azathioprine and allopurinol

azathioprine has been researched along with allopurinol in 137 studies

Research

Studies (137)

Timeframe	Studies, this research(%)	All Research%
pre-1990	35 (25.55)	18.7374
1990's	15 (10.95)	18.2507
2000's	21 (15.33)	29.6817
2010's	55 (40.15)	24.3611
2020's	11 (8.03)	2.80

Authors

Authors	Studies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y	1
Flury, W; Montandon, A; Ruch, HR	1
Hruby, K; Kopsa, H; Pils, P; Schmidt, P; Zazgornik, J	1
Carpenter, CB; Hager, ET; Merrill, JP; Mocelin, AJ	1
Glogner, P; Hopf, U; Stockhausen, G	1
Bugge, C; Krasny, HC; Nelson, DJ	1
Glogner, P; Heni, N	1
Kaiser, E; Müller, MM	1
Boyd, IW	1
Lee, HA; Sharman, VL; Venkat Raman, G	1
Nordstrom, D	1
Erdmann, E; Greif, J	1
Griggs, RC; Kissel, JT; Levy, RJ; Mendell, JR	1
O'Sullivan, WJ	1
Fellner, R; Fellner, S; Klein, G	1
Marshall, VC	1
Bertino, JR; Prager, D; Rosman, M	1
Rothermich, NO	1
Greene, ML; Henderson, JF; Kelley, WN; Rosenbloom, FM; Seegmiller, JE	1
Ginn, HE	1
Wilmanns, W	1
Hitchings, GH	1
Nies, AS; Oates, JA	1
Crummy, CS; Moquin, RB; Perlin, E	1
Datko, LJ; Kassarich, J; Rosenthale, ME; Schneider, F	1
Kurumada, T; Maruyama, H; Mizuno, T; Onisawa, J; Segawa, M	1
Atkinson, MR; Chalmers, AH; Knight, PR	1
Benke, PJ; Sorensen, LB	1
Didlake, R; Files, JC; Kirchner, KA; Krueger, RP; Raju, S	1
Brown, CB; Fox, M; Lennard, L; Maddocks, JL	1
Ahlmén, J; Brynger, J	1
Breuer, RI; Kehoe, TJ; Krowka, MJ	1
Brooks, RJ; Dorr, RT; Durie, BG	1
Epifanova, OI; Loginov, BV; Makarova, GF	1
Hoffman, R; Toledo-Pereyra, LH	1
Hausamen, TU; Reinicke, H; Weber, FW	1
Kokot, F	1
Deutsch, E; Kopsa, H; Kuschan, K; Pils, P; Schmidt, P; Zazgornik, J	1
Bahloul, Z; Ben Hmida, M; Hachicha, J; Jarraya, A; Jarraya, F; Kaddour, N; Kharrat, M	1
Arap, S; Cameron, JS; Chocair, PR; Duley, JA; Ianhez, L; Sabbaga, E; Simmonds, HA	1
Amirou, M; Bayle, F; Bechtel, Y; Bessard, G; Boujet, C; Serre-Debeauvais, F; Vialtel, P	1
Arap, S; Cameron, JS; Chocair, P; Duley, J; Ianhez, L; Sabbaga, E; Simmonds, HA	1
Bernstein, LS	1
Banner, N; Cummins, D; Halil, O; Sekar, M	1
Armstrong, VW; Gummert, J; Mohr, FW; Oellerich, M; Schütz, E	1
Allen, LV; Erickson, MA	1
Hayney, MS; Kennedy, DT; Lake, KD	1
Aziz, T; Campbell, C; Deiraniya, A; el-Gamel, A; Evans, C; Keevil, B; Rahman, A; Yonan, N	1
Alonso-Ruiz, A; Calabozo, M; Duruelo, J; Perez-Ruiz, F	1
Chrzanowska, M; Krzymański, M	1
Bechtel, PR; Bechtel, YC; Brientini, MP; Hrusovsky, S; Lelouët, H; Mantion, G; Miguet, JP; Paintaud, G	1
Jenkins, PG	1
Amenabar, JJ; Calabozo, M; Gomez-Ullate, P; Herrero-Beites, AM; Nolla, JM; Perez-Ruiz, F; Zarraga, S	1
Farrell, GC; Jones, BE; Tapner, MJ; Wu, WM	1
Seidel, W	1
Cao, D; Friedman, S; Hanauer, SB; Hande, SA; Lim, WC; Reddy, SI; Sparrow, MP	1
Duley, JA; Florin, TH	1
Chocair, PR; Duley, JA; Florin, TH	1
Derijks, LJ; Gilissen, LP; Hommes, DW; Hooymans, PM	1
Edwards, NL	1
Egan, LJ	1
Cao, D; Friedman, S; Hanauer, SB; Hande, SA; Sparrow, MP	1
den Dulk, MO; Derijks, LJ; Gemmeke, EH; Hooymans, PM; Wong, DR	1
Ansari, A; Aslam, Z; De Sica, A; Duley, J; Fairbanks, L; Gilshenan, K; Marinaki, A; Sanderson, J; Smith, M	1
Gearry, RB; Leong, RW; Sparrow, MP	1
Feller, ER; Lam, MY; Lonks, JR; Shah, SA	1
Ansari, A; Arenas, M; Duley, J; Lewis, CM; Marinaki, AM; Sanderson, JD; Shobowale-Bakre, M; Smith, MA	1
Ansari, A; Duley, JA; Florin, TH; O'Donohue, J; Patel, N; Sanderson, J	1
Barclay, ML; Day, AS; Gearry, RB; Leong, RW; Sparrow, MP	1
Goetschel, P; Laube, GF; Trück, J; von Vigier, RO	1
Sparrow, MP	1
Barclay, ML; Gearry, RB; Roberts, RL	1
Govani, SM; Higgins, PD	1
Barclay, ML; Burt, MJ; Chalmers-Watson, T; Chapman, BA; Gardiner, SJ; Gearry, RB; Huelsen, A; Ross, AG; Stedman, CA	1
Andersson, P; Hindorf, U	1
Bouma, G; de Boer, NK; Peters, GJ; Seinen, ML; Smid, K; van Asseldonk, DP; van Bodegraven, AA	1
Anderson, SH; Blaker, P; Irving, PM; Marinaki, AM; Sanderson, JD; Smith, MA	1
Bouma, G; de Boer, NK; Hanauer, SB; Harrell, LE; Hoentjen, F; Rubin, DT; Seinen, ML; van Bodegraven, AA	1
Appell, ML; Hindorf, U; Wagner, A	1
Aomori, T; Araki, T; Hiromura, K; Nagamine, A; Nakamura, T; Nojima, Y; Okada, Y; Takenaka, M; Yamamoto, K	1
Al-Shamma, S; Eross, B; Mclaughlin, S	1
Ampuero, J; Castro-Fernández, M; Millán, M; Romero-Gómez, M	1
Bouma, G; de Boer, NK; Losekoot, N; Mulder, CJ; Peters, GJ; Seinen, ML; Smid, K; van Asseldonk, DP; van Bodegraven, AA	1
Bouma, G; de Boer, NK; de Boer, YS; Mulder, CJ; van Gerven, NM; van Nieuwkerk, CM	1
Burke, PA; Gakhal, M; Malebranche, L; Rahman, E; Saltzberg, M	1
Curkovic, I; Frei, P; Fried, M; Jetter, A; Kullak-Ublick, GA; Rentsch, KM; Rogler, G	1
Arenas-Hernandez, M; Blaker, PA; Fairbanks, L; Irving, PM; Marinaki, AM; Sanderson, JD; Shobowale-Bakre, EA; Smith, MA	1
Fukami, T; Higuchi, S; Matsuo, K; Nakajima, M; Sasaki, E; Takai, S; Tsuneyama, K; Yokoi, T	1
Baek, MC; Cho, YE; Moon, PG	1
McCabe, RP; Min, MX; Weinberg, DI	1
Bégin, J; Doré, M; Frenette, AJ; Mansour, AM; Troyanov, Y	1
Beswick, L; Friedman, AB; Sparrow, MP	1
Aellig, N; Corti, N; Fauchère, I; Jetter, A; Weiler, S	1
Al Maruf, A; O'Brien, PJ; Wan, L	1
Kiszka-Kanowitz, M; Nielsen, AM; Theede, K	2
Broekman, MM; de Jong, DJ; Hoentjen, F; Kerstholt, M; Leijten, A; Peters, WH; Roelofs, HM; Wanten, GJ; Wong, DR	1
Ansari, A; Duley, J; Florin, T; Nelson-Piercy, C; Sheikh, M	1
De Iudicibus, S; Decorti, G; Dei Rossi, S; Londero, M; Martelossi, S; Pelin, M; Spizzo, R; Stocco, G; Ventura, A	1
de Boer, NK; Leijte, NN; Meijer, B; Mulder, CJ; Seinen, ML; van Bodegraven, AA	1
Abdulrehman, A; Ansari, A; Bull, C; Duley, J; Kerr, P; Pavlidis, P; Stamoulos, P	1
Kiszka-Kanowitz, M; Mertz-Nielsen, A; Theede, K	1
Ansari, A; Berry, P; Coulthard, SA; McGarrity, S; McLaughlin, S; Redfern, CPF	1
Bouma, G; de Boer, NKH; Meijer, B; Mulder, CJJ; Seinen, ML; van Bodegraven, AA; van Egmond, R	1
Dart, RJ; Irving, PM	1
Bruijnzeel-Koomen, CAF; De Bruin-Weller, MS; de Graaf, M; Garritsen, FM; Hijnen, DJ; van den Broek, MPH; van der Schaft, J	1
Bampton, P; Barclay, ML; Brown, SJ; Chung, A; Friedman, AB; Gibson, PR; Hanauer, SB; Macrae, FA; McKenzie, J; Reynolds, J; Sparrow, MP	1
Beswick, L; Friedman, AB; Haridy, J; Moltzen, A; Raghunath, A; Sparrow, M; van Langenberg, D; Vasudevan, A	1
Boyle, B; Bricker, J; Crandall, W; Dotson, JL; Kim, SC; Maltz, R; Serpico, MR	1
Friedman, AB; Sparrow, MP	1
Ansari, AR; Aziz, A	1
Krijt, J; Pavelcova, K; Petru, L; Stiburkova, B	1
Bolia, R; Hardikar, W; Rajanayagam, J	1
Allin, KH; Burisch, J; Gluud, LL; Hansen, S; Jensen, CB; Jess, T; Kiszka-Kanowitz, M; Nielsen, AM; Theede, K; Thomsen, SB	1
Bouma, G; de Boer, NK; de Jong, DJ; de Veer, RC; de Vries, AC; Dijkstra, G; Kreijne, JE; van der Woude, CJ; van Moorsel, SAW; Voskuil, MD; West, R	1
Czaja, AJ	1
de Boer, A; Egberts, ACG; Houwen, JPA; Houwen, RHJ; Lalmohamed, A; van Maarseveen, EM	1
Hsia, CC; Jones, E; Madrazo, L	1
Bi, HC; Chen, BL; Ding, L; Gao, X; Hu, PJ; Huang, L; Huang, M; Liu, H; Lv, C; Wang, XD; Zhang, FB; Zhang, Y	1
Anderson, SHC; Ansari, AR; Bayoumy, AB; de Boer, NKH; Hayee, B; Mateen, BA; Mulder, CJJ; Nolan, JD; van Liere, ELSA; Warner, B	1
Abad-Santos, F; Campodónico, D; Casajús, A; Gómez, A; Mejía-Abril, G; Méndez, M; Navares-Gómez, M; Novalbos, J; Ochoa, D; Román, M; Soria-Chacartegui, P; Villapalos-García, G; Zubiaur, P	1
Giri, S; Sundaram, S	1
Sparrow, MP; Turbayne, AK	1
Borrelli, O; Buckingham, R; Chadokufa, S; Cococcioni, L; El-Kouly, S; Gaynor, E; Kiparissi, F; Pensabene, L; Puoti, MG; Saliakellis, E	1

