azathioprine has been researched along with thioinosine in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (12.50) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (12.50) | 29.6817 |
| 2010's | 12 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Bugge, C; Krasny, HC; Nelson, DJ | 1 |
| Dillmann, I; Fuchs, G; Hinz, N; Lessmöllmann, U; Neubert, D | 1 |
| Albertioni, F; Almer, S; Peterson, C; Pettersson, B; Söderhäll, S | 1 |
| Almer, SH; Bergquist, A; Björnsson, E; Hindorf, U; Jahed, K; Olsson, R; Peterson, C; Prytz, H; Verbaan, H; Wallerstedt, S; Werner, M | 1 |
| Bakker, JA; Bierau, J; Bos, LP; Bus, P; Engels, LG; Gilissen, LP; Hooymans, PM; Masclee, AA; Neef, C; Paulussen, AD; Romberg-Camps, MJ; Stockbrügger, RW; Stronkhorst, A; Wong, DR | 1 |
| Bouma, G; de Boer, NK; Losekoot, N; Mulder, CJ; Peters, GJ; Seinen, ML; Smid, K; van Asseldonk, DP; van Bodegraven, AA | 1 |
| Angelberger, S; Bar-Meir, S; Dilger, K; Greinwald, R; Herrlinger, KR; Lukas, M; Mueller, R; Petritsch, W; Reinisch, W; Schaeffeler, E; Schwab, M; Shonova, O; Stange, EF; Teml, A | 1 |
| Bakker, JA; Bus, P; Engels, LG; Gilissen, LP; Hooymans, PM; Masclee, AA; Neef, C; Pierik, M; Seinen, ML; van Bodegraven, AA; Wong, DR | 1 |
| Beaune, P; Chatellier, G; Chouchana, L; Golmard, JL; Loriot, MA; Narjoz, C; Pineau, B; Roche, D | 1 |
| Almer, S; Andersson, D; Hindorf, U; Peterson, C; Vikingsson, S | 1 |
| Bouma, G; de Boer, NK; Kreijne, JE; Mulder, CJ; Seinen, ML; van Bodegraven, AA; Wilhelm, AJ | 1 |
| Loftus, EV; Moon, W | 1 |
| Coenen, MJ; de Jong, DJ; Derijks, LJ; Engels, LG; Franke, B; Guchelaar, HJ; Hooymans, PM; Klungel, OH; Scheffer, H; van Marrewijk, CJ; Verbeek, AL; Vermeulen, SH; Wong, DR | 1 |
| Boulieu, R; Citterio-Quentin, A; Gustin, MP; Moulsma, M | 1 |
| Bouvy, ML; Broekman, MMTJ; Coenen, MJH; de Jong, DJ; Derijks, LJJ; Guchelaar, HJ; Hooymans, PM; Kievit, W; Klungel, OH; Scheffer, H; van Marrewijk, CJ; Verbeek, ALM; Wanten, GJ; Wong, DR | 1 |
1 review(s) available for azathioprine and thioinosine
| Article | Year |
|---|---|
Review article: recent advances in pharmacogenetics and pharmacokinetics for safe and effective thiopurine therapy in inflammatory bowel disease.
Topics: Azathioprine; Humans; Inflammatory Bowel Diseases; Mercaptopurine; Methyltransferases; Pharmacogenetics; Thioinosine; Thionucleotides | 2016 |
4 trial(s) available for azathioprine and thioinosine
| Article | Year |
|---|---|
Differences between children and adults in thiopurine methyltransferase activity and metabolite formation during thiopurine therapy: possible role of concomitant methotrexate.
Topics: Adult; Age Factors; Antimetabolites, Antineoplastic; Azathioprine; Child; Drug Therapy, Combination; Erythrocytes; Female; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Male; Mercaptopurine; Methotrexate; Methyltransferases; Polymorphism, Genetic; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Thioinosine; Thionucleotides | 2002 |
Therapeutic drug monitoring of thiopurine metabolites in adult thiopurine tolerant IBD patients on maintenance therapy.
Topics: Adolescent; Adult; Aged; Azathioprine; Biomarkers, Pharmacological; Chromatography, High Pressure Liquid; Cross-Sectional Studies; Disease Progression; Dose-Response Relationship, Drug; Drug Monitoring; Female; Genetic Markers; Guanine Nucleotides; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Maintenance Chemotherapy; Male; Medication Adherence; Mercaptopurine; Methyltransferases; Middle Aged; Prospective Studies; Severity of Illness Index; Thioinosine; Thionucleotides; Young Adult | 2012 |
Early prediction of thiopurine-induced hepatotoxicity in inflammatory bowel disease.
Topics: Adult; Aged; Aged, 80 and over; Azathioprine; Chemical and Drug Induced Liver Injury; Cohort Studies; Early Diagnosis; Female; Genotype; Humans; Inflammatory Bowel Diseases; Male; Mercaptopurine; Methyltransferases; Middle Aged; Prognosis; Risk Factors; Thioinosine; Thionucleotides; Treatment Outcome; Young Adult | 2017 |
Patients' beliefs about medicine are associated with early thiopurine discontinuation in patients with inflammatory bowel diseases.
