azacitidine and deoxycytidine

azacitidine has been researched along with deoxycytidine in 74 studies

Research

Studies (74)

Timeframe	Studies, this research(%)	All Research%
pre-1990	24 (32.43)	18.7374
1990's	10 (13.51)	18.2507
2000's	13 (17.57)	29.6817
2010's	25 (33.78)	24.3611
2020's	2 (2.70)	2.80

Authors

Authors	Studies
Cook, PD; McNamara, DJ	1
Karon, M; Lee, T; Monparler, RL	1
Chabner, BA; Coleman, CN; Drake, JC; Stoller, RG	1
Goodman, J; Momparler, RL	1
Abbasi, MM; Beisler, JA; Voytek, P; Wolpert-DeFilippes, MK	1
Cihák, A; Veselý, J	5
Gonzales, FA; Momparier, RL	1
Derse, D; Momparler, RL	1
Constantinides, PG; Jones, PA; Taylor, SM	1
Chou, TC; Kong, XB; Tong, WP	1
Call, KM; Thilly, WG	1
Brown, TD; Burris, HA; Havlin, KA; O'Rourke, TJ; Rodriguez, GI; Wall, JG; Weiss, GR	1
Greig, R; Kline, T; Mallon, F; Poste, G; Trainer, DL	1
Cooper, IA; Crowther, PJ; Simmons, DL; Woodcock, DM	1
Ahluwalia, GS; Arnold, ST; Balzarini, J; Cohen, MB; Cooney, DA; Dalal, M; Johns, DG; Kang, GJ; McMahon, JB; Wilson, YA	1
Kaysen, J; Kufe, D; Spriggs, D	1
Bhalla, K; Gleyzer, M; Grant, S	1
Arlin, Z; Baker, M; Bhalla, K; Cole, J; Graham, G; Grant, S; MacLaughlin, W	1
Veselý, J	1
Harris, CC; Masui, T; Smith, RA; Wilson, VL	1
Jones, PA; Taylor, SM	1
Niwa, O; Sugahara, T	1
Barr, PJ; Garrett, CE; Santi, DV	1
Augusti-Tocco, G; Bartolucci, S; Carpinelli, P; Granata, F; Rossi, M	1
Bøyum, A; Løvhaug, D; Nordlie, EM; Seeberg, E	1
Caspary, WJ; Gibis, P; Körber, C; Spencer, DL; Stopper, H	1
Honders, MW; Kester, MG; Landegent, JE; Stegmann, AP; Willemze, R	1
Ahluwalia, GS; Barchi, JJ; Cooney, DA; Covey, JM; Gharehbaghi, K; Hochman, I; Jayaram, HN; Paull, KD	1
Cournoyer, D; Eliopoulos, N; Momparler, RL	1
Beauséjour, C; Eliopoulos, N; Momparler, RL	1
Fukamachi, H; Higo, T; Kai, M; Kaito, C; Sekimizu, K; Shiokawa, K; Takayama, E	1
Beauséjour, CM; Eliopoulos, N; Le, NL; Momparler, L; Momparler, RL	1
Beauséjour, CM; Gagnon, J; Momparler, RL; Primeau, M	1
Crnogorac-Jurcevic, T; Donadelli, M; Lemoine, NR; Missiaglia, E; Palmieri, M; Scarpa, A	1
Cherry, JC; Farrar, WL; Fox, SD; Hodge, DR; Hurt, EM; Kelley, JA; Munroe, DJ; Peng, B	1
Chuang, JC; Jones, PA; Kwan, JM; Li, TW; Liang, G; Yang, AS; Yoo, CB	1
Blum, W; Byrd, J; Chan, KK; Klisovic, R; Liu, S; Liu, Z; Marcucci, G; Paschka, P; Perrotti, D; Xie, Z	1
Allen, Y; Aniagu, SO; Chipman, JK; Katsiadaki, I; Williams, TD	1
Campanella, C; Cantero, G; Cortés, F; Domínguez, I; Mateos, S; Pastor, N	1
Ammerpohl, O; Fölsch, UR; Kalthoff, H; Koch, D; Müerköster, SS; Schäfer, H; Sipos, B; Tsao, MS; Werbing, V	1
Miyazawa, K	1
Fukushige, S; Horii, A; Kondo, E	1
Chan, KK; Fan-Havard, P; Huang, TH; Liu, S; Liu, Z; Marcucci, G; Plass, C; Wu, J; Xie, Z	1
Betham, B; Bhagwat, AS; Marquez, VE; Shalhout, S	1
Iwata, H; Miyazawa, M; Sato, H; Takano, Y; Ueno, K; Virgona, N; Yano, T; Yano, Y	1
Garcia-Manero, G; Quintás-Cardama, A; Santos, FP	1
Clouser, CL; Mansky, LM; Patterson, SE	1
Buckley, B; Fortin, MC; Richardson, JR; Yang, I	1
Gordian, E; Miller, H; Ramachandran, K; Rocha-Lima, C; Singal, R	1
Shen, H; Suo, Y; Wang, H; Wang, X; Yin, R	1
Clouser, CL; Greggs, WM; Mansky, LM; Patterson, SE	1
Briggs, JE; Clouser, CL; Crankshaw, DL; Holtz, CM; Mansky, LM; Mullett, M; O'Sullivan, MG; Patterson, SE	1
Cass, CE; Damaraju, VL; Mowles, D; Ng, A; Tong, Z; Yao, S; Young, JD	1
Andersson, BS; Champlin, RE; Li, Y; Murray, D; Nieto, Y; Valdez, BC; Wang, G	1
Cogdill, AP; Cooper, ZA; Ferrone, CR; Fiedler, A; Frederick, DT; Garber, HR; Rosenberg, L; Thayer, SP; Wargo, JA; Warshaw, AL	1
Almgren, M; Baird, AM; Dockry, E; Ekström, TJ; Gray, SG; Hollywood, D; Meunier, A; Nikolaidis, G; O'Byrne, KJ; O'Kelly, F; Perry, AS	1
Bonnac, L; Clouser, CL; Mansky, LM; Patterson, SE	1
Andrews, PW; Li, J; Wongtrakoongate, P	1
Allan, PW; Hollingshead, M; Maddry, JA; Maxuitenko, YY; Parker, WB; Sambandam, V; Thottassery, JV; Tiwari, K	1
Essigmann, JM; Fedeles, BI; Li, D; Peng, CS; Silvestre, KJ; Simi, AK; Simpson, JH; Singh, V; Tokmakoff, A	1
Chao, MR; Chen, JL; Hsu, YW; Hu, CW; Yen, CC	1
Berda, Y; Ciccolini, J; Costello, R; Fanciullino, R; Fina, F; Lacarelle, B; Mercier, C; Ouafik, L; Serdjebi, C	1
Aiba, K; Hayashi, K; Homma, S; Ito, M; Kamata, Y; Kan, S; Nagasaki, E	1
Ahmed, S; Alousi, A; Anderlini, P; Andersson, BS; Bashir, Q; Champlin, R; Dabaja, B; Fanale, M; Gulbis, A; Hosing, C; Jones, RB; Myers, A; Nieto, Y; Oki, Y; Pinnix, C; Popat, U; Qazilbash, M; Shah, N; Shpall, EJ; Thall, PF; Valdez, BC; Wei, W	1
Cruz-Vallejo, V; Morales-Ramírez, P; Vallarino-Kelly, T	1
Fukuda, M; Hosokawa, M; Iwakawa, S; Masuda, A; Tanaka, S; Ueda, K	1
Chen, H; Ding, X; Hua, CS; Ma, DC; Wang, WS; Wu, F; Zhang, CD; Zhao, J	1
Beijnen, JH; Lucas, L; Oganesian, A; Roosendaal, J; Rosing, H; Schellens, JHM	1
Alvarez Secord, A; Armstrong, DK; Azab, M; Banerjee, S; Basu, B; Birrer, MJ; Blagden, SP; Braly, P; Fleming, GF; Ghamande, S; Hall, GD; Hao, Y; Hirte, HW; Jueliger, S; Keer, H; Kristeleit, R; Markham, MJ; Matei, D; Matulonis, UA; McGuire, WP; Naim, S; Nemunaitis, J; Nephew, KP; Oganesian, A; Oza, AM; Provencher, DM; Roman, LD; Schwartz, B	1
Kavoosi, F; Sanaei, M	1