Reviews

18 review(s) available for azathioprine and allopurinol

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
An updated look at antirheumatic drugs. The Medical clinics of North America, 1967, Volume: 51, Issue:5 Topics: Allopurinol; Anti-Inflammatory Agents; Arthritis; Azathioprine; Chloroquine; Cyclophosphamide; Glucocorticoids; Humans; Immunosuppressive Agents; Indomethacin; Methotrexate; Nitrogen Mustard Compounds; Rheumatic Diseases; Salicylates	1967
Hypoxanthine-guanine phosphoribosyltransferase deficiency in gout. Annals of internal medicine, 1969, Volume: 70, Issue:1 Topics: Adenine; Adolescent; Adult; Allopurinol; Azathioprine; Child; Child, Preschool; Female; Gout; Humans; Hypoxanthines; Male; Middle Aged; Pedigree; Pharmacogenetics; Phenotype; Purines; Transferases; Uric Acid	1969
Late medical complications of renal transplantation. Archives of internal medicine, 1969, Volume: 123, Issue:5 Topics: Adrenal Cortex Hormones; Adult; Allopurinol; Autoimmune Diseases; Azathioprine; Bone Diseases; Diabetes Mellitus; Drug Synergism; Duodenal Ulcer; Embolism, Fat; Glomerulonephritis; Histocompatibility; Humans; Hypertension, Renal; Immunosuppressive Agents; Infections; Kidney Glomerulus; Kidney Transplantation; Malabsorption Syndromes; Male; Mercaptopurine; Neoplasm Transplantation; Neoplasms; Obesity; Osteoporosis; Pancreatitis; Peptic Ulcer Hemorrhage; Phenylbutazone; Postoperative Complications; Proteinuria; Transplantation, Homologous	1969
[Antimetabolites]. Der Internist, 1971, Volume: 12 Topics: Allopurinol; Animals; Antimetabolites; Azathioprine; Cell Division; Chemical Phenomena; Chemistry; Cytarabine; DNA, Neoplasm; Fluorouracil; Folic Acid Antagonists; Humans; Leukemia; Mercaptopurine; Methotrexate; Neoplasms; Pyrimidines; Thioguanine	1971
Chemotherapy and comparative biochemistry: G. H. A. Clowes memorial lecture. Cancer research, 1969, Volume: 29, Issue:11 Topics: Allopurinol; Animals; Antimetabolites; Azathioprine; Binding Sites; Drug Therapy; Enzyme Inhibitors; Enzyme Precursors; Folic Acid; Folic Acid Antagonists; Humans; Lactobacillus; Leukemia, Myeloid; Liver; Mercaptopurine; Methotrexate; Mice; Molecular Weight; Neoplasms; Nucleic Acids; Proteus; Purines; Research; Species Specificity; Thymine; Transferases; Uric Acid; Xanthine Oxidase	1969
Thiopurine therapies: problems, complexities, and progress with monitoring thioguanine nucleotides. Therapeutic drug monitoring, 2005, Volume: 27, Issue:5 Topics: Azathioprine; Drug Monitoring; Guanosine Diphosphate; Guanosine Triphosphate; Humans; Leukopenia; Mercaptopurine; Methylation; Methyltransferases; Nausea; Thioguanine; Thionucleotides; Xanthine Oxidase	2005
Review article: thiopurines in inflammatory bowel disease. Alimentary pharmacology & therapeutics, 2006, Sep-01, Volume: 24, Issue:5 Topics: Azathioprine; Drug Interactions; Gastrointestinal Agents; Genotype; Humans; Inflammatory Bowel Diseases; Mercaptopurine; Methyltransferases; Phenotype; Purines; Thioguanine; Treatment Outcome; Xanthine Oxidase	2006
Thiopurine hepatotoxicity in inflammatory bowel disease: the role for adding allopurinol. Expert opinion on drug safety, 2008, Volume: 7, Issue:5 Topics: Allopurinol; Azathioprine; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Drug Interactions; Drug Monitoring; Enzyme Inhibitors; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Liver Diseases; Mercaptopurine	2008
Azathioprine and allopurinol: A two-edged interaction. Journal of gastroenterology and hepatology, 2010, Volume: 25, Issue:4 Topics: Allopurinol; Asian People; Azathioprine; Consumer Product Safety; Drug Interactions; Drug Labeling; Drug Monitoring; Drug Therapy, Combination; Humans; Immunosuppressive Agents; Methyltransferases; New South Wales; Polymorphism, Single Nucleotide; Risk Factors	2010
Allopurinol enhanced thiopurine treatment for inflammatory bowel disease: safety considerations and guidelines for use. Journal of clinical pharmacy and therapeutics, 2014, Volume: 39, Issue:2 Topics: Allopurinol; Azathioprine; Drug Monitoring; Drug Therapy, Combination; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Mercaptopurine; Practice Guidelines as Topic	2014
The role of thiopurine metabolite monitoring in inflammatory bowel disease. Expert review of gastroenterology & hepatology, 2014, Volume: 8, Issue:4 Topics: Allopurinol; Antimetabolites; Azathioprine; Drug Monitoring; Humans; Inflammatory Bowel Diseases; Mercaptopurine; Methyltransferases	2014
[Optimized thiopurine treatment in chronic inflammatory bowel disease]. Ugeskrift for laeger, 2014, May-26, Volume: 176, Issue:22 Topics: Algorithms; Allopurinol; Antimetabolites; Azathioprine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Mercaptopurine; Methyltransferases	2014
[Optimized thiopurine treatment in chronic inflammatory bowel disease]. Ugeskrift for laeger, 2015, Jun-22, Volume: 177, Issue:26 Topics: Algorithms; Allopurinol; Antimetabolites; Azathioprine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Mercaptopurine; Methyltransferases	2015
Thiopurine Biotransformation and Pharmacological Effects: Contribution of Oxidative Stress. Current drug metabolism, 2016, Volume: 17, Issue:6 Topics: Animals; Antimetabolites; Azathioprine; Biotransformation; Glutathione; Glutathione Transferase; Humans; Liver; Mercaptopurine; Metabolic Detoxication, Phase II; Oxidative Stress; Pharmacogenetics; Polymorphism, Single Nucleotide; Pyrophosphatases; Reactive Oxygen Species; Risk Factors; Xanthine Oxidase	2016
Optimising use of thiopurines in inflammatory bowel disease. Expert review of clinical immunology, 2017, Volume: 13, Issue:9 Topics: Allopurinol; Drug Dosage Calculations; Drug Therapy, Combination; Humans; Immunologic Factors; Inflammatory Bowel Diseases; Mercaptopurine; Practice Guidelines as Topic	2017
Review article: opportunities to improve and expand thiopurine therapy for autoimmune hepatitis. Alimentary pharmacology & therapeutics, 2020, Volume: 51, Issue:12 Topics: Allopurinol; Azathioprine; Drug-Related Side Effects and Adverse Reactions; Guanine Nucleotides; Hepatitis, Autoimmune; Humans; Inflammatory Bowel Diseases; Mercaptopurine; Purines; Quality Improvement; Thioguanine; Thionucleotides; Treatment Outcome	2020
Low-Dose Azathioprine in Combination with Allopurinol: The Past, Present and Future of This Useful Duo. Digestive diseases and sciences, 2022, Volume: 67, Issue:12 Topics: Allopurinol; Azathioprine; Humans; Immunologic Factors; Immunosuppressive Agents; Inflammatory Bowel Diseases; Mercaptopurine	2022

