azacitidine and lde225

azacitidine has been researched along with lde225 in 4 studies

Research

Studies (4)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	3 (75.00)	24.3611
2020's	1 (25.00)	2.80

Authors

Authors	Studies
Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ	1
Mascarenhas, J	1
Al-Kali, A; Bhagavatula, K; Bogenberger, JM; Delman, DH; Foran, JM; Hansen, N; Mesa, RA; Mohan, J; Oliver, GR; Rakhshan, F; Tibes, R; Wood, T	1
Al-Kali, A; Bogenberger, J; Dueck, AC; Hashmi, S; Hogan, W; Kosiorek, HE; Litzow, MR; Mesa, R; Palmer, J; Sproat, L; Tibes, R	1

Reviews

1 review(s) available for azacitidine and lde225

Article	Year
Rationale for combination therapy in myelofibrosis. Best practice & research. Clinical haematology, 2014, Volume: 27, Issue:2 Topics: Antimetabolites, Antineoplastic; Azacitidine; Biphenyl Compounds; Clinical Trials as Topic; Decitabine; Drug Therapy, Combination; Gene Expression; Hematopoietic Stem Cells; Homeodomain Proteins; Humans; Hydroxamic Acids; Indoles; Janus Kinase 2; Mutation; Nitriles; Panobinostat; Primary Myelofibrosis; Protein Kinase Inhibitors; Pyrazoles; Pyridines; Pyrimidines; Recombinant Proteins; Serum Amyloid P-Component	2014

Article

Year

Rationale for combination therapy in myelofibrosis.

Best practice & research. Clinical haematology, 2014, Volume: 27, Issue:2

Topics: Antimetabolites, Antineoplastic; Azacitidine; Biphenyl Compounds; Clinical Trials as Topic; Decitabine; Drug Therapy, Combination; Gene Expression; Hematopoietic Stem Cells; Homeodomain Proteins; Humans; Hydroxamic Acids; Indoles; Janus Kinase 2; Mutation; Nitriles; Panobinostat; Primary Myelofibrosis; Protein Kinase Inhibitors; Pyrazoles; Pyridines; Pyrimidines; Recombinant Proteins; Serum Amyloid P-Component

2014

Trials

1 trial(s) available for azacitidine and lde225

Article	Year
Phase 1/1b study of azacitidine and hedgehog pathway inhibitor sonidegib in patients with myeloid neoplasms. Cancer, 2023, 08-01, Volume: 129, Issue:15 Topics: Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Hedgehog Proteins; Humans; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Chronic; Myelodysplastic Syndromes; Myeloproliferative Disorders; Treatment Outcome	2023

Other Studies

2 other study(ies) available for azacitidine and lde225

Article	Year
Identification of potent Yes1 kinase inhibitors using a library screening approach. Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15 Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship	2013
The Hedgehog pathway as targetable vulnerability with 5-azacytidine in myelodysplastic syndrome and acute myeloid leukemia. Journal of hematology & oncology, 2015, Oct-20, Volume: 8 Topics: Acute Disease; Aged; Aged, 80 and over; Anilides; Antimetabolites, Antineoplastic; Azacitidine; Biphenyl Compounds; Cell Line, Tumor; Cell Survival; Chromosomes, Human, Pair 5; Chromosomes, Human, Pair 7; Drug Synergism; Female; Hedgehog Proteins; High-Throughput Nucleotide Sequencing; HL-60 Cells; Humans; Leukemia, Myeloid; Male; Myelodysplastic Syndromes; Pyridines; RNA Interference; Signal Transduction	2015

Article

Year

Identification of potent Yes1 kinase inhibitors using a library screening approach.

Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15

Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship

2013

The Hedgehog pathway as targetable vulnerability with 5-azacytidine in myelodysplastic syndrome and acute myeloid leukemia.

Journal of hematology & oncology, 2015, Oct-20, Volume: 8

Topics: Acute Disease; Aged; Aged, 80 and over; Anilides; Antimetabolites, Antineoplastic; Azacitidine; Biphenyl Compounds; Cell Line, Tumor; Cell Survival; Chromosomes, Human, Pair 5; Chromosomes, Human, Pair 7; Drug Synergism; Female; Hedgehog Proteins; High-Throughput Nucleotide Sequencing; HL-60 Cells; Humans; Leukemia, Myeloid; Male; Myelodysplastic Syndromes; Pyridines; RNA Interference; Signal Transduction

2015