azacitidine and tretinoin

azacitidine has been researched along with tretinoin in 92 studies

Research

Studies (92)

TimeframeStudies, this research(%)All Research%
pre-19909 (9.78)18.7374
1990's9 (9.78)18.2507
2000's34 (36.96)29.6817
2010's34 (36.96)24.3611
2020's6 (6.52)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Parker, RF; Scott, RE; Wang, H; Witte, MM1
Hirano, T; Kaisho, T; Nakajima, K; Oritani, K1
Miller, K; Pak, CH; Poduslo, SE1
Doré, BT; Momparler, LF; Momparler, RL1
Hassan, HT; Maurer, HR; Veit, A1
Hall, RE; Leftwich, JA1
Boeije, LC; de Waal, F; Levva, A; Pinedo, HM; Schwartsmann, G1
Leyva, A; Pinedo, HM; Schwartsmann, G1
Allalouf, D; Friedman, J; Levinsky, H; Seger, M1
Pierce, GB; Speers, WC1
Behnke, O; Olsson, L; Sørensen, HR1
Heidelberger, C; Mondal, S1
Ishida, H; Niwa, O; Sugahara, T; Yokota, Y1
Grisham, JW; Nelson, KG; Tsao, MS1
Lee, CH; Wei, LN1
Bulic-Jakus, F; Crnek, V; Skreb, N; Stepic, J; Vlahovic, M1
Côté, S; Momparler, RL1
Rutledge, JC1
Ferguson, AT; Orlandi, R; Sacchi, N; Sirchia, SM; Sironi, E; Subramanyan, S; Sukumar, S1
Arapshian, A; Kuppumbatti, YS; Mira-y-Lopez, R1
Hayashi, Y; Honma, Y; Niitsu, N; Sugita, K1
Angliker, H; Benjamin, D; Jost, JP; Siegmann, M; Thiry, S; Zheng, Y; Zhu, B1
Marx, J1
Corsaro, M; Di Croce, L; Fanelli, M; Faretta, M; Fazi, F; Fuks, F; Kouzarides, T; Lo Coco, F; Minucci, S; Nervi, C; Pelicci, PG; Raker, VA1
Hofmann, WK; Koeffler, HP1
Carpenter, MK; Police, S; Rao, N; Xu, C1
Maatouk, DM; Resnick, JL1
Andrews, LG; Hansen, NJ; Key, JS; Lopatina, NG; Pita, MA; Poole, JC; Saldanha, SN; Tollefsbol, TO1
Chen, XQ; Garcia-Manero, G; Higuchi, E; Issa, JP; Kondo, Y; Lotan, R; Youssef, EM1
Allemanni, G; Banelli, B; Brignole, C; Casciano, I; Croce, M; De Ambrosis, A; di Vinci, A; Ferrini, S; Gelvi, I; Pagnan, G; Ponzoni, M; Romani, M1
Gudas, LJ; Mongan, NP1
Andollo, N; Andrade, R; Aréchaga, J; Arlucea, J; Asumendi, A; Boyano, MD; Eguizabal, C; Zalduendo, MM1
Choi, EJ; Kim, JS; Kim, YH; Seo, JH; Whang, YM; Yoo, YD1
Doenecke, D; Happel, N; Schulze, E1
Brooks, JD; Kaygusuz, G; Kim, H; Lapointe, J; Li, C; Ong, DE; Pollack, JR; van de Rijn, M1
Cao, F; Gambhir, SS; Gonzalgo, ML; Krishnan, M; Park, JM; Paulmurugan, R; Tseng, JR; Wang, D; Wu, JC1
Lippman, SM; Sabichi, AL; Xu, X1
Biddle, A; Bounds, R; Dmitrovsky, E; Dragnev, KH; Freemantle, SJ; Li, N; Ma, Y; Nitkin, C; Petty, WJ1
Chan, WW; Chim, CS; Kwong, YL; Pang, A1
Andreeff, M; Contractor, R; Issa, JP; Jin, L; Kondo, Y; Konopleva, M; Miyake, K; Miyake, N; Nagaoka, I; Ohsaka, A; Ruvolo, V; Tabe, Y; Tsutsumi-Ishii, Y1
Kalberer, CP; Langenkamp, U; Rohner, A; Siegler, U; Wodnar-Filipowicz, A1
Cohn, SL; Cornell, J; McArdle, L; Nair, PN; Stallings, RL1
Cortes, J; Estey, EH; Estrov, Z; Faderl, S; Garcia-Manero, G; Giles, F; Issa, JP; Kantarjian, HM; Ouzounian, S; Pierce, S; Quezada, A; Ravandi, F; Soriano, AO; Wierda, WG; Yang, H1
Aydin, D; Doğan, AL; Güç, D; Taşbasan, B; Tazebay, UH; Tuncel, M; Uğur, O; Yaman, E2
Ai, GW; Liu, W; Ma, XX; Meng, XQ; Meng, YS; Wei, R; Zhang, YX1
Karp, J1
Jin, LH; Lei, L; Li, QM; Shan, ZY; Su, DJ; Wang, N; Zhang, XM1
Araúzo-Bravo, MJ; Do, JT; Han, DW; Jaenisch, R; Lee, HT; Lee, SH; Meissner, A; Schöler, HR1
Agate, L; Capodanno, A; Ciampi, R; Collecchi, P; Elisei, R; Miasaki, FY; Pinchera, A; Vivaldi, A1
Aki, N; Emoto, N; Kage, H; Kusakabe, M; Nagase, T; Nakajima, J; Ohishi, N; Takai, D; Watanabe, K; Yatomi, Y1
Albert, M; Gudas, LJ; Scognamiglio, T; Tang, XH1
Lee, HW; Liu, W; Liu, Y; Rodgers, GP; Wang, R1
Calin, GA; Fang, Z; Garcia-Manero, G; Hu, Y; Kantarjian, HM; Wei, Y; Yang, H1
Boëlle, PY; Chevret, S; Chomienne, C; Cras, A; Daniel, MT; de Labarthe, A; Degos, L; Dombret, H; Fenaux, P; Gardin, C; Maarek, O; Malfuson, JV; Marolleau, JP; Maury, S; Raffoux, E; Recher, C; Reman, O; Rousselot, P; Turlure, P; Victor, M1
Cheong, SC; Gan, CP; Hamid, S; Hor, SY; Ismail, SM; Saunders, N; Teo, SH; Wan Mustafa, WM; Zain, RB1
Biermann, K; Gillis, A; Looijenga, LH; Nettersheim, D; Schorle, H1
Chen, NN; Chen, XY; Fu, YS; Kong, QY; Li, H; Li, Y; Liu, J; Liu, ZL; Wu, ML1
Chen, NN; Chen, XY; Fu, YS; Kong, QY; Li, H; Liu, J; Ma, JX; Shu, XH; Sun, Y; Wang, Q; Wu, ML; Yang, XH; Zhang, KL1
Chen, JJ; Chen, Y; Lin, DJ; Long, ZJ; Wu, X; Xiao, RZ; Xiong, MJ1
Kalinina, N; Lopatina, T; Parfyonova, Y; Pavlova, G; Revishchin, A; Rybalkina, E; Tkachuk, V1
Fujiki, A; Hirashima, Y; Hosoi, H; Imamura, T; Kawashima, S; Miyachi, M; Nakatani, T; Sakamoto, K; Sugita, K; Yagyu, S; Yoshida, H1
Baraty, C; Bianco, C; Castro, NP; Gonzales, M; Held, N; Karasawa, H; Rangel, MC; Rollman, K; Salomon, DS; Strizzi, L1
Kewitz, S; Staege, MS1
Kurokawa, M; Nannya, Y1
Glasow, A; Kortmann, RD; Patties, I1
Bannert, S; Bender, S; Benner, A; Dreidax, D; Duffy, D; Ehemann, V; Fischer, M; Henrich, KO; Lindner, S; Oakes, CC; Pfister, S; Saadati, M; Schröder, C; Schulte, JH; Schwarzl, T; Westermann, F1
Brodská, B; Holoubek, A; Otevřelová, P1
Haferlach, T; Herr, W; Klobuch, S; Rehli, M; Reichle, A; Schelker, R; Thomas, S; Troppmann, M; Zaiss, S1
Cen, J; Chen, Z; Gu, W; Hu, S; Qiu, G; Wang, R; Wei, J; Xiang, L; Xie, X1
Anisimov, SV; Domnina, AP; Fridlianskaia, II; Grinchuk, TM; Kovaleva, ZV; Kozhukharova, IV; Nikol'skiĭ, NN; Pugovkina, NA; Puzanov, MV; Zemel'ko, VI1
Cieslik, C; Döhner, K; Grishina, O; Hackanson, B; Lübbert, M; Lubrich, B; May, AM; Müller, MJ; Schmoor, C1
Chang, J; Deng, F; Feng, P; Feng, R; Fu, H; He, L; Hu, Y; Huang, W; Lei, H; Wang, X1
Ackermann, S; Berthold, F; Dreidax, D; Engesser, A; Fischer, M; Henrich, KO; Hero, B; Hertwig, F; Ikram, F; Kahlert, Y; Kocak, H; Nürnberg, P; Roels, F; Volland, R; Westermann, F1
Beckhove, P; Gal, Z; Grabe, N; Herold-Mende, C; Lahrmann, B; Lasitschka, F; Mock, A; Mossemann, J; Schmezer, P; Schmoch, T; Unterberg, A1
Dong, W; Gu, W; Hua, X; Li, H; Lin, Y; Ling, Y; Wu, W; Xiang, L; Xie, X; Yan, F1
Glasow, A; Kortmann, RD; Menzel, F; Patties, I1
Condom, E; Esteller, M; Gomez, A; Moran, S; Romero, OA; Sanchez-Cespedes, M; Torres-Diz, M; Verdura, S; Villanueva, A1
Balleari, E; Bernal, T; Beyne-Rauzy, O; Bordessoule, D; Calabuig, M; Cametti, G; Campelo, MD; Cheze, S; Cony-Makhoul, P; Dreyfus, F; Fenaux, P; Fensterl, J; Ferrero, D; Gaidano, G; Germing, U; Gioia, D; Götze, K; Guerci-Bresler, A; Hamel, JF; Kaivers, J; Kelaidi, C; Komrokji, R; Kotsianidis, I; Müller-Thomas, C; Pane, F; Park, S; Ramos, F; Roboz, GJ; Rose, C; Sanna, A; Santini, V; Sanz, GF; Sapena, R; Sekeres, MA; Stamatoullas, A; Steensma, DP; Thépot, S; Toma, A; Vey, N; Wattel, E1
Fell, SM; Holmberg, J; Kogner, P; Li, S; Nyman, U; Schlisio, S; Shi, Y; Södersten, E; Surova, O; Toskas, K; Westerlund, I1
Cao, Y; Cen, JN; Dong, WM; Gu, WY; Lin, Y; Liu, Y; Xiang, LL; Xie, XB1
Naoe, T1
da Costa Rosa, M; Riggins, GJ; Yamashita, AS1
Herold, T; Hiddemann, W; Rausch, C; Spiekermann, K; von Bergwelt-Baildon, M1
Han, Y; Jiang, L; Jin, J; Lang, W; Li, K; Lin, P; Liu, X; Lu, C; Luo, Y; Ma, L; Mei, C; Ren, Y; Shen, C; Sun, J; Tong, H; Wang, L; Wang, Y; Xu, G; Yang, H; Yang, W; Ye, L; Ye, X; Zhang, H; Zhang, Q; Zhang, X; Zhou, X; Zhu, S1
Al-Ali, HK; Becker, H; Brugger, W; Bug, G; Crysandt, M; De Wit, M; Döhner, H; Döhner, K; Duyster, J; Ganser, A; Giagounidis, A; Götze, KS; Grishina, O; Hackanson, B; Heil, G; Heuser, M; Krauter, J; Kündgen, A; Lübbert, M; May, AM; Müller-Tidow, C; Neubauer, A; Rummelt, C; Salih, HR; Schlenk, RF; Schmoor, C; Scholl, S; Wäsch, R1
Ali, KA; Anderson, E; Anderson, W; Dhar, A; Gu, CJ; Hübner, J; Kita, R; Lacher, MD; Loh, ML; Richardson, M; Santaguida, MT; Stieglitz, E; Strachan, DC; Tasian, SK; Yam, G1

