azathioprine and folic acid

azathioprine has been researched along with folic acid in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-199011 (37.93)18.7374
1990's0 (0.00)18.2507
2000's6 (20.69)29.6817
2010's11 (37.93)24.3611
2020's1 (3.45)2.80

Authors

AuthorsStudies
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Saunders, JE; Wickramasinghe, SN1
Wilmanns, W1
Hargrave, MJ; Ibels, LS; McGrath, BP; Raik, E1
Dodsworth, H; Hulme, B; Rault, RM; Wickramasinghe, SN1
Börner, E1
Ghilchik, MW; Morris, AS; Reeves, DS1
Gaeta, JF; Grace, JT; Groenewald, JH; Kenny, GM; Mirand, EA; Murphy, GP; Williams, PD1
Hitchings, GH1
Eastwood, MA; Girdwood, RH; Heading, RC1
Cooper, K; Stafford, J; Turner-Warwick, M1
Carlisle, H; Spector, RG1
Kanno, J; Kure, S; Matsubara, Y; Sato, K; Tominaga, T1
Burakoff, R; Levine, JS1
Mishra, RK; Mishra, S; Nayak, L; Sahu, BK; Senga, Y1
Depla, JA; Van Calster, J1
Caballero, MT; Cevallos, F; Quirce, S; Valdivieso, R1
El-Ashmawy, IM; Gad, SB; Salama, OM1
Budhiraja, P; Popovtzer, M1
Hibi, T; Yajima, T1
Bayad, AE; El-Ashmawy, IM1
AmidŽić Klarić, D; Brusač, E; Jeličić, ML; Keser, S; Mornar, A; Nigović, B1

Reviews

3 review(s) available for azathioprine and folic acid

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Chemotherapy and comparative biochemistry: G. H. A. Clowes memorial lecture.
    Cancer research, 1969, Volume: 29, Issue:11

    Topics: Allopurinol; Animals; Antimetabolites; Azathioprine; Binding Sites; Drug Therapy; Enzyme Inhibitors; Enzyme Precursors; Folic Acid; Folic Acid Antagonists; Humans; Lactobacillus; Leukemia, Myeloid; Liver; Mercaptopurine; Methotrexate; Mice; Molecular Weight; Neoplasms; Nucleic Acids; Proteus; Purines; Research; Species Specificity; Thymine; Transferases; Uric Acid; Xanthine Oxidase

1969
Chemoprophylaxis of colorectal cancer in inflammatory bowel disease: current concepts.
    Inflammatory bowel diseases, 2007, Volume: 13, Issue:10

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Cholagogues and Choleretics; Colorectal Neoplasms; Folic Acid; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Mercaptopurine; Mesalamine; Treatment Outcome; Ursodeoxycholic Acid; Vitamin B Complex

2007

Other Studies

26 other study(ies) available for azathioprine and folic acid

ArticleYear
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Results of three years' experience with the deoxyuridine suppression test.
    Acta haematologica, 1977, Volume: 58, Issue:4

    Topics: Alcoholism; Anemia, Hemolytic; Anemia, Hypochromic; Anticonvulsants; Azathioprine; Deoxyuridine; Epilepsy; Erythrocytes; Erythrocytes, Abnormal; Erythropoiesis; Evaluation Studies as Topic; Folic Acid; Folic Acid Antagonists; Folic Acid Deficiency; Humans; Mercaptopurine; Sulfamethoxazole; Thioguanine; Trimethoprim; Vitamin B 12 Deficiency

1977
[Drug induced megaloblastic anemia].
    Haematology and blood transfusion, 1978, Volume: 21

    Topics: Anemia, Macrocytic; Anemia, Megaloblastic; Antineoplastic Agents; Azathioprine; Bone Marrow; Bone Marrow Cells; DNA; Folic Acid; Folic Acid Antagonists; Humans; Mercaptopurine; Methotrexate; Purines; Pyrimethamine; Tetrahydrofolate Dehydrogenase; Tetrahydrofolates

