azacitidine and cytosine

azacitidine has been researched along with cytosine in 142 studies

Research

Studies (142)

TimeframeStudies, this research(%)All Research%
pre-199043 (30.28)18.7374
1990's32 (22.54)18.2507
2000's33 (23.24)29.6817
2010's33 (23.24)24.3611
2020's1 (0.70)2.80

Authors

AuthorsStudies
Anderson, JE; Giblett, ER; Teng, YS1
Hradecna, Z; Jacob, HE; Kittler, L; Löber, G1
Hayashibara, KC; Verdine, GL1
Matsuda, M; Yasutomi, M1
Gartler, SM; Hansen, RS1
Lutze, LH; Morgan, WF; Phillips, JW; Winegar, RA1
Cosgrove, DE; Cox, GS1
Kuipers, AG; Mooibroek, H; Punt, PJ; Sietsma, JH; Wessels, JG1
Bona, R; Cozzi, R; D'Erme, M; Palitti, F; Perticone, P1
Storch, TG1
Catravas, GN; Kalinich, JF; Snyder, SL1
Kurosawa, T; Ookawara, T; Sugiyama, T; Suzuki, K; Taniguchi, N1
Chalkley, R; Faber, S; Granner, D; Ip, T1
Nyce, J1
Selker, EU; Stevens, JN1
Cihák, A; Cízková, J; Korbová, L; Kucerová, V; Pískala, A1
Jones, PA; Kautiainen, TL1
Haaf, T; Ott, G; Scheres, JM; Schmid, M; Wensing, JA1
Everett, CA; Finch, M; Hart, IR; Ormerod, EJ1
Holliday, R1
Fairweather, DS; Fox, M; Margison, GP1
Fujii, N; Oguma, K1
Frahm, J; Hoshino, J; Kröger, H1
Gunter, KC; Sneller, MC1
Heuertz, S; Homman, N; Hors-Cayla, MC1
Jones, PA; Michalowsky, LA2
Bianchi, MS; Bianchi, NO; Larramendy, M1
Veselý, J1
Isham, KR; Kenney, FT; Lee, KL; Rothrock, R1
Fioretti, MC; Fuschiotti, P; Puccetti, P; Romani, L1
Cecchini, E; Citti, L; Durante, M; Geri, C; Natali, L; Nuti Ronchi, V; Parenti, R1
Farooq, M; Holliday, R; Hunter, JL; Matsumura, T1
Chandler, LA; Jones, PA1
Korba, BE; Wilson, VL; Yoakum, GH1
Kittler, L1
Ikushima, T1
Maharajan, V; Pratibha, M; Scarano, E; Tosi, L1
Bird, S; Cowing, D; Gusella, J; Hoffmann, JW; Steffen, D; Tabin, C; Weinberg, RA1
Adams, RL; Burdon, RH1
Adams, JK; Allan, RG; Cooper, IA; Woodcock, DM1
Harris, JS; Lu, LJ; Randerath, K; Tseng, WC1
Bouchard, J; Chabot, GG; Momparler, RL1
Jones, PA; Momparler, RL; Wilson, VL1
Cooper, DN1
Faraggi, M; Riesz, P; Rosenthal, I1
Jones, PA; Riggs, AD1
Clarke, LE; Hepburn, AG; Pearson, L; White, J1
Jones, PA; Taylor, SM; Wilson, V1
Constantinides, PA; Jones, PA; Taylor, SM1
Christman, JK1
Donaghue, TP; Frost, P; Kerbel, RS; Liteplo, RG1
Chiswell, DJ; Gillespie, DA; Searle, S; Wyke, JA1
Flatau, E; Gonzales, FA; Jones, PA; Michalowsky, LA1
Strobl, JS; Thompson, EB1
Claeys, KM; Foss, HM; Roberts, CJ; Selker, EU1
Hsieh, CL1
Cashman, NR; Ledoux, S; Nalbantoglu, J1
Campos, A; Fernández, JL; Gosálvez, J; Goyanes, V; Pereira, S1
Baylin, SB; Davidson, NE; Ferguson, AT; Lapidus, RG1
Baylin, SB; Burger, PC; Gabrielson, E; Herman, JG; Lee, DJ; Mao, L; Merlo, A; Sidransky, D1
Pinney, RJ; Radnedge, L1
Chalasani, S; Dy, L; Essani, K1
de Capoa, A; Di Leandro, M; Giancotti, P; Grappelli, C; Marotta, MR; Menendez, F; Niveleau, A; Poggesi, I; Reynaud, C1
Bird, AP1
Irelan, JT; Selker, EU1
Jääskeläinen, T; Mäenpää, PH; Pirskanen, A; Ryhänen, S1
Chen, ZJ; Pikaard, CS1
Buchholz, WG; Hall, TC; Kumpatla, SP; Teng, W1
Bezdek, M; Egertová, M; Gazdova, B; Glyn, MC; Kovarik, A; Leitch, AR1
Christiansen-Weber, T; Haas, M; Haggblom, C; Vogt, M; Yeargin, J1
Allaman-Pillet, N; Bonny, C; Djemaï, A; Schorderet, DF1
Côté, S; Momparler, RL; Sinnett, D1
Castilho, A; Heslop-Harrison, JS; Neves, N; Rufini-Castiglione, M; Viegas, W1
Depicker, A; Holý, A; Kovarík, A; Van Houdt, H1
Jones, PA; Robertson, KD1
Bearzatto, A; Jiricny, J; Karran, P; Macpherson, P; Szadkowski, M1
