azacitidine has been researched along with cytosine in 142 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 43 (30.28) | 18.7374 |
| 1990's | 32 (22.54) | 18.2507 |
| 2000's | 33 (23.24) | 29.6817 |
| 2010's | 33 (23.24) | 24.3611 |
| 2020's | 1 (0.70) | 2.80 |
| Authors | Studies |
|---|---|
| Anderson, JE; Giblett, ER; Teng, YS | 1 |
| Hradecna, Z; Jacob, HE; Kittler, L; Löber, G | 1 |
| Hayashibara, KC; Verdine, GL | 1 |
| Matsuda, M; Yasutomi, M | 1 |
| Gartler, SM; Hansen, RS | 1 |
| Lutze, LH; Morgan, WF; Phillips, JW; Winegar, RA | 1 |
| Cosgrove, DE; Cox, GS | 1 |
| Kuipers, AG; Mooibroek, H; Punt, PJ; Sietsma, JH; Wessels, JG | 1 |
| Bona, R; Cozzi, R; D'Erme, M; Palitti, F; Perticone, P | 1 |
| Storch, TG | 1 |
| Catravas, GN; Kalinich, JF; Snyder, SL | 1 |
| Kurosawa, T; Ookawara, T; Sugiyama, T; Suzuki, K; Taniguchi, N | 1 |
| Chalkley, R; Faber, S; Granner, D; Ip, T | 1 |
| Nyce, J | 1 |
| Selker, EU; Stevens, JN | 1 |
| Cihák, A; Cízková, J; Korbová, L; Kucerová, V; Pískala, A | 1 |
| Jones, PA; Kautiainen, TL | 1 |
| Haaf, T; Ott, G; Scheres, JM; Schmid, M; Wensing, JA | 1 |
| Everett, CA; Finch, M; Hart, IR; Ormerod, EJ | 1 |
| Holliday, R | 1 |
| Fairweather, DS; Fox, M; Margison, GP | 1 |
| Fujii, N; Oguma, K | 1 |
| Frahm, J; Hoshino, J; Kröger, H | 1 |
| Gunter, KC; Sneller, MC | 1 |
| Heuertz, S; Homman, N; Hors-Cayla, MC | 1 |
| Jones, PA; Michalowsky, LA | 2 |
| Bianchi, MS; Bianchi, NO; Larramendy, M | 1 |
| Veselý, J | 1 |
| Isham, KR; Kenney, FT; Lee, KL; Rothrock, R | 1 |
| Fioretti, MC; Fuschiotti, P; Puccetti, P; Romani, L | 1 |
| Cecchini, E; Citti, L; Durante, M; Geri, C; Natali, L; Nuti Ronchi, V; Parenti, R | 1 |
| Farooq, M; Holliday, R; Hunter, JL; Matsumura, T | 1 |
| Chandler, LA; Jones, PA | 1 |
| Korba, BE; Wilson, VL; Yoakum, GH | 1 |
| Kittler, L | 1 |
| Ikushima, T | 1 |
| Maharajan, V; Pratibha, M; Scarano, E; Tosi, L | 1 |
| Bird, S; Cowing, D; Gusella, J; Hoffmann, JW; Steffen, D; Tabin, C; Weinberg, RA | 1 |
| Adams, RL; Burdon, RH | 1 |
| Adams, JK; Allan, RG; Cooper, IA; Woodcock, DM | 1 |
| Harris, JS; Lu, LJ; Randerath, K; Tseng, WC | 1 |
| Bouchard, J; Chabot, GG; Momparler, RL | 1 |
| Jones, PA; Momparler, RL; Wilson, VL | 1 |
| Cooper, DN | 1 |
| Faraggi, M; Riesz, P; Rosenthal, I | 1 |
| Jones, PA; Riggs, AD | 1 |
| Clarke, LE; Hepburn, AG; Pearson, L; White, J | 1 |
| Jones, PA; Taylor, SM; Wilson, V | 1 |
| Constantinides, PA; Jones, PA; Taylor, SM | 1 |
| Christman, JK | 1 |
| Donaghue, TP; Frost, P; Kerbel, RS; Liteplo, RG | 1 |
| Chiswell, DJ; Gillespie, DA; Searle, S; Wyke, JA | 1 |
| Flatau, E; Gonzales, FA; Jones, PA; Michalowsky, LA | 1 |
| Strobl, JS; Thompson, EB | 1 |
| Claeys, KM; Foss, HM; Roberts, CJ; Selker, EU | 1 |
| Hsieh, CL | 1 |
| Cashman, NR; Ledoux, S; Nalbantoglu, J | 1 |
| Campos, A; Fernández, JL; Gosálvez, J; Goyanes, V; Pereira, S | 1 |
| Baylin, SB; Davidson, NE; Ferguson, AT; Lapidus, RG | 1 |
| Baylin, SB; Burger, PC; Gabrielson, E; Herman, JG; Lee, DJ; Mao, L; Merlo, A; Sidransky, D | 1 |
| Pinney, RJ; Radnedge, L | 1 |
| Chalasani, S; Dy, L; Essani, K | 1 |
| de Capoa, A; Di Leandro, M; Giancotti, P; Grappelli, C; Marotta, MR; Menendez, F; Niveleau, A; Poggesi, I; Reynaud, C | 1 |
| Bird, AP | 1 |
| Irelan, JT; Selker, EU | 1 |
| Jääskeläinen, T; Mäenpää, PH; Pirskanen, A; Ryhänen, S | 1 |
| Chen, ZJ; Pikaard, CS | 1 |
| Buchholz, WG; Hall, TC; Kumpatla, SP; Teng, W | 1 |
| Bezdek, M; Egertová, M; Gazdova, B; Glyn, MC; Kovarik, A; Leitch, AR | 1 |
| Christiansen-Weber, T; Haas, M; Haggblom, C; Vogt, M; Yeargin, J | 1 |
| Allaman-Pillet, N; Bonny, C; Djemaï, A; Schorderet, DF | 1 |
| Côté, S; Momparler, RL; Sinnett, D | 1 |
| Castilho, A; Heslop-Harrison, JS; Neves, N; Rufini-Castiglione, M; Viegas, W | 1 |
| Depicker, A; Holý, A; Kovarík, A; Van Houdt, H | 1 |
| Jones, PA; Robertson, KD | 1 |
| Bearzatto, A; Jiricny, J; Karran, P; Macpherson, P; Szadkowski, M | 1 |
| Benoit, G; Doerksen, T; Trasler, JM | 1 |
| Cao, YX; Jean, JC; Williams, MC | 1 |
| Borniquel, S; Callejas, S; Gutiérrez, JC; Martín-González, A | 1 |
| Bashambu, M; Singal, R; van Wert, J | 1 |
| Carter, KB; Cauthron, RD; Gan, J; Steinberg, RA; Zhang, YL | 1 |
| Fujita, M; Hosokawa, M; Imai, K; Itoh, F; Kikuchi, T; Suzuki, H; Toyota, M; Yamamoto, H | 1 |
| Czyz, M; Fabianowska-Majewska, K; Wyczechowska, D | 1 |
| Giles, FJ | 2 |
| Mathieu, O; Picard, G; Sugiura, M; Tourmente, S; Yukawa, Y | 1 |
| Comai, L; Davison, J; Madlung, A; Masuelli, RW; Reynolds, SH; Watson, B | 1 |
| Bertoni, F; Cotter, FE; Fu, WN; Jia, L; Kelsey, SM; McElwaine, SM; Newland, AC | 1 |
| Avila, S; Esteller, M; Fraga, MF; Guo, M; Herman, JG; Paz, MF; Pollan, M | 1 |
| Kumar, PP; Kush, A; Lakshmanan, P; Prakash, AP | 1 |
| Domann, FE; Futscher, BW; Junk, DJ; Munoz-Rodriguez, JL; Oshiro, MM; Watts, GS; Wozniak, RJ | 1 |
| Bhakat, KK; Mitra, S | 1 |
| Baylin, SB; Belinsky, SA; Herman, JG; Issa, JP; Klinge, DM; March, TH; Stidley, CA | 1 |
| Chow, BK; Lee, LT; Ng, SS; Pang, RT; Yung, WH | 1 |
| Cappellacci, L; Montgomery, JA; Secrist, JA; Tiwari, KN | 1 |
| Dong, YZ; Fedak, G; Han, FP; Hao, S; Liu, B; Liu, ZL; Shan, XH; Tan, M; Wang, XZ | 1 |
| Cockerell, GL; Goodman, JI; McKim, JM; Watson, RE | 1 |
| Aoyama, T; Ishibe, T; Nagayama, S; Nakamura, T; Nakayama, T; Nishijo, K; Okamoto, T; Toguchida, J; Yasura, K | 1 |
| Butler, JS; Ladd, PD; Skalnik, DG | 1 |
| Brown, JC; Fieldes, MA; Krech, MJ; Schaeffer, SM | 1 |
| Law, RD; Suttle, JC | 1 |
| Akintola, AD; Burghardt, RC; Catania, JM; Chen, G; Crislip, ZL; Parrish, AR; Zimmer, WE | 1 |
| Bokelmann, I; Lyko, F; Mahlknecht, U; Stresemann, C | 1 |
| Wang, H; Wang, Y | 1 |
| Bosque, A; Kauder, SE; Lindqvist, A; Planelles, V; Verdin, E | 1 |
| Bettuzzi, S; Patra, SK | 1 |
| Carambula, SF; Hansen, PJ; Oliveira, LJ | 1 |
| Jagodzinski, PP; Lianeri, M; Lutkowska, A; Pietkiewicz, PP | 1 |
| Huang, X; Wang, X; Yin, J; Zhong, J | 1 |
| Dyk, Ev; Gouws, C; Huysamen, C; Koekemoer, G; Pretorius, PJ; Wentzel, JF | 1 |
| Farkas, DL; Gertych, A; Tajbakhsh, J | 1 |
| Czemerska, M; Grzybowska-Izydorczyk, O; Pluta, A; Robak, T; Szmigielska-Kapłon, A; Wierzbowska, A; Wolska, A | 1 |
| Baer, MR; Gojo, I | 1 |
| Gutierrez, JA; Hemeon, I; Ho, MC; Schramm, VL | 1 |
| Bao, B; Rodriguez-Melendez, R; Zempleni, J | 1 |
| Kou, H; Li, Y; Lin, X; Liu, B; Wang, D; Wu, Y; Xia, Q; Xing, S; Xu, C | 1 |
| Jabbour, E; Kadia, TM; Kantarjian, H | 1 |