Reviews

5 review(s) available for azacitidine and deoxycytidine

Article	Year
New anticancer agents. Cancer chemotherapy and biological response modifiers, 1991, Volume: 12 Topics: Alkaloids; Animals; Antineoplastic Agents; Azacitidine; Biphenyl Compounds; Chrysenes; Deoxycytidine; Echinomycin; Epirubicin; Etanidazole; Flavonoids; Gemcitabine; Guanidines; Humans; Idarubicin; Menogaril; Mitoguazone; Neoplasms; Nitroimidazoles; Nogalamycin; Organoplatinum Compounds; Paclitaxel; Pentostatin; Polymers; Propylene Glycols; Ribavirin; Sulfonylurea Compounds; Trimetrexate; Vidarabine Phosphate	1991
Resistance of mammalian tumour cells toward pyrimidine analogues. A review. Oncology, 1973, Volume: 28, Issue:3 Topics: Animals; Antimetabolites; Azacitidine; Azauridine; Bromouracil; Carcinoma, Ehrlich Tumor; Cell Line; Cricetinae; Cytarabine; Deoxycytidine; Drug Resistance; Fluorouracil; Genetic Code; Leukemia, Experimental; Leukemia, Lymphoid; Mast-Cell Sarcoma; Mice; Mutation; Neoplasms, Experimental; Oncogenic Viruses; Phosphotransferases; Pyrimidines; Sarcoma, Experimental; Selection, Genetic; Thymidine Kinase; Uracil; Virus Replication	1973
Chemoprotection against cytosine nucleoside analogs using the human cytidine deaminase gene. Progress in experimental tumor research, 1999, Volume: 36 Topics: Antimetabolites, Antineoplastic; Azacitidine; Cytarabine; Cytidine Deaminase; Decitabine; Deoxycytidine; Drug Resistance; Gemcitabine; Humans	1999
[Pathogenesis of and therapeutic progress for myelodysplastic syndromes]. [Rinsho ketsueki] The Japanese journal of clinical hematology, 2008, Volume: 49, Issue:10 Topics: Azacitidine; Clinical Trials as Topic; Decitabine; Deoxycytidine; DNA Methylation; Drug Design; Gene Targeting; Humans; Iron Chelating Agents; Lenalidomide; Myelodysplastic Syndromes; Thalidomide; Tumor Necrosis Factor-alpha	2008
Therapy with azanucleosides for myelodysplastic syndromes. Nature reviews. Clinical oncology, 2010, Volume: 7, Issue:8 Topics: Antimetabolites, Antineoplastic; Azacitidine; Chromosomes, Human, Pair 7; Decitabine; Deoxycytidine; Disease Progression; DNA Methylation; Drug Therapy, Combination; Humans; Myelodysplastic Syndromes; Risk Assessment; Treatment Outcome	2010

Trials

1 trial(s) available for azacitidine and deoxycytidine

Article	Year
A Randomized Phase II Trial of Epigenetic Priming with Guadecitabine and Carboplatin in Platinum-resistant, Recurrent Ovarian Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research, 2020, 03-01, Volume: 26, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Carboplatin; Deoxycytidine; Doxorubicin; Drug Resistance, Neoplasm; Epigenesis, Genetic; Female; Gemcitabine; Humans; Middle Aged; Neoplasm Recurrence, Local; Ovarian Neoplasms; Paclitaxel; Patient Safety; Polyethylene Glycols; Survival Rate; Topotecan; Treatment Outcome	2020

