azacitidine and thioguanine anhydrous

azacitidine has been researched along with thioguanine anhydrous in 35 studies

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-199015 (42.86)18.7374
1990's8 (22.86)18.2507
2000's5 (14.29)29.6817
2010's6 (17.14)24.3611
2020's1 (2.86)2.80

Authors

AuthorsStudies
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Wiernik, PH1
Bear, RA; Garvey, MB; Ho, M1
Abella, E; Alvarado, CS; Chauvenet, A; Dubowy, R; Harris, M; Inoue, S; Krischer, JP; Ravindranath, Y; Ritchey, AK; Wiley, J1
Buckley, JD; Hammond, GD; Lampkin, BC; Woods, WG1
Gray, RG; Rees, JK1
Nyce, J1
Boyett, J; Kitchens, CS; Kramer, BS; Noyes, WD; Oblon, DJ; Ross, W; Weiner, RS1
Ivarie, R; Morris, JA1
Catovsky, D; Chessells, JM; Galton, DA; Goldman, JM; Hann, IM; Hoffbrand, AV; Marcus, RE; Newland, AC; Prentice, HG; Stevens, RF1
Gray, R; Hayhoe, FG; Rees, JK1
Chan, HS; Estrov, Z; Freedman, MH; Weitzman, SS1
Baehner, RL; Buckley, JD; Chard, RL; Hammond, GD; Lampkin, BC; Nesbit, ME; Woods, WG1
Brown, AG; Caspary, WJ; Cattanach, P; Daston, DS; McGregor, DB; Riach, C; Shepherd, W1
Aiba, K; Allegra, CJ; Baram, J; Chabner, BA; Curt, GA; Yeh, GC1
Baehner, RL; Bernstein, ID; Chard, RL; Hammond, D; Higgins, G; McCreadie, S; Sather, H1
Poster, DS; Weiss, RB1
Boccia, R; Champlin, R; Elashoff, R; Foon, K; Gale, RP; Jacobs, A; Zighelboim, J1
Go, B; Gordon, DS; Meyer, L; Raney, MR; Vogler, WR; Winton, EF1
Momparler, LF; Momparler, RL; Rivard, GE; Samson, J1
Christie, NT; Costa, M; Dowjat, K; Kargacin, B; Kitahara, J; Klein, CB; Lee, YW; Salnikow, K; Zhitkovich, A1
Bartolucci, AA; Moore, JO; Omura, GA; Stagg, M; Volger, WR; Weiner, RS1
Caspary, WJ; Hines, KC; Spencer, DL; Tindall, KR1
Broday, L; Costa, M; Lee, YW1
Camitta, B; Carroll, AJ; Chang, M; Gresik, MV; Raimondi, SC; Ravindranath, Y; Steuber, CP; Weinstein, H1
Barbata, G; Caradonna, F; Sciandrello, G1
Aung, L; Kirk, RC; Liang, S; Quah, TC; Tan, RM; Yeoh, AE1
Wang, H; Wang, Y1
Hucho, T; Isensee, J; Kaehler, C; Krobitsch, S; Lehrach, H1
Agrawal, K; Das, V; Hajdúch, M; Vyas, P1

Reviews

4 review(s) available for azacitidine and thioguanine anhydrous

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Antimetabolites.
    Cancer chemotherapy and biological response modifiers, 1987, Volume: 9

    Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Cytarabine; Floxuridine; Fluorouracil; Folic Acid Antagonists; Humans; Mercaptopurine; Methotrexate; Purines; Thioguanine

1987
The renal toxicity of cancer chemotherapeutic agents.
    Cancer treatment reviews, 1982, Volume: 9, Issue:1

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Azacitidine; Cisplatin; Cyclophosphamide; Dacarbazine; Humans; Kidney Diseases; Methotrexate; Mitomycins; Naphthacenes; Nitrosourea Compounds; Plicamycin; Streptozocin; Thioguanine

1982
Nucleosidic DNA demethylating epigenetic drugs - A comprehensive review from discovery to clinic.
    Pharmacology & therapeutics, 2018, Volume: 188

    Topics: Animals; Antineoplastic Agents; Azacitidine; DNA (Cytosine-5-)-Methyltransferase 1; DNA Methylation; Drug Discovery; Drug Resistance, Neoplasm; Humans; Nucleosides; Thioguanine

