azacitidine and staurosporine

azacitidine has been researched along with staurosporine in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (18.75)18.2507
2000's3 (18.75)29.6817
2010's5 (31.25)24.3611
2020's5 (31.25)2.80

Authors

AuthorsStudies
Jacquemin-Sablon, A; Segal-Bendirdjian, E2
Clase, KL; Elliott, MS; Galicia, MC; Morris, RC1
Cockerell, GL; Goodman, JI; McKim, JM; Watson, RE1
Gore, SD1
Karp, J1
Büchner, T; Krug, U; Lübbert, M1
Abhyankar, S; Aljitawi, O; Bhalla, KN; Dutreix, C; Fiskus, W; Fleming, A; Ganguly, S; Kambhampati, S; McGuirk, JP; Reyes, R; Wick, J; Williams, CB1
Andreeff, M; Borthakur, G; Cortes, J; Daver, N; Durand, M; Estrov, Z; Garcia-Manero, G; Kadia, T; Kantarjian, H; Konopleva, M; Levis, M; Nazha, A; Rajkhowa, T; Ravandi, F; Strati, P1
Cooper, BW; Craig, MD; Creger, RJ; Hamadani, M; Kindwall-Keller, TL; Lazarus, HM; Tse, WW1
Liu, S; Molina, JR; Pang, J; Shen, N; Yan, F; Yang, P1
Cooper, BW; Craig, MD; Gallogly, MM; Kane, DM; Lazarus, HM; Levis, MJ; Metheny, L; Tomlinson, BK; William, BM1
Carraway, HE; Chandhok, NS; Griffiths, EA; Prebet, T1
Andrews, C; Maze, D; Murphy, T; Sibai, H1
Naoe, T1
Angelopoulou, MK; Chatzidimitriou, C; Konstantopoulos, K; Korkolopoulou, P; Lafioniatis, S; Lakiotaki, E; Pappa, V; Plata, E; Vassilakopoulos, TP1

Reviews

5 review(s) available for azacitidine and staurosporine

ArticleYear
[Cisplatin resistance in a murine leukemia cell line associated with defect of apoptosis].
    Bulletin du cancer, 1996, Volume: 83, Issue:5

    Topics: Alkaloids; Animals; Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Cell Division; Cisplatin; Clone Cells; DNA, Neoplasm; Drug Resistance, Neoplasm; Endonucleases; Leukemia L1210; Mice; Protein Kinase C; Staurosporine; Tumor Cells, Cultured

1996
Maintenance therapy in acute myeloid leukemia revisited: will new agents rekindle an old interest?
    Current opinion in hematology, 2010, Volume: 17, Issue:2

    Topics: Azacitidine; Benzenesulfonates; Decitabine; Enzyme Inhibitors; Humans; Leukemia, Myeloid, Acute; Niacinamide; Phenylurea Compounds; Prenylation; Protein-Tyrosine Kinases; Pyridines; Sorafenib; Staurosporine

2010
Advances in non-intensive chemotherapy treatment options for adults diagnosed with acute myeloid leukemia.
    Leukemia research, 2020, Volume: 91

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Benzimidazoles; Bridged Bicyclo Compounds, Heterocyclic; Cytarabine; Decitabine; Gemtuzumab; Glycine; Humans; Leukemia, Myeloid, Acute; Male; Molecular Targeted Therapy; Phenylurea Compounds; Precision Medicine; Pyridines; Recurrence; Remission Induction; Staurosporine; Sulfonamides

2020
Combination treatment with CPX-351 and midostaurin in patients with secondary acute myeloid leukaemia that are FLT3 mutated: three cases and review of literature.
    British journal of haematology, 2020, Volume: 190, Issue:3

    Topics: Aged; Allografts; Anemia, Refractory, with Excess of Blasts; Aniline Compounds; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Breast Neoplasms; Bridged Bicyclo Compounds, Heterocyclic; Clinical Trials, Phase III as Topic; Cytarabine; Daunorubicin; Fatal Outcome; Female; fms-Like Tyrosine Kinase 3; Humans; Leukemia, Myeloid, Acute; Liposomes; Male; Middle Aged; Myelodysplastic Syndromes; Neoplasm, Residual; Neoplasms, Radiation-Induced; Oncogene Proteins, Fusion; Peripheral Blood Stem Cell Transplantation; Point Mutation; Protein Kinase Inhibitors; Pyrazines; Remission Induction; Salvage Therapy; Staurosporine; Sulfonamides

2020
<Editors' Choice> How to improve outcomes of elderly patients with acute myeloid leukemia: era of excitement.
    Nagoya journal of medical science, 2020, Volume: 82, Issue:2

    Topics: Aged; Aged, 80 and over; Aminopyridines; Aniline Compounds; Antineoplastic Agents; Arsenic Trioxide; Azacitidine; Benzimidazoles; Bridged Bicyclo Compounds, Heterocyclic; Decitabine; fms-Like Tyrosine Kinase 3; Humans; Isocitrate Dehydrogenase; Leukemia, Myeloid, Acute; Molecular Targeted Therapy; Phenylurea Compounds; Precision Medicine; Proto-Oncogene Proteins c-bcl-2; Pyrazines; Smoothened Receptor; Staurosporine; Sulfonamides; Survival Rate; Tretinoin; Triazines

