Triazoles | 2012 |
RuH2(CO)(PPh3)3 catalyzed selective formation of 1,4-disubstituted triazoles from cycloaddition of alkynes and organic azides.
Topics: Alkynes; Azides; Catalysis; Cyclization; Molecular Structure; Organometallic Compounds; Ruthenium; Triazoles | 2012 |
One-pot, two-step cascade synthesis of quinazolinotriazolobenzodiazepines.
Topics: Alkynes; Azides; Benzodiazepines; Catalysis; Cycloaddition Reaction; Molecular Structure; Triazoles | 2012 |
Synthesis of 5-iodo-1,4-disubstituted-1,2,3-triazoles mediated by in situ generated copper(I) catalyst and electrophilic triiodide ion.
Topics: Alkynes; Azides; Catalysis; Copper; Cyclization; Iodides; Ions; Molecular Structure; Triazoles | 2012 |
Synthesis of selective agonists for the α7 nicotinic acetylcholine receptor with in situ click-chemistry on acetylcholine-binding protein templates.
Topics: Alkynes; alpha7 Nicotinic Acetylcholine Receptor; Animals; Aplysia; Azides; Carrier Proteins; Cell Line; Click Chemistry; Humans; Lymnaea; Mice; Mutation; Nicotinic Agonists; Nicotinic Antagonists; Radioligand Assay; Receptors, Nicotinic; Stereoisomerism; Structure-Activity Relationship; Triazoles; Tropanes | 2012 |
Azide-alkyne cycloaddition en route to novel 1H-1,2,3-triazole tethered isatin conjugates with in vitro cytotoxic evaluation.
Topics: Alkynes; Antineoplastic Agents; Azides; Cell Line, Tumor; Cycloaddition Reaction; Humans; Isatin; Triazoles | 2012 |
Ring expansion of alkynyl cyclopropanes to highly substituted cyclobutenes via a N-sulfonyl-1,2,3-triazole intermediate.
Topics: Alkynes; Azides; Catalysis; Copper; Cycloaddition Reaction; Cyclopropanes; Methane; Silver; Triazoles | 2013 |
Synthesis of multivalent neoglyconjugates of MUC1 by the conjugation of carbohydrate-centered, triazole-linked glycoclusters to MUC1 peptides using click chemistry.
Topics: Alkynes; Azides; Carbohydrates; Catalysis; Click Chemistry; Copper; Cyclization; Glycoconjugates; Molecular Conformation; Mucin-1; Peptides; Triazoles | 2012 |
Copper catalysed azide-alkyne cycloaddition (CuAAC) in liquid ammonia.
Topics: Alkynes; Ammonia; Azides; Catalysis; Copper; Cyclization; Molecular Structure; Organometallic Compounds; Triazoles | 2012 |
Design and synthesis of new chacones substituted with azide/triazole groups and analysis of their cytotoxicity towards HeLa cells.
Topics: Alkylation; Azides; Catalysis; Cell Death; Cell Line, Tumor; Cell Survival; Chalcones; Cycloaddition Reaction; Drug Design; Female; HeLa Cells; Humans; Inhibitory Concentration 50; Molecular Structure; Triazoles | 2012 |
Synthesis of deuterated 1,2,3-triazoles.
Topics: Alkynes; Azides; Catalysis; Copper; Cyclization; Molecular Structure; Triazoles | 2012 |
Copper-catalyzed Huisgen and oxidative Huisgen coupling reactions controlled by polysiloxane-supported amines (AFPs) for the divergent synthesis of triazoles and bistriazoles.
Topics: Alkynes; Amines; Azides; Catalysis; Click Chemistry; Copper; Cycloaddition Reaction; Oxidative Coupling; Siloxanes; Triazoles | 2012 |
A ratiometric fluorescent on-off Zn2+ chemosensor based on a tripropargylamine pyrene azide click adduct.
Topics: Azides; Catalysis; Click Chemistry; Copper; Fluorescence; Fluorescent Dyes; Molecular Structure; Organometallic Compounds; Pyrenes; Triazoles; Zinc | 2012 |
Synthesis of amino, azido, nitro, and nitrogen-rich azole-substituted derivatives of 1H-benzotriazole for high-energy materials applications.
Topics: Amines; Azides; Electric Power Supplies; Models, Molecular; Molecular Structure; Nitrogen; Triazoles | 2012 |
Iron-facilitated oxidative dehydrogenative C-O bond formation by propargylic C sp 3-H functionalization.
Topics: Azides; Carbon; Carboxylic Acids; Catalysis; Hydrogen; Iron; Oxidation-Reduction; Oxygen; Triazoles | 2012 |
A fluorogenic probe for the catalyst-free detection of azide-tagged molecules.
Topics: Azides; Cyclization; Fluorescent Dyes; Molecular Structure; Quantum Theory; Triazoles | 2012 |
Azide-alkyne cycloaddition en route towards 1H-1,2,3-triazole-tethered β-lactam-ferrocene and β-lactam-ferrocenylchalcone conjugates: synthesis and in vitro anti-tubercular evaluation.
Topics: Alkynes; Antitubercular Agents; Azides; beta-Lactams; Chalcone; Copper; Cycloaddition Reaction; Ferrous Compounds; Metallocenes; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Structure-Activity Relationship; Triazoles | 2013 |
Construction of triazolyl bidentate glycoligands (TBGs) by grafting of 3-azidocoumarin to epimeric pyranoglycosides via a fluorogenic dual click reaction.
Topics: Azides; Click Chemistry; Coumarins; Fluorescent Dyes; Glycosides; Ligands; Stereoisomerism; Triazoles | 2012 |
Synthesis of 5-halogenated 1,2,3-triazoles under stoichiometric Cu(I)-mediated azide-alkyne cycloaddition (CuAAC or 'Click Chemistry').
Topics: Alkynes; Azides; Catalysis; Click Chemistry; Copper; Crystallography, X-Ray; Cycloaddition Reaction; Enzyme Inhibitors; Glycogen Phosphorylase; Halogenation; Humans; Hypoglycemic Agents; Magnetic Resonance Spectroscopy; Molecular Structure; Stereoisomerism; Triazoles | 2012 |
Synthesis, radiolabeling and bioevaluation of a novel arylpiperazine derivative containing triazole as a 5-HT1A receptor imaging agents.
Topics: Animals; Azides; Chemistry Techniques, Synthetic; Click Chemistry; Isotope Labeling; Molecular Imaging; Organotechnetium Compounds; Piperazine; Piperazines; Rats; Receptor, Serotonin, 5-HT1A; Triazoles | 2013 |
"Clickable" vitamin B12 derivative.
Topics: Alkynes; Azides; Click Chemistry; Cycloaddition Reaction; Molecular Structure; Triazoles; Vitamin B 12; Vitamin B Complex | 2013 |
Tris(azidoethyl)amine hydrochloride; a versatile reagent for synthesis of functionalized dumbbell oligodeoxynucleotides.
Topics: Azides; Catalysis; Copper; Indicators and Reagents; Molecular Structure; Oligodeoxyribonucleotides; Triazoles | 2013 |
Alkyne-azide cycloadditions with copper powder in a high-pressure continuous-flow reactor: high-temperature conditions versus the role of additives.
Topics: Alkynes; Antifungal Agents; Azides; Catalysis; Copper; Cycloaddition Reaction; Cycloleucine; Hot Temperature; Isomerism; Pressure; Triazoles | 2013 |
μ-Hydroxyl trinuclear copper(II) clusters: reactivity and unusual formation in the three-component synthesis of 1,2,3-triazoles in aqueous media.
Topics: Alkynes; Azides; Catalysis; Coordination Complexes; Copper; Crystallography, X-Ray; Cycloaddition Reaction; Hydrogen Bonding; Molecular Conformation; Triazoles; Water | 2013 |
Potent naphthoquinones against antimony-sensitive and -resistant Leishmania parasites: synthesis of novel α- and nor-α-lapachone-based 1,2,3-triazoles by copper-catalyzed azide-alkyne cycloaddition.
Topics: Alkynes; Animals; Antimony; Antiprotozoal Agents; Azides; Catalysis; Cell Survival; Cells, Cultured; Copper; Cycloaddition Reaction; Drug Resistance; Leishmania; Leishmania infantum; Macrophages, Peritoneal; Mice; Naphthoquinones; Parasitic Sensitivity Tests; Species Specificity; Triazoles | 2013 |
Synthesis of molecular frameworks containing two distinct heterocycles connected in a single molecule with enhanced three-dimensional shape diversity.
Topics: Alcohols; Alkynes; Azides; Carbohydrates; Cycloaddition Reaction; Pyrazoles; Pyrimidines; Triazoles | 2013 |
Synthesis of 1,5-triazole bridged vancomycin CDE-ring bicyclic mimics using RuAAC macrocyclization.
Topics: Alkynes; Azides; Bridged Bicyclo Compounds; Cyclization; Models, Molecular; Molecular Structure; Organometallic Compounds; Ruthenium; Triazoles; Vancomycin | 2013 |
Alkenes as azido precursors for the one-pot synthesis of 1,2,3-triazoles catalyzed by copper nanoparticles on activated carbon.
Topics: Alkenes; Azides; Carbon; Copper; Cyclization; Metal Nanoparticles; Molecular Structure; Triazoles | 2013 |
Ln[N(SiMe3)2]3-catalyzed cycloaddition of terminal alkynes to azides leading to 1,5-disubstituted 1,2,3-triazoles: new mechanistic features.
Topics: Alkynes; Azides; Catalysis; Cyclization; Lanthanoid Series Elements; Molecular Structure; Organometallic Compounds; Triazoles | 2013 |
"Click-and-click"--hybridised 1,2,3-triazoles supported Cu(I) coordination polymers for azide-alkyne cycloaddition.
Topics: Alkynes; Azides; Click Chemistry; Copper; Cyclization; Models, Molecular; Molecular Structure; Organometallic Compounds; Polymers; Triazoles | 2013 |
Copper-catalyzed Huisgen 1,3-dipolar cycloaddition under oxidative conditions: polymer-assisted assembly of 4-acyl-1-substituted-1,2,3-triazoles.
Topics: Alkynes; Azides; Catalysis; Copper; Cyclization; Molecular Structure; Oxidation-Reduction; Polystyrenes; Thermodynamics; Triazoles | 2013 |
Optimizing the selectivity of DIFO-based reagents for intracellular bioorthogonal applications.
Topics: Acetylglucosamine; Alkynes; Animals; Azides; Caenorhabditis elegans; Catalysis; Click Chemistry; Copper; Cycloaddition Reaction; HeLa Cells; Humans; Indicators and Reagents; Molecular Conformation; Proteins; Sulfhydryl Compounds; Triazoles | 2013 |
Regiocontrolled synthesis of polysubstituted pyrroles starting from terminal alkynes, sulfonyl azides, and allenes.