Article

Year

A Randomized Phase II Trial of Epigenetic Priming with Guadecitabine and Carboplatin in Platinum-resistant, Recurrent Ovarian Cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research, 2020, 03-01, Volume: 26, Issue:5

Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Carboplatin; Deoxycytidine; Doxorubicin; Drug Resistance, Neoplasm; Epigenesis, Genetic; Female; Gemcitabine; Humans; Middle Aged; Neoplasm Recurrence, Local; Ovarian Neoplasms; Paclitaxel; Patient Safety; Polyethylene Glycols; Survival Rate; Topotecan; Treatment Outcome

2020

Other Studies

68 other study(ies) available for azacitidine and deoxycytidine

Article	Year
Synthesis and antitumor activity of fluorine-substituted 4-amino-2(1H)-pyridinones and their nucleosides. 3-Deazacytosines. Journal of medicinal chemistry, 1987, Volume: 30, Issue:2 Topics: Animals; Antimetabolites, Antineoplastic; Cytosine; Drug Evaluation, Preclinical; Indicators and Reagents; Leukemia L1210; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mice; Spectrophotometry; Structure-Activity Relationship	1987
Cellular phosphorylation of 1-beta-D-arabinofuranosylcytosine 5-azacytidine with intact fibrosarcoma and leukemic cells. Cancer research, 1975, Volume: 35, Issue:9 Topics: Animals; Azacitidine; Binding, Competitive; Cells, Cultured; Cricetinae; Cytarabine; Cytidine; Deoxycytidine; Drug Resistance; Fibrosarcoma; Kinetics; Leukemia, Experimental; Mice; Phosphorus; Sarcoma, Experimental	1975
Deoxycytidine kinase: properties of the enzyme from human leukemic granulocytes. Blood, 1975, Volume: 46, Issue:5 Topics: Azacitidine; Blood Proteins; Cell Separation; Cell-Free System; Cytarabine; Cytidine Deaminase; Deoxycytidine; Granulocytes; Humans; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Molecular Weight; Phosphates; Phosphotransferases; Tissue Extracts; Uridine Kinase	1975
In vitro cytotoxic and biochemical effects of 5-aza-2'-deoxycytidine. Cancer research, 1977, Volume: 37, Issue:6 Topics: Azacitidine; Cell Division; Cell Survival; Cells, Cultured; Cytidine; Deoxycytidine; DNA, Neoplasm; Fibrosarcoma; Neoplasm Proteins; Neoplasms, Experimental; RNA, Neoplasm	1977
Comparative studies of the cytostatic action and metabolism of 5-azacytidine and 5,6-dihydro-5-azacytidine. Cancer research, 1977, Volume: 37, Issue:7 Pt 1 Topics: Animals; Azacitidine; Cell Division; Cells, Cultured; Cytidine; Cytidine Deaminase; Deoxycytidine; Drug Synergism; Kinetics; Leukemia L1210; Oxidative Phosphorylation; Tetrahydrouridine; Thymidine; Uridine	1977
Transformation of 5-aza-2'-(3H)deoxycytidine in Escherichia coli. FEBS letters, 1977, Jun-15, Volume: 78, Issue:2 Topics: Azacitidine; Deoxycytidine; Escherichia coli; Tetrahydrouridine; Uracil	1977
Incorporation of a potent antileukemic agent, 5-aza-2'-deoxycytidine, into DNA of cells from leukemic mice. Cancer research, 1977, Volume: 37, Issue:10 Topics: Animals; Azacitidine; Deoxycytidine; Epithelium; Female; Leukemia L1210; Leukemia, Experimental; Liver; Lymph Nodes; Mice; Mice, Inbred AKR; Mice, Inbred BALB C; Mice, Inbred DBA; Precancerous Conditions; Thymidine	1977
Effect of intravenous infusion of 5-aza-2'-deoxycytidine on survival time of mice with L1210 leukemia. Cancer research, 1978, Volume: 38, Issue:9 Topics: Animals; Azacitidine; Cell Survival; Deoxycytidine; In Vitro Techniques; Infusions, Parenteral; Leukemia L1210; Male; Mice; Mice, Inbred Strains; Time Factors	1978
Effects of 5-aza-2'-deoxycytidine on DNA synthesis in mouse lymphatic tissues. Neoplasma, 1978, Volume: 25, Issue:4 Topics: Animals; Azacitidine; Biotransformation; Deoxycytidine; DNA; Female; Mice; Nucleoside-Phosphate Kinase; Spleen; Thymidine; Thymidine Kinase; Thymidine Monophosphate; Thymus Gland	1978
Kinetics of phosphorylation of 5-aza-2'-deoxyycytidine by deoxycytidine kinase. Biochemical pharmacology, 1979, Apr-15, Volume: 28, Issue:8 Topics: Antineoplastic Agents; Azacitidine; Deoxycytidine; Deoxycytidine Kinase; Deoxycytosine Nucleotides; Kinetics; Phosphorylation; Phosphotransferases; Substrate Specificity	1979
Phenotypic conversion of cultured mouse embryo cells by aza pyrimidine nucleosides. Developmental biology, 1978, Volume: 66, Issue:1 Topics: Adenosine Triphosphatases; Animals; Azacitidine; Bungarotoxins; Cell Differentiation; Cell Fusion; Cell Nucleus; Cells, Cultured; Deoxycytidine; DNA; Embryo, Mammalian; Female; Mice; Muscles; Myosins; Nucleoproteins; Phenotype; Pregnancy; Receptors, Cholinergic; RNA	1978
Depression of DNA synthesis in mouse spleen after treatment with 5-aza-2'-deoxycytidine. Journal of the National Cancer Institute, 1979, Volume: 63, Issue:4 Topics: Animals; Azacitidine; Cytidine; Deoxycytidine; DNA; Female; Male; Mice; Nucleoside-Phosphate Kinase; Spleen; Thymidine; Thymidine Monophosphate	1979
Induction of deoxycytidine kinase by 5-azacytidine in an HL-60 cell line resistant to arabinosylcytosine. Molecular pharmacology, 1991, Volume: 39, Issue:2 Topics: Azacitidine; Base Sequence; Cytarabine; Deoxycytidine; Deoxycytidine Kinase; DNA, Neoplasm; Drug Resistance; Enzyme Induction; Humans; Kinetics; Leukemia, Experimental; Leukemia, Myeloid; Methylation; Molecular Sequence Data; Time Factors; Tritium; Tumor Cells, Cultured	1991