Trials

9 trial(s) available for azathioprine and allopurinol

Article	Year
[Indomethacin in rheumatic diseases with special reference to ophthalmologic studies]. Medizinische Klinik, 1972, Feb-25, Volume: 67, Issue:8 Topics: Allopurinol; Arthritis, Rheumatoid; Azathioprine; Blood Cells; Capsules; Clinical Trials as Topic; Eye Diseases; Female; Gastrointestinal Diseases; Gout; Humans; Indomethacin; Lupus Erythematosus, Systemic; Male; Middle Aged; Rheumatic Diseases; Scleroderma, Systemic; Spondylitis, Ankylosing; Suppositories	1972
Does low-dose allopurinol, with azathioprine, cyclosporin and prednisolone, improve renal transplant immunosuppression? Advances in experimental medicine and biology, 1994, Volume: 370 Topics: Adult; Allopurinol; Azathioprine; Case-Control Studies; Creatinine; Cyclosporine; Drug Therapy, Combination; Female; Follow-Up Studies; Graft Rejection; Humans; Immunosuppressive Agents; Kidney Transplantation; Leukocyte Count; Male; Prednisolone	1994
Low-dose allopurinol plus azathioprine/cyclosporin/prednisolone, a novel immunosuppressive regimen. Lancet (London, England), 1993, Jul-10, Volume: 342, Issue:8863 Topics: Allopurinol; Azathioprine; Cyclosporine; Drug Therapy, Combination; Female; Graft Rejection; Humans; Immunosuppression Therapy; Kidney Transplantation; Male; Prednisolone	1993
Effect of allopurinol on the metabolism of azathioprine in heart transplant patients. Transplantation proceedings, 1998, Volume: 30, Issue:4 Topics: Allopurinol; Azathioprine; Erythrocytes; Graft Rejection; Guanine Nucleotides; Heart Transplantation; Humans; Immunosuppressive Agents; Regression Analysis; Thionucleotides	1998
Allopurinol enhances the activity of hypoxanthine-guanine phosphoribosyltransferase in inflammatory bowel disease patients during low-dose thiopurine therapy: preliminary data of an ongoing series. Nucleosides, nucleotides & nucleic acids, 2011, Volume: 30, Issue:12 Topics: Adolescent; Adult; Allopurinol; Azathioprine; Child; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Gout Suppressants; Humans; Hypoxanthine Phosphoribosyltransferase; Inflammatory Bowel Diseases; Male; Mercaptopurine; Middle Aged; Young Adult	2011
Safety and effectiveness of long-term allopurinol-thiopurine maintenance treatment in inflammatory bowel disease. Inflammatory bowel diseases, 2013, Volume: 19, Issue:2 Topics: Adolescent; Adult; Allopurinol; Azathioprine; Colitis, Ulcerative; Crohn Disease; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Immunosuppressive Agents; Maintenance Chemotherapy; Male; Medication Adherence; Mercaptopurine; Middle Aged; Treatment Outcome; Young Adult	2013
Low allopurinol doses are sufficient to optimize azathioprine therapy in inflammatory bowel disease patients with inadequate thiopurine metabolite concentrations. European journal of clinical pharmacology, 2013, Volume: 69, Issue:8 Topics: Adult; Aged; Allopurinol; Azathioprine; Female; Guanine Nucleotides; Humans; Inflammatory Bowel Diseases; Male; Mercaptopurine; Middle Aged; Thionucleotides	2013
Randomized clinical trial: a pilot study comparing efficacy of low-dose azathioprine and allopurinol to azathioprine on clinical outcomes in inflammatory bowel disease. Scandinavian journal of gastroenterology, 2016, Volume: 51, Issue:12 Topics: Adult; Aged; Allopurinol; Azathioprine; Denmark; Drug Therapy, Combination; Feces; Female; Humans; Immunosuppressive Agents; Induction Chemotherapy; Inflammatory Bowel Diseases; Leukocyte L1 Antigen Complex; Male; Methyltransferases; Middle Aged; Pilot Projects; Prospective Studies; Quality of Life; Treatment Outcome; Young Adult	2016
Randomised clinical trial: efficacy, safety and dosage of adjunctive allopurinol in azathioprine/mercaptopurine nonresponders (AAA Study). Alimentary pharmacology & therapeutics, 2018, Volume: 47, Issue:8 Topics: Adolescent; Adult; Allopurinol; Azathioprine; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Male; Mercaptopurine; Middle Aged; Treatment Outcome; Young Adult	2018

