azacitidine has been researched along with uridine in 44 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 32 (72.73) | 18.7374 |
| 1990's | 1 (2.27) | 18.2507 |
| 2000's | 2 (4.55) | 29.6817 |
| 2010's | 4 (9.09) | 24.3611 |
| 2020's | 5 (11.36) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Bloch, A | 1 |
| Wentworth, DF; Wolfenden, R | 1 |
| Karon, MR; Lee, TT | 1 |
| Cihák, A; Rada, B | 1 |
| Chabner, BA; Drake, JC; Stoller, RG | 1 |
| Ng, SK; Rogers, J; Sanwal, BD | 1 |
| Abbasi, MM; Beisler, JA; Voytek, P; Wolpert-DeFilippes, MK | 1 |
| Grotzinger, K; McGuire, W; Young, R | 1 |
| Abraham, D; Behrens, M; Plagemann, PG | 1 |
| Gaudio, L; Kelly, CJ; Schoenemann, PT; Wodinsky, I; Yesair, DW | 1 |
| Anderson, EP; Liacouras, AS | 1 |
| Gray, MD; Jesch, SA; Stein, GH | 1 |
| Poirier, LA; Waalkes, MP; Wilson, MJ | 1 |
| Moriconi, WJ; Slavik, M; Taylor, S | 1 |
| Bhagwat, AS; Roberts, RJ | 1 |
| Bernheim, J; Buyssens, N; Cortvrindt, R; Roobol, K | 1 |
| DeSimone, J; Hall, L; Heller, P; Molokie, RE; Zwiers, D | 1 |
| Cerná, J; Cihák, A | 1 |
| Duff, R; Knight, P; Rapp, F | 1 |
| Broucek, J; Cihák, A | 1 |
| Cihák, A; Veselý, J | 2 |
| Cihák, A; Seifertová, M; Sorm, F; Veselý, J | 1 |
| Penman, S; Reichman, M | 1 |
| Cihák, A; Harrap, KR; Veselý, J | 1 |
| Pitot, HC; Weiss, JW | 2 |
| Karon, M; Lee, T; Momparler, RL | 1 |
| Abbasi, MM; Beisler, JA; Glazer, RI; Peale, AL | 1 |
| Cadman, E; Grant, S; Jakubowski, A; Rauscher, F | 1 |
| Cadman, E; Grant, S | 1 |
| Campbell, J; Li, ZR; Rustum, YM | 1 |
| Bhalla, K; Gleyzer, M; Grant, S | 1 |
| Engelbrecher, A; Häuser, R; Titz, B; Uetz, P | 1 |
| Banerjee, D; Bertino, JR; Humeniuk, R; Mishra, PJ | 1 |
| Hosokawa, M; Iwakawa, S; Ueda, K | 1 |
| Hussain, S | 1 |
| Duchmann, M; Itzykson, R | 1 |
| Arrate, M; Azab, M; Boyd, K; Fuller, L; Gorska, AE; Keer, H; Oganesian, A; Ramsey, HE; Savona, MR | 1 |
| H Wei, A; Kipp, D | 1 |
| Cahill, K; Odenike, O; Patel, AA; Saygin, C | 1 |
| Griffiths, EA | 1 |
| Chen, H; de Claro, RA; Earp, J; Ehrlich, LA; Gehrke, BJ; Kim, N; Kitabi, E; Manning, ML; Norsworthy, KJ; Okusanya, OO; Pazdur, R; Subramaniam, S; Vallejo, J | 1 |
4 review(s) available for azacitidine and uridine
| Article | Year |
|---|---|
The structure of nucleosides in relation to their biological and and biochemical activity: a summary.
Topics: 3-Deazauridine; Adenine; Adenosine; Anti-Bacterial Agents; Azacitidine; Cytarabine; Idoxuridine; Isopentenyladenosine; Nucleosides; Pseudouridine; Puromycin; Structure-Activity Relationship; Tubercidin; Uridine | 1975 |
Catalytic crosslinking-based methods for enzyme-specified profiling of RNA ribonucleotide modifications.
