azacitidine and metallothionein

azacitidine has been researched along with metallothionein in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-199011 (42.31)18.7374
1990's7 (26.92)18.2507
2000's7 (26.92)29.6817
2010's1 (3.85)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Beitel, G; Foster, R; Gedamu, L; Jahroudi, N; Price-Haughey, J1
Angle, CR; Swanson, SA; Thomas, DJ1
Ho, T; Holliday, R1
Foster, R; Gedamu, L; Jahroudi, N1
Poirier, LA; Waalkes, MP1
Poirier, LA; Waalkes, MP; Wilson, MJ1
Crawford, BD; Hildebrand, CE; Stallings, RL; Tesmer, J; Tobey, RA1
Aono, K; Hashimoto, K; Hayashi, H; Kondoh, S; Shiraishi, N; Takeda, Y; Yamamoto, H1
Bonham, K; Gedamu, L; Price-Haughey, J1
Kuratomi, Y; Kuwano, M; Masumi, S; Ono, M; Yasutake, C1
Banks, GR; Gounari, F; Holliday, R; Jeggo, PA; Khazaie, K1
Lee, YH; Lin, JY; Lo, SJ; Pao, CC1
Bare, RM; McDowell, AE; Miller, MS; Waalkes, MP; Wilson, MJ1
Gedamu, L; Misra, S; Price-Haughey, J; Zafarullah, M1
Compere, SJ; Palmiter, RD1
Bahnson, RR; Lazo, JS; Reese, CE; Saijo, N; Woo, ES; Yang, YY1
Ghoshal, K; Jacob, ST; Li, Z; Majumder, S1
Bo, Y; Ghoshal, K; Jacob, ST; Li, Z; Majumder, S1
Bai, S; Datta, J; Dong, X; Ghoshal, K; Jacob, ST; Majumder, S; Plass, C; Quan, N1
Ghoshal, K; Jacob, ST; Majumder, S1
Bai, S; Datta, J; Dong, X; Ghoshal, K; Jacob, ST; Majumder, S; Parthun, M1
de la Chapelle, A; Huang, Y; Pellegata, NS1
Bisht, KS; Bradbury, CM; Brandenburg, SA; Chuang, EY; Cook, J; Cui, H; Feinberg, AP; Gius, D; Ho, AS; Hu, Y; Mattson, D; Mitchell, JB; Munson, PJ; Smart, DK; Sun, L; Young, L; Zhao, S1
Enomoto, S; Fujishiro, H; Himeno, S; Okugaki, S; Yasumitsu, S1
Ali, IY; Gupta, C; Gupta, J; Tikoo, K1
Nakagawa, H; Nobeyama, Y1

Other Studies

26 other study(ies) available for azacitidine and metallothionein

ArticleYear
Cell-type specific and differential regulation of the human metallothionein genes. Correlation with DNA methylation and chromatin structure.
    The Journal of biological chemistry, 1990, Apr-15, Volume: 265, Issue:11

    Topics: Azacitidine; Carcinoma, Hepatocellular; Cell Line; Chloramphenicol O-Acetyltransferase; Chromatin; DNA; Gene Expression Regulation; Genes; Humans; Kinetics; Liver Neoplasms; Metallothionein; Methylation; Organ Specificity; Plasmids; Promoter Regions, Genetic; Restriction Mapping; RNA, Messenger; Transcription, Genetic; Transfection; Tumor Cells, Cultured

1990
Effect of 5-azacytidine on metallothionein inducibility and sensitivity to lethality of cadmium in rat osteosarcoma (ROS 17/2.8) cells.
    Toxicology, 1990, Dec-17, Volume: 65, Issue:1-2

    Topics: Animals; Azacitidine; Cadmium; Chromatography, DEAE-Cellulose; Chromatography, Gel; Enzyme Induction; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Metallothionein; Osteosarcoma; Rats; Tumor Cells, Cultured

1990
Evidence for allelic exclusion in Chinese hamster ovary cells.
    The New biologist, 1990, Volume: 2, Issue:8

    Topics: Alleles; Animals; Azacitidine; Bromodeoxyuridine; Cell Line; Cricetinae; Cricetulus; Cytarabine; Diploidy; DNA; Drug Resistance; Female; Gene Expression; Herpesvirus 1, Equid; Metallothionein; Ovary; Thymidine Kinase; Transformation, Genetic

