azacitidine has been researched along with tretinoin in 92 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (9.78) | 18.7374 |
| 1990's | 9 (9.78) | 18.2507 |
| 2000's | 34 (36.96) | 29.6817 |
| 2010's | 34 (36.96) | 24.3611 |
| 2020's | 6 (6.52) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Parker, RF; Scott, RE; Wang, H; Witte, MM | 1 |
| Hirano, T; Kaisho, T; Nakajima, K; Oritani, K | 1 |
| Miller, K; Pak, CH; Poduslo, SE | 1 |
| Doré, BT; Momparler, LF; Momparler, RL | 1 |
| Hassan, HT; Maurer, HR; Veit, A | 1 |
| Hall, RE; Leftwich, JA | 1 |
| Boeije, LC; de Waal, F; Levva, A; Pinedo, HM; Schwartsmann, G | 1 |
| Leyva, A; Pinedo, HM; Schwartsmann, G | 1 |
| Allalouf, D; Friedman, J; Levinsky, H; Seger, M | 1 |
| Pierce, GB; Speers, WC | 1 |
| Behnke, O; Olsson, L; Sørensen, HR | 1 |
| Heidelberger, C; Mondal, S | 1 |
| Ishida, H; Niwa, O; Sugahara, T; Yokota, Y | 1 |
| Grisham, JW; Nelson, KG; Tsao, MS | 1 |
| Lee, CH; Wei, LN | 1 |
| Bulic-Jakus, F; Crnek, V; Skreb, N; Stepic, J; Vlahovic, M | 1 |
| Côté, S; Momparler, RL | 1 |
| Rutledge, JC | 1 |
| Ferguson, AT; Orlandi, R; Sacchi, N; Sirchia, SM; Sironi, E; Subramanyan, S; Sukumar, S | 1 |
| Arapshian, A; Kuppumbatti, YS; Mira-y-Lopez, R | 1 |
| Hayashi, Y; Honma, Y; Niitsu, N; Sugita, K | 1 |
| Angliker, H; Benjamin, D; Jost, JP; Siegmann, M; Thiry, S; Zheng, Y; Zhu, B | 1 |
| Marx, J | 1 |
| Corsaro, M; Di Croce, L; Fanelli, M; Faretta, M; Fazi, F; Fuks, F; Kouzarides, T; Lo Coco, F; Minucci, S; Nervi, C; Pelicci, PG; Raker, VA | 1 |
| Hofmann, WK; Koeffler, HP | 1 |
| Carpenter, MK; Police, S; Rao, N; Xu, C | 1 |
| Maatouk, DM; Resnick, JL | 1 |
| Andrews, LG; Hansen, NJ; Key, JS; Lopatina, NG; Pita, MA; Poole, JC; Saldanha, SN; Tollefsbol, TO | 1 |
| Chen, XQ; Garcia-Manero, G; Higuchi, E; Issa, JP; Kondo, Y; Lotan, R; Youssef, EM | 1 |
| Allemanni, G; Banelli, B; Brignole, C; Casciano, I; Croce, M; De Ambrosis, A; di Vinci, A; Ferrini, S; Gelvi, I; Pagnan, G; Ponzoni, M; Romani, M | 1 |
| Gudas, LJ; Mongan, NP | 1 |
| Andollo, N; Andrade, R; Aréchaga, J; Arlucea, J; Asumendi, A; Boyano, MD; Eguizabal, C; Zalduendo, MM | 1 |
| Choi, EJ; Kim, JS; Kim, YH; Seo, JH; Whang, YM; Yoo, YD | 1 |
| Doenecke, D; Happel, N; Schulze, E | 1 |
| Brooks, JD; Kaygusuz, G; Kim, H; Lapointe, J; Li, C; Ong, DE; Pollack, JR; van de Rijn, M | 1 |
| Cao, F; Gambhir, SS; Gonzalgo, ML; Krishnan, M; Park, JM; Paulmurugan, R; Tseng, JR; Wang, D; Wu, JC | 1 |
| Lippman, SM; Sabichi, AL; Xu, X | 1 |
| Biddle, A; Bounds, R; Dmitrovsky, E; Dragnev, KH; Freemantle, SJ; Li, N; Ma, Y; Nitkin, C; Petty, WJ | 1 |
| Chan, WW; Chim, CS; Kwong, YL; Pang, A | 1 |
| Andreeff, M; Contractor, R; Issa, JP; Jin, L; Kondo, Y; Konopleva, M; Miyake, K; Miyake, N; Nagaoka, I; Ohsaka, A; Ruvolo, V; Tabe, Y; Tsutsumi-Ishii, Y | 1 |
| Kalberer, CP; Langenkamp, U; Rohner, A; Siegler, U; Wodnar-Filipowicz, A | 1 |
| Cohn, SL; Cornell, J; McArdle, L; Nair, PN; Stallings, RL | 1 |
| Cortes, J; Estey, EH; Estrov, Z; Faderl, S; Garcia-Manero, G; Giles, F; Issa, JP; Kantarjian, HM; Ouzounian, S; Pierce, S; Quezada, A; Ravandi, F; Soriano, AO; Wierda, WG; Yang, H | 1 |
| Aydin, D; Doğan, AL; Güç, D; Taşbasan, B; Tazebay, UH; Tuncel, M; Uğur, O; Yaman, E | 2 |
| Ai, GW; Liu, W; Ma, XX; Meng, XQ; Meng, YS; Wei, R; Zhang, YX | 1 |
| Karp, J | 1 |
| Jin, LH; Lei, L; Li, QM; Shan, ZY; Su, DJ; Wang, N; Zhang, XM | 1 |
| Araúzo-Bravo, MJ; Do, JT; Han, DW; Jaenisch, R; Lee, HT; Lee, SH; Meissner, A; Schöler, HR | 1 |
| Agate, L; Capodanno, A; Ciampi, R; Collecchi, P; Elisei, R; Miasaki, FY; Pinchera, A; Vivaldi, A | 1 |
| Aki, N; Emoto, N; Kage, H; Kusakabe, M; Nagase, T; Nakajima, J; Ohishi, N; Takai, D; Watanabe, K; Yatomi, Y | 1 |
| Albert, M; Gudas, LJ; Scognamiglio, T; Tang, XH | 1 |
| Lee, HW; Liu, W; Liu, Y; Rodgers, GP; Wang, R | 1 |
| Calin, GA; Fang, Z; Garcia-Manero, G; Hu, Y; Kantarjian, HM; Wei, Y; Yang, H | 1 |
| Boëlle, PY; Chevret, S; Chomienne, C; Cras, A; Daniel, MT; de Labarthe, A; Degos, L; Dombret, H; Fenaux, P; Gardin, C; Maarek, O; Malfuson, JV; Marolleau, JP; Maury, S; Raffoux, E; Recher, C; Reman, O; Rousselot, P; Turlure, P; Victor, M | 1 |
| Cheong, SC; Gan, CP; Hamid, S; Hor, SY; Ismail, SM; Saunders, N; Teo, SH; Wan Mustafa, WM; Zain, RB | 1 |
| Biermann, K; Gillis, A; Looijenga, LH; Nettersheim, D; Schorle, H | 1 |
| Chen, NN; Chen, XY; Fu, YS; Kong, QY; Li, H; Li, Y; Liu, J; Liu, ZL; Wu, ML | 1 |
