azides has been researched along with diazepam in 77 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 16 (20.78) | 18.7374 |
1990's | 43 (55.84) | 18.2507 |
2000's | 13 (16.88) | 29.6817 |
2010's | 5 (6.49) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Skolnick, P; Wong, G | 2 |
Korpi, ER; Uusi-Oukari, M; Wegelius, K | 1 |
Uusi-Oukari, M | 3 |
Casanova, M; Kleinman, JE; Korpi, ER; Uusi-Oukari, M; Wegelius, K; Zito, M | 1 |
Korpi, ER; Uusi-Oukari, M | 2 |
Olsen, RW; Sapp, DW; Turner, DM | 1 |
Bottlaender, M; Brouillet, E; Chavoix, C; Dodd, RH; Fournier, D; Hantraye, P; Khalili-Varasteh, M; Mazière, M | 1 |
Engel, JA; Söderpalm, B | 1 |
Biggio, G; Concas, A; Sanna, E; Santoro, G; Serra, M | 1 |
Budhram, P; Deacon, RM; Gardner, CR; Thomson, TA | 1 |
Haefely, W | 1 |
Aramo, S; Carcangiu, G; Marrosu, F; Mereu, G; Passino, N | 1 |
Korpi, ER; Malminiemi, O | 1 |
Michael, RP; Schaefer, GJ | 1 |
Biggio, G; Corda, MG; Giorgi, O; Longoni, B | 1 |
Biggio, G; Corda, MG; Fernández, A; Giorgi, O | 1 |
Mehta, AK; Mhatre, M; Ticku, MK | 1 |
Bonetti, EP; Burkard, WP; Gabl, M; Hunkeler, W; Lorez, HP; Martin, JR; Moehler, H; Osterrieder, W; Pieri, L; Polc, P | 1 |
Boi, V; Carcangiu, P; Gessa, GL; Mereu, G; Passino, N | 1 |
Lister, RG; Nutt, DJ | 1 |
Hiltunen, AJ; Järbe, TU | 2 |
Lister, RG | 1 |
Colombo, G; Fadda, F; Gessa, GL; Mosca, E; Niffoi, T | 1 |
Benjamin, D; Harris, CM; Lal, H | 1 |
Kutt, H; Verebely, K | 1 |
Gu, ZQ; Harris, BD; Moody, EJ; Skolnick, P | 1 |
Iwasaki, T; Nakagawa, Y | 1 |
Korpi, ER; Lüddens, H; Mäkelä, R; Wong, G | 1 |
Hansen, HC; Korpi, ER; Suzdak, PD; Uusi-Oukari, M; Wong, G | 1 |
Kettenmann, H; Kleingoor, C; Korpi, ER; Seeburg, PH | 1 |
Cook, JM; Harris, B; Liu, R; Skolnick, P; Zhang, P; Zhang, W | 1 |
Pokk, P; Zharkovsky, A | 1 |
Lüddens, H; Wieland, HA | 1 |
Gardner, CR; Pringle, AK; Walker, RJ | 1 |
Andrews, N; File, SE | 1 |
Abiko, E; Fukuda, H; Ito, Y; Mitani, K | 1 |
Korpi, ER; Seeburg, PH | 1 |
Khan, RM; Soliman, MR | 1 |
Kaivola, J; Korpi, ER; Uusi-Oukari, M | 1 |
Becker, HC; Jarvis, MF | 1 |
File, SE; Hogg, S; Mills, AD | 1 |
Ho, IK; Ito, T; Suzuki, T; Wellman, SE | 1 |
Pruett, SB; Wu, WJ | 1 |
Fukuda, H; Ito, Y; Kobayashi, M; Segawa, K | 1 |
Benke, D; Benson, JA; Carter, DB; Hamilton, BJ; Knoflach, F; Lüddens, H; Mohler, H; Scheurer, L; Wang, Y | 1 |
Liljequist, S; Pokk, P; Zharkovsky, A | 1 |
Benke, D; Michel, C; Mohler, H | 1 |
Firestone, LL; Homanics, GE; Korpi, ER; Mäkelä, R; Quinlan, JJ; Uusi-Oukari, M; Wisden, W | 1 |
Barron, KW; Garrett, KM; Pavelka, SM | 1 |
Acri, JB; Basile, AS; Lyon, T; Witkin, JM; Wong, G | 1 |
Benson, JA; Keist, R; Löw, K; Mohler, H; Rudolph, U | 1 |
Estupinan, LE; France, CP; Gerak, LR | 1 |
France, CP; Gerak, LR | 1 |
Dikic, B; Katsifis, A; Mardon, K; Mattner, F; McPhee, M; Ridley, D | 1 |
Atack, JR; Bristow, L; Brown, N; Carling, RW; Castro, JL; Cook, G; Dawson, GR; Farrar, S; Ferris, P; Garrett, L; Howell, O; Macaulay, A; Marshall, G; McKernan, RM; Moore, KW; Myers, J; Ragan, CI; Reynolds, DS; Rosahl, TW; Street, LJ; Sur, C; Wafford, KA; Whiting, PJ | 1 |
Firestone, LL; Homanics, GE; Quinlan, JJ | 1 |
France, CP; Gerak, LR; Lelas, S | 1 |
Gonzalez, LP; McKenzie, SE; Mhatre, MC | 1 |
Paz, L; Peter, Y; Pick, CG; Weizman, R | 1 |
Arnot, MI; Bateson, AN; Davies, M; Martin, IL | 1 |
France, CP; McMahon, LR | 1 |
Cagetti, E; Liang, J; Olsen, RW; Spigelman, I | 2 |
Hirano, S; Kamei, J; Miyata, S | 1 |
France, CP; Gerak, LR; McMahon, LR | 1 |