Benoit, G; Doerksen, T; Trasler, JM1
Cao, YX; Jean, JC; Williams, MC1
Borniquel, S; Callejas, S; Gutiérrez, JC; Martín-González, A1
Bashambu, M; Singal, R; van Wert, J1
Carter, KB; Cauthron, RD; Gan, J; Steinberg, RA; Zhang, YL1
Fujita, M; Hosokawa, M; Imai, K; Itoh, F; Kikuchi, T; Suzuki, H; Toyota, M; Yamamoto, H1
Czyz, M; Fabianowska-Majewska, K; Wyczechowska, D1
Giles, FJ2
Mathieu, O; Picard, G; Sugiura, M; Tourmente, S; Yukawa, Y1
Comai, L; Davison, J; Madlung, A; Masuelli, RW; Reynolds, SH; Watson, B1
Bertoni, F; Cotter, FE; Fu, WN; Jia, L; Kelsey, SM; McElwaine, SM; Newland, AC1
Avila, S; Esteller, M; Fraga, MF; Guo, M; Herman, JG; Paz, MF; Pollan, M1
Kumar, PP; Kush, A; Lakshmanan, P; Prakash, AP1
Domann, FE; Futscher, BW; Junk, DJ; Munoz-Rodriguez, JL; Oshiro, MM; Watts, GS; Wozniak, RJ1
Bhakat, KK; Mitra, S1
Baylin, SB; Belinsky, SA; Herman, JG; Issa, JP; Klinge, DM; March, TH; Stidley, CA1
Chow, BK; Lee, LT; Ng, SS; Pang, RT; Yung, WH1
Cappellacci, L; Montgomery, JA; Secrist, JA; Tiwari, KN1
Dong, YZ; Fedak, G; Han, FP; Hao, S; Liu, B; Liu, ZL; Shan, XH; Tan, M; Wang, XZ1
Cockerell, GL; Goodman, JI; McKim, JM; Watson, RE1
Aoyama, T; Ishibe, T; Nagayama, S; Nakamura, T; Nakayama, T; Nishijo, K; Okamoto, T; Toguchida, J; Yasura, K1
Butler, JS; Ladd, PD; Skalnik, DG1
Brown, JC; Fieldes, MA; Krech, MJ; Schaeffer, SM1
Law, RD; Suttle, JC1
Akintola, AD; Burghardt, RC; Catania, JM; Chen, G; Crislip, ZL; Parrish, AR; Zimmer, WE1
Bokelmann, I; Lyko, F; Mahlknecht, U; Stresemann, C1
Wang, H; Wang, Y1
Bosque, A; Kauder, SE; Lindqvist, A; Planelles, V; Verdin, E1
Bettuzzi, S; Patra, SK1
Carambula, SF; Hansen, PJ; Oliveira, LJ1
Jagodzinski, PP; Lianeri, M; Lutkowska, A; Pietkiewicz, PP1
Huang, X; Wang, X; Yin, J; Zhong, J1
Dyk, Ev; Gouws, C; Huysamen, C; Koekemoer, G; Pretorius, PJ; Wentzel, JF1
Farkas, DL; Gertych, A; Tajbakhsh, J1
Czemerska, M; Grzybowska-Izydorczyk, O; Pluta, A; Robak, T; Szmigielska-Kapłon, A; Wierzbowska, A; Wolska, A1
Baer, MR; Gojo, I1
Gutierrez, JA; Hemeon, I; Ho, MC; Schramm, VL1
Bao, B; Rodriguez-Melendez, R; Zempleni, J1
Kou, H; Li, Y; Lin, X; Liu, B; Wang, D; Wu, Y; Xia, Q; Xing, S; Xu, C1
Jabbour, E; Kadia, TM; Kantarjian, H1
Choi, EY; Lee, MA; Park, MJ; Yang, JW1
Arànyi, T; Bacquet, C; Páldi, A; Szabó, P; Szüts, D; Yamagata, Y1
Asurmendi, S; Marfil, CF; Masuelli, RW1
Krečmerová, M; Otmar, M1
Ji, D; Li, Q; Li, S; Song, Y; Wang, P; Xiang, F1
Bracht, JR; Landweber, LF; Perlman, DH1
Karetin, YA; Kiselev, KV; Tyunin, AP1
Kone, BC; Kong, Q; Yu, Z1
Cho, IH; Chowdhury, B; Cui, Y; Irudayaraj, J1
Iliakis, G; Moscariello, M1
Mandarano, AH; Militello, KT; Simon, RD; Varechtchouk, O1
Cairns, BR; Khoddami, V1
Dolan, ME; Godley, LA; Moen, EL; Stark, AL; Zhang, W1
Huang, Y; Rao, A1
Sakata-Yanagimoto, M1
Chao, MR; Chen, JL; Hsu, YW; Hu, CW; Yen, CC1
Chevassut, T; Cho, IH; Choudhury, SR; Chowdhury, B; Cooper, B; Cui, Y; Irudayaraj, J; Lossie, AC; McGovern, A1
DeSimone, J; Ibanez, V; Lavelle, D; Mahmud, N; Rivers, A; Ruiz, MA; Vaitkus, K1
Cantatore, S; DiNatale, A; Hennick, SM; Lazatin, JC; Mandarano, AH; Militello, KT; Simon, RD1
Levine, AJ1
Cummings-Lorbetskie, C; Desaulniers, D; Parfett, C; Xiao, GH; Zhou, G1
Chen, L; He, C; Jiang, S; Peng, H; Wei, H; Wu, S1
Chen, G; Chen, H; Dong, Z; Liu, H; Liu, Y; Ren, S; Sun, L; Tang, L; Xia, M; Zhang, L; Zhu, J1
Bai, C; Cheng, G; Li, C; Yang, W; Zhuang, J1

