azacitidine and hydroxyurea

azacitidine has been researched along with hydroxyurea in 108 studies

Research

Studies (108)

TimeframeStudies, this research(%)All Research%
pre-199038 (35.19)18.7374
1990's19 (17.59)18.2507
2000's28 (25.93)29.6817
2010's18 (16.67)24.3611
2020's5 (4.63)2.80

Authors

AuthorsStudies
Hansch, C; Khwaja, TA; Selassie, CD1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Lombardo, F; Obach, RS; Waters, NJ1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Bonnac, L; Clouser, CL; Daly, MB; Kim, B; Landman, SR; Mansky, LM; Patterson, SE; Rawson, JM; Reilly, CS; Roth, ME; Xie, J1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Borsos, T; Ohanian, SH; Segerling, M1
Cihak, A1
Alexander, B; Berger, R; Cook, WD; Day, LM; Feneziani, A; Hogarth, PM1
Ranney, HM1
Nienhuis, AW; Stamatoyannopoulos, JA1
Prasanna, P; Samid, D; Yeh, A1
Hudson, JL; Liebling, MR; Richardson, BC1
Charache, S4
Constantoulakis, P; Costantini, F; Enver, T; Josephson, B; Mangahas, L; Papayannopoulou, T; Stamatoyannopoulos, G1
Boswell, VD; Datta, MC; Dowla, HA; Srivastava, KK; Washington, I1
Constantoulakis, P; Costantini, F; Fry, D; Josephson, B; Mangahas, L; Stamatoyannopoulos, G1
Beardsley, GP; Letvin, NL; Linch, DC; McIntyre, KW; Miller, BA; Nathan, DG1
Galanello, R; Papayannopoulou, T; Stamatoyannopoulos, G; Veith, R2
Dover, G; Humphries, RK; Ley, TJ; Nienhuis, AW; Young, NS1
Boyer, SH; Charache, S; Dover, GJ; Nora, R1
Dean, A; Fordis, CM; Ley, T; Schechter, AN; Wu, YJ1
Boyer, S; Charache, S; Dover, GJ; Humphries, RK; Ley, T; Nienhuis, A; Young, N1
Hanotte, O; Menozzi, FD; Miller, AO1
Platt, OS2
Depper, JM; Greene, WC; Leonard, WJ1
Charache, S; Dover, GJ; Humphries, RK; Ley, TJ; Moore, JG; Nienhuis, AW; Young, NS1
DeSimone, J; Hall, L; Heller, P; Lavelle, D; Zwiers, D1
Estey, E; Silberman, L; Zwelling, LA1
Frahm, J; Hoshino, J; Kröger, H1
Frost, P; Hunt, B; Kerbel, RS; Man, S; Pathak, S1
Charache, S; Dover, GJ3
Dover, G; Hope, S; Miller, BA; Nathan, DG; Platt, O1
Noguchi, CT; Rodgers, GP; Schechter, AN; Serjeant, G1
Galanello, R; Papayannopoulou, T; Stamatoyannopoulos, G1
Alvarez, E; Elliott, BE; Houghton, AN; Kerbel, RS1
Alter, BP1
Bare, RM; McDowell, AE; Miller, MS; Waalkes, MP; Wilson, MJ1
Pfeifer, GP; Steigerwald, SD1
Cano, C; Herrera-Estrella, L; Ruiz-Herrera, J1
Ley, TJ; Nienhuis, AW1
Benedict, WF; Karon, M1
Burchenal, JH; Carter, SK1
Detke, S1
Boyer, SH; Charache, S; Dover, GJ1
Kessel, D; Khilanani, P; Lomen, PL1
DeSimone, J; Hall, L; Heller, P; Zwiers, D1
Kolata, G1
Beardsley, GP; Letvin, NL; Linch, DC; McIntyre, KW; Nathan, DG1
Adamson, JW1
Craig, JE; Rochette, J; Thein, SL1
DeSimone, J; Heller, P; Lavelle, D1
Fibach, E; Prasanna, P; Rodgers, GP; Samid, D1
Olivieri, NF1
Pearson, HA1
Li, J; Noguchi, CT; Schechter, AN; Smith, RD1
Bressler, L; DeSimone, J; Dorn, L; Hoffman, R; Koshy, M; Lavelle, D; Molokie, R; Talischy, N; van Overveld, W1
Atweh, GF; Schechter, AN1
Rodgers, GP; Saunthararajah, Y1
Matsuo, T; Tomonaga, M1
Datta, S1
Erdlenbruch, B; Kanbach, K; Monkemeyer, S; Pekrun, A; Reinhardt, D; Rönndahl, G; Witt, O1
Steinberg, MH2
Böhmer, RM1
Adams, RJ; Atweh, GF; DeSimone, J; Fabry, ME; Fathallah, H; Nagel, RL; Saunthararajah, Y; Weinberg, RS1
Cao, H1
DeSimone, J1
Atweh, GF; Fathallah, H; Sutton, M1
Aliyu, ZY; Kato, GJ; Tumblin, AR1
Bouabdallah, K; Daskalakis, M; Johansson, B; Kunzmann, R; Lübbert, M; Mauritzson, N; Müller-Berndorff, H; Onida, F; Schmitt-Gräff, A1
Dover, GJ; Keefer, JR; Mays, A; Purvis, SH; Schneidereith, TA; Smith, KD1
Hatzimichael, EC; Makis, AC; Stebbing, J1
Atweh, GF; Fathallah, H1
Byun, HM; Choi, SH; Issa, JP; Kwan, JM; Yang, AS1
Grosveld, FG; Patrinos, GP1
Alkan, S; Barton, K; Germano, E; Godwin, J; Michaelis, L; Nand, S; Rychlik, K; Smith, S; Stiff, P; Veerappan, R1
Roberts, I; Trompeter, S1
Fathallah, H1
Cappellini, MD; Musallam, KM; Sankaran, VG; Taher, AT1
Breda, L; Gambari, R; Rivella, S; Zuccato, C1
Appelbaum, FR; Coutre, SE; Erba, HP; Godwin, JE; Howard, DS; Nand, S; Norwood, TH; Othus, M; Willman, CL1
Prada Garcia, C; Rodriguez Prieto, MÁ; Sanchez Sambucety, P1
Schlenk, RF; Thol, F1
Brun, G; Delavault, P; Lechat, MM; Montiel, G; Pouvreau, JB; Simier, P; Thoiron, S; Véronési, C1
DeSimone, J; Ibanez, V; Lavelle, D; Mahmud, N; Rivers, A; Ruiz, MA; Vaitkus, K1
Achille, NJ; Appelbaum, FR; Cooper, K; Erba, HP; Godwin, JE; Nand, S; Othus, M; Phelan, K; Radich, JP; Zeleznik-Le, NJ; Zhang, S1
Balleari, E; Bernal, T; Beyne-Rauzy, O; Bordessoule, D; Calabuig, M; Cametti, G; Campelo, MD; Cheze, S; Cony-Makhoul, P; Dreyfus, F; Fenaux, P; Fensterl, J; Ferrero, D; Gaidano, G; Germing, U; Gioia, D; Götze, K; Guerci-Bresler, A; Hamel, JF; Kaivers, J; Kelaidi, C; Komrokji, R; Kotsianidis, I; Müller-Thomas, C; Pane, F; Park, S; Ramos, F; Roboz, GJ; Rose, C; Sanna, A; Santini, V; Sanz, GF; Sapena, R; Sekeres, MA; Stamatoullas, A; Steensma, DP; Thépot, S; Toma, A; Vey, N; Wattel, E1
Ades, L; Bally, C; Bergeron, A; Burns, R; Fenaux, P; Hilmi, M; Lorillon, G1
Burgstaller, S; Egle, A; Faber, V; Geissler, K; Greil, R; Huemer, F; Lang, A; Machherndl-Spandl, S; Neureiter, D; Pfeilstöcker, M; Pichler, A; Pleyer, L; Sperr, W; Stampfl, M; Stauder, R; Voskova, D; Weiss, L; Zebisch, A1
Curtis, SA; Folkers, A; Medoff, E; Mixon, R; Shallis, RM; Xu, ML; Zeidan, AM1
Anaclerico, B; Andriani, A; Aroldi, A; Breccia, M; Carmosino, I; Centra, A; Di Veroli, A; Elli, E; Fianchi, L; Foà, R; Latagliata, R; Martini, V; Montanaro, G; Montanaro, M; Niscola, P; Trapè, G; Villivà, N; Voso, MT1
Antunovic, P; Cammenga, J; Deneberg, S; Derolf, ÅR; Eriksson, A; Höglund, M; Juliusson, G; Lazarevic, V; Lehmann, S; Lorenz, F; Möllgård, L; Ölander, E; Österroos, A; Uggla, B; Wennström, L1
Fu, L; Hu, L; Hu, M; Zheng, B1
Arnan, M; Avendaño Pita, A; Bernal Del Castillo, T; Bonadies, N; Calabuig Muñoz, M; Cermak, J; Cortés, A; Dimou, M; Egle, A; Galanopoulos, A; Geissler, K; Germing, U; Greil, R; Heibl, S; Hellstroem-Lindberg, E; Hunter, AM; Jerez, A; Jimenez Lorenzo, MJ; Kaivers, J; Kourakli, A; Larcher-Senn, J; Leisch, M; List, AF; Lopez Andrade, B; Maciejewski, JP; Medina de Almeida, A; Melchardt, T; Montoro, MJ; Mora, E; Padron, E; Patel, BJ; Patiou, P; Pleyer, L; Roubakis, C; Sanz, GF; Sekeres, MA; Symeonidis, A; Ungerstedt, J; Valent, P; Viniou, AN; Xicoy Cirici, B1
Geissler, K; Reiser, J1

