azelastine has been researched along with ketotifen in 44 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (38.64) | 18.7374 |
| 1990's | 17 (38.64) | 18.2507 |
| 2000's | 6 (13.64) | 29.6817 |
| 2010's | 3 (6.82) | 24.3611 |
| 2020's | 1 (2.27) | 2.80 |
| Authors | Studies |
|---|---|
| Augert, G; Cottin, M; Demonchaux, P; Dupassieux, P; Jasserand, D; Lenoir, P; Paris, D; Peck, MJ | 1 |
| Hai, K; Kamii, K; Kiriyama, H; Matsumoto, K; Nagura, T; Okano, K; Shiratori, Y; Takada, H; Tanaka, M | 1 |
| De Vos, C | 1 |
| Umeki, S | 2 |
| Yano, S | 1 |
| Ishizuka, T; Kobayashi, S; Kurosawa, M; Nakano, M | 1 |
| Holgate, ST; Lai, CK; Lau, CK; Ollier, S | 1 |
| Arimura, A; Inagaki, N; Koda, A; Miura, T; Mori, H; Nagai, H; Sakamoto, O | 1 |
| Nakagawa, T | 1 |
| Kanai, Y; Misawa, M | 1 |
| Chand, N; Diamantis, W; Pillar, J; Sofia, RD | 2 |
| Baba, M | 1 |
| Kuroiwa, H; Tomioka, S | 1 |
| Kamikawa, Y | 1 |
| Hoshino, K; Kawasaki, A; Mizushima, Y; Yano, S | 1 |
| Hayakawa, T; Ishibashi, T; Kato, K; Nishihira, J; Suzuki, K | 1 |
| Hara, M; Koya, N; Moroi, T; Nagata, K; Suzuki, S; Tateno, A | 1 |
| Drzewiecki, G; Ferriola, P; Middleton, E; Sofia, RD | 1 |
| Kobayashi, S; Kurosawa, M; Okayama, Y | 1 |
| Magnussen, H | 1 |
| Nakamura, T; Nishizawa, Y; Sato, T; Yamato, C | 1 |
| Achterrath-Tuckermann, U; Luck, W; Peskar, BA; Simmet, T; Szelenyi, I | 1 |
| Chand, N; Diamantis, W; Nolan, K; Perhach, JL; Sofia, RD | 1 |
| Kai, H; Katayama, K; Katayama, S; Sakuma, Y; Tanaka, I; Tsunoda, H | 1 |
| Chand, N; Diamantis, W; Harrison, JE; Rooney, SM; Sofia, RD | 1 |
| Chand, N; Diamantis, W; Perhach, JL; Pillar, J; Sofia, RD | 1 |
| Adachi, M; Asano, K; Konno, S; Okamoto, K | 1 |
| Kamei, C; Nakamura, S; Tasaka, K | 1 |
| Hai, K; Kawase, T; Kiriyama, H; Komatsu, Y; Matsumura, M; Mawet, E; Niwa, Y; Shiina, S; Shiratori, Y; Takada, H | 1 |
| Naclerio, RM | 1 |
| Fujimura, M | 1 |
| Kakiuchi, M; Kamiyama, K; Kato, H; Morikawa, K; Ohara, N; Ohashi, T; Tanaka, K | 1 |
| Blondin, C; Cholley, B; Goldschmidt, P; Haeffner-Cavaillon, N | 1 |
| Beauregard, C; Gamache, D; Roberts, L; Stephens, D; Yanni, J | 1 |
| Montero, JA; Pastor, S; Rodriguez, AE; Ruiz-Moreno, JM; Sanchis-Merino, ME | 1 |
| Gomes, P; Ousler, GW; Torkildsen, GL | 1 |
| Kim, N; Lee, JE; Lee, JS; Oum, BS | 1 |
| Bonini, S; Lambiase, A; Micera, A | 1 |
| Asano, K; Furuta, A; Hirano, K; Shoji, N; Suzaki, H | 1 |
| Andrioli, WJ; Bastos, JK; Chagas-Paula, DA; Furtado, NA; Jorge, JA; Naal, RM; Oliveira, RB; Pupo, MT; Santos, MS; Silva, CH; Silva, VB | 1 |
| Ben-Eli, H; Solomon, A | 1 |
| Baek, SY; Kim, HI; Kim, JH; Kim, YK; Shin, DW; Woo, IS | 1 |
4 review(s) available for azelastine and ketotifen
| Article | Year |
|---|---|
Pharmacological treatment of allergies.
