azaspiracid and tetrahydrofuran

azaspiracid has been researched along with tetrahydrofuran* in 1 studies

Other Studies

1 other study(ies) available for azaspiracid and tetrahydrofuran

Article	Year
Synthetic studies toward the C5-C20 domain of the azaspiracids. Organic letters, 2001, Apr-05, Volume: 3, Issue:7 [structure: see text]. An approach toward the C5-C20 THF-fused trioxadispiroketal portion of the azaspiracids is reported. The highly substituted azaspiracid D ring (C16-C19) was prepared by the one-pot conversion of a tetraol into a tetrahydrofuran. Efforts to establish the C10 and C13 spiroketal centers via an oxonium-initiated bis-spiroketalization under both kinetic and thermodynamic conditions have yielded the (10R,13S)-trioxadispiroketal 19 as the major product, which is diastereomeric with the (10R,13R) relative configuration assigned to the azaspiracids. Topics: Animals; Bivalvia; Furans; Humans; Marine Toxins; Molecular Structure; Solvents; Spiro Compounds	2001

Article

Year

Synthetic studies toward the C5-C20 domain of the azaspiracids.

Organic letters, 2001, Apr-05, Volume: 3, Issue:7

[structure: see text]. An approach toward the C5-C20 THF-fused trioxadispiroketal portion of the azaspiracids is reported. The highly substituted azaspiracid D ring (C16-C19) was prepared by the one-pot conversion of a tetraol into a tetrahydrofuran. Efforts to establish the C10 and C13 spiroketal centers via an oxonium-initiated bis-spiroketalization under both kinetic and thermodynamic conditions have yielded the (10R,13S)-trioxadispiroketal 19 as the major product, which is diastereomeric with the (10R,13R) relative configuration assigned to the azaspiracids.

Topics: Animals; Bivalvia; Furans; Humans; Marine Toxins; Molecular Structure; Solvents; Spiro Compounds

2001