Reviews

35 review(s) available for azacitidine and hydroxyurea

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
The spectrum of sickle cell disease.
    Hospital practice (Office ed.), 1992, Jan-15, Volume: 27, Issue:1

    Topics: Adolescent; Adult; Anemia, Sickle Cell; Azacitidine; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 16; Female; Fluid Therapy; Genotype; Globins; Hemoglobin, Sickle; Humans; Hydroxyurea; Male; Oxygen Inhalation Therapy; Polymorphism, Genetic; Pregnancy

1992
Therapeutic approaches to hemoglobin switching in treatment of hemoglobinopathies.
    Annual review of medicine, 1992, Volume: 43

    Topics: Anemia, Sickle Cell; Animals; Azacitidine; Erythropoietin; Fetal Hemoglobin; Gene Expression Regulation; Hemoglobinopathies; Humans; Hydroxyurea; Thalassemia

1992
Fetal hemoglobin, sickling, and sickle cell disease.
    Advances in pediatrics, 1990, Volume: 37

    Topics: Adolescent; Adult; Anemia, Sickle Cell; Animals; Azacitidine; Child; Fetal Hemoglobin; Humans; Hydroxyurea; Infant, Newborn; Papio; Sheep

1990
Hydroxyurea as treatment for sickle cell anemia.
    Hematology/oncology clinics of North America, 1991, Volume: 5, Issue:3

    Topics: Anemia, Sickle Cell; Animals; Azacitidine; Erythropoietin; Humans; Hydroxyurea

1991
Augmentation of hemoglobin synthesis by S-phase specific drugs in the K562 cell line.
    Progress in clinical and biological research, 1985, Volume: 191

    Topics: Adult; Azacitidine; Cell Line; Cytarabine; Deoxyribonuclease HpaII; DNA Restriction Enzymes; Fetal Hemoglobin; Globins; Hemoglobinopathies; Humans; Hydroxyurea; Interphase; Kinetics; Transcription, Genetic

1985
Pharmacologic stimulation of Hb F in patients with sickle cell anemia.
    Progress in clinical and biological research, 1985, Volume: 191

    Topics: Anemia, Sickle Cell; Azacitidine; Cell Survival; Erythropoiesis; Fetal Hemoglobin; Homozygote; Humans; Hydroxyurea; Kinetics; Reticulocytes; Stem Cells

1985
Growth of human T lymphocytes: an analysis of interleukin 2 and its cellular receptor.
    Progress in hematology, 1986, Volume: 14

    Topics: Animals; Antibodies, Monoclonal; Antigens, Surface; Azacitidine; B-Lymphocytes; Cell Differentiation; Cell Division; Cells, Cultured; Cloning, Molecular; Deltaretrovirus; DNA; Gene Expression Regulation; Humans; Hydroxyurea; Interleukin-2; Leukemia, Lymphoid; Lymphocyte Activation; Mice; Phorbol Esters; Pokeweed Mitogens; Primates; Rats; Receptors, Immunologic; Receptors, Interleukin-2; Retroviridae Infections; RNA Processing, Post-Transcriptional; RNA, Messenger; T-Lymphocytes; Tumor Necrosis Factor Receptor Superfamily, Member 7

1986
Intercalator-induced, topoisomerase II-mediated DNA cleavage and its modification by antineoplastic antimetabolites.
    International journal of radiation oncology, biology, physics, 1986, Volume: 12, Issue:7

    Topics: Aminoacridines; Amsacrine; Animals; Antineoplastic Agents; Azacitidine; Cell Survival; Cytarabine; DNA; DNA Topoisomerases, Type II; Drug Synergism; Humans; Hydroxyurea; In Vitro Techniques; Intercalating Agents; Mice

1986
Levels of fetal hemoglobin necessary for treatment of sickle cell disease.
    The New England journal of medicine, 1988, Jan-14, Volume: 318, Issue:2

    Topics: Anemia, Sickle Cell; Azacitidine; Fetal Hemoglobin; Humans; Hydroxyurea; Polymers

