azacitidine and glycine

azacitidine has been researched along with glycine in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.00)18.7374
1990's0 (0.00)18.2507
2000's1 (5.00)29.6817
2010's8 (40.00)24.3611
2020's10 (50.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Martin, DW; Owen, NT1
Albrecht, S; Berthold, F; Goodyer, CG; Koch, A; Meyer-Puttlitz, B; Pietsch, T; Sörensen, N; Tonn, JC; Waha, A; Weggen, S; Wiestler, OD1
Jabbour, E; Kadia, TM; Kantarjian, H1
List, AF1
Becker, PS; Dean, C; Deeg, HJ; Estey, E; Hendrie, P; Mawad, R; Myint, H; Pagel, JM; Sandhu, V; Scott, B; Singer, JW; Walter, R; Wang, L; Wood, BL1
Al-Kali, A; Atallah, E; Azarnia, N; Baer, MR; Collins, R; Fenaux, P; Gaidano, G; Garcia-Manero, G; Godley, LA; Greenberg, P; Jabbour, E; Kambhampati, S; Kantarjian, H; Kreuzer, KA; Platzbecker, U; Roboz, GJ; Scott, BL; Sekeres, MA; Silverman, LR; Steensma, DP; Wilhelm, FE1
Navada, SC; Silverman, LR1
Allen, JE; Babar, J; Benes, CH; Claxton, DF; Dicker, DT; El-Deiry, WS; Garnett, MJ; Grupp, SA; Hall, J; Khan, N; Kline, CLB; Lulla, AR; McDermott, U; Oster, W; Prabhu, VV; Pu, JJ; Talekar, MK; Van den Heuvel, APJ; Zhou, L1
Azarnia, N; Fenaux, P; Fruchtman, SM; Garcia-Manero, G; Kantarjian, H; Komrokji, R; Nazha, A; Platzbecker, U; Prebet, T; Roboz, G; Santini, V; Sekeres, MA; Silverman, LR; Steensma, DP; Zbyszewski, PS1
Carraway, HE; Chandhok, NS; Griffiths, EA; Prebet, T1
Alvarado, Y; Demakos, EP; Fruchtman, SM; Garcia-Manero, G; John, RB; Maniar, M; Navada, SC; OdchimarReissig, R; Ohanian, MN; Pemmaraju, N; Silverman, LR; Woodman, RC; Zbyszewski, PS1
Curcio, T; Desai, P; Edirisinghe, B; Lee, S; Pianello, S; Ritchie, EK; Roboz, GJ; Samuel, M1
Choe, S; Daigle, S; de Botton, S; DiNardo, CD; Döhner, H; Fan, B; Fathi, AT; Frankfurt, O; Franovic, A; Frattini, MG; Gianolio, DA; Goldwasser, M; Gong, J; Kantarjian, HM; Lersch, F; Martinelli, G; Patel, PA; Raffoux, E; Schuh, AC; Stein, AS; Stein, EM; Stone, RM; Tan, P; Vyas, P; Winkler, T; Wu, B; Zeidan, AM; Zhang, V1
Bertani, G; Calado, RT; Daigle, SR; de Botton, S; Döhner, H; Gianolio, DA; Heuser, M; Hui, J; Montesinos, P; Pandya, SS; Recher, C; Schuh, AC; Vives, S; Wang, J; Yeh, SP; Zarzycka, E1
Briceño-Casado, MP; Gil-Sierra, MD; Sierra-Sanchez, JF1
Goodman, AM; Mohyuddin, GR; Prasad, V1
de Botton, S; Döhner, H; Montesinos, P1
Takahashi, K1

Reviews

4 review(s) available for azacitidine and glycine

ArticleYear
Failure of hypomethylating agent-based therapy in myelodysplastic syndromes.
    Seminars in oncology, 2011, Volume: 38, Issue:5

    Topics: Adenine Nucleotides; Alemtuzumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Neoplasm; Antineoplastic Agents; Arabinonucleosides; Azacitidine; Clofarabine; Cytosine; Decitabine; Drug Resistance; Drug Substitution; Enzyme Inhibitors; Glutathione; Glycine; Humans; Myelodysplastic Syndromes; Stem Cell Transplantation; Sulfones; Treatment Failure

