Page last updated: 2024-08-23

azides and methotrexate

azides has been researched along with methotrexate in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-199025 (89.29)18.7374
1990's1 (3.57)18.2507
2000's1 (3.57)29.6817
2010's1 (3.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Henderson, GB; Huennekens, FM; Zevely, EM2
Bailey, BD; Goldman, ID; Hill, BT; White, JC1
Shane, B; Stokstad, EL1
Galivan, J1
Briggs, WT; Horne, DW; Wagner, C1
Grossowicz, N; Mandelbaum-Shavit, F2
Baker, ND; Griffin, RJ; Irwin, WJ; Reichert, U; Schmidt, R1
Delcamp, TJ; Freisheim, JH; Price, EM; Ratnam, M; Smith, PL1
Freisheim, JH; Klein, TE; Price, EM; Smith, PL1
Freisheim, JH; Price, EM1
Deliconstantinos, G; Kapoulas, V; Kotsifaki, H1
Fyfe, MJ; Goldman, ID1
Bobzien, WF; Goldman, ID1
Goldman, ID2
Bishop, CF; Melnykovych, G1
Carchman, RA; Fry, DW; Goldman, ID; White, JC1
Gewirtz, DA; Goldman, ID; Randolph, JK; White, JC1
Anderson, LA; Goldman, ID; Matherly, LH1
Cano, JP; Fabre, G; Fabre, I; Goldman, ID; Matherly, LH1
Dembo, M; Moccio, DM; Sirotnak, FM1
Freisheim, JH; McCormick, JI; Susten, SS1
Bailey, BD; Chabner, BA; Schilsky, RL1
Henderson, GB; Zevely, EM1
Cole, SP; Deeley, RG; Létourneau, IJ; Slot, AJ1
Baker, JR; Desai, A; Gordon, CL; Huang, B; Johnson, KB; Kukowska-Latallo, JF; Leroueil, PR; Tang, S; Zong, H1

Other Studies

28 other study(ies) available for azides and methotrexate

ArticleYear
Cyclic adenosine 3':5'-monophosphate and methotrexate transport in L1210 cells.
    Cancer research, 1978, Volume: 38, Issue:3

    Topics: Animals; Azides; Biological Transport, Active; Cells, Cultured; Cyclic AMP; Glucose; Leukemia L1210; Methotrexate; Prostaglandins E; Theophylline; Xanthines

1978
Characteristics of transport of 4-amino antifolates and folate compounds by two lines of L5178Y lymphoblasts, one with impaired transport of methotrexate.
    Cancer research, 1979, Volume: 39, Issue:7 Pt 1

    Topics: 4-Chloromercuribenzenesulfonate; Aminopterin; Animals; Azides; Biological Transport; Cell Line; Cell Membrane; Drug Resistance; Formyltetrahydrofolates; Leukemia, Experimental; Methotrexate; Mice; Tetrahydrofolates

1979
Transport and metabolism of folates by bacteria.
    The Journal of biological chemistry, 1975, Mar-25, Volume: 250, Issue:6

    Topics: Azides; Biological Transport; Enterococcus faecalis; Folic Acid; Glutamates; Hydrogen-Ion Concentration; Iodoacetates; Kinetics; Lacticaseibacillus casei; Methotrexate; Pediococcus; Structure-Activity Relationship; Tetrahydrofolates

1975
The effect of age in culture on the uptake and metabolism of methotrexate by primary cultures of hepatocytes.
    Research communications in chemical pathology and pharmacology, 1979, Volume: 24, Issue:3

    Topics: Animals; Azides; Cells, Cultured; Folic Acid; Liver; Male; Methotrexate; Polyglutamic Acid; Rats; Time Factors

1979
Studies on the transport mechanism of 5-methyltetrahydrofolic acid in freshly isolated hepatocytes: effect of ethanol.
    Archives of biochemistry and biophysics, 1979, Volume: 196, Issue:2

