Compounds > azathioprine

azathioprine and digoxin

azathioprine has been researched along with digoxin in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19903 (20.00)18.7374
1990's0 (0.00)18.2507
2000's3 (20.00)29.6817
2010's9 (60.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Altman, DG; Royston, JP1
Davies, JA; McNicol, GP1
Breslin, AB; Morgan, JJ; Seldon, WA; Shanahan, MX1
Masuyama, J; Minota, S; Nagashima, T; Okubo, H1

Reviews

2 review(s) available for azathioprine and digoxin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Advances in medicine.
    The Practitioner, 1972, Volume: 209, Issue:252

    Topics: Anemia, Macrocytic; Anti-Arrhythmia Agents; Anticoagulants; Azathioprine; Chemical and Drug Induced Liver Injury; Cholelithiasis; Clofibrate; Colitis, Ulcerative; Dextrans; Digoxin; Drug Therapy; Fibrinolytic Agents; Halothane; Heparin; Hepatitis B Antigens; Humans; Hyperthyroidism; Iodine Isotopes; Leukemia; Myocardial Infarction; Platelet Adhesiveness; Pulmonary Embolism; Thrombosis; Venoms

1972

Trials

1 trial(s) available for azathioprine and digoxin

ArticleYear
The hidden effect of time.
    Statistics in medicine, 1988, Volume: 7, Issue:6

    Topics: Aged; Azathioprine; Bilirubin; Blood Pressure Determination; Circadian Rhythm; Clinical Trials as Topic; Creatinine; Digoxin; Humans; Liver Cirrhosis, Biliary; Metabolic Clearance Rate; Research Design; Seasons; Statistics as Topic; Time; Time Factors

1988

Other Studies

12 other study(ies) available for azathioprine and digoxin

ArticleYear
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
A heart transplantation. 5. Postoperative medical aspects.
    The Medical journal of Australia, 1969, Mar-29, Volume: 1, Issue:13

    Topics: Anti-Bacterial Agents; Antilymphocyte Serum; Arrhythmias, Cardiac; Australia; Azathioprine; Betamethasone; Blood Pressure; Blood Sedimentation; Digoxin; Edema; Electrocardiography; Furosemide; Glycosuria; Heart Auscultation; Heart Transplantation; Hemorrhage; Humans; Hydrocortisone; Hydroxybutyrate Dehydrogenase; Immunosuppressive Agents; Infections; Infusions, Parenteral; Injections, Intramuscular; Injections, Intravenous; Intensive Care Units; Isoproterenol; Male; Middle Aged; Postoperative Complications; Respiration; Transplantation Immunology; Transplantation, Homologous; Veins

1969
Marked dilatation of pulmonary arteries in mixed connective tissue disease.
    The Journal of rheumatology, 2005, Volume: 32, Issue:6

    Topics: Activities of Daily Living; Azathioprine; Blood Pressure; Digoxin; Dilatation, Pathologic; Drug Therapy, Combination; Female; Furosemide; Humans; Hypertension, Pulmonary; Mixed Connective Tissue Disease; Pulmonary Artery; Radiography; Treatment Outcome

2005