azd2563 has been researched along with linezolid in 14 studies
| Studies (azd2563) | Trials (azd2563) | Recent Studies (post-2010) (azd2563) | Studies (linezolid) | Trials (linezolid) | Recent Studies (post-2010) (linezolid) |
|---|---|---|---|---|---|
| 29 | 0 | 9 | 3,916 | 222 | 2,188 |
| Protein | Taxonomy | azd2563 (IC50) | linezolid (IC50) |
|---|---|---|---|
| Prostaglandin G/H synthase 1 | Homo sapiens (human) | 8.19 | |
| Amine oxidase [flavin-containing] B | Homo sapiens (human) | 2.1 | |
| Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | Homo sapiens (human) | 8.19 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 8 (57.14) | 29.6817 |
| 2010's | 6 (42.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Acton, DG; Betts, MJ; Dennis, M; Gravestock, MB; Hatter, G; McGregor, A; Swain, ML; Wilson, RG; Woods, L; Wookey, A | 1 |
| Baulard, AR; Crauste, C; Déprez, B; Flipo, M; Villemagne, B; Willand, N | 1 |
| Biava, M; Cocozza, M; Consalvi, S; Poce, G | 1 |
| Johnson, AP; Livermore, DM; Warner, M | 1 |
| Anderegg, TR; Biedenbach, DJ; Jones, RN | 1 |
| Johnson, AP | 1 |
| Baum, SE; Crawford, SA; Jorgensen, JH; McElmeel, ML; Whitney, CG | 1 |
| Eliopoulos, GM; Moellering, RC; Wennersten, CB | 1 |
| Johnson, AP; Livermore, DM; Malnick, H; Warner, M | 1 |
| Bowker, KE; Howe, RA; MacGowan, AP; Noel, AR; Walsh, TR; Wootton, M | 1 |
| Jeong, BH; Koh, WJ; Kwon, YS | 1 |
| Balasubramanian, V; Cole, ST; Dhar, N; Marriner, G; Sala, C; Sambandamurthy, VK; Sharma, S; Vocat, A; Zhang, M | 1 |
| Barry, CE; Chen, RY; Cho, SN; Coleman, MT; Dartois, V; Dodd, LE; Flynn, JL; Janssen, C; Kim, Y; Klein, E; Lee, M; Lin, PL; Maiello, P; Marriner, G; Scanga, C; Via, LE; Wang, J | 1 |
| Betoudji, F; Converse, PJ; Dartois, V; Li, SY; Mdluli, KE; Mendel, CM; Nuermberger, EL; Tasneen, R; Tyagi, S; Williams, K; Yang, T | 1 |
4 review(s) available for azd2563 and linezolid
| Article | Year |
|---|---|
Tuberculosis: the drug development pipeline at a glance.
Topics: Animals; Antitubercular Agents; Clinical Trials as Topic; Drug Discovery; Humans; Tuberculosis | 2012 |
SAR analysis of new anti-TB drugs currently in pre-clinical and clinical development.
Topics: Animals; Antitubercular Agents; Humans; Mycobacterium tuberculosis; Structure-Activity Relationship; Tuberculosis; Tuberculosis, Multidrug-Resistant | 2014 |
AZD-2563 AstraZeneca.
Topics: Acetamides; Animals; Anti-Bacterial Agents; Disease Models, Animal; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Linezolid; Microbial Sensitivity Tests; Oxazolidinones; Structure-Activity Relationship | 2002 |
Tuberculosis: clinical trials and new drug regimens.
Topics: Acetamides; Adamantane; Antitubercular Agents; Clinical Trials as Topic; Diarylquinolines; Drug Administration Schedule; Drug Design; Ethylenediamines; Female; Fluoroquinolones; Humans; Levofloxacin; Linezolid; Male; Moxifloxacin; Nitroimidazoles; Oxazoles; Oxazolidinones; Spiro Compounds; Thiazines; Tuberculosis; Tuberculosis, Multidrug-Resistant | 2014 |
10 other study(ies) available for azd2563 and linezolid
| Article | Year |
|---|---|
New classes of antibacterial oxazolidinones with C-5, methylene O-linked heterocyclic side chains.
