Page last updated: 2024-08-23

azides and deoxycytidine

azides has been researched along with deoxycytidine in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19905 (20.83)18.7374
1990's1 (4.17)18.2507
2000's1 (4.17)29.6817
2010's12 (50.00)24.3611
2020's5 (20.83)2.80

Authors

AuthorsStudies
Bjursell, G; Skoog, L; Söderman, G; Thelander, L1
Doskocil, J1
Eckstein, F; Hobbs, J; Thelander, L1
Knolle, G1
Komatsu, Y; Tanaka, K1
Cho, MJ; Cory, JG; Kang, SH; Mitchell, BS; Sinhababu, AK; Thakker, DR1
Benkestock, K; Cammack, N; Johansson, NG; Kaiser, AC; Kalayanov, G; Klumpp, K; Le Pogam, S; Leveque, VJ; Maag, H; Maltseva, T; Martin, JA; Najera, I; Rajyaguru, S; Smith, DB; Smith, M; Sund, C; Swallow, S; Winqvist, A; Zhou, XX1
Cavallaro, G; Celia, C; Fresta, M; Giammona, G; Licciardi, M; Paolino, D1
Chang, J; Fan, Q; Guo, X; Jiang, J; Liu, X; Pan, Z; Qi, W; Song, C; Wang, N; Wang, Q; Yu, X; Zhang, Y; Zheng, L1
Bortvin, A; Greenberg, MM; Guan, L; van der Heijden, GW1
An, H; Chang, J; Chen, L; Dong, L; Guo, X; Li, Y; Tao, L; Wang, Q; Yang, X; Yu, X; Zheng, L1
Chang, J; Jiang, J; Sun, C; Wang, Q; Yang, Q; Yang, X; Zhang, Y; Zhao, J; Zheng, L; Zhou, Y1
Chang, J; Gao, C; Gao, Z; Niu, Z; Qin, Z; Song, X; Wang, H; Wang, J; Wang, X1
Aguilar, M; Awad, AM; McNary, J; Samuels, ER1
Chang, JB; Chen, H; Cui, XQ; Dai, SX; Huang, JF; Liu, YJ; Luo, RH; Peng, YM; Wang, RR; Yang, QH; Zhang, XJ; Zheng, YT1
Chang, JB; Ding, XX; Jiang, JH; Ma, F; Wang, CP; Wang, N; Wang, QD; Zhang, Y1
Chang, J; Li, Z; Shi, J; Wang, R; Xie, Y; Yang, L1
Chang, J; Huang, C; Jiang, J; Liu, B; Liu, Y; Peng, Y; Wang, N; Wang, Q; Zhang, Y1
Chang, J; Jiang, J; Liu, B; Liu, Y; Ma, F; Peng, Y; Wang, Q; Wang, Y1
Chai, J; Chang, J; Chen, J; Han, Z; Hou, J; Huang, Z; Jin, X; Li, E; Liang, L; Peng, Y; Qiao, Y; Song, C; Sun, L; Wang, JH; Wang, Q; Wu, M; Yu, W; Zhang, B; Zhang, D; Zhang, Y; Zhao, Q1
Chang, J; Yu, B1
Chang, JB; Che, Y; Cheng, Z; Cui, JJ; Jiang, JD; Li, K; Li, R; Li, SY; Li, YH; Liu, B; Liu, HQ; Liu, Y; Lu, SY; Ma, CX; Peng, XZ; Shao, FM; Sheng, N; Sun, PC; Wan, YH; Wang, C; Wang, CY; Wang, K; Wang, LL; Wang, Z; Yu, SS; Zhang, JL; Zhang, Q; Zhao, LM; Zhu, B1
Deng, G; Li, D; Liu, Y; Shen, M1
Gao, Y; Hu, Z; Luo, Z; Ma, Y1

Other Studies

24 other study(ies) available for azides and deoxycytidine

ArticleYear
2'-Deoxy-2'-azidocytidine inhibits the initiation of polyoma DNA synthesis.
    Proceedings of the National Academy of Sciences of the United States of America, 1977, Volume: 74, Issue:12

    Topics: Azides; Cell Line; Chromosome Mapping; Cytidine; Deoxycytidine; DNA Replication; DNA Restriction Enzymes; DNA, Viral; Electrophoresis, Agar Gel; Microscopy, Electron; Molecular Weight; Polyomavirus; Virus Replication

1977
The role of thiol groups in nucleoside transport.
    Molecular and cellular biochemistry, 1976, Feb-25, Volume: 10, Issue:3

    Topics: Arsenates; Azides; Biological Transport, Active; Chloromercuribenzoates; Deoxycytidine; Deoxyribonucleosides; Dinitrophenols; Drug Resistance, Microbial; Escherichia coli; Ethylmaleimide; Guanosine; Iodoacetates; Kinetics; Ribonucleosides; Showdomycin; Sulfhydryl Reagents