Atack, JR; Dawson, GR; Morris, HV; Reynolds, DS; Rosahl, TW; Stephens, DN | 1 |
Glass, JD; McElroy, B; Prosser, RA; Zakaria, A | 1 |
Meera, P; Olsen, RW; Otis, TS; Wallner, M | 1 |
Contó, MB; de Carvalho, JG; Hipólide, DC; Venditti, MA | 1 |
Ishibashi, H; Nabekura, J; Nielsen, M; Witt, MR | 1 |
Banks, ML; Shelton, KL; Tracy, ME | 1 |
Chiou, LC; Fan, PC; Huang, WJ; Lee, HJ; Liao, YH | 1 |
1 review(s) available for azides and diazepam
Article | Year |
---|---|
Cerebellar GABAA receptors and alcohol-related behaviors: focus on diazepam-insensitive [3H]Ro 15-4513 binding.
Topics: Animals; Azides; Behavior; Behavior, Animal; Benzodiazepines; Cerebellum; Diazepam; Ethanol; Humans; Receptors, GABA-A | 1992 |
76 other study(ies) available for azides and diazepam
Article | Year |
---|---|
High affinity ligands for 'diazepam-insensitive' benzodiazepine receptors.
Topics: Animals; Azides; Benzodiazepines; Diazepam; gamma-Aminobutyric Acid; Male; Protein Conformation; Rats; Rats, Inbred Strains; Receptors, GABA-A; Structure-Activity Relationship | 1992 |
Substrate specificity of diazepam-insensitive cerebellar [3H]Ro 15-4513 binding sites.
Topics: Animals; Azides; Behavior, Animal; Benzodiazepines; Binding Sites; Binding, Competitive; Cerebellum; Diazepam; Ethanol; GABA-A Receptor Antagonists; Ligands; Male; Membranes; Rats; Rats, Inbred Strains; Receptors, GABA-A; Sensitivity and Specificity; Substrate Specificity; Tritium | 1992 |
Effect of diethyl pyrocarbonate modification of benzodiazepine receptors on [3H]Ro 15-4513 binding.
Topics: Animals; Appetite Depressants; Azides; Benzodiazepines; Carbolines; Cerebellum; Cerebral Cortex; Diazepam; Diethyl Pyrocarbonate; Flunitrazepam; gamma-Aminobutyric Acid; Hippocampus; Male; Rats; Rats, Inbred Strains; Receptors, GABA-A; Tritium | 1992 |
Characterization of two cerebellar binding sites of [3H]Ro 15-4513.
Topics: Animals; Azides; Benzodiazepines; Binding Sites; Cell Membrane; Cerebellum; Chromatography, Affinity; Diazepam; Flunitrazepam; Receptors, GABA-A; Swine; Tritium | 1992 |
Cerebellar and frontal cortical benzodiazepine receptors in human alcoholics and chronically alcohol-drinking rats.
Topics: Adult; Alcohol Drinking; Alcoholism; Animals; Azides; Benzodiazepines; Brain; Cerebellum; Diazepam; Female; Frontal Lobe; Humans; Ligands; Male; Middle Aged; Models, Biological; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1992 |
Characteristics of two cerebellar binding sites of [3H]Ro 15-4513.
Topics: Animals; Azides; Benzodiazepines; Binding Sites; Cerebellum; Diazepam; In Vitro Techniques; Kinetics; Receptors, GABA-A; Swine; Synaptic Membranes; Synaptosomes | 1992 |
Ro 15-4513 binding to GABAA receptors: subunit composition determines ligand efficacy.
Topics: Animals; Azides; Benzodiazepines; Binding, Competitive; Brain; Cerebellum; Diazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Ligands; Male; Muscimol; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1992 |
The benzodiazepine/alcohol antagonist Ro 15-4513: binding to a GABAA receptor subtype that is insensitive to diazepam.
Topics: Allosteric Regulation; Animals; Azides; Benzodiazepines; Cattle; Cerebellum; Cerebral Cortex; Diazepam; Ethanol; Humans; In Vitro Techniques; Kinetics; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1991 |
In vivo bidirectional modulatory effect of benzodiazepine receptor ligands on GABAergic transmission evaluated by positron emission tomography in non-human primates.