2018

Trials

8 trial(s) available for azacitidine and thioguanine anhydrous

ArticleYear
Preliminary results of intensive therapy of children and adolescents with acute nonlymphocytic leukemia--a Childrens Cancer Study Group report.
    Haematology and blood transfusion, 1990, Volume: 33

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Bone Marrow Transplantation; Child; Child, Preschool; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Daunorubicin; Etoposide; Humans; Infant; Leukemia, Myeloid, Acute; Multicenter Studies as Topic; Pilot Projects; Randomized Controlled Trials as Topic; Remission Induction; Thioguanine; Vincristine

1990
Remission induction and postremission therapy in acute myelogenous leukemia: British MRC Study.
    Haematology and blood transfusion, 1990, Volume: 33

    Topics: Adolescent; Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Bone Marrow Transplantation; Child; Child, Preschool; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Dacarbazine; Daunorubicin; Doxorubicin; Drug Combinations; Etoposide; Humans; Leukemia, Myeloid, Acute; Middle Aged; Mitoxantrone; Multicenter Studies as Topic; Nimustine; Prednisone; Randomized Controlled Trials as Topic; Remission Induction; Survival Rate; Thioguanine; United Kingdom; Vincristine

1990
Intensive induction and consolidation chemotherapy for adults and children with acute myeloid leukaemia (AML) joint AML trial 1982-1985.
    Haematology and blood transfusion, 1987, Volume: 30

    Topics: Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Child; Clinical Trials as Topic; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Leukemia, Myeloid, Acute; Male; Random Allocation; Remission Induction; Risk; Thioguanine; United Kingdom

1987
The ninth British Medical Research Council trial for the treatment of acute myeloid leukaemia.
    Haematology and blood transfusion, 1987, Volume: 30

    Topics: Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Clinical Trials as Topic; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Combinations; England; Etoposide; Humans; Leukemia, Myeloid, Acute; Prednisone; Remission Induction; Thioguanine; Vincristine

1987
Improvement in outcome for children with acute nonlymphocytic leukemia. A report from the Childrens Cancer Study Group.
    Cancer, 1989, Apr-15, Volume: 63, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Bone Marrow Transplantation; Child; Child, Preschool; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Humans; Infant; Leukemia, Myeloid, Acute; Leukocyte Count; Male; Prednisolone; Prognosis; Remission Induction; Thioguanine; Vincristine

1989
Contrasting benefits of two maintenance programs following identical induction in children with acute nonlymphocytic leukemia: a report from the Childrens Cancer Study Group.
    Cancer treatment reports, 1984, Volume: 68, Issue:10

    Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Child; Cyclophosphamide; Cytarabine; Humans; Leukemia; Thioguanine; Vincristine

1984
A randomized comparison of postremission therapy in acute myelogenous leukemia: a Southeastern Cancer Study Group trial.
    Blood, 1984, Volume: 63, Issue:5

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; BCG Vaccine; Clinical Trials as Topic; Combined Modality Therapy; Cytarabine; Daunorubicin; Deoxyguanosine; Female; Humans; Immunotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Random Allocation; Thioguanine; Thionucleosides; United States

1984
Long-term follow-up of a randomized post-induction therapy trial in acute myelogenous leukemia (a Southeastern Cancer Study Group trial).
    Leukemia, 1995, Volume: 9, Issue:9

    Topics: Adolescent; Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cytarabine; Daunorubicin; Female; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Patient Selection; Remission Induction; Thioguanine

1995

Other Studies

23 other study(ies) available for azacitidine and thioguanine anhydrous

ArticleYear
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
The therapy of acute leukemia in the adult: a progress report.
    Hamatologie und Bluttransfusion, 1976, Volume: 19

    Topics: Acute Disease; Adult; Antineoplastic Agents; Azacitidine; Blood Transfusion; Cytarabine; Daunorubicin; Dexamethasone; Etoposide; Granulocytes; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Patient Isolation; Platelet Transfusion; Pneumonia; Prednisone; Pyrimethamine; Remission, Spontaneous; Thioguanine; Vincristine; Zinostatin

