Compounds > azacitidine

azacitidine and pyrimidin-2-one beta-ribofuranoside

azacitidine has been researched along with pyrimidin-2-one beta-ribofuranoside in 41 studies

Research

Studies (41)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (2.44)18.2507
2000's16 (39.02)29.6817
2010's21 (51.22)24.3611
2020's3 (7.32)2.80

Authors

AuthorsStudies
Laliberté, J; Marquez, VE; Momparler, RL1
Cheng, JC; Gonzales, FA; Hu, YG; Jones, PA; Liang, G; Marquez, VE; Weisenberger, DJ; Xu, GL1
Alleman, WG; Aprelikova, ON; Chandramouli, GV; Linehan, WM; Mendoza, A; Rodgers, C; Rogers, C; Sopko, NA; Tabios, RL; Torres-Cabala, C; Vasselli, JR1
Cheng, JC; Jones, PA; Yoo, CB1
Bernstein, ML; Lemaire, M; Marquez, VE; Momparler, LF; Momparler, RL1
Cherry, JC; Farrar, WL; Fox, SD; Hodge, DR; Hurt, EM; Kelley, JA; Munroe, DJ; Peng, B1
Balch, C; Craft, T; Huang, TH; Nephew, KP; Skalnik, DG; Yan, P; Young, S1
Chuang, JC; Jones, PA; Kwan, JM; Li, TW; Liang, G; Yang, AS; Yoo, CB1
Baylin, SB; Eguchi, S; Esteller, M; Fraga, MF; Fuks, F; Griffioen, AW; Hellebrekers, DM; Hoebers, NT; Jair, KW; van Engeland, M; Viré, E1
Brueckner, B; Lyko, F; Musch, T; Stopper, H; Stresemann, C1
Chen, Y; Costa, E; Grayson, DR; Kundakovic, M1
Christoph, F; Kempkensteffen, C; Köllermann, J; Krause, H; Miller, K; Schostak, M; Schrader, M; Weikert, S1
Berger, C; Bernasconi, M; Nadal, D; Rao, SP; Rechsteiner, MP; Sigrist, JA1
Bernstein, ML; Lemaire, M; Momparler, LF; Momparler, RL; Raynal, NJ1
Issa, JP1
Batz, C; Claus, R; Flotho, C; Ihde, S; Lübbert, M; Niemeyer, CM; Plass, C; Sandrock, I; Schneider, M1
Billam, M; Davidson, NE; Sobolewski, MD1
Betham, B; Bhagwat, AS; Marquez, VE; Shalhout, S1
Assaraf, YG; Bram, EE; Raz, S; Stark, M1
Chan, JY; Ho, WK; Man, OY; To, VS; Tsang, CM; Tsang, RK; Tsao, SW; Wei, WI; Wong, TS1
Arimondo, PB; Champion, C; Guianvarc'h, D; Guieysse-Peugeot, AL; Jeltsch, A; Jurkowska, RZ; Ponger, L; Sénamaud-Beaufort, C1
Farkas, DL; Gertych, A; Tajbakhsh, J1
Morales, JC; Rodríguez-Vargas, JM; Ruiz-Magaña, MJ; Ruiz-Ruiz, C; Saldivia, MA; Schulze-Osthoff, K1
Bianco-Miotto, T; Butler, LM; Centenera, MM; Chiam, K; Tilley, WD1
Barišić, D; Bosnar, MH; Horvat, T; Mužinić, A; Zoldoš, V1
Chie, EK; Kim, HJ; Kim, IA; Kim, IH; Kim, JH; Young, PD1
Haneef, K; Iqbal, H; Jamall, S; Kabir, N; Naeem, N; Salim, A1
Gertych, A; Oh, JH; Tajbakhsh, J; Wawrowsky, KA; Weisenberger, DJ1
Peng, M; Rothstein, SJ; Yaish, MW1
Flis, K; Flis, S; Gnyszka, A1
Arimany-Nardi, C; Errasti-Murugarren, E; Gorboulev, V; Koepsell, H; Martinez-Picado, J; Minuesa, G; Pastor-Anglada, M1
Campbell, RR; Dang, D; Ono, K; Schmidt, BL; Viet, CT; Ye, Y1
Levine, A; Sun, Y; Yi, L1
D'Souza, S; Kang, TM; Lam, K; Miller, JH; Song, LY; Yeh, P1
Griffin, PT; Niederhuth, CE; Schmitz, RJ1
Ang, J; D'Souza, S; Hong, IL; Luhar, R; Miller, JH; Song, LY; Yung, M1
Anglard, P; Befort, K; Filliol, D; Fonteneau, M; Romieu, P; Zwiller, J1
Butter, R; Linnekamp, JF; Medema, JP; Spijker, R; van Laarhoven, HWM1
Dvořák Tomaštíková, E; Ercan, U; Finke, A; Krečmerová, M; Niezgodzki, I; Nowicka, A; Otmar, M; Pecinka, A; Poppenberger, B; Procházková, K; Rozhon, W; Schubert, I; Tokarz, B; Zwyrtková, J1
Abd Elmageed, ZY; Ali, HEA; Buttolph, T; Carraway, HE; Cen, Y; Denvir, J; Fan, J; Fandy, TE; Malkaram, SA; Primerano, DA; Shatnawi, A1
Kabeer, SW; Kumar, V; Pal, D; Pant, R; Patra, D; Sharma, S; Tikoo, K1