Topics: Animals; Cetirizine; Drug Evaluation; Drug Evaluation, Preclinical; Guinea Pigs; Histamine H1 Antagonists; Humans; Hypersensitivity; Ketotifen; Papio; Phthalazines | 1992 |
[Inhibitor of chemical mediator release].
Topics: Asthma; Clinical Trials as Topic; Depression, Chemical; Double-Blind Method; Histamine H1 Antagonists; Humans; Inflammation Mediators; Ketotifen; Mast Cells; ortho-Aminobenzoates; Phthalazines; Terfenadine | 1996 |
Multiple action agents and the eye: do they really stabilize mast cells?
Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acid; Conjunctivitis, Allergic; Cytokines; Dibenzazepines; Dibenzoxepins; Histamine; Histamine Antagonists; Humans; Imidazoles; Immunity, Innate; Ketotifen; Mast Cells; Olopatadine Hydrochloride; Phthalazines | 2009 |
Topical antihistamines, mast cell stabilizers, and dual-action agents in ocular allergy: current trends.
Topics: Administration, Ophthalmic; Anti-Allergic Agents; Benzazepines; Conjunctivitis, Allergic; Cromolyn Sodium; Dibenzazepines; Histamine Antagonists; Humans; Hyperemia; Imidazoles; Ketotifen; Nedocromil; Olopatadine Hydrochloride; Phthalazines; Piperidines; Pruritus; Pyridines; Pyrimidinones | 2018 |
4 trial(s) available for azelastine and ketotifen
| Article | Year |
|---|---|
Effect of azelastine and ketotifen on the bronchial and skin responses to platelet-activating factor in humans.
Topics: Adult; Bronchoconstriction; Female; Forced Expiratory Volume; Histamine; Histamine H1 Antagonists; Humans; Ketotifen; Male; Middle Aged; Phthalazines; Platelet Activating Factor; Skin | 1991 |
The inhibitory effect of azelastine and ketotifen on histamine-induced bronchoconstriction in asthmatic patients.
Topics: Adult; Asthma; Bronchial Provocation Tests; Double-Blind Method; Female; Histamine; Histamine H1 Antagonists; Humans; Ketotifen; Male; Phthalazines; Pyridazines; Random Allocation | 1987 |
The effect of antihistamines on the immediate allergic response: a comparative review.
Topics: Capillary Permeability; Cetirizine; Cyproheptadine; Diphenhydramine; Double-Blind Method; Histamine H1 Antagonists; Humans; Ketotifen; Mast Cells; Peptide Hydrolases; Phthalazines; Rhinitis, Allergic, Seasonal; Sneezing; Terfenadine | 1993 |
Ocular comfort and drying effects of three topical antihistamine/mast cell stabilizers in adults with allergic conjunctivitis: a randomized, double-masked crossover study.
Topics: Adult; Conjunctivitis, Allergic; Cross-Over Studies; Dibenzazepines; Double-Blind Method; Female; Histamine H1 Antagonists; Humans; Imidazoles; Ketotifen; Male; Mast Cells; Ophthalmic Solutions; Phthalazines; Xerophthalmia | 2008 |
36 other study(ies) available for azelastine and ketotifen
| Article | Year |
|---|---|
Synthesis, structure-activity relationships, and pharmacological evaluation of pyrrolo[3,2,1-ij]quinoline derivatives: potent histamine and platelet activating factor antagonism and 5-lipoxygenase inhibitory properties. Potential therapeutic application i
Topics: Animals; Asthma; Female; Guinea Pigs; Histamine Antagonists; In Vitro Techniques; Lipoxygenase Inhibitors; Male; Platelet Activating Factor; Platelet Aggregation Inhibitors; Quinolines; Rabbits; Rats; Rats, Sprague-Dawley; Respiratory Function Tests; Skin Tests; Structure-Activity Relationship | 1995 |
Mechanism of accumulation of macrophages in galactosamine-induced liver injury: effect of lipoxygenase inhibitors on chemotaxis of spleen cells.