Topics: Animals; Anti-Bacterial Agents; Gram-Positive Bacteria; Heterocyclic Compounds; Hydrocarbons; Methane; Mice; Microbial Sensitivity Tests; Oxazolidinones; Rats; Staphylococcal Infections; Staphylococcus aureus; Structure-Activity Relationship | 2003 |
In vitro activity of a novel oxazolidinone, AZD2563, against randomly selected and multiresistant Gram-positive cocci.
Topics: Acetamides; Anti-Bacterial Agents; Coagulase; Drug Resistance, Multiple, Bacterial; Enterococcus faecalis; Enterococcus faecium; Gram-Positive Cocci; Humans; Linezolid; Microbial Sensitivity Tests; Oxazolidinones; Staphylococcus aureus; Streptococcus pneumoniae | 2002 |
In vitro evaluation of AZD2563, a novel oxazolidinone, against 603 recent staphylococcal isolates.
Topics: Acetamides; Anti-Bacterial Agents; Drug Resistance, Microbial; Humans; Linezolid; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones; Staphylococcal Infections; Staphylococcus aureus | 2002 |
Comparative activities of the oxazolidinone AZD2563 and linezolid against selected recent North American isolates of Streptococcus pneumoniae.
Topics: Acetamides; Anti-Bacterial Agents; Drug Resistance, Microbial; Humans; Linezolid; Microbial Sensitivity Tests; North America; Oxazolidinones; Pneumococcal Infections; Streptococcus pneumoniae | 2002 |
In vitro activity of the new oxazolidinone AZD2563 against Enterococci.
Topics: Acetamides; Drug Resistance, Bacterial; Enterococcus; Humans; Linezolid; Microbial Sensitivity Tests; Oxazolidinones | 2002 |
Activity of the oxazolidinones AZD2563 and linezolid against Corynebacterium jeikeium and other Corynebacterium spp.
Topics: Acetamides; Corynebacterium; Drug Resistance, Multiple, Bacterial; Humans; Linezolid; Oxazolidinones | 2003 |
Activity of AZD2563, a novel oxazolidinone, against Staphylococcus aureus strains with reduced susceptibility to vancomycin or linezolid.
Topics: Acetamides; Anti-Infective Agents; Drug Resistance, Bacterial; Humans; Linezolid; Microbial Sensitivity Tests; Oxazolidinones; Staphylococcal Infections; Staphylococcus aureus; Vancomycin Resistance | 2003 |
In vitro and in vivo activities of three oxazolidinones against nonreplicating Mycobacterium tuberculosis.
Topics: Acetamides; Animals; Antitubercular Agents; Cells, Cultured; Colony Count, Microbial; Female; Hypoxia; Latent Tuberculosis; Linezolid; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Oxazolidinones | 2014 |
PET/CT imaging reveals a therapeutic response to oxazolidinones in macaques and humans with tuberculosis.
Topics: Acetamides; Algorithms; Animals; Anti-Bacterial Agents; Extensively Drug-Resistant Tuberculosis; Fluorodeoxyglucose F18; Humans; Linezolid; Lymph Nodes; Macaca; Multimodal Imaging; Oxazolidinones; Positron-Emission Tomography; Stem Cells; Tomography, X-Ray Computed; Treatment Outcome | 2014 |
Contribution of Oxazolidinones to the Efficacy of Novel Regimens Containing Bedaquiline and Pretomanid in a Mouse Model of Tuberculosis.
Topics: Animals; Antitubercular Agents; Bacterial Load; Diarylquinolines; Disease Models, Animal; Drug Administration Schedule; Drug Combinations; Drug Resistance, Multiple, Bacterial; Drug Synergism; Female; Linezolid; Lung; Mice; Mice, Inbred BALB C; Mycobacterium tuberculosis; Nitroimidazoles; Organophosphates; Oxazoles; Oxazolidinones; Pyrazinamide; Time Factors; Treatment Outcome; Tuberculosis, Pulmonary | 2016 |