Compounds > azathioprine

azathioprine and carbon tetrachloride

azathioprine has been researched along with carbon tetrachloride in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19905 (50.00)18.7374
1990's1 (10.00)18.2507
2000's0 (0.00)29.6817
2010's4 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Ekins, S; Williams, AJ; Xu, JJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bremmelgaard, A; Dupont, B; Jorgensen, M; Keiding, S; Ranek, L; Thomsen, P; Tyrsted, G1
Schmidt, E; Schmidt, FW1
Fujiwara, M; Kobayashi, M; Nagashima, H; Nakatsukasa, H; Sakata, T; Shiota, T; Takei, N; Watanabe, A1
Sakata, T1
Hobara, N; Watanabe, A1
Fouad, FM; Mamer, OA; Shahidi, F1

Reviews

1 review(s) available for azathioprine and carbon tetrachloride

ArticleYear
[Immunopathology of chronic hepatitis and results of therapy with cytostatics].
    Deutsches medizinisches Journal, 1969, Volume: 20, Issue:15

    Topics: Animals; Autoantibodies; Azathioprine; Carbon Tetrachloride; Cell Membrane Permeability; Cell Nucleus; Chronic Disease; Hepatitis; Humans; Immunosuppressive Agents; Liver; Lymphocytes; Mercaptopurine; Microscopy, Electron; Mitochondria, Liver; Rats

1969

Other Studies

9 other study(ies) available for azathioprine and carbon tetrachloride

ArticleYear
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
The effects of azathioprine on CCl4 induced cirrhosis in the rat.
    Beitrage zur Pathologie, 1974, Volume: 152, Issue:1

    Topics: Adenosine Triphosphate; Animals; Azathioprine; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Disease Models, Animal; DNA; Female; Hydroxyproline; Liver; Liver Cirrhosis; Liver Cirrhosis, Experimental; Organ Size; Proteins; Rats; RNA; Triglycerides

1974
Effect of azathioprine and carbon tetrachloride on induction of hyperplastic liver nodule and hepatocellular carcinoma by diethylnitrosamine and N-2-fluorenylacetamide in rats.
    Annals of the New York Academy of Sciences, 1983, Volume: 417

    Topics: 2-Acetylaminofluorene; Aniline Hydroxylase; Animals; Azathioprine; Carbon Tetrachloride; Diethylnitrosamine; Drug Interactions; gamma-Glutamyltransferase; Liver; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Nitrosamines; Rats; Rats, Inbred Strains

1983
Effects of carbon tetrachloride and azathioprine on diethylnitrosamine and N-2-fluorenylacetamide-induced hyperplastic liver nodule and hepatocellular carcinoma.
    Acta medica Okayama, 1984, Volume: 38, Issue:6

    Topics: 2-Acetylaminofluorene; Aniline Hydroxylase; Animals; Azathioprine; Carbon Tetrachloride; Diethylnitrosamine; Drug Interactions; Hyperplasia; Isoenzymes; Leucine Transaminase; Liver; Liver Neoplasms, Experimental; Male; Nitrosamines; Ornithine Decarboxylase; Rats; Rats, Inbred Strains; Transaminases

1984
Impaired metabolism of azathioprine in carbon tetrachloride-injured rats.
    Hepato-gastroenterology, 1981, Volume: 28, Issue:4

    Topics: Animals; Azathioprine; Carbon Tetrachloride; Female; Glutathione; Glutathione Transferase; Liver; Maleates; Metabolic Clearance Rate; Probenecid; Rats; Rats, Inbred Strains

1981
Acute-phase response in rat to carbon tetrachloride-azathioprine induced cirrhosis and partial hepatectomy of cirrhotic liver.
    Journal of toxicology and environmental health, 1996, Apr-19, Volume: 47, Issue:6

    Topics: Acute-Phase Reaction; alpha 1-Antitrypsin; Animals; Antimetabolites; Azathioprine; Carbon Tetrachloride; Complement C3; Corn Oil; Disease Models, Animal; DNA; Female; Haptoglobins; Hepatectomy; Lipoproteins; Liver; Liver Cirrhosis, Experimental; Macroglobulins; Male; Orosomucoid; Rats; Rats, Wistar; RNA, Messenger; Serum Albumin; Specific Pathogen-Free Organisms

1996