Reviews

2 review(s) available for azacitidine and pyrimidin-2-one beta-ribofuranoside

ArticleYear
Zebularine: a new drug for epigenetic therapy.
    Biochemical Society transactions, 2004, Volume: 32, Issue:Pt 6

    Topics: Azacitidine; Cytidine; DNA Methylation; Epigenesis, Genetic; Genetic Therapy; Humans; Neoplasms; Pyrimidine Nucleosides

2004
Clinical and biological effects of demethylating agents on solid tumours - A systematic review.
    Cancer treatment reviews, 2017, Volume: 54

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Cytidine; Decitabine; DNA Methylation; Humans; Hydralazine; Immune System; Methylation; Neoplasms; Procaine; Treatment Outcome

2017

Other Studies

39 other study(ies) available for azacitidine and pyrimidin-2-one beta-ribofuranoside

ArticleYear
Potent inhibitors for the deamination of cytosine arabinoside and 5-aza-2'-deoxycytidine by human cytidine deaminase.
    Cancer chemotherapy and pharmacology, 1992, Volume: 30, Issue:1

    Topics: Antineoplastic Agents; Azacitidine; Azepines; Cytarabine; Cytidine; Cytidine Deaminase; Deamination; Decitabine; Humans; Kinetics; Pyrimidine Nucleosides; Tetrahydrouridine

1992
Continuous zebularine treatment effectively sustains demethylation in human bladder cancer cells.
    Molecular and cellular biology, 2004, Volume: 24, Issue:3

    Topics: Azacitidine; Cytidine; Decitabine; DNA; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Enzyme Inhibitors; Gene Silencing; Genes, p16; Humans; Pyrimidine Nucleosides; Urinary Bladder Neoplasms

2004
The in vitro and in vivo effects of re-expressing methylated von Hippel-Lindau tumor suppressor gene in clear cell renal carcinoma with 5-aza-2'-deoxycytidine.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Oct-15, Volume: 10, Issue:20

    Topics: Adenocarcinoma, Clear Cell; Animals; Antimetabolites, Antineoplastic; Azacitidine; Cytidine; Decitabine; Disease Models, Animal; DNA Methylation; Gene Silencing; Humans; Kidney Neoplasms; Mice; Pyrimidine Nucleosides; Reverse Transcriptase Polymerase Chain Reaction; Transfection; Transplantation, Heterologous; Tumor Cells, Cultured; Tumor Suppressor Proteins; Ubiquitin-Protein Ligases; Von Hippel-Lindau Tumor Suppressor Protein

2004
Enhancement of antineoplastic action of 5-aza-2'-deoxycytidine by zebularine on L1210 leukemia.
    Anti-cancer drugs, 2005, Volume: 16, Issue:3

    Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Cell Line, Tumor; Cytidine; Cytidine Deaminase; Decitabine; DNA Methylation; Dose-Response Relationship, Drug; Drug Interactions; Humans; Leukemia L1210; Male; Mice; Pyrimidine Nucleosides; Reverse Transcriptase Polymerase Chain Reaction; Tumor Stem Cell Assay

2005
Interleukin 6 supports the maintenance of p53 tumor suppressor gene promoter methylation.
    Cancer research, 2005, Jun-01, Volume: 65, Issue:11

    Topics: Apoptosis; Azacitidine; Base Sequence; Cell Cycle; Cell Line, Tumor; Cytidine; Decitabine; Deoxycytidine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Gene Silencing; Genes, p53; Humans; Interleukin-6; Molecular Sequence Data; Multiple Myeloma; Promoter Regions, Genetic; Sulfites; Tumor Suppressor Protein p53