Topics: Alkynes; Azides; Catalysis; Cyclization; Molecular Structure; Pyrroles; Stereoisomerism; Sulfones; Triazoles | 2013 |
A recyclable ruthenium(II) complex supported on magnetic nanoparticles: a regioselective catalyst for alkyne-azide cycloaddition.
Topics: Alkynes; Azides; Catalysis; Cyclization; Magnetite Nanoparticles; Molecular Structure; Organometallic Compounds; Particle Size; Ruthenium; Stereoisomerism; Surface Properties; Triazoles | 2013 |
Overcoming synthetic challenges of oridonin A-ring structural diversification: regio- and stereoselective installation of azides and 1,2,3-triazoles at the C-1, C-2, or C-3 position.
Topics: Antineoplastic Agents; Azides; Catalysis; Click Chemistry; Diterpenes, Kaurane; Molecular Structure; Stereoisomerism; Triazoles | 2013 |
Efficient microwave assisted synthesis of novel 1,2,3-triazole-sucrose derivatives by cycloaddition reaction of sucrose azides and terminal alkynes.
Topics: Alkynes; Azides; Cyclization; Microwaves; Molecular Conformation; Sucrose; Triazoles | 2013 |
Synthesis and luminescence properties of iridium(III) azide- and triazole-bisterpyridine complexes.
Topics: Azides; Catalysis; Click Chemistry; Copper; Iridium; Luminescence; Molecular Structure; Polymers; Triazoles | 2013 |
Modular synthesis of N-vinyl benzotriazoles.
Topics: Aldehydes; Alkenes; Azides; Cycloaddition Reaction; Molecular Structure; Oxidation-Reduction; Stereoisomerism; Triazoles; Vinyl Compounds | 2013 |
Copper-catalyzed tandem azide-alkyne cycloaddition, Ullmann type C-N coupling, and intramolecular direct arylation.
Topics: Alkynes; Azides; Catalysis; Copper; Cycloaddition Reaction; Heterocyclic Compounds, 4 or More Rings; Hydrocarbons, Brominated; Ligands; Molecular Structure; Triazoles | 2013 |
Facile one-pot assembly of imidazotriazolobenzodiazepines via indium(III)-catalyzed multicomponent reactions.
Topics: Alkynes; Amines; Azides; Catalysis; Cyclization; Heterocyclic Compounds, 4 or More Rings; Indium; Molecular Structure; Triazoles | 2013 |
Stereoselective synthesis of 2,3-dihydropyrroles from terminal alkynes, azides, and α,β-unsaturated aldehydes via N-sulfonyl-1,2,3-triazoles.
Topics: Aldehydes; Alkynes; Azides; Catalysis; Molecular Structure; Pyrroles; Rhodium; Stereoisomerism; Sulfones; Triazoles | 2013 |
Zinc mediated azide-alkyne ligation to 1,5- and 1,4,5-substituted 1,2,3-triazoles.
Topics: Alkynes; Azides; Catalysis; Combinatorial Chemistry Techniques; Cyclization; Ligation; Molecular Structure; Triazoles; Zinc | 2013 |
Iridium-catalyzed cycloaddition of azides and 1-bromoalkynes at room temperature.
Topics: Alkynes; Azides; Catalysis; Cyclization; Cycloaddition Reaction; Hydrocarbons, Brominated; Iridium; Molecular Structure; Temperature; Triazoles | 2013 |
Organocatalytic triazole formation, followed by oxidative aromatization: regioselective metal-free synthesis of benzotriazoles.
Topics: Amines; Azides; Benzoquinones; Catalysis; Click Chemistry; Copper; Cycloaddition Reaction; Pyrrolidines; Stereoisomerism; Triazoles | 2013 |
Observation of the controlled assembly of preclick components in the in situ click chemistry generation of a chitinase inhibitor.
Topics: Azides; Chitinases; Click Chemistry; Crystallization; Models, Molecular; Molecular Structure; Oximes; Quantum Theory; Serratia marcescens; Triazoles | 2013 |
Toward analogues of MraY natural inhibitors: synthesis of 5'-triazole-substituted-aminoribosyl uridines through a Cu-catalyzed azide-alkyne cycloaddition.
Topics: Alkynes; Anti-Bacterial Agents; Azides; Bacterial Proteins; Catalysis; Copper; Cycloaddition Reaction; Drug Resistance, Bacterial; Enzyme Inhibitors; Glycosylation; Transferases; Transferases (Other Substituted Phosphate Groups); Triazoles; Uridine | 2013 |
Direct access to triazole-olefins through catalytic cycloaddition of azides to unsaturated aldehydes.
Topics: Aldehydes; Alkenes; Azides; Catalysis; Cycloaddition Reaction; Molecular Structure; Triazoles | 2013 |
Synthesis of divalent glycoamino acids with bis-triazole linkage.
Topics: Alkynes; Amino Acids; Azides; Catalysis; Copper; Cyclization; Molecular Structure; Triazoles | 2013 |
A copper(I)-catalyzed three-component domino process: assembly of complex 1,2,3-triazolyl-5-phosphonates from azides, alkynes, and H-phosphates.
Topics: Alkynes; Azides; Catalysis; Copper; Hydrogen; Organophosphonates; Oxidation-Reduction; Phosphates; Triazoles | 2013 |
Copper(I)-catalyzed cycloaddition of bismuth(III) acetylides with organic azides: synthesis of stable triazole anion equivalents.
Topics: Azides; Bismuth; Catalysis; Cations, Monovalent; Copper; Cycloaddition Reaction; Organometallic Compounds; Triazoles | 2013 |
Copper-assisted click reactions for activity-based proteomics: fine-tuned ligands and refined conditions extend the scope of application.
Topics: Alkynes; Azides; Click Chemistry; Copper; Cycloaddition Reaction; Ligands; Proteomics; Triazoles; Trifluoroacetic Acid | 2013 |
Synthesis and biological evaluation of nimesulide based new class of triazole derivatives as potential PDE4B inhibitors against cancer cells.
Topics: Alkynes; Apoptosis; Azides; Binding Sites; Catalytic Domain; Cell Line, Tumor; Copper; Cyclic Nucleotide Phosphodiesterases, Type 4; Cycloaddition Reaction; Enzyme Activation; Humans; Molecular Docking Simulation; Phosphodiesterase 4 Inhibitors; Sulfonamides; Triazoles | 2013 |
The electrode as organolithium reagent: catalyst-free covalent attachment of electrochemically active species to an azide-terminated glassy carbon electrode surface.
Topics: Aldehydes; Azides; Carbon; Catalysis; Electrodes; Ethylenediamines; Ferrous Compounds; Indicators and Reagents; Lithium; Metallocenes; Organometallic Compounds; Triazoles | 2013 |
Alkyne-azide cycloaddition catalyzed by silver chloride and "abnormal" silver N-heterocyclic carbene complex.
Topics: Alkynes; Azides; Catalysis; Cycloaddition Reaction; Methane; Silver Compounds; Triazoles | 2013 |
Tandem C-2 functionalization-intramolecular azide-alkyne 1,3-dipolar cycloaddition reaction: a convenient route to highly diversified 9H-benzo[b]pyrrolo[1,2-g][1,2,3]triazolo[1,5-d][1,4]diazepines.
Topics: Alkynes; Azepines; Azides; Catalysis; Heterocyclic Compounds, 4 or More Rings; Molecular Structure; Triazoles | 2014 |
PEG-coumarin based biocompatible self-assembled fluorescent nanoaggregates synthesized via click reactions and studies of aggregation behavior.
Topics: Azides; Biocompatible Materials; Cell Line, Tumor; Cell Survival; Click Chemistry; Coumarins; Drug Carriers; Flocculation; Humans; Hydrophobic and Hydrophilic Interactions; Magnetic Resonance Spectroscopy; Microscopy, Electron, Transmission; Nanostructures; Polyethylene Glycols; Thermodynamics; Triazoles | 2014 |
ZINClick: a database of 16 million novel, patentable, and readily synthesizable 1,4-disubstituted triazoles.
Topics: Alkynes; Azides; Click Chemistry; Databases, Pharmaceutical; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Models, Molecular; Molecular Conformation; NADP; Patents as Topic; Protein Kinase Inhibitors; Small Molecule Libraries; Triazoles | 2014 |
Synthesis of 2,2,4-trimethyl-1,2-dihydroquinolinyl substituted 1,2,3-triazole derivatives: their evaluation as potential PDE 4B inhibitors possessing cytotoxic properties against cancer cells.
Topics: Alkynes; Azides; Binding Sites; Catalysis; Catalytic Domain; Cell Line, Tumor; Cell Survival; Copper; Cyclic Nucleotide Phosphodiesterases, Type 4; Cycloaddition Reaction; Humans; Molecular Docking Simulation; Phosphodiesterase 4 Inhibitors; Triazoles | 2014 |
7-Chloroquinolinotriazoles: synthesis by the azide-alkyne cycloaddition click chemistry, antimalarial activity, cytotoxicity and SAR studies.
Topics: Alkynes; Antimalarials; Azides; Cell Survival; Click Chemistry; Cycloaddition Reaction; Drug Resistance; Hep G2 Cells; Humans; Molecular Structure; Plasmodium falciparum; Structure-Activity Relationship; Triazoles | 2014 |
Synthesis, spectroscopic and theoretical studies of new quasi-podands from bile acid derivatives linked by 1,2,3-triazole rings.
Topics: Azides; Bile Acids and Salts; Click Chemistry; Mass Spectrometry; Models, Theoretical; Triazoles | 2014 |
A highly active and magnetically recoverable tris(triazolyl)-Cu(I) catalyst for alkyne-azide cycloaddition reactions.
Topics: Alkynes; Azides; Catalysis; Cyclization; Cycloaddition Reaction; Molecular Structure; Triazoles | 2014 |
A green, multicomponent, regio- and stereo-selective 1,3-dipolar cycloaddition of azides and azomethine ylides generated in situ with bifunctional dipolarophiles using PEG-400.
Topics: Azides; Azo Compounds; Copper; Cycloaddition Reaction; Green Chemistry Technology; Models, Molecular; Molecular Conformation; Polyethylene Glycols; Stereoisomerism; Substrate Specificity; Thiosemicarbazones; Triazoles | 2014 |
Carbohydrate-based Cu(I) stabilizing ligands and their use in the synthesis of carbohydrate-ferrocene conjugates.