Topics: Animals; Benzoquinones; Cell Movement; Cells, Cultured; Chemotactic Factors; Chemotaxis; Culture Media, Conditioned; Galactosamine; Ketotifen; Lipoxygenase Inhibitors; Liver; Macrophages; Male; Mice; Phthalazines; Spleen | 1992 |
Effects of anti-allergic drugs on human neutrophil superoxide-generating NADPH oxidase.
Topics: Cell-Free System; Dose-Response Relationship, Drug; Histamine H1 Antagonists; Humans; Immunosuppressive Agents; Ketotifen; Kinetics; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; ortho-Aminobenzoates; Phthalazines; Piperazines; Pyridines; Quinolones; Structure-Activity Relationship | 1992 |
[Drug therapy of asthma by antiallergic agents].
Topics: Asthma; Cromolyn Sodium; Histamine Antagonists; Humans; Ketotifen; ortho-Aminobenzoates; Phthalazines; Platelet Activating Factor; SRS-A | 1992 |
Effects of antiallergic drugs on superoxide anion generation from activated human alveolar macrophages measured by chemiluminescence method.
Topics: Bronchoalveolar Lavage Fluid; Cromolyn Sodium; Histamine Antagonists; Histamine H2 Antagonists; Humans; Imidazoles; In Vitro Techniques; Ketotifen; Luminescent Measurements; Macrophages; Oxygen Consumption; Phthalazines; Pulmonary Alveoli; Pyrazines; Superoxide Dismutase; Superoxides | 1991 |
[Biochemical study on anti-inflammatory action of anti-allergic drugs--with regard to NADPH oxidase].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Histamine H1 Antagonists; Humans; Ketotifen; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Phthalazines; Piperazines | 1991 |
A method for evaluating anti-allergic drugs by simultaneously induced passive cutaneous anaphylaxis and mediator cutaneous reactions.
Topics: Albuterol; Animals; Diphenhydramine; Dose-Response Relationship, Drug; Female; Histamine H1 Antagonists; Isoproterenol; Ketotifen; Male; ortho-Aminobenzoates; Passive Cutaneous Anaphylaxis; Phenothiazines; Phthalazines; Rats; Rats, Inbred Strains; Skin Tests; Theophylline | 1990 |
[Chemical mediators and anti-mediator drugs].
Topics: Asthma; Chemotactic Factors, Eosinophil; Cromolyn Sodium; Cytokines; Depression, Chemical; Histamine; Humans; Hypersensitivity; Ketotifen; Mast Cells; ortho-Aminobenzoates; Phthalazines; SRS-A | 1991 |
Effect of the new antiallergic drug epinastine on chemical mediator induced bronchoconstrictions in guinea pigs.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Bradykinin; Bronchoconstriction; Dibenzazepines; Guinea Pigs; Histamine; Histamine H1 Antagonists; Imidazoles; Ketotifen; Male; Neurokinin A; Phthalazines; Piperazines; Prostaglandin D2; Prostaglandin Endoperoxides, Synthetic; SRS-A; Substance P | 1991 |
Inhibition of allergic histamine release by azelastine and selected antiallergic drugs from rabbit leukocytes.
Topics: Animals; Cromolyn Sodium; Diphenhydramine; Histamine H1 Antagonists; Histamine Release; In Vitro Techniques; Ketotifen; Leukocytes; Male; Phthalazines; Pyridazines; Rabbits; Theophylline; Time Factors | 1985 |
Inhibition of IgE-mediated allergic histamine release from rat peritoneal mast cells by azelastine and selected antiallergic drugs.