1988
Hemoglobin F switching.
    Birth defects original article series, 1988, Volume: 23, Issue:5B

    Topics: Animals; Azacitidine; Bone Marrow Examination; Fetal Hemoglobin; Humans; Hydroxyurea

1988
Chemotherapy and hemoglobin F synthesis in sickle cell disease.
    Annals of the New York Academy of Sciences, 1989, Volume: 565

    Topics: Anemia, Sickle Cell; Animals; Azacitidine; Clinical Trials as Topic; Erythropoietin; Fetal Hemoglobin; Humans; Hydroxyurea; Interleukin-3; Papio; Recombinant Proteins

1989
Induction of hemoglobin F synthesis in patients with beta thalassemia.
    Annual review of medicine, 1985, Volume: 36

    Topics: Animals; Azacitidine; DNA; Erythroblasts; Female; Fetal Hemoglobin; Gene Expression Regulation; Globins; Humans; Hydroxyurea; Methylation; Papio; Thalassemia

1985
New cancer chemotherapeutic agents.
    Cancer, 1972, Volume: 30, Issue:6

    Topics: Aldehydes; Amides; Amines; Animals; Antineoplastic Agents; Asparaginase; Azacitidine; Azaguanine; Bleomycin; Carmustine; Chlorides; Cyclization; Cyclohexanes; Cytarabine; Cytidine; Doxorubicin; Glycosides; Humans; Hydroxyurea; Imidazoles; Leukemia, Lymphoid; Leukemia, Myeloid; Mice; Nitrosourea Compounds; Picolinic Acids; Platinum; Podophyllotoxin; Streptozocin; Thiosemicarbazones; Triazenes

1972
Fetal hemoglobin levels in adults.
    Blood reviews, 1994, Volume: 8, Issue:4

    Topics: Adult; Azacitidine; Base Sequence; Butyrates; Butyric Acid; Fetal Hemoglobin; Gene Expression Regulation; Genetic Therapy; Globins; Humans; Hydroxyurea; Molecular Sequence Data; Sequence Deletion; Thalassemia

1994
Fetal hemoglobin reactivation in baboon and man: a short perspective.
    American journal of hematology, 1993, Volume: 42, Issue:1

    Topics: Anemia, Sickle Cell; Animals; Azacitidine; Butyrates; Butyric Acid; Erythropoietin; Fetal Hemoglobin; Humans; Hydroxyurea; Papio

1993
Pharmacological modification of hemoglobin F expression in sickle cell anemia: an update on hydroxyurea studies.
    Experientia, 1993, Feb-15, Volume: 49, Issue:2

    Topics: Anemia, Sickle Cell; Animals; Azacitidine; Erythrocytes; Fetal Hemoglobin; Gene Expression; Humans; Hydroxyurea

1993
Reactivation of fetal hemoglobin in patients with beta-thalassemia.
    Seminars in hematology, 1996, Volume: 33, Issue:1

    Topics: Azacitidine; beta-Thalassemia; Butyrates; Butyric Acid; Erythropoietin; Fetal Hemoglobin; Homozygote; Humans; Hydroxyurea; Treatment Outcome

1996
Pharmacologic manipulation of fetal hemoglobin levels in sickle cell diseases and thalassemia: promise and reality.
    Advances in pediatrics, 1996, Volume: 43

    Topics: Anemia, Sickle Cell; Antineoplastic Agents; Antisickling Agents; Azacitidine; beta-Thalassemia; Erythropoietin; Fetal Hemoglobin; Humans; Hydroxyurea; Phenylbutyrates

1996
Pharmacologic induction of fetal hemoglobin: raising the therapeutic bar in sickle cell disease.
    Current opinion in hematology, 2001, Volume: 8, Issue:2

    Topics: Anemia, Sickle Cell; Azacitidine; Butyrates; Decitabine; Fetal Hemoglobin; Humans; Hydroxyurea

2001
Advances in experimental treatment of beta-thalassaemia.
    Expert opinion on investigational drugs, 2001, Volume: 10, Issue:5

    Topics: Azacitidine; beta-Thalassemia; Drug Therapy, Combination; Erythropoietin; Histone Deacetylase Inhibitors; Humans; Hydroxyurea; Iron Chelating Agents

2001
[Chemotherapy and radiation therapy].
    Nihon rinsho. Japanese journal of clinical medicine, 2001, Volume: 59, Issue:12

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Azacitidine; Busulfan; Decitabine; Harringtonines; Homoharringtonine; Humans; Hydroxyurea; Leukemia, Myeloid, Chronic-Phase

2001
Therapies to increase fetal hemoglobin in sickle cell disease.
    Current hematology reports, 2003, Volume: 2, Issue:2

    Topics: Anemia, Sickle Cell; Azacitidine; Butyrates; Cytokines; Decitabine; Drug Therapy, Combination; Fetal Hemoglobin; Humans; Hydroxyurea

2003
Hemoglobinopathies.
    Hematology. American Society of Hematology. Education Program, 2003

    Topics: Animals; Azacitidine; Butyrates; Cerebral Hemorrhage; Decitabine; Disease Models, Animal; DNA Methylation; Globins; Hemoglobinopathies; Humans; Hydroxyurea; Mice; Stroke

2003
Pharmacological induction of fetal hemoglobin synthesis using histone deacetylase inhibitors.
    Hematology (Amsterdam, Netherlands), 2004, Volume: 9, Issue:3

    Topics: Anemia, Sickle Cell; Azacitidine; beta-Thalassemia; Enzyme Inhibitors; Fetal Hemoglobin; Histone Deacetylase Inhibitors; Humans; Hydroxyurea

2004
Pharmacological induction of fetal hemoglobin: Why haven't we been more successful in thalassemia?
    Annals of the New York Academy of Sciences, 2005, Volume: 1054

    Topics: Anemia, Sickle Cell; Animals; Azacitidine; Combined Modality Therapy; Drug Approval; Drug Evaluation; Drug Evaluation, Preclinical; Erythropoiesis; Fetal Hemoglobin; Gene Expression; Gene Expression Regulation; Globins; Humans; Hydroxyurea; Iron; K562 Cells; Models, Animal; Papio; Thalassemia; Transfusion Reaction; United States; United States Food and Drug Administration

2005
Pathophysiologically based drug treatment of sickle cell disease.
    Trends in pharmacological sciences, 2006, Volume: 27, Issue:4

    Topics: Anemia, Sickle Cell; Animals; Anti-Inflammatory Agents; Antisickling Agents; Azacitidine; Cell Adhesion; Drug Therapy, Combination; Endothelium, Vascular; Erythrocytes; Fetal Hemoglobin; Gene Expression Regulation; Hemoglobin, Sickle; Humans; Hydroxyurea; K Cl- Cotransporters; Pyrrolidonecarboxylic Acid; Randomized Controlled Trials as Topic; Symporters