Other Studies

110 other study(ies) available for azathioprine and allopurinol

Article	Year
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships. Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16 Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone	2016
[The treatment of hyperuricemia after kidney transplantation]. Schweizerische medizinische Wochenschrift, 1977, Sep-24, Volume: 107, Issue:38 Topics: Allopurinol; Azathioprine; Benzbromarone; Creatinine; Drug Interactions; Female; Humans; Kidney Transplantation; Male; Transplantation, Homologous; Uric Acid; Urinary Calculi	1977
[Hemolysis after combined azathioprine and allopurinol therapy]. Acta medica Austriaca, 1979, Volume: 6, Issue:5 Topics: Adult; Allopurinol; Anemia, Hemolytic; Azathioprine; Drug Therapy, Combination; Female; Humans; Kidney Transplantation; Mercaptopurine; Transplantation, Homologous	1979
[Medullar aplasia due to concomitant use of azathioprine and allopurinol in kidney transplantation. Probable beneficial effects of infusion of leukemic cells]. AMB : revista da Associacao Medica Brasileira, 1976, Volume: 22, Issue:5 Topics: Adult; Allopurinol; Anemia, Aplastic; Azathioprine; Blood Transfusion; Drug Interactions; Humans; Kidney Failure, Chronic; Kidney Transplantation; Leukemia, Myeloid; Leukocytes; Male; Transplantation, Homologous	1976
[Pancytopenia following a combination therapy with allopurinol and azathioprine. Discussion contribution and conclusion]. Die Medizinische Welt, 1977, Jan-28, Volume: 28, Issue:4 Topics: Allopurinol; Azathioprine; Drug Therapy, Combination; Humans; Male; Middle Aged; Pancytopenia	1977
Oxypurine and 6-thiopurine nucleoside triphosphate formation in human erythrocytes. Advances in experimental medicine and biology, 1977, Volume: 76A Topics: Allopurinol; Azathioprine; Erythrocytes; Humans; Inosine Nucleotides; Mercaptopurine; Methionine; Methylation; Purine Nucleotides; Sulfhydryl Compounds; Thioinosine; Thionucleotides; Xanthines	1977
[Pancytopenia following combination treatment with allopurinol and azathioprine]. Die Medizinische Welt, 1976, Aug-13, Volume: 27, Issue:33 Topics: Allopurinol; Anemia, Aplastic; Azathioprine; Drug Interactions; Drug Therapy, Combination; Gout; Humans; Male; Middle Aged	1976
[Regulation of purine metabolism and its modification by drugs]. Deutsche medizinische Wochenschrift (1946), 1975, Jan-31, Volume: 100, Issue:5 Topics: Allopurinol; Antimetabolites; Azathioprine; Benzofurans; Chemical Phenomena; Chemistry; Erythrocytes; Folic Acid Antagonists; Glutamine; Gout; Humans; Metabolic Clearance Rate; Methotrexate; Purines; Time Factors; Transferases; Xanthine Oxidase	1975
Allopurinol-azathioprine interaction. Journal of internal medicine, 1991, Volume: 229, Issue:4 Topics: Aged; Allopurinol; Azathioprine; Drug Interactions; Hematologic Diseases; Humans; Male; Middle Aged	1991
Cyclosporine-induced hyperuricemia and gout. The New England journal of medicine, 1990, Feb-01, Volume: 322, Issue:5 Topics: Allopurinol; Azathioprine; Cyclosporins; Drug Interactions; Gout; Humans; Transplantation, Homologous; Uric Acid	1990
Azathioprine and allopurinol: a potentially dangerous combination. Journal of internal medicine, 1990, Volume: 228, Issue:1 Topics: Adolescent; Adult; Allopurinol; Azathioprine; Bone Marrow Diseases; Drug Interactions; Female; Humans; Kidney Transplantation; Leukocyte Count; Male; Middle Aged; Platelet Count	1990
Rheumatoid arthritis refractory to standard therapy. JAMA, 1988, Sep-02, Volume: 260, Issue:9 Topics: Allopurinol; Arthritis, Rheumatoid; Azathioprine; Drug Therapy, Combination; Humans; Liver	1988
[Life-threatening interaction between azathioprine and allopurinol]. Der Internist, 1985, Volume: 26, Issue:11 Topics: Allopurinol; Azathioprine; Chemical and Drug Induced Liver Injury; Drug Synergism; Drug Therapy, Combination; Graft Rejection; Hemolysis; Humans; Kidney Transplantation; Male; Middle Aged; Pancreatitis; Pancytopenia; Postoperative Complications; Uric Acid	1985
Azathioprine toxicity in neuromuscular disease. Neurology, 1986, Volume: 36, Issue:1 Topics: Allopurinol; Azathioprine; Drug Therapy, Combination; Female; Hematologic Diseases; Humans; Leukopenia; Liver; Male; Neuromuscular Diseases; Time Factors	1986
Metabolic side-effects of allopurinol. Progress in biochemical pharmacology, 1974, Volume: 9 Topics: Allopurinol; Antipyrine; Azathioprine; Azauridine; Benzothiadiazines; Dicumarol; Diuretics; Drug Synergism; Erythrocytes; Humans; Leukocytes; Mercaptopurine; Orotic Acid; Pentosyltransferases; Pyrimidines; Sodium Chloride Symporter Inhibitors; Thymidine; Xanthine Oxidase	1974
Skin tumours in immunosuppressed patients. The Australian and New Zealand journal of surgery, 1973, Volume: 43, Issue:3 Topics: Adolescent; Adult; Allopurinol; Antineoplastic Agents; Azathioprine; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cyclophosphamide; Facial Neoplasms; Female; Hand; Humans; Immunosuppressive Agents; Keratoacanthoma; Keratosis; Kidney Transplantation; Leg; Lip Neoplasms; Male; Middle Aged; Nose Neoplasms; Postoperative Complications; Skin Neoplasms; Transplantation, Homologous	1973
Letter: Azathioprine and allopurinol. Annals of internal medicine, 1974, Volume: 80, Issue:3 Topics: Allopurinol; Azathioprine; Drug Interactions; Humans	1974
Clinicopathologic conference: hypertension and the lupus syndrome--revisited. The American journal of medicine, 1971, Volume: 51, Issue:6 Topics: Allopurinol; Azathioprine; Blood Cell Count; Bone Marrow; Bone Marrow Diseases; Drug Interactions; Humans; Hypertension; Kidney Diseases; Male; Middle Aged	1971
Microangiopathic hemolytic anemia in Wegener's granulomatosis. The American journal of medicine, 1971, Volume: 51, Issue:4 Topics: Allopurinol; Anemia, Hemolytic; Azathioprine; Granulomatosis with Polyangiitis; Heparin; Humans; Male; Microcirculation; Middle Aged; Prednisone; Remission, Spontaneous; Thrombophlebitis	1971
Chemotherapy of experimental allergic encephalomyelitis (EAE). Archives internationales de pharmacodynamie et de therapie, 1969, Volume: 179, Issue:2 Topics: Allopurinol; Aminocaproates; Analgesics; Animals; Antineoplastic Agents; Azathioprine; Body Weight; Chloroquine; Colchicine; Cortisone; Cyclophosphamide; Cyproheptadine; Diazoxide; Dimethyl Sulfoxide; Encephalomyelitis, Autoimmune, Experimental; Hydrocortisone; Immunosuppressive Agents; Male; Mercaptopurine; Methotrexate; Methyldopa; Nialamide; Oils; Organ Size; Rats; Strychnine; Talc; Thalidomide; Thioguanine; Thiomalates	1969
Clinical and therapeutic aspects of the Lesch-Nyhan syndrome in Japanese children. Neuropadiatrie, 1970, Volume: 2, Issue:1 Topics: Allopurinol; Athetosis; Azathioprine; Benzofurans; Child; Child, Preschool; Guanine; Humans; Hypoxanthines; Intellectual Disability; Japan; Ketones; Lesch-Nyhan Syndrome; Male; Paraplegia; Pentosyltransferases; Phenols; Purine-Pyrimidine Metabolism, Inborn Errors; Self Mutilation; Spasm; Uric Acid; Xanthines	1970
6-thiopurines as substrates and inhibitors of purine oxidases: a pathway for conversion of azathioprine into 6-thiouric acid without release of 6-mercaptopurine. The Australian journal of experimental biology and medical science, 1969, Volume: 47, Issue:2 Topics: Alkanes; Animals; Azathioprine; Cattle; Chemical Phenomena; Chemistry; Glutathione; Humans; Liver; Mercaptopurine; Milk; Oxidoreductases; Rabbits; Uric Acid; Xanthine Oxidase	1969
Biochemical evidence for a distinct type of primary gout. Nature, 1967, Mar-18, Volume: 213, Issue:5081 Topics: Adolescent; Allopurinol; Azathioprine; Carbon; Carbon Isotopes; Enzymes; Glycine; Gout; Humans; Hypoxanthines; Male; Purines; Uric Acid; Xanthine Oxidase; Xanthines	1967