| Choi, EY; Lee, MA; Park, MJ; Yang, JW | 1 |
| Arànyi, T; Bacquet, C; Páldi, A; Szabó, P; Szüts, D; Yamagata, Y | 1 |
| Asurmendi, S; Marfil, CF; Masuelli, RW | 1 |
| Krečmerová, M; Otmar, M | 1 |
| Ji, D; Li, Q; Li, S; Song, Y; Wang, P; Xiang, F | 1 |
| Bracht, JR; Landweber, LF; Perlman, DH | 1 |
| Karetin, YA; Kiselev, KV; Tyunin, AP | 1 |
| Kone, BC; Kong, Q; Yu, Z | 1 |
| Cho, IH; Chowdhury, B; Cui, Y; Irudayaraj, J | 1 |
| Iliakis, G; Moscariello, M | 1 |
| Mandarano, AH; Militello, KT; Simon, RD; Varechtchouk, O | 1 |
| Cairns, BR; Khoddami, V | 1 |
| Dolan, ME; Godley, LA; Moen, EL; Stark, AL; Zhang, W | 1 |
| Huang, Y; Rao, A | 1 |
| Sakata-Yanagimoto, M | 1 |
| Chao, MR; Chen, JL; Hsu, YW; Hu, CW; Yen, CC | 1 |
| Chevassut, T; Cho, IH; Choudhury, SR; Chowdhury, B; Cooper, B; Cui, Y; Irudayaraj, J; Lossie, AC; McGovern, A | 1 |
| DeSimone, J; Ibanez, V; Lavelle, D; Mahmud, N; Rivers, A; Ruiz, MA; Vaitkus, K | 1 |
| Cantatore, S; DiNatale, A; Hennick, SM; Lazatin, JC; Mandarano, AH; Militello, KT; Simon, RD | 1 |
| Levine, AJ | 1 |
| Cummings-Lorbetskie, C; Desaulniers, D; Parfett, C; Xiao, GH; Zhou, G | 1 |
| Chen, L; He, C; Jiang, S; Peng, H; Wei, H; Wu, S | 1 |
| Chen, G; Chen, H; Dong, Z; Liu, H; Liu, Y; Ren, S; Sun, L; Tang, L; Xia, M; Zhang, L; Zhu, J | 1 |
| Bai, C; Cheng, G; Li, C; Yang, W; Zhuang, J | 1 |
19 review(s) available for azacitidine and cytosine
| Article | Year |
|---|---|
Hypomethylation of DNA in the regulation of gene expression.
Topics: 5-Methylcytosine; Animals; Azacitidine; Cell Differentiation; Cytosine; DNA; Gene Expression Regulation; Humans; Methylation; Methyltransferases; Neoplasms | 1988 |
DNA methylation in eukaryotes.
Topics: 5-Methylcytosine; Aging; Animals; Azacitidine; Base Sequence; Chromatin; Cytosine; Deoxyribonuclease HpaII; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA Restriction Enzymes; DNA-Cytosine Methylases; Gene Expression Regulation; Globins; Methylation; Nucleic Acid Conformation; Ovalbumin | 1982 |
Eukaryotic DNA methylation.
Topics: 5-Methylcytosine; Animals; Azacitidine; Base Composition; Cell Differentiation; Chromosome Mapping; Cytosine; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA Repair; DNA Replication; Eukaryotic Cells; Gene Expression Regulation; Genes; Genes, Viral; Humans; Methylation; Models, Genetic; Mutation; Transcription, Genetic; Transformation, Genetic | 1983 |
5-methylcytosine, gene regulation, and cancer.
Topics: 5-Methylcytosine; Animals; Azacitidine; Base Sequence; Carcinogens; Cell Transformation, Neoplastic; Cytosine; DNA (Cytosine-5-)-Methyltransferases; DNA Replication; Fibroblasts; Gene Expression Regulation; Humans; Models, Biological; Muscles; Neoplasms; Oncogenes | 1983 |
DNA modification, differentiation, and transformation.
Topics: 5-Methylcytosine; Animals; Azacitidine; Carcinogens; Cell Differentiation; Cell Line; Cell Survival; Cricetinae; Cricetulus; Cytosine; DNA; DNA (Cytosine-5-)-Methyltransferases; Fibroblasts; Humans; Methylation; Mice; Papio; Phenotype; Rats; Transformation, Genetic | 1983 |
5-Azacytidine, DNA methylation, and differentiation.
Topics: 5-Methylcytosine; Azacitidine; Cell Differentiation; Cytidine; Cytosine; DNA; DNA (Cytosine-5-)-Methyltransferases; Dosage Compensation, Genetic; Female; Gene Expression Regulation; Genes, Viral; Methylation; Methyltransferases; Nucleic Acids; Phosphorylation; RNA, Transfer; X Chromosome | 1984 |
DNA methylation in friend erythroleukemia cells: the effects of chemically induced differentiation and of treatment with inhibitors of DNA methylation.
Topics: 5-Methylcytosine; Animals; Azacitidine; Cell Differentiation; Cell Line; Cytosine; Decitabine; DNA (Cytosine-5-)-Methyltransferases; DNA, Neoplasm; Friend murine leukemia virus; Gene Expression Regulation; Globins; Leukemia, Erythroblastic, Acute; Methylation; Mice | 1984 |
The relationship of DNA methylation to cancer.
Topics: 5-Methylcytosine; Azacitidine; CpG Islands; Cytosine; Decitabine; DNA Methylation; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Methyltransferases; Neoplasms | 1996 |
DNA methylation: past, present and future directions.
Topics: 5-Methylcytosine; Antimetabolites, Antineoplastic; Azacitidine; Carcinogens; Chromatin; Cytosine; DNA Methylation; DNA Repair; Forecasting; Gene Expression; Humans; Neoplasms | 2000 |
DNA methylation in ciliates: implications in differentiation processes.
Topics: 5-Methylcytosine; Adenine; Animals; Azacitidine; Cell Differentiation; Cell Nucleus; Ciliophora; Cytosine; DNA Methylation; DNA Modification Methylases; DNA, Protozoan; Gene Expression Regulation; Gene Expression Regulation, Developmental; Paramecium; Protozoan Proteins; Tetrahymena | 2000 |
Novel agents for the therapy of acute leukemia.
Topics: Angiogenesis Inhibitors; Antineoplastic Agents; Azacitidine; Cysteine Endopeptidases; Cytosine; Decitabine; Dioxolanes; DNA Methylation; Humans; Leukemia; Multienzyme Complexes; Neovascularization, Pathologic; Proteasome Endopeptidase Complex | 2002 |
New drugs in acute myeloid leukemia.
Topics: Acute Disease; Adenine Nucleotides; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antimetabolites, Antineoplastic; Antineoplastic Agents; Arabinonucleosides; Azacitidine; Bevacizumab; Boronic Acids; Bortezomib; Clofarabine; Cytosine; Decitabine; Dioxolanes; Humans; Indoles; Leukemia, Myeloid; Phthalazines; Pyrazines; Pyridines; Pyrroles; Thionucleotides | 2002 |
Epigenetic DNA-(cytosine-5-carbon) modifications: 5-aza-2'-deoxycytidine and DNA-demethylation.
Topics: 5-Methylcytosine; Animals; Antimetabolites, Antineoplastic; Azacitidine; Cell Cycle; Cytosine; Decitabine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA-Cytosine Methylases; Epigenesis, Genetic; Gene Expression Regulation; Humans | 2009 |
Novel and emerging drugs for acute myeloid leukemia: pharmacology and therapeutic activity.
Topics: Adenine Nucleotides; Animals; Arabinonucleosides; Azacitidine; Benzamides; Clofarabine; Cytarabine; Cytosine; Daunorubicin; Decitabine; Dioxolanes; Farnesyltranstransferase; Histone Deacetylase Inhibitors; Humans; Hydrazines; Imatinib Mesylate; Leukemia, Myeloid, Acute; Liposomes; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Sulfonamides; TOR Serine-Threonine Kinases; Valproic Acid; Vascular Endothelial Growth Factor Receptor-1 | 2011 |
Failure of hypomethylating agent-based therapy in myelodysplastic syndromes.
