Compounds > azetidine-2,4-dicarboxylic acid
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azetidine-2,4-dicarboxylic acid and glycine

azetidine-2,4-dicarboxylic acid has been researched along with glycine in 6 studies

Compound Research Comparison

Studies
(azetidine-2,4-dicarboxylic acid)		Trials
(azetidine-2,4-dicarboxylic acid)		Recent Studies (post-2010)
(azetidine-2,4-dicarboxylic acid)		Studies
(glycine)		Trials
(glycine)		Recent Studies (post-2010) (glycine)
200035,1637568,415

Protein Interaction Comparison

ProteinTaxonomyazetidine-2,4-dicarboxylic acid (IC50)glycine (IC50)
Glutamate receptor ionotropic, NMDA 1 Rattus norvegicus (Norway rat)1.4852
Sodium- and chloride-dependent glycine transporter 1Homo sapiens (human)106
Glutamate receptor ionotropic, NMDA 2A Rattus norvegicus (Norway rat)0.3253
Glutamate receptor ionotropic, NMDA 2BRattus norvegicus (Norway rat)0.3253
Glutamate receptor ionotropic, NMDA 2CRattus norvegicus (Norway rat)0.3253
Glutamate receptor ionotropic, NMDA 2DRattus norvegicus (Norway rat)0.3253
Glutamate receptor ionotropic, NMDA 3BRattus norvegicus (Norway rat)0.3253
Glutamate receptor ionotropic, NMDA 3ARattus norvegicus (Norway rat)0.3253
Sodium- and chloride-dependent glycine transporter 2Homo sapiens (human)128

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bockaert, J; Manahan-Vaughan, D; Pin, JP; Reiser, M; Reymann, KG; Riedel, G; Wilsch, V1
Reymann, KG; Riedel, G; Wagner, T; Wetzel, W1
Brown, RE; Reymann, KG1
Manahan-Vaughan, D; Reymann, KG1
Anderson, H; Blackburn-Munro, G; Dickinson, T; Fleetwood-Walker, SM; Johnson, MJ; Nakalembe, I; Young, MR1
Herrero, I; Manahan-Vaughan, D; Reymann, KG; Sánchez-Prieto, J1

Other Studies

6 other study(ies) available for azetidine-2,4-dicarboxylic acid and glycine

ArticleYear
Physiological and pharmacological profile of trans-azetidine-2,4-dicarboxylic acid: metabotropic glutamate receptor agonism and effects on long-term potentiation.
    Neuroscience, 1996, Volume: 72, Issue:4

    Topics: Animals; Azetidinecarboxylic Acid; Benzoates; Cells, Cultured; Colforsin; Cyclic AMP; Epithelial Cells; Epithelium; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; Hydrolysis; Inositol Phosphates; Kidney; Long-Term Potentiation; Male; N-Methylaspartate; Organ Culture Techniques; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Swine; Temperature; Transfection

1996
Open field behaviour in rats: role of metabotropic glutamate receptors.
    Neuroreport, 1995, Nov-27, Volume: 6, Issue:17

    Topics: Animals; Azetidinecarboxylic Acid; Behavior, Animal; Benzoates; Cyclic AMP; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Injections, Intraventricular; Male; Motor Activity; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Space Perception; Type C Phospholipases

1995
Class I metabotropic glutamate receptor agonists do not facilitate the induction of long-term potentiation in the dentate gyrus of the rat in vitro.
    Neuroscience letters, 1995, Dec-29, Volume: 202, Issue:1-2

    Topics: Animals; Azetidinecarboxylic Acid; Dentate Gyrus; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Long-Term Potentiation; Male; Picrotoxin; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Resorcinols

1995
Metabotropic glutamate receptor subtype agonists facilitate long-term potentiation within a distinct time window in the dentate gyrus in vivo.
    Neuroscience, 1996, Volume: 74, Issue:3

    Topics: Animals; Azetidinecarboxylic Acid; Dentate Gyrus; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Agonists; Glycine; Long-Term Potentiation; Male; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Resorcinols; Time Factors

1996
Antisense ablation of type I metabotropic glutamate receptor mGluR1 inhibits spinal nociceptive transmission.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1998, Dec-01, Volume: 18, Issue:23

    Topics: Animals; Antisense Elements (Genetics); Azetidinecarboxylic Acid; Behavior, Animal; Electrophysiology; Excitatory Amino Acid Agonists; Gene Deletion; Glycine; Male; Membrane Potentials; Mutagenesis; Nociceptors; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; Spinal Cord; Synaptic Transmission

1998
Presynaptic group 1 metabotropic glutamate receptors may contribute to the expression of long-term potentiation in the hippocampal CA1 region.
    Neuroscience, 1999, Volume: 94, Issue:1

    Topics: Animals; Azetidinecarboxylic Acid; Calcium; Cycloleucine; Dicarboxylic Acids; Diglycerides; Electric Stimulation; Electroencephalography; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Glycine; Hippocampus; Long-Term Potentiation; Male; Neuroprotective Agents; Neurotransmitter Uptake Inhibitors; Presynaptic Terminals; Pyrrolidines; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Resorcinols; Synaptosomes

1999