1976
The active site of ribonucleoside diphosphate reductase.
    Methods in enzymology, 1977, Volume: 46

    Topics: Azides; Binding Sites; Deoxycytidine; Deoxyuridine; Molecular Weight; Ribonucleoside Diphosphate Reductase; Ribonucleotide Reductases

1977
[Antiviral therapy of HIV-infection].
    Die Quintessenz, 1988, Volume: 39, Issue:1

    Topics: Antiviral Agents; Azides; Deoxycytidine; HIV Seropositivity; Humans; Interferons

1988
Deoxycytidine uptake by isolated membrane vesicles from Escherichia coli K 12.
    Biochimica et biophysica acta, 1973, Jul-18, Volume: 311, Issue:4

    Topics: Ascorbic Acid; Azides; Biological Transport; Carbon Isotopes; Cell Fractionation; Cell Membrane; Chloromercuribenzoates; Deoxycytidine; Deoxyribonucleosides; Electron Transport; Escherichia coli; Iodoacetates; Lactates; Mutation; NAD; Nucleosides; Organoids; Proline; Succinates; Thymidine; Time Factors; Uridine

1973
Cellular delivery of nucleoside diphosphates: a prodrug approach.
    Pharmaceutical research, 1997, Volume: 14, Issue:6

    Topics: Animals; Antineoplastic Agents; Azides; Cell Division; Cell Line; CHO Cells; Cricetinae; Cytidine Diphosphate; Deoxycytidine; Deoxycytidine Kinase; Deoxyuracil Nucleotides; Deoxyuridine; Dideoxynucleotides; Hydrolysis; Permeability; Phosphorylation; Prodrugs; Ribonucleotide Reductases; Tumor Cells, Cultured; Uridine Monophosphate

1997
The design, synthesis, and antiviral activity of monofluoro and difluoro analogues of 4'-azidocytidine against hepatitis C virus replication: the discovery of 4'-azido-2'-deoxy-2'-fluorocytidine and 4'-azido-2'-dideoxy-2',2'-difluorocytidine.
    Journal of medicinal chemistry, 2009, May-14, Volume: 52, Issue:9

    Topics: Antiviral Agents; Azides; Cell Line, Tumor; Deoxycytidine; Drug Design; Hepacivirus; Humans; Virus Replication

2009
Folate-targeted supramolecular vesicular aggregates based on polyaspartyl-hydrazide copolymers for the selective delivery of antitumoral drugs.
    Biomaterials, 2010, Volume: 31, Issue:28

    Topics: Antineoplastic Agents; Azides; Biocompatible Materials; Cell Line, Tumor; Deoxycytidine; Drug Carriers; Drug Delivery Systems; Folic Acid; Gemcitabine; Humans; Materials Testing; Microscopy, Confocal; Molecular Structure; Peptides; Polymers; Tissue Distribution

2010
FNC, a novel nucleoside analogue inhibits cell proliferation and tumor growth in a variety of human cancer cells.
    Biochemical pharmacology, 2011, Apr-01, Volume: 81, Issue:7

    Topics: Animals; Antineoplastic Agents; Azides; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Deoxycytidine; Humans; Inhibitory Concentration 50; Mice

2011
Intracellular detection of cytosine incorporation in genomic DNA by using 5-ethynyl-2'-deoxycytidine.
    Chembiochem : a European journal of chemical biology, 2011, Sep-19, Volume: 12, Issue:14

    Topics: Alkynes; Animals; Azides; Base Sequence; Copper; Cytosine; Deoxycytidine; Deoxycytosine Nucleotides; DNA; DNA Repair; DNA Replication; DNA-Directed DNA Polymerase; Female; Fluorescent Dyes; Genome; Intracellular Space; Male; Mice; Molecular Probe Techniques; Spermatozoa; Zygote

2011
Antiviral activity of FNC, 2'-deoxy-2'-β-fluoro-4'-azidocytidine, against human and duck HBV replication.
    Antiviral therapy, 2012, Volume: 17, Issue:4

    Topics: Animals; Antiviral Agents; Azides; Cell Line, Tumor; Deoxycytidine; Ducks; Hepatitis B; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatocytes; Humans; Lamivudine; Liver; Virus Replication

2012
Novel nucleoside analogue FNC is effective against both wild-type and lamivudine-resistant HBV clinical isolates.
    Antiviral therapy, 2012, Volume: 17, Issue:8

    Topics: Adult; Antiviral Agents; Azides; Cell Line; Cell Survival; Deoxycytidine; Drug Resistance, Viral; Genotype; Hep G2 Cells; Hepatitis B virus; Humans; Male; Virus Replication

2012
The pyrimidine analog FNC inhibits cell proliferation and viral protein synthesis in HTLV‑1‑infected cells.
    Molecular medicine reports, 2013, Volume: 7, Issue:5