Chronic granulocytic leukemia after renal transplantation. Archives of internal medicine, 1983, Volume: 143, Issue:10 Topics: Adult; Allopurinol; Azathioprine; Humans; Hydroxyurea; Kidney Transplantation; Leukemia, Myeloid; Male; Melphalan; Postoperative Complications; Prednisone	1983
Azathioprine metabolism in kidney transplant recipients. British journal of clinical pharmacology, 1984, Volume: 18, Issue:5 Topics: Adult; Allopurinol; Azathioprine; Dose-Response Relationship, Drug; Female; Guanine Nucleotides; Humans; Individuality; Kidney Transplantation; Leukocyte Count; Leukopenia; Male; Sex Factors; Thionucleotides	1984
[Drug interference complicates therapy of kidney transplantation patients]. Lakartidningen, 1982, Dec-22, Volume: 79, Issue:51 Topics: Adult; Allopurinol; Azathioprine; Drug Interactions; Humans; Kidney Transplantation; Male	1982
Azathioprine-associated pulmonary dysfunction. Chest, 1983, Volume: 83, Issue:4 Topics: Adult; Allopurinol; Azathioprine; Crohn Disease; Humans; Inflammation; Kidney Calculi; Lung Diseases; Male; Pulmonary Alveoli	1983
Interaction of allopurinol with 6-mercaptopurine and azathioprine. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 1982, Volume: 36, Issue:4 Topics: Aged; Allopurinol; Azathioprine; Blood Cell Count; Bone Marrow; Drug Interactions; Humans; Male; Mercaptopurine; Prednisone; Time Factors	1982
[Causes of the preferential action of imuran on the viability and proliferative activity of a Chinese hamster cell culture in the stationary growth phase]. Tsitologiia, 1980, Volume: 22, Issue:11 Topics: Allopurinol; Animals; Antimetabolites; Azathioprine; Cell Division; Cell Survival; Cells, Cultured; Cricetinae; Cricetulus; Enzyme Activation; Mercaptopurine; Purines; Xanthine Oxidase	1980
A study of the immunosuppressive effect of allopurinol. Immunological communications, 1980, Volume: 9, Issue:1 Topics: Allopurinol; Animals; Azathioprine; Dogs; Dose-Response Relationship, Immunologic; Drug Synergism; Graft Survival; Immune Tolerance; Leukocyte Count; Lymphocytes; Male; Mice; Mice, Inbred A; Mice, Inbred DBA; Skin Transplantation	1980
[Myelosuppression with macrocytic anaemia and leucopenia during treatment with azathioprine in myasthenia gravis]. Deutsche medizinische Wochenschrift (1946), 1982, Oct-22, Volume: 107, Issue:42 Topics: Allopurinol; Anemia, Macrocytic; Azathioprine; Drug Interactions; Female; Humans; Leukopenia; Middle Aged; Myasthenia Gravis	1982
[Use of immunosuppresive agents in the treatment of kidney diseases. Drug therapy of uremia and kidney calculi]. Przeglad lekarski, 1982, Volume: 39, Issue:7 Topics: Allopurinol; Azathioprine; Benzothiadiazines; Cyclophosphamide; Diuretics; Glucocorticoids; Humans; Kidney Calculi; Kidney Diseases; Penicillamine; Phosphates; Sodium Chloride Symporter Inhibitors; Uremia	1982
Increased danger of bone marrow damage in simultaneous azathioprine-allopurinol therapy. International journal of clinical pharmacology, therapy, and toxicology, 1981, Volume: 19, Issue:3 Topics: Adult; Allopurinol; Azathioprine; Bone Marrow Diseases; Drug Therapy, Combination; Female; Humans	1981
Cyclosporine-induced hyperuricemia and gout in renal transplants. Transplantation proceedings, 1995, Volume: 27, Issue:5 Topics: Adult; Allopurinol; Azathioprine; Cyclosporine; Drug Interactions; Gout; Gout Suppressants; Humans; Immunosuppressive Agents; Kidney Transplantation; Uric Acid	1995
[Hematotoxicity caused by azathioprine genetically determined and aggravated by xanthine oxidase deficiency in a patient following renal transplantation]. Presse medicale (Paris, France : 1983), 1995, Jun-10, Volume: 24, Issue:21 Topics: Azathioprine; Female; Humans; Immune Tolerance; Kidney Diseases; Kidney Transplantation; Leukopenia; Middle Aged; Postoperative Complications; Xanthine Oxidase	1995
The interaction between allopurinol and azathioprine. Journal of internal medicine, 1993, Volume: 233, Issue:5 Topics: Allopurinol; Azathioprine; Drug Interactions; Humans	1993
Myelosuppression associated with azathioprine-allopurinol interaction after heart and lung transplantation. Transplantation, 1996, Jun-15, Volume: 61, Issue:11 Topics: Adult; Aged; Allopurinol; Azathioprine; Bone Marrow; Drug Interactions; Gout Suppressants; Heart Transplantation; Heart-Lung Transplantation; Humans; Immunosuppressive Agents; Lung Transplantation; Middle Aged; Retrospective Studies	1996
Azathioprine pharmacogenetics: the relationship between 6-thioguanine nucleotides and thiopurine methyltransferase in patients after heart and kidney transplantation. European journal of clinical chemistry and clinical biochemistry : journal of the Forum of European Clinical Chemistry Societies, 1996, Volume: 34, Issue:3 Topics: Azathioprine; Chromatography, High Pressure Liquid; DNA; Erythrocytes; Female; Guanine Nucleotides; Heart Transplantation; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Methyltransferases; Pharmacogenetics; Polymorphism, Genetic; Radioimmunoassay; Thionucleotides; White People; Xanthine Oxidase	1996
Stability of acetazolamide, allopurinol, azathioprine, clonazepam, and flucytosine in extemporaneously compounded oral liquids. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 1996, Aug-15, Volume: 53, Issue:16 Topics: Acetazolamide; Allopurinol; Azathioprine; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Clonazepam; Drug Combinations; Drug Compounding; Drug Incompatibility; Drug Stability; Flucytosine; Hydrogen-Ion Concentration; Solutions; Temperature	1996
Azathioprine and allopurinol: the price of an avoidable drug interaction. The Annals of pharmacotherapy, 1996, Volume: 30, Issue:9 Topics: Allopurinol; Azathioprine; Cost of Illness; Drug Interactions; Gout Suppressants; Heart Transplantation; Humans; Immunosuppressive Agents; Male; Middle Aged; Pancytopenia; Quality of Life	1996
Treatment of gout after transplantation. British journal of rheumatology, 1998, Volume: 37, Issue:5 Topics: Allopurinol; Azathioprine; Cyclosporine; Diuretics; Drug Interactions; Furosemide; Gout; Gout Suppressants; Heart Transplantation; Humans; Postoperative Complications; Uric Acid	1998
Determination of 6-thioguanine and 6-methylmercaptopurine metabolites in renal transplantation recipients and patients with glomerulonephritis treated with azathioprine. Therapeutic drug monitoring, 1999, Volume: 21, Issue:2 Topics: Adult; Allopurinol; Antimetabolites; Azathioprine; Erythrocytes; Female; Glomerulonephritis; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Mercaptopurine; Middle Aged; Thioguanine	1999
Caffeine metabolism before and after liver transplantation. International journal of clinical pharmacology and therapeutics, 2001, Volume: 39, Issue:2 Topics: Adult; Aged; Aryl Hydrocarbon Hydroxylases; Azathioprine; Caffeine; Case-Control Studies; Cyclosporine; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2A6; Cytochrome P-450 Enzyme System; Female; Humans; Immunosuppressive Agents; Liver; Liver Function Tests; Liver Transplantation; Male; Middle Aged; Mixed Function Oxygenases; Reference Values; Uracil; Xanthine Oxidase	2001
Uric acid or urate nephropathy? American journal of kidney diseases : the official journal of the National Kidney Foundation, 2001, Volume: 38, Issue:2 Topics: Allopurinol; Azathioprine; Biopsy; Diagnosis, Differential; Drug Interactions; Humans; Kidney; Kidney Diseases; Mycophenolic Acid; Uric Acid	2001