Topics: Animals; Azacitidine; Biocatalysis; Cross-Linking Reagents; Escherichia coli Proteins; Fluorouracil; Humans; Immunoprecipitation; Methylation; Methyltransferases; Multienzyme Complexes; Pseudouridine; RNA Processing, Post-Transcriptional; RNA, Messenger; Transcriptome; Uridine | 2019 |
Clinical update on hypomethylating agents.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Clinical Trials as Topic; Decitabine; DNA Methylation; Drug Administration Schedule; Drug Combinations; Gene Expression Regulation, Leukemic; Humans; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Chronic; Myelodysplastic Syndromes; Uridine | 2019 |
Cedazuridine/decitabine: from preclinical to clinical development in myeloid malignancies.
Topics: Azacitidine; Decitabine; Humans; Leukemia, Myelomonocytic, Chronic; Myelodysplastic Syndromes; Uridine | 2021 |
1 trial(s) available for azacitidine and uridine
| Article | Year |
|---|---|
FDA Approval Summary: Decitabine and Cedazuridine Tablets for Myelodysplastic Syndromes.
Topics: Adult; Azacitidine; Decitabine; Humans; Myelodysplastic Syndromes; Tablets; Treatment Outcome; Uridine | 2022 |
39 other study(ies) available for azacitidine and uridine
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
On the interaction of 3,4,5,6-tetrahydrouridine with human liver cytidine deaminase.
Topics: Azacitidine; Binding Sites; Cytarabine; Cytidine Deaminase; Humans; Kinetics; Liver; Nucleoside Deaminases; Protein Binding; Tetrahydrouridine; Uridine | 1975 |
Inhibition of protein synthesis in 5-azacytidine-treated HeLa cells.
Topics: Amino Acyl-tRNA Synthetases; Azacitidine; Cytidine; Depression, Chemical; HeLa Cells; Humans; Neoplasm Proteins; RNA, Neoplasm; RNA, Transfer; Uridine; Valine | 1976 |
Uridine kinase: properties, biological significance and chemotherapeutic aspects (a review).
Topics: Animals; Azacitidine; Azauridine; Molecular Weight; Neoplasms, Experimental; Phosphotransferases; Pyrimidine Nucleosides; Pyrimidines; Species Specificity; Uridine; Uridine Kinase; Virus Diseases | 1976 |
Characteristics of the enzyme uridine-cytidine kinase isolated from a cultured human cell line.
Topics: Azacitidine; Cell Line; Cytidine; Humans; Kinetics; Leukemia, Lymphoid; Phosphotransferases; Uridine; Uridine Kinase | 1977 |
Alterations in differentiation and pyrimidine pathway enzymes in 5-azacytidine resistant variants of a myoblast line.
Topics: Adenosine; Animals; Aspartate Carbamoyltransferase; Azacitidine; Azaguanine; Bromodeoxyuridine; Cell Differentiation; Cell Fusion; Cell Line; Cytarabine; Cytidine Deaminase; Drug Resistance; Genetic Variation; Muscles; Nucleoside Deaminases; Orotate Phosphoribosyltransferase; Orotidine-5'-Phosphate Decarboxylase; Ouabain; Phosphotransferases; Rats; Theophylline; Thymidine; Uridine; Uridine Kinase | 1977 |
Comparative studies of the cytostatic action and metabolism of 5-azacytidine and 5,6-dihydro-5-azacytidine.
Topics: Animals; Azacitidine; Cell Division; Cells, Cultured; Cytidine; Cytidine Deaminase; Deoxycytidine; Drug Synergism; Kinetics; Leukemia L1210; Oxidative Phosphorylation; Tetrahydrouridine; Thymidine; Uridine | 1977 |
Alterations in [3H]thymidine incorporation into DNA and [3H]uridine incorporation into RNA induced by 5-azacytidine in vivo.
Topics: Animals; Ascites; Azacitidine; Bone Marrow; DNA; Female; Intestinal Mucosa; Mice; Mice, Inbred Strains; Neoplasms, Experimental; RNA; Thymidine; Time Factors; Uridine | 1978 |
Metabolism and cytotoxicity of 5-azacytidine in cultured Novikoff rat hepatoma and P388 mouse leukemia cells and their enhancement by preincubation with pyrazofurin.
Topics: Amides; Animals; Antibiotics, Antineoplastic; Azacitidine; Carcinoma, Hepatocellular; Cell Division; Cell Survival; Cytidine; DNA, Neoplasm; Drug Synergism; Leukemia, Experimental; Liver Neoplasms; Neoplasm Proteins; Neoplasms, Experimental; Phosphates; Pyrazoles; Ribonucleosides; Ribose; RNA, Neoplasm; Uridine | 1978 |
Pharmacokinetic considerations in evaluating the effects of tetrahydrouridine on 5-azacytidine chemotherapy in L1210 leukemic mice.