| Chen, NN; Chen, XY; Fu, YS; Kong, QY; Li, H; Liu, J; Ma, JX; Shu, XH; Sun, Y; Wang, Q; Wu, ML; Yang, XH; Zhang, KL | 1 |
| Chen, JJ; Chen, Y; Lin, DJ; Long, ZJ; Wu, X; Xiao, RZ; Xiong, MJ | 1 |
| Kalinina, N; Lopatina, T; Parfyonova, Y; Pavlova, G; Revishchin, A; Rybalkina, E; Tkachuk, V | 1 |
| Fujiki, A; Hirashima, Y; Hosoi, H; Imamura, T; Kawashima, S; Miyachi, M; Nakatani, T; Sakamoto, K; Sugita, K; Yagyu, S; Yoshida, H | 1 |
| Baraty, C; Bianco, C; Castro, NP; Gonzales, M; Held, N; Karasawa, H; Rangel, MC; Rollman, K; Salomon, DS; Strizzi, L | 1 |
| Kewitz, S; Staege, MS | 1 |
| Kurokawa, M; Nannya, Y | 1 |
| Glasow, A; Kortmann, RD; Patties, I | 1 |
| Bannert, S; Bender, S; Benner, A; Dreidax, D; Duffy, D; Ehemann, V; Fischer, M; Henrich, KO; Lindner, S; Oakes, CC; Pfister, S; Saadati, M; Schröder, C; Schulte, JH; Schwarzl, T; Westermann, F | 1 |
| Brodská, B; Holoubek, A; Otevřelová, P | 1 |
| Haferlach, T; Herr, W; Klobuch, S; Rehli, M; Reichle, A; Schelker, R; Thomas, S; Troppmann, M; Zaiss, S | 1 |
| Cen, J; Chen, Z; Gu, W; Hu, S; Qiu, G; Wang, R; Wei, J; Xiang, L; Xie, X | 1 |
| Anisimov, SV; Domnina, AP; Fridlianskaia, II; Grinchuk, TM; Kovaleva, ZV; Kozhukharova, IV; Nikol'skiĭ, NN; Pugovkina, NA; Puzanov, MV; Zemel'ko, VI | 1 |
| Cieslik, C; Döhner, K; Grishina, O; Hackanson, B; Lübbert, M; Lubrich, B; May, AM; Müller, MJ; Schmoor, C | 1 |
| Chang, J; Deng, F; Feng, P; Feng, R; Fu, H; He, L; Hu, Y; Huang, W; Lei, H; Wang, X | 1 |
| Ackermann, S; Berthold, F; Dreidax, D; Engesser, A; Fischer, M; Henrich, KO; Hero, B; Hertwig, F; Ikram, F; Kahlert, Y; Kocak, H; Nürnberg, P; Roels, F; Volland, R; Westermann, F | 1 |
| Beckhove, P; Gal, Z; Grabe, N; Herold-Mende, C; Lahrmann, B; Lasitschka, F; Mock, A; Mossemann, J; Schmezer, P; Schmoch, T; Unterberg, A | 1 |
| Dong, W; Gu, W; Hua, X; Li, H; Lin, Y; Ling, Y; Wu, W; Xiang, L; Xie, X; Yan, F | 1 |
| Glasow, A; Kortmann, RD; Menzel, F; Patties, I | 1 |
| Condom, E; Esteller, M; Gomez, A; Moran, S; Romero, OA; Sanchez-Cespedes, M; Torres-Diz, M; Verdura, S; Villanueva, A | 1 |
| Balleari, E; Bernal, T; Beyne-Rauzy, O; Bordessoule, D; Calabuig, M; Cametti, G; Campelo, MD; Cheze, S; Cony-Makhoul, P; Dreyfus, F; Fenaux, P; Fensterl, J; Ferrero, D; Gaidano, G; Germing, U; Gioia, D; Götze, K; Guerci-Bresler, A; Hamel, JF; Kaivers, J; Kelaidi, C; Komrokji, R; Kotsianidis, I; Müller-Thomas, C; Pane, F; Park, S; Ramos, F; Roboz, GJ; Rose, C; Sanna, A; Santini, V; Sanz, GF; Sapena, R; Sekeres, MA; Stamatoullas, A; Steensma, DP; Thépot, S; Toma, A; Vey, N; Wattel, E | 1 |
| Fell, SM; Holmberg, J; Kogner, P; Li, S; Nyman, U; Schlisio, S; Shi, Y; Södersten, E; Surova, O; Toskas, K; Westerlund, I | 1 |
| Cao, Y; Cen, JN; Dong, WM; Gu, WY; Lin, Y; Liu, Y; Xiang, LL; Xie, XB | 1 |
| Naoe, T | 1 |
| da Costa Rosa, M; Riggins, GJ; Yamashita, AS | 1 |
| Herold, T; Hiddemann, W; Rausch, C; Spiekermann, K; von Bergwelt-Baildon, M | 1 |
| Han, Y; Jiang, L; Jin, J; Lang, W; Li, K; Lin, P; Liu, X; Lu, C; Luo, Y; Ma, L; Mei, C; Ren, Y; Shen, C; Sun, J; Tong, H; Wang, L; Wang, Y; Xu, G; Yang, H; Yang, W; Ye, L; Ye, X; Zhang, H; Zhang, Q; Zhang, X; Zhou, X; Zhu, S | 1 |
| Al-Ali, HK; Becker, H; Brugger, W; Bug, G; Crysandt, M; De Wit, M; Döhner, H; Döhner, K; Duyster, J; Ganser, A; Giagounidis, A; Götze, KS; Grishina, O; Hackanson, B; Heil, G; Heuser, M; Krauter, J; Kündgen, A; Lübbert, M; May, AM; Müller-Tidow, C; Neubauer, A; Rummelt, C; Salih, HR; Schlenk, RF; Schmoor, C; Scholl, S; Wäsch, R | 1 |
| Ali, KA; Anderson, E; Anderson, W; Dhar, A; Gu, CJ; Hübner, J; Kita, R; Lacher, MD; Loh, ML; Richardson, M; Santaguida, MT; Stieglitz, E; Strachan, DC; Tasian, SK; Yam, G | 1 |
4 review(s) available for azacitidine and tretinoin
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Tumors as caricatures of the process of tissue renewal: prospects for therapy by directing differentiation.
Topics: Azacitidine; Cell Differentiation; Colony-Stimulating Factors; Embryonic Induction; Humans; Neoplasms; Peptides; Transforming Growth Factors; Tretinoin | 1988 |
Developmental toxicity induced during early stages of mammalian embryogenesis.
Topics: Abnormalities, Drug-Induced; Animals; Azacitidine; Blastocyst; Embryonic and Fetal Development; Gene Expression Regulation, Developmental; Mammals; Mice; Mutagens; Teratogens; Tretinoin; Xenobiotics; Zygote | 1997 |
＜Editors' Choice＞ How to improve outcomes of elderly patients with acute myeloid leukemia: era of excitement.