Reviews

19 review(s) available for azacitidine and cytosine

ArticleYear
Hypomethylation of DNA in the regulation of gene expression.
    Developmental biology (New York, N.Y. : 1985), 1988, Volume: 5

    Topics: 5-Methylcytosine; Animals; Azacitidine; Cell Differentiation; Cytosine; DNA; Gene Expression Regulation; Humans; Methylation; Methyltransferases; Neoplasms

1988
DNA methylation in eukaryotes.
    CRC critical reviews in biochemistry, 1982, Volume: 13, Issue:4

    Topics: 5-Methylcytosine; Aging; Animals; Azacitidine; Base Sequence; Chromatin; Cytosine; Deoxyribonuclease HpaII; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA Restriction Enzymes; DNA-Cytosine Methylases; Gene Expression Regulation; Globins; Methylation; Nucleic Acid Conformation; Ovalbumin

1982
Eukaryotic DNA methylation.
    Human genetics, 1983, Volume: 64, Issue:4

    Topics: 5-Methylcytosine; Animals; Azacitidine; Base Composition; Cell Differentiation; Chromosome Mapping; Cytosine; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA Repair; DNA Replication; Eukaryotic Cells; Gene Expression Regulation; Genes; Genes, Viral; Humans; Methylation; Models, Genetic; Mutation; Transcription, Genetic; Transformation, Genetic

1983
5-methylcytosine, gene regulation, and cancer.
    Advances in cancer research, 1983, Volume: 40

    Topics: 5-Methylcytosine; Animals; Azacitidine; Base Sequence; Carcinogens; Cell Transformation, Neoplastic; Cytosine; DNA (Cytosine-5-)-Methyltransferases; DNA Replication; Fibroblasts; Gene Expression Regulation; Humans; Models, Biological; Muscles; Neoplasms; Oncogenes

1983
DNA modification, differentiation, and transformation.
    The Journal of experimental zoology, 1983, Volume: 228, Issue:2

    Topics: 5-Methylcytosine; Animals; Azacitidine; Carcinogens; Cell Differentiation; Cell Line; Cell Survival; Cricetinae; Cricetulus; Cytosine; DNA; DNA (Cytosine-5-)-Methyltransferases; Fibroblasts; Humans; Methylation; Mice; Papio; Phenotype; Rats; Transformation, Genetic

1983
5-Azacytidine, DNA methylation, and differentiation.
    Current topics in microbiology and immunology, 1984, Volume: 108

    Topics: 5-Methylcytosine; Azacitidine; Cell Differentiation; Cytidine; Cytosine; DNA; DNA (Cytosine-5-)-Methyltransferases; Dosage Compensation, Genetic; Female; Gene Expression Regulation; Genes, Viral; Methylation; Methyltransferases; Nucleic Acids; Phosphorylation; RNA, Transfer; X Chromosome

1984
DNA methylation in friend erythroleukemia cells: the effects of chemically induced differentiation and of treatment with inhibitors of DNA methylation.
    Current topics in microbiology and immunology, 1984, Volume: 108

    Topics: 5-Methylcytosine; Animals; Azacitidine; Cell Differentiation; Cell Line; Cytosine; Decitabine; DNA (Cytosine-5-)-Methyltransferases; DNA, Neoplasm; Friend murine leukemia virus; Gene Expression Regulation; Globins; Leukemia, Erythroblastic, Acute; Methylation; Mice

1984
The relationship of DNA methylation to cancer.
    Cancer surveys, 1996, Volume: 28

    Topics: 5-Methylcytosine; Azacitidine; CpG Islands; Cytosine; Decitabine; DNA Methylation; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Methyltransferases; Neoplasms

1996
DNA methylation: past, present and future directions.
    Carcinogenesis, 2000, Volume: 21, Issue:3

    Topics: 5-Methylcytosine; Antimetabolites, Antineoplastic; Azacitidine; Carcinogens; Chromatin; Cytosine; DNA Methylation; DNA Repair; Forecasting; Gene Expression; Humans; Neoplasms

2000
DNA methylation in ciliates: implications in differentiation processes.
    International microbiology : the official journal of the Spanish Society for Microbiology, 2000, Volume: 3, Issue:3

    Topics: 5-Methylcytosine; Adenine; Animals; Azacitidine; Cell Differentiation; Cell Nucleus; Ciliophora; Cytosine; DNA Methylation; DNA Modification Methylases; DNA, Protozoan; Gene Expression Regulation; Gene Expression Regulation, Developmental; Paramecium; Protozoan Proteins; Tetrahymena

2000
Novel agents for the therapy of acute leukemia.
    Current opinion in oncology, 2002, Volume: 14, Issue:1

    Topics: Angiogenesis Inhibitors; Antineoplastic Agents; Azacitidine; Cysteine Endopeptidases; Cytosine; Decitabine; Dioxolanes; DNA Methylation; Humans; Leukemia; Multienzyme Complexes; Neovascularization, Pathologic; Proteasome Endopeptidase Complex

2002
New drugs in acute myeloid leukemia.
    Current oncology reports, 2002, Volume: 4, Issue:5

    Topics: Acute Disease; Adenine Nucleotides; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antimetabolites, Antineoplastic; Antineoplastic Agents; Arabinonucleosides; Azacitidine; Bevacizumab; Boronic Acids; Bortezomib; Clofarabine; Cytosine; Decitabine; Dioxolanes; Humans; Indoles; Leukemia, Myeloid; Phthalazines; Pyrazines; Pyridines; Pyrroles; Thionucleotides

2002
Epigenetic DNA-(cytosine-5-carbon) modifications: 5-aza-2'-deoxycytidine and DNA-demethylation.
    Biochemistry. Biokhimiia, 2009, Volume: 74, Issue:6

    Topics: 5-Methylcytosine; Animals; Antimetabolites, Antineoplastic; Azacitidine; Cell Cycle; Cytosine; Decitabine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA-Cytosine Methylases; Epigenesis, Genetic; Gene Expression Regulation; Humans

2009
Novel and emerging drugs for acute myeloid leukemia: pharmacology and therapeutic activity.
    Current medicinal chemistry, 2011, Volume: 18, Issue:5

    Topics: Adenine Nucleotides; Animals; Arabinonucleosides; Azacitidine; Benzamides; Clofarabine; Cytarabine; Cytosine; Daunorubicin; Decitabine; Dioxolanes; Farnesyltranstransferase; Histone Deacetylase Inhibitors; Humans; Hydrazines; Imatinib Mesylate; Leukemia, Myeloid, Acute; Liposomes; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Sulfonamides; TOR Serine-Threonine Kinases; Valproic Acid; Vascular Endothelial Growth Factor Receptor-1

2011
Failure of hypomethylating agent-based therapy in myelodysplastic syndromes.
    Seminars in oncology, 2011, Volume: 38, Issue:5