Topics: Animals; Azides; Benzodiazepines; Benzodiazepinones; Binding, Competitive; Carbolines; Cerebral Cortex; Diazepam; Electroencephalography; Flumazenil; gamma-Aminobutyric Acid; Ligands; Male; Papio; Pentylenetetrazole; Receptors, GABA-A; Seizures; Synaptic Transmission; Tomography, Emission-Computed | 1991 |
Involvement of the GABAA/benzodiazepine chloride ionophore receptor complex in the 5,7-DHT Induced anticonflict effect.
Topics: 5,7-Dihydroxytryptamine; Animals; Anti-Anxiety Agents; Azides; Benzodiazepines; Bicuculline; Diazepam; Drinking Behavior; Electroshock; Flumazenil; Hippocampus; Injections, Intraventricular; Limbic System; Male; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Serotonin | 1991 |
Ex vivo binding of t-[35S )butylbicyclophosphorothionate: a biochemical tool to study the pharmacology of ethanol at the gamma-aminobutyric acid-coupled chloride channel.
Topics: Animals; Azides; Benzodiazepines; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlorides; Convulsants; Diazepam; Drug Interactions; Ethanol; gamma-Aminobutyric Acid; Ion Channels; Isoniazid; Male; Rats; Rats, Inbred Strains; Receptors, GABA-A; Sulfur Radioisotopes | 1991 |
Differential interactions of Ro 15-4513 with benzodiazepines, ethanol and pentobarbital.
Topics: Anesthesia; Animals; Anti-Anxiety Agents; Azides; Behavior, Animal; Benzodiazepines; Diazepam; Drug Interactions; Ethanol; Female; Flumazenil; Male; Muscle Contraction; Muscles; Pentobarbital; Rats; Rats, Inbred Strains; Urethane; Vocalization, Animal | 1990 |
Diazepam sensitivity of the binding of an imidazobenzodiazepine, [3H]Ro 15-4513, in cerebellar membranes from two rat lines developed for high and low alcohol sensitivity.
Topics: Affinity Labels; Animals; Azides; Benzodiazepines; Binding Sites; Cerebellum; Diazepam; Drug Tolerance; Ethanol; Membranes; Molecular Weight; Osmolar Concentration; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1990 |
Partial agonists of the benzodiazepine receptor: from animal data to results in patients.
Topics: Affinity Labels; Allosteric Site; Animals; Azides; Benzodiazepines; Benzodiazepinones; Chlordiazepoxide; Chlorides; Clonazepam; Diazepam; Drug Interactions; Ethanol; Flumazenil; Flurazepam; Humans; Ion Channels; Ligands; Models, Neurological; Neurons; Receptors, GABA-A | 1988 |
Antagonism of ethanol effects by Ro 15-4513: an electrophysiological analysis.
Topics: Action Potentials; Animals; Azides; Behavior, Animal; Benzodiazepines; Brain; Diazepam; Dose-Response Relationship, Drug; Electroencephalography; Ethanol; Male; Rats; Rats, Inbred Strains; Receptors, GABA-A; Substantia Nigra | 1989 |
Diazepam-insensitive [3H]Ro 15-4513 binding in intact cultured cerebellar granule cells.
Topics: Animals; Azides; Benzodiazepines; Binding, Competitive; Cell Membrane; Cells, Cultured; Cerebellum; Cytoplasmic Granules; Diazepam; Drug Interactions; Rats | 1989 |
Interactions of diazepam and pentobarbital with RO 15-4513 on intracranial self-stimulation discrimination behavior in rats.
Topics: Animals; Azides; Behavior, Animal; Benzodiazepines; Brain; Diazepam; Discrimination, Psychological; Dose-Response Relationship, Drug; Drug Interactions; Male; Pentobarbital; Rats; Rats, Inbred Strains; Self Stimulation | 1989 |
Decreased sensitivity to diazepam induced by chronic administration of FG 7142.
Topics: Animals; Anticonvulsants; Azides; Benzodiazepines; Brain; Brain Chemistry; Carbolines; Convulsants; Diazepam; Drug Interactions; Male; Motor Activity; Rats; Rats, Inbred Strains; Receptors, GABA-A; Seizures | 1988 |
The abstinence syndrome in diazepam-dependent cats is precipitated by Ro 15-1788 and Ro 15-4513 but not by the benzodiazepine receptor antagonist ZK 93426.
Topics: Animals; Azides; Benzodiazepines; Carbolines; Cats; Diazepam; Flumazenil; Receptors, GABA-A; Substance Withdrawal Syndrome | 1988 |
Chronic ethanol administration increases the binding of the benzodiazepine inverse agonist and alcohol antagonist [3H]RO15-4513 in rat brain.
Topics: Acoustic Stimulation; Animals; Azides; Benzodiazepines; Body Temperature; Brain Chemistry; Diazepam; Ethanol; Flumazenil; Male; Motor Activity; Rats; Rats, Inbred Strains; Receptors, GABA-A; Seizures | 1988 |
Ro 15-4513: partial inverse agonism at the BZR and interaction with ethanol.