Long-term efficacy of hyperuricaemia treatment in renal transplant patients. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2003, Volume: 18, Issue:3 Topics: Adolescent; Adult; Aged; Allopurinol; Antimetabolites; Azathioprine; Child; Cohort Studies; Female; Follow-Up Studies; Humans; Hyperuricemia; Kidney Failure, Chronic; Kidney Transplantation; Male; Middle Aged; Retrospective Studies; Time Factors	2003
Toxicity of low dose azathioprine and 6-mercaptopurine in rat hepatocytes. Roles of xanthine oxidase and mitochondrial injury. Journal of hepatology, 2004, Volume: 40, Issue:3 Topics: Adenosine Triphosphate; Allopurinol; Animals; Antioxidants; Azathioprine; Cell Differentiation; Cell Survival; Cells, Cultured; Chromans; Enzyme Inhibitors; Glutathione; Glutathione Disulfide; Hepatocytes; Male; Mercaptopurine; Microscopy, Electron; Mitochondria, Liver; Necrosis; Oxidative Stress; Rats; Rats, Wistar; Time Factors; Xanthine Oxidase	2004
[Panzytopenia from combination therapy with azathioprin and allopurinol]. Zeitschrift fur Rheumatologie, 2004, Volume: 63, Issue:5 Topics: Aged; Allopurinol; Antirheumatic Agents; Autoantibodies; Azathioprine; Blood Cell Count; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Dose-Response Relationship, Drug; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Erythrocyte Count; Female; Gout Suppressants; Hematopoiesis; Humans; Hyperuricemia; Lupus Erythematosus, Systemic; Pancytopenia	2004
Allopurinol safely and effectively optimizes tioguanine metabolites in inflammatory bowel disease patients not responding to azathioprine and mercaptopurine. Alimentary pharmacology & therapeutics, 2005, Sep-01, Volume: 22, Issue:5 Topics: Allopurinol; Antimetabolites; Azathioprine; Drug Combinations; Drug Resistance; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Mercaptopurine; Thioguanine	2005
Observations on the use of allopurinol in combination with azathioprine or mercaptopurine. Alimentary pharmacology & therapeutics, 2005, Volume: 22, Issue:11-12 Topics: Allopurinol; Antimetabolites; Azathioprine; Drug Combinations; Drug Synergism; Humans; Inflammatory Bowel Diseases; Mercaptopurine; Thioguanine	2005
Case 9: initiation of urate-lowering therapy for advanced gout complicated by chronic renal insufficiency. The American journal of medicine, 2006, Volume: 119, Issue:11 Suppl 1 Topics: Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Contraindications; Drug Interactions; Gout; Gout Suppressants; Humans; Hypertension; Hyperuricemia; Immunosuppressive Agents; Male; Middle Aged; Renal Insufficiency, Chronic	2006
A nudge in the right direction: shaping the metabolic fate of thiopurines for therapeutic gain. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2007, Volume: 5, Issue:2 Topics: Allopurinol; Azathioprine; Drug Synergism; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Mercaptopurine	2007
Effect of allopurinol on clinical outcomes in inflammatory bowel disease nonresponders to azathioprine or 6-mercaptopurine. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2007, Volume: 5, Issue:2 Topics: Allopurinol; Azathioprine; Drug Synergism; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Mercaptopurine; Thioguanine; Treatment Outcome	2007
The role of xanthine oxidase in thiopurine metabolism: a case report. Therapeutic drug monitoring, 2007, Volume: 29, Issue:6 Topics: Azathioprine; Female; Humans; Mercaptopurine; Middle Aged; Pancreatitis, Chronic; Xanthine Oxidase	2007
Influence of xanthine oxidase on thiopurine metabolism in Crohn's disease. Alimentary pharmacology & therapeutics, 2008, Sep-15, Volume: 28, Issue:6 Topics: Adult; Biological Availability; Case-Control Studies; Crohn Disease; Female; Humans; Immunosuppressive Agents; Intestine, Small; Mercaptopurine; Methyltransferases; Uric Acid; Xanthine Oxidase	2008
Inflammatory bowel disease potpourri: a vignette-based discussion. Medicine and health, Rhode Island, 2009, Volume: 92, Issue:4 Topics: Adult; Allopurinol; Azathioprine; Clostridioides difficile; Colitis, Ulcerative; Crohn Disease; Drug Interactions; Drug Therapy, Combination; Enterocolitis, Pseudomembranous; Female; Gout; Gout Suppressants; Histoplasmosis; Humans; Immunosuppressive Agents; Male; Mercaptopurine; Middle Aged; Psoas Abscess; Tumor Necrosis Factor-alpha	2009
Novel pharmacogenetic markers for treatment outcome in azathioprine-treated inflammatory bowel disease. Alimentary pharmacology & therapeutics, 2009, Aug-15, Volume: 30, Issue:4 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alcohol Oxidoreductases; Aldehyde Oxidase; Azathioprine; Cohort Studies; Female; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Male; Methyltransferases; Middle Aged; Polymerase Chain Reaction; Polymorphism, Genetic; Statistics as Topic; Treatment Outcome; Xanthine Dehydrogenase; Xanthine Oxidase; Young Adult	2009
Low-dose azathioprine or mercaptopurine in combination with allopurinol can bypass many adverse drug reactions in patients with inflammatory bowel disease. Alimentary pharmacology & therapeutics, 2010, Volume: 31, Issue:6 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Allopurinol; Azathioprine; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; London; Male; Mercaptopurine; Middle Aged; Queensland; Retrospective Studies; Treatment Outcome	2010
Gout in pediatric renal transplant recipients. Pediatric nephrology (Berlin, Germany), 2010, Volume: 25, Issue:12 Topics: Adolescent; Allopurinol; Arthritis, Gouty; Azathioprine; Biopsy; Child; Gout Suppressants; Humans; Immunosuppressive Agents; Kidney Transplantation; Magnetic Resonance Imaging; Male; Treatment Outcome	2010
IBD: Switching metabolism-can two drugs be better than one? Nature reviews. Gastroenterology & hepatology, 2010, Volume: 7, Issue:8 Topics: Allopurinol; Antimetabolites; Azathioprine; Drug Therapy, Combination; Humans; Inflammatory Bowel Diseases; Mercaptopurine	2010
Allopurinol-thiopurine combination therapy in inflammatory bowel disease: are there genetic clues to this puzzle? Pharmacogenomics, 2010, Volume: 11, Issue:11 Topics: Allopurinol; Azathioprine; Biotransformation; Chemical and Drug Induced Liver Injury; Drug Therapy, Combination; Humans; Inflammatory Bowel Diseases; Mercaptopurine; Polymorphism, Genetic; Xanthine Oxidase	2010
Combination of thiopurines and allopurinol: adverse events and clinical benefit in IBD. Journal of Crohn's & colitis, 2010, Volume: 4, Issue:4 Topics: Adult; Allopurinol; Azathioprine; Colitis, Ulcerative; Crohn Disease; Drug Therapy, Combination; Female; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Male; Mercaptopurine; Middle Aged; Opportunistic Infections; Retrospective Studies; Young Adult	2010
Allopurinol might improve response to azathioprine and 6-mercaptopurine by correcting an unfavorable metabolite ratio. Journal of gastroenterology and hepatology, 2011, Volume: 26, Issue:1 Topics: Adult; Allopurinol; Anti-Inflammatory Agents; Azathioprine; Biotransformation; Drug Therapy, Combination; Enzyme Inhibitors; Erythrocyte Count; Female; Gastrointestinal Agents; Guanine Nucleotides; Humans; Inflammatory Bowel Diseases; Male; Mercaptopurine; Middle Aged; New Zealand; Red-Cell Aplasia, Pure; Retrospective Studies; Steroids; Thionucleotides; Time Factors; Treatment Outcome; Xanthine Oxidase	2011
How are thiopurines used and monitored by Swedish gastroenterologists when treating patients with inflammatory bowel disease? Scandinavian journal of gastroenterology, 2011, Volume: 46, Issue:10 Topics: Allopurinol; Antibodies, Monoclonal; Antimetabolites; Azathioprine; Drug Therapy, Combination; Female; Gastroenterology; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Male; Methyltransferases; Mycophenolic Acid; Practice Patterns, Physicians'; Surveys and Questionnaires; Sweden; Tacrolimus; Thioguanine; Tumor Necrosis Factor-alpha	2011