1990
5-Azacytidine increases the total cellular copper content and basal level metallothionein mRNA accumulation of human Hep G2 cells.
    Biochimica et biophysica acta, 1991, Mar-26, Volume: 1088, Issue:3

    Topics: Animals; Azacitidine; Blotting, Northern; Copper; Enzyme Induction; Gene Expression Regulation, Enzymologic; Humans; Liver Neoplasms, Experimental; Metallothionein; RNA, Messenger; Spectrophotometry, Atomic; Tumor Cells, Cultured

1991
Induction of hepatic metallothionein following 5-azacytidine administration.
    Toxicology and applied pharmacology, 1985, Jun-15, Volume: 79, Issue:1

    Topics: Animals; Azacitidine; Cells, Cultured; Chromatography, Gel; Chromatography, Ion Exchange; Dactinomycin; Female; Gene Expression Regulation; Liver; Male; Metallothionein; Rats; Rats, Inbred Strains; Spectrophotometry, Ultraviolet

1985
Reduced cadmium-induced cytotoxicity in cultured liver cells following 5-azacytidine pretreatment.
    Toxicology and applied pharmacology, 1985, Volume: 81, Issue:2

    Topics: Animals; Azacitidine; Cadmium; Cadmium Poisoning; DNA; Drug Interactions; In Vitro Techniques; Liver; Metallothionein; Potassium; Rats; Rats, Inbred F344; Thymidine; Tritium; Uridine

1985
5-Azacytidine-induced conversion to cadmium resistance correlates with early S phase replication of inactive metallothionein genes in synchronized CHO cells.
    Somatic cell and molecular genetics, 1986, Volume: 12, Issue:5

    Topics: Animals; Azacitidine; Cadmium; Cell Line; Cricetinae; Cricetulus; DNA; DNA Replication; Drug Resistance; Genes; Interphase; Metallothionein; Methylation

1986
Increased metallothionein content in rat liver and kidney following X-irradiation.
    Toxicology and applied pharmacology, 1986, Sep-15, Volume: 85, Issue:2

    Topics: Animals; Azacitidine; Bacterial Infections; Corticosterone; Dose-Response Relationship, Radiation; Kidney; Liver; Male; Metallothionein; Organ Size; Rats; Rats, Inbred Strains; Whole-Body Irradiation; Zinc

1986
Metallothionein gene expression in fish cell lines: its activation in embryonic cells by 5-azacytidine.
    Biochimica et biophysica acta, 1987, Feb-27, Volume: 908, Issue:2

    Topics: Animals; Azacitidine; Cadmium; Cell Line; Chemical Phenomena; Chemistry; Chromatography, Gel; Gene Expression Regulation; Metallothionein; Ovum; Protein Biosynthesis; RNA, Messenger; Salmon; Trout; Zinc

1987
Effect of 5-azacytidine on malignant transformation of a mutant derived from the mouse BALB/c 3T3 cell line resistant to transformation by chemical carcinogens.
    Cancer research, 1987, Sep-15, Volume: 47, Issue:18

    Topics: 4-Nitroquinoline-1-oxide; Animals; Azacitidine; Benzo(a)pyrene; Cell Line; Cell Transformation, Neoplastic; DNA; Epidermal Growth Factor; Metallothionein; Methylation; Methylnitronitrosoguanidine; Mice; Mice, Inbred BALB C; Mutation; Proto-Oncogenes; Tetradecanoylphorbol Acetate

1987
Gene reactivation: a tool for the isolation of mammalian DNA methylation mutants.
    Genes & development, 1987, Volume: 1, Issue:9

    Topics: Animals; Antineoplastic Agents; Azacitidine; Cell Line; Cricetinae; Cricetulus; Decitabine; DNA; Ethyl Methanesulfonate; Female; Genes; Metallothionein; Methylation; Mutation; Nucleic Acid Hybridization; Ovary; Temperature; Thymidine Kinase

1987
Enhanced production of hepatitis B virus surface antigen in mouse C127 cell on a bovine papillomavirus-metallothionein vector.
    Biochemistry international, 1988, Volume: 16, Issue:1

