azatoxin has been researched along with etoposide in 2 studies
| Studies (azatoxin) | Trials (azatoxin) | Recent Studies (post-2010) (azatoxin) | Studies (etoposide) | Trials (etoposide) | Recent Studies (post-2010) (etoposide) |
|---|---|---|---|---|---|
| 11 | 0 | 2 | 18,306 | 3,693 | 4,900 |
| Protein | Taxonomy | azatoxin (IC50) | etoposide (IC50) |
|---|---|---|---|
| nuclear receptor coactivator 1 isoform 1 [Homo sapiens] | Homo sapiens (human) | 1.153 | |
| nuclear receptor coactivator 3 isoform a | Homo sapiens (human) | 1.4284 | |
| Polyunsaturated fatty acid lipoxygenase ALOX15 | Oryctolagus cuniculus (rabbit) | 3.187 | |
| Caspase-3 | Homo sapiens (human) | 1 | |
| DNA topoisomerase 2-beta | Homo sapiens (human) | 0.4299 | |
| Solute carrier organic anion transporter family member 1B3 | Homo sapiens (human) | 4.18 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hamel, E; Leteurtre, F; Paull, KD; Pommier, Y; Scudiero, D; Solary, E | 1 |
| Cline, SD; Macdonald, TL; Osheroff, N | 1 |
2 other study(ies) available for azatoxin and etoposide
| Article | Year |
|---|---|
Dual inhibition of topoisomerase II and tubulin polymerization by azatoxin, a novel cytotoxic agent.
Topics: Cell Death; Cell Division; Cell Line; DNA Damage; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Etoposide; Humans; Indoles; Mitosis; Topoisomerase II Inhibitors; Tubulin; Tubulin Modulators; Tumor Cells, Cultured | 1993 |
Azatoxin is a mechanistic hybrid of the topoisomerase II-targeted anticancer drugs etoposide and ellipticine.
Topics: Amino Acid Substitution; Animals; Antineoplastic Agents; Cattle; DNA; Drosophila; Drug Design; Ellipticines; Enzyme Inhibitors; Etoposide; Humans; Indoles; Intercalating Agents; Kinetics; Molecular Structure; Recombinant Proteins; Saccharomyces cerevisiae; Thymus Gland; Topoisomerase II Inhibitors | 1997 |