Topics: Animals; Azacitidine; Drug Therapy, Combination; Female; Infusions, Parenteral; Injections, Intraperitoneal; Leukemia L1210; Mice; Tetrahydrouridine; Uridine | 1978 |
Uridine-cytidine kinase. IV. Kinetics of the competition between 5-azacytidine and the two natural substrates.
Topics: Animals; Azacitidine; Cytidine; In Vitro Techniques; Kinetics; Liver Neoplasms, Experimental; Mice; Models, Biological; Phosphotransferases; Substrate Specificity; Uridine; Uridine Kinase | 1979 |
5-Azacytidine-induced demethylation of DNA to senescent level does not block proliferation of human fibroblasts.
Topics: Azacitidine; Cell Division; Cell Line; Cell Line, Transformed; Cell Transformation, Neoplastic; Cellular Senescence; DNA Damage; Fibroblasts; Humans; RNA; Simian virus 40; Uridine | 1991 |
Reduced cadmium-induced cytotoxicity in cultured liver cells following 5-azacytidine pretreatment.
Topics: Animals; Azacitidine; Cadmium; Cadmium Poisoning; DNA; Drug Interactions; In Vitro Techniques; Liver; Metallothionein; Potassium; Rats; Rats, Inbred F344; Thymidine; Tritium; Uridine | 1985 |
3-Deazauridine (NSC 126849): an interesting modulator of biochemical response.
Topics: 3-Deazauridine; Acute Disease; Animals; Antineoplastic Agents; Azacitidine; Cytarabine; Decitabine; Drug Evaluation; Drug Synergism; Galactosamine; Humans; Kinetics; Leukemia; Neoplasms; Thymidine; Uridine | 1986 |
Genetic analysis of the 5-azacytidine sensitivity of Escherichia coli K-12.
Topics: Azacitidine; Cytidine; DNA (Cytosine-5-)-Methyltransferases; DNA Repair; DNA, Bacterial; Escherichia coli; Genes, Bacterial; Mutation; Phosphorylation; Rec A Recombinases; Recombination, Genetic; Uracil; Uridine | 1987 |
5-Azacytidine and 5-aza-2'-deoxycytidine behave as different antineoplastic agents in B16 melanoma.
Topics: Animals; Antineoplastic Agents; Azacitidine; Cell Survival; Cells, Cultured; Cytidine; Decitabine; Drug Resistance; Melanoma; Mice; Mutation; Uridine | 1987 |
Tetrahydrouridine, cytidine analogues, and hemoglobin F.
Topics: Agranulocytosis; Animals; Azacitidine; Cytidine Deaminase; Decitabine; Fetal Hemoglobin; Gene Expression Regulation; Globins; Granulocytes; Papio; Tetrahydrouridine; Uridine | 1985 |
Stimulatory effect of cycloheximide and related glutarimide antibiotics on liver uridine kinase.
Topics: Animals; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Azacitidine; Carbon Isotopes; Cell-Free System; Chromatography, Paper; Cycloheximide; Glutarates; Imides; Kinetics; Liver; Liver Regeneration; Male; Phosphotransferases; Rats; Stimulation, Chemical; Uridine | 1972 |
Latency of human measles virus in hamster cells.
Topics: Animals; Antigens, Viral; Azacitidine; Cell Fusion; Cell Line; Cells, Cultured; Cricetinae; Cycloheximide; Fibroblasts; Fluorescent Antibody Technique; Haplorhini; Kidney; Measles virus; Neutralization Tests; Parainfluenza Virus 1, Human; RNA, Viral; Tritium; Uridine; Viral Plaque Assay; Virus Replication | 1972 |
Dual effect of 5-azacytidine on the synthesis of liver ribonucleic acids. Lack of the relationship between metabolic transformation of orotic acid in vitro and its incorporation in vivo.
Topics: Animals; Azacitidine; Biotransformation; Carbon Isotopes; Carboxy-Lyases; Cell-Free System; Cytidine; In Vitro Techniques; Isotope Labeling; Liver; Orotic Acid; Pentosyltransferases; Phosphotransferases; Rats; RNA; RNA, Ribosomal; RNA, Transfer; Time Factors; Triazines; Uridine | 1972 |
Enhanced uridine kinase in rat liver following 5-azacytidine administration. In vivo characterization and properties of partially purified enzyme.