    Topics: Animals; Azacitidine; Cadmium; Cadmium Compounds; Cell Line; DNA, Recombinant; Genetic Vectors; Hepatitis B Surface Antigens; Metallothionein; Methylation; Mice; Papillomaviridae; Sulfates; Transfection

1988
Increased metallothionein gene expression in 5-aza-2'-deoxycytidine-induced resistance to cadmium cytotoxicity.
    Chemico-biological interactions, 1988, Volume: 66, Issue:3-4

    Topics: Animals; Azacitidine; Cadmium; Cell Line; Cell Survival; Decitabine; DNA; DNA Restriction Enzymes; Dose-Response Relationship, Drug; Drug Resistance; Gene Expression Regulation; Hydroxyurea; Kinetics; Liver; Metallothionein; Methylation; Nucleic Acid Hybridization; Rats; Rats, Inbred F344

1988
Analysis of stress-induced gene expression in fish cell lines exposed to heavy meals and heat shock.
    Biochimica et biophysica acta, 1989, Apr-12, Volume: 1007, Issue:3

    Topics: Animals; Azacitidine; Blotting, Northern; Cadmium; Cell Line; Fishes; Gene Expression Regulation; Heat-Shock Proteins; Hot Temperature; Metallothionein; Time Factors; Zinc

1989
DNA methylation controls the inducibility of the mouse metallothionein-I gene lymphoid cells.
    Cell, 1981, Volume: 25, Issue:1

    Topics: Animals; Azacitidine; Cadmium; Cell Line; Dexamethasone; DNA; Gene Expression Regulation; Metalloproteins; Metallothionein; Methylation; Mice; RNA, Messenger; Thymoma; Transcriptional Activation

1981
Human metallothionein isoform gene expression in cisplatin-sensitive and resistant cells.
    Molecular pharmacology, 1994, Volume: 45, Issue:3

    Topics: Azacitidine; Base Sequence; Cisplatin; Drug Resistance; Gene Expression; Humans; Metallothionein; Metals; Molecular Sequence Data; Restriction Mapping; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured

1994
Hypermethylation of metallothionein-I promoter and suppression of its induction in cell lines overexpressing the large subunit of Ku protein.
    The Journal of biological chemistry, 1999, Oct-01, Volume: 274, Issue:40

    Topics: Animals; Antigens, Nuclear; Azacitidine; Base Sequence; Cell Line; CpG Islands; DNA; DNA Footprinting; DNA Helicases; DNA Methylation; DNA-Binding Proteins; Gene Expression; Gene Silencing; Ku Autoantigen; Metallothionein; Molecular Sequence Data; Nuclear Proteins; Promoter Regions, Genetic; Rats

1999
Silencing of metallothionein-I gene in mouse lymphosarcoma cells by methylation.
    Oncogene, 1999, Nov-04, Volume: 18, Issue:46

    Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Base Sequence; CpG Islands; DNA Footprinting; DNA Methylation; DNA, Neoplasm; Gene Expression Regulation, Neoplastic; Gene Silencing; Lymphoma, Non-Hodgkin; Metallothionein; Metals, Heavy; Mice; Molecular Sequence Data; Neoplasm Proteins; Promoter Regions, Genetic; Regulatory Sequences, Nucleic Acid; Thymus Gland; Transcription Factors; Tumor Cells, Cultured

1999
Role of de novo DNA methyltransferases and methyl CpG-binding proteins in gene silencing in a rat hepatoma.
    The Journal of biological chemistry, 2002, May-03, Volume: 277, Issue:18

    Topics: Animals; Azacitidine; Base Sequence; Carrier Proteins; Cell Nucleus; Dinucleoside Phosphates; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA-Binding Proteins; DNA-Cytosine Methylases; Gene Expression Regulation, Neoplastic; Gene Silencing; Liver; Liver Neoplasms, Experimental; Metallothionein; Molecular Sequence Data; Promoter Regions, Genetic; Rats; Reverse Transcriptase Polymerase Chain Reaction; Substrate Specificity

2002
Analysis of promoter methylation and its role in silencing metallothionein I gene expression in tumor cells.
    Methods in enzymology, 2002, Volume: 353

