Page last updated: 2024-08-17

azauridine and uridine

azauridine has been researched along with uridine in 36 studies

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-199034 (94.44)18.7374
1990's1 (2.78)18.2507
2000's0 (0.00)29.6817
2010's1 (2.78)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Katz, DJ; Townsend, LB; Wise, DS1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Cihák, A; Rada, B1
Gulen, S; Tremblay, GC1
Keppler, DO1
Hsiao, WL; Krooth, RS; Lam, GF1
Herrmann, B; Holstege, A; Keppler, DO1
Gröbner, W; Zöllner, N1
Cha, S; Janeway, CM1
Beránek, J; Hrebabecký, H1
Ralph, RK; Wojcik, SJ1
Davis, CW; Martin, HL; Saint Geme, JW1
Hashmi, S; Krooth, RS; May, SR; Miller, OJ1
DeLapp, NW; Karasek, MA1
Holstege, A; Keppler, D1
Anukarahanonta, T; Gerok, W; Holstege, A; Keppler, D; Pausch, J1
Cihák, A; Harrap, KR; Veselý, J1
Rada, B; Zemla, J1
Saenger, W1
Shinozuka, H1
Bagdasarova, IV; Chernetskiĭ, VP; Povolotskiĭ, IaL1
Katz, M; Koprowski, H; Lennette, EH; Leonard, LL; ter Meulen, V1
Hoogenraad, NJ; Kretchmer, N; Roux, JM1
Saenger, W; Schwalbe, CH1
Ito, K; Uchino, H1
Jelínek, R; Rychter, Z2
Elis, J; Jankú, I; Rasková, H1
Anukarahanonta, T; Holstege, A; Keppler, DO1
Beck, G; Giesen, EM; Holstege, A; Keppler, DO1
Anderson, LW; Cysyk, RL; Dietrick, DD; Karle, JM1
Belt, JA; Welch, AD1
Nemec, J; Panahi, J; Welch, AD1
Blesová, B; Novotný, L; Petrásová, R; Pískala, A; Vachálková, A1
LOGERFO, P; WILSON, DE1
Chabner, BA; Drake, JC; Fuller, RW; Hande, KR1

Reviews

2 review(s) available for azauridine and uridine

ArticleYear
[Disorders of human pyrimidine metabolism (author's transl)].
    MMW, Munchener medizinische Wochenschrift, 1975, Volume: 117, Issue:37

    Topics: Allopurinol; Azauridine; Chemical Phenomena; Chemistry; Cytidine; Folic Acid; Humans; Infant; Male; Ornithine Carbamoyltransferase; Orotic Acid; Phosphoribosyl Pyrophosphate; Purine-Pyrimidine Metabolism, Inborn Errors; Purines; Pyrimidine Nucleotides; Pyrimidines; Uridine

1975
Structure and function of nucleosides and nucleotides.
    Angewandte Chemie (International ed. in English), 1973, Volume: 12, Issue:8

    Topics: Adenosine; Azauridine; Base Sequence; Binding Sites; Dactinomycin; Drug Stability; Glycosides; Models, Chemical; Molecular Conformation; Nucleosides; Nucleotides; Pancreas; Ribonucleases; RNA, Transfer; Stereoisomerism; Structure-Activity Relationship; Thiouridine; Uridine; X-Ray Diffraction

1973

Other Studies

34 other study(ies) available for azauridine and uridine

ArticleYear
Synthesis of pyridazine analogues of the naturally occurring nucleosides cytidine, uridine, deoxycytidine, and deoxyuridine.
    Journal of medicinal chemistry, 1982, Volume: 25, Issue:7

    Topics: Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; Cytidine; Deoxycytidine; Deoxyuridine; Hydrolysis; In Vitro Techniques; Leukemia L1210; Magnetic Resonance Spectroscopy; Mice; Pyridazines; Pyrimidine Nucleosides; Uridine

1982
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Uridine kinase: properties, biological significance and chemotherapeutic aspects (a review).
    Neoplasma, 1976, Volume: 23, Issue:3

    Topics: Animals; Azacitidine; Azauridine; Molecular Weight; Neoplasms, Experimental; Phosphotransferases; Pyrimidine Nucleosides; Pyrimidines; Species Specificity; Uridine; Uridine Kinase; Virus Diseases

1976
Pyrimidine biosynthesis and its regulation in the estrogen-stimulated chick oviduct.
    Archives of biochemistry and biophysics, 1975, Volume: 168, Issue:2

    Topics: Animals; Aspartate Carbamoyltransferase; Azauridine; Bicarbonates; Carbon Radioisotopes; Chickens; Diethylstilbestrol; DNA; Female; Guanosine; Kinetics; Orotic Acid; Oviducts; Phosphotransferases; Pyrimidines; RNA; Uridine