Topics: Adenine Nucleotides; Alemtuzumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Neoplasm; Antineoplastic Agents; Arabinonucleosides; Azacitidine; Clofarabine; Cytosine; Decitabine; Drug Resistance; Drug Substitution; Enzyme Inhibitors; Glutathione; Glycine; Humans; Myelodysplastic Syndromes; Stem Cell Transplantation; Sulfones; Treatment Failure | 2011 |
5-azacytosine compounds in medicinal chemistry: current stage and future perspectives.
Topics: Animals; Anti-HIV Agents; Antineoplastic Agents; Azacitidine; Cytosine; DNA Methylation; Drug Discovery; HIV; HIV Infections; Humans; Neoplasms | 2012 |
Connections between TET proteins and aberrant DNA modification in cancer.
Topics: 5-Methylcytosine; Azacitidine; Cytosine; Decitabine; Dioxygenases; DNA Methylation; DNA Modification Methylases; DNA-Binding Proteins; Hematologic Neoplasms; Humans; Isocitrate Dehydrogenase; Mixed Function Oxygenases; Molecular Targeted Therapy; Mutation; Neoplasms; Proto-Oncogene Proteins; Small Molecule Libraries | 2014 |
[TET2 dysregulation in hematologic malignancies].
Topics: Azacitidine; Cytosine; Decitabine; Dioxygenases; DNA-Binding Proteins; Enzyme Inhibitors; Epigenesis, Genetic; Genetic Predisposition to Disease; Hematologic Neoplasms; Humans; Methylation; Molecular Targeted Therapy; Multigene Family; Mutation; Neoplasm Proteins; Proto-Oncogene Proteins | 2014 |
The p53 protein plays a central role in the mechanism of action of epigentic drugs that alter the methylation of cytosine residues in DNA.
Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Cell Death; Cytosine; Decitabine; DNA Methylation; DNA, Neoplasm; Drug Resistance, Neoplasm; Epigenesis, Genetic; Humans; Mutation; Neoplasms; Tumor Suppressor Protein p53 | 2017 |
1 trial(s) available for azacitidine and cytosine
| Article | Year |
|---|---|
Azacytidine causes complex DNA methylation responses in myeloid leukemia.
Topics: Antineoplastic Agents; Azacitidine; Cell Line, Tumor; Cytosine; Decitabine; DNA Methylation; Genome, Human; Humans; Leukemia, Myeloid; Myelodysplastic Syndromes; Oligonucleotide Array Sequence Analysis | 2008 |
122 other study(ies) available for azacitidine and cytosine
| Article | Year |
|---|---|
Cytidine deaminase: a new genetic polymorphism demonstrated in human granulocytes.
Topics: Azacitidine; Cytarabine; Cytidine; Cytidine Deaminase; Cytosine; Electrophoresis, Starch Gel; Female; Granulocytes; Humans; Leukocytes; Male; Nucleoside Deaminases; Pedigree; Phenotype; Polymorphism, Genetic | 1975 |
Photobiological behaviour of bacteria and phages supplemented with aza-analogoues of nucleic acid bases.
Topics: Adenine; Aza Compounds; Azacitidine; Bacillus cereus; Coliphages; Cytosine; Escherichia coli; Nucleosides; Radiation Effects; Thymine; Ultraviolet Rays; Uracil | 1975 |
Template-directed interference footprinting of cytosine contacts in a protein-DNA complex: potent interference by 5-aza-2'-deoxycytidine.
Topics: Antineoplastic Agents; Azacitidine; Base Sequence; Cytosine; Decitabine; DNA; DNA-Binding Proteins; Electrophoresis, Polyacrylamide Gel; Molecular Sequence Data; Templates, Genetic; X-Ray Diffraction | 1992 |
Inhibition of cephalic neural tube closure by 5-azacytidine in neurulating rat embryos in vitro.
Topics: 5-Methylcytosine; Animals; Azacitidine; Central Nervous System; Cytosine; DNA; DNA Modification Methylases; Embryo, Mammalian; Immunohistochemistry; In Vitro Techniques; Microscopy, Electron; Proteins; Rats | 1992 |
5-Azacytidine-induced reactivation of the human X chromosome-linked PGK1 gene is associated with a large region of cytosine demethylation in the 5' CpG island.
Topics: 5-Methylcytosine; Azacitidine; Cytosine; Electrophoresis, Agar Gel; Electrophoresis, Polyacrylamide Gel; Gene Expression Regulation; Humans; Methylation; Phosphoglycerate Kinase; Regulatory Sequences, Nucleic Acid; Restriction Mapping; X Chromosome | 1990 |
Chromosome aberration induction in Chinese hamster ovary cells by restriction enzymes with different methylation sensitivity.
Topics: Animals; Azacitidine; Cell Line; Chromosome Aberrations; Cricetinae; Cytosine; Decitabine; Deoxyribonuclease HpaII; Deoxyribonucleases, Type II Site-Specific; DNA; Methylation; Substrate Specificity | 1990 |
Effects of sodium butyrate and 5-azacytidine on DNA methylation in human tumor cell lines: variable response to drug treatment and withdrawal.
Topics: 5-Methylcytosine; Azacitidine; Butyrates; Butyric Acid; Cytosine; Deoxyribonuclease HpaII; Deoxyribonucleases, Type II Site-Specific; DNA; Dose-Response Relationship, Drug; HeLa Cells; Humans; Methylation; Tumor Cells, Cultured | 1990 |
Introduction of hygromycin B resistance into Schizophyllum commune: preferential methylation of donor DNA.
Topics: Azacitidine; Blotting, Southern; Cloning, Molecular; Cytosine; DNA, Fungal; Drug Resistance, Microbial; Gene Expression Regulation, Fungal; Hygromycin B; Methylation; Schizophyllum; Transformation, Genetic | 1990 |
Persistence of azacytidine-induced SCEs and genomic methylation in CHO cells in vitro.
Topics: 5-Methylcytosine; Animals; Azacitidine; Cell Cycle; Chromatography, High Pressure Liquid; Cricetinae; Cytosine; In Vitro Techniques; Methylation; Sister Chromatid Exchange | 1990 |
Oxygen concentration regulates 5-azacytidine-induced myogenesis in C3H/10T1/2 cultures.
Topics: 5-Methylcytosine; Animals; Azacitidine; Cell Differentiation; Cell Line; Cytosine; DNA; Kinetics; Methylation; Mice; Mice, Inbred C3H; Muscles; Oxygen | 1990 |
Radioprotective properties of DNA methylation-disrupting agents.
Topics: 5-Methylcytosine; Animals; Azacitidine; Butyrates; Butyric Acid; Cell Survival; Cytosine; Depression, Chemical; DNA; In Vitro Techniques; Methylation; Radiation-Protective Agents; Stimulation, Chemical | 1991 |
High sensitivity to 5-azacytidine in LEC rats, a strain with a metabolic predisposition to hepatitis and hepatoma: possible involvement of DNA methylation in the expression of cytochrome P-450 and gamma-glutamyl transpeptidase.
Topics: 5-Methylcytosine; Animals; Azacitidine; Cytochrome P-450 Enzyme System; Cytosine; Disease Susceptibility; DNA; DNA (Cytosine-5-)-Methyltransferases; gamma-Glutamyltransferase; Gene Expression Regulation, Enzymologic; Hepatitis, Animal; Liver; Liver Neoplasms, Experimental; Methylation; Rats; Rats, Mutant Strains | 1991 |
The interplay of ubiquitous DNA-binding factors, availability of binding sites in the chromatin, and DNA methylation in the differential regulation of phosphoenolpyruvate carboxykinase gene expression.
Topics: Animals; Azacitidine; Base Sequence; Binding Sites; Cell Line; Chromatin; Cytosine; Deoxyribonuclease I; Dinucleoside Phosphates; DNA; DNA-Binding Proteins; Gene Expression Regulation; Methylation; Molecular Sequence Data; Phosphoenolpyruvate Carboxykinase (GTP); Promoter Regions, Genetic; Rats; RNA, Messenger | 1991 |
Gene silencing in mammalian cells by direct incorporation of electroporated 5-methyl-2'-deoxycytidine 5'-triphosphate.
Topics: 5-Methylcytosine; Animals; Azacitidine; Base Composition; Cell Division; Cell Line; Cell Survival; Cricetinae; Cytosine; Deoxycytosine Nucleotides; Drug Resistance; Gene Expression Regulation; Methylation; Mutagenesis; Thioguanine | 1991 |
DNA methylation at asymmetric sites is associated with numerous transition mutations.
Topics: 5-Methylcytosine; Azacitidine; Base Sequence; Biological Evolution; Cytosine; DNA, Ribosomal; Methylation; Mutation; Neurospora crassa | 1985 |
Depression of experimental gastric ulcers and acute pancreatitis in rats treated by 5-azacytosine, 5-azacytidine and their N-methyl derivatives.
Topics: Animals; Azacitidine; Cytosine; Gastric Acid; Gastric Juice; Gastric Mucosa; Male; Pancreatitis; Rats; Rats, Inbred Strains; Stomach Ulcer | 1986 |
DNA methyltransferase levels in tumorigenic and nontumorigenic cells in culture.