    Topics: Alcohols; Anaerobiosis; Animals; Azides; Biological Transport; Ethanol; In Vitro Techniques; Kinetics; Liver; Male; Methotrexate; Pyrazoles; Rats; Structure-Activity Relationship; Tetrahydrofolates

1979
Photoinactivation of the methotrexate transport system of L1210 cells by 8-azidoadenosin 5'-monophosphate.
    The Journal of biological chemistry, 1979, Oct-25, Volume: 254, Issue:20

    Topics: Adenine Nucleotides; Adenosine Monophosphate; Animals; Azides; Biological Transport; Carrier Proteins; Kinetics; Leukemia L1210; Methotrexate; Mice; Phosphates; Photochemistry; Thiamine Pyrophosphate

1979
Pediococcus cerevisiae mutant with altered transport of folates.
    Journal of bacteriology, 1975, Volume: 123, Issue:2

    Topics: Azides; Binding, Competitive; Biological Transport, Active; Chloromercuribenzoates; Dinitrophenols; Fluorides; Folic Acid; Glucose; Iodoacetates; Isomerism; Kinetics; Leucovorin; Methotrexate; Mutation; Pediococcus; Temperature; Tetrahydrofolates

1975
Uptake, cytotoxicity and metabolism of m-azidopyrimethamine and related lipophilic antifolates in SV-K14 human keratinocytes in vivo.
    Biochemical pharmacology, 1991, Dec-11, Volume: 42 Suppl

    Topics: Animals; Anthralin; Azides; Cell Division; Cell Line, Transformed; Cell Survival; Culture Media; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Folic Acid Antagonists; Humans; In Vitro Techniques; Keratinocytes; Liver; Methotrexate; Mice; Mice, Hairless; Pyrimethamine; Regression Analysis; Skin

1991
Photoaffinity analogues of methotrexate as folate antagonist binding probes.
    Advances in enzyme regulation, 1988, Volume: 27

    Topics: Animals; Azides; Biological Transport; Carrier Proteins; Cell Line; Cell Membrane; Electrophoresis, Polyacrylamide Gel; Folic Acid Antagonists; Leukemia L1210; Methotrexate; Mice; Tetrahydrofolate Dehydrogenase; Tumor Cells, Cultured; Ultraviolet Rays

1988
Photoaffinity analogues of methotrexate as folate antagonist binding probes. 1. Photoaffinity labeling of murine L1210 dihydrofolate reductase and amino acid sequence of the binding region.
    Biochemistry, 1987, Jul-28, Volume: 26, Issue:15

    Topics: Affinity Labels; Amino Acid Sequence; Animals; Azides; Cyanogen Bromide; Folic Acid Antagonists; Kinetics; Leukemia L1210; Methotrexate; Mice; Models, Molecular; Peptide Fragments; Photochemistry; Protein Binding; Protein Conformation

1987
Photoaffinity analogues of methotrexate as folate antagonist binding probes. 2. Transport studies, photoaffinity labeling, and identification of the membrane carrier protein for methotrexate from murine L1210 cells.
    Biochemistry, 1987, Jul-28, Volume: 26, Issue:15

    Topics: Affinity Labels; Animals; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Azides; Carrier Proteins; Cell Membrane; Intracellular Signaling Peptides and Proteins; Kinetics; Leukemia L1210; Methotrexate; Mice; Molecular Weight; Neoplasm Proteins; Structure-Activity Relationship

1987
Targeting of liposomes containing methotrexate towards Tetrahymena pyriformis cells.
    General pharmacology, 1985, Volume: 16, Issue:6

    Topics: Animals; Azides; Cytochalasin B; Deoxyglucose; Endocytosis; Folic Acid Antagonists; Gangliosides; Kinetics; Liposomes; Methotrexate; Phospholipids; Sodium Azide; Tetrahydrofolate Dehydrogenase; Tetrahymena pyriformis; Triterpenes