2006
The genomics of new drugs in sickle cell disease.
    Pharmacogenomics, 2006, Volume: 7, Issue:6

    Topics: Anemia, Sickle Cell; Antisickling Agents; Azacitidine; Butyrates; Decitabine; Drug Resistance; Humans; Hydroxyurea; Nitric Oxide; Pharmacogenetics; Phenotype; Poloxamer; Polymorphism, Genetic; Sulfasalazine; Toxicogenetics

2006
Induction of fetal hemoglobin in the treatment of sickle cell disease.
    Hematology. American Society of Hematology. Education Program, 2006

    Topics: Anemia, Sickle Cell; Azacitidine; Butyrates; Decitabine; Fetal Hemoglobin; Gene Expression Regulation; Humans; Hydroxyurea

2006
Pharmacogenomics and therapeutics of hemoglobinopathies.
    Hemoglobin, 2008, Volume: 32, Issue:1-2

    Topics: Azacitidine; Butyrates; Decitabine; Fetal Hemoglobin; Genome, Human; Hemoglobinopathies; Humans; Hydroxyurea; Pharmacogenetics; Polymorphism, Single Nucleotide

2008
Haemoglobin F modulation in childhood sickle cell disease.
    British journal of haematology, 2009, Volume: 144, Issue:3

    Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Azacitidine; Butyrates; Child; Clinical Trials as Topic; Decitabine; Fetal Hemoglobin; Humans; Hydroxyurea; Stroke; Young Adult

2009
Clinical experience with fetal hemoglobin induction therapy in patients with β-thalassemia.
    Blood, 2013, Mar-21, Volume: 121, Issue:12

    Topics: Anemia, Sickle Cell; Antisickling Agents; Azacitidine; beta-Thalassemia; DNA Methylation; Fetal Hemoglobin; Humans; Hydroxyurea; Professional Practice; Treatment Outcome; Up-Regulation

2013
Gemtuzumab ozogamicin in acute myeloid leukemia revisited.
    Expert opinion on biological therapy, 2014, Volume: 14, Issue:8

    Topics: Age Factors; Aminoglycosides; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Gemtuzumab; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Recurrence; Treatment Failure

2014
Conviction in the face of affliction: a case series of Jehovah's Witnesses with myeloid malignancies.
    Annals of hematology, 2018, Volume: 97, Issue:11

    Topics: Aged; Anemia, Macrocytic; Antimetabolites, Antineoplastic; Arthritis, Rheumatoid; Azacitidine; Blood Transfusion; Breast Neoplasms; Female; Humans; Hydroxyurea; Isocitrate Dehydrogenase; Jehovah's Witnesses; Leukemia, Myeloid, Acute; Male; Myeloproliferative Disorders; Neoplasms, Second Primary; Treatment Refusal

2018
Chronic myelomonocytic leukemia (CMML)-0 with pleural effusion as first manifestation: A case report.
    Medicine, 2020, Oct-30, Volume: 99, Issue:44

    Topics: Adult; Antineoplastic Agents; Azacitidine; Diagnosis, Differential; Drug Therapy, Combination; Female; Humans; Hydroxyurea; Leukemia, Myelomonocytic, Chronic; Lung Neoplasms; Pleural Effusion; Tomography, X-Ray Computed

2020

Trials

9 trial(s) available for azacitidine and hydroxyurea

ArticleYear
Hydroxyurea as treatment for sickle cell anemia.
    Hematology/oncology clinics of North America, 1991, Volume: 5, Issue:3

    Topics: Anemia, Sickle Cell; Animals; Azacitidine; Erythropoietin; Humans; Hydroxyurea

1991
Progress toward increasing fetal hemoglobin production in man: experience with 5-azacytidine and hydroxyurea.
    Annals of the New York Academy of Sciences, 1985, Volume: 445

    Topics: Anemia, Sickle Cell; Animals; Azacitidine; Bone Marrow; Cells, Cultured; Clinical Trials as Topic; Erythropoiesis; Fetal Hemoglobin; Humans; Hydroxyurea; Reticulocytes; Thalassemia

1985
Chemotherapy and hemoglobin F synthesis in sickle cell disease.
    Annals of the New York Academy of Sciences, 1989, Volume: 565

    Topics: Anemia, Sickle Cell; Animals; Azacitidine; Clinical Trials as Topic; Erythropoietin; Fetal Hemoglobin; Humans; Hydroxyurea; Interleukin-3; Papio; Recombinant Proteins

1989
Phase I study using combination of hydroxyurea and 5-azacytidine (NSC-102816).
    Neoplasma, 1980, Volume: 27, Issue:1

    Topics: Adult; Aged; Azacitidine; Bone Marrow; Clinical Trials as Topic; Drug Therapy, Combination; Humans; Hydroxyurea; Leukemia; Middle Aged; Neoplasms; Time Factors

1980
Experimental therapy of sickle cell disease. Use of hydroxyurea.
    The American journal of pediatric hematology/oncology, 1994, Volume: 16, Issue:1

    Topics: Anemia, Sickle Cell; Azacitidine; Bone Marrow Transplantation; Humans; Hydroxyurea

1994
Pharmacological modification of hemoglobin F expression in sickle cell anemia: an update on hydroxyurea studies.
    Experientia, 1993, Feb-15, Volume: 49, Issue:2

    Topics: Anemia, Sickle Cell; Animals; Azacitidine; Erythrocytes; Fetal Hemoglobin; Gene Expression; Humans; Hydroxyurea

1993
Hydroxyurea, azacitidine and gemtuzumab ozogamicin therapy in patients with previously untreated non-M3 acute myeloid leukemia and high-risk myelodysplastic syndromes in the elderly: results from a pilot trial.
    Leukemia & lymphoma, 2008, Volume: 49, Issue:11

    Topics: Aged; Aged, 80 and over; Aminoglycosides; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Drug-Related Side Effects and Adverse Reactions; Gemtuzumab; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Middle Aged; Myelodysplastic Syndromes; Pilot Projects; Remission Induction; Risk Assessment; Survival Analysis

2008
A phase 2 trial of azacitidine and gemtuzumab ozogamicin therapy in older patients with acute myeloid leukemia.
    Blood, 2013, Nov-14, Volume: 122, Issue:20

    Topics: Age Factors; Aged; Aged, 80 and over; Aminoglycosides; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Disease-Free Survival; Female; Gemtuzumab; Humans; Hydroxyurea; Kaplan-Meier Estimate; Karnofsky Performance Status; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Male; Middle Aged; Risk; Survival Analysis

2013
Association between early promoter-specific DNA methylation changes and outcome in older acute myeloid leukemia patients.
    Leukemia research, 2016, Volume: 42

    Topics: Aged; Aminoglycosides; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; DNA Methylation; Enzyme-Linked Immunosorbent Assay; Female; Gemtuzumab; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis; Promoter Regions, Genetic; Real-Time Polymerase Chain Reaction; Risk Factors; Transcriptome; Treatment Outcome