Reviews

4 review(s) available for azacitidine and tretinoin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Tumors as caricatures of the process of tissue renewal: prospects for therapy by directing differentiation.
    Cancer research, 1988, Apr-15, Volume: 48, Issue:8

    Topics: Azacitidine; Cell Differentiation; Colony-Stimulating Factors; Embryonic Induction; Humans; Neoplasms; Peptides; Transforming Growth Factors; Tretinoin

1988
Developmental toxicity induced during early stages of mammalian embryogenesis.
    Mutation research, 1997, Dec-12, Volume: 396, Issue:1-2

    Topics: Abnormalities, Drug-Induced; Animals; Azacitidine; Blastocyst; Embryonic and Fetal Development; Gene Expression Regulation, Developmental; Mammals; Mice; Mutagens; Teratogens; Tretinoin; Xenobiotics; Zygote

1997
<Editors' Choice> How to improve outcomes of elderly patients with acute myeloid leukemia: era of excitement.
    Nagoya journal of medical science, 2020, Volume: 82, Issue:2

    Topics: Aged; Aged, 80 and over; Aminopyridines; Aniline Compounds; Antineoplastic Agents; Arsenic Trioxide; Azacitidine; Benzimidazoles; Bridged Bicyclo Compounds, Heterocyclic; Decitabine; fms-Like Tyrosine Kinase 3; Humans; Isocitrate Dehydrogenase; Leukemia, Myeloid, Acute; Molecular Targeted Therapy; Phenylurea Compounds; Precision Medicine; Proto-Oncogene Proteins c-bcl-2; Pyrazines; Smoothened Receptor; Staurosporine; Sulfonamides; Survival Rate; Tretinoin; Triazines

2020

Trials

5 trial(s) available for azacitidine and tretinoin

ArticleYear
Safety and clinical activity of the combination of 5-azacytidine, valproic acid, and all-trans retinoic acid in acute myeloid leukemia and myelodysplastic syndrome.
    Blood, 2007, Oct-01, Volume: 110, Issue:7

    Topics: Acetylation; Adolescent; Adult; Aged; Aged, 80 and over; Azacitidine; Child; Child, Preschool; DNA Methylation; Dose-Response Relationship, Drug; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Gene Expression Regulation; Histones; Humans; Leukemia, Myeloid, Acute; Middle Aged; Myelodysplastic Syndromes; RNA, Messenger; Tretinoin; Valproic Acid

2007
Levels of miR-29b do not predict for response in patients with acute myelogenous leukemia treated with the combination of 5-azacytidine, valproic acid, and ATRA.
    American journal of hematology, 2011, Volume: 86, Issue:2

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cohort Studies; Gene Expression Regulation, Neoplastic; Humans; Leukemia, Myeloid, Acute; Leukocytes, Mononuclear; MicroRNAs; Myelodysplastic Syndromes; Treatment Outcome; Tretinoin; Valproic Acid

2011
Phase 2 clinical trial of 5-azacitidine, valproic acid, and all-trans retinoic acid in patients with high-risk acute myeloid leukemia or myelodysplastic syndrome.
    Oncotarget, 2010, Volume: 1, Issue:1