Topics: Animals; Astemizole; Benzimidazoles; Diphenhydramine; Histamine Release; Hypersensitivity; Immunoglobulin E; Ketotifen; Male; Mast Cells; Ovalbumin; Phosphatidylserines; Phthalazines; Pyridazines; Rats; Rats, Inbred Strains; Theophylline | 1985 |
[Progress of therapeutic agents for asthma--2. Prophylactic anti-asthmatic agents].
Topics: Administration, Inhalation; Administration, Oral; Animals; Asthma; Child, Preschool; Cromolyn Sodium; Guinea Pigs; Histamine H1 Antagonists; Humans; Ketotifen; ortho-Aminobenzoates; Phthalazines; Piperazines; Rats | 1987 |
[Therapeutic aspects of intractable asthma].
Topics: Adult; Aged; Asthma; Cromolyn Sodium; Female; Humans; Ketotifen; Male; Middle Aged; ortho-Aminobenzoates; Phthalazines; Terbutaline; Theophylline | 1988 |
Inhibitory effect of anti-allergic drugs on cholinergic and non-cholinergic neurotransmissions of guinea pig bronchial muscle in vitro.
Topics: Acetylcholine; Animals; Bronchi; Cholinergic Fibers; Cromolyn Sodium; Electric Stimulation; Guinea Pigs; Histamine H1 Antagonists; Ketotifen; Male; Muscle Contraction; Muscle, Smooth; ortho-Aminobenzoates; Phthalazines; Synaptic Transmission | 1989 |
[Improvement of airway hyperreactivity in bronchial asthma patients with short disease duration treated with anti-allergic agents].
Topics: Adult; Asthma; Bronchi; Cromolyn Sodium; Drug Therapy, Combination; Female; Histamine; Humans; Ketotifen; Male; Middle Aged; ortho-Aminobenzoates; Phthalazines; Time Factors | 1989 |
Effect of azelastine on leukotriene synthesis in murine peritoneal cells and on thromboxane synthesis in human platelets.
Topics: Animals; Blood Platelets; Calcimycin; Dose-Response Relationship, Drug; Epoxide Hydrolases; Glutathione Transferase; Hydroxyeicosatetraenoic Acids; Ketotifen; Leukotrienes; Lipoxygenase; Mice; ortho-Aminobenzoates; Peritoneal Cavity; Phospholipases A; Phospholipases A2; Phthalazines; Piperazines; Pyridazines; Thromboxanes | 1989 |
[The investigation of asthmatic children by multiple factor analysis. III. The changes in allergic factors selected by multiple factor analysis in 3 anti-allergic during treated groups over one year].
Topics: Adolescent; Asthma; Child; Child, Preschool; Eosinophils; Female; Histamine H1 Antagonists; Humans; Immunoglobulin G; Ketotifen; Leukocyte Count; Male; Multivariate Analysis; ortho-Aminobenzoates; Phthalazines; Prognosis; Pyridazines; Radioallergosorbent Test | 1989 |
The effect of azelastine and some other antiasthmatic and antiallergic drugs on calmodulin and protein kinase C.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Brain; Calcium; Calmodulin; Fluorescent Dyes; Histamine H1 Antagonists; Ketotifen; Phosphodiesterase Inhibitors; Phthalazines; Protein Kinase C; Pyridazines; Rats; Serum Albumin, Bovine; Spectrometry, Fluorescence; Sulfonamides | 1989 |
Inhibitory effect of adenine nucleotides and anti-allergic drugs on phosphorylation of phosphatidylinositol in rat mast cell granules.
Topics: 1-Phosphatidylinositol 4-Kinase; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Cromolyn Sodium; Cytoplasmic Granules; Histamine H1 Antagonists; Ketotifen; Mast Cells; Phosphatidylinositols; Phosphorylation; Phosphotransferases; Phthalazines; Rats; Theophylline | 1989 |
Effect of azelastine on the intracellular Ca2+ mobilization in guinea pig peritoneal macrophages.