Optimising outcome on thiopurines in inflammatory bowel disease by co-prescription of allopurinol. Journal of Crohn's & colitis, 2012, Volume: 6, Issue:9 Topics: Adult; Aged; Aged, 80 and over; Allopurinol; Azathioprine; Chemical and Drug Induced Liver Injury; Colitis, Ulcerative; Crohn Disease; Drug Therapy, Combination; Enzyme Inhibitors; Female; Humans; Immunosuppressive Agents; Male; Mercaptopurine; Methyltransferases; Middle Aged; Purine Nucleotides; Retrospective Studies; Statistics, Nonparametric; Thioguanine; Treatment Outcome; Young Adult	2012
A skewed thiopurine metabolism is a common clinical phenomenon that can be successfully managed with a combination of low-dose azathioprine and allopurinol. Journal of Crohn's & colitis, 2013, Volume: 7, Issue:6 Topics: Adult; Allopurinol; Azathioprine; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Drug Resistance; Erythrocytes; Female; Free Radical Scavengers; Genotype; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Male; Methyltransferases; Middle Aged; Thioguanine	2013
Effect of genetic polymorphisms on effectiveness of low-dose azathioprine in Japanese patients with systemic lupus erythematosus. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2012, Dec-01, Volume: 69, Issue:23 Topics: Adolescent; Adult; Aged; Asian People; Azathioprine; Female; Genotype; Humans; Immunosuppressive Agents; IMP Dehydrogenase; Lupus Erythematosus, Systemic; Male; Middle Aged; Multidrug Resistance-Associated Proteins; Polymorphism, Single Nucleotide; Pyrophosphatases; Retrospective Studies; Severity of Illness Index; Xanthine Oxidase	2012
Use of a xanthine oxidase inhibitor in autoimmune hepatitis. Hepatology (Baltimore, Md.), 2013, Volume: 57, Issue:3 Topics: Allopurinol; Azathioprine; Enzyme Inhibitors; Female; Glucocorticoids; Hepatitis, Autoimmune; Humans; Immunosuppressive Agents; Middle Aged; Prednisolone; Treatment Outcome; Xanthine Oxidase	2013
[Myelotoxicity due to interaction between azathioprine and allopurinol in a patient with Crohn's disease]. Gastroenterologia y hepatologia, 2013, Volume: 36, Issue:4 Topics: Aged; Allopurinol; Azathioprine; Biotransformation; Bone Marrow Diseases; Crohn Disease; Drug Interactions; Humans; Immunosuppressive Agents; Male; Mercaptopurine; Methyltransferases; Xanthine Oxidase	2013
The effect of allopurinol and low-dose thiopurine combination therapy on the activity of three pivotal thiopurine metabolizing enzymes: results from a prospective pharmacological study. Journal of Crohn's & colitis, 2013, Volume: 7, Issue:10 Topics: Adult; Allopurinol; Azathioprine; Drug Therapy, Combination; Enzyme Activation; Enzyme Inhibitors; Fatigue; Female; Guanine Nucleotides; Humans; Hypoxanthine Phosphoribosyltransferase; Immunosuppressive Agents; Inflammatory Bowel Diseases; Male; Mercaptopurine; Methyltransferases; Middle Aged; Nausea; Prospective Studies; Thioinosine; Thionucleotides; Xanthine Oxidase	2013
Allopurinol safely and effectively optimises thiopurine metabolites in patients with autoimmune hepatitis. Alimentary pharmacology & therapeutics, 2013, Volume: 37, Issue:6 Topics: Adult; Aged; Alanine Transaminase; Allopurinol; Antimetabolites; Drug Interactions; Drug Therapy, Combination; Female; Hepatitis, Autoimmune; Humans; Male; Mercaptopurine; Methyltransferases; Middle Aged; Salvage Therapy; Thioguanine	2013
Sustained improvement of cardiac function with immunosuppressive therapy in a case of acute lymphocytic myocarditis secondary to allopurinol induced Stevens-Johnson syndrome. Delaware medical journal, 2012, Volume: 84, Issue:12 Topics: Adrenal Cortex Hormones; Aged; Allopurinol; Antimetabolites; Azathioprine; Drug Therapy, Combination; Female; Heart; Humans; Immunosuppressive Agents; Magnetic Resonance Imaging; Myocarditis; Stevens-Johnson Syndrome	2012
Mechanism of allopurinol induced TPMT inhibition. Biochemical pharmacology, 2013, Aug-15, Volume: 86, Issue:4 Topics: Adult; Allopurinol; Azathioprine; Case-Control Studies; Drug Therapy, Combination; Erythrocytes; Female; Humans; Inflammatory Bowel Diseases; Male; Mercaptopurine; Methyltransferases; Oxypurinol; Prospective Studies; Xanthines	2013
Involvement of oxidative stress and immune- and inflammation-related factors in azathioprine-induced liver injury. Toxicology letters, 2014, Jan-13, Volume: 224, Issue:2 Topics: Animals; Azathioprine; Carrier Proteins; Chemical and Drug Induced Liver Injury; Female; Glutathione; Immunity, Innate; Inflammation; Mice; Mice, Inbred BALB C; NLR Family, Pyrin Domain-Containing 3 Protein; Oxidative Stress; Tumor Necrosis Factor-alpha; Xanthine Oxidase	2014
An integrated proteomic and transcriptomic approach to understanding azathioprine- induced hepatotoxicity in rat primary hepatocytes. Electrophoresis, 2014, Volume: 35, Issue:6 Topics: Animals; Azathioprine; Cell Survival; Gene Expression Profiling; Hepatocytes; Male; Mitogen-Activated Protein Kinase Kinases; Proteome; Proteomics; Rats; Rats, Sprague-Dawley; RNA, Messenger; Up-Regulation; Xanthine Oxidase	2014
Febuxostat as a novel option to optimize thiopurines' metabolism in patients with inadequate metabolite levels. The Annals of pharmacotherapy, 2014, Volume: 48, Issue:5 Topics: Adult; Azathioprine; Drug Interactions; Enzyme Inhibitors; Febuxostat; Female; Guanine Nucleotides; Humans; Immunosuppressive Agents; Mercaptopurine; Muscular Diseases; Thiazoles; Thionucleotides; Xanthine Oxidase	2014
Treatment of gout in a renal transplant patient leading to severe thrombocytopenia. Journal of clinical pharmacy and therapeutics, 2014, Volume: 39, Issue:5 Topics: Aged; Allopurinol; Azathioprine; Diagnosis, Differential; Female; Gout; Gout Suppressants; Humans; Immunosuppressive Agents; Kidney Transplantation; Severity of Illness Index; Thrombocytopenia	2014
Evaluation of azathioprine-induced cytotoxicity in an in vitro rat hepatocyte system. BioMed research international, 2014, Volume: 2014 Topics: Allopurinol; Animals; Azathioprine; Glutathione; Graft Rejection; Hepatocytes; Humans; Hydrogen Peroxide; Membrane Potential, Mitochondrial; Organ Transplantation; Oxidative Stress; Rats; Reactive Oxygen Species	2014
Allopurinol and 5-aminosalicylic acid influence thiopurine-induced hepatotoxicity in vitro. Cell biology and toxicology, 2015, Volume: 31, Issue:3 Topics: Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Antimetabolites; Azathioprine; Cell Line, Tumor; Hepatocytes; Humans; Mercaptopurine; Mesalamine	2015
Successful Pregnancies with Thiopurine-Allopurinol Co-Therapy for Inflammatory Bowel Disease. Journal of Crohn's & colitis, 2015, Volume: 9, Issue:8 Topics: Adult; Allopurinol; Azathioprine; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Mercaptopurine; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Retrospective Studies; Treatment Outcome	2015
Clinical Value of Mercaptopurine After Failing Azathioprine Therapy in Patients With Inflammatory Bowel Disease. Therapeutic drug monitoring, 2016, Volume: 38, Issue:4 Topics: Adolescent; Adult; Allopurinol; Azathioprine; Female; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Male; Mercaptopurine; Retrospective Studies; Young Adult	2016
Long-term Safety and Efficacy of Low-dose Azathioprine and Allopurinol Cotherapy in Inflammatory Bowel Disease: A Large Observational Study. Inflammatory bowel diseases, 2016, Volume: 22, Issue:7 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Allopurinol; Antimetabolites; Azathioprine; Blood Sedimentation; C-Reactive Protein; Chemical and Drug Induced Liver Injury; Colitis, Ulcerative; Crohn Disease; Drug Therapy, Combination; Female; Hematologic Diseases; Humans; Immunosuppressive Agents; Intestinal Mucosa; Male; Methyltransferases; Middle Aged; Retrospective Studies; Treatment Outcome; Young Adult	2016