    Topics: Aged; Aged, 80 and over; Anticonvulsants; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; DNA Methylation; DNA, Neoplasm; Epigenomics; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Polymerase Chain Reaction; Survival Rate; Treatment Outcome; Tretinoin; Valproic Acid

2010
DECIDER: prospective randomized multicenter phase II trial of low-dose decitabine (DAC) administered alone or in combination with the histone deacetylase inhibitor valproic acid (VPA) and all-trans retinoic acid (ATRA) in patients >60 years with acute mye
    BMC cancer, 2015, May-26, Volume: 15

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Clinical Protocols; Decitabine; Female; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Tretinoin; Valproic Acid

2015
Activity of decitabine combined with all-
    Haematologica, 2023, 08-01, Volume: 108, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Decitabine; Humans; Leukemia, Myeloid, Acute; Tretinoin

2023

Other Studies

83 other study(ies) available for azacitidine and tretinoin

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Repression of SV40 T oncoprotein expression by DMSO.
    Journal of cellular physiology, 1992, Volume: 151, Issue:1

    Topics: Acetamides; Animals; Antigens, Polyomavirus Transforming; Azacitidine; Blotting, Northern; Blotting, Western; Butyrates; Butyric Acid; Cell Line, Transformed; Cell Transformation, Neoplastic; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Insulin; Interferons; Mice; Phenotype; Stem Cells; T-Lymphocytes; Tretinoin

1992
Retinoic acid inhibits interleukin-6-induced macrophage differentiation and apoptosis in a murine hematopoietic cell line, Y6.
    Blood, 1992, Nov-01, Volume: 80, Issue:9

    Topics: Animals; Apoptosis; Azacitidine; Blotting, Northern; Cell Differentiation; Cell Division; Cell Line; Cycloheximide; Dimethyl Sulfoxide; DNA; Gene Expression; Genes, jun; Genes, myc; Hematopoietic Stem Cells; Interleukin-6; Kinetics; Macrophages; Mice; Mice, Inbred BALB C; RNA; Tetradecanoylphorbol Acetate; Tretinoin

1992
Induction of cerebroside synthesis in oligodendroglia.
    Neurochemical research, 1990, Volume: 15, Issue:7

    Topics: Animals; Animals, Newborn; Azacitidine; Brain; Cattle; Cells, Cultured; Cerebrosides; Hydrocortisone; Ketone Bodies; Myelin Sheath; Oligodendroglia; Phorbol Esters; Rats; Tretinoin; Triiodothyronine

1990
Effect of 5-aza-2'-deoxycytidine and retinoic acid on differentiation and c-myc expression in HL-60 myeloid leukemic cells.
    Cancer letters, 1990, Oct-08, Volume: 54, Issue:1-2

    Topics: Antineoplastic Agents; Azacitidine; Cell Differentiation; Cell Division; Decitabine; Drug Synergism; Gene Expression; Humans; Proto-Oncogene Proteins c-myc; Tretinoin; Tumor Cells, Cultured

1990
Synergistic interactions between differentiation-inducing agents in inhibiting the proliferation of HL-60 human myeloid leukaemia cells in clonogenic micro assays.
    Journal of cancer research and clinical oncology, 1991, Volume: 117, Issue:3

    Topics: Acetamides; Aged; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cell Differentiation; Cell Division; Drug Synergism; Humans; Leukemia, Myeloid, Acute; Tretinoin; Tumor Cells, Cultured; Tumor Stem Cell Assay

1991
Enhancement of phorbol diester-induced HL-60-mediated cytotoxicity by retinoic acid, dimethyl sulfoxide, and 5-azacytidine.
    Cancer research, 1986, Volume: 46, Issue:8

    Topics: Azacitidine; Cell Differentiation; Cell Line; Cytotoxicity, Immunologic; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Leukemia, Myeloid, Acute; Macrophages; Monocytes; Phorbol 12,13-Dibutyrate; Phorbol Esters; Tetradecanoylphorbol Acetate; Tretinoin

1986
Growth inhibitory effects of 5-aza-2'-deoxycytidine in HL-60 promyelocytic leukemia cells resistant to differentiation induction.
    Biochemical and biophysical research communications, 1986, Dec-15, Volume: 141, Issue:2

    Topics: Azacitidine; Cell Cycle; Cell Differentiation; Cell Division; Cell Line; Decitabine; Dimethyl Sulfoxide; Humans; Nitroblue Tetrazolium; Tretinoin

1986
Resistance of HL-60 promyelocytic leukemia cells to induction of differentiation and its reversal by combination treatment.
    European journal of cancer & clinical oncology, 1987, Volume: 23, Issue:6

    Topics: Antineoplastic Agents; Azacitidine; Cell Differentiation; Cell Line; Decitabine; Dimethyl Sulfoxide; Drug Synergism; Humans; Leukemia, Myeloid, Acute; Tretinoin

1987
Modulation of carcinoembryonic antigen release by HT-29 colon carcinoma line in the presence of different agents.
    Experientia, 1987, Oct-15, Volume: 43, Issue:10

    Topics: Acetamides; Azacitidine; Butyrates; Butyric Acid; Carcinoembryonic Antigen; Cell Differentiation; Colonic Neoplasms; Drug Synergism; Formamides; Humans; Tetradecanoylphorbol Acetate; Tretinoin

1987
Modulatory effects of 5-azacytidine, phorbol ester, and retinoic acid on the malignant phenotype of human lung cancer cells.
    International journal of cancer, 1985, Feb-15, Volume: 35, Issue:2

    Topics: Animals; Azacitidine; Carcinoma, Small Cell; Cell Line; Clone Cells; Humans; Lung Neoplasms; Mice; Mice, Nude; Mitosis; Neoplasm Transplantation; Phenotype; Phorbols; Tetradecanoylphorbol Acetate; Tretinoin

1985
Inhibition of induced differentiation of C3H/10T 1/2 clone 8 mouse embryo cells by tumor promoters.
    Cancer research, 1980, Volume: 40, Issue:2

    Topics: Animals; Antipain; Azacitidine; Cell Differentiation; Clone Cells; Embryo, Mammalian; Epidermal Growth Factor; Mice; Muscles; Phorbol Esters; Phorbols; Tetradecanoylphorbol Acetate; Tretinoin

1980
Independent mechanisms involved in suppression of the Moloney leukemia virus genome during differentiation of murine teratocarcinoma cells.
    Cell, 1983, Volume: 32, Issue:4

    Topics: Animals; Azacitidine; Bromodeoxyuridine; Cell Cycle; Cell Differentiation; Cell Line; DNA, Viral; Gene Expression Regulation; Genes, Viral; Methylation; Mice; Moloney murine leukemia virus; Recombination, Genetic; Teratoma; Transcription, Genetic; Transfection; Tretinoin

1983
Biochemical effects of 12-O-tetradecanoylphorbol-13-acetate, retinoic acid, phenobarbital, and 5-azacytidine on a normal rat liver epithelial cell line.
    Journal of cellular physiology, 1984, Volume: 121, Issue:1

    Topics: Animals; Azacitidine; Cell Division; Cells, Cultured; Fibronectins; Liver; Phenobarbital; Phorbols; Rats; Tetradecanoylphorbol Acetate; Tretinoin

1984
Demethylation in the 5'-flanking region of mouse cellular retinoic acid binding protein-I gene is associated with its high level of expression in mouse embryos and facilitates its induction by retinoic acid in P19 embryonal carcinoma cells.
    Developmental dynamics : an official publication of the American Association of Anatomists, 1994, Volume: 201, Issue:1