    Topics: Adenine Nucleotides; Alemtuzumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Neoplasm; Antineoplastic Agents; Arabinonucleosides; Azacitidine; Clofarabine; Cytosine; Decitabine; Drug Resistance; Drug Substitution; Enzyme Inhibitors; Glutathione; Glycine; Humans; Myelodysplastic Syndromes; Stem Cell Transplantation; Sulfones; Treatment Failure

2011
5-azacytosine compounds in medicinal chemistry: current stage and future perspectives.
    Future medicinal chemistry, 2012, Volume: 4, Issue:8

    Topics: Animals; Anti-HIV Agents; Antineoplastic Agents; Azacitidine; Cytosine; DNA Methylation; Drug Discovery; HIV; HIV Infections; Humans; Neoplasms

2012
Connections between TET proteins and aberrant DNA modification in cancer.
    Trends in genetics : TIG, 2014, Volume: 30, Issue:10

    Topics: 5-Methylcytosine; Azacitidine; Cytosine; Decitabine; Dioxygenases; DNA Methylation; DNA Modification Methylases; DNA-Binding Proteins; Hematologic Neoplasms; Humans; Isocitrate Dehydrogenase; Mixed Function Oxygenases; Molecular Targeted Therapy; Mutation; Neoplasms; Proto-Oncogene Proteins; Small Molecule Libraries

2014
[TET2 dysregulation in hematologic malignancies].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2014, Volume: 55, Issue:10

    Topics: Azacitidine; Cytosine; Decitabine; Dioxygenases; DNA-Binding Proteins; Enzyme Inhibitors; Epigenesis, Genetic; Genetic Predisposition to Disease; Hematologic Neoplasms; Humans; Methylation; Molecular Targeted Therapy; Multigene Family; Mutation; Neoplasm Proteins; Proto-Oncogene Proteins

2014
The p53 protein plays a central role in the mechanism of action of epigentic drugs that alter the methylation of cytosine residues in DNA.
    Oncotarget, 2017, Jan-31, Volume: 8, Issue:5

    Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Cell Death; Cytosine; Decitabine; DNA Methylation; DNA, Neoplasm; Drug Resistance, Neoplasm; Epigenesis, Genetic; Humans; Mutation; Neoplasms; Tumor Suppressor Protein p53

2017

Trials

1 trial(s) available for azacitidine and cytosine

ArticleYear
Azacytidine causes complex DNA methylation responses in myeloid leukemia.
    Molecular cancer therapeutics, 2008, Volume: 7, Issue:9

    Topics: Antineoplastic Agents; Azacitidine; Cell Line, Tumor; Cytosine; Decitabine; DNA Methylation; Genome, Human; Humans; Leukemia, Myeloid; Myelodysplastic Syndromes; Oligonucleotide Array Sequence Analysis

2008

Other Studies

122 other study(ies) available for azacitidine and cytosine

ArticleYear
Cytidine deaminase: a new genetic polymorphism demonstrated in human granulocytes.
    American journal of human genetics, 1975, Volume: 27, Issue:4

    Topics: Azacitidine; Cytarabine; Cytidine; Cytidine Deaminase; Cytosine; Electrophoresis, Starch Gel; Female; Granulocytes; Humans; Leukocytes; Male; Nucleoside Deaminases; Pedigree; Phenotype; Polymorphism, Genetic

1975
Photobiological behaviour of bacteria and phages supplemented with aza-analogoues of nucleic acid bases.
    Zeitschrift fur allgemeine Mikrobiologie, 1975, Volume: 15, Issue:5

    Topics: Adenine; Aza Compounds; Azacitidine; Bacillus cereus; Coliphages; Cytosine; Escherichia coli; Nucleosides; Radiation Effects; Thymine; Ultraviolet Rays; Uracil

1975
Template-directed interference footprinting of cytosine contacts in a protein-DNA complex: potent interference by 5-aza-2'-deoxycytidine.
    Biochemistry, 1992, Nov-24, Volume: 31, Issue:46

    Topics: Antineoplastic Agents; Azacitidine; Base Sequence; Cytosine; Decitabine; DNA; DNA-Binding Proteins; Electrophoresis, Polyacrylamide Gel; Molecular Sequence Data; Templates, Genetic; X-Ray Diffraction

1992
Inhibition of cephalic neural tube closure by 5-azacytidine in neurulating rat embryos in vitro.
    Anatomy and embryology, 1992, Volume: 185, Issue:3

    Topics: 5-Methylcytosine; Animals; Azacitidine; Central Nervous System; Cytosine; DNA; DNA Modification Methylases; Embryo, Mammalian; Immunohistochemistry; In Vitro Techniques; Microscopy, Electron; Proteins; Rats

1992
5-Azacytidine-induced reactivation of the human X chromosome-linked PGK1 gene is associated with a large region of cytosine demethylation in the 5' CpG island.
    Proceedings of the National Academy of Sciences of the United States of America, 1990, Volume: 87, Issue:11

    Topics: 5-Methylcytosine; Azacitidine; Cytosine; Electrophoresis, Agar Gel; Electrophoresis, Polyacrylamide Gel; Gene Expression Regulation; Humans; Methylation; Phosphoglycerate Kinase; Regulatory Sequences, Nucleic Acid; Restriction Mapping; X Chromosome

1990
Chromosome aberration induction in Chinese hamster ovary cells by restriction enzymes with different methylation sensitivity.
    Somatic cell and molecular genetics, 1990, Volume: 16, Issue:3

    Topics: Animals; Azacitidine; Cell Line; Chromosome Aberrations; Cricetinae; Cytosine; Decitabine; Deoxyribonuclease HpaII; Deoxyribonucleases, Type II Site-Specific; DNA; Methylation; Substrate Specificity

1990
Effects of sodium butyrate and 5-azacytidine on DNA methylation in human tumor cell lines: variable response to drug treatment and withdrawal.
    Biochimica et biophysica acta, 1990, Sep-10, Volume: 1087, Issue:1

    Topics: 5-Methylcytosine; Azacitidine; Butyrates; Butyric Acid; Cytosine; Deoxyribonuclease HpaII; Deoxyribonucleases, Type II Site-Specific; DNA; Dose-Response Relationship, Drug; HeLa Cells; Humans; Methylation; Tumor Cells, Cultured