Topics: Animals; Azides; Behavior, Animal; Benzodiazepines; Brain; Brain Chemistry; Cats; Diazepam; Dose-Response Relationship, Drug; Drug Interactions; Electrophysiology; Ethanol; Flumazenil; Meta-Analysis as Topic; Mice; Phenobarbital; Rats; Receptors, GABA-A | 1988 |
Electrophysiological evidence that Ro 15-4513 is a benzodiazepine receptor inverse agonist.
Topics: Animals; Azides; Benzodiazepines; Diazepam; Electrophysiology; Ethanol; In Vitro Techniques; Male; Neurons; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1987 |
The effect of the imidazodiazepine Ro 15-4513 on the anticonvulsant effects of diazepam, sodium pentobarbital and ethanol.
Topics: Animals; Azides; Benzodiazepines; Convulsants; Diazepam; Ethanol; Ligands; Male; Mice; Pentobarbital; Receptors, GABA-A | 1987 |
Effects of Ro 15-4513, alone or in combination with ethanol, Ro 15-1788, diazepam, and pentobarbital on instrumental behaviors of rats.
Topics: Animals; Azides; Behavior, Animal; Benzodiazepines; Diazepam; Dose-Response Relationship, Drug; Drug Interactions; Ethanol; Female; Flumazenil; Pentobarbital; Rats; Rats, Inbred Strains; Time Factors | 1988 |
Ethanol and Ro 15-4513: behaviour maintained by operant procedures (DRL-72s and PTZ-drug discrimination) in rats.
Topics: Animals; Azides; Benzodiazepines; Conditioning, Operant; Diazepam; Discrimination Learning; Dose-Response Relationship, Drug; Ethanol; Generalization, Stimulus; Male; Mental Recall; Pentylenetetrazole; Rats; Rats, Inbred Strains; Reinforcement Schedule | 1988 |
Interactions of Ro 15-4513 with diazepam, sodium pentobarbital and ethanol in a holeboard test.
Topics: Animals; Azides; Benzodiazepines; Diazepam; Drug Interactions; Ethanol; Exploratory Behavior; Head; Male; Mice; Motor Activity; Pentobarbital; Posture | 1987 |
Ethanol prevents stress-induced increase in cortical DOPAC: reversal by RO 15-4513.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Azides; Benzodiazepines; Diazepam; Electroshock; Ethanol; Male; Phenylacetates; Rats; Stress, Physiological | 1987 |
Anxiety-like subjective effect of ethanol antagonist RO 15-4513 demonstrated in pentylenetetrazol discrimination.
Topics: Animals; Anxiety; Azides; Benzodiazepines; Diazepam; Discrimination, Psychological; Male; Pentylenetetrazole; Rats | 1987 |
Metabolism of diphenylhydantoin by rat liver microsomes. I. characteristics of the reaction.
Topics: Adenosine Triphosphate; Animals; Azides; Biotransformation; Chlordiazepoxide; Chlorpromazine; Dextropropoxyphene; Diazepam; Diethylstilbestrol; Dimenhydrinate; Disulfiram; Hydantoins; Hydrogen-Ion Concentration; In Vitro Techniques; Isoniazid; Kinetics; Male; Methylene Blue; Microsomes, Liver; NAD; NADP; Oxygen; Phenobarbital; Phenytoin; Proadifen; Prochlorperazine; Rats; Sodium; Temperature | 1970 |
Contribution of "diazepam-insensitive" GABAA receptors to the alcohol antagonist properties of Ro 15-4513 and related imidazobenzodiazepines.
Topics: Alcohol Deterrents; Animals; Azides; Behavior, Animal; Benzodiazepines; Carbolines; Cerebellum; Diazepam; Dose-Response Relationship, Drug; GABA Antagonists; GABA Modulators; GABA-A Receptor Antagonists; Male; Mice; Mice, Inbred Strains | 1995 |
Involvement of benzodiazepine/GABA-A receptor complex in ethanol-induced state-dependent learning in rats.
Topics: Animals; Avoidance Learning; Azides; Benzodiazepines; Bicuculline; Diazepam; Ethanol; Evaluation Studies as Topic; Flumazenil; Male; Muscimol; Picrotoxin; Rats; Rats, Wistar; Reaction Time; Receptors, GABA-A | 1995 |
Phenotypic and genotypic analysis of rats with cerebellar GABAA receptors composed from mutant and wild-type alpha 6 subunits.
Topics: Animals; Azides; Base Sequence; Benzodiazepines; Cerebellum; Diazepam; Genotype; Heterozygote; Molecular Probes; Molecular Sequence Data; Mutation; Phenotype; Rats; Receptors, GABA-A; Recombinant Proteins | 1995 |
Characterization of novel ligands for wild-type and natural mutant diazepam-insensitive benzodiazepine receptors.
Topics: Animals; Azides; Benzodiazepines; Binding, Competitive; Cerebellum; Diazepam; Ethanol; Male; Mutation; Rats; Rats, Wistar; Receptors, GABA-A | 1995 |
Benzodiazepine-induced motor impairment linked to point mutation in cerebellar GABAA receptor.