Topics: 5-Methylcytosine; Animals; Azacitidine; Cattle; Cells, Cultured; Cricetinae; Cytosine; Decitabine; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA, Neoplasm; Fibroblasts; Gene Expression Regulation; Humans; Mesocricetus; Methylation; Mice; Neoplasm Proteins; Neoplasms, Experimental; Rats | 1986 |
Heterochromatin in the chromosomes of the gorilla: characterization with distamycin A/DAPI, D287/170, chromomycin A3, quinacrine, and 5-azacytidine.
Topics: 5-Methylcytosine; Animals; Azacitidine; Cells, Cultured; Chromomycin A3; Chromosome Banding; Cytosine; Distamycins; DNA; Female; Fluorescent Dyes; Gorilla gorilla; Heterochromatin; Indoles; Lymphocytes; Male; Nucleolus Organizer Region; Primates; Quinacrine; Species Specificity; Staining and Labeling | 1986 |
DNA methylation levels in human and murine melanoma cell lines of varying metastatic potential.
Topics: 5-Methylcytosine; Animals; Azacitidine; Cell Line; Cytosine; DNA, Neoplasm; Humans; Melanoma; Methylation; Mice; Neoplasm Metastasis | 1986 |
Strong effects of 5-azacytidine on the in vitro lifespan of human diploid fibroblasts.
Topics: 5-Methylcytosine; Azacitidine; Cell Division; Cell Line; Cell Survival; Cytarabine; Cytosine; Decitabine; DNA; Fibroblasts; Humans; Methylation | 1986 |
The in vitro lifespan of MRC-5 cells is shortened by 5-azacytidine-induced demethylation.
Topics: 5-Methylcytosine; Azacitidine; Cell Division; Cell Line; Cell Survival; Cytosine; DNA; Fibroblasts; Humans; Methylation | 1987 |
Induction of oligo-2',5'-adenylate synthetase in human lymphoid cells treated with 5-azacytosine and 5-iododeoxyuridine.
Topics: 2',5'-Oligoadenylate Synthetase; Azacitidine; B-Lymphocytes; Cell Line; Cell Transformation, Viral; Cytosine; Enzyme Induction; Herpesvirus 4, Human; Humans; Idoxuridine; Interferon Type I | 1986 |
Suppression of nuclear ADP-ribosyltransferase activity in Ehrlich ascites tumor cells by 5-azacytidine and its analogs.
Topics: Animals; Azacitidine; Carcinoma, Ehrlich Tumor; Cell Nucleus; Cytosine; DNA; Female; Hydroxyurea; Methylation; Mice; Mice, Inbred Strains; Poly(ADP-ribose) Polymerase Inhibitors | 1987 |
DNA methylation alters chromatin structure and regulates Thy-1 expression in EL-4 T cells.
Topics: 5-Methylcytosine; Animals; Antigens, Surface; Azacitidine; Cell Line; Chromatin; Cytosine; Decitabine; DNA, Neoplasm; Ethyl Methanesulfonate; Gene Expression Regulation; Lymphoma; Methylation; Mice; Mice, Inbred C57BL; RNA, Messenger; T-Lymphocytes; Thy-1 Antigens | 1987 |
Time dependence of X gene reactivation induced by 5-azacytidine: possible progressive restructuring of chromatin.
Topics: 5-Methylcytosine; Animals; Azacitidine; Cell Division; Cell Line; Chromatin; Cricetinae; Cytosine; Dosage Compensation, Genetic; Enzyme Induction; Female; Gene Expression Regulation; Humans; Hybrid Cells; Hypoxanthine Phosphoribosyltransferase; Methylation | 1987 |
Differential nuclear protein binding to 5-azacytosine-containing DNA as a potential mechanism for 5-aza-2'-deoxycytidine resistance.
Topics: 5-Methylcytosine; Animals; Azacitidine; Cell Line; Cell Nucleus; Cytarabine; Cytosine; Decitabine; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA-Binding Proteins; Drug Resistance; Methylation; Mice | 1987 |
The asymmetric methylation of CG palindromic dinucleotides increases sister-chromatid exchanges.
Topics: Aedes; Animals; Azacitidine; Base Sequence; Cell Cycle; Cell Line; Cricetinae; Cricetulus; Cytosine; Dinucleoside Phosphates; Female; Guanine; Methylation; Oligonucleotides; Ovary; Sister Chromatid Exchange | 1988 |
High degree of resistance to 5-aza-2'-deoxycytidine in L1210 cells in vitro associated with almost complete loss of deoxycytidine kinase activity.
Topics: 5-Methylcytosine; Animals; Azacitidine; Cell Line; Cells, Cultured; Cytosine; Decitabine; Deoxycytidine; Deoxycytidine Kinase; DNA (Cytosine-5-)-Methyltransferases; Drug Resistance; Leukemia L1210; Mice; Phosphorylation; Phosphotransferases | 1987 |
Changes in hepatic differentiation following treatment of rat fetuses with 5-azacytidine.
Topics: 5-Methylcytosine; alpha-Fetoproteins; Animals; Azacitidine; Cell Differentiation; Cytosine; DNA; Gene Expression Regulation; Hematopoiesis; Liver; Liver Glycogen; Phosphoenolpyruvate Carboxykinase (GTP); Rats; Rats, Inbred Strains; RNA, Messenger; Tyrosine Transaminase | 1988 |
Lack of correlation between DNA-methylating activity and appearance of the immunogenic phenotype in clones of a murine lymphoma treated with mutagens.
Topics: 5-Methylcytosine; Animals; Antigens, Neoplasm; Azacitidine; Clone Cells; Cytosine; DNA, Neoplasm; Female; Leukemia L1210; Male; Methylation; Methylnitronitrosoguanidine; Mice; Mutagens; Phenotype; Triazenes | 1989 |
Gene structure and transcription in mouse cells with extensively demethylated DNA.
Topics: 5-Methylcytosine; Animals; Azacitidine; Chromatin; Clone Cells; Cytosine; Decitabine; DNA; Gene Expression Regulation; Methylation; Mice; Transcription, Genetic | 1989 |
5-azacytidine-induced tumorous transformation and DNA hypomethylation in Nicotiana tissue cultures.
Topics: 5-Methylcytosine; Azacitidine; Cell Transformation, Neoplastic; Cells, Cultured; Cytosine; Deoxyribonuclease HpaII; Deoxyribonucleases, Type II Site-Specific; DNA; Electrophoresis, Agar Gel; Methylation; Plant Tumors; Thymidine; Time Factors | 1989 |
Maintenance of DNA methylation level in SV40-infected human fibroblasts during their in vitro limited proliferative life span.
Topics: 5-Methylcytosine; Azacitidine; Base Composition; Cell Division; Cell Transformation, Viral; Cytosine; Decitabine; DNA; Humans; In Vitro Techniques; Methylation; Simian virus 40 | 1989 |
Induction of hepatitis B virus core gene in human cells by cytosine demethylation in the promoter.
Topics: 5-Methylcytosine; Azacitidine; Cytosine; DNA Restriction Enzymes; DNA, Viral; Gene Expression Regulation; Genes, Viral; Hepatitis B Core Antigens; Humans; Methylation; Promoter Regions, Genetic; Time Factors; Transcription, Genetic; Virus Replication | 1985 |
[Photochemistry of anomalous nucleic acid building blocks. 8. Photochemistry of 6-azacytosine and 6-azacytidine].
Topics: Aza Compounds; Azacitidine; Chromatography; Cytidine; Cytosine; Photochemistry; Polarography; Spectrophotometry; Triazines | 1972 |
SCE and DNA methylation.
Topics: 5-Methylcytosine; Animals; Azacitidine; Benzamides; Cell Line; Cricetinae; Cricetulus; Cytosine; Deer; DNA; DNA Replication; Female; Fibroblasts; Male; Methylation; Mitomycin; Mitomycins; Models, Genetic; Sister Chromatid Exchange | 1984 |
Analogues of 5-methyl cytosine and early embryonic development.
Topics: 5-Methylcytosine; Animals; Azacitidine; Cytosine; DNA; Embryo, Nonmammalian; Gene Expression Regulation; Methylation; Sea Urchins | 1982 |
DNA methylation affecting the expression of murine leukemia proviruses.
Topics: 5-Methylcytosine; AKR murine leukemia virus; Animals; Azacitidine; Cell Line; Cloning, Molecular; Cytosine; DNA Restriction Enzymes; DNA, Viral; Gene Expression Regulation; Genes, Viral; Leukemia Virus, Murine; Methylation; Mice; Moloney murine leukemia virus; Rats; Recombination, Genetic; Transfection | 1982 |
Effect of several inhibitors of enzymatic DNA methylation on the in vivo methylation of different classes of DNA sequences in a cultured human cell line.
Topics: 5-Methylcytosine; Adenosine; Azacitidine; Brain Neoplasms; Cell Division; Cell Line; Cycloleucine; Cytosine; Deoxyadenosines; DNA; DNA Replication; Ethionine; Homocysteine; Humans; Methylation; Thionucleosides; Tubercidin | 1983 |
Specific effects of 5-fluoropyrimidines and 5-azapyrimidines on modification of the 5 position of pyrimidines, in particular the synthesis of 5-methyluracil and 5-methylcytosine in nucleic acids.
