azd9272 and fenobam

azd9272 has been researched along with fenobam* in 1 studies

Other Studies

1 other study(ies) available for azd9272 and fenobam

Article	Year
The pro-psychotic metabotropic glutamate receptor compounds fenobam and AZD9272 share binding sites with monoamine oxidase-B inhibitors in humans. Neuropharmacology, 2020, 01-01, Volume: 162 The metabotropic glutamate receptor 5 (mGluR5) ligands fenobam and AZD9272 have been reported to induce psychosis-like adverse events and to bind at unknown, non-GluR5-related, sites. Based on similarities of the regional binding patterns for [ Topics: Adult; Allosteric Regulation; Animals; Binding Sites; Brain; Carbon Radioisotopes; Female; Humans; Imidazoles; Macaca fascicularis; Male; Middle Aged; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Oxadiazoles; Oximes; Positron-Emission Tomography; Psychoses, Substance-Induced; Pyridines; Radiopharmaceuticals; Receptor, Metabotropic Glutamate 5; Selegiline; Young Adult	2020

Article

Year

The pro-psychotic metabotropic glutamate receptor compounds fenobam and AZD9272 share binding sites with monoamine oxidase-B inhibitors in humans.

Neuropharmacology, 2020, 01-01, Volume: 162

The metabotropic glutamate receptor 5 (mGluR5) ligands fenobam and AZD9272 have been reported to induce psychosis-like adverse events and to bind at unknown, non-GluR5-related, sites. Based on similarities of the regional binding patterns for [

Topics: Adult; Allosteric Regulation; Animals; Binding Sites; Brain; Carbon Radioisotopes; Female; Humans; Imidazoles; Macaca fascicularis; Male; Middle Aged; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Oxadiazoles; Oximes; Positron-Emission Tomography; Psychoses, Substance-Induced; Pyridines; Radiopharmaceuticals; Receptor, Metabotropic Glutamate 5; Selegiline; Young Adult

2020