    Topics: Animals; Azacitidine; Base Sequence; Carcinoma, Embryonal; Deoxyribonuclease HpaII; Deoxyribonucleases, Type II Site-Specific; DNA; Embryonic and Fetal Development; Gene Expression Regulation, Developmental; Methylation; Mice; Molecular Sequence Data; Promoter Regions, Genetic; Receptors, Retinoic Acid; Restriction Mapping; RNA, Messenger; Transcription, Genetic; Tretinoin; Tumor Cells, Cultured; Up-Regulation

1994
Differentiation and growth of rat egg-cylinders cultured in vitro in a serum-free and protein-free medium.
    The International journal of developmental biology, 1993, Volume: 37, Issue:1

    Topics: Animals; Azacitidine; Cell Differentiation; Culture Media; Culture Media, Serum-Free; Embryo, Mammalian; Female; In Vitro Techniques; Proteins; Rats; Rats, Inbred F344; Serum Albumin, Bovine; Transferrin; Tretinoin

1993
Activation of the retinoic acid receptor beta gene by 5-aza-2'-deoxycytidine in human DLD-1 colon carcinoma cells.
    Anti-cancer drugs, 1997, Volume: 8, Issue:1

    Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Antineoplastic Agents; Azacitidine; Blotting, Northern; Blotting, Southern; Cell Line; Colonic Neoplasms; Decitabine; DNA Methylation; Exons; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Receptors, Retinoic Acid; Tretinoin; Tumor Stem Cell Assay

1997
Evidence of epigenetic changes affecting the chromatin state of the retinoic acid receptor beta2 promoter in breast cancer cells.
    Oncogene, 2000, Mar-16, Volume: 19, Issue:12

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Breast; Breast Neoplasms; Cell Line; Chromatin; CpG Islands; Decitabine; DNA Methylation; Enzyme Inhibitors; Epithelial Cells; Female; Gene Expression Regulation; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Promoter Regions, Genetic; Receptors, Estrogen; Receptors, Retinoic Acid; Tretinoin; Tumor Cells, Cultured

2000
Methylation of conserved CpG sites neighboring the beta retinoic acid response element may mediate retinoic acid receptor beta gene silencing in MCF-7 breast cancer cells.
    Oncogene, 2000, Aug-17, Volume: 19, Issue:35

    Topics: Adenocarcinoma; Azacitidine; Base Sequence; Breast Neoplasms; Clone Cells; CpG Islands; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Reporter; Humans; Molecular Sequence Data; Neoplasm Proteins; Promoter Regions, Genetic; Receptors, Retinoic Acid; Sequence Analysis, DNA; Transcriptional Activation; Transfection; Tretinoin; Tumor Cells, Cultured

2000
Sensitization by 5-aza-2'-deoxycytidine of leukaemia cells with MLL abnormalities to induction of differentiation by all-trans retinoic acid and 1alpha,25-dihydroxyvitamin D3.
    British journal of haematology, 2001, Volume: 112, Issue:2

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Calcitriol; Cell Differentiation; Chromosome Breakage; Chromosomes, Human, Pair 11; Decitabine; DNA Methylation; DNA-Binding Proteins; Histone-Lysine N-Methyltransferase; Humans; Leukemia; Myeloid-Lymphoid Leukemia Protein; Proto-Oncogenes; Transcription Factors; Tretinoin; Tumor Cells, Cultured

2001
Overexpression of 5-methylcytosine DNA glycosylase in human embryonic kidney cells EcR293 demethylates the promoter of a hormone-regulated reporter gene.
    Proceedings of the National Academy of Sciences of the United States of America, 2001, Apr-24, Volume: 98, Issue:9

    Topics: Azacitidine; Blotting, Southern; Cell Line; DNA Glycosylases; DNA Methylation; Ecdysterone; Enhancer Elements, Genetic; Gene Amplification; Gene Dosage; Gene Expression Regulation; Gene Silencing; Genes, Reporter; Hormones; Humans; Kidney; Macromolecular Substances; Mutation; N-Glycosyl Hydrolases; Precipitin Tests; Promoter Regions, Genetic; Receptors, Retinoic Acid; Response Elements; Retinoid X Receptors; Transcription Factors; Transfection; Transgenes; Tretinoin

2001
Cancer research. Leukemia protein spurs gene silencing.
    Science (New York, N.Y.), 2002, Feb-08, Volume: 295, Issue:5557

    Topics: Azacitidine; Cell Division; Cell Transformation, Neoplastic; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Gene Silencing; Genes, Tumor Suppressor; Humans; Leukemia, Promyelocytic, Acute; Leukocytes; Mutation; Neoplasm Proteins; Oncogene Proteins, Fusion; Promoter Regions, Genetic; Receptors, Retinoic Acid; Tretinoin; Zinc

2002
Methyltransferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor.
    Science (New York, N.Y.), 2002, Feb-08, Volume: 295, Issue:5557

    Topics: Azacitidine; Binding Sites; Cell Differentiation; Cell Line; Cell Nucleus; Cell Transformation, Neoplastic; Cloning, Molecular; CpG Islands; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; Exons; Gene Expression; Gene Silencing; Histone Deacetylases; Humans; Leukemia, Promyelocytic, Acute; Mutation; Neoplasm Proteins; Oncogene Proteins, Fusion; Promoter Regions, Genetic; Receptors, Retinoic Acid; Recombinant Fusion Proteins; Transcription Factors; Tretinoin; Tumor Cells, Cultured; Zinc

2002
Differentiation therapy for myelodysplastic syndrome.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2002, Volume: 8, Issue:4

    Topics: Azacitidine; Cell Differentiation; Decitabine; DNA Modification Methylases; Enzyme Inhibitors; Histone Deacetylase Inhibitors; HL-60 Cells; Humans; Myelodysplastic Syndromes; Tretinoin

2002
Characterization and enrichment of cardiomyocytes derived from human embryonic stem cells.
    Circulation research, 2002, Sep-20, Volume: 91, Issue:6

    Topics: 1-Methyl-3-isobutylxanthine; Azacitidine; Cell Differentiation; Cell Size; Decitabine; Diltiazem; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Embryo, Mammalian; Gene Expression Regulation; Humans; Immunohistochemistry; Isoproterenol; Ki-67 Antigen; Myocardium; Myosin Heavy Chains; Phenylephrine; Stem Cells; Time Factors; Tretinoin; Troponin I

2002
Continuing primordial germ cell differentiation in the mouse embryo is a cell-intrinsic program sensitive to DNA methylation.
    Developmental biology, 2003, Jun-01, Volume: 258, Issue:1

    Topics: Alkaline Phosphatase; Animals; Antigens, Nuclear; Azacitidine; Biomarkers; Cell Differentiation; Cell Division; Cells, Cultured; DNA Methylation; Female; Germ Cells; Hydroxamic Acids; Male; Meiosis; Mice; Mice, Inbred Strains; Nuclear Proteins; Oogonia; Sex Differentiation; Spermatogonia; Tetradecanoylphorbol Acetate; Tretinoin

2003
Control mechanisms in the regulation of telomerase reverse transcriptase expression in differentiating human teratocarcinoma cells.
    Biochemical and biophysical research communications, 2003, Jul-04, Volume: 306, Issue:3

    Topics: Antineoplastic Agents; Azacitidine; Catalytic Domain; Cell Differentiation; DNA (Cytosine-5-)-Methyltransferases; DNA-Binding Proteins; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Humans; Hydroxamic Acids; Methylation; Promoter Regions, Genetic; Telomerase; Teratocarcinoma; Tretinoin; Tumor Cells, Cultured

2003
Hypermethylation and silencing of the putative tumor suppressor Tazarotene-induced gene 1 in human cancers.
    Cancer research, 2004, Apr-01, Volume: 64, Issue:7