Topics: Affinity Labels; Amino Acid Sequence; Animals; Arginine; Autoradiography; Azides; Base Sequence; Benzodiazepines; Binding, Competitive; Cerebellum; Diazepam; Drug Tolerance; Ethanol; gamma-Aminobutyric Acid; Histidine; In Situ Hybridization; Kinetics; Macromolecular Substances; Models, Structural; Molecular Sequence Data; Motor Activity; Oligodeoxyribonucleotides; Point Mutation; Poly A; Protein Structure, Secondary; Rats; Rats, Mutant Strains; Receptors, GABA-A; RNA; RNA, Messenger; Tritium | 1993 |
Synthesis of novel imidazobenzodiazepines as probes of the pharmacophore for "diazepam-insensitive" GABAA receptors.
Topics: Affinity Labels; Animals; Azides; Benzodiazepines; Diazepam; Male; Molecular Probes; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Structure-Activity Relationship | 1995 |
The effects of drugs acting at GABA-benzodiazepine-barbiturate receptor complex on the behaviour of sleep-deprived mice.
Topics: Analysis of Variance; Animals; Azides; Behavior, Animal; Benzodiazepines; Convulsants; Diazepam; Flumazenil; Male; Mice; Receptors, GABA-A; Sleep Deprivation | 1995 |
Four amino acid exchanges convert a diazepam-insensitive, inverse agonist-preferring GABAA receptor into a diazepam-preferring GABAA receptor.
Topics: Amino Acid Sequence; Azides; Base Sequence; Benzodiazepines; Binding Sites; Diazepam; GABA Agonists; Humans; Molecular Sequence Data; Mutation; Receptors, GABA-A; Structure-Activity Relationship | 1994 |
Different functional effect of Ro 15-4513 and Ro 19-4603 on synaptic responses of Purkinje cells in the rat cerebellar slice.
Topics: Animals; Azepines; Azides; Benzodiazepines; Cerebellum; Diazepam; Electrophysiology; Flumazenil; In Vitro Techniques; Male; Neural Inhibition; Purkinje Cells; Rats; Rats, Wistar; Receptors, GABA-A; Synapses | 1994 |
F 2692: flumazenil-reversible anxiolytic effects but inactive on [3H]-Ro 15-4513 binding.
Topics: Affinity Labels; Animals; Anti-Anxiety Agents; Azides; Benzodiazepines; Binding, Competitive; Carbolines; Cerebellum; Diazepam; Flumazenil; GABA-A Receptor Antagonists; In Vitro Techniques; Interpersonal Relations; Male; Membranes; Motor Activity; Pyridazines; Rats; Receptors, GABA-A | 1994 |
Characterization of diazepam-insensitive [3H]Ro 15-4513 binding in rodent brain and cultured cerebellar neuronal cells.
Topics: Affinity Labels; Animals; Azides; Benzodiazepines; Binding Sites; Brain; Cell Membrane; Cells, Cultured; Cerebellum; Cerebral Cortex; Diazepam; Guinea Pigs; Hippocampus; Kinetics; Male; Mice; Mice, Inbred Strains; Neurons; Olfactory Bulb; Organ Specificity; Rats; Rats, Wistar; Receptors, GABA-A; Species Specificity; Tritium | 1994 |
Natural mutation of GABAA receptor alpha 6 subunit alters benzodiazepine affinity but not allosteric GABA effects.
Topics: Animals; Azides; Benzodiazepines; Binding Sites; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cell Line; Cerebellum; Cloning, Molecular; Convulsants; Diazepam; gamma-Aminobutyric Acid; Granulocytes; Humans; Kidney; Muscimol; Mutation; Picrotoxin; Rats; Receptors, GABA-A; Recombinant Proteins; Transfection | 1993 |
Effects of benzodiazepine agonist, antagonist and inverse agonist on ethanol-induced changes in beta-endorphin levels in specific rat brain regions.
Topics: Affinity Labels; Animals; Azides; Benzodiazepines; beta-Endorphin; Brain Chemistry; Cerebral Cortex; Diazepam; Ethanol; Flumazenil; Hippocampus; Hypothalamus; Male; Rats; Rats, Sprague-Dawley | 1993 |
Postnatal development of diazepam-insensitive [3H]Ro 15-4513 binding sites.
Topics: Affinity Labels; Aging; Animals; Autoradiography; Azides; Benzodiazepines; Brain; Brain Chemistry; Cerebellum; Cerebral Cortex; Diazepam; Hippocampus; Kinetics; Membranes; Photochemistry; Rats; Rats, Wistar; Receptors, GABA-A; Ultraviolet Rays | 1993 |
Chronic ethanol exposure selectively increases diazepam-insensitive [3H]RO15-4513 binding in mouse cerebellum.