1975
Uridine triphosphate deficiency, growth inhibition, and death in ascites hepatoma cells induced by a combination of pyrimidine biosynthesis inhibition with uridylate trapping.
    Cancer research, 1977, Volume: 37, Issue:3

    Topics: Animals; Azauridine; Carcinoma, Hepatocellular; Cell Division; Cells, Cultured; Female; Galactosamine; Liver Neoplasms; Neoplasm Transplantation; Neoplasms, Experimental; Pyrimidine Nucleotides; Rats; Time Factors; Transplantation, Homologous; Uracil Nucleotides; Uridine; Uridine Diphosphate Galactose; Uridine Diphosphate Glucose; Uridine Monophosphate

1977
Effects of natural pyrimidines and of certain related compounds on the spontaneous activity of the mouse.
    The Journal of pharmacology and experimental therapeutics, 1978, Volume: 207, Issue:2

    Topics: Animals; Azauridine; Barbital; Cytidine; Depression, Chemical; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Mice; Motor Activity; Phenobarbital; Pyrimidines; Thymidine; Thymine; Uracil; Uridine

1978
Increased formation of nucleotide derivatives of 5-fluorouridine in hepatoma cells treated with inhibitors of pyrimidine synthesis and D-galactosamine.
    FEBS letters, 1978, Nov-15, Volume: 95, Issue:2

    Topics: Animals; Azauridine; Biological Transport; Female; Galactosamine; Kinetics; Liver Neoplasms, Experimental; Rats; Ribonucleotides; Uridine

1978
Effects of 6-azauridine on nucleotides, orotic acid, and orotidine in L5178Y mouse lymphoma cells in vitro.
    Cancer research, 1977, Volume: 37, Issue:12

    Topics: Azauridine; Cells, Cultured; Lymphoma; Neoplasms, Experimental; Nucleotides; Orotate Phosphoribosyltransferase; Orotic Acid; Orotidine-5'-Phosphate Decarboxylase; Purine Nucleotides; Pyrimidine Nucleotides; Uridine

1977
Acetylation and cleavage of purine nucleosides. Synthesis of 6-azauridine, 5-fluorouridine, and 5-methyluridine.
    Nucleic acids research, 1976, Volume: 3, Issue:5

    Topics: Azauridine; Magnetic Resonance Spectroscopy; Methods; Optical Rotation; Uridine

1976
Inhibition of turnip yellow mosaic virus synthesis by pyrimidine analogues.
    Biochimica et biophysica acta, 1976, Aug-24, Volume: 444, Issue:1

    Topics: Azauridine; Mosaic Viruses; Phosphates; Plant Viruses; RNA; Thiouracil; Thiouridine; Uracil; Uracil Nucleotides; Uridine; Viral Proteins; Virus Replication

1976
Paramyxovirus-avian cell relationship: discrepant impact of 6-azauridine on virus production by susceptible and less susceptible cells.
    Infection and immunity, 1975, Volume: 11, Issue:5

    Topics: Animals; Azauridine; Carbon Radioisotopes; Chick Embryo; Culture Techniques; Liver; Mumps virus; Myocardium; Paramyxoviridae; RNA, Viral; Tritium; Trypsin; Uridine; Viral Proteins; Virus Cultivation; Virus Replication

1975
Concurrent development of resistance to 6-azauridine and adenosine in a mouse cell line.
    Journal of cellular physiology, 1975, Volume: 86, Issue:2 Pt 1

    Topics: Adenosine; Azauridine; Blood; Cell Division; Cell Line; Cell Survival; Clone Cells; Culture Media; Drug Resistance; Karyotyping; Lethal Dose 50; Phenotype; Uridine

1975
Importance of pyrimidine nucleotide salvage pathways for DNA synthesis in skin.
    The Journal of investigative dermatology, 1976, Volume: 66, Issue:5

    Topics: Animals; Animals, Newborn; Azauridine; Cytidine; DNA; Hydroxyurea; Liver; Methotrexate; Mice; Orotic Acid; Pyrimidine Nucleotides; Rabbits; RNA; Skin; Thymidine; Time Factors; Uridine

1976
Effects of D-glucosamine and 6-azauridine on nucleotide contents, 5-fluorouridine uptake, and cytotoxicity in TA3 mammary tumor cells.
    Journal of the National Cancer Institute, 1986, Volume: 76, Issue:3

    Topics: Adenosine Triphosphate; Animals; Antineoplastic Combined Chemotherapy Protocols; Azauridine; Cytidine Triphosphate; Female; Glucosamine; Guanosine Triphosphate; Mammary Neoplasms, Experimental; Mice; Nucleotides; RNA, Neoplasm; Uridine; Uridine Triphosphate