5-Azacytidine inhibits the induction of transient TK-deficient cells by 5-bromodeoxyuridine. A novel hypothesis for the facilitation of hypermethylation by 5-bromodeoxyuridine. Mutation research, 1991, Volume: 248, Issue:1 Topics: Azacitidine; Bromodeoxyuridine; Cell Cycle; Chromatography, High Pressure Liquid; Cytidine; Deoxycytidine; DNA; Dose-Response Relationship, Drug; Drug Antagonism; Gene Expression Regulation; Humans; In Vitro Techniques; Methylation; Mutation; Thymidine Kinase	1991
Effect of 5-azacytidine on DNA methylation and the malignant properties of B16 melanoma cells. Cancer research, 1985, Volume: 45, Issue:12 Pt 1 Topics: Animals; Azacitidine; Deoxycytidine; DNA, Neoplasm; Female; Lung Neoplasms; Melanoma; Methylation; Mice; Mice, Inbred C57BL; Neoplasm Metastasis	1985
Levels and stability of DNA methylation in random surviving cell clones derived from a Chinese hamster cell line after prolonged treatment with 5-aza-2'-deoxycytidine. Experimental cell research, 1986, Volume: 162, Issue:1 Topics: Animals; Azacitidine; Cell Cycle; Cell Line; Cell Survival; Clone Cells; Cricetinae; Decitabine; Deoxycytidine; DNA; Female; Methylation; Ovary; Time Factors	1986
Arabinosyl-5-azacytosine: mechanisms of native and acquired resistance. Cancer research, 1986, Volume: 46, Issue:9 Topics: Animals; Azacitidine; Biological Transport; Colonic Neoplasms; Cytidine; Deoxycytidine; Deoxycytidine Kinase; DNA; Drug Resistance; Humans; Leukemia P388; Mice; Phosphorylation	1986
Incorporation of 5-fluorodeoxycytidine and metabolites into nucleic acids of human MCF-7 breast carcinoma cells. Cancer research, 1986, Volume: 46, Issue:9 Topics: Azacitidine; Breast Neoplasms; Cell Line; Cell Survival; Decitabine; Deoxycytidine; Deoxyuridine; DNA, Neoplasm; Floxuridine; Humans; Methylation; RNA, Neoplasm; Tetrahydrouridine	1986
Interaction of deoxycytidine and deoxycytidine analogs in normal and leukemic human myeloid progenitor cells. Leukemia research, 1986, Volume: 10, Issue:9 Topics: Azacitidine; Cell Division; Cell Line; Colony-Forming Units Assay; Cytarabine; Decitabine; Deoxycytidine; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid, Acute	1986
Effect of deoxycytidine on the metabolism and cytotoxicity of 5-aza-2'-deoxycytidine and arabinosyl 5-azacytosine in normal and leukemic human myeloid progenitor cells. Leukemia, 1987, Volume: 1, Issue:12 Topics: Acute Disease; Azacitidine; Bone Marrow; Decitabine; Deoxycytidine; Deoxycytosine Nucleotides; DNA, Neoplasm; Hematopoietic Stem Cells; Humans; Leukemia; Neoplastic Stem Cells	1987
High degree of resistance to 5-aza-2'-deoxycytidine in L1210 cells in vitro associated with almost complete loss of deoxycytidine kinase activity. Neoplasma, 1987, Volume: 34, Issue:6 Topics: 5-Methylcytosine; Animals; Azacitidine; Cell Line; Cells, Cultured; Cytosine; Decitabine; Deoxycytidine; Deoxycytidine Kinase; DNA (Cytosine-5-)-Methyltransferases; Drug Resistance; Leukemia L1210; Mice; Phosphorylation; Phosphotransferases	1987
Genomic 5-methyldeoxycytidine decreases associated with the induction of squamous differentiation in cultured normal human bronchial epithelial cells. Carcinogenesis, 1988, Volume: 9, Issue:12 Topics: Azacitidine; Bronchi; Cell Differentiation; Cells, Cultured; Deoxycytidine; DNA; Epithelium; Humans; Tetradecanoylphorbol Acetate; Transforming Growth Factors	1988
Cellular differentiation, cytidine analogs and DNA methylation. Cell, 1980, Volume: 20, Issue:1 Topics: Adipose Tissue; Animals; Azacitidine; Cell Differentiation; Cells, Cultured; Cytarabine; Cytidine; Decitabine; Deoxycytidine; DNA; DNA (Cytosine-5-)-Methyltransferases; Methylation; Methyltransferases; Mice; Muscles; Structure-Activity Relationship	1980
5-Azacytidine induction of mouse endogenous type C virus and suppression of DNA methylation. Proceedings of the National Academy of Sciences of the United States of America, 1981, Volume: 78, Issue:10 Topics: Animals; Azacitidine; Bromodeoxyuridine; Cell Line; Cytidine; Deoxycytidine; DNA Replication; DNA, Viral; Dose-Response Relationship, Drug; Kinetics; Mice; Mice, Inbred BALB C; Retroviridae; Virus Replication	1981
On the mechanism of inhibition of DNA-cytosine methyltransferases by cytosine analogs. Cell, 1983, Volume: 33, Issue:1 Topics: Azacitidine; Deoxycytidine; DNA; DNA (Cytosine-5-)-Methyltransferases; Methylation; Methyltransferases	1983
Antiproliferative effects and DNA hypomethylation by 5-aza-2'-deoxycytidine in human neuroblastoma cell lines. Anti-cancer drugs, 1993, Volume: 4, Issue:6 Topics: Antigens, Differentiation; Antineoplastic Agents; Azacitidine; Brain Neoplasms; Cell Division; Decitabine; Deoxycytidine; Deoxycytidine Kinase; DNA-Cytosine Methylases; DNA, Neoplasm; Humans; Methylation; Neuroblastoma; Tumor Cells, Cultured	1993