1990
Introduction of hygromycin B resistance into Schizophyllum commune: preferential methylation of donor DNA.
    Molecular & general genetics : MGG, 1990, Volume: 222, Issue:1

    Topics: Azacitidine; Blotting, Southern; Cloning, Molecular; Cytosine; DNA, Fungal; Drug Resistance, Microbial; Gene Expression Regulation, Fungal; Hygromycin B; Methylation; Schizophyllum; Transformation, Genetic

1990
Persistence of azacytidine-induced SCEs and genomic methylation in CHO cells in vitro.
    Mutation research, 1990, Volume: 245, Issue:3

    Topics: 5-Methylcytosine; Animals; Azacitidine; Cell Cycle; Chromatography, High Pressure Liquid; Cricetinae; Cytosine; In Vitro Techniques; Methylation; Sister Chromatid Exchange

1990
Oxygen concentration regulates 5-azacytidine-induced myogenesis in C3H/10T1/2 cultures.
    Biochimica et biophysica acta, 1990, Nov-12, Volume: 1055, Issue:2

    Topics: 5-Methylcytosine; Animals; Azacitidine; Cell Differentiation; Cell Line; Cytosine; DNA; Kinetics; Methylation; Mice; Mice, Inbred C3H; Muscles; Oxygen

1990
Radioprotective properties of DNA methylation-disrupting agents.
    International journal of radiation biology, 1991, Volume: 59, Issue:5

    Topics: 5-Methylcytosine; Animals; Azacitidine; Butyrates; Butyric Acid; Cell Survival; Cytosine; Depression, Chemical; DNA; In Vitro Techniques; Methylation; Radiation-Protective Agents; Stimulation, Chemical

1991
High sensitivity to 5-azacytidine in LEC rats, a strain with a metabolic predisposition to hepatitis and hepatoma: possible involvement of DNA methylation in the expression of cytochrome P-450 and gamma-glutamyl transpeptidase.
    Biochemistry international, 1991, Volume: 23, Issue:1

    Topics: 5-Methylcytosine; Animals; Azacitidine; Cytochrome P-450 Enzyme System; Cytosine; Disease Susceptibility; DNA; DNA (Cytosine-5-)-Methyltransferases; gamma-Glutamyltransferase; Gene Expression Regulation, Enzymologic; Hepatitis, Animal; Liver; Liver Neoplasms, Experimental; Methylation; Rats; Rats, Mutant Strains

1991
The interplay of ubiquitous DNA-binding factors, availability of binding sites in the chromatin, and DNA methylation in the differential regulation of phosphoenolpyruvate carboxykinase gene expression.
    Nucleic acids research, 1991, Sep-11, Volume: 19, Issue:17

    Topics: Animals; Azacitidine; Base Sequence; Binding Sites; Cell Line; Chromatin; Cytosine; Deoxyribonuclease I; Dinucleoside Phosphates; DNA; DNA-Binding Proteins; Gene Expression Regulation; Methylation; Molecular Sequence Data; Phosphoenolpyruvate Carboxykinase (GTP); Promoter Regions, Genetic; Rats; RNA, Messenger

1991
Gene silencing in mammalian cells by direct incorporation of electroporated 5-methyl-2'-deoxycytidine 5'-triphosphate.
    Somatic cell and molecular genetics, 1991, Volume: 17, Issue:6

    Topics: 5-Methylcytosine; Animals; Azacitidine; Base Composition; Cell Division; Cell Line; Cell Survival; Cricetinae; Cytosine; Deoxycytosine Nucleotides; Drug Resistance; Gene Expression Regulation; Methylation; Mutagenesis; Thioguanine

1991
DNA methylation at asymmetric sites is associated with numerous transition mutations.
    Proceedings of the National Academy of Sciences of the United States of America, 1985, Volume: 82, Issue:23

    Topics: 5-Methylcytosine; Azacitidine; Base Sequence; Biological Evolution; Cytosine; DNA, Ribosomal; Methylation; Mutation; Neurospora crassa

1985
Depression of experimental gastric ulcers and acute pancreatitis in rats treated by 5-azacytosine, 5-azacytidine and their N-methyl derivatives.
    Experientia, 1986, Jan-15, Volume: 42, Issue:1

    Topics: Animals; Azacitidine; Cytosine; Gastric Acid; Gastric Juice; Gastric Mucosa; Male; Pancreatitis; Rats; Rats, Inbred Strains; Stomach Ulcer

1986
DNA methyltransferase levels in tumorigenic and nontumorigenic cells in culture.
    The Journal of biological chemistry, 1986, Feb-05, Volume: 261, Issue:4

    Topics: 5-Methylcytosine; Animals; Azacitidine; Cattle; Cells, Cultured; Cricetinae; Cytosine; Decitabine; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA, Neoplasm; Fibroblasts; Gene Expression Regulation; Humans; Mesocricetus; Methylation; Mice; Neoplasm Proteins; Neoplasms, Experimental; Rats

1986
Heterochromatin in the chromosomes of the gorilla: characterization with distamycin A/DAPI, D287/170, chromomycin A3, quinacrine, and 5-azacytidine.
    Cytogenetics and cell genetics, 1986, Volume: 41, Issue:2

    Topics: 5-Methylcytosine; Animals; Azacitidine; Cells, Cultured; Chromomycin A3; Chromosome Banding; Cytosine; Distamycins; DNA; Female; Fluorescent Dyes; Gorilla gorilla; Heterochromatin; Indoles; Lymphocytes; Male; Nucleolus Organizer Region; Primates; Quinacrine; Species Specificity; Staining and Labeling

1986
DNA methylation levels in human and murine melanoma cell lines of varying metastatic potential.
    Cancer research, 1986, Volume: 46, Issue:9

    Topics: 5-Methylcytosine; Animals; Azacitidine; Cell Line; Cytosine; DNA, Neoplasm; Humans; Melanoma; Methylation; Mice; Neoplasm Metastasis