Topics: Alkynes; Azides; Carbohydrates; Catalysis; Click Chemistry; Copper; Ferrous Compounds; Ligands; Metallocenes; Molecular Structure; Triazoles | 2014 |
A convergent synthesis of alkyne-azide cycloaddition derivatives of 4-α,β-2-propyne podophyllotoxin depicting potent cytotoxic activity.
Topics: Alkynes; Antineoplastic Agents; Apoptosis; Azides; Cell Proliferation; Cell Survival; Cyclization; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Podophyllotoxin; Structure-Activity Relationship; Triazoles; Tumor Cells, Cultured | 2014 |
A concomitant allylic azide rearrangement/intramolecular azide-alkyne cycloaddition sequence.
Topics: Alkynes; Azides; Catalysis; Combinatorial Chemistry Techniques; Copper; Cyclization; Cycloaddition Reaction; Iodides; Molecular Structure; Stereoisomerism; Triazoles | 2014 |
Covalently linked plasticizers: triazole analogues of phthalate plasticizers prepared by mild copper-free “click” reactions with azide-functionalized PVC.
Topics: Azides; Click Chemistry; Molecular Structure; Phthalic Acids; Plasticizers; Polymers; Polyvinyl Chloride; Triazoles | 2014 |
Synthesis of pyrroles from terminal alkynes, N-sulfonyl azides, and alkenyl alkyl ethers through 1-sulfonyl-1,2,3-triazoles.
Topics: Alkynes; Azides; Catalysis; Combinatorial Chemistry Techniques; Ethers; Molecular Structure; Pyrroles; Sulfones; Triazoles | 2014 |
Regioselectivity of vinyl sulfone based 1,3-dipolar cycloaddition reactions with sugar azides by computational and experimental studies.
Topics: Azides; Catalysis; Cyclization; Cycloaddition Reaction; Galactosides; Models, Chemical; Molecular Structure; Stereoisomerism; Sulfones; Triazoles | 2014 |
Ce(OTf)₃-catalyzed [3 + 2] cycloaddition of azides with nitroolefins: regioselective synthesis of 1,5-disubstituted 1,2,3-triazoles.
Topics: Alkenes; Azides; Benzyl Compounds; Catalysis; Cycloaddition Reaction; Mesylates; Molecular Structure; Nitro Compounds; Stereoisomerism; Triazoles | 2014 |
Synthesis of 2-aryl-2H-benzotrizoles from azobenzenes and N-sulfonyl azides through sequential rhodium-catalyzed amidation and oxidation in one pot.
Topics: Amides; Azides; Azo Compounds; Catalysis; Molecular Structure; Oxidation-Reduction; Rhodium; Triazoles | 2014 |
Click chemistry inspired synthesis of morpholine-fused triazoles.
Topics: Alkynes; Azides; Click Chemistry; Crystallography, X-Ray; Cyclization; Epichlorohydrin; Magnetic Resonance Spectroscopy; Molecular Structure; Morpholines; Triazoles | 2014 |
Rational construction of triazole/urea based peptidomimetic macrocycles as pseudocyclo-β-peptides and studies on their chirality controlled self-assembly.
Topics: Alkynes; Azides; Copper; Dimerization; Iodides; Models, Molecular; Molecular Conformation; Molecular Structure; Nanotubes; Peptides, Cyclic; Peptidomimetics; Spectroscopy, Fourier Transform Infrared; Stereoisomerism; Triazoles; Urea | 2014 |
New generation of bioorthogonally applicable fluorogenic dyes with visible excitations and large Stokes shifts.
Topics: Azides; Cyclooctanes; Fluorescence; Fluorescent Dyes; Humans; Maltose-Binding Proteins; Optical Imaging; Triazoles | 2014 |
Rapid access to novel 1,2,3-triazolo-heterocyclic scaffolds via tandem Knoevenagel condensation/azide-alkyne 1,3-dipolar cycloaddition reaction in one pot.
Topics: Aldehydes; Alkynes; Azides; Catalysis; Cyclization; Heterocyclic Compounds; Molecular Structure; Triazoles | 2014 |
An azido-BODIPY probe for glycosylation: initiation of strong fluorescence upon triazole formation.
Topics: Azides; Boron Compounds; Cell Line, Tumor; Copper; Cyclization; Fluorescent Dyes; Glycoproteins; Glycosylation; Humans; Lung Neoplasms; Triazoles | 2014 |
1,2,3-Triazoles from carbonyl azides and alkynes: filling the gap.
Topics: Alkynes; Azides; Catalysis; Copper; Cycloaddition Reaction; Triazoles | 2014 |
Pyridine-phosphinimine ligand-accelerated Cu(I)-catalyzed azide-alkyne cycloaddition for preparation of 1-(pyridin-2-yl)-1,2,3-triazole derivatives.
Topics: Alkynes; Azides; Catalysis; Copper; Cycloaddition Reaction; Imines; Ligands; Molecular Conformation; Pyridines; Triazoles | 2014 |
A metal-free three-component reaction for the regioselective synthesis of 1,4,5-trisubstituted 1,2,3-triazoles.
Topics: Aldehydes; Alkanes; Azides; Molecular Structure; Nitro Compounds; Stereoisomerism; Triazoles | 2014 |
Enantiopure 1,4,5-trisubstituted 1,2,3-triazoles from carbohydrates: applications of organoselenium chemistry.
Topics: Aldehydes; Azides; Carbohydrates; Catalysis; Cycloaddition Reaction; Organoselenium Compounds; Stereoisomerism; Triazoles | 2014 |
Ultrasound-assisted synthesis of novel 1,2,3-triazoles coupled diaryl sulfone moieties by the CuAAC reaction, and biological evaluation of them as antioxidant and antimicrobial agents.
Topics: Acoustics; Alkynes; Anti-Bacterial Agents; Antifungal Agents; Antioxidants; Azides; Catalysis; Copper; Cyclization; Dose-Response Relationship, Drug; Fungi; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship; Sulfones; Triazoles; Ultrasonics | 2014 |
Synthesis of triazole-linked homonucleoside polymers through topochemical azide-alkyne cycloaddition.
Topics: Alkynes; Azides; Click Chemistry; Cycloaddition Reaction; DNA; DNA, Single-Stranded; Models, Molecular; Nucleic Acid Conformation; Polymerization; Triazoles | 2014 |
Ruthenium-catalyzed cycloadditions of 1-haloalkynes with nitrile oxides and organic azides: synthesis of 4-haloisoxazoles and 5-halotriazoles.
Topics: Alkynes; Azides; Catalysis; Cyclization; Cycloaddition Reaction; Molecular Structure; Nitriles; Oxides; Ruthenium; Triazoles | 2014 |
An organocatalytic azide-aldehyde [3+2] cycloaddition: high-yielding regioselective synthesis of 1,4-disubstituted 1,2,3-triazoles.
Topics: Aldehydes; Alkynes; Azides; Catalysis; Click Chemistry; Copper; Cycloaddition Reaction; Iridium; Ruthenium; Stereoisomerism; Triazoles | 2014 |
Are 1,4- and 1,5-disubstituted 1,2,3-triazoles good pharmacophoric groups?
Topics: Alkynes; Azides; Binding Sites; Catalysis; Click Chemistry; Copper; Cycloaddition Reaction; Databases, Protein; Protein Structure, Tertiary; Proteins; Ruthenium; Solubility; Static Electricity; Triazoles; Water | 2014 |
New thiosemicarbazides and 1,2,4-triazolethiones derived from 2-(ethylsulfanyl) benzohydrazide as potent antioxidants.
Topics: Antioxidants; Azides; Ferric Compounds; Free Radical Scavengers; Models, Molecular; Molecular Conformation; Semicarbazides; Triazoles | 2014 |
Diastereoselective N-sulfonylaminoalkenylation of azulenes from terminal alkynes and azides via N-sulfonyl-1,2,3-triazoles.
Topics: Alkynes; Azides; Azulenes; Catalysis; Molecular Structure; Rhodium; Stereoisomerism; Sulfones; Triazoles | 2014 |
Synthesis and in vitro antiproliferative evaluation of d-secooxime derivatives of 13β- and 13α-estrone.
Topics: Antineoplastic Agents; Azides; Catalysis; Cell Proliferation; Cycloaddition Reaction; Drug Screening Assays, Antitumor; Estrone; HeLa Cells; Humans; Stereoisomerism; Triazoles | 2014 |
An efficient one-pot strategy for the highly regioselective metal-free synthesis of 1,4-disubstituted-1,2,3-triazoles.
Topics: Alkynes; Azides; Combinatorial Chemistry Techniques; Cycloaddition Reaction; Nitriles; Stereoisomerism; Triazoles | 2014 |
Modular synthesis of bis- and tris-1,2,3-triazoles by permutable sequential azide-aryne and azide-alkyne cycloadditions.
Topics: Alkynes; Azides; Benzene; Cycloaddition Reaction; Triazoles | 2014 |
Helical peptide-foldamers having a chiral five-membered ring amino acid with two azido functional groups.
Topics: Amino Acids; Amino Acids, Cyclic; Azides; Click Chemistry; Crystallography, X-Ray; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Peptides; Spectroscopy, Fourier Transform Infrared; Triazoles | 2014 |
Theoretical studies on the regioselectivity of iridium-catalyzed 1,3-dipolar azide-alkyne cycloaddition reactions.
Topics: Alkynes; Azides; Catalysis; Cycloaddition Reaction; Iridium; Methane; Models, Molecular; Triazoles | 2014 |
Conversion of 2-furylcarbinols with alkyl or aryl azides to highly functionalized 1,2,3-triazoles via cascade formal [3 + 2] cycloaddition/ring-opening.
Topics: Azides; Catalysis; Combinatorial Chemistry Techniques; Cycloaddition Reaction; Furans; Lewis Acids; Molecular Structure; Stereoisomerism; Triazoles | 2014 |
One-pot synthesis of Au@SiO(2) catalysts: a click chemistry approach.
Topics: Alkynes; Azides; Catalysis; Click Chemistry; Cycloaddition Reaction; Gold Compounds; Metal Nanoparticles; Silicon Dioxide; Small Molecule Libraries; Surface-Active Agents; Triazoles | 2014 |
Water-soluble NHC-Cu catalysts: applications in click chemistry, bioconjugation and mechanistic analysis.
Topics: Alkynes; Azides; Basic-Leucine Zipper Transcription Factors; Catalysis; Click Chemistry; Coordination Complexes; Copper; Cycloaddition Reaction; DNA; Drug Discovery; Heterocyclic Compounds; Methane; Models, Molecular; Peptides; Saccharomyces cerevisiae Proteins; Solubility; Thermodynamics; Triazoles; Water | 2014 |
Self-assembly of lipidated pseudopeptidic triazolophanes to vesicles.