Identification of cytidine deaminase as inhibitor of granulocyte-macrophage colony formation. Experimental hematology, 1994, Volume: 22, Issue:2 Topics: Animals; Azacitidine; Bone Marrow Cells; Cell Division; Cytarabine; Cytidine Deaminase; Deoxycytidine; Deoxyuridine; DNA; Female; Granulocytes; Hematopoietic Stem Cells; Macrophages; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Thymidine	1994
Micronuclei induced by modulators of methylation: analogs of 5-azacytidine. Carcinogenesis, 1995, Volume: 16, Issue:7 Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Deoxycytidine; Leukemia L5178; Methylation; Mice; Mice, Inbred C3H; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mutation	1995
Role of deoxycytidine kinase in an in vitro model for AraC- and DAC-resistance: substrate-enzyme interactions with deoxycytidine, 1-beta-D-arabinofuranosylcytosine and 5-aza-2'-deoxycytidine. Leukemia, 1993, Volume: 7, Issue:7 Topics: Acute Disease; Animals; Antineoplastic Agents; Azacitidine; Binding, Competitive; Cytarabine; Decitabine; Deoxycytidine; Deoxycytidine Kinase; Drug Resistance; In Vitro Techniques; Kinetics; Leukemia, Myeloid; Rats; Rats, Inbred BN; Tumor Cells, Cultured	1993
Studies on the mechanism of action of 1-beta-D-arabinofuranosyl-5-azacytosine (fazarabine) in mammalian lymphoblasts. Journal of experimental therapeutics & oncology, 1996, Volume: 1, Issue:3 Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Cell Survival; Deoxycytidine; DNA, Neoplasm; Humans; Leukemia P388; Lymphocytes; Mice; Mice, Inbred Strains; Phosphorylation; Tumor Cells, Cultured	1996
Drug resistance to 5-aza-2'-deoxycytidine, 2',2'-difluorodeoxycytidine, and cytosine arabinoside conferred by retroviral-mediated transfer of human cytidine deaminase cDNA into murine cells. Cancer chemotherapy and pharmacology, 1998, Volume: 42, Issue:5 Topics: 3T3 Cells; Animals; Antimetabolites; Antimetabolites, Antineoplastic; Azacitidine; Colony-Forming Units Assay; Cytarabine; Cytidine Deaminase; Decitabine; Deoxycytidine; DNA, Complementary; Drug Resistance; Enzyme Inhibitors; Fibroblasts; Gemcitabine; Gene Transfer Techniques; Genetic Vectors; Humans; Mice; Phenotype; Retroviridae; Tetrahydrouridine	1998
Activation of the maternally preset program of apoptosis by microinjection of 5-aza-2'-deoxycytidine and 5-methyl-2'-deoxycytidine-5'-triphosphate in Xenopus laevis embryos. Development, growth & differentiation, 2001, Volume: 43, Issue:4 Topics: Animals; Apoptosis; Azacitidine; Decitabine; Deoxycytidine; DNA Fragmentation; DNA Methylation; DNA Modification Methylases; Embryo, Nonmammalian; Female; In Situ Nick-End Labeling; Microinjections; Oocytes; Proto-Oncogene Proteins c-bcl-2; Xenopus laevis	2001
Selection of drug-resistant transduced cells with cytosine nucleoside analogs using the human cytidine deaminase gene. Cancer gene therapy, 2001, Volume: 8, Issue:9 Topics: Antimetabolites, Antineoplastic; Azacitidine; Bone Marrow Cells; Colony-Forming Units Assay; Cytarabine; Cytidine Deaminase; Decitabine; Deoxycytidine; DNA Modification Methylases; Drug Evaluation; Drug Resistance; Enzyme Inhibitors; Flow Cytometry; Gene Transfer Techniques; Genetic Vectors; Green Fluorescent Proteins; Humans; Leukemia; Luminescent Proteins; Retroviridae; Transgenes	2001
Cytotoxic activity of 2',2'-difluorodeoxycytidine, 5-aza-2'-deoxycytidine and cytosine arabinoside in cells transduced with deoxycytidine kinase gene. Biochemical and biophysical research communications, 2002, May-24, Volume: 293, Issue:5 Topics: 3T3 Cells; Animals; Azacitidine; Cell Death; Cell Line; Cytarabine; Cytidine Deaminase; Decitabine; Deoxycytidine; Deoxycytidine Kinase; DNA, Complementary; Dose-Response Relationship, Drug; Gemcitabine; Genetic Vectors; Humans; Mice; Phenotype; Phosphorylation; Retroviridae; Thymidine Kinase; Tumor Cells, Cultured	2002
Growth delay of human pancreatic cancer cells by methylase inhibitor 5-aza-2'-deoxycytidine treatment is associated with activation of the interferon signalling pathway. Oncogene, 2005, Jan-06, Volume: 24, Issue:1 Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Azacitidine; Cisplatin; Decitabine; Deoxycytidine; DNA Methylation; DNA Modification Methylases; Gemcitabine; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Interferon-gamma; Interferons; Pancreatic Neoplasms; Signal Transduction	2005
Interleukin 6 supports the maintenance of p53 tumor suppressor gene promoter methylation. Cancer research, 2005, Jun-01, Volume: 65, Issue:11 Topics: Apoptosis; Azacitidine; Base Sequence; Cell Cycle; Cell Line, Tumor; Cytidine; Decitabine; Deoxycytidine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Gene Silencing; Genes, p53; Humans; Interleukin-6; Molecular Sequence Data; Multiple Myeloma; Promoter Regions, Genetic; Sulfites; Tumor Suppressor Protein p53	2005
Comparison of biological effects of non-nucleoside DNA methylation inhibitors versus 5-aza-2'-deoxycytidine. Molecular cancer therapeutics, 2005, Volume: 4, Issue:10 Topics: Antimetabolites, Antineoplastic; Azacitidine; Carcinoma, Transitional Cell; Catechin; Cell Line, Tumor; Colorectal Neoplasms; Cytidine; Decitabine; Deoxycytidine; DNA Methylation; DNA Modification Methylases; Enzyme Inhibitors; Female; Gene Silencing; HT29 Cells; Humans; Hydralazine; Male; Procainamide; Prostatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction	2005