1986
Strong effects of 5-azacytidine on the in vitro lifespan of human diploid fibroblasts.
    Experimental cell research, 1986, Volume: 166, Issue:2

    Topics: 5-Methylcytosine; Azacitidine; Cell Division; Cell Line; Cell Survival; Cytarabine; Cytosine; Decitabine; DNA; Fibroblasts; Humans; Methylation

1986
The in vitro lifespan of MRC-5 cells is shortened by 5-azacytidine-induced demethylation.
    Experimental cell research, 1987, Volume: 168, Issue:1

    Topics: 5-Methylcytosine; Azacitidine; Cell Division; Cell Line; Cell Survival; Cytosine; DNA; Fibroblasts; Humans; Methylation

1987
Induction of oligo-2',5'-adenylate synthetase in human lymphoid cells treated with 5-azacytosine and 5-iododeoxyuridine.
    The Journal of general virology, 1986, Volume: 67 ( Pt 11)

    Topics: 2',5'-Oligoadenylate Synthetase; Azacitidine; B-Lymphocytes; Cell Line; Cell Transformation, Viral; Cytosine; Enzyme Induction; Herpesvirus 4, Human; Humans; Idoxuridine; Interferon Type I

1986
Suppression of nuclear ADP-ribosyltransferase activity in Ehrlich ascites tumor cells by 5-azacytidine and its analogs.
    Biochemical and biophysical research communications, 1987, Jan-30, Volume: 142, Issue:2

    Topics: Animals; Azacitidine; Carcinoma, Ehrlich Tumor; Cell Nucleus; Cytosine; DNA; Female; Hydroxyurea; Methylation; Mice; Mice, Inbred Strains; Poly(ADP-ribose) Polymerase Inhibitors

1987
DNA methylation alters chromatin structure and regulates Thy-1 expression in EL-4 T cells.
    Journal of immunology (Baltimore, Md. : 1950), 1987, May-15, Volume: 138, Issue:10

    Topics: 5-Methylcytosine; Animals; Antigens, Surface; Azacitidine; Cell Line; Chromatin; Cytosine; Decitabine; DNA, Neoplasm; Ethyl Methanesulfonate; Gene Expression Regulation; Lymphoma; Methylation; Mice; Mice, Inbred C57BL; RNA, Messenger; T-Lymphocytes; Thy-1 Antigens

1987
Time dependence of X gene reactivation induced by 5-azacytidine: possible progressive restructuring of chromatin.
    Experimental cell research, 1987, Volume: 172, Issue:2

    Topics: 5-Methylcytosine; Animals; Azacitidine; Cell Division; Cell Line; Chromatin; Cricetinae; Cytosine; Dosage Compensation, Genetic; Enzyme Induction; Female; Gene Expression Regulation; Humans; Hybrid Cells; Hypoxanthine Phosphoribosyltransferase; Methylation

1987
Differential nuclear protein binding to 5-azacytosine-containing DNA as a potential mechanism for 5-aza-2'-deoxycytidine resistance.
    Molecular and cellular biology, 1987, Volume: 7, Issue:9

    Topics: 5-Methylcytosine; Animals; Azacitidine; Cell Line; Cell Nucleus; Cytarabine; Cytosine; Decitabine; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA-Binding Proteins; Drug Resistance; Methylation; Mice

1987
The asymmetric methylation of CG palindromic dinucleotides increases sister-chromatid exchanges.
    Mutation research, 1988, Volume: 197, Issue:1

    Topics: Aedes; Animals; Azacitidine; Base Sequence; Cell Cycle; Cell Line; Cricetinae; Cricetulus; Cytosine; Dinucleoside Phosphates; Female; Guanine; Methylation; Oligonucleotides; Ovary; Sister Chromatid Exchange

1988
High degree of resistance to 5-aza-2'-deoxycytidine in L1210 cells in vitro associated with almost complete loss of deoxycytidine kinase activity.
    Neoplasma, 1987, Volume: 34, Issue:6

    Topics: 5-Methylcytosine; Animals; Azacitidine; Cell Line; Cells, Cultured; Cytosine; Decitabine; Deoxycytidine; Deoxycytidine Kinase; DNA (Cytosine-5-)-Methyltransferases; Drug Resistance; Leukemia L1210; Mice; Phosphorylation; Phosphotransferases

1987
Changes in hepatic differentiation following treatment of rat fetuses with 5-azacytidine.
    Archives of biochemistry and biophysics, 1988, Volume: 263, Issue:2

    Topics: 5-Methylcytosine; alpha-Fetoproteins; Animals; Azacitidine; Cell Differentiation; Cytosine; DNA; Gene Expression Regulation; Hematopoiesis; Liver; Liver Glycogen; Phosphoenolpyruvate Carboxykinase (GTP); Rats; Rats, Inbred Strains; RNA, Messenger; Tyrosine Transaminase

1988
Lack of correlation between DNA-methylating activity and appearance of the immunogenic phenotype in clones of a murine lymphoma treated with mutagens.
    Cancer immunology, immunotherapy : CII, 1989, Volume: 29, Issue:2

    Topics: 5-Methylcytosine; Animals; Antigens, Neoplasm; Azacitidine; Clone Cells; Cytosine; DNA, Neoplasm; Female; Leukemia L1210; Male; Methylation; Methylnitronitrosoguanidine; Mice; Mutagens; Phenotype; Triazenes

1989
Gene structure and transcription in mouse cells with extensively demethylated DNA.
    Molecular and cellular biology, 1989, Volume: 9, Issue:3

    Topics: 5-Methylcytosine; Animals; Azacitidine; Chromatin; Clone Cells; Cytosine; Decitabine; DNA; Gene Expression Regulation; Methylation; Mice; Transcription, Genetic

1989
5-azacytidine-induced tumorous transformation and DNA hypomethylation in Nicotiana tissue cultures.
    Developmental genetics, 1989, Volume: 10, Issue:4

    Topics: 5-Methylcytosine; Azacitidine; Cell Transformation, Neoplastic; Cells, Cultured; Cytosine; Deoxyribonuclease HpaII; Deoxyribonucleases, Type II Site-Specific; DNA; Electrophoresis, Agar Gel; Methylation; Plant Tumors; Thymidine; Time Factors

