azathioprine and trimethoprim

azathioprine has been researched along with trimethoprim in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-199012 (46.15)18.7374
1990's0 (0.00)18.2507
2000's5 (19.23)29.6817
2010's9 (34.62)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Knuckley, B; Luo, Y; Thompson, PR1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Ekins, S; Williams, AJ; Xu, JJ1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Saunders, JE; Wickramasinghe, SN1
Hellyar, A; Leaker, B; Mansell, M; Neild, GH; Rudge, C; Thompson, FD1
Berg, KJ; Djøseland, O; Fauchald, P; Gjellestad, A; Mehl, A; Narverud, J; Nordby, G; Rootwelt, K; Talseth, T1
Fukuda, K; Matsuyama, H; Ohyama, M; Shimada, K; Uchizono, A; Yuasa, K1
Fauci, AS; Leavitt, RY1
First, LR; Lipton, J; Nathan, DG; Parkman, R; Rappeport, JM; Smith, BR1
Schmidt-Bäumler, U; Skevas, A1
Hall, CL1
Streem, SB1
Bailey, RR1
Faoagali, JL; McDonald, KS; Moller, PW; Tait, GB1
Bradley, PP; Maxwell, JG; Rothstein, G; Warden, GD1

Reviews

2 review(s) available for azathioprine and trimethoprim

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Pulmonary vasculitis.
    The American review of respiratory disease, 1986, Volume: 134, Issue:1

    Topics: Adrenal Cortex Hormones; Azathioprine; Behcet Syndrome; Chlorambucil; Connective Tissue Diseases; Cyclophosphamide; Cyclosporins; Drug Combinations; Granuloma; Granulomatosis with Polyangiitis; Hemorrhage; Humans; Lung Diseases; Lymphomatoid Granulomatosis; Respiratory Tract Infections; Sulfamethoxazole; Syndrome; Takayasu Arteritis; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination; Vasculitis; Vasculitis, Leukocytoclastic, Cutaneous

1986

Trials

1 trial(s) available for azathioprine and trimethoprim

ArticleYear
Co-trimoxazole and azathioprine: a safe combination.
    British medical journal, 1974, Oct-05, Volume: 4, Issue:5935

    Topics: Administration, Oral; Azathioprine; Cadaver; Clinical Trials as Topic; Drug Therapy, Combination; Humans; Kidney; Kidney Transplantation; Leukopenia; Sulfamethoxazole; Transplantation, Homologous; Trimethoprim; Urinary Tract Infections

1974

Other Studies

23 other study(ies) available for azathioprine and trimethoprim

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Profiling Protein Arginine Deiminase 4 (PAD4): a novel screen to identify PAD4 inhibitors.
    Bioorganic & medicinal chemistry, 2008, Jan-15, Volume: 16, Issue:2

    Topics: Arthritis, Rheumatoid; Chlortetracycline; Combinatorial Chemistry Techniques; Enzyme Inhibitors; Fluorescent Dyes; Hydrolases; Minocycline; Models, Biological; Molecular Structure; Protein-Arginine Deiminase Type 4; Protein-Arginine Deiminases; Streptomycin; Tetracycline

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
    Nature chemical biology, 2009, Volume: 5, Issue:10

    Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Results of three years' experience with the deoxyuridine suppression test.
    Acta haematologica, 1977, Volume: 58, Issue:4

    Topics: Alcoholism; Anemia, Hemolytic; Anemia, Hypochromic; Anticonvulsants; Azathioprine; Deoxyuridine; Epilepsy; Erythrocytes; Erythrocytes, Abnormal; Erythropoiesis; Evaluation Studies as Topic; Folic Acid; Folic Acid Antagonists; Folic Acid Deficiency; Humans; Mercaptopurine; Sulfamethoxazole; Thioguanine; Trimethoprim; Vitamin B 12 Deficiency