Topics: Alkynes; Azides; Click Chemistry; Copper; Cycloaddition Reaction; Lipids; Serine; Triazoles | 2014 |
Microwave-assisted or Cu-NHC-catalyzed cycloaddition of azido-disubstituted alkynes: bifurcation of reaction pathways.
Topics: Alkynes; Amines; Azides; Catalysis; Copper; Cycloaddition Reaction; Microwaves; Molecular Structure; Pargyline; Triazoles | 2014 |
Copper on responsive polymer microgels: a recyclable catalyst exhibiting tunable catalytic activity.
Topics: Alkynes; Azides; Catalysis; Copper; Cyclization; Gels; Molecular Structure; Particle Size; Polymers; Surface Properties; Triazoles | 2014 |
One-pot synthesis of 2,5-dihydropyrroles from terminal alkynes, azides, and propargylic alcohols by relay actions of copper, rhodium, and gold.
Topics: Alkynes; Azides; Catalysis; Combinatorial Chemistry Techniques; Copper; Gold; Propanols; Pyrroles; Rhodium; Triazoles | 2014 |
1,4-disubstituted-[1,2,3]triazolyl-containing analogues of MT-II: design, synthesis, conformational analysis, and biological activity.
Topics: Azides; Chemistry, Pharmaceutical; Copper; Drug Design; HEK293 Cells; Humans; Lactams; Ligands; Linear Models; Magnetic Resonance Spectroscopy; Metallothionein; Molecular Conformation; Peptides; Receptors, Melanocortin; Structure-Activity Relationship; Triazoles | 2014 |
Simple plate-based, parallel synthesis of disulfide fragments using the CuAAC click reaction.
Topics: Alkynes; Azides; Catalysis; Click Chemistry; Copper; Disulfides; Triazoles | 2014 |
Enamine/enolate-mediated organocatalytic azide-carbonyl [3+2] cycloaddition reactions for the synthesis of densely functionalized 1,2,3-triazoles.
Topics: Amines; Azides; Catalysis; Click Chemistry; Cycloaddition Reaction; Stereoisomerism; Triazoles | 2014 |
Defining the potential of aglycone modifications for affinity/selectivity enhancement against medically relevant lectins: synthesis, activity screening, and HSQC-based NMR analysis.
Topics: Acetylglucosamine; Alkynes; Amino Sugars; Azides; Blood Proteins; Carbohydrate Sequence; Catalysis; Cycloaddition Reaction; Galectin 1; Galectin 3; Galectins; Glycosides; Humans; Hydrophobic and Hydrophilic Interactions; Ligands; Models, Molecular; Molecular Sequence Data; Nitrophenylgalactosides; Protein Binding; Structure-Activity Relationship; Triazoles | 2015 |
Chemoselective bioconjugation of triazole phosphonites in aqueous media.
Topics: Adaptor Proteins, Signal Transducing; Alkynes; Azides; Catalysis; Copper; Humans; p120 GTPase Activating Protein; Peptides; Phosphorous Acids; src Homology Domains; Triazoles; Water | 2015 |
Multiplex detection of functional G protein-coupled receptors harboring site-specifically modified unnatural amino acids.
Topics: Amino Acids; Azides; Cyclohexanes; Epitopes; Fluorescent Dyes; HEK293 Cells; Humans; Immunoassay; Maraviroc; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Phenylalanine; Receptors, CCR5; Triazoles | 2015 |
N,N-diethylurea-catalyzed amidation between electron-deficient aryl azides and phenylacetaldehydes.
Topics: Acetaldehyde; Amides; Azides; Catalysis; Dimethyl Sulfoxide; Electrons; Models, Chemical; Molecular Structure; Triazoles; Urea | 2015 |
Mechanism of samarium-catalyzed 1,5-regioselective azide-alkyne [3 + 2]-cycloaddition: a quantum mechanical investigation.
Topics: Alkynes; Azides; Catalysis; Computer Simulation; Cyclization; Gases; Models, Chemical; Quantum Theory; Samarium; Solutions; Solvents; Static Electricity; Surface Properties; Toluene; Triazoles | 2015 |
Ruthenium-catalyzed synthesis of 5-amino-1,2,3-triazole-4-carboxylates for triazole-based scaffolds: beyond the dimroth rearrangement.
Topics: Amino Acids; Azides; Carboxylic Acids; Catalysis; Cycloaddition Reaction; Dipeptides; HSP90 Heat-Shock Proteins; Inhibitory Concentration 50; Peptidomimetics; Ruthenium; Triazoles | 2015 |
Design of new hybrid template by linking quinoline, triazole and dihydroquinoline pharmacophoric groups: A greener approach to novel polyazaheterocycles as cytotoxic agents.
Topics: Antineoplastic Agents; Aza Compounds; Azides; Cell Line, Tumor; Drug Design; Green Chemistry Technology; Humans; Molecular Docking Simulation; Neoplasms; Phosphodiesterase 4 Inhibitors; Quinolines; Triazoles | 2015 |
Regioselective iodoazidation of alkynes: synthesis of α,α-diazidoketones.
Topics: Alkynes; Azides; Catalysis; Cyclization; Ketones; Molecular Structure; Silanes; Succinimides; Triazoles | 2015 |
Functionalized triazolopeptoids--a novel class for mitochondrial targeted delivery.
Topics: Alkynes; Animals; Azides; Catalysis; Cell-Penetrating Peptides; Copper; Cycloaddition Reaction; Drug Carriers; HeLa Cells; Humans; Mitochondria; Peptidomimetics; Triazoles; Zebrafish | 2015 |
Lanthanide complexes of azidophenacyl-DO3A as new synthons for click chemistry and the synthesis of heterometallic lanthanide arrays.
Topics: Azides; Click Chemistry; Coordination Complexes; Lanthanoid Series Elements; Luminescence; Triazoles | 2015 |
Metal-free [3+2] cycloaddition of azides with Tf2C=CH2 for the regioselective preparation of elusive 4-(trifluoromethylsulfonyl)-1,2,3-triazoles.
Topics: Alkenes; Azides; Cycloaddition Reaction; Stereoisomerism; Triazoles | 2015 |
Synthesis of trans-16-triazolyl-13α-methyl-17-estradiol diastereomers and the effects of structural modifications on their in vitro antiproliferative activities.
Topics: Alkynes; Antineoplastic Agents; Apoptosis; Azides; Caspase 3; Caspase 8; Caspase 9; Cell Adhesion; Cell Line; Cell Line, Tumor; Cell Survival; Cisplatin; Cycloaddition Reaction; Estrone; Fibroblasts; Gene Expression Regulation; Humans; Inhibitory Concentration 50; Quantitative Structure-Activity Relationship; Stereoisomerism; Triazoles | 2015 |
One-Pot Synthesis of Glycosyl-β-azido Ester via Diazotransfer Reaction Toward Access of Glycosyl-β-triazolyl Ester.
Topics: Azides; Cyclization; Cycloaddition Reaction; Esters; Glycoconjugates; Magnetic Resonance Spectroscopy; Molecular Structure; Triazoles; X-Ray Diffraction | 2015 |
A stable chemical SUMO1-Ubc9 conjugate specifically binds as a thioester mimic to the RanBP2-E3 ligase complex.
Topics: Alkynes; Azides; Catalysis; Copper; Cycloaddition Reaction; Hydrolysis; Molecular Chaperones; Mutation; Nuclear Pore Complex Proteins; Protein Binding; Protein Stability; Proteolysis; Substrate Specificity; Sulfhydryl Compounds; SUMO-1 Protein; Triazoles; Ubiquitin-Conjugating Enzymes; Ubiquitin-Protein Ligases | 2015 |
Cu (I) catalyzed alkyne-azide 1,3-dipolar cycloaddition (CuAAC): Synthesis of 17α-[1-(substituted phenyl)-1,2,3-triazol-4-yl]-19-nor-testosterone-17β-yl acetates targeting progestational and antipro-liferative activities.
Topics: Alkynes; Animals; Azides; Binding Sites; Catalysis; Cell Line, Tumor; Cell Proliferation; Copper; Cycloaddition Reaction; Female; Molecular Structure; Rats; Receptors, Progesterone; Testosterone; Triazoles; Uterus | 2015 |
Synthetic 1,2,3-triazole-linked glycoconjugates bind with high affinity to human galectin-3.
Topics: Alkynes; Amino Acids; Azides; Blood Proteins; Click Chemistry; Cycloaddition Reaction; Galactosides; Galectin 3; Galectins; Glycoconjugates; Humans; Lactose; Ligands; Molecular Docking Simulation; Molecular Dynamics Simulation; Protein Binding; Triazoles | 2015 |
Cu/Pd-Catalyzed, Three-Component Click Reaction of Azide, Alkyne, and Aryl Halide: One-Pot Strategy toward Trisubstituted Triazoles.
Topics: Alkynes; Azides; Catalysis; Click Chemistry; Copper; Hydrocarbons, Halogenated; Molecular Structure; Palladium; Triazoles | 2015 |
Synthesis of Phospholipid-Protein Conjugates as New Antigens for Autoimmune Antibodies.
Topics: Alkynes; Antigen-Antibody Complex; Antigens; Antiphospholipid Syndrome; Autoantibodies; Azides; beta 2-Glycoprotein I; Click Chemistry; Cycloaddition Reaction; Ethanolamines; Humans; Immunoconjugates; Lupus Erythematosus, Systemic; Protein Binding; Prothrombin; Solutions; Triazoles | 2015 |
N-type pyrazine and triazole-based luminogens with aggregation-enhanced emission characteristics.
Topics: Alkynes; Azides; Catalysis; Copper; Cycloaddition Reaction; Electrons; Pyrazines; Quantum Theory; Ruthenium; Triazoles | 2015 |
Emerging approaches for the synthesis of triazoles: beyond metal-catalyzed and strain-promoted azide-alkyne cycloaddition.
Topics: Alkynes; Azides; Catalysis; Click Chemistry; Cycloaddition Reaction; Isomerism; Ketones; Metals; Triazoles | 2015 |
Strain Promoted Click Chemistry of 2- or 8-Azidopurine and 5-Azidopyrimidine Nucleosides and 8-Azidoadenosine Triphosphate with Cyclooctynes. Application to Living Cell Fluorescent Imaging.
Topics: Adenosine Triphosphate; Alkynes; Azides; Cell Membrane Permeability; Cell Proliferation; Click Chemistry; Cyclooctanes; Fluorescent Dyes; Humans; MCF-7 Cells; Microscopy, Fluorescence; Nucleosides; Pyrimidines; Triazoles | 2015 |
Carbon-Supported Copper Nanomaterials: Recyclable Catalysts for Huisgen [3+2] Cycloaddition Reactions.