    Topics: Antineoplastic Agents; Azacitidine; Cell Division; Cell Line, Tumor; Decitabine; DNA Methylation; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Tumor Suppressor; Humans; Membrane Proteins; Neoplasms; Promoter Regions, Genetic; Protein Biosynthesis; Proteins; Receptors, Retinoic Acid; Tretinoin

2004
Caspase-8 gene expression in neuroblastoma.
    Annals of the New York Academy of Sciences, 2004, Volume: 1028

    Topics: Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Caspase 8; Caspases; Cell Line, Tumor; CpG Islands; DNA; DNA Methylation; Gene Expression Regulation, Neoplastic; Humans; Interferon-gamma; Neuroblastoma; Promoter Regions, Genetic; RNA; Tretinoin

2004
Valproic acid, in combination with all-trans retinoic acid and 5-aza-2'-deoxycytidine, restores expression of silenced RARbeta2 in breast cancer cells.
    Molecular cancer therapeutics, 2005, Volume: 4, Issue:3

    Topics: Azacitidine; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Chromatin Immunoprecipitation; Decitabine; DNA Primers; Enzyme Inhibitors; Histone Deacetylases; Histones; Humans; Receptors, Retinoic Acid; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Messenger; Time Factors; Tretinoin; Valproic Acid

2005
Structural and functional preservation of specific sequences of DNA and mRNA in apoptotic bodies from ES cells.
    Apoptosis : an international journal on programmed cell death, 2005, Volume: 10, Issue:2

    Topics: Animals; Apoptosis; Azacitidine; Biotinylation; Blotting, Northern; Blotting, Southern; Blotting, Western; Cell Differentiation; Cell Proliferation; Chromatin; Decitabine; Deoxyribonuclease I; DNA; DNA Methylation; Dose-Response Relationship, Drug; Embryo, Mammalian; Flow Cytometry; Mice; Microscopy, Electron; Models, Genetic; Propidium; Protein Biosynthesis; Protein Conformation; RNA, Messenger; Stem Cells; Time Factors; Tretinoin

2005
Hyperacetylation enhances the growth-inhibitory effect of all-trans retinoic acid by the restoration of retinoic acid receptor beta expression in head and neck squamous carcinoma (HNSCC) cells.
    Cancer chemotherapy and pharmacology, 2005, Volume: 56, Issue:5

    Topics: Acetylation; Antineoplastic Agents; Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tumor; Decitabine; DNA Methylation; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Lysine; Promoter Regions, Genetic; Receptors, Retinoic Acid; Tretinoin

2005
Characterisation of human histone H1x.
    Biological chemistry, 2005, Volume: 386, Issue:6

    Topics: Amino Acid Sequence; Animals; Azacitidine; Butyrates; Cell Line; DNA; Gene Expression Regulation; HeLa Cells; Histones; HL-60 Cells; Humans; Molecular Sequence Data; Nucleosomes; Perchlorates; Sequence Alignment; Tretinoin; U937 Cells

2005
The retinoic acid synthesis gene ALDH1a2 is a candidate tumor suppressor in prostate cancer.
    Cancer research, 2005, Sep-15, Volume: 65, Issue:18

    Topics: Aldehyde Dehydrogenase; Aldehyde Dehydrogenase 1 Family; Azacitidine; Base Sequence; Cell Line, Tumor; Decitabine; DNA Methylation; Enzyme Inhibitors; Gene Expression Profiling; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Isoenzymes; Male; Molecular Sequence Data; Neoplastic Stem Cells; Promoter Regions, Genetic; Prostate; Prostatic Neoplasms; Retinal Dehydrogenase; Tretinoin

2005
Effects of epigenetic modulation on reporter gene expression: implications for stem cell imaging.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2006, Volume: 20, Issue:1

    Topics: Animals; Azacitidine; Cell Line; Cell Proliferation; Cell Survival; DNA Methylation; DNA Modification Methylases; Epigenesis, Genetic; Gene Silencing; Genes, Reporter; Hydroxamic Acids; Luciferases, Firefly; Muscle, Skeletal; Myoblasts, Cardiac; Rats; Rats, Sprague-Dawley; Stem Cell Transplantation; Stem Cells; Tretinoin

2006
RARbeta1': primed to fight retinoid resistance in lung carcinogenesis.
    Journal of the National Cancer Institute, 2005, Nov-16, Volume: 97, Issue:22

    Topics: Alternative Splicing; Antimetabolites, Antineoplastic; Azacitidine; Cell Line, Tumor; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Protein Isoforms; Receptors, Retinoic Acid; Respiratory Mucosa; Retinoid X Receptors; Tretinoin

2005
A novel retinoic acid receptor beta isoform and retinoid resistance in lung carcinogenesis.
    Journal of the National Cancer Institute, 2005, Nov-16, Volume: 97, Issue:22

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Bone Morphogenetic Proteins; Bronchial Neoplasms; Cell Line, Tumor; DNA Methylation; Gene Expression Regulation, Neoplastic; Growth Differentiation Factor 15; GTP-Binding Proteins; Humans; Immunoblotting; Luciferases; Lung Neoplasms; Membrane Proteins; Promoter Regions, Genetic; Protein Glutamine gamma Glutamyltransferase 2; Protein Isoforms; Proto-Oncogene Proteins c-fos; Receptors, Retinoic Acid; Respiratory Mucosa; Reverse Transcriptase Polymerase Chain Reaction; Transcription, Genetic; Transfection; Transglutaminases; Tretinoin

2005
Preferential methylation of Wnt inhibitory factor-1 in acute promyelocytic leukemia: an independent poor prognostic factor.
    Leukemia, 2006, Volume: 20, Issue:5

    Topics: Adaptor Proteins, Signal Transducing; Azacitidine; Biomarkers, Tumor; Carrier Proteins; Cell Line, Tumor; Cell Proliferation; Humans; Leukemia, Promyelocytic, Acute; Methylation; Multivariate Analysis; Prognosis; Recurrence; Remission Induction; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; Risk Factors; RNA, Messenger; Sensitivity and Specificity; Survival Rate; Tretinoin; Tumor Cells, Cultured

2006
PML-RARalpha and AML1-ETO translocations are rarely associated with methylation of the RARbeta2 promoter.
    Annals of hematology, 2006, Volume: 85, Issue:10

    Topics: Antineoplastic Agents; Azacitidine; Core Binding Factor Alpha 2 Subunit; Decitabine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Drug Resistance, Neoplasm; Gene Expression Regulation, Leukemic; Histone Deacetylases; HL-60 Cells; Humans; K562 Cells; Leukemia, Promyelocytic, Acute; Oncogene Proteins, Fusion; Promoter Regions, Genetic; Receptors, Retinoic Acid; RNA, Messenger; RNA, Neoplasm; RUNX1 Translocation Partner 1 Protein; Translocation, Genetic; Tretinoin; U937 Cells

2006
Differentiation-promoting drugs up-regulate NKG2D ligand expression and enhance the susceptibility of acute myeloid leukemia cells to natural killer cell-mediated lysis.
    Leukemia research, 2007, Volume: 31, Issue:10

    Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Bryostatins; Cell Differentiation; Cell Line, Tumor; Cholecalciferol; Cytotoxicity, Immunologic; Decitabine; Flow Cytometry; GPI-Linked Proteins; Humans; Hydroxamic Acids; Intercellular Signaling Peptides and Proteins; Killer Cells, Natural; Leukemia, Myeloid; Reverse Transcriptase Polymerase Chain Reaction; Tretinoin; Up-Regulation

2007
High-resolution analysis of 3p deletion in neuroblastoma and differential methylation of the SEMA3B tumor suppressor gene.
    Cancer genetics and cytogenetics, 2007, Apr-15, Volume: 174, Issue:2