Characterization of in vitro and in vivo hypomethylating effects of decitabine in acute myeloid leukemia by a rapid, specific and sensitive LC-MS/MS method. Nucleic acids research, 2007, Volume: 35, Issue:5 Topics: Acute Disease; Antimetabolites, Antineoplastic; Azacitidine; Cell Line, Tumor; Chromatography, Liquid; Clinical Trials, Phase I as Topic; Decitabine; Deoxycytidine; Deoxyguanosine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Humans; Leukemia, Myeloid; Tandem Mass Spectrometry	2007
Global genomic methylation levels in the liver and gonads of the three-spine stickleback (Gasterosteus aculeatus) after exposure to hexabromocyclododecane and 17-beta oestradiol. Environment international, 2008, Volume: 34, Issue:3 Topics: Animals; Azacitidine; Carcinogens; Decitabine; Deoxycytidine; DNA; Estradiol; Female; Gonads; Hydrocarbons, Brominated; Liver; Male; Methylation; Smegmamorpha	2008
The high rate of endoreduplication in the repair deficient CHO mutant EM9 parallels a reduced level of methylated deoxycytidine in DNA. Mutation research, 2008, Sep-26, Volume: 644, Issue:1-2 Topics: Animals; Azacitidine; CHO Cells; Chromosomes; Cricetinae; Cricetulus; Deoxycytidine; DNA Methylation; DNA Repair; DNA Replication; Mutation	2008
Role of myofibroblasts in innate chemoresistance of pancreatic carcinoma--epigenetic downregulation of caspases. International journal of cancer, 2008, Oct-15, Volume: 123, Issue:8 Topics: Animals; Apoptosis; Azacitidine; Carcinoma, Pancreatic Ductal; Caspases; Cell Line, Tumor; Cell Nucleus; Coculture Techniques; Decitabine; Deoxycytidine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; Down-Regulation; Drug Resistance, Neoplasm; Epigenesis, Genetic; Etoposide; Female; Fibroblasts; Gemcitabine; Humans; Mice; Mice, SCID; Pancreatic Neoplasms; STAT1 Transcription Factor; Transfection	2008
Methyl-CpG targeted transcriptional activation allows re-expression of tumor suppressor genes in human cancer cells. Biochemical and biophysical research communications, 2008, Dec-12, Volume: 377, Issue:2 Topics: Adaptor Proteins, Signal Transducing; Azacitidine; Base Sequence; Cell Line, Tumor; CpG Islands; Deoxycytidine; DNA Methylation; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Tumor Suppressor; Humans; Molecular Sequence Data; MutL Protein Homolog 1; NF-kappa B; Nuclear Proteins; Oligonucleotide Array Sequence Analysis; Promoter Regions, Genetic; Transcriptional Activation	2008
Quantification of regional DNA methylation by liquid chromatography/tandem mass spectrometry. Analytical biochemistry, 2009, Aug-15, Volume: 391, Issue:2 Topics: Azacitidine; Base Sequence; Cell Line, Tumor; Chromatography, High Pressure Liquid; Decitabine; Deoxycytidine; DNA; DNA Methylation; Humans; Promoter Regions, Genetic; Reproducibility of Results; Tandem Mass Spectrometry	2009
Use of Drosophila deoxynucleoside kinase to study mechanism of toxicity and mutagenicity of deoxycytidine analogs in Escherichia coli. DNA repair, 2010, Feb-04, Volume: 9, Issue:2 Topics: Animals; Antineoplastic Agents; Azacitidine; Cytidine; Deoxycytidine; DNA; DNA Methylation; DNA Mismatch Repair; Drosophila melanogaster; Escherichia coli; Fluorescence; Microbial Sensitivity Tests; Mutagenesis; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor)	2010
Up-regulation of connexin 32 gene by 5-aza-2'-deoxycytidine enhances vinblastine-induced cytotoxicity in human renal carcinoma cells via the activation of JNK signalling. Biochemical pharmacology, 2010, Aug-15, Volume: 80, Issue:4 Topics: Azacitidine; Carcinoma, Renal Cell; Cell Proliferation; Connexins; Decitabine; Deoxycytidine; Down-Regulation; Enzyme Activation; Gap Junction beta-1 Protein; Gene Expression Regulation, Neoplastic; Humans; JNK Mitogen-Activated Protein Kinases; Kidney Neoplasms; Signal Transduction; Transcriptional Activation; Up-Regulation; Vinblastine	2010
Exploiting drug repositioning for discovery of a novel HIV combination therapy. Journal of virology, 2010, Volume: 84, Issue:18 Topics: Anti-HIV Agents; Azacitidine; Decitabine; Deoxycytidine; Drug Interactions; Drug Therapy, Combination; Gemcitabine; HIV; HIV Infections; Humans; Mutation	2010
Fused-core silica column ultra-performance liquid chromatography-ion trap tandem mass spectrometry for determination of global DNA methylation status. Analytical biochemistry, 2011, Feb-01, Volume: 409, Issue:1 Topics: Azacitidine; Cell Line, Tumor; Chromatography, High Pressure Liquid; Decitabine; Deoxycytidine; Deoxyguanosine; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Enzyme Inhibitors; Humans; Silicon Dioxide; Tandem Mass Spectrometry	2011