2011
New therapeutics for myelodysplastic syndromes.
    Leukemia research, 2012, Volume: 36, Issue:12

    Topics: Antineoplastic Agents; Azacitidine; Bone Marrow; Chromosomes, Human, Pair 5; Glycine; Humans; Hydroxamic Acids; Lenalidomide; Myelodysplastic Syndromes; Neoplastic Stem Cells; p38 Mitogen-Activated Protein Kinases; Sequence Deletion; Sulfones; Thalidomide; Transforming Growth Factor beta; Tumor Microenvironment

2012
The safety and efficacy of rigosertib in the treatment of myelodysplastic syndromes.
    Expert review of anticancer therapy, 2016, Volume: 16, Issue:8

    Topics: Azacitidine; Disease Progression; Drug Therapy, Combination; Glycine; Humans; Myelodysplastic Syndromes; Prognosis; Sulfones; Survival Rate; Treatment Outcome

2016
Advances in non-intensive chemotherapy treatment options for adults diagnosed with acute myeloid leukemia.
    Leukemia research, 2020, Volume: 91

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Benzimidazoles; Bridged Bicyclo Compounds, Heterocyclic; Cytarabine; Decitabine; Gemtuzumab; Glycine; Humans; Leukemia, Myeloid, Acute; Male; Molecular Targeted Therapy; Phenylurea Compounds; Precision Medicine; Pyridines; Recurrence; Remission Induction; Staurosporine; Sulfonamides

2020

Trials

7 trial(s) available for azacitidine and glycine

ArticleYear
Phase II study of tosedostat with cytarabine or decitabine in newly diagnosed older patients with acute myeloid leukaemia or high-risk MDS.
    British journal of haematology, 2016, Volume: 172, Issue:2

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cytarabine; Decitabine; Female; Glycine; Humans; Hydroxamic Acids; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Remission Induction; Survival Analysis; Treatment Outcome

2016
Rigosertib versus best supportive care for patients with high-risk myelodysplastic syndromes after failure of hypomethylating drugs (ONTIME): a randomised, controlled, phase 3 trial.
    The Lancet. Oncology, 2016, Volume: 17, Issue:4

    Topics: Aged; Azacitidine; Decitabine; Disease-Free Survival; DNA Methylation; Drug Administration Schedule; Europe; Female; Glycine; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Myelodysplastic Syndromes; Risk; Sulfones; Treatment Outcome

2016
Validation of a post-hypomethylating agent failure prognostic model in myelodysplastic syndromes patients treated in a randomized controlled phase III trial of rigosertib vs. best supportive care.
    Blood cancer journal, 2017, 12-14, Volume: 7, Issue:12

    Topics: Antineoplastic Agents; Azacitidine; Decitabine; Drug Resistance, Neoplasm; Glycine; Humans; Kaplan-Meier Estimate; Myelodysplastic Syndromes; Prognosis; Sulfones; Treatment Outcome

2017
Rigosertib in combination with azacitidine in patients with myelodysplastic syndromes or acute myeloid leukemia: Results of a phase 1 study.
    Leukemia research, 2020, Volume: 94

    Topics: Adult; Aged; Aged, 80 and over; Azacitidine; Female; Glycine; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Sulfones

2020
Phase II study of the clinical efficacy and safety of tosedostat in patients with myelodysplastic syndromes (MDS) after failure of hypomethylating agent-based therapy.
    Leukemia & lymphoma, 2021, Volume: 62, Issue:2

    Topics: Azacitidine; DNA Methylation; Glycine; Humans; Hydroxamic Acids; Myelodysplastic Syndromes; Treatment Outcome

2021
Mutant Isocitrate Dehydrogenase 1 Inhibitor Ivosidenib in Combination With Azacitidine for Newly Diagnosed Acute Myeloid Leukemia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2021, 01-01, Volume: 39, Issue:1

    Topics: Aged; Aged, 80 and over; Apoptosis; Azacitidine; Drug Therapy, Combination; Enzyme Inhibitors; Female; Glycine; Humans; Isocitrate Dehydrogenase; Leukemia, Myeloid, Acute; Male; Middle Aged; Pyridines