2016

Other Studies

67 other study(ies) available for azacitidine and hydroxyurea

ArticleYear
Structure-activity relationships of antineoplastic agents in multidrug resistance.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:7

    Topics: Animals; Antineoplastic Agents; Cell Line; Cell Survival; Cricetinae; Dactinomycin; Drug Resistance; Leukemia L1210; Mice; Regression Analysis; Structure-Activity Relationship; Tumor Cells, Cultured

1990
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Synergistic reduction of HIV-1 infectivity by 5-azacytidine and inhibitors of ribonucleotide reductase.
    Bioorganic & medicinal chemistry, 2016, 06-01, Volume: 24, Issue:11

    Topics: Anti-HIV Agents; Azacitidine; Dose-Response Relationship, Drug; Enzyme Inhibitors; HIV Infections; HIV-1; Humans; Microbial Sensitivity Tests; Molecular Structure; Ribonucleotide Reductases; Structure-Activity Relationship

2016
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Enhancing effect by metabolic inhibitors on the killing of tumor cells by antibody and complement.
    Cancer research, 1975, Volume: 35, Issue:11 Pt 1

    Topics: Animals; Antibodies, Neoplasm; Antigen-Antibody Reactions; Antineoplastic Agents; Azacitidine; Carcinoma, Hepatocellular; Cells, Cultured; Complement System Proteins; Cyclophosphamide; Cytarabine; Dactinomycin; Doxorubicin; Fluorouracil; Guinea Pigs; Hydroxyurea; Liver Neoplasms; Mercaptopurine; Methotrexate; Mitomycins; Neoplasms, Experimental; Puromycin; Vincristine

1975
Character of the stimulatory response of uridine kinase in rat livers to cycloheximide treatment.
    European journal of biochemistry, 1975, Oct-01, Volume: 58, Issue:1

    Topics: Animals; Azacitidine; Cycloheximide; Cytarabine; Dactinomycin; Enzyme Activation; Hydroxyurea; Kinetics; Liver; Male; Mitomycins; Phosphotransferases; Puromycin; Rats; Starvation; Uridine Kinase

1975
Tumor-associated karyotypic lesions coselected with in vitro macrophage differentiation.
    Genes, chromosomes & cancer, 1992, Volume: 5, Issue:4

    Topics: Abelson murine leukemia virus; Animals; Azacitidine; Biomarkers, Tumor; Bromodeoxyuridine; Cell Adhesion; Cell Differentiation; Cell Transformation, Viral; Chromosome Aberrations; Dexamethasone; Hematopoietic Stem Cells; Hydroxyurea; Karyotyping; Leukemia, Experimental; Macrophages; Mice; Selection, Genetic; Thymus Neoplasms; Tumor Cells, Cultured

1992
Induction of erythroid differentiation and fetal hemoglobin production in human leukemic cells treated with phenylacetate.
    Blood, 1992, Sep-15, Volume: 80, Issue:6

    Topics: Azacitidine; Cell Differentiation; Cell Division; Decitabine; Erythroid Precursor Cells; Fetal Hemoglobin; Humans; Hydroxyurea; Leukemia, Experimental; Phenylacetates; Tumor Cells, Cultured

1992
CD4+ cells treated with DNA methylation inhibitors induce autologous B cell differentiation.
    Clinical immunology and immunopathology, 1990, Volume: 55, Issue:3

    Topics: Acecainide; Antibody Formation; Antigen-Presenting Cells; Antigens, CD; Antigens, Differentiation; Azacitidine; B-Lymphocytes; CD4-Positive T-Lymphocytes; Cell Differentiation; DNA; Histocompatibility Antigens; Humans; Hydroxyurea; Integrin beta1; Leukocyte Common Antigens; Methylation; Procainamide

1990
Locus control region-A gamma transgenic mice: a new model for studying the induction of fetal hemoglobin in the adult.
    Blood, 1991, Mar-15, Volume: 77, Issue:6

    Topics: Animals; Azacitidine; Base Sequence; Butyrates; Erythropoietin; Fetal Hemoglobin; Gene Expression Regulation; Genes, Regulator; Globins; Hydroxyurea; Mice; Mice, Transgenic; Molecular Sequence Data; RNA, Messenger

1991
Aspirin blocks 5-azacytidine- and hydroxyurea-induced changes in hemoglobin proportions in adult rats.
    European journal of pharmacology, 1991, Feb-07, Volume: 193, Issue:2

    Topics: Age Factors; Animals; Aspirin; Azacitidine; Fetal Hemoglobin; Hydroxyurea; Male; Rats; Rats, Inbred Strains; Reference Values

1991
A transgenic mouse model for studying the induction of fetal hemoglobin in the adult.
    Transactions of the Association of American Physicians, 1990, Volume: 103

    Topics: Adult; Animals; Azacitidine; Butyrates; Butyric Acid; Fetal Hemoglobin; Gene Expression; Globins; Humans; Hydroxyurea; Mice; Mice, Transgenic; Models, Biological

1990
Influence of cell cycle phase-specific agents on simian fetal hemoglobin synthesis.
    The Journal of clinical investigation, 1985, Volume: 75, Issue:6

    Topics: Animals; Azacitidine; Cell Cycle; Colony-Forming Units Assay; Dose-Response Relationship, Drug; Erythropoiesis; Fetal Hemoglobin; Hydroxyurea; Macaca fascicularis; Mitosis; Reticulocytes; Vinblastine

1985
Hb F production in stressed erythropoiesis: observations and kinetic models.
    Annals of the New York Academy of Sciences, 1985, Volume: 445

    Topics: Anemia; Animals; Azacitidine; Cell Cycle; Cell Differentiation; Cytarabine; Erythropoiesis; Fetal Hemoglobin; Hematopoietic Stem Cells; Humans; Hydroxyurea; Kinetics; Models, Biological; Time Factors; Transcription, Genetic

1985
Pharmacological manipulation of fetal hemoglobin synthesis in patients with severe beta-thalassemia.
    Annals of the New York Academy of Sciences, 1985, Volume: 445

    Topics: Azacitidine; Fetal Hemoglobin; Globins; Humans; Hydroxyurea; Iron; Kinetics; RNA; Thalassemia; Time Factors

1985
Pharmacologic manipulation of fetal hemoglobin synthesis.
    Progress in clinical and biological research, 1985, Volume: 191

    Topics: Anemia, Sickle Cell; Azacitidine; DNA Replication; Erythropoiesis; Fetal Hemoglobin; Gene Expression Regulation; Globins; Humans; Hydroxyurea

1985
Stimulation of protein accumulation in HeLa cells by inhibitors of DNA replication. Ferritin.
    FEBS letters, 1985, Nov-25, Volume: 193, Issue:1

    Topics: Aphidicolin; Azacitidine; Butyrates; Butyric Acid; Diterpenes; DNA Polymerase II; Ferritins; HeLa Cells; Humans; Hydroxyurea; Interphase; Iron; Thymidine