1985
Carrier-mediated transport of folate in a mutant of Pediococcus cerevisiae.
    Journal of bacteriology, 1973, Volume: 114, Issue:2

    Topics: Aminopterin; Azides; Biological Transport, Active; Carbon Isotopes; Chromatography, Paper; Culture Media; Dinitrophenols; Fluorides; Folic Acid; Hydrogen-Ion Concentration; Iodoacetates; Leucovorin; Methotrexate; Mutation; Pediococcus; Temperature; Tetrahydrofolates

1973
Characteristics of the vincristine-induced augmentation of methotrexate uptake in Ehrlich ascites tumor cells.
    The Journal of biological chemistry, 1973, Jul-25, Volume: 248, Issue:14

    Topics: Animals; Azides; Biological Transport, Active; Carcinoma, Ehrlich Tumor; Cell Division; Cells, Cultured; Chlorides; DNA; Dose-Response Relationship, Drug; Drug Synergism; Glucose; Kinetics; L Cells; Leukemia L1210; Membrane Potentials; Methotrexate; Mice; Tritium; Vincristine; Water

1973
The mechanism of folate transport in rabbit reticulocytes.
    The Journal of clinical investigation, 1972, Volume: 51, Issue:7

    Topics: Animals; Azides; Biological Transport, Active; Erythrocytes; Folic Acid; Iodoacetates; Kinetics; Leukemia L1210; Methotrexate; Rabbits; Reticulocytes; Tetrahydrofolates

1972
The characteristics of the membrane transport of amethopterin and the naturally occurring folates.
    Annals of the New York Academy of Sciences, 1971, Nov-30, Volume: 186

    Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Aspirin; Azides; Biological Transport, Active; Carcinoma, Ehrlich Tumor; Cell Membrane; Cells, Cultured; Chlorides; Erythrocytes; Folic Acid; Humans; Kinetics; Leukemia L1210; Methotrexate; Mice; Nitrates; Organophosphorus Compounds; Phosphates; Rabbits; Sulfates; Time Factors

1971
Specific binding of cortisol in subcellular fractions of HeLa cells: temperature dependence and effects of inhibitors.
    Endocrinology, 1971, Volume: 88, Issue:2

    Topics: 17-Hydroxycorticosteroids; Arsenicals; Azides; Binding Sites; Cell Nucleus; Chloramphenicol; Cyanides; Cycloheximide; Cytoplasm; Dactinomycin; Depression, Chemical; Dinitrophenols; Female; Fluorouracil; HeLa Cells; Hexoses; Humans; Hydrocortisone; In Vitro Techniques; Iodoacetates; Methotrexate; Microsomes; Mitochondria; Ouabain; Prednisolone; Puromycin; Temperature; Tritium

1971
Transport energetics of the folic acid analogue, methotrexate, in L1210 leukemia cells. Enhanced accumulation by metabolic inhibitors.
    The Journal of biological chemistry, 1969, Jul-25, Volume: 244, Issue:14

    Topics: Animals; Azides; Binding Sites; Biological Transport, Active; Diffusion; Electrophysiology; In Vitro Techniques; Kinetics; Leukemia L1210; Methotrexate; Mice; Nitrogen; Pyruvates; Tritium

1969
Relationship between membrane transport of methotrexate and endogenous cyclic adenosine 3':5'-monophosphate in the Ehrlich ascites tumor.
    Cancer research, 1980, Volume: 40, Issue:7

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Ascorbic Acid; Azides; Biological Transport, Active; Carcinoma, Ehrlich Tumor; Cell Membrane; Cells, Cultured; Cholera Toxin; Cyclic AMP; Methotrexate; Mice; Stimulation, Chemical

1980
Transport, binding, and polyglutamation of methotrexate in freshly isolated rat hepatocytes.
    Cancer research, 1980, Volume: 40, Issue:3