1989
Maintenance of DNA methylation level in SV40-infected human fibroblasts during their in vitro limited proliferative life span.
    Experimental cell research, 1989, Volume: 184, Issue:1

    Topics: 5-Methylcytosine; Azacitidine; Base Composition; Cell Division; Cell Transformation, Viral; Cytosine; Decitabine; DNA; Humans; In Vitro Techniques; Methylation; Simian virus 40

1989
Induction of hepatitis B virus core gene in human cells by cytosine demethylation in the promoter.
    Science (New York, N.Y.), 1985, May-31, Volume: 228, Issue:4703

    Topics: 5-Methylcytosine; Azacitidine; Cytosine; DNA Restriction Enzymes; DNA, Viral; Gene Expression Regulation; Genes, Viral; Hepatitis B Core Antigens; Humans; Methylation; Promoter Regions, Genetic; Time Factors; Transcription, Genetic; Virus Replication

1985
[Photochemistry of anomalous nucleic acid building blocks. 8. Photochemistry of 6-azacytosine and 6-azacytidine].
    Photochemistry and photobiology, 1972, Volume: 16, Issue:1

    Topics: Aza Compounds; Azacitidine; Chromatography; Cytidine; Cytosine; Photochemistry; Polarography; Spectrophotometry; Triazines

1972
SCE and DNA methylation.
    Basic life sciences, 1984, Volume: 29 Pt A

    Topics: 5-Methylcytosine; Animals; Azacitidine; Benzamides; Cell Line; Cricetinae; Cricetulus; Cytosine; Deer; DNA; DNA Replication; Female; Fibroblasts; Male; Methylation; Mitomycin; Mitomycins; Models, Genetic; Sister Chromatid Exchange

1984
Analogues of 5-methyl cytosine and early embryonic development.
    Progress in clinical and biological research, 1982, Volume: 85 Pt A

    Topics: 5-Methylcytosine; Animals; Azacitidine; Cytosine; DNA; Embryo, Nonmammalian; Gene Expression Regulation; Methylation; Sea Urchins

1982
DNA methylation affecting the expression of murine leukemia proviruses.
    Journal of virology, 1982, Volume: 44, Issue:1

    Topics: 5-Methylcytosine; AKR murine leukemia virus; Animals; Azacitidine; Cell Line; Cloning, Molecular; Cytosine; DNA Restriction Enzymes; DNA, Viral; Gene Expression Regulation; Genes, Viral; Leukemia Virus, Murine; Methylation; Mice; Moloney murine leukemia virus; Rats; Recombination, Genetic; Transfection

1982
Effect of several inhibitors of enzymatic DNA methylation on the in vivo methylation of different classes of DNA sequences in a cultured human cell line.
    Nucleic acids research, 1983, Jan-25, Volume: 11, Issue:2

    Topics: 5-Methylcytosine; Adenosine; Azacitidine; Brain Neoplasms; Cell Division; Cell Line; Cycloleucine; Cytosine; Deoxyadenosines; DNA; DNA Replication; Ethionine; Homocysteine; Humans; Methylation; Thionucleosides; Tubercidin

1983
Specific effects of 5-fluoropyrimidines and 5-azapyrimidines on modification of the 5 position of pyrimidines, in particular the synthesis of 5-methyluracil and 5-methylcytosine in nucleic acids.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1983, Volume: 84

    Topics: 5-Methylcytosine; Animals; Azacitidine; Cytidine; Cytosine; DNA; Liver; Methylation; Mice; Pyrimidines; RNA, Transfer; Thymine

1983
Kinetics of deamination of 5-aza-2'-deoxycytidine and cytosine arabinoside by human liver cytidine deaminase and its inhibition by 3-deazauridine, thymidine or uracil arabinoside.
    Biochemical pharmacology, 1983, Apr-01, Volume: 32, Issue:7

    Topics: 3-Deazauridine; Adult; Arabinofuranosyluracil; Azacitidine; Cytarabine; Cytidine Deaminase; Cytosine; Decitabine; Humans; Kinetics; Liver; Nucleoside Deaminases; Substrate Specificity; Thymidine

1983
Inhibition of DNA methylation in L1210 leukemic cells by 5-aza-2'-deoxycytidine as a possible mechanism of chemotherapeutic action.
    Cancer research, 1983, Volume: 43, Issue:8

    Topics: 5-Methylcytosine; Animals; Antineoplastic Agents; Azacitidine; Cytosine; Decitabine; DNA; DNA (Cytosine-5-)-Methyltransferases; Dose-Response Relationship, Drug; Leukemia L1210; Male; Methylation; Mice

1983
Pulse radiolysis studies of some aza analogues of nucleic acid components.
    International journal of radiation biology and related studies in physics, chemistry, and medicine, 1983, Volume: 44, Issue:5

    Topics: Aza Compounds; Azacitidine; Azauridine; Cytosine; Pulse Radiolysis; Thymine; Uracil

1983
The role of cytosine methylation in the control of nopaline synthase gene expression in a plant tumor.
    Journal of molecular and applied genetics, 1983, Volume: 2, Issue:3

    Topics: Amino Acid Oxidoreductases; Azacitidine; Cytosine; DNA; DNA, Neoplasm; Gene Expression Regulation; Malate Dehydrogenase; Methylation; Plant Tumors; Rhizobium

1983
Selection of strongly immunogenic "tum-" variants from tumors at high frequency using 5-azacytidine.
    The Journal of experimental medicine, 1984, May-01, Volume: 159, Issue:5

    Topics: 5-Methylcytosine; Animals; Antigens, Neoplasm; Azacitidine; Cell Transformation, Neoplastic; Cytosine; DNA; Ethyl Methanesulfonate; Mammary Neoplasms, Experimental; Mast-Cell Sarcoma; Methylnitronitrosoguanidine; Mice; Mice, Inbred A; Mice, Inbred DBA; Mice, Nude; Mutagens; Neoplasm Transplantation; Phenotype