Topics: 5-Methylcytosine; Animals; Azacitidine; Cytidine; Cytosine; DNA; Liver; Methylation; Mice; Pyrimidines; RNA, Transfer; Thymine | 1983 |
Kinetics of deamination of 5-aza-2'-deoxycytidine and cytosine arabinoside by human liver cytidine deaminase and its inhibition by 3-deazauridine, thymidine or uracil arabinoside.
Topics: 3-Deazauridine; Adult; Arabinofuranosyluracil; Azacitidine; Cytarabine; Cytidine Deaminase; Cytosine; Decitabine; Humans; Kinetics; Liver; Nucleoside Deaminases; Substrate Specificity; Thymidine | 1983 |
Inhibition of DNA methylation in L1210 leukemic cells by 5-aza-2'-deoxycytidine as a possible mechanism of chemotherapeutic action.
Topics: 5-Methylcytosine; Animals; Antineoplastic Agents; Azacitidine; Cytosine; Decitabine; DNA; DNA (Cytosine-5-)-Methyltransferases; Dose-Response Relationship, Drug; Leukemia L1210; Male; Methylation; Mice | 1983 |
Pulse radiolysis studies of some aza analogues of nucleic acid components.
Topics: Aza Compounds; Azacitidine; Azauridine; Cytosine; Pulse Radiolysis; Thymine; Uracil | 1983 |
The role of cytosine methylation in the control of nopaline synthase gene expression in a plant tumor.
Topics: Amino Acid Oxidoreductases; Azacitidine; Cytosine; DNA; DNA, Neoplasm; Gene Expression Regulation; Malate Dehydrogenase; Methylation; Plant Tumors; Rhizobium | 1983 |
Selection of strongly immunogenic "tum-" variants from tumors at high frequency using 5-azacytidine.
Topics: 5-Methylcytosine; Animals; Antigens, Neoplasm; Azacitidine; Cell Transformation, Neoplastic; Cytosine; DNA; Ethyl Methanesulfonate; Mammary Neoplasms, Experimental; Mast-Cell Sarcoma; Methylnitronitrosoguanidine; Mice; Mice, Inbred A; Mice, Inbred DBA; Mice, Nude; Mutagens; Neoplasm Transplantation; Phenotype | 1984 |
Analysis of the variations in proviral cytosine methylation that accompany transformation and morphological reversion in a line of Rous sarcoma virus-infected Rat-1 cells.
Topics: 5-Methylcytosine; Animals; Avian Sarcoma Viruses; Azacitidine; Base Sequence; Cell Line; Cell Transformation, Neoplastic; Cytosine; DNA Restriction Enzymes; DNA, Viral; Methylation; Rats; Transcription, Genetic | 1984 |
DNA methylation in 5-aza-2'-deoxycytidine-resistant variants of C3H 10T1/2 C18 cells.
Topics: Animals; Azacitidine; Cell Line; Cytosine; Decitabine; DNA; Drug Resistance; Kinetics; Methylation; Mice; Mice, Inbred C3H | 1984 |
Methylation of either cytosine in the recognition sequence CGCG inhibits ThaI cleavage of DNA.
Topics: 5-Methylcytosine; Adenoma; Animals; Azacitidine; Base Sequence; Cell Line; Cytosine; Deoxyribonucleases, Type II Site-Specific; DNA Restriction Enzymes; DNA, Neoplasm; Methylation; Oligodeoxyribonucleotides; Oligonucleotides; Pituitary Neoplasms; Rats; Substrate Specificity | 1984 |
Abnormal chromosome behavior in Neurospora mutants defective in DNA methylation.
Topics: 5-Methylcytosine; Aneuploidy; Azacitidine; Blotting, Southern; Chromosomes, Fungal; Crosses, Genetic; Cytosine; DNA, Fungal; Genes, Fungal; Genetic Complementation Test; Methionine; Methylation; Mutation; Neurospora crassa; Phenotype; S-Adenosylmethionine | 1993 |
Dependence of transcriptional repression on CpG methylation density.
Topics: 5-Methylcytosine; Azacitidine; Butyrates; Cell Nucleus; Cytosine; DNA-Cytosine Methylases; Gene Expression Regulation; Methylation; Transcription, Genetic; Transfection | 1994 |
Amyloid precursor protein gene expression in neural cell lines: influence of DNA cytosine methylation.
Topics: Amyloid beta-Protein Precursor; Animals; Azacitidine; Cell Line; Cytosine; DNA, Neoplasm; Gene Expression; Gene Expression Regulation, Neoplastic; Methylation; Mice; Neuroblastoma; Restriction Mapping; RNA, Messenger; RNA, Ribosomal, 28S | 1994 |
An extra band within the human 9qh+ region that behaves like the surrounding constitutive heterochromatin.
Topics: 5-Methylcytosine; Adult; Azacitidine; Chromosome Aberrations; Chromosome Banding; Chromosomes, Human; Chromosomes, Human, Pair 9; Cytosine; Heterochromatin; Humans; In Situ Hybridization, Fluorescence; Lymphocytes; Male; Methylation; Microscopy, Electron | 1994 |
Demethylation of the estrogen receptor gene in estrogen receptor-negative breast cancer cells can reactivate estrogen receptor gene expression.
Topics: Antineoplastic Agents; Azacitidine; Base Sequence; Breast Neoplasms; Cytosine; Decitabine; DNA, Neoplasm; Gene Expression; Gene Expression Regulation, Neoplastic; Guanine; Humans; Methylation; Molecular Sequence Data; Receptors, Estrogen; RNA, Messenger; Tumor Cells, Cultured | 1995 |
5' CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers.
Topics: 5-Methylcytosine; Alleles; Azacitidine; Base Sequence; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Carrier Proteins; Chromosomes, Human, Pair 9; CpG Islands; Cyclin-Dependent Kinase Inhibitor p16; Cytosine; Decitabine; DNA, Neoplasm; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Glioma; Head and Neck Neoplasms; Humans; Lung Neoplasms; Methylation; Molecular Sequence Data; Neoplasm Proteins; Neoplasms; Sequence Deletion; Transcription, Genetic; Tumor Cells, Cultured | 1995 |
Post-UV survival and mutagenesis in DNA repair-proficient and -deficient strains of Escherichia coli K-12 grown in 5-azacytidine to inhibit DNA cytosine methylation: evidence for mutagenic excision repair.
Topics: Azacitidine; Cytosine; DNA Repair; DNA, Bacterial; Escherichia coli; Methylation; Mutagenesis; Ultraviolet Rays | 1993 |
Isolation of Escherichia coli mutants lacking methylcytosine-dependent restriction systems for cloning extensively methylated frog virus 3 DNA.
Topics: 5-Methylcytosine; Ampicillin Resistance; Azacitidine; Base Sequence; Clone Cells; Cloning, Molecular; Cytosine; DNA Transposable Elements; DNA-Binding Proteins; DNA-Cytosine Methylases; DNA, Viral; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Iridoviridae; Methylation; Molecular Sequence Data; Mutation; Plasmids; Substrate Specificity; Transformation, Genetic | 1993 |
Cytological evidence for 5-azacytidine-induced demethylation of the heterochromatic regions of human chromosomes.
Topics: 5-Methylcytosine; Antibodies, Monoclonal; Azacitidine; Cells, Cultured; Centromere; Chromosomes, Human; Cytosine; DNA Methylation; Heterochromatin; Humans; Karyotyping; Lymphocytes; Male | 1996 |
Cytosine methylation associated with repeat-induced point mutation causes epigenetic gene silencing in Neurospora crassa.
Topics: Azacitidine; Cytosine; DNA Methylation; Drug Resistance, Microbial; Gene Expression Regulation, Fungal; Genes, Fungal; Hygromycin B; Neurospora crassa; Phosphotransferases (Alcohol Group Acceptor); Point Mutation; Repetitive Sequences, Nucleic Acid; RNA, Messenger; S-Adenosylmethionine; Temperature | 1997 |
State of methylation of the human osteocalcin gene in bone-derived and other types of cells.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Binding Sites; Blotting, Southern; Bone and Bones; Chromatin; Cytosine; Deoxyribonuclease HpaII; DNA Methylation; Gene Expression Regulation; Humans; Lymphocytes; Organ Specificity; Osteocalcin; Proteins; RNA, Messenger; Vitamin D | 1997 |
Epigenetic silencing of RNA polymerase I transcription: a role for DNA methylation and histone modification in nucleolar dominance.
Topics: Azacitidine; Brassica; Butyrates; Butyric Acid; Cell Nucleolus; Cytosine; Decitabine; DNA Methylation; Enzyme Inhibitors; Gene Expression Regulation, Plant; Genes, Dominant; Histones; Hydroxamic Acids; Polyploidy; RNA Polymerase I; RNA, Ribosomal; Transcription, Genetic | 1997 |
Epigenetic transcriptional silencing and 5-azacytidine-mediated reactivation of a complex transgene in rice.