Topics: Administration, Inhalation; Analysis of Variance; Animals; Azides; Benzodiazepines; Binding Sites; Cerebellum; Cerebral Cortex; Diazepam; Ethanol; GABA Modulators; Male; Mice; Mice, Inbred C3H | 1996 |
Differences in benzodiazepine binding in quail selectively bred for differences in tonic immobility.
Topics: Animals; Anti-Anxiety Agents; Azides; Benzodiazepines; Brain; Chlorine; Coturnix; Diazepam; Ethanol; Flunitrazepam; gamma-Aminobutyric Acid; Kinetics; Motor Activity; Radioisotopes; Receptors, GABA-A | 1996 |
Chronic pentobarbital administration alters gamma-aminobutyric acidA receptor alpha 6-subunit mRNA levels and diazepam-insensitive [3H]Ro15-4513 binding.
Topics: Animals; Autoradiography; Azides; Benzodiazepines; Binding, Competitive; Diazepam; In Situ Hybridization; Male; Pentobarbital; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; RNA, Messenger | 1996 |
Suppression of splenic natural killer cell activity in a mouse model for binge drinking. II. Role of the neuroendocrine system.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Alcoholism; Animals; Azides; Benzodiazepines; Carbolines; Catecholamines; Corticosterone; Diazepam; Disease Models, Animal; Female; GABA-A Receptor Agonists; Glucocorticoids; Immunity, Cellular; Immunity, Innate; Killer Cells, Natural; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mifepristone; Nadolol; Naltrexone; Neurosecretory Systems; Oxidopamine; Phentolamine; Picrotoxin; Propranolol; Receptors, GABA-A; Spleen; Sympathetic Nervous System | 1996 |
Inhibition of GABAA ligand-gated Cl- channels by zinc in adult rat brain: a regional study.
Topics: Animals; Azides; Benzodiazepines; Brain; Cerebellum; Cerebral Cortex; Chloride Channels; Chlorides; Diazepam; Hippocampus; Ion Channel Gating; Kinetics; Male; Muscimol; Organ Specificity; Radioligand Assay; Rats; Rats, Wistar; Receptors, GABA-A; Synaptosomes; Tritium; Zinc | 1996 |
Pharmacological modulation of the diazepam-insensitive recombinant gamma-aminobutyric acidA receptors alpha 4 beta 2 gamma 2 and alpha 6 beta 2 gamma 2.
Topics: Animals; Azides; Benzodiazepines; Benzodiazepinones; Binding Sites; Carbolines; Diazepam; Furosemide; GABA Agonists; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Imidazoles; Kinetics; Membrane Potentials; Radioligand Assay; Rats; Receptors, GABA-A; Recombinant Proteins; Sensitivity and Specificity; Zinc | 1996 |
Ro 15-4513 potentiates, instead of antagonizes, ethanol-induced sleep in mice exposed to small platform stress.
Topics: Animals; Anxiety; Azides; Benzodiazepines; Central Nervous System Depressants; Cerebellum; Chlorides; Diazepam; Drug Synergism; Ethanol; GABA Agonists; GABA Modulators; Male; Mice; Muscimol; Receptors, GABA-A; Sleep; Stress, Psychological | 1996 |
GABA(A) receptors containing the alpha4-subunit: prevalence, distribution, pharmacology, and subunit architecture in situ.
Topics: Animals; Azides; Benzodiazepines; Benzodiazepinones; Brain; Cell Membrane; Cerebellum; Diazepam; Flumazenil; Immunohistochemistry; Immunosorbent Techniques; Macromolecular Substances; Male; Muscimol; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Recombinant Proteins | 1997 |
Cerebellar gamma-aminobutyric acid type A receptors: pharmacological subtypes revealed by mutant mouse lines.
Topics: Animals; Azides; Benzodiazepines; Binding Sites; Bridged Bicyclo Compounds, Heterocyclic; Carbolines; Cerebellum; Convulsants; Diazepam; Diuretics; Furosemide; GABA Agonists; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Mice; Mice, Inbred C57BL; Mutation; Pregnanolone; Pyridazines; Receptors, GABA-A; Sulfur Radioisotopes; Tritium; Zinc | 1997 |
Diazepam-sensitive GABA(A) receptors in the NTS participate in cardiovascular control.
Topics: Affinity Labels; Animals; Anti-Anxiety Agents; Autonomic Nervous System; Autoradiography; Azides; Benzodiazepines; Blood Pressure; Brain; Diazepam; Drug Synergism; GABA Agonists; Heart Rate; Isonicotinic Acids; Male; Microinjections; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Solitary Nucleus; Tritium | 1997 |
Localization and pharmacological characterization of pigeon diazepam-insensitive GABAA receptors.
Topics: Affinity Labels; Animals; Autoradiography; Azides; Benzodiazepines; Columbidae; Diazepam; GABA Modulators; gamma-Aminobutyric Acid; Ligands; Male; Radioligand Assay; Receptors, GABA-A | 1997 |
Pharmacology of recombinant gamma-aminobutyric acidA receptors rendered diazepam-insensitive by point-mutated alpha-subunits.