    Topics: Animals; Azacitidine; Base Sequence; CpG Islands; DNA Methylation; Gene Expression Regulation, Neoplastic; Gene Silencing; Liver Neoplasms, Experimental; Metallothionein; Metals; Mice; Molecular Sequence Data; Polymerase Chain Reaction; Promoter Regions, Genetic; RNA, Messenger; Sarcoma; Sulfites; Tumor Cells, Cultured

2002
Inhibitors of histone deacetylase and DNA methyltransferase synergistically activate the methylated metallothionein I promoter by activating the transcription factor MTF-1 and forming an open chromatin structure.
    Molecular and cellular biology, 2002, Volume: 22, Issue:23

    Topics: Acetylation; Animals; Azacitidine; Base Sequence; Chromatin; Chromosomal Proteins, Non-Histone; DNA (Cytosine-5-)-Methyltransferases; DNA Footprinting; DNA-Binding Proteins; Enzyme Inhibitors; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Hydroxamic Acids; Metallothionein; Methyl-CpG-Binding Protein 2; Mice; Models, Genetic; Molecular Sequence Data; Promoter Regions, Genetic; Repressor Proteins; Sequence Analysis, DNA; Transcription Factor MTF-1; Transcription Factors; Tumor Cells, Cultured; Zinc

2002
Hypermethylation, but not LOH, is associated with the low expression of MT1G and CRABP1 in papillary thyroid carcinoma.
    International journal of cancer, 2003, May-10, Volume: 104, Issue:6

    Topics: Adenocarcinoma, Papillary; Adult; Aged; Azacitidine; Base Sequence; CpG Islands; DNA Methylation; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Tumor Suppressor; Humans; Hydroxamic Acids; Loss of Heterozygosity; Male; Metallothionein; Microsatellite Repeats; Middle Aged; Molecular Sequence Data; O(6)-Methylguanine-DNA Methyltransferase; Polymerase Chain Reaction; Promoter Regions, Genetic; Receptors, Retinoic Acid; Thyroid Neoplasms; Tumor Cells, Cultured

2003
Distinct effects on gene expression of chemical and genetic manipulation of the cancer epigenome revealed by a multimodality approach.
    Cancer cell, 2004, Volume: 6, Issue:4

    Topics: Algorithms; Apoptosis; Azacitidine; Cell Division; Cell Line, Tumor; Cluster Analysis; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3B; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Gene Silencing; Genome; Humans; Hydroxamic Acids; Metallothionein; Methyltransferases; Neoplasms; Oligonucleotide Array Sequence Analysis; Promoter Regions, Genetic; Reproducibility of Results; RNA, Messenger; Transcriptional Activation

2004
Involvement of DNA hypermethylation in down-regulation of the zinc transporter ZIP8 in cadmium-resistant metallothionein-null cells.
    Toxicology and applied pharmacology, 2009, Dec-01, Volume: 241, Issue:2

    Topics: Animals; Azacitidine; Cadmium; Cation Transport Proteins; Cells, Cultured; CpG Islands; Decitabine; DNA Methylation; DNA Modification Methylases; Epigenesis, Genetic; Gene Silencing; Metallothionein; Mice; Mice, Knockout; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger

2009
5-Azacytidine prevents cisplatin induced nephrotoxicity and potentiates anticancer activity of cisplatin by involving inhibition of metallothionein, pAKT and DNMT1 expression in chemical induced cancer rats.
    Toxicology letters, 2009, Dec-15, Volume: 191, Issue:2-3

    Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Azacitidine; Blood Urea Nitrogen; Blotting, Western; Breast Neoplasms; Cell Nucleus; Cisplatin; Colonic Neoplasms; Creatinine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; Drug Synergism; Drug Therapy, Combination; Female; Histones; Kidney Diseases; Male; Mammary Neoplasms, Experimental; Metallothionein; Neoplasms, Experimental; p38 Mitogen-Activated Protein Kinases; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley

2009
Silencing of metallothionein 1A gene in melanoma.
    Journal of dermatological science, 2017, Volume: 88, Issue:2

    Topics: 5' Untranslated Regions; Adolescent; Adult; Aged; Aged, 80 and over; Azacitidine; Cell Line, Tumor; Child; CpG Islands; Decitabine; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Male; Melanocytes; Melanoma; Metallothionein; Middle Aged; Nevus, Pigmented; Real-Time Polymerase Chain Reaction; Skin Neoplasms; Young Adult

2017