1986
First clinical experiences with a selective chemotherapy of hepatocellular carcinoma with 5-fluorouridine in combination with other antipyrimidines.
    Advances in enzyme regulation, 1985, Volume: 24

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Azauridine; Carcinoma, Hepatocellular; Female; Galactosamine; Humans; Liver Neoplasms; Male; Middle Aged; Uridine

1985
Enhancement of rat liver uridine kinase activity by various metabolic inhibitors.
    Biochemical pharmacology, 1974, Mar-15, Volume: 23, Issue:6

    Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Azacitidine; Azauridine; Carbon Radioisotopes; Cell-Free System; Cycloheximide; Dactinomycin; Daunorubicin; Diet; Doxorubicin; In Vitro Techniques; Liver; Male; Orotic Acid; Phosphotransferases; Puromycin; Pyrimidines; Rats; Stimulation, Chemical; Thioacetamide; Thymus Gland; Uridine

1974
Uridine kinase level in cells infected with western equine encephalomyelitis, vesicular stomatitis, pseudorabies and polyoma viruses.
    Acta virologica, 1973, Volume: 17, Issue:2

    Topics: Animals; Azauridine; Carbon Isotopes; Cell-Free System; Cells, Cultured; Chick Embryo; Chromatography, Paper; Drug Resistance, Microbial; Encephalitis Virus, Western Equine; Enzyme Induction; Herpesviridae; Mice; Phosphotransferases; Polyomavirus; Pseudorabies; Uridine; Vesicular stomatitis Indiana virus; Virus Replication

1973
Ultrastructural study of liver cell injury due to UTP deficiency.
    Virchows Archiv. B, Cell pathology, 1974, Mar-19, Volume: 15, Issue:2

    Topics: Animals; Azauridine; Cell Nucleolus; Chemical and Drug Induced Liver Injury; Cytoplasm; Endoplasmic Reticulum; Female; Galactosamine; Galactose; Golgi Apparatus; Injections, Intraperitoneal; Liver; Liver Diseases; Microscopy, Electron; Mitochondria; Rats; Ribosomes; Time Factors; Uracil Nucleotides; Uridine

1974
[Effect of 6-azauridine on the reproduction of adenoviruses and effectiveness of its use for adenovirus infections in children].
    Pediatriia, 1972, Volume: 51, Issue:2

    Topics: Adenoviridae; Adenoviridae Infections; Antimetabolites; Azauridine; Child, Preschool; Humans; Infant; Infant, Newborn; Respiratory Tract Infections; Uridine; Virus Replication

1972
The effect of 6-azauridine upon subacute sclerosing panencephalitis virus in tissue cultures.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1972, Volume: 140, Issue:3

    Topics: Animals; Antimetabolites; Antiviral Agents; Azauridine; Culture Techniques; Depression, Chemical; Encephalitis Viruses; Haplorhini; Kidney; Measles virus; Subacute Sclerosing Panencephalitis; Uridine; Virus Replication

1972
Biosynthesis of pyrimidine nucleotides in mouse salivary glands stimulated with isoproterenol.
    The Journal of biological chemistry, 1973, Feb-25, Volume: 248, Issue:4

    Topics: Animals; Aspartate Carbamoyltransferase; Azauridine; Carbamates; Carbon Dioxide; Carbon Isotopes; DNA; Female; Glutamine; Hydrogen-Ion Concentration; Isoproterenol; Mice; Mitosis; Orotic Acid; Phosphotransferases; Pyrimidine Nucleotides; RNA; Solubility; Submandibular Gland; Thymidine; Time Factors; Tritium; Uridine

1973
6-Azauridine, a nucleoside with unusual ribose conformation. The molecular and crystal structure.
    Journal of molecular biology, 1973, Mar-25, Volume: 75, Issue:1

    Topics: Azauridine; Binding Sites; Crystallography; Nucleic Acid Conformation; Uridine

1973
Control of pyrimidine biosynthesis in human lymphocytes. Inhibition of pyrimidine biosynthesis de novo in phytohemagglutinin-stimulated lymphocytes by external uridine and its inhibition mechanism.
    The Journal of biological chemistry, 1973, Jul-10, Volume: 248, Issue:13

    Topics: Aspartate Carbamoyltransferase; Aspartic Acid; Azauridine; Bicarbonates; Carbamates; Carbon Dioxide; Carbon Isotopes; Humans; Lectins; Lymphocytes; Nucleic Acids; Phosphoric Acids; Phosphotransferases; Pyrimidines; Tritium; Uracil Nucleotides; Uridine

1973
[Changes in vascularization of the ventricular myocardium in chick embryo after the administration of different doses of 6-azauridine].
    Ceskoslovenska fysiologie, 1972, Volume: 21, Issue:1