2005
Antimitogenic and chemosensitizing effects of the methylation inhibitor zebularine in ovarian cancer.
    Molecular cancer therapeutics, 2005, Volume: 4, Issue:10

    Topics: Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cell Growth Processes; Cell Line, Tumor; Cisplatin; Cytidine; Decitabine; DNA Methylation; Drug Synergism; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Tumor Suppressor; Humans; Ovarian Neoplasms

2005
Comparison of biological effects of non-nucleoside DNA methylation inhibitors versus 5-aza-2'-deoxycytidine.
    Molecular cancer therapeutics, 2005, Volume: 4, Issue:10

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Carcinoma, Transitional Cell; Catechin; Cell Line, Tumor; Colorectal Neoplasms; Cytidine; Decitabine; Deoxycytidine; DNA Methylation; DNA Modification Methylases; Enzyme Inhibitors; Female; Gene Silencing; HT29 Cells; Humans; Hydralazine; Male; Procainamide; Prostatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction

2005
Angiostatic activity of DNA methyltransferase inhibitors.
    Molecular cancer therapeutics, 2006, Volume: 5, Issue:2

    Topics: Acetylation; Angiogenesis Inhibitors; Animals; Azacitidine; Cell Movement; Cytidine; DNA Modification Methylases; Endothelial Cells; Enzyme Inhibitors; Gene Expression; Histones; Humans; Hydroxamic Acids; Insulin-Like Growth Factor Binding Protein 3; Melanoma, Experimental; Mice; Mice, Mutant Strains; Neovascularization, Pathologic; Neovascularization, Physiologic; Thrombospondin 1

2006
Functional diversity of DNA methyltransferase inhibitors in human cancer cell lines.
    Cancer research, 2006, Mar-01, Volume: 66, Issue:5

    Topics: Azacitidine; Catechin; Cell Line, Tumor; Cytidine; Decitabine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Enzyme Inhibitors; Humans; Indoles; Jurkat Cells; Phthalimides; Procaine; Propionates; Tryptophan

2006
DNA methyltransferase inhibitors coordinately induce expression of the human reelin and glutamic acid decarboxylase 67 genes.
    Molecular pharmacology, 2007, Volume: 71, Issue:3

    Topics: Acetylation; Azacitidine; Cell Adhesion Molecules, Neuronal; Cells, Cultured; Cytidine; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; Dose-Response Relationship, Drug; Doxorubicin; Enzyme Inhibitors; Extracellular Matrix Proteins; Gene Expression Regulation; Glutamate Decarboxylase; Histones; Humans; Isoenzymes; Methyl-CpG-Binding Protein 2; Nerve Tissue Proteins; Reelin Protein; RNA, Messenger; Serine Endopeptidases

2007
Methylation of tumour suppressor genes APAF-1 and DAPK-1 and in vitro effects of demethylating agents in bladder and kidney cancer.
    British journal of cancer, 2006, Dec-18, Volume: 95, Issue:12

    Topics: Aged; Antimetabolites, Antineoplastic; Apoptosis Regulatory Proteins; Apoptotic Protease-Activating Factor 1; Azacitidine; Calcium-Calmodulin-Dependent Protein Kinases; Carcinoma, Renal Cell; Carcinoma, Transitional Cell; Cells, Cultured; Cytidine; Death-Associated Protein Kinases; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Humans; In Vitro Techniques; Kidney; Kidney Neoplasms; Male; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Urinary Bladder; Urinary Bladder Neoplasms

2006
Zebularine reactivates silenced E-cadherin but unlike 5-Azacytidine does not induce switching from latent to lytic Epstein-Barr virus infection in Burkitt's lymphoma Akata cells.
    Molecular cancer, 2007, Jan-10, Volume: 6

    Topics: Antineoplastic Agents; Azacitidine; Burkitt Lymphoma; Cadherins; Cytidine; Gene Silencing; Herpesvirus 4, Human; Humans; Tumor Cells, Cultured; Virus Latency

2007
Inhibition of cytidine deaminase by zebularine enhances the antineoplastic action of 5-aza-2'-deoxycytidine.
    Cancer chemotherapy and pharmacology, 2009, Volume: 63, Issue:3

    Topics: 3T3 Cells; Animals; Antineoplastic Agents; Azacitidine; Cytidine; Cytidine Deaminase; Decitabine; Drug Synergism; Enzyme Inhibitors; Leukemia, Experimental; Male; Mice; Mice, Inbred BALB C; Mice, Inbred DBA