Topics: Adrenal Glands; Animals; Azacitidine; Cell-Free System; Cytidine; Dactinomycin; DNA; Dose-Response Relationship, Drug; Drug Stability; Injections, Intraperitoneal; Liver; Male; Nucleotidases; Phosphoric Monoester Hydrolases; Phosphotransferases; Protein Biosynthesis; Rats; RNA; Time Factors; Triazines; Uracil Nucleotides; Uridine | 1973 |
Metabolic alterations of liver regeneration. 8. Enhanced synthesis of DNA in the liver of 5-azacytidine-treated rats subjected to partial hepatectomy.
Topics: Animals; Autoradiography; Azacitidine; Carbon Isotopes; Cell Division; Cytidine; Depression, Chemical; DNA; Female; Hepatectomy; Liver; Liver Regeneration; Methods; Orotic Acid; Pyrimidine Nucleotides; Rats; RNA; Stimulation, Chemical; Thymine Nucleotides; Time Factors; Triazines; Tritium; Uridine | 1972 |
Uridine kinase in embryonic rat liver. Modulation of enzyme activity by 5-azacytidine.
Topics: Age Factors; Ammonium Sulfate; Animals; Azacitidine; Carbon Isotopes; Centrifugation; Chromatography; Female; Fetus; Gestational Age; Injections, Intraperitoneal; Liver; Phosphotransferases; Polysaccharides; Rats; Uridine | 1973 |
The mechanism of inhibition of protein synthesis by 5-azacytidine in HeLa cells.
Topics: Azacitidine; Carbon Radioisotopes; Centrifugation, Density Gradient; Cycloheximide; Dactinomycin; Half-Life; HeLa Cells; Kinetics; Leucine; Neoplasm Proteins; Peptide Chain Initiation, Translational; Polyribosomes; Protein Biosynthesis; RNA, Neoplasm; Tritium; Uridine | 1973 |
Enhancement of rat liver uridine kinase activity by various metabolic inhibitors.
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Azacitidine; Azauridine; Carbon Radioisotopes; Cell-Free System; Cycloheximide; Dactinomycin; Daunorubicin; Diet; Doxorubicin; In Vitro Techniques; Liver; Male; Orotic Acid; Phosphotransferases; Puromycin; Pyrimidines; Rats; Stimulation, Chemical; Thioacetamide; Thymus Gland; Uridine | 1974 |
Inhibition of ribosomal ribonucleic acid maturation by 5-azacytidine and 8-azaguanine in Novikoff hepatoma cells.
Topics: Animals; Azacitidine; Azaguanine; Carcinoma, Hepatocellular; Cells, Cultured; Cytidine; Dactinomycin; Electrophoresis, Polyacrylamide Gel; Fluorouracil; Guanosine; Isotope Labeling; Liver; Liver Neoplasms; Neoplasms, Experimental; Rats; RNA, Neoplasm; RNA, Ribosomal; Spectrophotometry, Ultraviolet; Time Factors; Tritium; Uridine | 1974 |
Kinetic studies on phosphorylation of 5-azacytidine with the purified uridine-cytidine kinase from calf thymus.
Topics: Animals; Azacitidine; Carbon Radioisotopes; Cattle; Chromatography, DEAE-Cellulose; Cytidine; Cytosine Nucleotides; Kinetics; Magnesium; Oxidative Phosphorylation; Phosphotransferases; Thymus Gland; Uracil Nucleotides; Uridine | 1974 |
Alteration of ribosomal precursor RNA in Novikoff hepatoma cells by 5-azacytidine. Studies on methylation of 45S and 32S RNA.
Topics: Animals; Azacitidine; Azaguanine; Carbon Radioisotopes; Carcinoma, Hepatocellular; Electrophoresis, Polyacrylamide Gel; Guanosine; Liver Neoplasms; Methionine; Neoplasms, Experimental; Rats; RNA, Neoplasm; RNA, Ribosomal; Transcription, Genetic; Tritium; Uridine | 1974 |
The effect of 5-azacytidine and dihydro-5-azacytidine on nuclear ribosomal RNA and poly(A) RNA synthesis in L1210 cells in vitro.