Topics: Azacitidine; Bacillus thuringiensis Toxins; Bacterial Proteins; Bacterial Toxins; Cytosine; DNA Methylation; Drug Resistance; Endotoxins; Gene Expression Regulation, Plant; Gene Rearrangement; Genetic Markers; Hemolysin Proteins; Herbicides; Models, Genetic; Organophosphorus Compounds; Oryza; Plants, Genetically Modified; Transcription, Genetic; Transformation, Genetic; Transgenes | 1997 |
The influence of 5-azacytidine on the condensation of the short arm of rye chromosome 1R in Triticum aestivum L. root tip meristematic nuclei.
Topics: Azacitidine; Cell Nucleus; Chromatin; Chromosomes; Cytosine; DNA Methylation; Guanine; Heterochromatin; Meristem; Secale; Triticum | 1997 |
Independent induction of senescence by p16INK4a and p21CIP1 in spontaneously immortalized human fibroblasts.
Topics: 5-Methylcytosine; Azacitidine; Cell Division; Cell Line, Transformed; Cellular Senescence; CpG Islands; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cytosine; Decitabine; DNA Methylation; DNA, Complementary; Gene Expression Regulation; Genes, p16; Genes, p53; Germ-Line Mutation; Humans; Li-Fraumeni Syndrome | 1998 |
Methylation status of CpG sites and methyl-CpG binding proteins are involved in the promoter regulation of the mouse Xist gene.
Topics: Animals; Azacitidine; Base Sequence; Cell Line; Chloramphenicol O-Acetyltransferase; CpG Islands; Cytosine; DNA Methylation; DNA-Binding Proteins; Female; Gene Expression Regulation; Male; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Nuclear Proteins; Promoter Regions, Genetic; RNA, Long Noncoding; RNA, Untranslated; Sequence Analysis, DNA; Thymine; Transcription Factors; X Chromosome | 1998 |
Demethylation by 5-aza-2'-deoxycytidine of specific 5-methylcytosine sites in the promoter region of the retinoic acid receptor beta gene in human colon carcinoma cells.
Topics: 5-Methylcytosine; Adenocarcinoma; Antimetabolites, Antineoplastic; Azacitidine; Base Sequence; Colonic Neoplasms; CpG Islands; Cytosine; Decitabine; DNA Methylation; DNA Primers; DNA, Neoplasm; Humans; Molecular Sequence Data; Polymerase Chain Reaction; Promoter Regions, Genetic; Receptors, Retinoic Acid; Tumor Cells, Cultured | 1998 |
5-Methylcytosine distribution and genome organization in triticale before and after treatment with 5-azacytidine.
Topics: 5-Methylcytosine; Azacitidine; Chromosome Mapping; Cytosine; DNA Methylation; DNA, Plant; DNA, Ribosomal; Edible Grain; Genome, Plant; Plant Roots; Secale; Triticum | 1999 |
Drug-induced hypomethylation of a posttranscriptionally silenced transgene locus of tobacco leads to partial release of silencing.
Topics: 3' Untranslated Regions; Adenine; Azacitidine; Cells, Cultured; Cytosine; DNA Methylation; DNA, Bacterial; Gene Expression Regulation, Plant; Gene Silencing; Genes, Reporter; Kanamycin Kinase; Nicotiana; Open Reading Frames; Plants, Genetically Modified; Plants, Toxic; Transcription, Genetic; Transgenes | 2000 |
Epigenetic regulation of the MGMT and hMSH6 DNA repair genes in cells resistant to methylating agents.
Topics: Alkylating Agents; Antimetabolites, Antineoplastic; Azacitidine; Blotting, Western; CpG Islands; Cytosine; Decitabine; DNA Methylation; DNA Repair; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Gene Silencing; Humans; Luciferases; Methylnitrosourea; O(6)-Methylguanine-DNA Methyltransferase; Plasmids; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Analysis, DNA; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 2000 |
Deoxyribonucleic acid hypomethylation of male germ cells by mitotic and meiotic exposure to 5-azacytidine is associated with altered testicular histology.
Topics: Animals; Apoptosis; Azacitidine; Blotting, Western; Body Weight; Cell Separation; Cytosine; DNA; DNA Methylation; Female; Germ Cells; Male; Meiosis; Mitosis; Pregnancy; Pregnancy Outcome; Proteins; Rats; Rats, Sprague-Dawley; Spermatocytes; Spermatogonia; Testis | 2000 |
Cytosine methylation of an Sp1 site contributes to organ-specific and cell-specific regulation of expression of the lung epithelial gene t1alpha.
Topics: Animals; Azacitidine; Base Sequence; Blotting, Northern; Cell Line; Cytosine; DNA Methylation; DNA Primers; Epithelial Cells; Gene Expression Regulation; Genes, Reporter; Lung; Membrane Glycoproteins; Membrane Proteins; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley; Sp1 Transcription Factor | 2000 |
Cytosine methylation represses glutathione S-transferase P1 (GSTP1) gene expression in human prostate cancer cells.
Topics: Azacitidine; Base Sequence; Cytosine; Decitabine; DNA Methylation; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Gene Silencing; Glutathione S-Transferase pi; Glutathione Transferase; HeLa Cells; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Isoenzymes; Male; Molecular Sequence Data; Plasmids; Promoter Regions, Genetic; Prostatic Neoplasms; Transfection; Tumor Cells, Cultured | 2001 |
On the spontaneous mutability of CpG sites in cultured S49 mouse lymphoma cells.
Topics: 5-Methylcytosine; Animals; Arginine; Azacitidine; Cytosine; Dinucleoside Phosphates; DNA Methylation; DNA, Neoplasm; Hypoxanthine Phosphoribosyltransferase; Lymphoma; Mice; Mutagenesis; Tumor Cells, Cultured | 1999 |
Aberrant methylation and histone deacetylation of cyclooxygenase 2 in gastric cancer.
Topics: Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Cyclooxygenase 2; Cytosine; Decitabine; DNA; DNA Methylation; Enzyme Inhibitors; Gastric Mucosa; Gene Silencing; Histone Deacetylases; Histones; Humans; Hydroxamic Acids; Immunohistochemistry; Isoenzymes; Membrane Proteins; Methylation; Polymorphism, Single-Stranded Conformational; Precipitin Tests; Promoter Regions, Genetic; Prostaglandin-Endoperoxide Synthases; Reverse Transcriptase Polymerase Chain Reaction; Stomach Neoplasms; Sulfites; Transcription, Genetic; Tumor Cells, Cultured | 2002 |
Inhibition of dna methylation by 5-aza-2'-deoxycytidine correlates with induction of K562 cells differentiation.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Butyric Acid; Cell Differentiation; CpG Islands; Cytosine; Decitabine; DNA Methylation; DNA Modification Methylases; Enzyme Inhibitors; Humans; K562 Cells | 2000 |
5S rRNA genes expression is not inhibited by DNA methylation in Arabidopsis.
Topics: Arabidopsis; Azacitidine; Cytosine; DNA Methylation; DNA, Ribosomal; Gene Expression Regulation, Plant; Mutation; Nicotiana; RNA, Ribosomal, 5S; Transcription Factors | 2002 |
Remodeling of DNA methylation and phenotypic and transcriptional changes in synthetic Arabidopsis allotetraploids.
Topics: Arabidopsis; Azacitidine; Chromatin; Crosses, Genetic; Cytosine; Decitabine; DNA Methylation; DNA-Cytosine Methylases; DNA, Complementary; Evolution, Molecular; Gene Expression Regulation; Gene Silencing; Phenotype; Polymorphism, Restriction Fragment Length; Polyploidy; RNA, Messenger | 2002 |
Role of DNA methylation in the suppression of Apaf-1 protein in human leukaemia.
Topics: Apoptosis; Apoptotic Protease-Activating Factor 1; Azacitidine; Cytosine; Decitabine; DNA Methylation; Humans; Leukemia; Polymerase Chain Reaction; Promoter Regions, Genetic; Proteins; Reference Values; Sequence Analysis, DNA; Tumor Cells, Cultured; Ultraviolet Rays | 2003 |
A systematic profile of DNA methylation in human cancer cell lines.
Topics: 5-Methylcytosine; Azacitidine; Cluster Analysis; CpG Islands; Cytosine; Decitabine; DNA Methylation; DNA, Neoplasm; Genes, Tumor Suppressor; Germ-Line Mutation; Humans; Neoplasms; Oligonucleotide Array Sequence Analysis; Tumor Cells, Cultured | 2003 |
Cytosine methylation occurs in a CDC48 homologue and a MADS-box gene during adventitious shoot induction in Petunia leaf explants.
Topics: Amino Acid Sequence; Azacitidine; Cloning, Molecular; Culture Techniques; Cytosine; Decitabine; DNA Methylation; DNA, Plant; Gene Expression Regulation, Plant; MADS Domain Proteins; Microscopy, Electron, Scanning; Molecular Sequence Data; Petunia; Phylogeny; Plant Leaves; Plant Shoots; Sequence Analysis, DNA; Sequence Homology, Amino Acid | 2003 |
Mutant p53 and aberrant cytosine methylation cooperate to silence gene expression.
Topics: Azacitidine; Breast Neoplasms; Chromatin; Cytosine; Desmocollins; DNA Methylation; DNA-Cytosine Methylases; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Tumor Suppressor; Histones; Humans; Membrane Glycoproteins; Mutation; Oligonucleotide Array Sequence Analysis; Promoter Regions, Genetic; Proteins; Serpins; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2003 |
CpG methylation-dependent repression of the human O6-methylguanine-DNA methyltransferase gene linked to chromatin structure alteration.