1977
Nocardia infection in a renal transplant unit.
    Transplantation proceedings, 1989, Volume: 21, Issue:1 Pt 2

    Topics: Adult; Anti-Infective Agents; Azathioprine; Cross Infection; Cyclosporins; Drug Combinations; Drug Therapy, Combination; Female; Graft Rejection; Hospital Units; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Middle Aged; Nocardia Infections; Prednisolone; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination

1989
Renal effects of trimethoprim in ciclosporin- and azathioprine-treated kidney-allografted patients.
    Nephron, 1989, Volume: 53, Issue:3

    Topics: Adult; Aged; Azathioprine; beta 2-Microglobulin; Creatinine; Cyclosporins; Drug Interactions; Glomerular Filtration Rate; Humans; Kidney Diseases; Kidney Transplantation; Kidney Tubules; Male; Middle Aged; Prospective Studies; Renal Circulation; Trimethoprim; Urea; Uric Acid

1989
Three cases of Wegener's granulomatosis treated with an antimicrobial agent.
    Archives of otolaryngology--head & neck surgery, 1989, Volume: 115, Issue:4

    Topics: Adult; Anti-Infective Agents; Azathioprine; Drug Combinations; Drug Therapy, Combination; Female; Granulomatosis with Polyangiitis; Humans; Male; Middle Aged; Prednisolone; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination

1989
Isolated thrombocytopenia after allogeneic bone marrow transplantation: existence of transient and chronic thrombocytopenic syndromes.
    Blood, 1985, Volume: 65, Issue:2

    Topics: Actuarial Analysis; Adolescent; Adult; Azathioprine; Bone Marrow; Bone Marrow Transplantation; Child; Child, Preschool; Chronic Disease; Graft vs Host Disease; Humans; Prednisone; Sulfamethoxazole; Syndrome; Thrombocytopenia; Time Factors; Transplantation, Homologous; Trimethoprim

1985
[Treatment of Wegener's granuloma with immunosuppressive and steroid drugs (author's transl)].
    Laryngologie, Rhinologie, Otologie, 1974, Volume: 53, Issue:9

    Topics: Adrenal Cortex Hormones; Adult; Azathioprine; Cephalothin; Granulomatosis with Polyangiitis; Humans; Immunosuppressive Agents; Male; Methylprednisolone; Remission, Spontaneous; Streptomycin; Sulfamethoxazole; Tetracycline; Trimethoprim

1974
Genitourinary malacoplakia in renal transplant recipients: pathogenic, prognostic and therapeutic considerations.
    The Journal of urology, 1984, Volume: 132, Issue:1

    Topics: Adult; Anti-Infective Agents, Urinary; Azathioprine; Biopsy; Drug Combinations; Female; Humans; Immunosuppression Therapy; Kidney Transplantation; Malacoplakia; Prognosis; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination; Urinary Bladder; Urinary Bladder Diseases

1984
Leukopenia due to a trimethoprim-azathioprine interaction.
    The New Zealand medical journal, 1984, Oct-24, Volume: 97, Issue:766

    Topics: Azathioprine; Drug Interactions; Humans; Leukopenia; Male; Middle Aged; Trimethoprim

1984
Legionnaires' disease in a patient with polymyositis.
    The New Zealand medical journal, 1980, Jun-25, Volume: 91, Issue:662

    Topics: Adult; Antibodies, Bacterial; Azathioprine; Drug Combinations; Female; Humans; Legionnaires' Disease; Myositis; Pneumonia; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination

1980
Neutropenia and thrombocytopenia in renal allograft recipients treated with trimethoprim-sulfamethoxazole.
    Annals of internal medicine, 1980, Volume: 93, Issue:4

    Topics: Adult; Agranulocytosis; Azathioprine; Bone Marrow; Drug Combinations; Drug Synergism; Humans; Kidney Transplantation; Neutropenia; Retrospective Studies; Sulfamethoxazole; Thrombocytopenia; Transplantation, Homologous; Trimethoprim

1980