2009
Cancer prevention: epigenetics steps up to the plate.
    Cancer prevention research (Philadelphia, Pa.), 2008, Volume: 1, Issue:4

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Cell Transformation, Neoplastic; Chemoprevention; Cytidine; Decitabine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Enzyme Inhibitors; Epigenesis, Genetic; Humans; Models, Biological; Neoplasms

2008
The DNA methyltransferase inhibitors azacitidine, decitabine and zebularine exert differential effects on cancer gene expression in acute myeloid leukemia cells.
    Leukemia, 2009, Volume: 23, Issue:6

    Topics: Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cytidine; Decitabine; DNA Methylation; DNA Modification Methylases; Enzyme Inhibitors; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Leukemia, Myeloid, Acute

2009
Effects of a novel DNA methyltransferase inhibitor zebularine on human breast cancer cells.
    Breast cancer research and treatment, 2010, Volume: 120, Issue:3

    Topics: Adenocarcinoma; Apoptosis Regulatory Proteins; Azacitidine; Breast Neoplasms; Cell Cycle Proteins; Cell Line, Tumor; Chromatin Immunoprecipitation; Cytidine; Cytidine Deaminase; Decitabine; DNA (Cytosine-5-)-Methyltransferases; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Drug Synergism; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Humans; Hydroxamic Acids; Neoplasm Proteins; Receptors, Estrogen; S Phase; Tumor Stem Cell Assay; Vorinostat

2010
Use of Drosophila deoxynucleoside kinase to study mechanism of toxicity and mutagenicity of deoxycytidine analogs in Escherichia coli.
    DNA repair, 2010, Feb-04, Volume: 9, Issue:2

    Topics: Animals; Antineoplastic Agents; Azacitidine; Cytidine; Deoxycytidine; DNA; DNA Methylation; DNA Mismatch Repair; Drosophila melanogaster; Escherichia coli; Fluorescence; Microbial Sensitivity Tests; Mutagenesis; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor)

2010
Chemotherapeutic drug-induced ABCG2 promoter demethylation as a novel mechanism of acquired multidrug resistance.
    Neoplasia (New York, N.Y.), 2009, Volume: 11, Issue:12

    Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Azacitidine; Cell Line, Tumor; Cell Proliferation; Cytidine; Decitabine; DNA Methylation; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Jurkat Cells; K562 Cells; Neoplasm Proteins; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction

2009
MicroRNA let-7 suppresses nasopharyngeal carcinoma cells proliferation through downregulating c-Myc expression.
    Journal of cancer research and clinical oncology, 2011, Volume: 137, Issue:3

    Topics: Azacitidine; Carcinoma; Cell Growth Processes; Cell Line, Tumor; Cytidine; DNA Methylation; Down-Regulation; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; MicroRNAs; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Proto-Oncogene Proteins c-myc; Transfection; Up-Regulation

2011
Mechanistic insights on the inhibition of c5 DNA methyltransferases by zebularine.
    PloS one, 2010, Aug-24, Volume: 5, Issue:8

    Topics: Animals; Azacitidine; Base Sequence; Cytidine; Decitabine; DNA; DNA (Cytosine-5-)-Methyltransferases; Enzyme Inhibitors; Humans; Methylation; Mice

2010
Measuring topology of low-intensity DNA methylation sites for high-throughput assessment of epigenetic drug-induced effects in cancer cells.
    Experimental cell research, 2010, Nov-15, Volume: 316, Issue:19

    Topics: Antineoplastic Agents; Azacitidine; Cell Line, Tumor; Cell Nucleus; Cytidine; Cytosine; DNA Methylation; DNA, Neoplasm; Epigenesis, Genetic; Fluorescence; High-Throughput Screening Assays; Humans; Indoles; Neoplasms; Nucleic Acid Conformation

2010
The DNA methyltransferase inhibitors zebularine and decitabine induce mitochondria-mediated apoptosis and DNA damage in p53 mutant leukemic T cells.
    International journal of cancer, 2012, Mar-01, Volume: 130, Issue:5

    Topics: Apoptosis; Azacitidine; Caspase 9; Cell Cycle; Cell Line, Tumor; Cytidine; Decitabine; DNA (Cytosine-5-)-Methyltransferases; DNA Damage; Genes, p53; Humans; Leukemia, T-Cell; Mitochondria; Mutation; Reactive Oxygen Species; T-Lymphocytes

