Page last updated: 2024-09-05

azd2563 and oxazolidin-2-one

azd2563 has been researched along with oxazolidin-2-one in 26 studies

Compound Research Comparison

Studies (azd2563)	Trials (azd2563)	Recent Studies (post-2010) (azd2563)	Studies (oxazolidin-2-one)	Trials (oxazolidin-2-one)	Recent Studies (post-2010) (oxazolidin-2-one)
29	0	9	4,376	347	1,734

Research

Studies (26)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	19 (73.08)	29.6817
2010's	6 (23.08)	24.3611
2020's	1 (3.85)	2.80

Authors

Authors	Studies
Anderegg, TR; Biedenbach, DJ; Jones, RN	4
Anderegg, TR; Deshpande, LM; Jones, RN	1
Johnson, AP; Livermore, DM; Warner, M	1
Appelbaum, PC; Clark, CL; Jacobs, MR; Lin, G; Peric, M	1
Appelbaum, PC; Ednie, LM; Jacobs, MR	1
Johnson, AP	1
Fluit, AC; Milatovic, D; Schmitz, FJ; Verhoef, J	1
Baum, SE; Crawford, SA; Jorgensen, JH; McElmeel, ML; Whitney, CG	1
Eliopoulos, GM; Moellering, RC; Wennersten, CB	1
Fluit, AC; Milatovic, D; Schmitz, FJ	1
Anderegg, TR; Jones, RN	2
Johnson, AP; Livermore, DM; Malnick, H; Warner, M	1
Bowker, KE; Howe, RA; MacGowan, AP; Noel, AR; Walsh, TR; Wootton, M	1
Acton, DG; Betts, MJ; Dennis, M; Gravestock, MB; Hatter, G; McGregor, A; Swain, ML; Wilson, RG; Woods, L; Wookey, A	1
Clarke, J; Eastwood, M; Greenhalgh, JM; Sefton, C; Turner, PJ; Wookey, A	1
Jeong, BH; Koh, WJ; Kwon, YS	1
Balasubramanian, V; Cole, ST; Dhar, N; Marriner, G; Sala, C; Sambandamurthy, VK; Sharma, S; Vocat, A; Zhang, M	1
Balasubramanian, V; Hoffner, S; Perskvist, N; Rodrigues, C; Sambandamurthy, VK; Werngren, J; Wijkander, M	1
Balasubramanian, V; Bharath, S; Butler, SL; Deshpande, A; Gaonkar, S; Kumar, N; Mahesh, KN; Melnick, D; Reddy, J; Shandil, R; Solapure, S; Wright, L	1
Barry, CE; Chen, RY; Cho, SN; Coleman, MT; Dartois, V; Dodd, LE; Flynn, JL; Janssen, C; Kim, Y; Klein, E; Lee, M; Lin, PL; Maiello, P; Marriner, G; Scanga, C; Via, LE; Wang, J	1
Betoudji, F; Converse, PJ; Dartois, V; Li, SY; Mdluli, KE; Mendel, CM; Nuermberger, EL; Tasneen, R; Tyagi, S; Williams, K; Yang, T	1
Karkara, BB; Kumar, A; Panda, G	1

Reviews

3 review(s) available for azd2563 and oxazolidin-2-one

Article	Year
AZD-2563 AstraZeneca. Current opinion in investigational drugs (London, England : 2000), 2002, Volume: 3, Issue:6 Topics: Acetamides; Animals; Anti-Bacterial Agents; Disease Models, Animal; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Linezolid; Microbial Sensitivity Tests; Oxazolidinones; Structure-Activity Relationship	2002
Tuberculosis: clinical trials and new drug regimens. Current opinion in pulmonary medicine, 2014, Volume: 20, Issue:3 Topics: Acetamides; Adamantane; Antitubercular Agents; Clinical Trials as Topic; Diarylquinolines; Drug Administration Schedule; Drug Design; Ethylenediamines; Female; Fluoroquinolones; Humans; Levofloxacin; Linezolid; Male; Moxifloxacin; Nitroimidazoles; Oxazoles; Oxazolidinones; Spiro Compounds; Thiazines; Tuberculosis; Tuberculosis, Multidrug-Resistant	2014
Novel candidates in the clinical development pipeline for TB drug development and their synthetic approaches. Chemical biology & drug design, 2021, Volume: 98, Issue:5 Topics: Adamantane; Animals; Antitubercular Agents; DNA Gyrase; Drug Development; Enzyme Inhibitors; Humans; Isonicotinic Acids; Mycobacterium tuberculosis; Oxazolidinones; Piperidines; Pyrroles; Structure-Activity Relationship; Tuberculosis; Tuberculosis, Multidrug-Resistant; Uridine	2021