Topics: Alkynes; Azides; Carbon; Catalysis; Click Chemistry; Copper; Cycloaddition Reaction; Methane; Models, Molecular; Nanostructures; Nanotubes, Carbon; Triazoles | 2015 |
Synthesis of glycotriazololipids and observations on their self-assembly properties.
Topics: Alkynes; Azides; Click Chemistry; Glycolipids; Temperature; Triazoles | 2015 |
Metal-free cycloaddition to synthesize naphtho[2,3-d][1,2,3]triazole-4,9-diones.
Topics: Alkynes; Azides; Cycloaddition Reaction; Green Chemistry Technology; Triazoles | 2015 |
Luminogenic iridium azide complexes.
Topics: Azides; Cell Line, Tumor; Coordination Complexes; Fluorescent Dyes; Humans; Iridium; Phenanthrolines; Triazoles | 2015 |
Unique tetrameric and hexameric mannoside clusters prepared by click chemistry.
Topics: Alkynes; Anti-Bacterial Agents; Azides; Carbohydrate Conformation; Catalysis; Click Chemistry; Copper; Cycloaddition Reaction; Mannosides; Solubility; Triazoles; Water | 2015 |
Promise of Retinoic Acid-Triazolyl Derivatives in Promoting Differentiation of Neuroblastoma Cells.
Topics: Animals; Azides; Cell Differentiation; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Mass Spectrometry; Mice; Neuroblastoma; Phosphopyruvate Hydratase; Tretinoin; Triazoles | 2016 |
Expedient Synthesis of N1-Substituted Triazole Peptidomimetics.
Topics: Alkynes; Azides; Molecular Structure; Peptides; Peptidomimetics; Triazoles | 2015 |
The topochemical synthesis of triazole-linked homobasic DNA.
Topics: Alkynes; Azides; Cycloaddition Reaction; DNA; Models, Molecular; Triazoles | 2016 |
Synthesis of the copper chelator TGTA and evaluation of its ability to protect biomolecules from copper induced degradation during copper catalyzed azide-alkyne bioconjugation reactions.
Topics: Alkynes; Azides; Catalysis; Chelating Agents; Copper; Cyclization; Galactosides; Molecular Structure; Triazoles | 2016 |
Aminooxylation Horner-Wadsworth-Emmons Sequence for the Synthesis of Enantioenriched γ-Functionalized Vinyl Sulfones.
Topics: Alkynes; Azides; Catalysis; Click Chemistry; Cysteine Proteinase Inhibitors; Molecular Structure; Stereoisomerism; Sulfones; Triazoles | 2016 |
Ribosome-Templated Azide-Alkyne Cycloadditions: Synthesis of Potent Macrolide Antibiotics by In Situ Click Chemistry.
Topics: Alkynes; Anti-Bacterial Agents; Azides; Click Chemistry; Cycloaddition Reaction; Humans; Macrolides; Models, Molecular; Ribosomes; Thermodynamics; Triazoles | 2016 |
Azide-enolate 1,3-dipolar cycloaddition in the synthesis of novel triazole-based miconazole analogues as promising antifungal agents.
Topics: Antifungal Agents; Aspergillus fumigatus; Azides; Candida; Cycloaddition Reaction; Fungi; Humans; Miconazole; Microbial Sensitivity Tests; Mycoses; Rhizopus; Triazoles | 2016 |
Multicomponent Synthesis and Evaluation of New 1,2,3-Triazole Derivatives of Dihydropyrimidinones as Acidic Corrosion Inhibitors for Steel.
Topics: Azides; Benzaldehydes; Catalysis; Corrosion; Pyrimidinones; Steel; Triazoles; Urea | 2016 |
Monitoring mRNA Translation in Neuronal Processes Using Fluorescent Non-Canonical Amino Acid Tagging.
Topics: Alanine; Alkynes; Amino Acids; Animals; Axons; Azides; Cerebral Cortex; Click Chemistry; Dendrites; Disks Large Homolog 4 Protein; Embryo, Mammalian; Fluorescent Dyes; Glycine; Intracellular Signaling Peptides and Proteins; Lab-On-A-Chip Devices; Membrane Proteins; Neurons; Primary Cell Culture; Protein Biosynthesis; Rats, Wistar; RNA, Messenger; Triazoles | 2016 |
CuAAC click chemistry with N-propargyl 1,5-dideoxy-1,5-imino-D-gulitol and N-propargyl 1,6-dideoxy-1,6-imino-D-mannitol provides access to triazole-linked piperidine and azepane pseudo-disaccharide iminosugars displaying glycosidase inhibitory properties.
Topics: 1-Deoxynojirimycin; alpha-Glucosidases; Azides; beta-Amylase; beta-Glucosidase; Click Chemistry; Disaccharides; Enzyme Inhibitors; Glucose; Heterocyclic Compounds, 1-Ring; Hordeum; Imino Sugars; Mannitol; Pargyline; Piperidines; Propylamines; Prunus dulcis; Saccharomyces cerevisiae; Triazoles | 2016 |
Synthesis of a simplified triazole analogue of pateamine A.
Topics: Antineoplastic Agents; Azides; Catalysis; Chemistry Techniques, Synthetic; Copper; Epoxy Compounds; Macrolides; Thiazoles; Triazoles | 2016 |
Synthesis and in Vitro Antiproliferative Evaluation of C-13 Epimers of Triazolyl-d-Secoestrone Alcohols: The First Potent 13α-d-Secoestrone Derivative.
Topics: Alcohols; Alkynes; Azides; Catalysis; Cell Cycle; Cell Proliferation; Cycloaddition Reaction; Humans; MCF-7 Cells; Neoplasms; Triazoles | 2016 |
Chiral Heteroditopic Baskets Designed from Triazolated Calixarenes and Short Peptides.
Topics: Alkynes; Azides; Calixarenes; Catalysis; Cations; Copper; Peptides; Triazoles | 2016 |
Rhodium/Silver-Cocatalyzed Transannulation of N-Sulfonyl-1,2,3-triazoles with Vinyl Azides: Divergent Synthesis of Pyrroles and 2 H-Pyrazines.
Topics: Azides; Catalysis; Cyclization; Pyrazines; Pyrroles; Rhodium; Silver; Triazoles | 2016 |
Antifungal activity of 1'-homo-N-1,2,3-triazol-bicyclic carbonucleosides: A novel type of compound afforded by azide-enolate (3+2) cycloaddition.
Topics: Antifungal Agents; Aspergillus fumigatus; Azides; Cycloaddition Reaction; Dose-Response Relationship, Drug; Microbial Sensitivity Tests; Molecular Conformation; Mucor; Nucleosides; Rhizopus; Structure-Activity Relationship; Triazoles; Trichosporon | 2016 |
Copper Catalysis in Living Systems and In Situ Drug Synthesis.
Topics: Alkynes; Animals; Antineoplastic Agents; Azides; Catalysis; Cell Line; Click Chemistry; Copper; Cycloaddition Reaction; Fluorescent Dyes; HeLa Cells; Humans; Metal Nanoparticles; Triazoles; Zebrafish | 2016 |
Multicomponent Aqueous Synthesis of Iodo-1,2,3-triazoles: Single-Step Models for Dual Modification of Free Peptide and Radioactive Iodo Labeling.
Topics: Alkynes; Azides; Catalysis; Copper; Cycloaddition Reaction; Iodine Radioisotopes; Isotope Labeling; Peptides; Triazoles; Water | 2017 |
Characterization of non-specific protein adsorption induced by triazole groups on the chromatography media using Cu (I)-catalyzed alkyne-azide cycloaddition reaction for ligand immobilization.
Topics: Adsorption; Alkynes; Azides; Catalysis; Chromatography, Agarose; Click Chemistry; Copper; Cycloaddition Reaction; Humans; Ligands; Proteins; Sepharose; Triazoles | 2016 |
Efficient and Regioselectivity-Tunable Metal-Free Polycycloaddition of Activated Azide and Alkynes.
Topics: Alkynes; Azides; Click Chemistry; Cycloaddition Reaction; Molecular Structure; Polymerization; Polymers; Stereoisomerism; Triazoles | 2017 |
Synthesis of bioactive and fluorescent pyridine-triazole-coumarin peptidomimetics through sequential click-multicomponent reactions.
Topics: Alkynes; Antineoplastic Agents; Azides; Catalysis; Cell Survival; Copper; Coumarins; Cycloaddition Reaction; Humans; MCF-7 Cells; Microscopy, Fluorescence; Peptidomimetics; Pyridines; Quantum Theory; Triazoles | 2017 |
Topochemical Azide-Alkyne Cycloaddition Reaction in Gels: Size-Tunable Synthesis of Triazole-Linked Polypeptides.
Topics: Alkynes; Azides; Cycloaddition Reaction; Gels; Hydrogen Bonding; Particle Size; Peptides; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Surface Properties; Triazoles | 2017 |
Ultrasonic-assisted synthesis of 1,4-disubstituted 1,2,3-triazoles via various terminal acetylenes and azide and their quorum sensing inhibition.
Topics: Alkynes; Anti-Bacterial Agents; Azides; Chemistry Techniques, Synthetic; Chromobacterium; Quorum Sensing; Triazoles; Ultrasonic Waves | 2017 |
Synthesis of Poly(phenyltriazolylcarboxylate)s with Aggregation-Induced Emission Characteristics by Metal-Free 1,3-Dipolar Polycycloaddition of Phenylpropiolate and Azides.
Topics: Azides; Cycloaddition Reaction; Molecular Structure; Phenylpropionates; Polymers; Triazoles | 2017 |
Optimized syntheses of Fmoc azido amino acids for the preparation of azidopeptides.
Topics: Alkynes; Amino Acids; Azides; Click Chemistry; Ethylamines; Fluorenes; Peptides; Triazoles; Urea | 2017 |
Tyrosine-Selective Functionalization for Bio-Orthogonal Cross-Linking of Engineered Protein Hydrogels.
Topics: Alkynes; Animals; Azides; Biocompatible Materials; Cell Line; Cell Survival; Click Chemistry; Cross-Linking Reagents; Cycloaddition Reaction; Elastin; Humans; Hydrogels; Mesenchymal Stem Cells; Mice; Neural Stem Cells; Protein Engineering; Triazoles; Tyrosine | 2017 |
Self-assembling Morphologies Obtained from Helical Polycarbodiimide Copolymers and Their Triazole Derivatives.
Topics: Alkynes; Azides; Catalysis; Click Chemistry; Cycloaddition Reaction; Drug Carriers; Microscopy, Atomic Force; Polymerization; Polymers; Triazoles | 2017 |
Kinetics and mechanics of photo-polymerized triazole-containing thermosetting composites via the copper(I)-catalyzed azide-alkyne cycloaddition.