Methylation-mediated silencing of TMS1 in pancreatic cancer and its potential contribution to chemosensitivity. Anticancer research, 2010, Volume: 30, Issue:10 Topics: Antineoplastic Combined Chemotherapy Protocols; Azacitidine; CARD Signaling Adaptor Proteins; Cell Line, Tumor; Cytoskeletal Proteins; Deoxycytidine; DNA Methylation; Docetaxel; Drug Resistance, Neoplasm; Drug Synergism; Gemcitabine; Gene Silencing; Humans; Pancreatic Neoplasms; Promoter Regions, Genetic; Taxoids; Transfection	2010
Ultra-performance liquid chromatography/tandem mass spectrometry for accurate quantification of global DNA methylation in human sperms. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2011, Jun-01, Volume: 879, Issue:19 Topics: Azacitidine; Chromatography, High Pressure Liquid; Decitabine; Deoxycytidine; Deoxyguanosine; DNA; DNA Methylation; Hep G2 Cells; Humans; Male; Reproducibility of Results; Sensitivity and Specificity; Spermatozoa; Tandem Mass Spectrometry	2011
Discovery of drugs that possess activity against feline leukemia virus. The Journal of general virology, 2012, Volume: 93, Issue:Pt 4 Topics: Adenine; Animals; Antiviral Agents; Azacitidine; Cat Diseases; Cats; Decitabine; Deoxycytidine; Dose-Response Relationship, Drug; Gemcitabine; Leukemia Virus, Feline; Leukemia, Feline; Organophosphonates; Pyrrolidinones; Raltegravir Potassium; Retroviridae Infections; Tenofovir; Tumor Virus Infections	2012
Activity of a novel combined antiretroviral therapy of gemcitabine and decitabine in a mouse model for HIV-1. Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:4 Topics: Animals; Anti-HIV Agents; Azacitidine; Body Weight; Cells, Cultured; Chemical and Drug Induced Liver Injury; Decitabine; Deoxycytidine; Drug Combinations; Drug Synergism; Female; Flow Cytometry; Gemcitabine; HIV-1; Humans; Liver; Lymph Nodes; Mice; Mice, Inbred C57BL; Murine Acquired Immunodeficiency Syndrome; Proviruses; Spleen; T-Lymphocytes; Transfection	2012
Role of human nucleoside transporters in the uptake and cytotoxicity of azacitidine and decitabine. Nucleosides, nucleotides & nucleic acids, 2012, Volume: 31, Issue:3 Topics: Animals; Azacitidine; Carbon Radioisotopes; Decitabine; Deoxycytidine; Equilibrative Nucleoside Transporter 1; Gemcitabine; Humans; Membrane Transport Proteins; Oocytes; Saccharomyces cerevisiae; Tritium; Xenopus	2012
Epigenetic modifiers enhance the synergistic cytotoxicity of combined nucleoside analog-DNA alkylating agents in lymphoma cell lines. Experimental hematology, 2012, Volume: 40, Issue:10 Topics: Antineoplastic Agents, Alkylating; Ataxia Telangiectasia Mutated Proteins; Azacitidine; Busulfan; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Checkpoint Kinase 2; Cytotoxins; Decitabine; Deoxycytidine; DNA (Cytosine-5-)-Methyltransferases; DNA Methyltransferase 3A; DNA Methyltransferase 3B; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Drug Synergism; Epigenesis, Genetic; Gemcitabine; Hematopoietic Stem Cell Transplantation; Humans; Hydroxamic Acids; Lymphoma; Melphalan; Protein Serine-Threonine Kinases; Transplantation Conditioning; Transplantation, Homologous; Tumor Suppressor Proteins	2012
Targeting the MAGE A3 antigen in pancreatic cancer. Surgery, 2012, Volume: 152, Issue:3 Suppl 1 Topics: Adenocarcinoma; Antigens, Neoplasm; Azacitidine; Cell Line, Tumor; Chromatin Assembly and Disassembly; Cytokines; Decitabine; Deoxycytidine; DNA Methylation; Gemcitabine; Humans; Hydroxamic Acids; Immunotherapy; Male; Neoplasm Proteins; Pancreas; Pancreatic Neoplasms; Receptors, Antigen, T-Cell; T-Lymphocytes; Testis; Valproic Acid	2012
Gemcitabine reactivates epigenetically silenced genes and functions as a DNA methyltransferase inhibitor. International journal of molecular medicine, 2012, Volume: 30, Issue:6 Topics: Antimetabolites, Antineoplastic; Azacitidine; Cell Line, Tumor; CpG Islands; Decitabine; Deoxycytidine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Enzyme Stability; Epigenesis, Genetic; Gemcitabine; Gene Expression Regulation, Neoplastic; Gene Silencing; Histone Deacetylase 1; Humans; Promoter Regions, Genetic; Tumor Suppressor Proteins; Vascular Endothelial Growth Factor Receptor-1	2012
Characterization of permeability, stability and anti-HIV-1 activity of decitabine and gemcitabine divalerate prodrugs. Antiviral chemistry & chemotherapy, 2014, Dec-16, Volume: 23, Issue:6 Topics: Anti-HIV Agents; Azacitidine; Biological Availability; Caco-2 Cells; Cell Proliferation; Decitabine; Deoxycytidine; Drug Stability; Gemcitabine; Half-Life; HEK293 Cells; HIV-1; Humans; Hydrogen-Ion Concentration; Permeability; Prodrugs	2014
Aza-deoxycytidine induces apoptosis or differentiation via DNMT3B and targets embryonal carcinoma cells but not their differentiated derivatives. British journal of cancer, 2014, Apr-15, Volume: 110, Issue:8 Topics: Apoptosis; Azacitidine; Cell Differentiation; Deoxycytidine; DNA (Cytosine-5-)-Methyltransferases; DNA Methyltransferase 3B; Embryonal Carcinoma Stem Cells; Humans; Pluripotent Stem Cells; Stem Cells; Teratocarcinoma	2014