Topics: Amino Acid Sequence; Animals; Azides; Base Sequence; Benzodiazepines; Benzodiazepinones; Cell Line; Diazepam; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Patch-Clamp Techniques; Rats; Receptors, GABA-A; Recombinant Proteins | 1998 |
Ventilatory effects of negative GABA(A) modulators in rhesus monkeys.
Topics: Animals; Azides; Benzodiazepines; Carbolines; Diazepam; Female; GABA Modulators; Macaca mulatta; Male; Receptors, GABA-A; Respiration, Artificial | 1998 |
Discriminative stimulus effects of flumazenil in untreated and in diazepam-treated rhesus monkeys.
Topics: Animals; Azides; Benzodiazepines; Carbolines; Diazepam; Discrimination Learning; Dose-Response Relationship, Drug; Female; Flumazenil; GABA Modulators; Macaca mulatta; Male; Receptors, GABA-A | 1999 |
Synthesis and evaluation of [123I]labelled analogues of the partial inverse agonist Ro 15-4513 for the study of diazepam-insensitive benzodiazepine receptors.
Topics: Animals; Autoradiography; Azides; Benzodiazepines; Brain; Diazepam; Female; Indicators and Reagents; Iodine Radioisotopes; Molecular Structure; Radioligand Assay; Radiopharmaceuticals; Rats; Rats, Wistar; Receptors, GABA-A; Structure-Activity Relationship; Tissue Distribution | 1999 |
Sedative but not anxiolytic properties of benzodiazepines are mediated by the GABA(A) receptor alpha1 subtype.
Topics: Allosteric Site; Animals; Anti-Anxiety Agents; Anticonvulsants; Azides; Benzodiazepines; Binding, Competitive; Brain; Cell Line; Diazepam; Dose-Response Relationship, Drug; Flumazenil; Fluorobenzenes; GABA-A Receptor Antagonists; Hypnotics and Sedatives; Ligands; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Motor Activity; Patch-Clamp Techniques; Receptors, GABA-A; Reflex, Startle; Triazoles | 2000 |
Mice lacking the long splice variant of the gamma 2 subunit of the GABA(A) receptor are more sensitive to benzodiazepines.
Topics: Alternative Splicing; Animals; Azides; Benzodiazepines; Brain; Carbolines; Diazepam; Drug Resistance; Female; Flumazenil; GABA Modulators; Genetic Variation; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Midazolam; Pyridines; Receptors, GABA-A; Sleep; Zolpidem | 2000 |
Antagonism of the discriminative stimulus effects of positive gamma-aminobutyric acid(A) modulators in rhesus monkeys discriminating midazolam.
Topics: Animals; Azides; Benzodiazepines; Carbolines; Diazepam; Discrimination Learning; Drug Antagonism; Female; Flumazenil; GABA Modulators; Macaca mulatta; Male; Midazolam; Receptors, GABA-A | 2000 |
Diazepam during prior ethanol withdrawals does not alter seizure susceptibility during a subsequent withdrawal.
Topics: Affinity Labels; Alcohol Withdrawal Seizures; Animals; Anticonvulsants; Azides; Benzodiazepines; Brain; Central Nervous System Depressants; Diazepam; Electroencephalography; Ethanol; Male; Rats; Rats, Sprague-Dawley | 2001 |
Mice performance on the staircase test following acute ethanol administration.
Topics: Animals; Azides; Benzodiazepines; Central Nervous System Depressants; Diazepam; Dose-Response Relationship, Drug; Ethanol; Flumazenil; GABA Modulators; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred ICR; Psychomotor Performance | 2001 |
GABA(A) receptor gene expression in rat cortex: differential effects of two chronic diazepam treatment regimes.
Topics: Affinity Labels; Animals; Azides; Benzodiazepines; Cerebral Cortex; Diazepam; Dose-Response Relationship, Drug; GABA Modulators; Gene Expression; Infusion Pumps, Implantable; Injections, Subcutaneous; Male; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; RNA, Messenger; Tritium | 2001 |
Daily treatment with diazepam differentially modifies sensitivity to the effects of gamma-aminobutyric acid(A) modulators on schedule-controlled responding in rhesus monkeys.
Topics: Animals; Azides; Benzodiazepines; Carbolines; Conditioning, Operant; Diazepam; Dose-Response Relationship, Drug; Electroshock; Food; GABA Agonists; GABA Antagonists; GABA Modulators; Macaca mulatta; Male; Pentobarbital; Pregnanolone; Receptors, GABA-A; Reinforcement Schedule; Triazolam | 2002 |
Withdrawal from chronic intermittent ethanol treatment changes subunit composition, reduces synaptic function, and decreases behavioral responses to positive allosteric modulators of GABAA receptors.