    Topics: 4-Chloromercuribenzenesulfonate; Animals; Azides; Biological Transport, Active; Cells, Cultured; Folic Acid; Liver; Male; Methotrexate; Ouabain; Polyglutamic Acid; Rats; Temperature

1980
Role of the cellular oxidation-reduction state in methotrexate binding to dihydrofolate reductase and dissociation induced by reduced folates.
    Cancer research, 1984, Volume: 44, Issue:6

    Topics: Animals; Azides; Carcinoma, Ehrlich Tumor; Folic Acid Antagonists; Glucose; Indicators and Reagents; Kinetics; Leucovorin; Methotrexate; Mice; NAD; NADP; Oxidation-Reduction; Potassium Cyanide; Protein Binding; Rotenone; Sodium Azide; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase

1984
Interactions between 7-hydroxymethotrexate and methotrexate at the cellular level in the Ehrlich ascites tumor in vitro.
    Cancer research, 1984, Volume: 44, Issue:3

    Topics: Animals; Azides; Binding, Competitive; Biological Transport; Carcinoma, Ehrlich Tumor; Folic Acid Antagonists; Glucose; Kinetics; Methotrexate; Mice; Sodium Azide; Tetrahydrofolate Dehydrogenase

1984
Effects of metabolic deprivation on methotrexate transport in L1210 leukemia cells: further evidence for separate influx and efflux systems with different energetic requirements.
    The Journal of membrane biology, 1984, Volume: 78, Issue:1

    Topics: Animals; Azides; Biological Transport, Active; Carrier Proteins; Chlorides; Energy Metabolism; Glucose; Kinetics; Leukemia L1210; Methotrexate; Mice; Models, Biological; Sodium Azide; Tetrahydrofolate Dehydrogenase

1984
Characterization of the methotrexate transport defect in a resistant L 1210 lymphoma cell line.
    Archives of biochemistry and biophysics, 1981, Volume: 212, Issue:1

    Topics: Animals; Azides; Biological Transport; Drug Resistance; Kinetics; Leucovorin; Leukemia L1210; Methotrexate; Mice; Mutation; Tetrahydrofolate Dehydrogenase

1981
Characteristics of membrane transport of methotrexate by cultured human breast cancer cells.
    Biochemical pharmacology, 1981, Jun-15, Volume: 30, Issue:12

    Topics: Azides; Biological Transport, Active; Breast Neoplasms; Cell Line; Cell Membrane; Estradiol; Humans; Insulin; Kinetics; Methotrexate; Neoplasms, Experimental; Sodium Azide; Temperature

1981
Intracellular phosphate and its possible role as an exchange anion for active transport of methotrexate in L1210 cells.
    Biochemical and biophysical research communications, 1982, Jan-29, Volume: 104, Issue:2

    Topics: Animals; Anions; Azides; Biological Transport, Active; Glucose; Kinetics; Leukemia L1210; Methotrexate; Mice; Phosphates; Sodium

1982
Mutational analysis of a highly conserved proline residue in MRP1, MRP2, and MRP3 reveals a partially conserved function.
    Drug metabolism and disposition: the biological fate of chemicals, 2007, Volume: 35, Issue:8

    Topics: Adenosine Triphosphate; Azides; Binding Sites; Cations, Divalent; Cell Line; Cell Membrane; Estradiol; Humans; Leukotriene C4; Membrane Transport Proteins; Methotrexate; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Mutagenesis, Site-Directed; Mutation, Missense; Photochemistry; Proline; Protein Binding; Transfection; Vanadates

2007
The facile synthesis of multifunctional PAMAM dendrimer conjugates through copper-free click chemistry.
    Bioorganic & medicinal chemistry letters, 2012, May-01, Volume: 22, Issue:9

    Topics: Azides; Click Chemistry; Copper; Dendrimers; Drug Delivery Systems; Fluorescein; Folic Acid; Humans; KB Cells; Methotrexate; Nanoparticles

2012