2020

Trials

4 trial(s) available for azacitidine and staurosporine

ArticleYear
Preclinical and phase I results of decitabine in combination with midostaurin (PKC412) for newly diagnosed elderly or relapsed/refractory adult patients with acute myeloid leukemia.
    Pharmacotherapy, 2013, Volume: 33, Issue:12

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cell Line, Tumor; Cohort Studies; Decitabine; Drug Synergism; Female; Flow Cytometry; fms-Like Tyrosine Kinase 3; Humans; Leukemia, Myeloid, Acute; Male; Maximum Tolerated Dose; Middle Aged; Mutation; Recurrence; Staurosporine

2013
Phase I/II trial of the combination of midostaurin (PKC412) and 5-azacytidine for patients with acute myeloid leukemia and myelodysplastic syndrome.
    American journal of hematology, 2015, Volume: 90, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; fms-Like Tyrosine Kinase 3; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mutation; Myelodysplastic Syndromes; Staurosporine; Young Adult

2015
A phase I study of midostaurin and azacitidine in relapsed and elderly AML patients.
    Clinical lymphoma, myeloma & leukemia, 2015, Volume: 15, Issue:7

    Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Female; fms-Like Tyrosine Kinase 3; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mutation; Neoplasm Recurrence, Local; Staurosporine; Treatment Outcome

2015
A Phase II Study of Midostaurin and 5-Azacitidine for Untreated Elderly and Unfit Patients With FLT3 Wild-type Acute Myelogenous Leukemia.
    Clinical lymphoma, myeloma & leukemia, 2020, Volume: 20, Issue:4

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Female; fms-Like Tyrosine Kinase 3; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Staurosporine

2020

Other Studies

7 other study(ies) available for azacitidine and staurosporine

ArticleYear
Cisplatin resistance in a murine leukemia cell line is associated with a defective apoptotic process.
    Experimental cell research, 1995, Volume: 218, Issue:1

    Topics: Alkaloids; Animals; Apoptosis; Azacitidine; Cell Division; Cell Nucleus; Cisplatin; Clone Cells; Cycloheximide; DNA, Neoplasm; Drug Resistance; Endonucleases; Leukemia L1210; Mice; Microscopy, Confocal; Microscopy, Electron; Protein Kinase C; Staurosporine; Tumor Cells, Cultured

1995
Determination of queuosine modification system deficiencies in cultured human cells.
    Molecular genetics and metabolism, 1999, Volume: 68, Issue:1

    Topics: Azacitidine; Cells, Cultured; Enzyme Inhibitors; Guanine; Humans; Male; Nucleoside Q; Phosphorylation; Protein Kinase C; RNA, Transfer; Staurosporine; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured

1999
The value of DNA methylation analysis in basic, initial toxicity assessments.
    Toxicological sciences : an official journal of the Society of Toxicology, 2004, Volume: 79, Issue:1

    Topics: Animals; Azacitidine; Base Composition; Cell Line, Tumor; Cytosine; DNA Methylation; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Fluorouracil; Gene Expression; Guanine; Mutagenicity Tests; Polymerase Chain Reaction; Rats; Rotenone; Staurosporine

2004
New agents for the treatment of AML recent study findings.
    Clinical advances in hematology & oncology : H&O, 2008, Volume: 6, Issue:11

    Topics: Adenine Nucleotides; Antineoplastic Agents; Arabinonucleosides; Azacitidine; Carbazoles; Clofarabine; Decitabine; Enzyme Inhibitors; Furans; Humans; Hydrazines; Immunotherapy; Lenalidomide; Leukemia, Myeloid, Acute; Quinolones; Staurosporine; Sulfonamides; Thalidomide

2008
Future research directions for the treatment of AML.
    Clinical advances in hematology & oncology : H&O, 2008, Volume: 6, Issue:11

    Topics: Antineoplastic Agents; Azacitidine; Biomedical Research; Carbazoles; Carboplatin; Cytarabine; Daunorubicin; Decitabine; Enzyme Inhibitors; Etoposide; Flavonoids; Furans; Humans; Leukemia, Myeloid, Acute; Mitoxantrone; Piperidines; Quinolones; Staurosporine; Topotecan; Tretinoin

2008
The DNA Methyltransferase DNMT1 and Tyrosine-Protein Kinase KIT Cooperatively Promote Resistance to 5-Aza-2'-deoxycytidine (Decitabine) and Midostaurin (PKC412) in Lung Cancer Cells.
    The Journal of biological chemistry, 2015, Jul-24, Volume: 290, Issue:30

    Topics: Animals; Antigens, CD; Azacitidine; Cadherins; Cell Line, Tumor; Cell Proliferation; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Proto-Oncogene Proteins c-kit; Staurosporine

2015
Pancytopenia, eosinophilia and coagulation disorders in a patient with T-acute lymphoblastic leukemia in prolonged remission.
    American journal of hematology, 2021, 05-01, Volume: 96, Issue:5

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Biomarkers, Tumor; Blood Cell Count; Bone Marrow; Cancer Survivors; Chromosome Deletion; Chromosome Disorders; Chromosomes, Human, Pair 7; Diagnosis, Differential; Eosinophilia; Hemorrhagic Disorders; Humans; Interferon-alpha; Leukemia, Myeloid, Acute; Male; Mastocytosis, Systemic; Myelodysplastic Syndromes; Neoplasms, Second Primary; Pancytopenia; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Staurosporine; Tryptases

2021