    Topics: Azides; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Deoxycytidine; G1 Phase Cell Cycle Checkpoints; HTLV-I Infections; Human T-lymphotropic virus 1; Humans; Protein Biosynthesis; Pyrimidines; S Phase; Viral Proteins

2013
Effective synthesis of 3'-deoxy-3'-azido nucleosides for antiviral and antisense ribonucleic guanidine (RNG) applications.
    Nucleosides, nucleotides & nucleic acids, 2013, Volume: 32, Issue:3

    Topics: Azides; Deoxycytidine; Deoxyuridine; Nucleic Acid Conformation; Oligodeoxyribonucleotides; RNA, Antisense

2013
Azvudine, a novel nucleoside reverse transcriptase inhibitor showed good drug combination features and better inhibition on drug-resistant strains than lamivudine in vitro.
    PloS one, 2014, Volume: 9, Issue:8

    Topics: Anti-HIV Agents; Azides; Cell Line; Deoxycytidine; Drug Resistance, Viral; Genotype; HIV; HIV Reverse Transcriptase; Humans; Lamivudine; Microbial Sensitivity Tests; Models, Molecular; Molecular Conformation; Protein Binding; Reverse Transcriptase Inhibitors; Virus Replication

2014
FNC, a novel nucleoside analogue, blocks invasion of aggressive non-Hodgkin lymphoma cell lines via inhibition of the Wnt/β-catenin signaling pathway.
    Asian Pacific journal of cancer prevention : APJCP, 2014, Volume: 15, Issue:16

    Topics: Antineoplastic Agents; Azides; beta Catenin; Cadherins; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Proliferation; Deoxycytidine; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Lymphoma, Non-Hodgkin; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Neoplasm Invasiveness; RNA, Messenger; Vascular Endothelial Growth Factor A; Wnt Proteins; Wnt Signaling Pathway

2014
Investigation of the binding between pepsin and nucleoside analogs by spectroscopy and molecular simulation.
    Journal of fluorescence, 2015, Volume: 25, Issue:2

    Topics: Azides; Deoxycytidine; Energy Transfer; Molecular Docking Simulation; Pepsin A; Protein Binding; Protein Conformation; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Temperature

2015
Intestinal absorption mechanisms of 2'-deoxy-2'-β-fluoro-4'-azidocytidine, a cytidine analog for AIDS treatment, and its interaction with P-glycoprotein, multidrug resistance-associated protein 2 and breast cancer resistance protein.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2017, Jul-15, Volume: 105

    Topics: Acquired Immunodeficiency Syndrome; Animals; Anti-HIV Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; Azides; Caco-2 Cells; Deoxycytidine; Humans; Intestinal Absorption; Intestine, Small; Male; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Rats, Sprague-Dawley

2017
Effects of the antiretroviral drug 2'-deoxy-2'-β-fluoro-4'-azidocytidine (FNC) on P-gp, MRP2 and BCRP expressions and functions.
    Die Pharmazie, 2018, 09-01, Volume: 73, Issue:9

    Topics: Animals; Anti-HIV Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; Azides; Biological Transport; Caco-2 Cells; Deoxycytidine; Drug Interactions; Humans; Intestinal Absorption; Male; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Rats; Rats, Sprague-Dawley; Up-Regulation

2018
Mechanistic Insight into Antiretroviral Potency of 2'-Deoxy-2'-β-fluoro-4'-azidocytidine (FNC) with a Long-Lasting Effect on HIV-1 Prevention.
    Journal of medicinal chemistry, 2020, 08-13, Volume: 63, Issue:15

    Topics: Animals; Anti-HIV Agents; Azides; Deoxycytidine; HIV Infections; HIV-1; Humans; Lamivudine; Macaca mulatta; Models, Molecular; Reverse Transcriptase Inhibitors; Ubiquitination

2020
Azvudine (FNC): a promising clinical candidate for COVID-19 treatment.
    Signal transduction and targeted therapy, 2020, 10-10, Volume: 5, Issue:1

    Topics: Azides; Betacoronavirus; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Deoxycytidine; Humans; Pandemics; Pilot Projects; Pneumonia, Viral; SARS-CoV-2; Tablets

2020
Azvudine is a thymus-homing anti-SARS-CoV-2 drug effective in treating COVID-19 patients.
    Signal transduction and targeted therapy, 2021, 12-06, Volume: 6, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Animals; Antiviral Agents; Azides; Coronavirus OC43, Human; COVID-19 Drug Treatment; Deoxycytidine; Female; Humans; Male; Middle Aged; Rats; SARS-CoV-2; Thymus Gland

2021
Evaluate clinical effectiveness of Azvudine with data rather than speculation.
    Journal of medical virology, 2023, Volume: 95, Issue:7

    Topics: Azides; Deoxycytidine; Humans; Treatment Outcome

2023
Real-world effectiveness of azvudine: Elixir or equivocal answer?
    Journal of medical virology, 2023, Volume: 95, Issue:7

    Topics: Azides; Deoxycytidine; Humans

2023