azelastine has been researched along with desmethylazelastine in 7 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 3 (42.86) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Katoh, M; Nakajima, M; Yamazaki, H; Yokoi, T | 1 |
| Brooks, S; Kulkarni, A; Miller, L; Richards, IS; Solomon, D; Sperelakis, N | 1 |
| Hartman, CA; Kucharczyk, N; Pivonka, J; Segelman, FH; Segl, WE; Sofia, RD | 1 |
| Adusumalli, VE; Chand, N; Diamantis, W; Kucharczyk, N; Langevin, CN; Nolan, K; Pivonka, J; Sofia, RD; Wichmann, JK; Wong, KK | 1 |
| Adusumalli, VE; Kucharczyk, N; Sofia, RD; Wichmann, JK; Wong, KK | 1 |
| Nakajima, M; Nakamura, S; Shimada, N; Tane, K; Yamazaki, H; Yokoi, T | 1 |
| Shum, L; Zha, W | 1 |
7 other study(ies) available for azelastine and desmethylazelastine
| Article | Year |
|---|---|
Inhibitory effects of CYP3A4 substrates and their metabolites on P-glycoprotein-mediated transport.
Topics: Amiodarone; Animals; Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Calcium Channel Blockers; Cells, Cultured; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Daunorubicin; Digoxin; Enzyme Inhibitors; GABA Modulators; Gonadal Steroid Hormones; Humans; LLC-PK1 Cells; Midazolam; Mixed Function Oxygenases; Nifedipine; Phthalazines; Swine; Testosterone | 2001 |
Azelastine and desmethylazelastine suppress acetylcholine-induced contraction and depolarization in human airway smooth muscle.
Topics: Acetylcholine; Electrophysiology; Histamine H1 Antagonists; Humans; In Vitro Techniques; Isometric Contraction; Membrane Potentials; Microelectrodes; Muscle Contraction; Muscle, Smooth; Phthalazines; Trachea | 1990 |
Determination of azelastine and desmethylazelastine in human plasma by high-performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Drug Interactions; Histamine H1 Antagonists; Humans; Phthalazines; Pyridazines; Spectrometry, Fluorescence | 1987 |
Pharmacodynamic and pharmacokinetic studies with azelastine in the guinea pig: evidence for preferential distribution into the lung.
Topics: Animals; Asthma; Guinea Pigs; Histamine H1 Antagonists; Hypersensitivity, Immediate; Lung; Phthalazines | 1993 |
Pharmacokinetics of the new antiasthma and antiallergy drug, azelastine, in pediatric and adult beagle dogs.
Topics: Animals; Biological Availability; Bronchodilator Agents; Chromatography, High Pressure Liquid; Dogs; Female; Half-Life; Histamine H1 Antagonists; Male; Phthalazines | 1993 |
Evaluation of approach to predict the contribution of multiple cytochrome P450s in drug metabolism using relative activity factor: effects of the differences in expression levels of NADPH-cytochrome P450 reductase and cytochrome b(5) in the expression sys
Topics: Animals; Baculoviridae; Biomarkers; Cytochrome P-450 Enzyme System; Cytochromes b5; Forecasting; Humans; Insecta; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Phthalazines; Recombinant Proteins | 2002 |
Simultaneous determination of azelastine and its major metabolite desmethylazelastine in human plasma using high performance liquid chromatography-tandem mass spectrometry.
Topics: Chromatography, High Pressure Liquid; Drug Stability; Humans; Least-Squares Analysis; Liquid-Liquid Extraction; Phthalazines; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry | 2012 |