Azathioprine with Allopurinol: Lower Deoxythioguanosine in DNA and Transcriptome Changes Indicate Mechanistic Differences to Azathioprine Alone. Inflammatory bowel diseases, 2017, Volume: 23, Issue:6 Topics: Allopurinol; Azathioprine; Biomarkers; Deoxyguanosine; DNA; Drug Therapy, Combination; Gene Expression; Gene Expression Profiling; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Leukocyte Count; Methyltransferases; Pilot Projects; United Kingdom	2017
Optimizing Thiopurine Therapy in Inflammatory Bowel Disease Among 2 Real-life Intercept Cohorts: Effect of Allopurinol Comedication? Inflammatory bowel diseases, 2017, Volume: 23, Issue:11 Topics: Adult; Allopurinol; Azathioprine; Drug Monitoring; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Male; Mercaptopurine; Middle Aged; Retrospective Studies; Thioguanine; Treatment Outcome; Young Adult	2017
Allopurinol Co-prescription Improves the Outcome of Azathioprine Treatment in Chronic Eczema. Acta dermato-venereologica, 2018, Mar-13, Volume: 98, Issue:3 Topics: Adult; Allopurinol; Azathioprine; Chronic Disease; Dermatitis, Atopic; Drug Therapy, Combination; Eczema; Female; Foot Dermatoses; Guanine Nucleotides; Hand Dermatoses; Humans; Immunosuppressive Agents; Male; Mercaptopurine; Middle Aged; Prospective Studies; Thionucleotides; Time Factors; Treatment Outcome	2018
Low-dose thiopurine with allopurinol co-therapy overcomes thiopurine intolerance and allows thiopurine continuation in inflammatory bowel disease. Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2018, Volume: 50, Issue:7 Topics: Adolescent; Adult; Aged; Allopurinol; Australia; Azathioprine; Chemical and Drug Induced Liver Injury; Drug Therapy, Combination; Fatigue; Female; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Linear Models; Male; Middle Aged; Retrospective Studies; Treatment Outcome; Young Adult	2018
Thiopurine Optimization Through Combination With Allopurinol in Children With Inflammatory Bowel Diseases. Journal of pediatric gastroenterology and nutrition, 2018, Volume: 67, Issue:3 Topics: Adolescent; Adult; Allopurinol; Azathioprine; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Follow-Up Studies; Free Radical Scavengers; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Male; Mercaptopurine; Retrospective Studies; Treatment Outcome; Young Adult	2018
Editorial: an argument for low-dose thiopurine allopurinol combination use as first-line therapy in inflammatory bowel disease-authors' reply. Alimentary pharmacology & therapeutics, 2018, Volume: 48, Issue:1 Topics: Allopurinol; Azathioprine; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Mercaptopurine	2018
Editorial: an argument for low-dose thiopurine allopurinol combination use as first-line therapy in inflammatory bowel disease. Alimentary pharmacology & therapeutics, 2018, Volume: 48, Issue:1 Topics: Allopurinol; Azathioprine; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Mercaptopurine	2018
Thiopurine-induced toxicity is associated with dysfunction variant of the human molybdenum cofactor sulfurase gene (xanthinuria type II). Toxicology and applied pharmacology, 2018, 08-15, Volume: 353 Topics: Adult; Aldehyde Oxidase; Female; Humans; Mercaptopurine; Methyltransferases; Polymorphism, Genetic; Purine-Pyrimidine Metabolism, Inborn Errors; Sulfurtransferases; Uric Acid; Xanthine; Xanthine Dehydrogenase; Xanthine Oxidase	2018
Lower 6-MMP/6-TG Ratio May Be a Therapeutic Target in Pediatric Autoimmune Hepatitis. Journal of pediatric gastroenterology and nutrition, 2018, Volume: 67, Issue:6 Topics: Allopurinol; Antimetabolites; Azathioprine; Child; Female; Guanine Nucleotides; Hepatitis, Autoimmune; Humans; Liver Function Tests; Maintenance Chemotherapy; Male; Mercaptopurine; Retrospective Studies; Thionucleotides; Treatment Outcome	2018
Outcome of concomitant treatment with thiopurines and allopurinol in patients with inflammatory bowel disease: A nationwide Danish cohort study. United European gastroenterology journal, 2020, Volume: 8, Issue:1 Topics: Adult; Allopurinol; Azathioprine; Colitis, Ulcerative; Crohn Disease; Denmark; Drug Therapy, Combination; Female; Follow-Up Studies; Hospitalization; Humans; Immunosuppressive Agents; Male; Mercaptopurine; Middle Aged; Remission Induction; Severity of Illness Index; Signal Transduction; Thioguanine; Treatment Outcome	2020
Limited added value of laboratory monitoring in thiopurine maintenance monotherapy in inflammatory bowel disease patients. Alimentary pharmacology & therapeutics, 2020, Volume: 51, Issue:12 Topics: Adult; Allopurinol; Azathioprine; Clinical Laboratory Techniques; Drug Monitoring; Drug-Related Side Effects and Adverse Reactions; Female; Follow-Up Studies; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Maintenance Chemotherapy; Male; Mercaptopurine; Middle Aged; Netherlands; Predictive Value of Tests; Prognosis; Purines; Retrospective Studies; Young Adult	2020
Influence of allopurinol on thiopurine associated toxicity: A retrospective population-based cohort study. British journal of clinical pharmacology, 2021, Volume: 87, Issue:5 Topics: Adult; Allopurinol; Azathioprine; Cohort Studies; Drug Therapy, Combination; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Mercaptopurine; Retrospective Studies; Treatment Outcome	2021
Azathioprine-induced severe anemia potentiated by the concurrent use of allopurinol. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2021, 01-18, Volume: 193, Issue:3 Topics: Allopurinol; Anemia, Aplastic; Azathioprine; Bile Duct Diseases; Erythrocyte Transfusion; Gout Suppressants; Humans; Immunosuppressive Agents; Male; Middle Aged	2021
Xanthine oxidase activity in thiopurine curative Chinese inflammatory bowel disease patients. Pharmacology research & perspectives, 2021, Volume: 9, Issue:3 Topics: Adolescent; Adult; Aged; Asian People; Azathioprine; Child; Child, Preschool; Female; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Leukopenia; Male; Mercaptopurine; Middle Aged; Retrospective Studies; Xanthine Oxidase; Young Adult	2021
Azathioprine with Allopurinol Is a Promising First-Line Therapy for Inflammatory Bowel Diseases. Digestive diseases and sciences, 2022, Volume: 67, Issue:8 Topics: Allopurinol; Azathioprine; Drug Therapy, Combination; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Mercaptopurine; Retrospective Studies; Treatment Outcome	2022
Genotype-Guided Prescription of Azathioprine Reduces the Incidence of Adverse Drug Reactions in TPMT Intermediate Metabolizers to a Similar Incidence as Normal Metabolizers. Advances in therapy, 2022, Volume: 39, Issue:4 Topics: Allopurinol; Azathioprine; Drug-Related Side Effects and Adverse Reactions; Female; Genotype; Humans; Immunosuppressive Agents; Incidence; Methyltransferases; Prescriptions; Retrospective Studies	2022
Low Dose Azathioprine with Allopurinol in IBD: Early Days to Call It a Recipe for Success. Digestive diseases and sciences, 2022, Volume: 67, Issue:8 Topics: Allopurinol; Azathioprine; Drug Therapy, Combination; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Mercaptopurine	2022
Safety and Efficacy of Split-Dose Thiopurine vs Low-Dose Thiopurine-Allopurinol Cotherapy in Pediatric Inflammatory Bowel Disease. Clinical and translational gastroenterology, 2023, 03-01, Volume: 14, Issue:3 Topics: Allopurinol; Azathioprine; Child; Drug Therapy, Combination; Humans; Inflammatory Bowel Diseases; Mercaptopurine; Retrospective Studies; Treatment Outcome	2023