Topics: Affinity Labels; Alcoholism; Allosteric Regulation; Anesthetics; Animals; Anxiety; Azides; Benzodiazepines; Benzodiazepinones; Binding Sites; Diazepam; Electrophysiology; Ethanol; GABA Modulators; Hippocampus; Hypnosis; Immunoblotting; Kinetics; Male; Maze Learning; Neurons; Pregnanediones; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Reverse Transcriptase Polymerase Chain Reaction; Sleep | 2003 |
Altered pharmacology of synaptic and extrasynaptic GABAA receptors on CA1 hippocampal neurons is consistent with subunit changes in a model of alcohol withdrawal and dependence.
Topics: Alcoholism; Animals; Azides; Benzodiazepines; Diazepam; Drug Interactions; Ethanol; GABA Agonists; Hippocampus; Isoxazoles; Neurons; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Substance Withdrawal Syndrome; Zolpidem | 2004 |
Involvement of diazepam-insensitive benzodiazepine receptors in the suppression of DOI-induced head-twitch responses in diabetic mice.
Topics: Amphetamines; Animals; Azides; Behavior, Animal; Benzodiazepines; Bicuculline; Diabetes Mellitus, Experimental; Diazepam; Flumazenil; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Male; Mice; Mice, Inbred ICR; Receptors, GABA-A; Serotonin Receptor Agonists | 2006 |
Efficacy and the discriminative stimulus effects of negative GABAA modulators, or inverse agonists, in diazepam-treated rhesus monkeys.
Topics: Animals; Azides; Benzodiazepines; Conditioning, Operant; Cues; Diazepam; Discrimination, Psychological; Dose-Response Relationship, Drug; Female; Flumazenil; GABA Agonists; GABA Modulators; Hypnotics and Sedatives; Macaca mulatta; Male; Pentobarbital; Pregnanolone; Receptors, GABA-A | 2006 |
Alpha2-containing GABA(A) receptors are involved in mediating stimulant effects of cocaine.
Topics: Animals; Autoradiography; Azides; Benzodiazepines; Brain Chemistry; Central Nervous System Stimulants; Cocaine; Diazepam; Dose-Response Relationship, Drug; GABA Modulators; Hyperkinesis; Mice; Mice, Knockout; Midazolam; Motor Activity; Protein Subunits; Receptors, GABA-A | 2008 |
Ethanol modulates mammalian circadian clock phase resetting through extrasynaptic GABA receptor activation.
Topics: Animals; Azides; Benzodiazepines; Central Nervous System Depressants; Circadian Rhythm; Diazepam; Dose-Response Relationship, Drug; Ethanol; GABA Antagonists; GABA Modulators; GABA-A Receptor Antagonists; Glutamic Acid; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Photoperiod; Receptors, GABA-A; Serotonin; Suprachiasmatic Nucleus | 2009 |
Alcohol- and alcohol antagonist-sensitive human GABAA receptors: tracking δ subunit incorporation into functional receptors.
Topics: Allosteric Regulation; Animals; Azides; Benzodiazepines; Carbolines; Cations, Divalent; Cell Line; Diazepam; Ethanol; Humans; Mutation; Patch-Clamp Techniques; Protein Subunits; Rats; Receptors, GABA-A; Recombinant Proteins; Transfection; Zinc | 2010 |
Rats with different thresholds for DMCM-induced clonic convulsions differ in the sleep-time of diazepam and [(3)H]-Ro 15-4513 binding.
Topics: Animals; Anticonvulsants; Autoradiography; Azides; Benzodiazepines; Carbolines; Convulsants; Diazepam; Differential Threshold; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Ethanol; Flunitrazepam; GABA Modulators; Male; Pentobarbital; Rats; Rats, Wistar; Reaction Time; Seizures; Sleep; Statistics, Nonparametric; Tritium | 2012 |
Modulation of diazepam-insensitive GABA(A) receptors by micromolar concentrations of thyroxine and related compounds in vitro.
Topics: Affinity Labels; Animals; Azides; Benzodiazepines; Brain; Central Nervous System Depressants; Diazepam; Electrophysiological Phenomena; Ethanol; GABA Modulators; Isoxazoles; Male; Membranes; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, GABA-A; Thyroid Hormones; Thyroxine | 2013 |
Negative allosteric modulation of GABAA receptors inhibits facilitation of brain stimulation reward by drugs of abuse in C57BL6/J mice.
Topics: Allosteric Regulation; Animals; Azides; Benzodiazepines; Brain; Diazepam; Dose-Response Relationship, Drug; Flumazenil; GABA Modulators; gamma-Aminobutyric Acid; Illicit Drugs; Male; Mice; Mice, Inbred C57BL; Microdialysis; Receptors, GABA-A; Reward; Self Stimulation | 2016 |
Hispidulin alleviated methamphetamine-induced hyperlocomotion by acting at α6 subunit-containing GABAA receptors in the cerebellum.
Topics: Allosteric Regulation; Animals; Apomorphine; Azides; Behavior, Animal; Benzodiazepines; Brain; Central Nervous System Stimulants; Cerebellum; Diazepam; Dopamine Agonists; Flavones; GABA Modulators; Humans; Locomotion; Methamphetamine; Mice; Neurons; Receptors, GABA-A; Synaptic Transmission | 2016 |