1985
Chemotherapy to increase fetal hemoglobin in patients with sickle cell anemia.
    The American journal of pediatric hematology/oncology, 1985,Fall, Volume: 7, Issue:3

    Topics: Anemia, Sickle Cell; Azacitidine; Cytarabine; Fetal Hemoglobin; Humans; Hydroxyurea; Kinetics; Thalassemia

1985
Hydroxyurea induction of hemoglobin F production in sickle cell disease: relationship between cytotoxicity and F cell production.
    Blood, 1986, Volume: 67, Issue:3

    Topics: Anemia, Sickle Cell; Azacitidine; Erythropoiesis; Fetal Hemoglobin; Hematopoietic Stem Cells; Humans; Hydroxyurea; Reticulocytes

1986
On the mechanism of Hb F elevations in the baboon by erythropoietic stress and pharmacologic manipulation.
    Blood, 1986, Volume: 67, Issue:4

    Topics: Anemia, Hemolytic; Animals; Azacitidine; Cytarabine; DNA; Erythropoiesis; Fetal Hemoglobin; Hemorrhage; Hydroxyurea; Leukocyte Count; Methylation; Nucleic Acid Hybridization; Papio; Reticulocytes

1986
Suppression of nuclear ADP-ribosyltransferase activity in Ehrlich ascites tumor cells by 5-azacytidine and its analogs.
    Biochemical and biophysical research communications, 1987, Jan-30, Volume: 142, Issue:2

    Topics: Animals; Azacitidine; Carcinoma, Ehrlich Tumor; Cell Nucleus; Cytosine; DNA; Female; Hydroxyurea; Methylation; Mice; Mice, Inbred Strains; Poly(ADP-ribose) Polymerase Inhibitors

1987
Selection of metastatic variants with identifiable karyotypic changes from a nonmetastatic murine tumor after treatment with 2'-deoxy-5-azacytidine or hydroxyurea: implications for the mechanisms of tumor progression.
    Cancer research, 1987, May-15, Volume: 47, Issue:10

    Topics: Animals; Azacitidine; Cell Division; Clone Cells; Decitabine; DNA; Female; Hydroxyurea; Karyotyping; Mammary Neoplasms, Experimental; Mathematics; Mice; Mice, Inbred CBA; Neoplasm Metastasis; Phenotype

1987
The effect of increased fetal hemoglobin production on the frequency of vaso-occlusive crisis in sickle cell disease.
    Progress in clinical and biological research, 1987, Volume: 240

    Topics: Anemia, Sickle Cell; Azacitidine; Centrifugation, Density Gradient; Erythrocytes; Fetal Hemoglobin; Humans; Hydroxyurea; Infarction; Pain

1987
Influence of hydroxyurea on fetal hemoglobin production in vitro.
    Blood, 1987, Volume: 70, Issue:6

    Topics: Anemia, Sickle Cell; Animals; Azacitidine; Cells, Cultured; Erythroblasts; Erythropoiesis; Fetal Hemoglobin; Hemoglobins; Humans; Hydroxyurea

1987
Increasing fetal hemoglobin production in sickle cell disease: results of clinical trials.
    Progress in clinical and biological research, 1987, Volume: 251

    Topics: Anemia, Sickle Cell; Azacitidine; DNA; Fetal Hemoglobin; Hematopoietic Stem Cells; Humans; Hydroxyurea; Methylation; Reticulocytes

1987
Mechanism of Hb F stimulation by S-stage compounds. In vitro studies with bone marrow cells exposed to 5-azacytidine, Ara-C, or hydroxyurea.
    The Journal of clinical investigation, 1988, Volume: 81, Issue:4

    Topics: Azacitidine; Bone Marrow Cells; Cytarabine; Erythropoiesis; Fetal Hemoglobin; Hematopoietic Stem Cells; Humans; Hydroxyurea; In Vitro Techniques; Interphase

1988
Heritable high frequency modulation of antigen expression in neoplastic cells exposed to 5-aza-2'-deoxycytidine or hydroxyurea: analysis and implications.
    Cancer research, 1988, May-01, Volume: 48, Issue:9

    Topics: Animals; Antigens, Neoplasm; Azacitidine; Decitabine; DNA, Neoplasm; Histocompatibility Antigens; Humans; Hydroxyurea; Mammary Neoplasms, Experimental; Melanoma, Experimental; Methylation; Mice; Tumor Cells, Cultured

1988
Increased metallothionein gene expression in 5-aza-2'-deoxycytidine-induced resistance to cadmium cytotoxicity.
    Chemico-biological interactions, 1988, Volume: 66, Issue:3-4

    Topics: Animals; Azacitidine; Cadmium; Cell Line; Cell Survival; Decitabine; DNA; DNA Restriction Enzymes; Dose-Response Relationship, Drug; Drug Resistance; Gene Expression Regulation; Hydroxyurea; Kinetics; Liver; Metallothionein; Methylation; Nucleic Acid Hybridization; Rats; Rats, Inbred F344

1988
Variable DNA methylation changes during differentiation of human melanoma cells.
    Experimental cell research, 1988, Volume: 178, Issue:1

    Topics: Aphidicolin; Azacitidine; Cell Differentiation; Cell Division; Chromatography, High Pressure Liquid; Cytarabine; Decitabine; Diterpenes; DNA; DNA, Neoplasm; Humans; Hydroxyurea; Methylation; Monophenol Monooxygenase; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1988
DNA methylation and polyamines in regulation of development of the fungus Mucor rouxii.
    Journal of bacteriology, 1988, Volume: 170, Issue:12

    Topics: Azacitidine; DNA, Fungal; Hydroxyurea; Methylation; Mucor; Polyamines; Putrescine; Spores, Fungal

1988
Chromatid breakage: differential effect of inhibitors of DNA synthesis during G 2 phase.
    Science (New York, N.Y.), 1972, Oct-06, Volume: 178, Issue:4056

    Topics: Animals; Azacitidine; Azaguanine; Cell Line; Chromatids; Chromosome Aberrations; Cricetinae; Cytarabine; Cytidine; DNA; DNA Nucleotidyltransferases; Hydroxyurea; Lung; Mitosis; Oxidoreductases; Pyridines; Ribonucleotides; Thiosemicarbazones; Triazines

1972
Comparison of the effectiveness of S phase inhibitors in altering gene expression.
    Biochemical and biophysical research communications, 1984, Dec-14, Volume: 125, Issue:2

    Topics: Animals; Azacitidine; Cell Line; Cell Survival; Cytarabine; Female; Genes; Hydroxyurea; Hypoxanthine Phosphoribosyltransferase; Interphase; Kinetics; Mice; Thymidine; Transcription, Genetic; X Chromosome

1984
Increasing fetal hemoglobin in sickle cell disease: comparisons of 5-azacytidine (subcutaneous or oral) with hydroxyurea.
    Transactions of the Association of American Physicians, 1984, Volume: 97