Other Studies

23 other study(ies) available for azd2563 and oxazolidin-2-one

Article	Year
In vitro evaluation of AZD2563, a new oxazolidinone, tested against unusual gram-positive species. Diagnostic microbiology and infectious disease, 2002, Volume: 42, Issue:2 Topics: Anti-Bacterial Agents; Gram-Positive Bacteria; Humans; Microbial Sensitivity Tests; Oxazolidinones	2002
In vitro evaluation of AZD2563, a new oxazolidinone, tested against beta-haemolytic and viridans group streptococci. The Journal of antimicrobial chemotherapy, 2002, Volume: 49, Issue:6 Topics: Drug Evaluation, Preclinical; Humans; Microbial Sensitivity Tests; Oxazolidinones; Streptococcus pyogenes; Viridans Streptococci	2002
AZD2563, a new oxazolidinone: bactericidal activity and synergy studies combined with gentamicin or vancomycin against staphylococci and streptococcal strains. Diagnostic microbiology and infectious disease, 2002, Volume: 43, Issue:1 Topics: Anti-Bacterial Agents; Drug Resistance, Multiple, Bacterial; Drug Synergism; Drug Therapy, Combination; Gentamicins; Microbial Sensitivity Tests; Oxazolidinones; Staphylococcus; Streptococcus; Time Factors; Vancomycin	2002
In vitro activity of a novel oxazolidinone, AZD2563, against randomly selected and multiresistant Gram-positive cocci. The Journal of antimicrobial chemotherapy, 2002, Volume: 50, Issue:1 Topics: Acetamides; Anti-Bacterial Agents; Coagulase; Drug Resistance, Multiple, Bacterial; Enterococcus faecalis; Enterococcus faecium; Gram-Positive Cocci; Humans; Linezolid; Microbial Sensitivity Tests; Oxazolidinones; Staphylococcus aureus; Streptococcus pneumoniae	2002
Antipneumococcal activity of AZD2563, a new oxazolidinone, compared with nine other agents. The Journal of antimicrobial chemotherapy, 2002, Volume: 50, Issue:1 Topics: Anti-Bacterial Agents; Drug Resistance, Bacterial; Humans; Microbial Sensitivity Tests; Oxazolidinones; Streptococcus pneumoniae	2002
Anti-anaerobic activity of AZD2563, a new oxazolidinone, compared with eight other agents. The Journal of antimicrobial chemotherapy, 2002, Volume: 50, Issue:1 Topics: Anti-Bacterial Agents; Bacteria, Anaerobic; Gram-Negative Anaerobic Bacteria; Gram-Positive Bacteria; Humans; Microbial Sensitivity Tests; Oxazolidinones	2002
In vitro evaluation of AZD2563, a novel oxazolidinone, against 603 recent staphylococcal isolates. Antimicrobial agents and chemotherapy, 2002, Volume: 46, Issue:8 Topics: Acetamides; Anti-Bacterial Agents; Drug Resistance, Microbial; Humans; Linezolid; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones; Staphylococcal Infections; Staphylococcus aureus	2002
In vitro activity of AZD2563, a novel oxazolidinone, against European Gram-positive cocci. The Journal of antimicrobial chemotherapy, 2002, Volume: 50, Issue:2 Topics: Anti-Bacterial Agents; Enterococcus faecalis; Enterococcus faecium; Gram-Positive Cocci; Humans; Microbial Sensitivity Tests; Oxazolidinones; Streptococcus	2002
Comparative activities of the oxazolidinone AZD2563 and linezolid against selected recent North American isolates of Streptococcus pneumoniae. Antimicrobial agents and chemotherapy, 2002, Volume: 46, Issue:9 Topics: Acetamides; Anti-Bacterial Agents; Drug Resistance, Microbial; Humans; Linezolid; Microbial Sensitivity Tests; North America; Oxazolidinones; Pneumococcal Infections; Streptococcus pneumoniae	2002
In vitro activity of the new oxazolidinone AZD2563 against Enterococci. Antimicrobial agents and chemotherapy, 2002, Volume: 46, Issue:10 Topics: Acetamides; Drug Resistance, Bacterial; Enterococcus; Humans; Linezolid; Microbial Sensitivity Tests; Oxazolidinones	2002
The presence of ermB in Streptococcus pneumoniae has no influence on AZD2563 MIC values. The Journal of antimicrobial chemotherapy, 2003, Volume: 51, Issue:1 Topics: Anti-Bacterial Agents; Drug Resistance, Bacterial; Humans; Methyltransferases; Microbial Sensitivity Tests; Oxazolidinones; Streptococcus pneumoniae	2003
Determination of disk diffusion and MIC quality control parameters for AZD2563, a novel long-acting oxazolidinone. Diagnostic microbiology and infectious disease, 2003, Volume: 45, Issue:1 Topics: Diffusion; Drug Resistance, Microbial; Enterococcus faecalis; Gram-Positive Bacteria; Humans; Microbial Sensitivity Tests; Oxazolidinones; Quality Control; Sensitivity and Specificity; Staphylococcus aureus; Streptococcus pneumoniae	2003