1978
Erythroid toxicity of azathioprin. Macrocytosis and selective marrow hypoplasis.
    The Quarterly journal of medicine, 1975, Volume: 44, Issue:173

    Topics: Adult; Azathioprine; Blood Cell Count; Bone Marrow; Bone Marrow Diseases; Creatinine; Dose-Response Relationship, Drug; Erythrocyte Count; Erythrocytes; Erythropoiesis; Female; Folic Acid; Hemoglobins; Humans; Kidney Transplantation; Male; Middle Aged; Transplantation, Homologous

1975
Observations on the incidence and cause of macrocytosis in patients on azathioprine therapy following renal transplantation.
    Transplantation, 1974, Volume: 18, Issue:5

    Topics: Anemia, Hypochromic; Azathioprine; Blood Cell Count; Bone Marrow; Bone Marrow Cells; Bone Marrow Examination; Cadaver; Deoxyuridine; DNA; Erythrocytes; Erythrocytes, Abnormal; Female; Folic Acid; Hematocrit; Humans; Kidney Function Tests; Kidney Transplantation; Liver Function Tests; Male; Time Factors; Transplantation, Homologous; Tritium; Vitamin B 12

1974
[Possibilities of the treatment of chronic liver diseases with and without vitamin B 12 -folic acid administration].
    Die Medizinische Welt, 1972, Aug-05, Volume: 23, Issue:31

    Topics: Adult; Aged; Alanine Transaminase; Aspartate Aminotransferases; Azathioprine; Fatty Liver; Female; Folic Acid; Humans; Liver Cirrhosis; Male; Middle Aged; Vitamin B 12

1972
Immunosuppressive powers of the antibacterial agent trimethoprim.
    Nature, 1970, Jul-25, Volume: 227, Issue:5256

    Topics: Animals; Anti-Infective Agents; Azathioprine; Folic Acid; Folic Acid Antagonists; Immunosuppressive Agents; Leucovorin; Mice; Pyrimidines; Skin Transplantation; Transplantation Immunology; Transplantation, Homologous

1970
The effect of PCO (yeast respiratory stimulator) on treated and untreated dog renal allografts.
    Journal of surgical oncology, 1969, Volume: 1, Issue:3

    Topics: Animals; Azathioprine; Biological Products; Bone Marrow; Dogs; Drug Interactions; Female; Folic Acid; Graft Rejection; Immunosuppressive Agents; Kidney; Kidney Function Tests; Kidney Transplantation; Leukocyte Count; Lymphocytes; Male; Time Factors; Transplantation Immunology; Transplantation, Homologous; Yeasts

1969
Macroglobulinaemia treated with prednisone, azathioprine, and folic acid.
    British medical journal, 1970, Sep-26, Volume: 3, Issue:5725

    Topics: Adult; Azathioprine; Blood Cell Count; Bone Marrow Examination; Female; Folic Acid; Humans; Immunoglobulin M; Prednisone; Reticulocytes; Waldenstrom Macroglobulinemia

1970
Wegener's granuloma complicating pregnancy.
    The Journal of obstetrics and gynaecology of the British Commonwealth, 1970, Volume: 77, Issue:11

    Topics: Adult; Azathioprine; Female; Folic Acid; Fumarates; Granulomatosis with Polyangiitis; Humans; Prednisone; Pregnancy; Pregnancy Complications

1970
The effect of anti-metabolites on leptazol induced fits in rats.
    Clinical science, 1971, Volume: 40, Issue:6

    Topics: Animals; Antimetabolites; Azathioprine; Brain; Cytarabine; Daunorubicin; Fluorouracil; Folic Acid; Folic Acid Antagonists; Methotrexate; Pentylenetetrazole; Pyrimethamine; Rats; Seizures

1971
De novo and salvage pathways of DNA synthesis in primary cultured neurall stem cells.
    Brain research, 2006, Feb-03, Volume: 1071, Issue:1