1976
Symptomatic hypophosphatemia secondary to 5-azacytidine therapy of acute nonlymphocytic leukemia.
    Cancer treatment reports, 1976, Volume: 60, Issue:9

    Topics: Adult; Azacitidine; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia, Myeloid, Acute; Male; Phosphates; Prednisone; Pregnancy; Pregnancy Complications; Thioguanine; Vincristine

1976
Acute myeloid leukemia (AML) in Down's syndrome is highly responsive to chemotherapy: experience on Pediatric Oncology Group AML Study 8498.
    Blood, 1992, Nov-01, Volume: 80, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Antigens, CD; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Azacitidine; Child; Chromosome Aberrations; Chromosome Disorders; Cytarabine; Daunorubicin; Down Syndrome; Etoposide; Female; Follow-Up Studies; Humans; Leukemia, Myeloid; Male; Mercaptopurine; Methotrexate; Prednisone; Remission Induction; Thioguanine; Vincristine

1992
Gene silencing in mammalian cells by direct incorporation of electroporated 5-methyl-2'-deoxycytidine 5'-triphosphate.
    Somatic cell and molecular genetics, 1991, Volume: 17, Issue:6

    Topics: 5-Methylcytosine; Animals; Azacitidine; Base Composition; Cell Division; Cell Line; Cell Survival; Cricetinae; Cytosine; Deoxycytosine Nucleotides; Drug Resistance; Gene Expression Regulation; Methylation; Mutagenesis; Thioguanine

1991
Intensive short-term chemotherapy for patients with acute myelogenous leukemia: long-term follow-up.
    Cancer treatment reports, 1985, Volume: 69, Issue:12

    Topics: Actuarial Analysis; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Bone Marrow; Cytarabine; Daunorubicin; Female; Follow-Up Studies; Humans; Leukemia, Myeloid; Male; Middle Aged; Pilot Projects; Thioguanine

1985
Activation of a nonexpressed hypoxanthine phosphoribosyltransferase allele in mutant H23 HeLa cells by agents that inhibit DNA methylation.
    Molecular and cellular biology, 1986, Volume: 6, Issue:1

    Topics: Alleles; Azacitidine; Azaserine; Ethyl Methanesulfonate; Genes; HeLa Cells; Humans; Hypoxanthine Phosphoribosyltransferase; Methylation; Methylnitronitrosoguanidine; Mutation; Thioguanine

1986
The value of intensive combination chemotherapy for juvenile chronic myelogenous leukemia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1987, Volume: 5, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Child, Preschool; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Infant; Leukemia, Myeloid; Male; Mercaptopurine; Mitoxantrone; Thioguanine

1987
TFT and 6TG resistance of mouse lymphoma cells to analogs of azacytidine.
    Carcinogenesis, 1989, Volume: 10, Issue:11

    Topics: Animals; Azacitidine; Cell Differentiation; Dose-Response Relationship, Drug; Drug Resistance; Hypoxanthine Phosphoribosyltransferase; Leukemia L5178; Mice; Mutation; Thioguanine; Thymidine Kinase; Trifluridine; Tumor Cells, Cultured

1989
Prolonged survival in acute myelogenous leukaemia without maintenance chemotherapy.
    Lancet (London, England), 1984, Apr-21, Volume: 1, Issue:8382

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cytarabine; Daunorubicin; Drug Administration Schedule; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Recurrence; Thioguanine; Time Factors

1984
Cell cycle effects and cellular pharmacology of 5-aza-2'-deoxycytidine.
    Cancer chemotherapy and pharmacology, 1984, Volume: 13, Issue:3

    Topics: Animals; Azacitidine; Cell Cycle; Cell Line; Cell Survival; Decitabine; DNA Replication; Female; Mammary Neoplasms, Experimental; Mice; Mutation; Thioguanine

1984
Carcinogenic nickel silences gene expression by chromatin condensation and DNA methylation: a new model for epigenetic carcinogens.
    Molecular and cellular biology, 1995, Volume: 15, Issue:5

    Topics: Animals; Azacitidine; Base Sequence; Carcinogens; Cell Line; Chromatin; Cricetinae; Cricetulus; DNA; DNA Primers; Drug Resistance; Gene Expression; Genetic Variation; Hypoxanthine Phosphoribosyltransferase; Methylation; Models, Biological; Molecular Sequence Data; Nickel; Phenotype; Thioguanine