2012
GSTP1 DNA methylation and expression status is indicative of 5-aza-2'-deoxycytidine efficacy in human prostate cancer cells.
    PloS one, 2011, Volume: 6, Issue:9

    Topics: Azacitidine; Biomarkers, Tumor; Cell Death; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cytidine; Decitabine; DNA Methylation; Dose-Response Relationship, Drug; Drug Discovery; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Gene Silencing; Glutathione S-Transferase pi; Humans; Male; Promoter Regions, Genetic; Prostate-Specific Antigen; Prostatic Neoplasms; Time Factors

2011
Epigenetic modulation of the HeLa cell membrane N-glycome.
    Biochimica et biophysica acta, 2012, Volume: 1820, Issue:9

    Topics: Antineoplastic Agents; Azacitidine; Butyrates; Carbohydrate Sequence; Cytidine; Decitabine; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Glycomics; HeLa Cells; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Molecular Sequence Data; Polysaccharides

2012
DNMT (DNA methyltransferase) inhibitors radiosensitize human cancer cells by suppressing DNA repair activity.
    Radiation oncology (London, England), 2012, Mar-20, Volume: 7

    Topics: Azacitidine; Caspase 3; Catechin; Cell Line, Tumor; Cytidine; Decitabine; Disulfides; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Breaks, Double-Stranded; DNA Methyltransferase 3A; DNA Methyltransferase 3B; DNA Repair; Enzyme Induction; Gene Expression Regulation, Neoplastic; Glioblastoma; Histones; Humans; Hydralazine; Inhibitory Concentration 50; Lung Neoplasms; Neoplasm Proteins; Radiation-Sensitizing Agents; Tumor Stem Cell Assay; Tyrosine

2012
DNA methylation inhibitors, 5-azacytidine and zebularine potentiate the transdifferentiation of rat bone marrow mesenchymal stem cells into cardiomyocytes.
    Cardiovascular therapeutics, 2013, Volume: 31, Issue:4

    Topics: Animals; Azacitidine; Bone Marrow Cells; Cell Fusion; Cell Transdifferentiation; Cells, Cultured; Coculture Techniques; Cytidine; DNA Methylation; DNA Modification Methylases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; GATA4 Transcription Factor; Gene Expression Regulation; Homeobox Protein Nkx-2.5; Homeodomain Proteins; Male; Mesenchymal Stem Cells; Myocytes, Cardiac; Rats; Rats, Sprague-Dawley; RNA, Messenger; Transcription Factors; Troponin T

2013
3-D DNA methylation phenotypes correlate with cytotoxicity levels in prostate and liver cancer cell models.
    BMC pharmacology & toxicology, 2013, Feb-11, Volume: 14

    Topics: 5-Methylcytosine; Antibodies, Monoclonal; Antineoplastic Agents; Apoptosis; Azacitidine; Cell Line, Tumor; Cell Survival; Cytidine; DNA Methylation; Humans; Liver Neoplasms; Male; Phenotype; Prostatic Neoplasms

2013
Global DNA methylation analysis using methyl-sensitive amplification polymorphism (MSAP).
    Methods in molecular biology (Clifton, N.J.), 2014, Volume: 1062

    Topics: Arabidopsis; Azacitidine; Base Sequence; Cytidine; Decitabine; DNA Methylation; DNA, Plant; Polymerase Chain Reaction; Polymorphism, Genetic; Seeds

2014
DNA methyltransferase inhibitors improve the effect of chemotherapeutic agents in SW48 and HT-29 colorectal cancer cells.
    PloS one, 2014, Volume: 9, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Azacitidine; Cell Cycle; Cell Line, Tumor; Colorectal Neoplasms; Cytidine; Decitabine; DNA Damage; DNA-Cytosine Methylases; Enzyme Inhibitors; Fluorouracil; Humans; Membrane Potential, Mitochondrial; Organoplatinum Compounds; Oxaliplatin

2014
Nucleoside transporters and human organic cation transporter 1 determine the cellular handling of DNA-methyltransferase inhibitors.
    British journal of pharmacology, 2014, Volume: 171, Issue:16

    Topics: Animals; Azacitidine; Biological Transport; Cell Survival; Cytidine; Decitabine; DNA Modification Methylases; Dogs; HeLa Cells; Humans; Madin Darby Canine Kidney Cells; Nucleoside Transport Proteins; Oocytes; Organic Cation Transporter 1; Xenopus laevis

2014
Demethylating drugs as novel analgesics for cancer pain.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2014, Sep-15, Volume: 20, Issue:18