Topics: Aged; Aged, 80 and over; Aminopyridines; Aniline Compounds; Antineoplastic Agents; Arsenic Trioxide; Azacitidine; Benzimidazoles; Bridged Bicyclo Compounds, Heterocyclic; Decitabine; fms-Like Tyrosine Kinase 3; Humans; Isocitrate Dehydrogenase; Leukemia, Myeloid, Acute; Molecular Targeted Therapy; Phenylurea Compounds; Precision Medicine; Proto-Oncogene Proteins c-bcl-2; Pyrazines; Smoothened Receptor; Staurosporine; Sulfonamides; Survival Rate; Tretinoin; Triazines | 2020 |
5 trial(s) available for azacitidine and tretinoin
| Article | Year |
|---|---|
Safety and clinical activity of the combination of 5-azacytidine, valproic acid, and all-trans retinoic acid in acute myeloid leukemia and myelodysplastic syndrome.
Topics: Acetylation; Adolescent; Adult; Aged; Aged, 80 and over; Azacitidine; Child; Child, Preschool; DNA Methylation; Dose-Response Relationship, Drug; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Gene Expression Regulation; Histones; Humans; Leukemia, Myeloid, Acute; Middle Aged; Myelodysplastic Syndromes; RNA, Messenger; Tretinoin; Valproic Acid | 2007 |
Levels of miR-29b do not predict for response in patients with acute myelogenous leukemia treated with the combination of 5-azacytidine, valproic acid, and ATRA.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cohort Studies; Gene Expression Regulation, Neoplastic; Humans; Leukemia, Myeloid, Acute; Leukocytes, Mononuclear; MicroRNAs; Myelodysplastic Syndromes; Treatment Outcome; Tretinoin; Valproic Acid | 2011 |
Phase 2 clinical trial of 5-azacitidine, valproic acid, and all-trans retinoic acid in patients with high-risk acute myeloid leukemia or myelodysplastic syndrome.
Topics: Aged; Aged, 80 and over; Anticonvulsants; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; DNA Methylation; DNA, Neoplasm; Epigenomics; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Polymerase Chain Reaction; Survival Rate; Treatment Outcome; Tretinoin; Valproic Acid | 2010 |
DECIDER: prospective randomized multicenter phase II trial of low-dose decitabine (DAC) administered alone or in combination with the histone deacetylase inhibitor valproic acid (VPA) and all-trans retinoic acid (ATRA) in patients >60 years with acute mye
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Clinical Protocols; Decitabine; Female; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Tretinoin; Valproic Acid | 2015 |
Activity of decitabine combined with all-
Topics: Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Decitabine; Humans; Leukemia, Myeloid, Acute; Tretinoin | 2023 |
83 other study(ies) available for azacitidine and tretinoin
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Repression of SV40 T oncoprotein expression by DMSO.
Topics: Acetamides; Animals; Antigens, Polyomavirus Transforming; Azacitidine; Blotting, Northern; Blotting, Western; Butyrates; Butyric Acid; Cell Line, Transformed; Cell Transformation, Neoplastic; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Insulin; Interferons; Mice; Phenotype; Stem Cells; T-Lymphocytes; Tretinoin | 1992 |
Retinoic acid inhibits interleukin-6-induced macrophage differentiation and apoptosis in a murine hematopoietic cell line, Y6.
Topics: Animals; Apoptosis; Azacitidine; Blotting, Northern; Cell Differentiation; Cell Division; Cell Line; Cycloheximide; Dimethyl Sulfoxide; DNA; Gene Expression; Genes, jun; Genes, myc; Hematopoietic Stem Cells; Interleukin-6; Kinetics; Macrophages; Mice; Mice, Inbred BALB C; RNA; Tetradecanoylphorbol Acetate; Tretinoin | 1992 |
Induction of cerebroside synthesis in oligodendroglia.
Topics: Animals; Animals, Newborn; Azacitidine; Brain; Cattle; Cells, Cultured; Cerebrosides; Hydrocortisone; Ketone Bodies; Myelin Sheath; Oligodendroglia; Phorbol Esters; Rats; Tretinoin; Triiodothyronine | 1990 |
Effect of 5-aza-2'-deoxycytidine and retinoic acid on differentiation and c-myc expression in HL-60 myeloid leukemic cells.
Topics: Antineoplastic Agents; Azacitidine; Cell Differentiation; Cell Division; Decitabine; Drug Synergism; Gene Expression; Humans; Proto-Oncogene Proteins c-myc; Tretinoin; Tumor Cells, Cultured | 1990 |
Synergistic interactions between differentiation-inducing agents in inhibiting the proliferation of HL-60 human myeloid leukaemia cells in clonogenic micro assays.
Topics: Acetamides; Aged; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cell Differentiation; Cell Division; Drug Synergism; Humans; Leukemia, Myeloid, Acute; Tretinoin; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1991 |
Enhancement of phorbol diester-induced HL-60-mediated cytotoxicity by retinoic acid, dimethyl sulfoxide, and 5-azacytidine.
Topics: Azacitidine; Cell Differentiation; Cell Line; Cytotoxicity, Immunologic; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Leukemia, Myeloid, Acute; Macrophages; Monocytes; Phorbol 12,13-Dibutyrate; Phorbol Esters; Tetradecanoylphorbol Acetate; Tretinoin | 1986 |
Growth inhibitory effects of 5-aza-2'-deoxycytidine in HL-60 promyelocytic leukemia cells resistant to differentiation induction.
Topics: Azacitidine; Cell Cycle; Cell Differentiation; Cell Division; Cell Line; Decitabine; Dimethyl Sulfoxide; Humans; Nitroblue Tetrazolium; Tretinoin | 1986 |
Resistance of HL-60 promyelocytic leukemia cells to induction of differentiation and its reversal by combination treatment.
Topics: Antineoplastic Agents; Azacitidine; Cell Differentiation; Cell Line; Decitabine; Dimethyl Sulfoxide; Drug Synergism; Humans; Leukemia, Myeloid, Acute; Tretinoin | 1987 |
Modulation of carcinoembryonic antigen release by HT-29 colon carcinoma line in the presence of different agents.
Topics: Acetamides; Azacitidine; Butyrates; Butyric Acid; Carcinoembryonic Antigen; Cell Differentiation; Colonic Neoplasms; Drug Synergism; Formamides; Humans; Tetradecanoylphorbol Acetate; Tretinoin | 1987 |
Modulatory effects of 5-azacytidine, phorbol ester, and retinoic acid on the malignant phenotype of human lung cancer cells.
Topics: Animals; Azacitidine; Carcinoma, Small Cell; Cell Line; Clone Cells; Humans; Lung Neoplasms; Mice; Mice, Nude; Mitosis; Neoplasm Transplantation; Phenotype; Phorbols; Tetradecanoylphorbol Acetate; Tretinoin | 1985 |
Inhibition of induced differentiation of C3H/10T 1/2 clone 8 mouse embryo cells by tumor promoters.