    Topics: Age Factors; Animals; Antimetabolites; Azathioprine; Brain; Cell Count; Cell Proliferation; Cells, Cultured; Colony-Forming Units Assay; Deoxyribonucleosides; DNA; DNA Replication; Dose-Response Relationship, Drug; Embryo, Mammalian; Enzyme Inhibitors; Fluorescent Antibody Technique; Folic Acid; Glial Fibrillary Acidic Protein; In Situ Nick-End Labeling; Intermediate Filament Proteins; Methotrexate; Mice; Mice, Inbred C57BL; Microtubule-Associated Proteins; Models, Biological; Nerve Tissue Proteins; Nestin; Neurons; O Antigens; Stem Cells; Time Factors; Tubulin; Vitamin B Complex

2006
Differential growth of the freshwater mussel, Lamellidens marginalis in relation to certain drugs.
    Environmental toxicology, 2008, Volume: 23, Issue:3

    Topics: Animals; Azathioprine; Betamethasone; Body Size; Calcium; Folic Acid; Stanozolol; Unionidae; Water Pollutants, Chemical

2008
Serpiginous choroiditis treated in a stepladder approach.
    Bulletin de la Societe belge d'ophtalmologie, 2007, Issue:306

    Topics: Azathioprine; Choroiditis; Drug Administration Schedule; Drug Therapy, Combination; Folic Acid; Humans; Male; Methotrexate; Methylprednisolone; Middle Aged; Recurrence

2007
Chronic urticaria caused by folic acid.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2009, Volume: 103, Issue:1

    Topics: Aged; Anemia, Hemolytic, Autoimmune; Azathioprine; Drug Hypersensitivity; Female; Folic Acid; Humans; Leucovorin; Purpura, Thrombocytopenic, Idiopathic; Urticaria

2009
Grape seed extract prevents azathioprine toxicity in rats.
    Phytotherapy research : PTR, 2010, Volume: 24, Issue:11

    Topics: Animals; Antioxidants; Azathioprine; Folic Acid; Glutathione; Grape Seed Extract; Lipid Peroxidation; Liver; Liver Diseases; Male; Malondialdehyde; Oxidative Stress; Phagocytosis; Rats; Rats, Wistar

2010
Azathioprine-related myelosuppression in a patient homozygous for TPMT*3A.
    Nature reviews. Nephrology, 2011, Jun-28, Volume: 7, Issue:8

    Topics: Azathioprine; Erythrocyte Transfusion; Filgrastim; Folic Acid; Genotype; Granulocyte Colony-Stimulating Factor; Homozygote; Humans; Immunosuppressive Agents; Kidney Function Tests; Kidney Transplantation; Liver Function Tests; Male; Methyltransferases; Middle Aged; Pancreas Transplantation; Pancytopenia; Recombinant Proteins

2011
[Chemoprevention of colorectal cancer associated with IBD].
    Nihon rinsho. Japanese journal of clinical medicine, 2012, Volume: 70 Suppl 1

    Topics: Azathioprine; Colorectal Neoplasms; Crohn Disease; Folic Acid; Humans; Inflammatory Bowel Diseases; Mercaptopurine; Mesalamine

2012
Folic Acid and Grape Seed Extract Prevent Azathioprine-induced Fetal Malformations and Renal Toxicity in Rats.
    Phytotherapy research : PTR, 2016, Volume: 30, Issue:12

    Topics: Animals; Antioxidants; Azathioprine; Female; Fetal Diseases; Folic Acid; Grape Seed Extract; Kidney; Male; Pregnancy; Pregnancy Complications; Rats; Rats, Wistar

2016
Development of a HPLC-DAD stability-indicating method and compatibility study of azathioprine and folic acid as a prerequisite for a monolayer fixed-dose combination.
    Analytical methods : advancing methods and applications, 2021, 03-21, Volume: 13, Issue:11

    Topics: Azathioprine; Calorimetry, Differential Scanning; Chromatography, High Pressure Liquid; Folic Acid

2021