    Topics: Animals; Antimetabolites; Azauridine; Chick Embryo; Coronary Vessels; Fetal Heart; Heart Ventricles; Uridine

1972
Time-response curves in the evaluation of the clinical efficacy of drugs.
    European journal of clinical pharmacology, 1971, Volume: 3, Issue:4

    Topics: Acetates; Administration, Oral; Antimetabolites; Azauridine; Evaluation Studies as Topic; Humans; Models, Biological; Psoriasis; Time Factors; Uridine

1971
[Method for evaluation of the effect of teratogenic agents (6-azauridine) on late development stages].
    Ceskoslovenska fysiologie, 1971, Volume: 20, Issue:6

    Topics: Abnormalities, Drug-Induced; Animals; Antimetabolites; Azauridine; Chick Embryo; Embryonic and Fetal Development; Female; Fetus; Gestational Age; Maternal-Fetal Exchange; Pregnancy; Time Factors; Uridine

1971
Selective enhancement of 5-fluorouridine uptake and action in rat hepatomas in vivo following pretreatment with D-galactosamine and 6-azauridine or N-(phosphonacetyl)-L-aspartate.
    European journal of cancer, 1980, Volume: 16, Issue:9

    Topics: Animals; Aspartic Acid; Azauridine; DNA, Neoplasm; Drug Therapy, Combination; Female; Galactosamine; Liver; Liver Neoplasms, Experimental; Organophosphorus Compounds; Phosphonoacetic Acid; Rats; RNA, Neoplasm; Stimulation, Chemical; Uracil Nucleotides; Uridine

1980
Inhibition of tyrosine aminotransferase induction by UTP deficiency and its reversal by 5-fluorouridine in cultured hepatoma cells.
    Biochimica et biophysica acta, 1981, Aug-27, Volume: 655, Issue:1

    Topics: Animals; Azauridine; Cells, Cultured; Dexamethasone; Enzyme Induction; Galactosamine; Liver Neoplasms, Experimental; Tyrosine Transaminase; Uracil Nucleotides; Uridine; Uridine Triphosphate

1981
Effect of inhibitors of the de novo pyrimidine biosynthetic pathway on serum uridine levels in mice.
    Cancer research, 1981, Volume: 41, Issue:12 Pt 1

    Topics: Amides; Animals; Antimetabolites, Antineoplastic; Aspartic Acid; Azauridine; Galactosamine; Liver; Male; Mice; Organophosphorus Compounds; Phosphonoacetic Acid; Pyrazoles; Pyrimidines; Ribonucleosides; Ribose; Uridine

1981
Transport of uridine and 6-azauridine in human lymphoblastoid cells. Specificity for the uncharged 6-azauridine molecule.
    Molecular pharmacology, 1983, Volume: 23, Issue:1

    Topics: Azauridine; Binding, Competitive; Biological Transport, Active; Cell Line; Cell Membrane; Humans; Hydrogen-Ion Concentration; Kinetics; Lymphocytes; Substrate Specificity; Uridine; Uridine Kinase

1983
Quantitative determination of nucleosides and their phosphate esters--1. The acidic nucleosides, 3-deazauridine and 6-azauridine.
    The International journal of biochemistry, 1984, Volume: 16, Issue:6

    Topics: 3-Deazauridine; Azauridine; Cell Line; Chromatography, DEAE-Cellulose; Humans; Phosphorylation; Spectrophotometry, Ultraviolet; Tritium; Uridine

1984
Potential carcinogenicity of the synthetic 1,3,6-triazine (6-aza) nucleic acid analogues determined by DC polarography. I. Nucleobases.
    Neoplasma, 1996, Volume: 43, Issue:6

    Topics: Aza Compounds; Azauridine; Carcinogenicity Tests; Oxidation-Reduction; Thymine; Uridine

1996
INHIBITION OF RIBONUCLEIC ACID SYNTHESIS IN NEWCASTLE DISEASE VIRUS-INFECTED CELLS BY PUROMYCIN AND 6-AZAURIDINE.
    Journal of bacteriology, 1964, Volume: 88

    Topics: Animals; Azauridine; Carbon Isotopes; Metabolism; Newcastle disease virus; Nucleosides; Pharmacology; Protein Biosynthesis; Proteins; Puromycin; Research; RNA; RNA, Viral; Tissue Culture Techniques; Uridine

1964
Cytidine and deoxycytidylate deaminase inhibition by uridine analogs.
    Biochemical pharmacology, 1980, Mar-01, Volume: 29, Issue:5

    Topics: 3-Deazauridine; Azauridine; Bromodeoxyuridine; Cytidine Deaminase; DCMP Deaminase; Floxuridine; Humans; Kinetics; Uridine

1980