Topics: Animals; Antipain; Azacitidine; Cell Differentiation; Clone Cells; Embryo, Mammalian; Epidermal Growth Factor; Mice; Muscles; Phorbol Esters; Phorbols; Tetradecanoylphorbol Acetate; Tretinoin | 1980 |
Independent mechanisms involved in suppression of the Moloney leukemia virus genome during differentiation of murine teratocarcinoma cells.
Topics: Animals; Azacitidine; Bromodeoxyuridine; Cell Cycle; Cell Differentiation; Cell Line; DNA, Viral; Gene Expression Regulation; Genes, Viral; Methylation; Mice; Moloney murine leukemia virus; Recombination, Genetic; Teratoma; Transcription, Genetic; Transfection; Tretinoin | 1983 |
Biochemical effects of 12-O-tetradecanoylphorbol-13-acetate, retinoic acid, phenobarbital, and 5-azacytidine on a normal rat liver epithelial cell line.
Topics: Animals; Azacitidine; Cell Division; Cells, Cultured; Fibronectins; Liver; Phenobarbital; Phorbols; Rats; Tetradecanoylphorbol Acetate; Tretinoin | 1984 |
Demethylation in the 5'-flanking region of mouse cellular retinoic acid binding protein-I gene is associated with its high level of expression in mouse embryos and facilitates its induction by retinoic acid in P19 embryonal carcinoma cells.
Topics: Animals; Azacitidine; Base Sequence; Carcinoma, Embryonal; Deoxyribonuclease HpaII; Deoxyribonucleases, Type II Site-Specific; DNA; Embryonic and Fetal Development; Gene Expression Regulation, Developmental; Methylation; Mice; Molecular Sequence Data; Promoter Regions, Genetic; Receptors, Retinoic Acid; Restriction Mapping; RNA, Messenger; Transcription, Genetic; Tretinoin; Tumor Cells, Cultured; Up-Regulation | 1994 |
Differentiation and growth of rat egg-cylinders cultured in vitro in a serum-free and protein-free medium.
Topics: Animals; Azacitidine; Cell Differentiation; Culture Media; Culture Media, Serum-Free; Embryo, Mammalian; Female; In Vitro Techniques; Proteins; Rats; Rats, Inbred F344; Serum Albumin, Bovine; Transferrin; Tretinoin | 1993 |
Activation of the retinoic acid receptor beta gene by 5-aza-2'-deoxycytidine in human DLD-1 colon carcinoma cells.
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Antineoplastic Agents; Azacitidine; Blotting, Northern; Blotting, Southern; Cell Line; Colonic Neoplasms; Decitabine; DNA Methylation; Exons; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Receptors, Retinoic Acid; Tretinoin; Tumor Stem Cell Assay | 1997 |
Evidence of epigenetic changes affecting the chromatin state of the retinoic acid receptor beta2 promoter in breast cancer cells.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Breast; Breast Neoplasms; Cell Line; Chromatin; CpG Islands; Decitabine; DNA Methylation; Enzyme Inhibitors; Epithelial Cells; Female; Gene Expression Regulation; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Promoter Regions, Genetic; Receptors, Estrogen; Receptors, Retinoic Acid; Tretinoin; Tumor Cells, Cultured | 2000 |
Methylation of conserved CpG sites neighboring the beta retinoic acid response element may mediate retinoic acid receptor beta gene silencing in MCF-7 breast cancer cells.
Topics: Adenocarcinoma; Azacitidine; Base Sequence; Breast Neoplasms; Clone Cells; CpG Islands; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Reporter; Humans; Molecular Sequence Data; Neoplasm Proteins; Promoter Regions, Genetic; Receptors, Retinoic Acid; Sequence Analysis, DNA; Transcriptional Activation; Transfection; Tretinoin; Tumor Cells, Cultured | 2000 |
Sensitization by 5-aza-2'-deoxycytidine of leukaemia cells with MLL abnormalities to induction of differentiation by all-trans retinoic acid and 1alpha,25-dihydroxyvitamin D3.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Calcitriol; Cell Differentiation; Chromosome Breakage; Chromosomes, Human, Pair 11; Decitabine; DNA Methylation; DNA-Binding Proteins; Histone-Lysine N-Methyltransferase; Humans; Leukemia; Myeloid-Lymphoid Leukemia Protein; Proto-Oncogenes; Transcription Factors; Tretinoin; Tumor Cells, Cultured | 2001 |
Overexpression of 5-methylcytosine DNA glycosylase in human embryonic kidney cells EcR293 demethylates the promoter of a hormone-regulated reporter gene.
Topics: Azacitidine; Blotting, Southern; Cell Line; DNA Glycosylases; DNA Methylation; Ecdysterone; Enhancer Elements, Genetic; Gene Amplification; Gene Dosage; Gene Expression Regulation; Gene Silencing; Genes, Reporter; Hormones; Humans; Kidney; Macromolecular Substances; Mutation; N-Glycosyl Hydrolases; Precipitin Tests; Promoter Regions, Genetic; Receptors, Retinoic Acid; Response Elements; Retinoid X Receptors; Transcription Factors; Transfection; Transgenes; Tretinoin | 2001 |
Cancer research. Leukemia protein spurs gene silencing.
Topics: Azacitidine; Cell Division; Cell Transformation, Neoplastic; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Gene Silencing; Genes, Tumor Suppressor; Humans; Leukemia, Promyelocytic, Acute; Leukocytes; Mutation; Neoplasm Proteins; Oncogene Proteins, Fusion; Promoter Regions, Genetic; Receptors, Retinoic Acid; Tretinoin; Zinc | 2002 |
Methyltransferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor.
Topics: Azacitidine; Binding Sites; Cell Differentiation; Cell Line; Cell Nucleus; Cell Transformation, Neoplastic; Cloning, Molecular; CpG Islands; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; Exons; Gene Expression; Gene Silencing; Histone Deacetylases; Humans; Leukemia, Promyelocytic, Acute; Mutation; Neoplasm Proteins; Oncogene Proteins, Fusion; Promoter Regions, Genetic; Receptors, Retinoic Acid; Recombinant Fusion Proteins; Transcription Factors; Tretinoin; Tumor Cells, Cultured; Zinc | 2002 |
Differentiation therapy for myelodysplastic syndrome.
Topics: Azacitidine; Cell Differentiation; Decitabine; DNA Modification Methylases; Enzyme Inhibitors; Histone Deacetylase Inhibitors; HL-60 Cells; Humans; Myelodysplastic Syndromes; Tretinoin | 2002 |
Characterization and enrichment of cardiomyocytes derived from human embryonic stem cells.
Topics: 1-Methyl-3-isobutylxanthine; Azacitidine; Cell Differentiation; Cell Size; Decitabine; Diltiazem; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Embryo, Mammalian; Gene Expression Regulation; Humans; Immunohistochemistry; Isoproterenol; Ki-67 Antigen; Myocardium; Myosin Heavy Chains; Phenylephrine; Stem Cells; Time Factors; Tretinoin; Troponin I | 2002 |
Continuing primordial germ cell differentiation in the mouse embryo is a cell-intrinsic program sensitive to DNA methylation.