Topics: Adult; Female; Guanine Nucleotides; Health Knowledge, Attitudes, Practice; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Male; Medication Adherence; Mercaptopurine; Middle Aged; Surveys and Questionnaires; Thioinosine; Thionucleotides; Treatment Outcome; Young Adult | 2018 |
11 other study(ies) available for azathioprine and thioinosine
| Article | Year |
|---|---|
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Oxypurine and 6-thiopurine nucleoside triphosphate formation in human erythrocytes.
Topics: Allopurinol; Azathioprine; Erythrocytes; Humans; Inosine Nucleotides; Mercaptopurine; Methionine; Methylation; Purine Nucleotides; Sulfhydryl Compounds; Thioinosine; Thionucleotides; Xanthines | 1977 |
Interference of 6-mercaptopurine riboside, 6-methylmercaptopurine riboside and azathioprine with the morphogenetic differentiation of mouse extremities in vivo and in organ culture.
Topics: Abnormalities, Drug-Induced; Animals; Azathioprine; Depression, Chemical; Drug Interactions; Extremities; Female; Gestational Age; Inosine; Mice; Mice, Inbred C57BL; Organ Culture Techniques; Pregnancy; Thioinosine; Time Factors | 1977 |
Characterisation and utility of thiopurine methyltransferase and thiopurine metabolite measurements in autoimmune hepatitis.
Topics: Adrenal Cortex Hormones; Adult; Aged; Azathioprine; Biomarkers; Cross-Sectional Studies; Female; Follow-Up Studies; Hepatitis, Autoimmune; Humans; Male; Methyltransferases; Middle Aged; Prognosis; Thioguanine; Thioinosine; Thionucleotides; Treatment Outcome | 2010 |
The effect of allopurinol and low-dose thiopurine combination therapy on the activity of three pivotal thiopurine metabolizing enzymes: results from a prospective pharmacological study.
Topics: Adult; Allopurinol; Azathioprine; Drug Therapy, Combination; Enzyme Activation; Enzyme Inhibitors; Fatigue; Female; Guanine Nucleotides; Humans; Hypoxanthine Phosphoribosyltransferase; Immunosuppressive Agents; Inflammatory Bowel Diseases; Male; Mercaptopurine; Methyltransferases; Middle Aged; Nausea; Prospective Studies; Thioinosine; Thionucleotides; Xanthine Oxidase | 2013 |
Mucosal improvement in patients with moderate to severe postoperative endoscopic recurrence of Crohn's disease and azathioprine metabolite levels.
Topics: Adolescent; Adult; Aged; Azathioprine; Biomarkers; Crohn Disease; Drug Administration Schedule; Drug Monitoring; Endoscopy, Gastrointestinal; Female; Guanine Nucleotides; Humans; Immunosuppressive Agents; Intestinal Mucosa; Male; Middle Aged; Recurrence; ROC Curve; Severity of Illness Index; Thioguanine; Thioinosine; Thionucleotides; Treatment Outcome; Young Adult | 2013 |
The pharmacokinetic effect of adalimumab on thiopurine metabolism in Crohn's disease patients.
Topics: Adalimumab; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal, Humanized; Azathioprine; C-Reactive Protein; Crohn Disease; Drug Interactions; Drug Therapy, Combination; Erythrocytes; Female; Guanine Nucleotides; Humans; Hypoxanthine Phosphoribosyltransferase; Immunosuppressive Agents; Inosine Triphosphatase; Male; Methyltransferases; Middle Aged; Prospective Studies; Pyrophosphatases; Severity of Illness Index; Thioinosine; Thionucleotides; Young Adult | 2014 |
Interindividual variability in TPMT enzyme activity: 10 years of experience with thiopurine pharmacogenetics and therapeutic drug monitoring.
Topics: Adult; Azathioprine; Databases, Factual; Drug Monitoring; Female; Genotype; Guanine Nucleotides; Humans; Individuality; Male; Methyltransferases; Middle Aged; Pharmacogenetics; Phenotype; Retrospective Studies; Thioguanine; Thioinosine; Thionucleotides; Young Adult | 2014 |
Novel assay to improve therapeutic drug monitoring of thiopurines in inflammatory bowel disease.
Topics: Adolescent; Adult; Aged; Azathioprine; Cross-Sectional Studies; Drug Monitoring; Erythrocytes; Female; GTP Phosphohydrolases; Guanine Nucleotides; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Male; Mercaptopurine; Methylthioinosine; Middle Aged; Thioguanine; Thioinosine; Thionucleotides; Young Adult | 2014 |
Routinely Established Skewed Thiopurine Metabolism Leads to a Strikingly High Rate of Early Therapeutic Failure in Patients With Inflammatory Bowel Disease.
Topics: Adolescent; Adult; Aged; Azathioprine; Cohort Studies; Colitis, Ulcerative; Crohn Disease; Female; Follow-Up Studies; Guanine Nucleotides; Humans; Immunosuppressive Agents; Male; Mercaptopurine; Middle Aged; Retrospective Studies; Risk Factors; Thioinosine; Thionucleotides; Treatment Failure; Young Adult | 2015 |
ITPA Activity in Adults and Children Treated With or Without Azathioprine: Relationship Between TPMT Activity, Thiopurine Metabolites, and Co-medications.
Topics: Adolescent; Adult; Aged; Azathioprine; Child; Child, Preschool; Female; Guanine Nucleotides; Humans; Immunosuppressive Agents; Infant; Male; Methyltransferases; Middle Aged; Phenotype; Pyrophosphatases; Retrospective Studies; Thioinosine; Thionucleotides; Young Adult | 2017 |