1995
5-Azacytidine-induced 6-thioguanine resistance at the gpt locus in AS52 cells: cellular response.
    Environmental and molecular mutagenesis, 1996, Volume: 28, Issue:2

    Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Bacterial Proteins; Cell Division; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Drug Resistance; Escherichia coli Proteins; Mutagenesis; Mutagens; Mutation; Pentosyltransferases; Proteins; Thioguanine; Time Factors

1996
5-azacytidine induces transgene silencing by DNA methylation in Chinese hamster cells.
    Molecular and cellular biology, 1999, Volume: 19, Issue:4

    Topics: Animals; Azacitidine; Base Sequence; CHO Cells; Chromatin; CpG Islands; Cricetinae; DNA Methylation; Drug Resistance; Gene Expression Regulation; Hypoxanthine Phosphoribosyltransferase; Molecular Sequence Data; Mutagenesis; Mutagens; Thioguanine; Transgenes

1999
Prognostic factors in children and adolescents with acute myeloid leukemia (excluding children with Down syndrome and acute promyelocytic leukemia): univariate and recursive partitioning analysis of patients treated on Pediatric Oncology Group (POG) Study
    Leukemia, 2000, Volume: 14, Issue:7

    Topics: Adolescent; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Bone Marrow Transplantation; Child; Chromosome Aberrations; Chromosome Inversion; Chromosomes, Human; Cohort Studies; Combined Modality Therapy; Cytarabine; Disease-Free Survival; Doxorubicin; Etoposide; Female; Follow-Up Studies; Humans; Leukemia, Myeloid; Life Tables; Male; Multicenter Studies as Topic; Prognosis; Proportional Hazards Models; Randomized Controlled Trials as Topic; Remission Induction; Risk Assessment; Risk Factors; Survival Analysis; Thioguanine; Translocation, Genetic; Treatment Failure; Treatment Outcome; United States

2000
The DNA methylation inhibitor 5-azacytidine modulates 6-thioguanine toxicity in mammalian cells.
    Toxicology letters, 2003, Apr-30, Volume: 142, Issue:1-2

    Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cell Division; Cell Survival; Cells, Cultured; Cricetinae; Cricetulus; DNA; DNA Methylation; Drug Synergism; Hypoxanthine Phosphoribosyltransferase; Sister Chromatid Exchange; Thioguanine

2003
Improved outcome in childhood acute myeloid leukemia in Singapore with the MRC AML 10 protocol.
    Pediatric blood & cancer, 2007, Volume: 48, Issue:3

    Topics: Acute Disease; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Cytarabine; Daunorubicin; Developing Countries; Disease-Free Survival; Drug Evaluation; Etoposide; Female; Gastrointestinal Diseases; Heart Diseases; Hematologic Diseases; Humans; Infant; Infections; Kaplan-Meier Estimate; Leukemia, Myeloid; Male; Mercaptopurine; Methotrexate; Mitoxantrone; Prednisone; Remission Induction; Retrospective Studies; Singapore; Survival Analysis; Thioguanine; Treatment Outcome; Vincristine

2007
6-Thioguanine perturbs cytosine methylation at the CpG dinucleotide site by DNA methyltransferases in vitro and acts as a DNA demethylating agent in vivo.
    Biochemistry, 2009, Mar-17, Volume: 48, Issue:10

    Topics: Azacitidine; Cytosine; Decitabine; Dinucleoside Phosphates; DNA; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA-Cytosine Methylases; Humans; Jurkat Cells; Oligodeoxyribonucleotides; Tandem Mass Spectrometry; Thioguanine

2009
5-Fluorouracil affects assembly of stress granules based on RNA incorporation.
    Nucleic acids research, 2014, Volume: 42, Issue:10

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Cell Line; DNA; Eukaryotic Initiation Factor-2; Fluorouracil; GTP-Binding Proteins; HeLa Cells; Humans; Neoplasm Proteins; Oxidative Stress; Receptors for Activated C Kinase; Receptors, Cell Surface; Ribonucleoproteins; RNA; Stress, Physiological; Thioguanine

2014