    Topics: Adult; Anemia, Sickle Cell; Azacitidine; Fetal Hemoglobin; Humans; Hydroxyurea; Middle Aged; Reticulocytes

1984
5-Azacytidine stimulates fetal hemoglobin synthesis in anemic baboons.
    Proceedings of the National Academy of Sciences of the United States of America, 1982, Volume: 79, Issue:14

    Topics: Animals; Azacitidine; Fetal Hemoglobin; Gene Expression Regulation; Globins; Hematopoiesis; Hemoglobin A; Hydroxyurea; Methylation; Papio

1982
Globin gene studies create a puzzle.
    Science (New York, N.Y.), 1984, Feb-03, Volume: 223, Issue:4635

    Topics: Anemia, Sickle Cell; Azacitidine; Cell Differentiation; Cytarabine; DNA; Erythropoiesis; Fetal Hemoglobin; Gene Expression Regulation; Hematopoietic Stem Cells; Humans; Hydroxyurea; Interphase; Methylation

1984
Augmentation of fetal-hemoglobin production in anemic monkeys by hydroxyurea.
    The New England journal of medicine, 1984, Apr-05, Volume: 310, Issue:14

    Topics: Anemia; Animals; Azacitidine; Bloodletting; DNA; Erythrocyte Count; Fetal Hemoglobin; Globins; Hydroxyurea; Macaca fascicularis; Methylation; Transcription, Genetic

1984
Hemoglobin--from F to A, and back.
    The New England journal of medicine, 1984, Apr-05, Volume: 310, Issue:14

    Topics: Anemia, Sickle Cell; Azacitidine; DNA; Fetal Hemoglobin; Humans; Hydroxyurea; Methylation; Thalassemia

1984
Sickle cell paths converge on hydroxyurea.
    Nature medicine, 1995, Volume: 1, Issue:4

    Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Azacitidine; Child; Fetal Hemoglobin; Hemoglobin, Sickle; Humans; Hydroxyurea; Mutation

1995
Enhanced fetal hemoglobin production by phenylacetate and 4-phenylbutyrate in erythroid precursors derived from normal donors and patients with sickle cell anemia and beta-thalassemia.
    Blood, 1993, Oct-01, Volume: 82, Issue:7

    Topics: Anemia, Sickle Cell; Azacitidine; beta-Thalassemia; Blotting, Northern; Butyrates; Butyric Acid; Cell Division; Cells, Cultured; DNA Probes; Erythrocytes; Fetal Hemoglobin; Hematopoietic Stem Cells; Humans; Hydroxyurea; Kinetics; Phenylacetates; Phenylbutyrates; Reference Values

1993
Quantitative PCR analysis of HbF inducers in primary human adult erythroid cells.
    Blood, 2000, Feb-01, Volume: 95, Issue:3

    Topics: Adult; Azacitidine; Butyric Acid; DNA, Complementary; Erythroid Precursor Cells; Erythropoietin; Fetal Hemoglobin; Gene Expression Regulation; Globins; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Hydroxyurea; Polymerase Chain Reaction; RNA, Messenger

2000
2-deoxy 5-azacytidine and fetal hemoglobin induction in sickle cell anemia.
    Blood, 2000, Oct-01, Volume: 96, Issue:7

    Topics: Adolescent; Adult; Anemia, Sickle Cell; Azacitidine; Blood Cell Count; Cohort Studies; Decitabine; Erythrocyte Count; Female; Fetal Hemoglobin; Globins; Humans; Hydroxyurea; Male; Middle Aged; Neutrophils; Platelet Count; Reticulocytes

2000
Treatment of thalassoemia--the current scenario.
    Journal of the Indian Medical Association, 2002, Volume: 100, Issue:2

    Topics: Azacitidine; Bone Marrow Transplantation; Deferiprone; Fetal Hemoglobin; Genetic Therapy; Humans; Hydroxyurea; Iron Chelating Agents; Pyridones; Thalassemia

2002
Induction of fetal hemoglobin expression by the histone deacetylase inhibitor apicidin.
    Blood, 2003, Mar-01, Volume: 101, Issue:5

    Topics: Amides; Azacitidine; Benzamides; Butyrates; Enzyme Inhibitors; Fetal Hemoglobin; Gene Expression Regulation; Gene Expression Regulation, Leukemic; Globins; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Humans; Hydroxamic Acids; Hydroxyurea; Imidazoles; K562 Cells; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Neoplasm Proteins; p38 Mitogen-Activated Protein Kinases; Peptides, Cyclic; Phenylbutyrates; Pyridines; Vorinostat

2003
Reactivation of fetal hemoglobin in adult stem cell erythropoiesis by transforming growth factor-beta.
    Journal of hematotherapy & stem cell research, 2003, Volume: 12, Issue:5

    Topics: Adult; Antigens, CD34; Azacitidine; Butyrates; Cell Count; Cell Differentiation; Cells, Cultured; Dose-Response Relationship, Drug; Erythropoiesis; Fetal Hemoglobin; Flow Cytometry; Hematopoietic Stem Cells; Hemoglobins; Humans; Hydroxyurea; Time Factors; Transforming Growth Factor beta

2003
Approaches to the reactivation of hemoglobin F as a treatment for sickle cell disease.
    Clinical advances in hematology & oncology : H&O, 2004, Volume: 2, Issue:1

    Topics: Acetylation; Anemia, Sickle Cell; Azacitidine; Clinical Trials as Topic; CpG Islands; Decitabine; Disease Management; DNA Methylation; Erythrocytes, Abnormal; Fetal Hemoglobin; Gene Silencing; Globins; Hemoglobin, Sickle; Histone Deacetylase Inhibitors; Humans; Hydroxyurea; Phenylbutyrates; Protein Processing, Post-Translational; Up-Regulation

2004
Current therapy of sickle cell disease.
    Haematologica, 2006, Volume: 91, Issue:1

    Topics: Acetamides; Anemia, Sickle Cell; Azacitidine; Butyrates; Decitabine; Erythrocyte Transfusion; Humans; Hydroxyurea; Nitric Oxide; Trityl Compounds

2006
Trisomy 19 as the sole chromosomal abnormality in proliferative chronic myelomonocytic leukemia.
    Leukemia research, 2006, Volume: 30, Issue:8

    Topics: Aged; Azacitidine; Chromosome Aberrations; Chromosomes, Human, Pair 19; Cytarabine; Cytogenetic Analysis; Daunorubicin; Decitabine; Dose-Response Relationship, Drug; Fatal Outcome; Female; Humans; Hydroxyurea; Leukemia, Myelomonocytic, Chronic; Male; Middle Aged; Myelodysplastic Syndromes; Phenotype; Steroids; Treatment Outcome

2006
Role of cyclic nucleotides in fetal hemoglobin induction in cultured CD34+ cells.
    Experimental hematology, 2006, Volume: 34, Issue:9