Topics: Alkaline Phosphatase; Animals; Antigens, Nuclear; Azacitidine; Biomarkers; Cell Differentiation; Cell Division; Cells, Cultured; DNA Methylation; Female; Germ Cells; Hydroxamic Acids; Male; Meiosis; Mice; Mice, Inbred Strains; Nuclear Proteins; Oogonia; Sex Differentiation; Spermatogonia; Tetradecanoylphorbol Acetate; Tretinoin | 2003 |
Control mechanisms in the regulation of telomerase reverse transcriptase expression in differentiating human teratocarcinoma cells.
Topics: Antineoplastic Agents; Azacitidine; Catalytic Domain; Cell Differentiation; DNA (Cytosine-5-)-Methyltransferases; DNA-Binding Proteins; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Humans; Hydroxamic Acids; Methylation; Promoter Regions, Genetic; Telomerase; Teratocarcinoma; Tretinoin; Tumor Cells, Cultured | 2003 |
Hypermethylation and silencing of the putative tumor suppressor Tazarotene-induced gene 1 in human cancers.
Topics: Antineoplastic Agents; Azacitidine; Cell Division; Cell Line, Tumor; Decitabine; DNA Methylation; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Tumor Suppressor; Humans; Membrane Proteins; Neoplasms; Promoter Regions, Genetic; Protein Biosynthesis; Proteins; Receptors, Retinoic Acid; Tretinoin | 2004 |
Caspase-8 gene expression in neuroblastoma.
Topics: Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Caspase 8; Caspases; Cell Line, Tumor; CpG Islands; DNA; DNA Methylation; Gene Expression Regulation, Neoplastic; Humans; Interferon-gamma; Neuroblastoma; Promoter Regions, Genetic; RNA; Tretinoin | 2004 |
Valproic acid, in combination with all-trans retinoic acid and 5-aza-2'-deoxycytidine, restores expression of silenced RARbeta2 in breast cancer cells.
Topics: Azacitidine; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Chromatin Immunoprecipitation; Decitabine; DNA Primers; Enzyme Inhibitors; Histone Deacetylases; Histones; Humans; Receptors, Retinoic Acid; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Messenger; Time Factors; Tretinoin; Valproic Acid | 2005 |
Structural and functional preservation of specific sequences of DNA and mRNA in apoptotic bodies from ES cells.
Topics: Animals; Apoptosis; Azacitidine; Biotinylation; Blotting, Northern; Blotting, Southern; Blotting, Western; Cell Differentiation; Cell Proliferation; Chromatin; Decitabine; Deoxyribonuclease I; DNA; DNA Methylation; Dose-Response Relationship, Drug; Embryo, Mammalian; Flow Cytometry; Mice; Microscopy, Electron; Models, Genetic; Propidium; Protein Biosynthesis; Protein Conformation; RNA, Messenger; Stem Cells; Time Factors; Tretinoin | 2005 |
Hyperacetylation enhances the growth-inhibitory effect of all-trans retinoic acid by the restoration of retinoic acid receptor beta expression in head and neck squamous carcinoma (HNSCC) cells.
Topics: Acetylation; Antineoplastic Agents; Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tumor; Decitabine; DNA Methylation; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Lysine; Promoter Regions, Genetic; Receptors, Retinoic Acid; Tretinoin | 2005 |
Characterisation of human histone H1x.
Topics: Amino Acid Sequence; Animals; Azacitidine; Butyrates; Cell Line; DNA; Gene Expression Regulation; HeLa Cells; Histones; HL-60 Cells; Humans; Molecular Sequence Data; Nucleosomes; Perchlorates; Sequence Alignment; Tretinoin; U937 Cells | 2005 |
The retinoic acid synthesis gene ALDH1a2 is a candidate tumor suppressor in prostate cancer.
Topics: Aldehyde Dehydrogenase; Aldehyde Dehydrogenase 1 Family; Azacitidine; Base Sequence; Cell Line, Tumor; Decitabine; DNA Methylation; Enzyme Inhibitors; Gene Expression Profiling; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Isoenzymes; Male; Molecular Sequence Data; Neoplastic Stem Cells; Promoter Regions, Genetic; Prostate; Prostatic Neoplasms; Retinal Dehydrogenase; Tretinoin | 2005 |
Effects of epigenetic modulation on reporter gene expression: implications for stem cell imaging.
Topics: Animals; Azacitidine; Cell Line; Cell Proliferation; Cell Survival; DNA Methylation; DNA Modification Methylases; Epigenesis, Genetic; Gene Silencing; Genes, Reporter; Hydroxamic Acids; Luciferases, Firefly; Muscle, Skeletal; Myoblasts, Cardiac; Rats; Rats, Sprague-Dawley; Stem Cell Transplantation; Stem Cells; Tretinoin | 2006 |
RARbeta1': primed to fight retinoid resistance in lung carcinogenesis.
Topics: Alternative Splicing; Antimetabolites, Antineoplastic; Azacitidine; Cell Line, Tumor; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Protein Isoforms; Receptors, Retinoic Acid; Respiratory Mucosa; Retinoid X Receptors; Tretinoin | 2005 |
A novel retinoic acid receptor beta isoform and retinoid resistance in lung carcinogenesis.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Bone Morphogenetic Proteins; Bronchial Neoplasms; Cell Line, Tumor; DNA Methylation; Gene Expression Regulation, Neoplastic; Growth Differentiation Factor 15; GTP-Binding Proteins; Humans; Immunoblotting; Luciferases; Lung Neoplasms; Membrane Proteins; Promoter Regions, Genetic; Protein Glutamine gamma Glutamyltransferase 2; Protein Isoforms; Proto-Oncogene Proteins c-fos; Receptors, Retinoic Acid; Respiratory Mucosa; Reverse Transcriptase Polymerase Chain Reaction; Transcription, Genetic; Transfection; Transglutaminases; Tretinoin | 2005 |
Preferential methylation of Wnt inhibitory factor-1 in acute promyelocytic leukemia: an independent poor prognostic factor.
Topics: Adaptor Proteins, Signal Transducing; Azacitidine; Biomarkers, Tumor; Carrier Proteins; Cell Line, Tumor; Cell Proliferation; Humans; Leukemia, Promyelocytic, Acute; Methylation; Multivariate Analysis; Prognosis; Recurrence; Remission Induction; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; Risk Factors; RNA, Messenger; Sensitivity and Specificity; Survival Rate; Tretinoin; Tumor Cells, Cultured | 2006 |
PML-RARalpha and AML1-ETO translocations are rarely associated with methylation of the RARbeta2 promoter.