Topics: Animals; Calcium; Cells, Cultured; Dinoprostone; Guinea Pigs; Histamine H1 Antagonists; Ketotifen; Macrophages; Male; N-Formylmethionine Leucyl-Phenylalanine; Peritoneal Cavity; Phthalazines; Platelet Activating Factor; Prostaglandins E; Pyridazines | 1988 |
Inhibition of cysteinyl-leukotriene production by azelastine and its biological significance.
Topics: Animals; Antigens; Arachidonic Acid; Arachidonic Acids; Bronchi; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Indomethacin; Ketotifen; Leukotriene E4; Male; Masoprocol; Muscle Contraction; Ovalbumin; Phthalazines; Pyridazines; SRS-A; Thromboxane B2; Trachea | 1988 |
Inhibition of leukotriene (SRS-A)-mediated acute lung anaphylaxis by azelastine in guinea pigs.
Topics: Anaphylaxis; Animals; Atropine; Chromones; Cromolyn Sodium; Guinea Pigs; Indomethacin; Ketotifen; Male; Methysergide; Phthalazines; Pyridazines; Pyrilamine; SRS-A | 1986 |
Effect of azelastine on the release and action of leukotriene C4 and D4.
Topics: Animals; Arachidonate 5-Lipoxygenase; Chlorpheniramine; Guinea Pigs; Ileum; In Vitro Techniques; Ketotifen; Lung; Phthalazines; Pyridazines; SRS-A | 1987 |
Inhibition of passive cutaneous anaphylaxis (PCA) by azelastine: dissociation of its antiallergic activities from antihistaminic and antiserotonin properties.
Topics: Animals; Antigens; Astemizole; Benzimidazoles; Histamine Antagonists; Hypersensitivity; Ketotifen; Male; Methysergide; Passive Cutaneous Anaphylaxis; Phthalazines; Pyridazines; Rats; Rats, Inbred Strains; Serotonin Antagonists; Time Factors | 1985 |
Inhibition of calcium ionophore (A23187)-stimulated histamine release from rat peritoneal mast cells by azelastine: implications for its mode of action.
Topics: Animals; Ascitic Fluid; Calcimycin; Calcium; Diphenhydramine; Histamine H1 Antagonists; Histamine Release; Ketotifen; Male; Mast Cells; Phthalazines; Pyridazines; Rats; Rats, Inbred Strains | 1983 |
Inhibition of cytokine production from human peripheral blood leukocytes by anti-allergic agents in vitro.
Topics: Cells, Cultured; Concanavalin A; Cromolyn Sodium; Cytokines; Enzyme-Linked Immunosorbent Assay; Histamine H1 Antagonists; Humans; Interleukin-2; Interleukin-3; Interleukin-4; Interleukin-5; Ketotifen; Lymphocyte Activation; Phthalazines; Piperazines; T-Lymphocytes | 1994 |
Inhibitory effect of epinastine on bronchoconstriction induced by histamine, platelet activating factor and serotonin in guinea pigs and rats.
Topics: Airway Resistance; Animals; Antigen-Antibody Reactions; Bronchoconstriction; Dibenzazepines; Guinea Pigs; Histamine H1 Antagonists; Imidazoles; In Vitro Techniques; Ketotifen; Male; Phthalazines; Platelet Activating Factor; Rats; Rats, Wistar; Serotonin Antagonists | 1994 |
Effect of anti-allergic agents on chemotaxis of neutrophils by stimulation of chemotactic factor released from hepatocytes exposed to ethanol.
Topics: Adult; Animals; Antibodies; Cells, Cultured; Chemokines; Chemotactic Factors; Chemotaxis, Leukocyte; Culture Media, Conditioned; Cytokines; Ethanol; Histamine H1 Antagonists; Humans; Hypersensitivity; Ketotifen; Liver; Neutrophils; Phthalazines; Prednisolone; Rats; Rats, Sprague-Dawley | 1994 |
Central nervous system effects of the novel antiallergic agent HSR-609 and typical antiallergic agents using behavioral and electroencephalographic analyses in dogs.