Topics: Alkynes; Azides; Bisphenol A-Glycidyl Methacrylate; Composite Resins; Copper; Cycloaddition Reaction; Kinetics; Materials Testing; Methacrylates; Pliability; Polyethylene Glycols; Polymethacrylic Acids; Stress, Mechanical; Triazoles | 2017 |
Nucleobase azide-ethynylribose click chemistry contributes to stabilizing oligonucleotide duplexes and stem-loop structures.
Topics: Azides; Catalysis; Click Chemistry; Copper; Cycloaddition Reaction; Deoxyribonucleotides; Molecular Structure; Triazoles | 2017 |
Synthesis of d-fructose conjugated ligands via C6 and C1 and their corresponding [Ru(bpy)
Topics: 2,2'-Dipyridyl; Alkynes; Azides; Biological Transport; Catalysis; Click Chemistry; Copper; Fructose; Humans; Ligands; MCF-7 Cells; Organometallic Compounds; Sucrose; Triazoles | 2017 |
Metal-Free Poly-Cycloaddition of Activated Azide and Alkynes toward Multifunctional Polytriazoles: Aggregation-Induced Emission, Explosive Detection, Fluorescent Patterning, and Light Refraction.
Topics: Alkynes; Azides; Catalysis; Cycloaddition Reaction; Fluorescence; Polymerization; Triazoles | 2017 |
Target guided synthesis using DNA nano-templates for selectively assembling a G-quadruplex binding c-MYC inhibitor.
Topics: Alkynes; Azides; Cycloaddition Reaction; DNA; G-Quadruplexes; Gold; Magnetite Nanoparticles; Proto-Oncogene Proteins c-myc; Triazoles | 2017 |
Detection of Alkynes via Click Chemistry with a Brominated Coumarin Azide by Simultaneous Fluorescence and Isotopic Signatures in Mass Spectrometry.
Topics: Alkynes; Amino Acid Sequence; Animals; Antibodies, Monoclonal; Azides; CHO Cells; Click Chemistry; Coumarins; Cricetulus; Fluorescence; Fluorescent Dyes; Halogenation; Humans; Mass Spectrometry; Models, Molecular; Recombinant Proteins; Spectrometry, Fluorescence; Triazoles | 2017 |
Design, Modeling and Synthesis of 1,2,3-Triazole-Linked Nucleoside-Amino Acid Conjugates as Potential Antibacterial Agents.
Topics: Alkynes; Amino Acids; Anti-Bacterial Agents; Azides; Catalysis; Click Chemistry; Copper; Cycloaddition Reaction; Models, Chemical; Molecular Structure; Nucleosides; Triazoles | 2017 |
A General Approach Towards Triazole-Linked Adenosine Diphosphate Ribosylated Peptides and Proteins.
Topics: Adenosine Diphosphate Ribose; ADP-Ribosylation; Alkynes; Azides; Catalysis; Copper; Cycloaddition Reaction; Peptides; Proteins; Triazoles; Ubiquitin | 2018 |
Investigation of copper-free alkyne/azide 1,3-dipolar cycloadditions using microwave irradiation.
Topics: Alkynes; Azides; Cycloaddition Reaction; Microwaves; Models, Molecular; Molecular Structure; Triazoles | 2018 |
Copper-Catalyzed Decarboxylative/Click Cascade Reaction: Regioselective Assembly of 5-Selenotriazole Anticancer Agents.
Topics: Alkynes; Antineoplastic Agents; Azides; Catalysis; Copper; Molecular Structure; Selenium Compounds; Triazoles | 2018 |
Synthesis of novel 17-triazolyl-androst-5-en-3-ol epimers via Cu(I)-catalyzed azide-alkyne cycloaddition and their inhibitory effect on 17α-hydroxylase/C
Topics: Alkynes; Androstenols; Azides; Catalysis; Copper; Cycloaddition Reaction; Enzyme Inhibitors; Lyases; Models, Molecular; Molecular Conformation; Stereoisomerism; Steroid 17-alpha-Hydroxylase; Triazoles | 2018 |
Synthesis of 1-Cyanoalkynes and Their Ruthenium(II)-Catalyzed Cycloaddition with Organic Azides to Afford 4-Cyano-1,2,3-triazoles.
Topics: Alkynes; Azides; Cycloaddition Reaction; Nitriles; Ruthenium; Triazoles | 2018 |
Gene assembly via one-pot chemical ligation of DNA promoted by DNA nanostructures.
Topics: Alkynes; Azides; Click Chemistry; DNA; Green Fluorescent Proteins; Mutation; Nanostructures; Oligodeoxyribonucleotides; Polymerase Chain Reaction; Protein Engineering; Triazoles | 2018 |
Triazole linking for preparation of a next-generation sequencing library from single-stranded DNA.
Topics: Alkynes; Azides; Click Chemistry; Copper; Cycloaddition Reaction; DNA Nucleotidylexotransferase; DNA, Single-Stranded; Gene Library; High-Throughput Nucleotide Sequencing; Micrococcal Nuclease; Oligodeoxyribonucleotides; Saccharomyces cerevisiae; Sequence Analysis, DNA; Triazoles | 2018 |
Post-Synthetic Modification of Oligonucleotides via Orthogonal Amidation and Copper Catalyzed Cycloaddition Reactions.
Topics: Acetylgalactosamine; Amides; Azides; Catalysis; Click Chemistry; Copper; Cycloaddition Reaction; Esterification; HeLa Cells; Humans; Models, Molecular; Oligonucleotides; RNA, Small Interfering; Triazoles | 2018 |
iSPAAC: Isomer-Free Generation of a Bcl-x
Topics: Alkynes; Antineoplastic Agents; Apoptosis; Azides; bcl-X Protein; Cycloaddition Reaction; Humans; Isomerism; K562 Cells; Kinetics; Molecular Docking Simulation; Molecular Weight; Protein Binding; Triazoles | 2018 |
Design, synthesis and biological evaluation of novel 1,2,3-triazole linked coumarinopyrazole conjugates as potent anticholinesterase, anti-5-lipoxygenase, anti-tyrosinase and anti-cancer agents.
Topics: Alkynes; Antineoplastic Agents; Azides; Catalysis; Cell Line, Tumor; Cell Survival; Cholinesterase Inhibitors; Copper; Coumarins; Cycloaddition Reaction; Drug Design; Humans; Inhibitory Concentration 50; Lipoxygenase Inhibitors; Monophenol Monooxygenase; Pyrazoles; Structure-Activity Relationship; Triazoles | 2018 |
A supramolecular hydrogel prepared from a thymine-containing artificial nucleolipid: study of assembly and lyotropic mesophases.
Topics: Alkynes; Azides; Cycloaddition Reaction; Gold; Hydrogels; Liquid Crystals; Nanofibers; Nanotubes; Phosphatidylcholines; Thermodynamics; Thymine; Triazoles | 2018 |
Construction of Functional Hyperbranched Poly(phenyltriazolylcarboxylate)s by Metal-Free Phenylpropiolate-Azide Polycycloaddition.
Topics: Azides; Click Chemistry; Cycloaddition Reaction; Molecular Structure; Phenylpropionates; Polymerization; Polymers; Triazoles | 2018 |
A flow platform for degradation-free CuAAC bioconjugation.
Topics: Alkynes; Azides; Catalysis; Copper; Cycloaddition Reaction; Molecular Structure; Oligonucleotides; Oxidation-Reduction; Peptides; Temperature; Triazoles; Water | 2018 |
Synthesis and Photophysical Studies on N
Topics: Alkynes; Azides; Carbohydrate Conformation; Catalysis; Copper; Coumarins; Cycloaddition Reaction; Photochemical Processes; Triazoles; Uridine | 2018 |
Novel Symmetrical 1,4-Disubstituted-bis-1,2,3-Triazoles: Synthesis by Double CuAAC and Cytotoxicity Evaluation.
Topics: Alkynes; Antineoplastic Agents, Phytogenic; Azides; Catalysis; Cell Proliferation; Cell Survival; Copper; Cycloaddition Reaction; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Structure-Activity Relationship; Triazoles; Tumor Cells, Cultured | 2018 |
Synthesis and Evaluation of Antifungal and Antitrypanosomastid Activities of Symmetrical 1,4-Disubstituted-1,2,3-Bistriazoles Obtained by CuAAC Conditions.
Topics: Alkynes; Antifungal Agents; Azides; Catalysis; Chemistry Techniques, Synthetic; Copper; Fungi; Leishmania; Triazoles; Trypanocidal Agents | 2019 |
Reversal of Tabun Toxicity Enabled by a Triazole-Annulated Oxime Library-Reactivators of Acetylcholinesterase.
Topics: Acetylcholinesterase; Alkynes; Animals; Antibiotic Prophylaxis; Antidotes; Azides; Catalysis; Copper; Female; Kinetics; Mice; Molecular Structure; Organophosphates; Organophosphorus Compounds; Oximes; Triazoles | 2019 |
The application of click chemistry for targeting quadruplex nucleic acids.
Topics: Alkynes; Azides; Catalysis; Click Chemistry; Copper; Cycloaddition Reaction; DNA; G-Quadruplexes; Imides; Triazoles | 2019 |
Synthesis and biological assay of new 2'-deoxyuridine dimers containing a 1,2,3-triazole linker. Part I.
Topics: Alkynes; Antineoplastic Agents; Azides; Biological Assay; Cell Line, Tumor; Cell Survival; Click Chemistry; Cycloaddition Reaction; Deoxyuridine; Dimerization; Drug Discovery; Humans; Nucleosides; Thymidine; Triazoles | 2019 |
Synthesis, characterization and application of copper oxide chitosan nanocomposite for green regioselective synthesis of [1,2,3]triazoles.
Topics: Azides; Catalysis; Chalcone; Chitosan; Copper; Cycloaddition Reaction; Green Chemistry Technology; Models, Molecular; Molecular Conformation; Nanocomposites; Triazoles | 2019 |
Semisynthesis of an Active Enzyme by Quantitative Click Ligation.
Topics: Alkynes; Amino Acids; Azides; Catalysis; Click Chemistry; Enzymes; Triazoles | 2019 |
Artificially Linked Ubiquitin Dimers Characterised Structurally and Dynamically by NMR Spectroscopy.
Topics: Alkynes; Azides; Click Chemistry; Nuclear Magnetic Resonance, Biomolecular; Point Mutation; Protein Structure, Quaternary; Triazoles; Ubiquitin | 2019 |
Synthesis of Benz-Fused Azoles via C-Heteroatom Coupling Reactions Catalyzed by Cu(I) in the Presence of Glycosyltriazole Ligands.