Topics: Antineoplastic Agents; Azacitidine; Core Binding Factor Alpha 2 Subunit; Decitabine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Drug Resistance, Neoplasm; Gene Expression Regulation, Leukemic; Histone Deacetylases; HL-60 Cells; Humans; K562 Cells; Leukemia, Promyelocytic, Acute; Oncogene Proteins, Fusion; Promoter Regions, Genetic; Receptors, Retinoic Acid; RNA, Messenger; RNA, Neoplasm; RUNX1 Translocation Partner 1 Protein; Translocation, Genetic; Tretinoin; U937 Cells | 2006 |
Differentiation-promoting drugs up-regulate NKG2D ligand expression and enhance the susceptibility of acute myeloid leukemia cells to natural killer cell-mediated lysis.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Bryostatins; Cell Differentiation; Cell Line, Tumor; Cholecalciferol; Cytotoxicity, Immunologic; Decitabine; Flow Cytometry; GPI-Linked Proteins; Humans; Hydroxamic Acids; Intercellular Signaling Peptides and Proteins; Killer Cells, Natural; Leukemia, Myeloid; Reverse Transcriptase Polymerase Chain Reaction; Tretinoin; Up-Regulation | 2007 |
High-resolution analysis of 3p deletion in neuroblastoma and differential methylation of the SEMA3B tumor suppressor gene.
Topics: Adolescent; Antineoplastic Agents; Azacitidine; Base Sequence; Cell Differentiation; Cell Line; Cell Line, Tumor; Child; Child, Preschool; Chromosome Breakage; Chromosome Deletion; Chromosomes, Human, Pair 3; CpG Islands; Decitabine; DNA Methylation; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Infant; Membrane Glycoproteins; Molecular Sequence Data; Neuroblastoma; Nucleic Acid Hybridization; Reverse Transcriptase Polymerase Chain Reaction; Semaphorins; Tretinoin | 2007 |
The comparative effects of gene modulators on thyroid-specific genes and radioiodine uptake.
Topics: Aged; Apoptosis; Azacitidine; Cell Line, Tumor; Gene Expression Regulation; Humans; Hydroxamic Acids; Iodine Radioisotopes; Proteins; RNA, Messenger; Thyroid Gland; Thyroid Neoplasms; Time Factors; Tretinoin | 2007 |
The comparative effects of gene modulators on thyroid-specific genes and radioiodine uptake.
Topics: Aged; Apoptosis; Azacitidine; Cell Line, Tumor; Gene Expression Regulation; Humans; Hydroxamic Acids; Iodine Radioisotopes; Proteins; RNA, Messenger; Thyroid Gland; Thyroid Neoplasms; Time Factors; Tretinoin | 2007 |
[Epigenetic regulation of expression of retinoic acid receptor beta gene in leukemia cell].
Topics: Acetylation; Adult; Aged; Azacitidine; Chromatin Immunoprecipitation; CpG Islands; Decitabine; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Leukemic; Histones; Humans; Leukemia; Middle Aged; Receptors, Retinoic Acid; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tretinoin; U937 Cells; Valproic Acid | 2007 |
Future research directions for the treatment of AML.
Topics: Antineoplastic Agents; Azacitidine; Biomedical Research; Carbazoles; Carboplatin; Cytarabine; Daunorubicin; Decitabine; Enzyme Inhibitors; Etoposide; Flavonoids; Furans; Humans; Leukemia, Myeloid, Acute; Mitoxantrone; Piperidines; Quinolones; Staurosporine; Topotecan; Tretinoin | 2008 |
RA induces the neural-like cells generated from epigenetic modified NIH/3T3 cells.
Topics: Animals; Azacitidine; Cell Differentiation; Decitabine; DNA Methylation; Epigenesis, Genetic; Flow Cytometry; Gene Expression Profiling; Gene Expression Regulation; Immunohistochemistry; Intermediate Filament Proteins; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Mice; Nerve Tissue Proteins; Nestin; Neurons; NIH 3T3 Cells; Octamer Transcription Factor-3; Phosphopyruvate Hydratase; Proto-Oncogene Proteins c-myc; Reverse Transcriptase Polymerase Chain Reaction; SOXB1 Transcription Factors; Tretinoin | 2010 |
Epigenetic hierarchy governing Nestin expression.
Topics: Acetylation; Animals; Azacitidine; Carcinoma, Embryonal; Cell Line; Chromatin; Chromatin Immunoprecipitation; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Embryonic Stem Cells; Enhancer Elements, Genetic; Epigenesis, Genetic; Histones; Hydroxamic Acids; Intermediate Filament Proteins; Introns; Mice; Nerve Tissue Proteins; Nestin; Promoter Regions, Genetic; Transcription, Genetic; Tretinoin | 2009 |
Re-differentiation of thyroid carcinoma cell lines treated with 5-Aza-2'-deoxycytidine and retinoic acid.
Topics: Azacitidine; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Colony-Forming Units Assay; Decitabine; Fluorescent Antibody Technique; Gene Expression Regulation, Neoplastic; Humans; Organ Specificity; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Retinoic Acid Receptor gamma; Symporters; Thyroid Neoplasms; Tretinoin | 2009 |
Impact of DNA demethylation of the G0S2 gene on the transcription of G0S2 in squamous lung cancer cell lines with or without nuclear receptor agonists.
Topics: Azacitidine; Cell Cycle Proteins; Cell Line, Tumor; Chromatin Immunoprecipitation; Decitabine; DNA Methylation; DNA Modification Methylases; Gene Expression Regulation, Neoplastic; Humans; Hydroxamic Acids; Lung Neoplasms; Neoplasms, Squamous Cell; Peroxisome Proliferator-Activated Receptors; Pioglitazone; Thiazolidinediones; Transcription, Genetic; Tretinoin | 2009 |
A DNA methyltransferase inhibitor and all-trans retinoic acid reduce oral cavity carcinogenesis induced by the carcinogen 4-nitroquinoline 1-oxide.
Topics: 4-Nitroquinoline-1-oxide; Animals; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Carcinogens; Carcinoma, Squamous Cell; Cyclin-Dependent Kinase Inhibitor p16; Cyclooxygenase 2; Decitabine; DNA Modification Methylases; Female; Immunoenzyme Techniques; Mice; Mice, Inbred C57BL; Mouth Mucosa; Mouth Neoplasms; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins c-myb; Receptors, Retinoic Acid; Retinoids; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tretinoin | 2009 |
Olfactomedin 4 is a novel target gene of retinoic acids and 5-aza-2'-deoxycytidine involved in human myeloid leukemia cell growth, differentiation, and apoptosis.
Topics: Adaptor Proteins, Signal Transducing; Antineoplastic Agents; Apoptosis; Azacitidine; Blotting, Western; Cell Cycle Proteins; Cell Differentiation; Cell Proliferation; Decitabine; DNA Methylation; Electrophoretic Mobility Shift Assay; Gene Expression; Gene Expression Regulation, Neoplastic; Granulocyte Colony-Stimulating Factor; HL-60 Cells; Humans; Immunohistochemistry; Leukemia, Myeloid; Myeloid Cells; Phosphoproteins; Response Elements; Reverse Transcriptase Polymerase Chain Reaction; Tretinoin | 2010 |
Valproic acid: growth inhibition of head and neck cancer by induction of terminal differentiation and senescence.
Topics: Antineoplastic Agents; Azacitidine; Carcinoma, Squamous Cell; Cell Culture Techniques; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cellular Senescence; Decitabine; Head and Neck Neoplasms; Histone Deacetylase Inhibitors; Humans; Squamous Cell Carcinoma of Head and Neck; Tretinoin; Valproic Acid | 2012 |
The seminoma cell line TCam-2 is sensitive to HDAC inhibitor depsipeptide but tolerates various other chemotherapeutic drugs and loss of NANOG expression.