Topics: Animals; Anti-Allergic Agents; Behavior, Animal; Benzoxepins; Cyproheptadine; Dogs; Electroencephalography; Female; Histamine H1 Antagonists; Ketotifen; Male; Phthalazines; Piperazines; Pyridines; Terfenadine | 1998 |
[In vitro effects of antiallergic eyedrops on complement activation induced by particulate matter].
Topics: Air Pollutants; Anti-Allergic Agents; Benzalkonium Compounds; Benzimidazoles; Complement Activation; Conjunctivitis; Cosmetics; Dibenzoxepins; Dipeptides; Drug Evaluation; Dust; Humans; In Vitro Techniques; Ketotifen; Nedocromil; Olopatadine Hydrochloride; Ophthalmic Solutions; Oxamic Acid; Phthalazines; Piperidines; Pollen; Silicon Dioxide; Zymosan | 2003 |
Duration of action of topical antiallergy drugs in a Guinea pig model of histamine-induced conjunctival vascular permeability.
Topics: Administration, Topical; Animals; Anti-Allergic Agents; Capillary Permeability; Conjunctiva; Delayed-Action Preparations; Dibenzazepines; Dibenzoxepins; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Histamine H1 Antagonists; Imidazoles; Ketotifen; Male; Olopatadine Hydrochloride; Ophthalmic Solutions; Phthalazines | 2007 |
Comparative efficacy of topical antihistamines in an animal model of early phase allergic conjunctivitis.
Topics: Animals; Anti-Allergic Agents; Benzimidazoles; Coloring Agents; Conjunctivitis, Allergic; Dibenzoxepins; Dipeptides; Disease Models, Animal; Drug Evaluation, Preclinical; Evans Blue; Guinea Pigs; Histamine H1 Antagonists; Ketotifen; Male; Olopatadine Hydrochloride; Ophthalmic Solutions; Phthalazines; Severity of Illness Index; Treatment Outcome | 2008 |
Comparison of the conjunctival toxicity of topical ocular antiallergic agents.
Topics: Animals; Anti-Allergic Agents; Cells, Cultured; Conjunctiva; Dibenzoxepins; Hydrogen-Ion Concentration; Ketotifen; L-Lactate Dehydrogenase; Microscopy, Electron; Microscopy, Phase-Contrast; Olopatadine Hydrochloride; Phthalazines; Rabbits | 2008 |
Effect of histamine H1 receptor antagonists on TARC/CCL17 and MDC/CCL22 production from CD14+ cells induced by antigenic stimulation in vitro.
Topics: Adult; Antigens, Plant; Cell Proliferation; Chemokine CCL17; Chemokine CCL22; Chlorpheniramine; Extracellular Signal-Regulated MAP Kinases; GATA1 Transcription Factor; Gene Expression; Histamine; Histamine H1 Antagonists; Humans; Ketotifen; Leukocytes, Mononuclear; Lipopolysaccharide Receptors; Macrophages; Male; Middle Aged; NF-kappa B; Phosphorylation; Phthalazines; Piperazines; Plant Proteins; Rhinitis, Allergic, Seasonal; Signal Transduction; Terfenadine; Tuberculin; Young Adult | 2011 |
Δ-lactam derivative from thermophilic soil fungus exhibits in vitro anti-allergic activity.
Topics: Animals; Anti-Allergic Agents; Ascomycota; beta-N-Acetylhexosaminidases; Cell Degranulation; Cell Line, Tumor; Cell Survival; Computer Simulation; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Inhibitory Concentration 50; Ketotifen; Lactams; Magnetic Resonance Spectroscopy; Molecular Structure; Phthalazines; Pyridones; Rats; Soil Microbiology | 2012 |
Development and validation of a simultaneous analytical method for non-steroidal therapeutic compounds in cosmetics using liquid chromatography-tandem mass spectrometry.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Bufexamac; Chlorpheniramine; Chromatography, High Pressure Liquid; Clotrimazole; Cosmetics; Doxepin; Fusidic Acid; Ketotifen; ortho-Aminobenzoates; Phthalazines; Tacrolimus; Tandem Mass Spectrometry | 2021 |