    Topics: Analgesics, Opioid; Animals; Antineoplastic Agents; Azacitidine; Carcinoma, Squamous Cell; Cytidine; Decitabine; Disease Models, Animal; DNA Methylation; Heterografts; Humans; Immunohistochemistry; In Situ Hybridization; Mice; Mouth Neoplasms; Neurons; Pain; Receptors, Opioid, mu; Reverse Transcriptase Polymerase Chain Reaction; Transduction, Genetic; Trigeminal Ganglion

2014
Selected drugs that inhibit DNA methylation can preferentially kill p53 deficient cells.
    Oncotarget, 2014, Oct-15, Volume: 5, Issue:19

    Topics: Animals; Anticarcinogenic Agents; Azacitidine; Catechin; Cell Line, Tumor; Cell Proliferation; Cytidine; Decitabine; DNA Methylation; Humans; Lung Neoplasms; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutation; Neoplasm Transplantation; Phthalimides; Tryptophan; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays

2014
Exploring Synergy between Classic Mutagens and Antibiotics To Examine Mechanisms of Synergy and Antibiotic Action.
    Antimicrobial agents and chemotherapy, 2015, Dec-28, Volume: 60, Issue:3

    Topics: 2-Aminopurine; 4-Nitroquinoline-1-oxide; Anti-Bacterial Agents; Azacitidine; Bromodeoxyuridine; Chloramphenicol; Ciprofloxacin; Cytidine; DNA Breaks, Double-Stranded; Drug Synergism; Erythromycin; Escherichia coli; Gentamicins; Microbial Sensitivity Tests; Mutagens; Tetracycline; Trimethoprim; Vancomycin

2015
A Comparative Analysis of 5-Azacytidine- and Zebularine-Induced DNA Demethylation.
    G3 (Bethesda, Md.), 2016, 09-08, Volume: 6, Issue:9

    Topics: Arabidopsis; Azacitidine; Cytidine; DNA Methylation; Gene Expression Regulation, Plant; Gene Silencing; Transcriptome

2016
Mutagen Synergy: Hypermutability Generated by Specific Pairs of Base Analogs.
    Journal of bacteriology, 2016, 10-15, Volume: 198, Issue:20

    Topics: Azacitidine; Base Pairing; Bromodeoxyuridine; Cytidine; Drug Synergism; Escherichia coli; Escherichia coli Proteins; Mutagens; Mutation

2016
Inhibition of DNA methyltransferases regulates cocaine self-administration by rats: a genome-wide DNA methylation study.
    Genes, brain, and behavior, 2017, Volume: 16, Issue:3

    Topics: Animals; Azacitidine; Brain; Cocaine; Cocaine-Related Disorders; CpG Islands; Cytidine; Decitabine; DNA; DNA Methylation; DNA Modification Methylases; Enzyme Inhibitors; Epigenesis, Genetic; Genome; Male; Phosphatidylinositol 3-Kinases; Promoter Regions, Genetic; Rats; Rats, Wistar; Reinforcement, Psychology; Self Administration

2017
Comparative analysis of epigenetic inhibitors reveals different degrees of interference with transcriptional gene silencing and induction of DNA damage.
    The Plant journal : for cell and molecular biology, 2020, Volume: 102, Issue:1

    Topics: Adenosine; Arabidopsis; Azacitidine; Chromosome Aberrations; Cytidine; Decitabine; DNA Damage; DNA Methylation; DNA Repair; Epigenesis, Genetic; Gene Silencing; Heterochromatin; RNA Interference; Tandem Repeat Sequences

2020
Activation of SIRT6 by DNA hypomethylating agents and clinical consequences on combination therapy in leukemia.
    Scientific reports, 2020, 06-25, Volume: 10, Issue:1

    Topics: Acetylation; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Bone Marrow; Cell Line, Tumor; Cytidine; Decitabine; DNA Methylation; Histones; Humans; Leukemia, Myeloid, Acute; Sirtuins

2020
Pharmacological inhibition of DNMT1 restores macrophage autophagy and M2 polarization in Western diet-induced nonalcoholic fatty liver disease.
    The Journal of biological chemistry, 2023, Volume: 299, Issue:6

    Topics: Animals; Autophagy; Azacitidine; Cell Polarity; Diet, High-Fat; Diet, Western; DNA Methylation; Enzyme Inhibitors; Epigenesis, Genetic; Gene Knockdown Techniques; Liver; Macrophages; Mice; Non-alcoholic Fatty Liver Disease; RAW 264.7 Cells

2023