2021
Ivosidenib and Azacitidine in
    The New England journal of medicine, 2022, 04-21, Volume: 386, Issue:16

    Topics: Antineoplastic Agents; Azacitidine; Febrile Neutropenia; Glycine; Humans; Isocitrate Dehydrogenase; Leukemia, Myeloid, Acute; Leukopenia; Pyridines; Recurrence

2022

Other Studies

9 other study(ies) available for azacitidine and glycine

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Repression and derepression of purine biosynthesis in mammalian hepatoma cells in culture.
    The Journal of biological chemistry, 1972, Sep-10, Volume: 247, Issue:17

    Topics: Acyltransferases; Adenine; Animals; Azacitidine; Carbon Isotopes; Carcinoma, Hepatocellular; Clone Cells; Cycloheximide; Dactinomycin; Feedback; Formates; Glycine; Kinetics; Ligases; Liver Neoplasms; Neoplasms, Experimental; Pentosephosphates; Pentosyltransferases; Purines; Rats; Ribonucleotides; Ribose; Tetrahydrofolates; Tritium

1972
Epigenetic silencing of the HIC-1 gene in human medulloblastomas.
    Journal of neuropathology and experimental neurology, 2003, Volume: 62, Issue:11

    Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Azacitidine; Blotting, Northern; Cerebellar Neoplasms; Child; Child, Preschool; Cystine; Decitabine; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Glycine; Humans; Infant; Loss of Heterozygosity; Male; Medulloblastoma; Methylation; Middle Aged; Molecular Sequence Data; Myogenic Regulatory Factors; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; RNA, Messenger; Sulfites; Tumor Cells, Cultured

2003
Single agent and synergistic combinatorial efficacy of first-in-class small molecule imipridone ONC201 in hematological malignancies.
    Cell cycle (Georgetown, Tex.), 2018, Volume: 17, Issue:4

    Topics: Activating Transcription Factor 4; Animals; Antineoplastic Agents; Apoptosis; Azacitidine; Boron Compounds; Cell Line, Tumor; Cell Survival; Drug Screening Assays, Antitumor; Drug Synergism; G1 Phase Cell Cycle Checkpoints; Glycine; Hematologic Neoplasms; Heterocyclic Compounds, 4 or More Rings; Humans; Imidazoles; Mice; Mice, SCID; Pyridines; Pyrimidines; Transcription Factor CHOP; Transplantation, Heterologous

2018
Ivosidenib Boosts OS with Azacitidine in AML.
    Cancer discovery, 2022, 07-06, Volume: 12, Issue:7

    Topics: Azacitidine; Glycine; Humans; Leukemia, Myeloid, Acute; Pyridines

2022
Ivosidenib and Azacitidine in IDH1-Mutated AML.
    The New England journal of medicine, 2022, 06-30, Volume: 386, Issue:26

    Topics: Azacitidine; Glycine; Humans; Isocitrate Dehydrogenase; Leukemia, Myeloid, Acute; Pyridines

2022
Ivosidenib and Azacitidine in IDH1-Mutated AML.
    The New England journal of medicine, 2022, 06-30, Volume: 386, Issue:26

    Topics: Azacitidine; Glycine; Humans; Isocitrate Dehydrogenase; Leukemia, Myeloid, Acute; Pyridines

2022
Ivosidenib and Azacitidine in IDH1-Mutated AML. Reply.
    The New England journal of medicine, 2022, 06-30, Volume: 386, Issue:26

    Topics: Azacitidine; Glycine; Humans; Isocitrate Dehydrogenase; Leukemia, Myeloid, Acute; Pyridines

2022
Is Induction of Hypomethylation with Ivosidenib and 5-Azacitidine Curative Regimen against IDH1-Mutated Acute Myeloid Leukemia?
    Anti-cancer agents in medicinal chemistry, 2023, Volume: 23, Issue:8

    Topics: Azacitidine; Glycine; Humans; Isocitrate Dehydrogenase; Leukemia, Myeloid, Acute; Mutation; Pyridines

2023