Topics: Acetylation; Azacitidine; Cells, Cultured; Chromatin; CpG Islands; Cytosine; DNA Methylation; DNA Primers; Enzyme Inhibitors; Gene Expression Regulation; Gene Expression Regulation, Enzymologic; Gene Silencing; HeLa Cells; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Luciferases; O(6)-Methylguanine-DNA Methyltransferase; Precipitin Tests; Promoter Regions, Genetic; Restriction Mapping; Transcription, Genetic | 2003 |
Inhibition of DNA methylation and histone deacetylation prevents murine lung cancer.
Topics: Alleles; Animals; Antimetabolites, Antineoplastic; Azacitidine; Cytosine; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Drug Synergism; Enzyme Inhibitors; Female; Gene Dosage; Histone Deacetylase Inhibitors; Histones; Lung Neoplasms; Male; Mice; Mice, Inbred A; Phenylbutyrates | 2003 |
CpG methylation and transcription factors Sp1 and Sp3 regulate the expression of the human secretin receptor gene.
Topics: Adenocarcinoma; Animals; Azacitidine; Base Composition; Base Sequence; Cattle; Cells, Cultured; CpG Islands; Cytosine; DNA Methylation; DNA Modification Methylases; DNA-Binding Proteins; Drosophila; Enzyme Inhibitors; Gene Expression Regulation; Humans; Molecular Sequence Data; Pancreatic Neoplasms; Promoter Regions, Genetic; Receptors, G-Protein-Coupled; Receptors, Gastrointestinal Hormone; Regulatory Sequences, Nucleic Acid; Sp1 Transcription Factor; Sp3 Transcription Factor; Transcription Factors | 2004 |
Synthesis and anti-cancer activity of some novel 5-azacytosine nucleosides.
Topics: Antineoplastic Agents; Azacitidine; Carbohydrate Conformation; Cell Line, Tumor; Cell Survival; Cytidine; Cytosine; Drug Screening Assays, Antitumor; Humans; Magnetic Resonance Spectroscopy; Molecular Structure; Pentoses; Pyrimidine Nucleosides; Sulfur Compounds | 2003 |
Activation of a rice endogenous retrotransposon Tos17 in tissue culture is accompanied by cytosine demethylation and causes heritable alteration in methylation pattern of flanking genomic regions.
Topics: Azacitidine; Blotting, Northern; Blotting, Southern; Cytosine; DNA Methylation; DNA Primers; DNA Probes; Epigenesis, Genetic; Gene Expression Regulation; Oryza; Retroelements; Reverse Transcriptase Polymerase Chain Reaction | 2004 |
The value of DNA methylation analysis in basic, initial toxicity assessments.
Topics: Animals; Azacitidine; Base Composition; Cell Line, Tumor; Cytosine; DNA Methylation; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Fluorouracil; Gene Expression; Guanine; Mutagenicity Tests; Polymerase Chain Reaction; Rats; Rotenone; Staurosporine | 2004 |
Methylation in the core-promoter region of the chondromodulin-I gene determines the cell-specific expression by regulating the binding of transcriptional activator Sp3.
Topics: 5-Methylcytosine; Azacitidine; Binding Sites; Blotting, Western; Bone and Bones; Cartilage; Cell Line, Tumor; Chondrocytes; Chromatin; CpG Islands; Cytosine; Decitabine; DNA Methylation; DNA-Binding Proteins; Genes, Reporter; Humans; Intercellular Signaling Peptides and Proteins; Luciferases; Membrane Proteins; Precipitin Tests; Promoter Regions, Genetic; Protein Binding; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; RNA, Messenger; RNA, Small Interfering; Sp1 Transcription Factor; Sp3 Transcription Factor; Sulfites; Thymine; Transcription Factors; Transcription, Genetic | 2004 |
Identification of a genomic fragment that directs hematopoietic-specific expression of Rac2 and analysis of the DNA methylation profile of the gene locus.
Topics: 5-Methylcytosine; Animals; Azacitidine; Base Sequence; Cell Line; Codon, Initiator; Cytosine; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Enzyme Inhibitors; Gene Expression Regulation; Hematopoietic System; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Hydroxamic Acids; K562 Cells; Luciferases; Mice; Mice, Transgenic; Molecular Sequence Data; NIH 3T3 Cells; Promoter Regions, Genetic; rac GTP-Binding Proteins; RAC2 GTP-Binding Protein; Recombinant Fusion Proteins; Regulatory Sequences, Nucleic Acid; Transcription Initiation Site; Transfection | 2004 |
DNA hypomethylation in 5-azacytidine-induced early-flowering lines of flax.
Topics: Azacitidine; Base Composition; Crosses, Genetic; Cytosine; DNA Methylation; Flax; Flowers; Phenotype; Time Factors | 2005 |
Chromatin remodeling in plant cell culture: patterns of DNA methylation and histone H3 and H4 acetylation vary during growth of asynchronous potato cell suspensions.
Topics: 5-Methylcytosine; Acetylation; Azacitidine; Chromatin Assembly and Disassembly; Cytosine; DNA Methylation; Epigenesis, Genetic; Histones; Hydroxamic Acids; Solanum tuberosum; Transcription, Genetic | 2005 |
Promoter methylation is associated with the age-dependent loss of N-cadherin in the rat kidney.
Topics: Aging; Animals; Azacitidine; Base Sequence; Cadherins; Cells, Cultured; Cytosine; Decitabine; DNA; DNA Methylation; Enzyme Inhibitors; Gene Expression Regulation; Guanine; Kidney; Liver; Male; Molecular Sequence Data; Promoter Regions, Genetic; Rats; Rats, Inbred F344 | 2008 |
6-Thioguanine perturbs cytosine methylation at the CpG dinucleotide site by DNA methyltransferases in vitro and acts as a DNA demethylating agent in vivo.
Topics: Azacitidine; Cytosine; Decitabine; Dinucleoside Phosphates; DNA; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA-Cytosine Methylases; Humans; Jurkat Cells; Oligodeoxyribonucleotides; Tandem Mass Spectrometry; Thioguanine | 2009 |
Epigenetic regulation of HIV-1 latency by cytosine methylation.
Topics: Azacitidine; CD4-Positive T-Lymphocytes; CpG Islands; Cytosine; Decitabine; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; HIV-1; Humans; Jurkat Cells; NF-kappa B; Promoter Regions, Genetic; Repressor Proteins; RNA, Small Interfering; Transfection; Virus Latency | 2009 |
Repression of induced apoptosis in the 2-cell bovine embryo involves DNA methylation and histone deacetylation.
Topics: 5-Methylcytosine; Animals; Apoptosis; Azacitidine; Blastocyst; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cattle; Cytosine; Decitabine; DNA Fragmentation; DNA Methylation; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Hydroxamic Acids | 2009 |
Tamoxifen epigenetically modulates CXCL12 expression in MCF-7 breast cancer cells.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Hormonal; Azacitidine; Breast Neoplasms; Cell Line, Tumor; Chemokine CXCL12; Cytosine; Decitabine; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Humans; Sequence Analysis, DNA; Tamoxifen | 2010 |
DNA methyltransferase inhibitors increase baculovirus-mediated gene expression in mammalian cells when applied before infection.
Topics: Animals; Azacitidine; Baculoviridae; Cell Line; CHO Cells; Cricetinae; Cricetulus; Cytosine; Decitabine; DNA (Cytosine-5-)-Methyltransferases; Enzyme Inhibitors; Gene Expression Regulation; Genetic Vectors; Humans | 2010 |
Assessing the DNA methylation status of single cells with the comet assay.
Topics: Azacitidine; Comet Assay; Cytosine; Deoxyribonuclease HpaII; DNA Methylation; DNA-Cytosine Methylases; Hep G2 Cells; Heptanoates; Humans; Tyrosinemias | 2010 |
Measuring topology of low-intensity DNA methylation sites for high-throughput assessment of epigenetic drug-induced effects in cancer cells.
Topics: Antineoplastic Agents; Azacitidine; Cell Line, Tumor; Cell Nucleus; Cytidine; Cytosine; DNA Methylation; DNA, Neoplasm; Epigenesis, Genetic; Fluorescence; High-Throughput Screening Assays; Humans; Indoles; Neoplasms; Nucleic Acid Conformation | 2010 |
Novel agents for the treatment of acute myeloid leukemia in the older patient.
Topics: Adenine Nucleotides; Age Factors; Aged; Antineoplastic Agents; Arabinonucleosides; Azacitidine; Clofarabine; Cytosine; Decitabine; Disease-Free Survival; Hematopoietic Stem Cell Transplantation; Humans; Lenalidomide; Leukemia, Myeloid, Acute; Middle Aged; Prognosis; Quinolones; Thalidomide | 2011 |
Characterizing DNA methyltransferases with an ultrasensitive luciferase-linked continuous assay.
Topics: Azacitidine; Bacteria; Cytosine; Deoxyadenosines; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Enzyme Assays; Humans; Kinetics; Light; Luciferases; S-Adenosylhomocysteine; S-Adenosylmethionine; Thionucleosides | 2011 |
Cytosine methylation in miR-153 gene promoters increases the expression of holocarboxylase synthetase, thereby increasing the abundance of histone H4 biotinylation marks in HEK-293 human kidney cells.