Novel DNA methyltransferase-1 (DNMT1) depleting anticancer nucleosides, 4'-thio-2'-deoxycytidine and 5-aza-4'-thio-2'-deoxycytidine. Cancer chemotherapy and pharmacology, 2014, Volume: 74, Issue:2 Topics: Animals; Azacitidine; Blotting, Western; Cell Proliferation; Deoxycytidine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA, Neoplasm; Female; Humans; Mice; Mice, Nude; Neoplasms, Experimental; Real-Time Polymerase Chain Reaction; Thionucleosides; Tumor Cells, Cultured	2014
Tautomerism provides a molecular explanation for the mutagenic properties of the anti-HIV nucleoside 5-aza-5,6-dihydro-2'-deoxycytidine. Proceedings of the National Academy of Sciences of the United States of America, 2014, Aug-12, Volume: 111, Issue:32 Topics: Anti-HIV Agents; Azacitidine; Bacteriophage M13; Base Pairing; Deoxycytidine; Genome, Viral; HIV; Humans; Isomerism; Magnetic Resonance Spectroscopy; Models, Chemical; Mutagens; Spectrophotometry, Infrared; Virus Replication	2014
Trace analysis of methylated and hydroxymethylated cytosines in DNA by isotope-dilution LC-MS/MS: first evidence of DNA methylation in Caenorhabditis elegans. The Biochemical journal, 2015, Jan-01, Volume: 465, Issue:1 Topics: 5-Methylcytosine; Animals; Azacitidine; Cadmium; Caenorhabditis elegans; Chromatography, Liquid; Cytosine; Decitabine; Deoxycytidine; DNA; DNA Methylation; Isotope Labeling; Online Systems; Reproducibility of Results; Solid Phase Extraction; Tandem Mass Spectrometry	2015
Lethal toxicity after administration of azacytidine: implication of the cytidine deaminase-deficiency syndrome. Pharmacogenetics and genomics, 2015, Volume: 25, Issue:6 Topics: Antimetabolites, Antineoplastic; Azacitidine; Cytarabine; Cytidine Deaminase; Deoxycytidine; Fatal Outcome; Gemcitabine; Humans; Inactivation, Metabolic; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Polymorphism, Single Nucleotide	2015
Gemcitabine enhances rituximab-mediated complement-dependent cytotoxicity to B cell lymphoma by CD20 upregulation. Cancer science, 2016, Volume: 107, Issue:5 Topics: Antigens, CD20; Azacitidine; Cell Line, Tumor; Complement System Proteins; Cytotoxicity, Immunologic; Deoxycytidine; Gemcitabine; Humans; Lenalidomide; Lymphoma, B-Cell; Lymphoma, Large B-Cell, Diffuse; NF-kappa B; Rituximab; Thalidomide; Up-Regulation	2016
Double epigenetic modulation of high-dose chemotherapy with azacitidine and vorinostat for patients with refractory or poor-risk relapsed lymphoma. Cancer, 2016, 09-01, Volume: 122, Issue:17 Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Busulfan; Child; Deoxycytidine; Drug Resistance, Neoplasm; Epigenesis, Genetic; Female; Follow-Up Studies; Gemcitabine; Humans; Hydroxamic Acids; Lymphoma; Male; Melphalan; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Prognosis; Survival Rate; Vorinostat; Young Adult	2016
Genotoxicity kinetics in murine normoblasts as an approach for the in vivo action of difluorodeoxycytidine. Cancer chemotherapy and pharmacology, 2017, Volume: 79, Issue:5 Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Cell Survival; Deoxycytidine; DNA Damage; Dose-Response Relationship, Drug; Erythroblasts; Erythrocytes; Gemcitabine; Kinetics; Male; Mice; Mice, Inbred BALB C; Micronucleus Tests; Mutagens	2017
Monophosphorylation by deoxycytidine kinase affects apparent cellular uptake of decitabine in HCT116 colon cancer cells. Drug metabolism and pharmacokinetics, 2017, Volume: 32, Issue:6 Topics: Antimetabolites, Antineoplastic; Azacitidine; Camptothecin; Colonic Neoplasms; Cytarabine; Decitabine; Deoxycytidine; Deoxycytidine Kinase; Equilibrative Nucleoside Transporter 1; Etoposide; Gemcitabine; HCT116 Cells; Humans; Irinotecan; Phosphorylation	2017
[The Relationship of Clinicopathology of p16 in Non-small Cell Lung Cancer and 5-nitrogen impurity-2'-deoxycytidine-nitrogen Impurity on the Influence of p16 Expression in Lung Cancer A549 Cells]. Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2018, Volume: 49, Issue:3 Topics: A549 Cells; Azacitidine; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p16; Deoxycytidine; DNA Methylation; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Promoter Regions, Genetic	2018
Development, validation, and clinical application of a high-performance liquid chromatography-tandem mass spectrometry assay for the quantification of total intracellular β-decitabine nucleotides and genomic DNA incorporated β-decitabine and 5-methyl-2'-d Journal of pharmaceutical and biomedical analysis, 2019, Feb-05, Volume: 164 Topics: Adult; Antimetabolites, Antineoplastic; Azacitidine; Chromatography, High Pressure Liquid; Clinical Trials, Phase II as Topic; Decitabine; Deoxycytidine; DNA; DNA Methylation; Humans; Leukocytes, Mononuclear; Limit of Detection; Neoplasms; Randomized Controlled Trials as Topic; Tandem Mass Spectrometry	2019
The Effect of 5-aza,2'-deoxyCytidine (5 AZA CdR or Decitabine) on Extrinsic, Intrinsic, and JAK/STAT Pathways in Neuroblastoma and Glioblastoma Cells Lines. Asian Pacific journal of cancer prevention : APJCP, 2023, Jun-01, Volume: 24, Issue:6 Topics: Azacitidine; Cell Line; Cell Line, Tumor; Decitabine; Deoxycytidine; DNA Methylation; Glioblastoma; Humans; Janus Kinases; Neuroblastoma; Signal Transduction; STAT Transcription Factors	2023