Topics: Adenosine; Animals; Azacitidine; Cells, Cultured; Depression, Chemical; Dose-Response Relationship, Drug; Leukemia L1210; Methionine; Methylation; Mice; Poly A; RNA; RNA, Heterogeneous Nuclear; RNA, Messenger; RNA, Ribosomal; Uridine | 1980 |
Effect of N-(phosphonacetyl)-L-aspartate on 5-azacytidine metabolism in P388 and L1210 cells.
Topics: Animals; Aspartate Carbamoyltransferase; Aspartic Acid; Azacitidine; Cell Division; Cytidine; DNA, Neoplasm; Leukemia L1210; Leukemia, Experimental; Mice; Neoplasm Proteins; Organophosphorus Compounds; Phosphonoacetic Acid; RNA, Neoplasm; Uridine | 1981 |
Altered 5-azacytidine metabolism following 3-deazauridine treatment of L5178Y and human myeloblasts.
Topics: 3-Deazauridine; Animals; Azacitidine; Biological Transport; Clone Cells; DNA, Neoplasm; Humans; Leukemia L5178; Leukemia, Experimental; Leukemia, Myeloid, Acute; Mice; Neoplasm Proteins; Ribonucleotides; RNA, Neoplasm; Uridine | 1980 |
Effect of 3-deazauridine on the metabolism, toxicity, and antitumor activity of azacitidine in mice bearing L1210 leukemia sensitive and resistant to cytarabine.
Topics: 3-Deazauridine; Animals; Azacitidine; Chromatography, High Pressure Liquid; Cytarabine; Drug Therapy, Combination; Lethal Dose 50; Leukemia L1210; Mice; Mice, Inbred DBA; Purine Nucleotides; Pyrimidine Nucleotides; Uridine | 1983 |
Effect of uridine on response of 5-azacytidine-resistant human leukemic cells to inhibitors of de novo pyrimidine synthesis.
Topics: Azacitidine; Cell Line; Drug Resistance; Humans; Kinetics; Leukemia, Myeloid, Acute; Pyrimidine Nucleotides; Pyrimidines; Structure-Activity Relationship; Uridine | 1984 |
The Escherichia coli protein YjjG is a house-cleaning nucleotidase in vivo.
Topics: Azacitidine; Bromodeoxyuridine; Decitabine; Deoxyuridine; DNA Damage; Escherichia coli; Escherichia coli Proteins; Fluorouracil; Models, Biological; Molecular Structure; Mutation; N-Glycosyl Hydrolases; Nucleotidases; Orotic Acid; Substrate Specificity; Thymidine Monophosphate; Uridine | 2007 |
Epigenetic reversal of acquired resistance to 5-fluorouracil treatment.
Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Base Sequence; Cell Line, Tumor; Colorectal Neoplasms; CpG Islands; Decitabine; DNA Methylation; Drug Resistance, Neoplasm; Epigenomics; Fluorouracil; Gene Expression Regulation, Neoplastic; Gene Order; Humans; Mice; Mice, Nude; Molecular Sequence Data; Nucleoside-Phosphate Kinase; Promoter Regions, Genetic; RNA Stability; Uridine; Xenograft Model Antitumor Assays | 2009 |
Cellular Uptake of Decitabine by Equilibrative Nucleoside Transporters in HCT116 Cells.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Carrier Proteins; Colorectal Neoplasms; Decitabine; DNA Methylation; Equilibrative Nucleoside Transporter 1; Gene Expression; HCT116 Cells; Humans; Melanoma-Specific Antigens; Real-Time Polymerase Chain Reaction; RNA, Messenger; Thioinosine; Uridine | 2015 |
Oral Azacitidine and Cedazuridine Approximate Parenteral Azacitidine Efficacy in Murine Model.
Topics: Administration, Oral; Animals; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Disease Models, Animal; Female; Haplorhini; Humans; Infusions, Parenteral; Mice; Treatment Outcome; Uridine | 2020 |
The path to approval for oral hypomethylating agents in acute myeloid leukemia and myelodysplastic syndromes.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Biological Availability; Clinical Trials, Phase III as Topic; Decitabine; DNA Methylation; Drug Approval; Drug Combinations; Humans; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Randomized Controlled Trials as Topic; Remission Induction; Uridine | 2021 |
Oral hypomethylating agents: beyond convenience in MDS.
Topics: Administration, Oral; Aged; Antimetabolites, Antineoplastic; Azacitidine; Decitabine; Female; Humans; Myelodysplastic Syndromes; Quality of Life; Uridine | 2021 |