Topics: 3' Untranslated Regions; Azacitidine; Binding Sites; Biotinylation; Carbon-Nitrogen Ligases; Cytosine; Decitabine; DNA Methylation; Epigenomics; Gene Expression Regulation; HEK293 Cells; Histones; Humans; Kidney; MicroRNAs; Promoter Regions, Genetic | 2012 |
Induced Pib Expression and Resistance to Magnaporthe grisea are Compromised by Cytosine Demethylation at Critical Promoter Regions in Rice.
Topics: Azacitidine; Cytosine; Disease Resistance; DNA Methylation; Gene Expression Regulation, Plant; Genes, Plant; Magnaporthe; Oryza; Plant Diseases; Plant Proteins; Promoter Regions, Genetic; Sequence Analysis, DNA | 2011 |
Expression of tyrosine hydroxylase is epigenetically regulated in neural stem cells.
Topics: Azacitidine; Base Sequence; CpG Islands; Cytosine; DNA Methylation; Dopaminergic Neurons; Epigenesis, Genetic; Gene Expression Regulation, Developmental; Humans; Molecular Sequence Data; Neural Stem Cells; Promoter Regions, Genetic; Sequence Analysis, DNA; Tyrosine 3-Monooxygenase | 2011 |
Rapid turnover of DNA methylation in human cells.
Topics: Azacitidine; Cell Cycle; Cytosine; DNA; DNA Methylation; Flow Cytometry; Genome, Human; Hep G2 Cells; Humans; Mass Spectrometry | 2012 |
Changes in micro RNA expression in a wild tuber-bearing Solanum species induced by 5-Azacytidine treatment.
Topics: Azacitidine; Cytosine; DNA Methylation; Flowers; Gene Expression Regulation, Plant; Genes, Plant; MicroRNAs; Phenotype; Plant Leaves; Plant Tubers; Solanum; Species Specificity | 2012 |
The dynamic changes of DNA methylation and histone modifications of salt responsive transcription factor genes in soybean.
Topics: Azacitidine; Cytosine; DNA; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Plant; Glycine max; Histones; Oligonucleotide Array Sequence Analysis; Promoter Regions, Genetic; Salts; Sequence Analysis, DNA; Thymine; Transcription Factors; Transcriptional Activation | 2012 |
Cytosine methylation and hydroxymethylation mark DNA for elimination in Oxytricha trifallax.
Topics: Azacitidine; Cytosine; Decitabine; DNA Methylation; DNA, Protozoan; Enzyme Inhibitors; Gene Rearrangement; High-Throughput Nucleotide Sequencing; Mass Spectrometry; Molecular Sequence Data; Oxytricha; Sequence Analysis, DNA | 2012 |
Differences in the methylation patterns of the VaSTS1 and VaSTS10 genes of Vitis amurensis Rupr.
Topics: Acyltransferases; Azacitidine; Cytosine; DNA Methylation; DNA, Plant; Epigenesis, Genetic; Gene Expression Regulation, Plant; Genes, Plant; Resveratrol; Stilbenes; Vitis | 2013 |
Aldosterone reprograms promoter methylation to regulate αENaC transcription in the collecting duct.
Topics: Aldosterone; Animals; Azacitidine; Cell Line; Cells, Cultured; Cytosine; Decitabine; Dioxygenases; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3B; DNA-Binding Proteins; Endodeoxyribonucleases; Epithelial Sodium Channels; Kidney Tubules, Collecting; Mice; Promoter Regions, Genetic; Proto-Oncogene Proteins; Sp1 Transcription Factor; Transcription, Genetic | 2013 |
Real-time dynamics of methyl-CpG-binding domain protein 3 and its role in DNA demethylation by fluorescence correlation spectroscopy.
Topics: 5-Methylcytosine; Azacitidine; Cell Hypoxia; Cytosine; Decitabine; DNA; DNA Modification Methylases; DNA-Binding Proteins; HeLa Cells; Humans; Single-Cell Analysis; Spectrometry, Fluorescence | 2013 |
Effects of chromatin decondensation on alternative NHEJ.
Topics: Animals; Azacitidine; Cell Cycle; Cell Line; Chromatin; Chromosomal Instability; Cytosine; Decitabine; DNA Breaks, Double-Stranded; DNA End-Joining Repair; DNA Ligases; DNA Methylation; Gene Expression Regulation; Humans; Hypotonic Solutions; Mice; Translocation, Genetic | 2013 |
Cytosine DNA methylation influences drug resistance in Escherichia coli through increased sugE expression.
Topics: 5-Methylcytosine; Azacitidine; Bacterial Proteins; Cytosine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Drug Resistance, Bacterial; Enzyme Inhibitors; Escherichia coli; Escherichia coli Proteins; Ethidium; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Gene Knockout Techniques; Membrane Proteins; Microbial Sensitivity Tests; Molecular Chaperones; Sigma Factor | 2014 |
Transcriptome-wide target profiling of RNA cytosine methyltransferases using the mechanism-based enrichment procedure Aza-IP.
Topics: Azacitidine; Cytosine; Gene Expression Profiling; High-Throughput Nucleotide Sequencing; Humans; Immunoprecipitation; tRNA Methyltransferases | 2014 |
The role of gene body cytosine modifications in MGMT expression and sensitivity to temozolomide.
Topics: Antineoplastic Agents, Alkylating; Azacitidine; Cell Line, Tumor; CpG Islands; Cytosine; Dacarbazine; Decitabine; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Quantitative Trait Loci; Temozolomide; Tumor Suppressor Proteins | 2014 |
Trace analysis of methylated and hydroxymethylated cytosines in DNA by isotope-dilution LC-MS/MS: first evidence of DNA methylation in Caenorhabditis elegans.
Topics: 5-Methylcytosine; Animals; Azacitidine; Cadmium; Caenorhabditis elegans; Chromatography, Liquid; Cytosine; Decitabine; Deoxycytidine; DNA; DNA Methylation; Isotope Labeling; Online Systems; Reproducibility of Results; Solid Phase Extraction; Tandem Mass Spectrometry | 2015 |
The hypomethylating agent Decitabine causes a paradoxical increase in 5-hydroxymethylcytosine in human leukemia cells.
Topics: 5-Methylcytosine; Azacitidine; Catalytic Domain; Chromatography, High Pressure Liquid; CpG Islands; Cytosine; Decitabine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA-Binding Proteins; Enzyme-Linked Immunosorbent Assay; HL-60 Cells; Humans; Immunohistochemistry; Leukemia, Myeloid, Acute; MCF-7 Cells; Microscopy, Fluorescence; Mixed Function Oxygenases; Protein Binding; Proto-Oncogene Proteins; Spectrometry, Fluorescence; Tandem Mass Spectrometry | 2015 |
Hydroxymethylcytosine and demethylation of the γ-globin gene promoter during erythroid differentiation.
Topics: 5-Methylcytosine; Animals; Animals, Newborn; Antineoplastic Agents; Ascorbic Acid; Azacitidine; Bone Marrow Cells; Cell Differentiation; Cells, Cultured; Cytosine; Decitabine; Dioxygenases; DNA Methylation; Erythroid Cells; gamma-Globins; Histone Demethylases; Humans; Hydroxyurea; Liver; Papio anubis; Promoter Regions, Genetic; Tranylcypromine | 2015 |
5-azacytidine induces transcriptome changes in Escherichia coli via DNA methylation-dependent and DNA methylation-independent mechanisms.
Topics: 5-Methylcytosine; Azacitidine; Base Sequence; Cell Culture Techniques; Cytosine; DNA Methylation; DNA, Bacterial; Escherichia coli K12; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Gene Knockout Techniques; Genes, Bacterial; Oligonucleotide Array Sequence Analysis; Polymerase Chain Reaction; RNA, Bacterial; Sequence Analysis; Transcriptome; Up-Regulation | 2016 |
Two-color fluorescent cytosine extension assay for the determination of global DNA methylation.
Topics: Azacitidine; Biological Assay; Cytosine; Decitabine; DNA Methylation; DNA Restriction Enzymes; Fluorescence; Hep G2 Cells; Humans; Liver; Primary Cell Culture | 2017 |
Characterization of Cytosine Methylation and the DNA Methyltransferases of
Topics: Azacitidine; Cytosine; DNA Methylation; Methyltransferases; Toxoplasma | 2017 |
Aberrant DNA methylation of mTOR pathway genes promotes inflammatory activation of immune cells in diabetic kidney disease.
Topics: Adolescent; Adoptive Transfer; Adult; Aged; Animals; Azacitidine; Cytosine; Diabetic Nephropathies; Disease Models, Animal; Disease Progression; DNA (Cytosine-5-)-Methyltransferase 1; DNA Methylation; Epigenesis, Genetic; Female; Gene Knockdown Techniques; Humans; Leukocytes, Mononuclear; Male; Mice; Middle Aged; Primary Cell Culture; Promoter Regions, Genetic; Signal Transduction; TOR Serine-Threonine Kinases; Up-Regulation; Young Adult | 2019 |
Insights into the Inhibitory Mechanisms of the Covalent Drugs for DNMT3A.
Topics: Azacitidine; Catalysis; Cytosine; DNA Methyltransferase 3A; DNA Modification Methylases | 2023 |