    Topics: Adolescent; Antineoplastic Agents; Azacitidine; Base Sequence; Cell Differentiation; Cell Line; Cell Line, Tumor; Child; Child, Preschool; Chromosome Breakage; Chromosome Deletion; Chromosomes, Human, Pair 3; CpG Islands; Decitabine; DNA Methylation; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Infant; Membrane Glycoproteins; Molecular Sequence Data; Neuroblastoma; Nucleic Acid Hybridization; Reverse Transcriptase Polymerase Chain Reaction; Semaphorins; Tretinoin

2007
The comparative effects of gene modulators on thyroid-specific genes and radioiodine uptake.
    Cancer biotherapy & radiopharmaceuticals, 2007, Volume: 22, Issue:2

    Topics: Aged; Apoptosis; Azacitidine; Cell Line, Tumor; Gene Expression Regulation; Humans; Hydroxamic Acids; Iodine Radioisotopes; Proteins; RNA, Messenger; Thyroid Gland; Thyroid Neoplasms; Time Factors; Tretinoin

2007
The comparative effects of gene modulators on thyroid-specific genes and radioiodine uptake.
    Cancer biotherapy & radiopharmaceuticals, 2007, Volume: 22, Issue:3

    Topics: Aged; Apoptosis; Azacitidine; Cell Line, Tumor; Gene Expression Regulation; Humans; Hydroxamic Acids; Iodine Radioisotopes; Proteins; RNA, Messenger; Thyroid Gland; Thyroid Neoplasms; Time Factors; Tretinoin

2007
[Epigenetic regulation of expression of retinoic acid receptor beta gene in leukemia cell].
    Zhonghua yi xue za zhi, 2007, Dec-25, Volume: 87, Issue:48

    Topics: Acetylation; Adult; Aged; Azacitidine; Chromatin Immunoprecipitation; CpG Islands; Decitabine; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Leukemic; Histones; Humans; Leukemia; Middle Aged; Receptors, Retinoic Acid; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tretinoin; U937 Cells; Valproic Acid

2007
Future research directions for the treatment of AML.
    Clinical advances in hematology & oncology : H&O, 2008, Volume: 6, Issue:11

    Topics: Antineoplastic Agents; Azacitidine; Biomedical Research; Carbazoles; Carboplatin; Cytarabine; Daunorubicin; Decitabine; Enzyme Inhibitors; Etoposide; Flavonoids; Furans; Humans; Leukemia, Myeloid, Acute; Mitoxantrone; Piperidines; Quinolones; Staurosporine; Topotecan; Tretinoin

2008
RA induces the neural-like cells generated from epigenetic modified NIH/3T3 cells.
    Molecular biology reports, 2010, Volume: 37, Issue:3

    Topics: Animals; Azacitidine; Cell Differentiation; Decitabine; DNA Methylation; Epigenesis, Genetic; Flow Cytometry; Gene Expression Profiling; Gene Expression Regulation; Immunohistochemistry; Intermediate Filament Proteins; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Mice; Nerve Tissue Proteins; Nestin; Neurons; NIH 3T3 Cells; Octamer Transcription Factor-3; Phosphopyruvate Hydratase; Proto-Oncogene Proteins c-myc; Reverse Transcriptase Polymerase Chain Reaction; SOXB1 Transcription Factors; Tretinoin

2010
Epigenetic hierarchy governing Nestin expression.
    Stem cells (Dayton, Ohio), 2009, Volume: 27, Issue:5

    Topics: Acetylation; Animals; Azacitidine; Carcinoma, Embryonal; Cell Line; Chromatin; Chromatin Immunoprecipitation; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Embryonic Stem Cells; Enhancer Elements, Genetic; Epigenesis, Genetic; Histones; Hydroxamic Acids; Intermediate Filament Proteins; Introns; Mice; Nerve Tissue Proteins; Nestin; Promoter Regions, Genetic; Transcription, Genetic; Tretinoin

2009
Re-differentiation of thyroid carcinoma cell lines treated with 5-Aza-2'-deoxycytidine and retinoic acid.
    Molecular and cellular endocrinology, 2009, Aug-13, Volume: 307, Issue:1-2

    Topics: Azacitidine; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Colony-Forming Units Assay; Decitabine; Fluorescent Antibody Technique; Gene Expression Regulation, Neoplastic; Humans; Organ Specificity; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Retinoic Acid Receptor gamma; Symporters; Thyroid Neoplasms; Tretinoin

2009
Impact of DNA demethylation of the G0S2 gene on the transcription of G0S2 in squamous lung cancer cell lines with or without nuclear receptor agonists.
    Biochemical and biophysical research communications, 2009, Dec-25, Volume: 390, Issue:4

    Topics: Azacitidine; Cell Cycle Proteins; Cell Line, Tumor; Chromatin Immunoprecipitation; Decitabine; DNA Methylation; DNA Modification Methylases; Gene Expression Regulation, Neoplastic; Humans; Hydroxamic Acids; Lung Neoplasms; Neoplasms, Squamous Cell; Peroxisome Proliferator-Activated Receptors; Pioglitazone; Thiazolidinediones; Transcription, Genetic; Tretinoin

2009
A DNA methyltransferase inhibitor and all-trans retinoic acid reduce oral cavity carcinogenesis induced by the carcinogen 4-nitroquinoline 1-oxide.
    Cancer prevention research (Philadelphia, Pa.), 2009, Volume: 2, Issue:12

    Topics: 4-Nitroquinoline-1-oxide; Animals; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Carcinogens; Carcinoma, Squamous Cell; Cyclin-Dependent Kinase Inhibitor p16; Cyclooxygenase 2; Decitabine; DNA Modification Methylases; Female; Immunoenzyme Techniques; Mice; Mice, Inbred C57BL; Mouth Mucosa; Mouth Neoplasms; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins c-myb; Receptors, Retinoic Acid; Retinoids; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tretinoin

2009
Olfactomedin 4 is a novel target gene of retinoic acids and 5-aza-2'-deoxycytidine involved in human myeloid leukemia cell growth, differentiation, and apoptosis.
    Blood, 2010, Dec-02, Volume: 116, Issue:23

    Topics: Adaptor Proteins, Signal Transducing; Antineoplastic Agents; Apoptosis; Azacitidine; Blotting, Western; Cell Cycle Proteins; Cell Differentiation; Cell Proliferation; Decitabine; DNA Methylation; Electrophoretic Mobility Shift Assay; Gene Expression; Gene Expression Regulation, Neoplastic; Granulocyte Colony-Stimulating Factor; HL-60 Cells; Humans; Immunohistochemistry; Leukemia, Myeloid; Myeloid Cells; Phosphoproteins; Response Elements; Reverse Transcriptase Polymerase Chain Reaction; Tretinoin

2010
Valproic acid: growth inhibition of head and neck cancer by induction of terminal differentiation and senescence.
    Head & neck, 2012, Volume: 34, Issue:3

    Topics: Antineoplastic Agents; Azacitidine; Carcinoma, Squamous Cell; Cell Culture Techniques; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cellular Senescence; Decitabine; Head and Neck Neoplasms; Histone Deacetylase Inhibitors; Humans; Squamous Cell Carcinoma of Head and Neck; Tretinoin; Valproic Acid

2012
The seminoma cell line TCam-2 is sensitive to HDAC inhibitor depsipeptide but tolerates various other chemotherapeutic drugs and loss of NANOG expression.
    Genes, chromosomes & cancer, 2011, Volume: 50, Issue:12

    Topics: Apoptosis; Azacitidine; Cell Differentiation; Cell Line, Tumor; Decitabine; Depsipeptides; Down-Regulation; Drug Resistance, Neoplasm; Endoderm; Gene Knockdown Techniques; Histone Deacetylase Inhibitors; Histone Deacetylases; Homeodomain Proteins; Humans; Male; Nanog Homeobox Protein; Octamer Transcription Factor-3; Seminoma; SOXF Transcription Factors; Testicular Neoplasms; Transcription Factor AP-2; Tranylcypromine; Tretinoin; Up-Regulation