Activity of the oxazolidinones AZD2563 and linezolid against Corynebacterium jeikeium and other Corynebacterium spp. The Journal of antimicrobial chemotherapy, 2003, Volume: 51, Issue:3 Topics: Acetamides; Corynebacterium; Drug Resistance, Multiple, Bacterial; Humans; Linezolid; Oxazolidinones	2003
Validation of commercial dry-form broth microdilution panels for susceptibility testing of AZD2563, a new long-acting oxazolidinone. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2003, Volume: 9, Issue:6 Topics: Anti-Bacterial Agents; Drug Resistance, Bacterial; Gram-Positive Cocci; Oxazolidinones	2003
Activity of AZD2563, a novel oxazolidinone, against Staphylococcus aureus strains with reduced susceptibility to vancomycin or linezolid. Antimicrobial agents and chemotherapy, 2003, Volume: 47, Issue:11 Topics: Acetamides; Anti-Infective Agents; Drug Resistance, Bacterial; Humans; Linezolid; Microbial Sensitivity Tests; Oxazolidinones; Staphylococcal Infections; Staphylococcus aureus; Vancomycin Resistance	2003
New classes of antibacterial oxazolidinones with C-5, methylene O-linked heterocyclic side chains. Bioorganic & medicinal chemistry letters, 2003, Dec-01, Volume: 13, Issue:23 Topics: Animals; Anti-Bacterial Agents; Gram-Positive Bacteria; Heterocyclic Compounds; Hydrocarbons; Methane; Mice; Microbial Sensitivity Tests; Oxazolidinones; Rats; Staphylococcal Infections; Staphylococcus aureus; Structure-Activity Relationship	2003
Preliminary susceptibility testing guidelines for AZD2563, a long-acting oxazolidinone. International journal of antimicrobial agents, 2004, Volume: 23, Issue:1 Topics: Anti-Bacterial Agents; Gram-Positive Bacteria; Humans; Microbial Sensitivity Tests; Oxazolidinones; Staphylococcus aureus	2004
AZD2563, a novel oxazolidinone: definition of antibacterial spectrum, assessment of bactericidal potential and the impact of miscellaneous factors on activity in vitro. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2004, Volume: 10, Issue:3 Topics: Bacteria; Microbial Sensitivity Tests; Oxazolidinones	2004
In vitro and in vivo activities of three oxazolidinones against nonreplicating Mycobacterium tuberculosis. Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:6 Topics: Acetamides; Animals; Antitubercular Agents; Cells, Cultured; Colony Count, Microbial; Female; Hypoxia; Latent Tuberculosis; Linezolid; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Oxazolidinones	2014
In vitro activity of AZD5847 against geographically diverse clinical isolates of Mycobacterium tuberculosis. Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:7 Topics: Antitubercular Agents; Drug Resistance, Multiple, Bacterial; Extensively Drug-Resistant Tuberculosis; Humans; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Oxazolidinones; Tuberculosis, Pulmonary	2014
Pharmacokinetic and pharmacodynamic evaluation of AZD5847 in a mouse model of tuberculosis. Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:7 Topics: Animals; Area Under Curve; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Dosage Calculations; Drug Resistance, Multiple, Bacterial; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Oxazolidinones; Tuberculosis, Pulmonary	2014
PET/CT imaging reveals a therapeutic response to oxazolidinones in macaques and humans with tuberculosis. Science translational medicine, 2014, Dec-03, Volume: 6, Issue:265 Topics: Acetamides; Algorithms; Animals; Anti-Bacterial Agents; Extensively Drug-Resistant Tuberculosis; Fluorodeoxyglucose F18; Humans; Linezolid; Lymph Nodes; Macaca; Multimodal Imaging; Oxazolidinones; Positron-Emission Tomography; Stem Cells; Tomography, X-Ray Computed; Treatment Outcome	2014
Contribution of Oxazolidinones to the Efficacy of Novel Regimens Containing Bedaquiline and Pretomanid in a Mouse Model of Tuberculosis. Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:1 Topics: Animals; Antitubercular Agents; Bacterial Load; Diarylquinolines; Disease Models, Animal; Drug Administration Schedule; Drug Combinations; Drug Resistance, Multiple, Bacterial; Drug Synergism; Female; Linezolid; Lung; Mice; Mice, Inbred BALB C; Mycobacterium tuberculosis; Nitroimidazoles; Organophosphates; Oxazoles; Oxazolidinones; Pyrazinamide; Time Factors; Treatment Outcome; Tuberculosis, Pulmonary	2016