Topics: Azides; Azoles; Catalysis; Copper; Glycosylation; Ligands; Molecular Structure; Quinazolinones; Triazoles | 2019 |
Site-Selective Synthesis of Insulin Azides and Bioconjugates.
Topics: Amino Acid Sequence; Amino Acids; Azides; Cycloaddition Reaction; Humans; Insulin; Recombinant Proteins; Triazoles | 2019 |
Photo-responsive liposomes composed of spiropyran-containing triazole-phosphatidylcholine: investigation of merocyanine-stacking effects on liposome-fiber assembly-transition.
Topics: Alkynes; Azides; Benzopyrans; Catalysis; Copper; Indoles; Lipid Bilayers; Liposomes; Nitro Compounds; Phase Transition; Phosphatidylcholines; Photochemical Processes; Triazoles; Ultraviolet Rays | 2019 |
A Competitive Pull-Down Assay Using G-quadruplex DNA Linked Magnetic Nanoparticles To Determine Specificity of G-quadruplex Ligands.
Topics: Alkynes; Azides; Catalysis; Cell Line, Tumor; Copper; Cycloaddition Reaction; Ferrosoferric Oxide; G-Quadruplexes; Humans; Ligands; Magnetite Nanoparticles; Promoter Regions, Genetic; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-myc; Triazoles | 2019 |
Click Chemistry for Cyclic Peptide Drug Design.
Topics: Alkynes; Azides; Biomimetics; Click Chemistry; Copper; Cyclization; Cycloaddition Reaction; Drug Design; Peptides, Cyclic; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Triazoles | 2019 |
Synthesis of (1,2,3-triazol-4-yl)methyl Phosphinates and (1,2,3-Triazol-4-yl)methyl Phosphates by Copper-Catalyzed Azide-Alkyne Cycloaddition.
Topics: Alkynes; Azides; Chemistry Techniques, Synthetic; Click Chemistry; Copper; Cycloaddition Reaction; Magnetic Resonance Spectroscopy; Phosphates; Triazoles | 2019 |
Ultrasound-assisted Cu(I)-catalyzed azide-alkyne click cycloaddition as polymer-analogous transformation in chitosan chemistry. High antibacterial and transfection activity of novel triazol betaine chitosan derivatives and their nanoparticles.
Topics: Alkynes; Anti-Bacterial Agents; Azides; Betaine; Catalysis; Chitosan; Click Chemistry; Copper; Cycloaddition Reaction; Drug Carriers; HEK293 Cells; Humans; Molecular Weight; Nanoparticles; Transfection; Triazoles; Ultrasonic Waves | 2019 |
Organocatalyzed preparation of 1,4,5-trisubstituted-glycosyl-1,2,3-triazole derivatives.
Topics: Azides; Catalysis; Chemistry Techniques, Synthetic; Chemistry, Pharmaceutical; Cycloaddition Reaction; Glucosides; Humans; Ketones; Molecular Structure; Triazoles | 2019 |
Intramolecular azide-alkene cycloaddition-elimination reaction in an aldohex-2-enonic acid derivative.
Topics: Alkenes; Azides; Cycloaddition Reaction; Enzyme Inhibitors; Molecular Structure; Pyrroles; Triazoles | 2019 |
Water-soluble, stable and azide-reactive strained dialkynes for biocompatible double strain-promoted click chemistry.
Topics: Alkynes; Animals; Azides; Cell Line; Click Chemistry; Cycloaddition Reaction; Escherichia coli; Humans; Mice; Peptides; Protein Binding; Proto-Oncogene Proteins c-mdm2; Solubility; Triazoles; Tumor Suppressor Protein p53; Water | 2019 |
Duplex-forming Oligonucleotide of Triazole-linked RNA.
Topics: Alkynes; Azides; Catalysis; Copper; Cycloaddition Reaction; Molecular Dynamics Simulation; Nucleic Acid Conformation; Oligonucleotides; RNA; Solid-Phase Synthesis Techniques; Triazoles | 2019 |
A numbering-up metal microreactor for the high-throughput production of a commercial drug by copper catalysis.
Topics: Alkynes; Azides; Catalysis; Copper; Cycloaddition Reaction; Microfluidics; Printing, Three-Dimensional; Stainless Steel; Triazoles | 2019 |
An Efficient Approach to Phosphorylated Isoindoline Fused with Triazoles via Zn-Catalyzed Cascade Cyclization of 2-Propynol Benzyl Azides and Diarylphosphine Oxides.
Topics: Alkynes; Azides; Catalysis; Cyclization; Isoindoles; Molecular Structure; Phosphorylation; Propanols; Triazoles; Zinc | 2019 |
Divergent Mechanisms of the Banert Cascade with Propargyl Azides.
Topics: Azides; Kinetics; Triazoles | 2020 |
Self-Healing Metallo-Supramolecular Hydrogel Based on Specific Ni
Topics: Alkynes; Azides; Cycloaddition Reaction; Hydrogels; Ligands; Materials Science; Nickel; Polyethylene Glycols; Polymers; Pyridines; Rheology; Triazoles | 2020 |
Innovative Three-Step Microwave-Promoted Synthesis of
Topics: Aniline Compounds; Azides; Blood Coagulation; Blood Coagulation Tests; Cell Line, Tumor; Cell Survival; Drug Design; Factor Xa; Factor Xa Inhibitors; Humans; Inhibitory Concentration 50; Ligands; Microwaves; Molecular Docking Simulation; Quinolines; Triazoles | 2020 |
A Novel Series of N-aryltriazole and N-acridinyltriazole Hybrids as Potential Anticancer Agents.
Topics: Acridines; Alkynes; Antineoplastic Agents; Azides; Cell Line, Tumor; Cell Proliferation; Click Chemistry; Cycloaddition Reaction; Drug Screening Assays, Antitumor; HEK293 Cells; Humans; Molecular Structure; Structure-Activity Relationship; Triazoles | 2019 |
A theoretical study on the metal-free triazole formation through tandem [3+2] cycloaddition/retro-Diels-Alder reaction of benzyl azide and oxanorbornadienedicarboxylate.
Topics: Azides; Cycloaddition Reaction; Electrons; Models, Molecular; Triazoles | 2020 |
Chiral 1,5-disubstituted 1,2,3-triazoles - versatile tools for foldamers and peptidomimetic applications.
Topics: Alkynes; Azides; Click Chemistry; Cycloaddition Reaction; Models, Molecular; Peptidomimetics; Polymerization; Polymers; Quantum Theory; Stereoisomerism; Thermodynamics; Triazoles | 2020 |
Ce(OTf)
Topics: Alkynes; Azides; Carboxylic Acids; Catalysis; Crystallography, X-Ray; Mesylates; Models, Molecular; Molecular Structure; Nitriles; Oxazoles; Triazoles | 2020 |
Copper-Mediated DNA-Compatible One-Pot Click Reactions of Alkynes with Aryl Borates and TMS-N
Topics: Alkynes; Azides; Borates; Click Chemistry; Copper; Cycloaddition Reaction; DNA; Molecular Structure; Triazoles | 2020 |
C-H Amination Mediated by Cobalt Organoazide Adducts and the Corresponding Cobalt Nitrenoid Intermediates.
Topics: Amination; Azides; Cobalt; Coordination Complexes; Cycloaddition Reaction; Pyrrolidines; Triazoles | 2020 |
Water-Soluble O-, S- and Se-Functionalized Cyclic Acetyl-triaza-phosphines. Synthesis, Characterization and Application in Catalytic Azide-alkyne Cycloaddition.
Topics: Alkynes; Azides; Catalysis; Chemistry Techniques, Synthetic; Cycloaddition Reaction; Magnetic Resonance Spectroscopy; Molecular Structure; Oxygen; Phosphines; Selenium; Solubility; Sulfides; Triazoles; X-Ray Diffraction | 2020 |
A tris(benzyltriazolemethyl)amine-based cage as a CuAAC ligand tolerant to exogeneous bulky nucleophiles.
Topics: Alkynes; Amines; Azides; Click Chemistry; Copper; Cyclization; Ligands; Molecular Structure; Triazoles | 2021 |
The Azide-Allene Dipolar Cycloaddition: Is DFT Able to Predict Site- and Regio-Selectivity?
Topics: Alkadienes; Azides; Cycloaddition Reaction; Cyclopentanes; Density Functional Theory; Molecular Structure; Quantum Theory; Stereoisomerism; Triazoles | 2021 |
1,2,3-Triazole-gold(I)-triethylposphine derivatives active against resistant Gram-positive pathogens.
Topics: Alkynes; Anti-Bacterial Agents; Azides; Catalysis; Click Chemistry; Clostridioides difficile; Cycloaddition Reaction; Drug Discovery; Drug Resistance; Enterococcus; Escherichia coli; Humans; Microbial Sensitivity Tests; Organogold Compounds; Phosphines; Staphylococcus; Triazoles | 2021 |
Copper-Mediated Conversion of Alkynes into Nitriles via Iodotriazoles.
Topics: Alkynes; Azides; Catalysis; Copper; Cycloaddition Reaction; Nitriles; Silanes; Solvents; Triazoles | 2021 |
Investigation of the Click-Chemical Space for Drug Design Using ZINClick.
Topics: Alkynes; Azides; Click Chemistry; Databases, Chemical; Drug Design; Drug Discovery; Small Molecule Libraries; Software; Triazoles | 2021 |
Supramolecular Template-Directed In Situ Click Chemistry: A Bioinspired Approach to Synthesize G-Quadruplex DNA Ligands.
Topics: Alkynes; Azides; Boronic Acids; Catalysis; Click Chemistry; DNA; G-Quadruplexes; Ligands; Molecular Structure; Triazoles | 2021 |
A Modular Approach to Arylazo-1,2,3-triazole Photoswitches.
Topics: Alkynes; Azides; Azo Compounds; Catalysis; Click Chemistry; Molecular Structure; Triazoles | 2021 |
Synthesis and Antitumor Activity of 1-Substituted 1,2,3-Triazole-Mollugin Derivatives.
Topics: A549 Cells; Antineoplastic Agents; Azides; Cell Line, Tumor; Drug Screening Assays, Antitumor; HL-60 Cells; Humans; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; MCF-7 Cells; Molecular Structure; Pyrans; Structure-Activity Relationship; Triazoles | 2021 |
Synthesis of new 1,4-disubstituted 1,2,3-triazoles using the CuAAC reaction and determination of their antioxidant activities.