2011
CRABP-II- and FABP5-independent all-trans retinoic acid resistance in COLO 16 human cutaneous squamous cancer cells.
    Experimental dermatology, 2012, Volume: 21, Issue:1

    Topics: Antineoplastic Agents; Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tumor; Cytochrome P-450 Enzyme System; Decitabine; DNA Methylation; Drug Resistance, Neoplasm; Fatty Acid-Binding Proteins; Humans; PPAR delta; Receptors, Retinoic Acid; Retinoic Acid 4-Hydroxylase; Skin Neoplasms; Tretinoin

2012
CRABP-II methylation: a critical determinant of retinoic acid resistance of medulloblastoma cells.
    Molecular oncology, 2012, Volume: 6, Issue:1

    Topics: Azacitidine; Base Sequence; Cell Line, Tumor; Cytochrome P-450 Enzyme System; DNA Methylation; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Medulloblastoma; Molecular Sequence Data; Promoter Regions, Genetic; Receptors, Retinoic Acid; Retinoic Acid 4-Hydroxylase; RNA, Small Interfering; Sequence Analysis, DNA; Signal Transduction; Tissue Array Analysis; Transfection; Tretinoin

2012
[Decitabine inhibits cell proliferation and induces apoptosis of all-trans retinoid acid-resistant acute promyelocytic leukemia NB4-R2 cell line].
    Zhongguo shi yan xue ye xue za zhi, 2012, Volume: 20, Issue:1

    Topics: Apoptosis; Azacitidine; Cell Line, Tumor; Cell Proliferation; Decitabine; Drug Resistance, Neoplasm; Humans; Leukemia, Promyelocytic, Acute; Tretinoin

2012
In vitro neuronal induction of adipose-derived stem cells and their fate after transplantation into injured mouse brain.
    Current medicinal chemistry, 2012, Volume: 19, Issue:30

    Topics: Adipose Tissue; Adult; Animals; Azacitidine; Brain Injuries; Brain-Derived Neurotrophic Factor; Cell Differentiation; Doublecortin Domain Proteins; Glial Cell Line-Derived Neurotrophic Factor; Humans; Intermediate Filament Proteins; Male; Mercaptoethanol; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice; Microtubule-Associated Proteins; Middle Aged; Nerve Tissue Proteins; Nestin; Neurons; Neuropeptides; Phosphopyruvate Hydratase; Receptor, trkB; Tretinoin; Tubulin

2012
All-trans retinoic acid combined with 5-Aza-2'-deoxycitidine induces C/EBPα expression and growth inhibition in MLL-AF9-positive leukemic cells.
    Biochemical and biophysical research communications, 2012, Nov-16, Volume: 428, Issue:2

    Topics: Animals; Azacitidine; CCAAT-Enhancer-Binding Protein-alpha; Cell Line, Tumor; Cell Proliferation; DNA Methylation; Drug Resistance, Neoplasm; Hematopoietic Stem Cells; Histone-Lysine N-Methyltransferase; Humans; Leukemia, Myeloid, Acute; Mice; Myeloid-Lymphoid Leukemia Protein; Nuclear Proteins; Oncogene Proteins, Fusion; Tretinoin

2012
Regulation of human Cripto-1 expression by nuclear receptors and DNA promoter methylation in human embryonal and breast cancer cells.
    Journal of cellular physiology, 2013, Volume: 228, Issue:6

    Topics: Azacitidine; Binding Sites; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Embryonal; Cell Movement; Decitabine; DNA Methylation; DNA Modification Methylases; Dose-Response Relationship, Drug; Embryonal Carcinoma Stem Cells; Female; Gene Expression Regulation, Developmental; Gene Expression Regulation, Neoplastic; Genes, Reporter; GPI-Linked Proteins; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Intercellular Signaling Peptides and Proteins; Luciferases; MCF-7 Cells; Neoplasm Invasiveness; Neoplasm Proteins; Nuclear Receptor Subfamily 6, Group A, Member 1; Promoter Regions, Genetic; Receptors, Cytoplasmic and Nuclear; RNA Interference; RNA, Messenger; Time Factors; Tissue Array Analysis; Transcription, Genetic; Transfection; Tretinoin; Valproic Acid

2013
Knock-down of PRAME increases retinoic acid signaling and cytotoxic drug sensitivity of Hodgkin lymphoma cells.
    PloS one, 2013, Volume: 8, Issue:2

    Topics: Antigens, Neoplasm; Antineoplastic Agents; Apoptosis; Azacitidine; Cell Line, Tumor; Cytochrome P-450 Enzyme System; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Hodgkin Disease; Humans; Retinoic Acid 4-Hydroxylase; RNA Interference; Signal Transduction; Tretinoin

2013
[Acute myeloid leukemia].
    Nihon rinsho. Japanese journal of clinical medicine, 2012, Volume: 70 Suppl 8

    Topics: Aminoglycosides; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Azacitidine; fms-Like Tyrosine Kinase 3; Gemtuzumab; Humans; Leukemia, Monocytic, Acute; Molecular Targeted Therapy; Tretinoin

2012
Inhibitory effects of epigenetic modulators and differentiation inducers on human medulloblastoma cell lines.
    Journal of experimental & clinical cancer research : CR, 2013, May-14, Volume: 32

    Topics: Antineoplastic Agents; Azacitidine; Cell Line, Tumor; Cell Proliferation; Cerebellar Neoplasms; Decitabine; DNA Breaks, Double-Stranded; Dose-Response Relationship, Drug; Epigenesis, Genetic; Humans; Medulloblastoma; Neoplasm Grading; Tretinoin; Tumor Stem Cell Assay; Valproic Acid

2013
p19-INK4d inhibits neuroblastoma cell growth, induces differentiation and is hypermethylated and downregulated in MYCN-amplified neuroblastomas.
    Human molecular genetics, 2014, Dec-20, Volume: 23, Issue:25

    Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Azacitidine; Cell Differentiation; Cell Line, Tumor; Child; Child, Preschool; Cyclin-Dependent Kinase Inhibitor p19; Decitabine; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Humans; Infant; Infant, Newborn; Male; N-Myc Proto-Oncogene Protein; Neoplasm Staging; Nervous System Neoplasms; Neuroblastoma; Neurons; Nuclear Proteins; Oncogene Proteins; Signal Transduction; Survival Analysis; Tretinoin

2014
Decitabine and SAHA-induced apoptosis is accompanied by survivin downregulation and potentiated by ATRA in p53-deficient cells.
    Oxidative medicine and cellular longevity, 2014, Volume: 2014

    Topics: Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Cell Line, Tumor; Decitabine; Down-Regulation; Drug Synergism; G2 Phase Cell Cycle Checkpoints; HL-60 Cells; Humans; Hydroxamic Acids; Inhibitor of Apoptosis Proteins; Lymphocytes; M Phase Cell Cycle Checkpoints; Reactive Oxygen Species; Survivin; Tretinoin; Tumor Suppressor Protein p53; Vorinostat

2014
Biomodulatory therapy induces complete molecular remission in chemorefractory acute myeloid leukemia.
    Haematologica, 2015, Volume: 100, Issue:1

    Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Azacitidine; Drug Resistance, Neoplasm; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hypoglycemic Agents; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm Grading; Neoplasm Staging; Pioglitazone; Prognosis; Remission Induction; Salvage Therapy; Survival Rate; Thiazolidinediones; Tretinoin

