azelastine has been researched along with diphenhydramine in 20 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (30.00) | 18.7374 |
| 1990's | 7 (35.00) | 18.2507 |
| 2000's | 4 (20.00) | 29.6817 |
| 2010's | 3 (15.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Carrupt, PA; Jolliet, P; Morin, C; Morin, D; Pagliara, A; Rihoux, JP; Testa, B; Tillement, JP; Urien, S | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 2 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chang, G; Di, L; Huang, Y; Lin, Z; Liston, TE; Scott, DO; Troutman, MD; Umland, JP | 1 |
| Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Arimura, A; Inagaki, N; Koda, A; Miura, T; Mori, H; Nagai, H; Sakamoto, O | 1 |
| Hasegawa, S; Hirata, F; Ishii, Y; Ninomiya, H; Nomura, A; Ohse, H; Saotome, M; Uchida, Y | 1 |
| Chand, N; Diamantis, W; Pillar, J; Sofia, RD | 2 |
| Fukuda, T; Makino, S; Motojima, S; Ohashi, Y; Otsuka, T | 1 |
| Igarashi, T; Murakami, M; Shoji, T; Yamanaka, T | 1 |
| Fukuda, T; Makino, S; Motojima, S | 1 |
| Chand, N; Diamantis, W; Perhach, JL; Pillar, J; Sofia, RD | 1 |
| Naclerio, RM | 1 |
| Chand, N; Diamantis, W; Harrison, JE; Rooney, S; Sofia, RD | 1 |
| Panizzon, KL; Wallis, RA | 1 |
| Kurokawa, K; Shichinohe, K; Shimizu, M | 1 |
2 trial(s) available for azelastine and diphenhydramine
| Article | Year |
|---|---|
Effects of azelastine on allergen- and exercise-induced asthma.
Topics: Adolescent; Adult; Allergens; Asthma; Asthma, Exercise-Induced; Bronchial Provocation Tests; Clinical Trials as Topic; Diphenhydramine; Female; Forced Expiratory Volume; Humans; Male; Middle Aged; Phthalazines; Pyridazines | 1985 |
The effect of antihistamines on the immediate allergic response: a comparative review.
Topics: Capillary Permeability; Cetirizine; Cyproheptadine; Diphenhydramine; Double-Blind Method; Histamine H1 Antagonists; Humans; Ketotifen; Mast Cells; Peptide Hydrolases; Phthalazines; Rhinitis, Allergic, Seasonal; Sneezing; Terfenadine | 1993 |
18 other study(ies) available for azelastine and diphenhydramine
| Article | Year |
|---|---|
Molecular properties and pharmacokinetic behavior of cetirizine, a zwitterionic H1-receptor antagonist.
Topics: Alkanes; Animals; Biological Transport; Blood Proteins; Brain; Cetirizine; Histamine H1 Antagonists; Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydroxyzine; Isomerism; Models, Molecular; Molecular Conformation; Octanols; Rats; Water | 1998 |
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding | 2002 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Species independence in brain tissue binding using brain homogenates.
Topics: Animals; Brain; Dogs; Guinea Pigs; Humans; Macaca fascicularis; Mice; Rats; Species Specificity | 2011 |
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment.
Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers | 2012 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
A method for evaluating anti-allergic drugs by simultaneously induced passive cutaneous anaphylaxis and mediator cutaneous reactions.
Topics: Albuterol; Animals; Diphenhydramine; Dose-Response Relationship, Drug; Female; Histamine H1 Antagonists; Isoproterenol; Ketotifen; Male; ortho-Aminobenzoates; Passive Cutaneous Anaphylaxis; Phenothiazines; Phthalazines; Rats; Rats, Inbred Strains; Skin Tests; Theophylline | 1990 |
Multiple mechanisms of bronchoconstrictive responses to endothelin-1.
Topics: Animals; Bronchoconstriction; Chromones; Diphenhydramine; Drug Interactions; Endothelins; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Indomethacin; Male; Phthalazines; SRS-A | 1991 |
Inhibition of allergic histamine release by azelastine and selected antiallergic drugs from rabbit leukocytes.
Topics: Animals; Cromolyn Sodium; Diphenhydramine; Histamine H1 Antagonists; Histamine Release; In Vitro Techniques; Ketotifen; Leukocytes; Male; Phthalazines; Pyridazines; Rabbits; Theophylline; Time Factors | 1985 |
Inhibition of IgE-mediated allergic histamine release from rat peritoneal mast cells by azelastine and selected antiallergic drugs.
Topics: Animals; Astemizole; Benzimidazoles; Diphenhydramine; Histamine Release; Hypersensitivity; Immunoglobulin E; Ketotifen; Male; Mast Cells; Ovalbumin; Phosphatidylserines; Phthalazines; Pyridazines; Rats; Rats, Inbred Strains; Theophylline | 1985 |
Effects of azelastine hydrochloride, a new antiallergic drug, on the gastrointestinal tract.
Topics: Animals; Bile; Clemastine; Digestive System; Diphenhydramine; Gastrointestinal Motility; Histamine H1 Antagonists; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Pancreatic Juice; Phthalazines; Pyridazines; Rats | 1981 |
[Comparison of suppressive effects of inhibitor of IgE mediated chemical mediator release and H1-blocker on exercise induced asthma (author's transl)].
Topics: Adult; Asthma; Asthma, Exercise-Induced; Diphenhydramine; Female; Heart Rate; Histamine H1 Antagonists; Humans; Male; Middle Aged; Phthalazines; Pyridazines | 1982 |
Inhibition of calcium ionophore (A23187)-stimulated histamine release from rat peritoneal mast cells by azelastine: implications for its mode of action.
Topics: Animals; Ascitic Fluid; Calcimycin; Calcium; Diphenhydramine; Histamine H1 Antagonists; Histamine Release; Ketotifen; Male; Mast Cells; Phthalazines; Pyridazines; Rats; Rats, Inbred Strains | 1983 |
Mucolytic activity of azelastine in mice and rats.
Topics: Acetylcysteine; Administration, Oral; Albuterol; Animals; Bromhexine; Carbocysteine; Diphenhydramine; Expectorants; Fluorescein; Fluoresceins; Histamine H1 Antagonists; Male; Mice; Phenolsulfonphthalein; Phthalazines; Potassium Iodide; Rats; Terbutaline; Trachea | 1993 |
Protection from hypoxic and N-methyl-D-aspartate injury with azelastine, a leukotriene inhibitor.
Topics: Animals; Diphenhydramine; Electrophysiology; Hippocampus; Hypoxia; In Vitro Techniques; Leukotriene C4; Lipoxygenase Inhibitors; Male; Membrane Potentials; N-Methylaspartate; Phthalazines; Rats; Rats, Sprague-Dawley; Receptors, Histamine H1 | 1993 |
Effect of M-711 on experimental skin reactions induced by chemical mediators in rats.
Topics: Animals; Anti-Allergic Agents; Dermatitis, Allergic Contact; Dexamethasone; Diphenhydramine; Drugs, Chinese Herbal; Leukotriene C4; Male; Phthalazines; Phytotherapy; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Skin Tests | 1996 |