    Topics: Adenylyl Cyclases; Antigens, CD34; Antisickling Agents; Azacitidine; Butyrates; Colforsin; Cyclic AMP; Cyclic GMP; Decitabine; Enzyme Inhibitors; Erythroid Cells; Fetal Hemoglobin; Humans; Hydroxyurea; K562 Cells; Monocytes; RNA, Messenger

2006
Hydroxycarbamide in combination with azacitidine or decitabine is antagonistic on DNA methylation inhibition.
    British journal of haematology, 2007, Volume: 138, Issue:5

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Aphidicolin; Azacitidine; Cell Cycle; Decitabine; DNA Methylation; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Administration Schedule; Enzyme Inhibitors; Humans; Hydroxyurea; Tumor Cells, Cultured

2007
DNA hypomethylation therapies and hemoglobin disorders. [An interview with Hassana Fathallah by H&O].
    Clinical advances in hematology & oncology : H&O, 2008, Volume: 6, Issue:11

    Topics: Anemia, Sickle Cell; Antineoplastic Agents; Azacitidine; beta-Thalassemia; Decitabine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Enzyme Inhibitors; Fetal Hemoglobin; Histone Acetyltransferases; Humans; Hydroxyurea

2008
Combining gene therapy and fetal hemoglobin induction for treatment of β-thalassemia.
    Expert review of hematology, 2013, Volume: 6, Issue:3

    Topics: Antisickling Agents; Azacitidine; beta-Globins; beta-Thalassemia; Decitabine; Fetal Hemoglobin; Genetic Therapy; Genetic Vectors; Humans; Hydroxyurea; Lentivirus; Retroviridae; Thalidomide

2013
[Cutaneous infiltratiton by chronic myelononocytic leukemia: presentation of three cases].
    Dermatology online journal, 2013, Nov-15, Volume: 19, Issue:11

    Topics: Aged; Antineoplastic Agents; Azacitidine; Cytarabine; Fatal Outcome; Humans; Hydroxyurea; Leukemia, Myelomonocytic, Chronic; Leukemic Infiltration; Male; Skin

2013
Seed response to strigolactone is controlled by abscisic acid-independent DNA methylation in the obligate root parasitic plant, Phelipanche ramosa L. Pomel.
    Journal of experimental botany, 2015, Volume: 66, Issue:11

    Topics: Abscisic Acid; Azacitidine; Base Sequence; Cytochrome P-450 Enzyme System; DNA Methylation; Enzyme Inhibitors; Epigenesis, Genetic; Germination; Hydroxyurea; Lactones; Molecular Sequence Data; Orobanche; Plant Dormancy; Plant Growth Regulators; Plant Proteins; Plant Roots; Seeds; Sequence Analysis, DNA

2015
Hydroxymethylcytosine and demethylation of the γ-globin gene promoter during erythroid differentiation.
    Epigenetics, 2015, Volume: 10, Issue:5

    Topics: 5-Methylcytosine; Animals; Animals, Newborn; Antineoplastic Agents; Ascorbic Acid; Azacitidine; Bone Marrow Cells; Cell Differentiation; Cells, Cultured; Cytosine; Decitabine; Dioxygenases; DNA Methylation; Erythroid Cells; gamma-Globins; Histone Demethylases; Humans; Hydroxyurea; Liver; Papio anubis; Promoter Regions, Genetic; Tranylcypromine

2015
Outcome of Lower-Risk Patients With Myelodysplastic Syndromes Without 5q Deletion After Failure of Erythropoiesis-Stimulating Agents.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2017, May-10, Volume: 35, Issue:14

    Topics: Aged; Aged, 80 and over; Anemia; Antilymphocyte Serum; Antineoplastic Agents; Arsenic; Azacitidine; Chromosome Deletion; Chromosomes, Human, Pair 5; Cyclosporine; Cytarabine; Decitabine; Disease Progression; Enzyme Inhibitors; Erythrocyte Transfusion; Female; Hematinics; Humans; Hydroxyurea; Immunologic Factors; Lenalidomide; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Recurrence; Retreatment; Retrospective Studies; Risk Factors; Survival Rate; Thalidomide; Treatment Failure; Tretinoin; Valproic Acid

2017
Favorable evolution of lung interstitial disease in a patient with chronic myelomonocytic leukemia treated with azacitidine.
    Annals of hematology, 2018, Volume: 97, Issue:3

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Combined Modality Therapy; Drug Resistance; Humans; Hydroxyurea; Leukemia, Myelomonocytic, Chronic; Lung Diseases, Interstitial; Male; Middle Aged; Oxygen Inhalation Therapy; Prednisone; Tomography, X-Ray Computed

2018
Establishment and validation of a novel risk model for estimating time to first treatment in 120 patients with chronic myelomonocytic leukaemia.
    Wiener klinische Wochenschrift, 2018, Volume: 130, Issue:3-4

    Topics: Adult; Aged; Aged, 80 and over; Azacitidine; Female; Humans; Hydroxyurea; Leukemia, Myelomonocytic, Chronic; Male; Middle Aged; Myelodysplastic Syndromes; Prognosis; Retrospective Studies; Time Factors

2018
Treatment of Philadelphia-negative myeloproliferative neoplasms in accelerated/blastic phase with azacytidine. Clinical results and identification of prognostic factors.
    Hematological oncology, 2019, Volume: 37, Issue:3

    Topics: Aged; Antimetabolites, Antineoplastic; Azacitidine; Blast Crisis; Female; Humans; Hydroxyurea; Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative; Male; Melphalan; Middle Aged; Mutation; Myeloproliferative Disorders; Pipobroman; Polycythemia Vera; Primary Myelofibrosis; Prognosis; Remission Induction; Retrospective Studies; Thrombocythemia, Essential; Treatment Outcome

2019
Real-world data on treatment patterns and outcomes of hypomethylating therapy in patients with newly diagnosed acute myeloid leukaemia aged ≥ 60 years.
    British journal of haematology, 2020, Volume: 189, Issue:1

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cytarabine; Decitabine; Disease-Free Survival; Female; Follow-Up Studies; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Male; Middle Aged; Retrospective Studies; Survival Rate

2020
Outcomes of patients with chronic myelomonocytic leukaemia treated with non-curative therapies: a retrospective cohort study.
    The Lancet. Haematology, 2021, Volume: 8, Issue:2

    Topics: Aged; Antineoplastic Agents; Azacitidine; Female; Humans; Hydroxyurea; Kaplan-Meier Estimate; Leukemia, Myelomonocytic, Chronic; Male; Middle Aged; Prognosis; Proportional Hazards Models; Retrospective Studies; Treatment Outcome

2021
Treatment options and survival in real life during the past three decades in patients with chronic myelomonocytic leukemia.
    Wiener medizinische Wochenschrift (1946), 2023, Volume: 173, Issue:1-2

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Humans; Hydroxyurea; Leukemia, Myelomonocytic, Chronic; Retrospective Studies

2023