Topics: Apoptosis; Azacitidine; Cell Differentiation; Cell Line, Tumor; Decitabine; Depsipeptides; Down-Regulation; Drug Resistance, Neoplasm; Endoderm; Gene Knockdown Techniques; Histone Deacetylase Inhibitors; Histone Deacetylases; Homeodomain Proteins; Humans; Male; Nanog Homeobox Protein; Octamer Transcription Factor-3; Seminoma; SOXF Transcription Factors; Testicular Neoplasms; Transcription Factor AP-2; Tranylcypromine; Tretinoin; Up-Regulation | 2011 |
CRABP-II- and FABP5-independent all-trans retinoic acid resistance in COLO 16 human cutaneous squamous cancer cells.
Topics: Antineoplastic Agents; Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tumor; Cytochrome P-450 Enzyme System; Decitabine; DNA Methylation; Drug Resistance, Neoplasm; Fatty Acid-Binding Proteins; Humans; PPAR delta; Receptors, Retinoic Acid; Retinoic Acid 4-Hydroxylase; Skin Neoplasms; Tretinoin | 2012 |
CRABP-II methylation: a critical determinant of retinoic acid resistance of medulloblastoma cells.
Topics: Azacitidine; Base Sequence; Cell Line, Tumor; Cytochrome P-450 Enzyme System; DNA Methylation; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Medulloblastoma; Molecular Sequence Data; Promoter Regions, Genetic; Receptors, Retinoic Acid; Retinoic Acid 4-Hydroxylase; RNA, Small Interfering; Sequence Analysis, DNA; Signal Transduction; Tissue Array Analysis; Transfection; Tretinoin | 2012 |
[Decitabine inhibits cell proliferation and induces apoptosis of all-trans retinoid acid-resistant acute promyelocytic leukemia NB4-R2 cell line].
Topics: Apoptosis; Azacitidine; Cell Line, Tumor; Cell Proliferation; Decitabine; Drug Resistance, Neoplasm; Humans; Leukemia, Promyelocytic, Acute; Tretinoin | 2012 |
In vitro neuronal induction of adipose-derived stem cells and their fate after transplantation into injured mouse brain.
Topics: Adipose Tissue; Adult; Animals; Azacitidine; Brain Injuries; Brain-Derived Neurotrophic Factor; Cell Differentiation; Doublecortin Domain Proteins; Glial Cell Line-Derived Neurotrophic Factor; Humans; Intermediate Filament Proteins; Male; Mercaptoethanol; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice; Microtubule-Associated Proteins; Middle Aged; Nerve Tissue Proteins; Nestin; Neurons; Neuropeptides; Phosphopyruvate Hydratase; Receptor, trkB; Tretinoin; Tubulin | 2012 |
All-trans retinoic acid combined with 5-Aza-2'-deoxycitidine induces C/EBPα expression and growth inhibition in MLL-AF9-positive leukemic cells.
Topics: Animals; Azacitidine; CCAAT-Enhancer-Binding Protein-alpha; Cell Line, Tumor; Cell Proliferation; DNA Methylation; Drug Resistance, Neoplasm; Hematopoietic Stem Cells; Histone-Lysine N-Methyltransferase; Humans; Leukemia, Myeloid, Acute; Mice; Myeloid-Lymphoid Leukemia Protein; Nuclear Proteins; Oncogene Proteins, Fusion; Tretinoin | 2012 |
Regulation of human Cripto-1 expression by nuclear receptors and DNA promoter methylation in human embryonal and breast cancer cells.
Topics: Azacitidine; Binding Sites; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Embryonal; Cell Movement; Decitabine; DNA Methylation; DNA Modification Methylases; Dose-Response Relationship, Drug; Embryonal Carcinoma Stem Cells; Female; Gene Expression Regulation, Developmental; Gene Expression Regulation, Neoplastic; Genes, Reporter; GPI-Linked Proteins; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Intercellular Signaling Peptides and Proteins; Luciferases; MCF-7 Cells; Neoplasm Invasiveness; Neoplasm Proteins; Nuclear Receptor Subfamily 6, Group A, Member 1; Promoter Regions, Genetic; Receptors, Cytoplasmic and Nuclear; RNA Interference; RNA, Messenger; Time Factors; Tissue Array Analysis; Transcription, Genetic; Transfection; Tretinoin; Valproic Acid | 2013 |
Knock-down of PRAME increases retinoic acid signaling and cytotoxic drug sensitivity of Hodgkin lymphoma cells.
Topics: Antigens, Neoplasm; Antineoplastic Agents; Apoptosis; Azacitidine; Cell Line, Tumor; Cytochrome P-450 Enzyme System; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Hodgkin Disease; Humans; Retinoic Acid 4-Hydroxylase; RNA Interference; Signal Transduction; Tretinoin | 2013 |
[Acute myeloid leukemia].
Topics: Aminoglycosides; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Azacitidine; fms-Like Tyrosine Kinase 3; Gemtuzumab; Humans; Leukemia, Monocytic, Acute; Molecular Targeted Therapy; Tretinoin | 2012 |
Inhibitory effects of epigenetic modulators and differentiation inducers on human medulloblastoma cell lines.
Topics: Antineoplastic Agents; Azacitidine; Cell Line, Tumor; Cell Proliferation; Cerebellar Neoplasms; Decitabine; DNA Breaks, Double-Stranded; Dose-Response Relationship, Drug; Epigenesis, Genetic; Humans; Medulloblastoma; Neoplasm Grading; Tretinoin; Tumor Stem Cell Assay; Valproic Acid | 2013 |
p19-INK4d inhibits neuroblastoma cell growth, induces differentiation and is hypermethylated and downregulated in MYCN-amplified neuroblastomas.
Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Azacitidine; Cell Differentiation; Cell Line, Tumor; Child; Child, Preschool; Cyclin-Dependent Kinase Inhibitor p19; Decitabine; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Humans; Infant; Infant, Newborn; Male; N-Myc Proto-Oncogene Protein; Neoplasm Staging; Nervous System Neoplasms; Neuroblastoma; Neurons; Nuclear Proteins; Oncogene Proteins; Signal Transduction; Survival Analysis; Tretinoin | 2014 |
Decitabine and SAHA-induced apoptosis is accompanied by survivin downregulation and potentiated by ATRA in p53-deficient cells.
Topics: Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Cell Line, Tumor; Decitabine; Down-Regulation; Drug Synergism; G2 Phase Cell Cycle Checkpoints; HL-60 Cells; Humans; Hydroxamic Acids; Inhibitor of Apoptosis Proteins; Lymphocytes; M Phase Cell Cycle Checkpoints; Reactive Oxygen Species; Survivin; Tretinoin; Tumor Suppressor Protein p53; Vorinostat | 2014 |
Biomodulatory therapy induces complete molecular remission in chemorefractory acute myeloid leukemia.
Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Azacitidine; Drug Resistance, Neoplasm; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hypoglycemic Agents; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm Grading; Neoplasm Staging; Pioglitazone; Prognosis; Remission Induction; Salvage Therapy; Survival Rate; Thiazolidinediones; Tretinoin | 2015 |
Retinoic acid receptor-β gene reexpression and biological activity in SHI-1 cells after combined treatment with 5-aza-2'-deoxycytidine and all-trans retinoic acid.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Azacitidine; Cell Differentiation; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p16; Decitabine; Gene Expression Regulation, Neoplastic; Humans; Leukemia, Monocytic, Acute; Receptors, Retinoic Acid; Tretinoin | 2015 |
[BDNF secretion in human mesenchymal stem cells isolated from bone marrow, endometrium and adipose tissue].
Topics: 1-Methyl-3-isobutylxanthine; Antigens, Nuclear; Azacitidine; Biomarkers; Bone Marrow Cells; Brain-Derived Neurotrophic Factor; Bucladesine; Cell Differentiation; Endometrium; Female; Gene Expression; Glial Fibrillary Acidic Protein; Humans; Menstruation; Mesenchymal Stem Cells; Microtubule-Associated Proteins; Nerve Tissue Proteins; Neurofilament Proteins; Neurons; Subcutaneous Fat; Tretinoin; Tubulin | 2014 |
Combination of retinoic acid, dimethyl sulfoxide and 5-azacytidine promotes cardiac differentiation of human fetal liver-derived mesenchymal stem cells.
Topics: Azacitidine; Biomarkers; Cell Differentiation; Cell Shape; Dimethyl Sulfoxide; Fetus; Humans; Immunohistochemistry; Liver; Mesenchymal Stem Cells; Myocardium; Octamer Transcription Factor-3; Osteogenesis; Phenotype; Real-Time Polymerase Chain Reaction; Reproducibility of Results; Tretinoin | 2016 |
Transcription factor activating protein 2 beta (TFAP2B) mediates noradrenergic neuronal differentiation in neuroblastoma.
Topics: Adolescent; Adrenergic Neurons; Adult; Azacitidine; Cell Cycle; Cell Differentiation; Cell Line, Tumor; Child; Child, Preschool; CpG Islands; Decitabine; DNA Methylation; Dopamine beta-Hydroxylase; Down-Regulation; Gene Knockdown Techniques; Humans; Infant; Infant, Newborn; N-Myc Proto-Oncogene Protein; Neuroblastoma; Nuclear Proteins; Oncogene Proteins; Prognosis; Promoter Regions, Genetic; Repressor Proteins; RNA, Small Interfering; Transcription Factor AP-2; Tretinoin; Tyrosine 3-Monooxygenase; Up-Regulation; Young Adult | 2016 |
Combined Treatment of ATRA with Epigenetic Drugs Increases Aggressiveness of Glioma Xenografts.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Brain Neoplasms; Cell Line, Tumor; Epigenomics; Female; Glioma; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Mice, Inbred NOD; Mice, SCID; Tretinoin; Tumor Burden; Vorinostat; Xenograft Model Antitumor Assays | 2016 |
Low-dose decitabine plus all-trans retinoic acid in patients with myeloid neoplasms ineligible for intensive chemotherapy.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Decitabine; Dose-Response Relationship, Drug; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Tretinoin | 2016 |
Enhanced inhibition of clonogenic survival of human medulloblastoma cells by multimodal treatment with ionizing irradiation, epigenetic modifiers, and differentiation-inducing drugs.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cerebellar Neoplasms; Combined Modality Therapy; Decitabine; Dideoxynucleosides; Epigenesis, Genetic; Humans; Hydroxamic Acids; Medulloblastoma; Mice; Neurogenesis; Radiation-Sensitizing Agents; Resveratrol; Stilbenes; Treatment Outcome; Tretinoin; Valproic Acid; Vorinostat; Xenograft Model Antitumor Assays | 2016 |
Sensitization of retinoids and corticoids to epigenetic drugs in MYC-activated lung cancers by antitumor reprogramming.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Apoptosis; Azacitidine; Biomarkers, Tumor; Cell Proliferation; DNA Helicases; DNA Methylation; Drug Resistance, Neoplasm; Glucocorticoids; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Lung Neoplasms; Male; Mice; Mice, Nude; Mutation; Nuclear Proteins; Proto-Oncogene Proteins c-myc; Transcription Factors; Tretinoin; Tumor Cells, Cultured; Vorinostat; Xenograft Model Antitumor Assays | 2017 |
Outcome of Lower-Risk Patients With Myelodysplastic Syndromes Without 5q Deletion After Failure of Erythropoiesis-Stimulating Agents.
Topics: Aged; Aged, 80 and over; Anemia; Antilymphocyte Serum; Antineoplastic Agents; Arsenic; Azacitidine; Chromosome Deletion; Chromosomes, Human, Pair 5; Cyclosporine; Cytarabine; Decitabine; Disease Progression; Enzyme Inhibitors; Erythrocyte Transfusion; Female; Hematinics; Humans; Hydroxyurea; Immunologic Factors; Lenalidomide; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Recurrence; Retreatment; Retrospective Studies; Risk Factors; Survival Rate; Thalidomide; Treatment Failure; Tretinoin; Valproic Acid | 2017 |
Combined epigenetic and differentiation-based treatment inhibits neuroblastoma tumor growth and links HIF2α to tumor suppression.
Topics: Animals; Azacitidine; Basic Helix-Loop-Helix Transcription Factors; Cell Proliferation; Chemotherapy, Adjuvant; Decitabine; Female; Genetic Therapy; Hypoxia-Inducible Factor 1, alpha Subunit; Mice; Mice, Nude; Neuroblastoma; Tretinoin | 2017 |
[All-Trans Retinoic Acid and Decitabine Synergistically Induce Anti-Leukemia Effect on U937 Cell Line and Newly Diagnosed Elder AML Patients].
Topics: Azacitidine; Decitabine; Humans; Leukemia, Myeloid, Acute; Tretinoin; U937 Cells | 2018 |
Evaluation of a DNA demethylating agent in combination with all-trans retinoic acid for IDH1-mutant gliomas.
Topics: Animals; Azacitidine; Brain Neoplasms; DNA Methylation; Glioma; Humans; Isocitrate Dehydrogenase; Mice; Mutation; Tretinoin | 2022 |
[Acute Myeloid Leukemia - Update 2022].
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Azacitidine; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Tretinoin | 2022 |
All-trans retinoic acid enhances the cytotoxic effect of decitabine on myelodysplastic syndromes and acute myeloid leukaemia by activating the RARα-Nrf2 complex.
Topics: Aged; Animals; Antineoplastic Agents; Azacitidine; Decitabine; Humans; Leukemia, Myeloid, Acute; Mice; Myelodysplastic Syndromes; NF-E2-Related Factor 2; Reactive Oxygen Species; Tretinoin | 2023 |
Tretinoin Enhances the Effects of Chemotherapy in Juvenile Myelomonocytic Leukemia Using an Ex Vivo Drug Sensitivity Assay.
Topics: Azacitidine; Child; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myelomonocytic, Juvenile; Tretinoin | 2023 |