2015
Retinoic acid receptor-β gene reexpression and biological activity in SHI-1 cells after combined treatment with 5-aza-2'-deoxycytidine and all-trans retinoic acid.
    Acta haematologica, 2015, Volume: 133, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Azacitidine; Cell Differentiation; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p16; Decitabine; Gene Expression Regulation, Neoplastic; Humans; Leukemia, Monocytic, Acute; Receptors, Retinoic Acid; Tretinoin

2015
[BDNF secretion in human mesenchymal stem cells isolated from bone marrow, endometrium and adipose tissue].
    Tsitologiia, 2014, Volume: 56, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Antigens, Nuclear; Azacitidine; Biomarkers; Bone Marrow Cells; Brain-Derived Neurotrophic Factor; Bucladesine; Cell Differentiation; Endometrium; Female; Gene Expression; Glial Fibrillary Acidic Protein; Humans; Menstruation; Mesenchymal Stem Cells; Microtubule-Associated Proteins; Nerve Tissue Proteins; Neurofilament Proteins; Neurons; Subcutaneous Fat; Tretinoin; Tubulin

2014
Combination of retinoic acid, dimethyl sulfoxide and 5-azacytidine promotes cardiac differentiation of human fetal liver-derived mesenchymal stem cells.
    Cell and tissue banking, 2016, Volume: 17, Issue:1

    Topics: Azacitidine; Biomarkers; Cell Differentiation; Cell Shape; Dimethyl Sulfoxide; Fetus; Humans; Immunohistochemistry; Liver; Mesenchymal Stem Cells; Myocardium; Octamer Transcription Factor-3; Osteogenesis; Phenotype; Real-Time Polymerase Chain Reaction; Reproducibility of Results; Tretinoin

2016
Transcription factor activating protein 2 beta (TFAP2B) mediates noradrenergic neuronal differentiation in neuroblastoma.
    Molecular oncology, 2016, Volume: 10, Issue:2

    Topics: Adolescent; Adrenergic Neurons; Adult; Azacitidine; Cell Cycle; Cell Differentiation; Cell Line, Tumor; Child; Child, Preschool; CpG Islands; Decitabine; DNA Methylation; Dopamine beta-Hydroxylase; Down-Regulation; Gene Knockdown Techniques; Humans; Infant; Infant, Newborn; N-Myc Proto-Oncogene Protein; Neuroblastoma; Nuclear Proteins; Oncogene Proteins; Prognosis; Promoter Regions, Genetic; Repressor Proteins; RNA, Small Interfering; Transcription Factor AP-2; Tretinoin; Tyrosine 3-Monooxygenase; Up-Regulation; Young Adult

2016
Combined Treatment of ATRA with Epigenetic Drugs Increases Aggressiveness of Glioma Xenografts.
    Anticancer research, 2016, Volume: 36, Issue:4

    Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Brain Neoplasms; Cell Line, Tumor; Epigenomics; Female; Glioma; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Mice, Inbred NOD; Mice, SCID; Tretinoin; Tumor Burden; Vorinostat; Xenograft Model Antitumor Assays

2016
Low-dose decitabine plus all-trans retinoic acid in patients with myeloid neoplasms ineligible for intensive chemotherapy.
    Annals of hematology, 2016, Volume: 95, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Decitabine; Dose-Response Relationship, Drug; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Tretinoin

2016
Enhanced inhibition of clonogenic survival of human medulloblastoma cells by multimodal treatment with ionizing irradiation, epigenetic modifiers, and differentiation-inducing drugs.
    Journal of experimental & clinical cancer research : CR, 2016, 06-17, Volume: 35, Issue:1

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cerebellar Neoplasms; Combined Modality Therapy; Decitabine; Dideoxynucleosides; Epigenesis, Genetic; Humans; Hydroxamic Acids; Medulloblastoma; Mice; Neurogenesis; Radiation-Sensitizing Agents; Resveratrol; Stilbenes; Treatment Outcome; Tretinoin; Valproic Acid; Vorinostat; Xenograft Model Antitumor Assays

2016
Sensitization of retinoids and corticoids to epigenetic drugs in MYC-activated lung cancers by antitumor reprogramming.
    Oncogene, 2017, 03-02, Volume: 36, Issue:9

    Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Apoptosis; Azacitidine; Biomarkers, Tumor; Cell Proliferation; DNA Helicases; DNA Methylation; Drug Resistance, Neoplasm; Glucocorticoids; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Lung Neoplasms; Male; Mice; Mice, Nude; Mutation; Nuclear Proteins; Proto-Oncogene Proteins c-myc; Transcription Factors; Tretinoin; Tumor Cells, Cultured; Vorinostat; Xenograft Model Antitumor Assays

2017
Outcome of Lower-Risk Patients With Myelodysplastic Syndromes Without 5q Deletion After Failure of Erythropoiesis-Stimulating Agents.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2017, May-10, Volume: 35, Issue:14

    Topics: Aged; Aged, 80 and over; Anemia; Antilymphocyte Serum; Antineoplastic Agents; Arsenic; Azacitidine; Chromosome Deletion; Chromosomes, Human, Pair 5; Cyclosporine; Cytarabine; Decitabine; Disease Progression; Enzyme Inhibitors; Erythrocyte Transfusion; Female; Hematinics; Humans; Hydroxyurea; Immunologic Factors; Lenalidomide; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Recurrence; Retreatment; Retrospective Studies; Risk Factors; Survival Rate; Thalidomide; Treatment Failure; Tretinoin; Valproic Acid

2017
Combined epigenetic and differentiation-based treatment inhibits neuroblastoma tumor growth and links HIF2α to tumor suppression.
    Proceedings of the National Academy of Sciences of the United States of America, 2017, 07-25, Volume: 114, Issue:30

    Topics: Animals; Azacitidine; Basic Helix-Loop-Helix Transcription Factors; Cell Proliferation; Chemotherapy, Adjuvant; Decitabine; Female; Genetic Therapy; Hypoxia-Inducible Factor 1, alpha Subunit; Mice; Mice, Nude; Neuroblastoma; Tretinoin

2017
[All-Trans Retinoic Acid and Decitabine Synergistically Induce Anti-Leukemia Effect on U937 Cell Line and Newly Diagnosed Elder AML Patients].
    Zhongguo shi yan xue ye xue za zhi, 2018, Volume: 26, Issue:4

    Topics: Azacitidine; Decitabine; Humans; Leukemia, Myeloid, Acute; Tretinoin; U937 Cells

2018
Evaluation of a DNA demethylating agent in combination with all-trans retinoic acid for IDH1-mutant gliomas.
    Neuro-oncology, 2022, 05-04, Volume: 24, Issue:5

    Topics: Animals; Azacitidine; Brain Neoplasms; DNA Methylation; Glioma; Humans; Isocitrate Dehydrogenase; Mice; Mutation; Tretinoin

2022
[Acute Myeloid Leukemia - Update 2022].
    Deutsche medizinische Wochenschrift (1946), 2022, Volume: 147, Issue:17

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Azacitidine; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Tretinoin

2022
All-trans retinoic acid enhances the cytotoxic effect of decitabine on myelodysplastic syndromes and acute myeloid leukaemia by activating the RARα-Nrf2 complex.
    British journal of cancer, 2023, Volume: 128, Issue:4

    Topics: Aged; Animals; Antineoplastic Agents; Azacitidine; Decitabine; Humans; Leukemia, Myeloid, Acute; Mice; Myelodysplastic Syndromes; NF-E2-Related Factor 2; Reactive Oxygen Species; Tretinoin

2023
Tretinoin Enhances the Effects of Chemotherapy in Juvenile Myelomonocytic Leukemia Using an Ex Vivo Drug Sensitivity Assay.
    JCO precision oncology, 2023, Volume: 7

    Topics: Azacitidine; Child; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myelomonocytic, Juvenile; Tretinoin

2023