Topics: Alkynes; Antioxidants; Azides; Cycloaddition Reaction; Triazoles | 2021 |
Luminescent terpyridine appended geminal bisazide and bistriazoles: multinuclear Pt(II) complexes and AIPE-based DNA detection with the naked eye.
Topics: Azides; Biosensing Techniques; Coordination Complexes; DNA; Luminescence; Platinum; Pyridines; Triazoles | 2021 |
Unusual Effect of Impurities on the Spectral Characterization of 1,2,3-Triazoles Synthesized by the Cu-Catalyzed Azide-Alkyne Click Reaction.
Topics: Alkynes; Azides; Catalysis; Click Chemistry; Metals; Triazoles | 2021 |
Preparation of Acidic 5-Hydroxy-1,2,3-triazoles via the Cycloaddition of Aryl Azides with β-Ketoesters.
Topics: Azides; Cycloaddition Reaction; Triazoles | 2021 |
Direct Synthesis of 4-Aryl-1,2,3-triazoles via I
Topics: Azides; Catalysis; Cyclization; Iodides; Triazoles | 2021 |
Copper-Catalyzed Azide-Alkyne Cycloaddition of Hydrazoic Acid Formed
Topics: Alkynes; Azides; Catalysis; Copper; Cycloaddition Reaction; Sodium Azide; Triazoles | 2022 |
Organocatalytic Synthesis and Antitumor Activity of Novel 1,2,3-triazoles Derived from Fatty β-ketoesters.
Topics: Azides; Catalysis; Chemistry Techniques, Synthetic; Cycloaddition Reaction; Humans; Triazoles | 2022 |
Mesoporous epoxidized soybean oil-supported copper-based magnetic nanocatalyst and amberlite-supported azide as a green and efficient catalytic system for 1,2,3-triazole synthesis.
Topics: Azides; Catalysis; Copper; Epoxy Compounds; Magnetic Phenomena; Porosity; Spectroscopy, Fourier Transform Infrared; Triazoles | 2023 |
Enantioselective Rh-Catalyzed Azide-Internal-Alkyne Cycloaddition for the Construction of Axially Chiral 1,2,3-Triazoles.
Topics: Alkynes; Azides; Catalysis; Cycloaddition Reaction; Rhodium; Stereoisomerism; Triazoles | 2022 |
Radical borylation of vinyl azides with NHC-boranes: divergent synthesis of α-boryl ketones and borylated triazoles.
Topics: Azides; Boranes; Ketones; Methane; Triazoles | 2022 |
Mechanistic investigation of enolate/stabilized vinylogous carbanion-mediated organocatalytic azide (3 + 2) cycloaddition reactions for the synthesis of 1,2,3-triazoles.
Topics: Anions; Azides; Carboxylic Acids; Catalysis; Cycloaddition Reaction; Metals; Triazoles | 2022 |
Mechanochemical Promoted Heterocycles: A Solvent-free Route to Triazole Carbohydrates as Glycogen Phosphorylase Inhibitors.
Topics: Alkynes; Animals; Azides; Copper; Enzyme Inhibitors; Glycoconjugates; Glycogen Phosphorylase; Powders; Pyrans; Rabbits; Solvents; Stainless Steel; Triazoles; Water | 2022 |
Synthesis and hemagglutination inhibitory properties of mannose-tipped ligands: The effect of terminal phenyl groups and the linker between the mannose residue and the triazole moiety.
Topics: Azides; Hemagglutination; Humans; Ligands; Mannose; Triazoles | 2022 |
Azido-type-selective triazole formation by iridium-catalyzed cycloaddition with thioalkynes.
Topics: Alkynes; Azides; Catalysis; Copper; Cycloaddition Reaction; Iridium; Triazoles | 2022 |
Easily Functionalized and Readable Sequence-Defined Polytriazoles.
Topics: Azides; Cycloaddition Reaction; Macromolecular Substances; Polymers; Triazoles | 2021 |
A copper-catalysed one-pot hydroboration/azidation/cycloaddition reaction of alkynes.
Topics: Alkynes; Azides; Catalysis; Copper; Cycloaddition Reaction; Triazoles | 2022 |
Ion-Pairing Assemblies of Anion-Responsive π-Electronic Systems Bearing Triazole Moieties Introduced by Click Chemistry.
Topics: Anions; Azides; Click Chemistry; Crystallography, X-Ray; Electronics; Pyrroles; Triazoles | 2022 |
Aza-Oxa-Triazole Based Macrocycles with Tunable Properties: Design, Synthesis, and Bioactivity.
Topics: Alkynes; Azides; Catalysis; Click Chemistry; Copper; Humans; Serum Albumin, Bovine; Triazoles | 2022 |
Azirine-triazole hybrids: selective synthesis of 5-(2
Topics: Azides; Azirines; Ketones; Pyridines; Pyrroles; Triazoles | 2022 |
Internally Functionalized Dendrimers Based on Fully Substituted 1,2,3-Triazoles.
Topics: Azides; Dendrimers; Triazoles | 2022 |
Topochemical Cycloaddition Reaction between an Azide and an Internal Alkyne.
Topics: Alkynes; Azides; Catalysis; Copper; Cycloaddition Reaction; Polymerization; Triazoles | 2022 |
Dual Roles of Azide: Dearomative Dimerization of Furfuryl Azides.
Topics: Alkynes; Azides; Catalysis; Cycloaddition Reaction; Dimerization; Triazoles | 2022 |
Continuous-Flow Direct Azidation of Alcohols and Peroxides for the Synthesis of Quinoxalinone, Benzooxazinone, and Triazole Derivatives.
Topics: Alcohols; Azides; Catalysis; Peroxides; Triazoles | 2022 |
Tuning the Regioselectivity of Topochemical Polymerization through Cocrystallization of the Monomer with an Inert Isostere.
Topics: Acetone; Alkynes; Azides; Chloroform; Polymerization; Polymers; Triazoles | 2022 |
Catalytic activity and mechanistic investigation of 1D 2-Picolinic acid based Cu(II) coordination polymer in the selective construction of 1,4-disubstituted triazoles.
Topics: Alkynes; Azides; Catalysis; Picolinic Acids; Polymers; Triazoles | 2022 |
H-Bond Templated Oligomer Synthesis Using a Covalent Primer.
Topics: Alkynes; Azides; Esters; Nucleic Acids; Oxides; Phenol; Phosphines; Templates, Genetic; Triazoles | 2022 |
On-DNA-1,2,3-Triazole Formation via Click Reaction.
Topics: Alkynes; Azides; Catalysis; Click Chemistry; Copper; Cycloaddition Reaction; DNA; Triazoles | 2022 |
Fluorescent benzofurazan derivatized triazole linked mono and di-glucopyranosyl conjugates: Selective sensing of fluoride ion and coordination features by DFT computation.
Topics: Acetonitriles; Alkynes; Anions; Azides; Benzoxazoles; Fluorides; Fluorine; Spectrometry, Fluorescence; Triazoles | 2022 |
Microwave-Assisted, Metal- and Azide-Free Synthesis of Functionalized Heteroaryl-1,2,3-triazoles via Oxidative Cyclization of N-Tosylhydrazones and Anilines.
Topics: Aniline Compounds; Azides; Cyclization; Lanthanoid Series Elements; Microwaves; Oxidative Stress; Triazoles | 2022 |
Facile Synthesis of Triazoles using Electrospray-Deposited Copper Nanomaterials to Catalyze Azide-Alkyne Cycloaddition (AAC) Click Reactions.
Topics: Alkynes; Azides; Click Chemistry; Copper; Cycloaddition Reaction; Nanostructures; Tandem Mass Spectrometry; Triazoles | 2022 |
Design, Synthesis, Anticancer Activity and Molecular Docking of New 1,2,3-Triazole-Based Glycosides Bearing 1,3,4-Thiadiazolyl, Indolyl and Arylacetamide Scaffolds.
Topics: Alkynes; Antineoplastic Agents; Azides; Cell Proliferation; Doxorubicin; Drug Screening Assays, Antitumor; ErbB Receptors; Glycosides; Humans; MCF-7 Cells; Molecular Docking Simulation; Molecular Structure; Structure-Activity Relationship; Thioglycosides; Triazoles | 2022 |
Pyridyl Glycosyl Triazole/CuI-Mediated Domino/Tandem Synthesis of Quinazolinones.
Topics: Alkynes; Azides; Catalysis; Click Chemistry; Copper; Quinazolinones; Triazoles | 2022 |
Synthesis of fully functionalized spirostanic 1,2,3-triazoles by the three component reaction of diosgenin azides with acetophenones and aryl aldehydes and their biological evaluation as antiproliferative agents.
Topics: Acetophenones; Aldehydes; Antineoplastic Agents; Azides; Diosgenin; Triazoles | 2023 |
One-Pot Synthesis of 2-
Topics: Alkynes; Azides; Carbohydrates; Solvents; Sugars; Triazoles | 2022 |
Mechanochemical Approach towards Multi-Functionalized 1,2,3-Triazoles and Anti-Seizure Drug Rufinamide Analogs Using Copper Beads.
Topics: Alkynes; Azides; Catalysis; Copper; Triazoles | 2022 |
Regioselective Synthesis and Molecular Docking Studies of 1,5-Disubstituted 1,2,3-Triazole Derivatives of Pyrimidine Nucleobases.
Topics: Azides; COVID-19; Humans; Molecular Docking Simulation; SARS-CoV-2; Triazoles | 2022 |
Ruthenium-Catalyzed Cycloaddition for Introducing Chemical Diversity in Second-Generation β-Lactamase Inhibitors.
Topics: Alkynes; Azides; beta-Lactamase Inhibitors; Catalysis; Cycloaddition Reaction; Ruthenium; Triazoles | 2023 |
Synthesis and Fungicide Activity on
Topics: Azides; Fungicides, Industrial; Glycerol; Molecular Docking Simulation; Triazoles; Triose Sugar Alcohols | 2023 |
Modifications of geldanamycin via CuAAC altering affinity to chaperone protein Hsp90 and cytotoxicity.
Topics: Alkynes; Antineoplastic Agents; Azides; Benzoquinones; HSP90 Heat-Shock Proteins; Structure-Activity Relationship; Triazoles | 2023 |
Novel Hybrid Triazoline - Triazole Glycosides: Synthesis, Characterization, Antimicrobial Activity study via In Vitro, and In Silico Means.
Topics: Azides; Ethylene Glycols; Glycosides; Molecular Docking Simulation; Spectroscopy, Fourier Transform Infrared; Triazoles | 2023 |
Synthesis of Functionalized Triazoles on DNA via Azide-Acetonitrile "Click" Reaction.
Topics: Acetonitriles; Alkynes; Azides; Click Chemistry; Cycloaddition Reaction; DNA; Triazoles | 2023 |