1984
Analysis of the variations in proviral cytosine methylation that accompany transformation and morphological reversion in a line of Rous sarcoma virus-infected Rat-1 cells.
    Nucleic acids research, 1984, Jul-11, Volume: 12, Issue:13

    Topics: 5-Methylcytosine; Animals; Avian Sarcoma Viruses; Azacitidine; Base Sequence; Cell Line; Cell Transformation, Neoplastic; Cytosine; DNA Restriction Enzymes; DNA, Viral; Methylation; Rats; Transcription, Genetic

1984
DNA methylation in 5-aza-2'-deoxycytidine-resistant variants of C3H 10T1/2 C18 cells.
    Molecular and cellular biology, 1984, Volume: 4, Issue:10

    Topics: Animals; Azacitidine; Cell Line; Cytosine; Decitabine; DNA; Drug Resistance; Kinetics; Methylation; Mice; Mice, Inbred C3H

1984
Methylation of either cytosine in the recognition sequence CGCG inhibits ThaI cleavage of DNA.
    Nucleic acids research, 1984, Nov-12, Volume: 12, Issue:21

    Topics: 5-Methylcytosine; Adenoma; Animals; Azacitidine; Base Sequence; Cell Line; Cytosine; Deoxyribonucleases, Type II Site-Specific; DNA Restriction Enzymes; DNA, Neoplasm; Methylation; Oligodeoxyribonucleotides; Oligonucleotides; Pituitary Neoplasms; Rats; Substrate Specificity

1984
Abnormal chromosome behavior in Neurospora mutants defective in DNA methylation.
    Science (New York, N.Y.), 1993, Dec-10, Volume: 262, Issue:5140

    Topics: 5-Methylcytosine; Aneuploidy; Azacitidine; Blotting, Southern; Chromosomes, Fungal; Crosses, Genetic; Cytosine; DNA, Fungal; Genes, Fungal; Genetic Complementation Test; Methionine; Methylation; Mutation; Neurospora crassa; Phenotype; S-Adenosylmethionine

1993
Dependence of transcriptional repression on CpG methylation density.
    Molecular and cellular biology, 1994, Volume: 14, Issue:8

    Topics: 5-Methylcytosine; Azacitidine; Butyrates; Cell Nucleus; Cytosine; DNA-Cytosine Methylases; Gene Expression Regulation; Methylation; Transcription, Genetic; Transfection

1994
Amyloid precursor protein gene expression in neural cell lines: influence of DNA cytosine methylation.
    Brain research. Molecular brain research, 1994, Volume: 24, Issue:1-4

    Topics: Amyloid beta-Protein Precursor; Animals; Azacitidine; Cell Line; Cytosine; DNA, Neoplasm; Gene Expression; Gene Expression Regulation, Neoplastic; Methylation; Mice; Neuroblastoma; Restriction Mapping; RNA, Messenger; RNA, Ribosomal, 28S

1994
An extra band within the human 9qh+ region that behaves like the surrounding constitutive heterochromatin.
    Journal of medical genetics, 1994, Volume: 31, Issue:8

    Topics: 5-Methylcytosine; Adult; Azacitidine; Chromosome Aberrations; Chromosome Banding; Chromosomes, Human; Chromosomes, Human, Pair 9; Cytosine; Heterochromatin; Humans; In Situ Hybridization, Fluorescence; Lymphocytes; Male; Methylation; Microscopy, Electron

1994
Demethylation of the estrogen receptor gene in estrogen receptor-negative breast cancer cells can reactivate estrogen receptor gene expression.
    Cancer research, 1995, Jun-01, Volume: 55, Issue:11

    Topics: Antineoplastic Agents; Azacitidine; Base Sequence; Breast Neoplasms; Cytosine; Decitabine; DNA, Neoplasm; Gene Expression; Gene Expression Regulation, Neoplastic; Guanine; Humans; Methylation; Molecular Sequence Data; Receptors, Estrogen; RNA, Messenger; Tumor Cells, Cultured

1995
5' CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers.
    Nature medicine, 1995, Volume: 1, Issue:7

    Topics: 5-Methylcytosine; Alleles; Azacitidine; Base Sequence; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Carrier Proteins; Chromosomes, Human, Pair 9; CpG Islands; Cyclin-Dependent Kinase Inhibitor p16; Cytosine; Decitabine; DNA, Neoplasm; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Glioma; Head and Neck Neoplasms; Humans; Lung Neoplasms; Methylation; Molecular Sequence Data; Neoplasm Proteins; Neoplasms; Sequence Deletion; Transcription, Genetic; Tumor Cells, Cultured

1995
Post-UV survival and mutagenesis in DNA repair-proficient and -deficient strains of Escherichia coli K-12 grown in 5-azacytidine to inhibit DNA cytosine methylation: evidence for mutagenic excision repair.
    The Journal of pharmacy and pharmacology, 1993, Volume: 45, Issue:3

    Topics: Azacitidine; Cytosine; DNA Repair; DNA, Bacterial; Escherichia coli; Methylation; Mutagenesis; Ultraviolet Rays

1993
Isolation of Escherichia coli mutants lacking methylcytosine-dependent restriction systems for cloning extensively methylated frog virus 3 DNA.
    Gene, 1993, Sep-06, Volume: 131, Issue:1

    Topics: 5-Methylcytosine; Ampicillin Resistance; Azacitidine; Base Sequence; Clone Cells; Cloning, Molecular; Cytosine; DNA Transposable Elements; DNA-Binding Proteins; DNA-Cytosine Methylases; DNA, Viral; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Iridoviridae; Methylation; Molecular Sequence Data; Mutation; Plasmids; Substrate Specificity; Transformation, Genetic

1993
Cytological evidence for 5-azacytidine-induced demethylation of the heterochromatic regions of human chromosomes.
    Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology, 1996, Volume: 4, Issue:4

    Topics: 5-Methylcytosine; Antibodies, Monoclonal; Azacitidine; Cells, Cultured; Centromere; Chromosomes, Human; Cytosine; DNA Methylation; Heterochromatin; Humans; Karyotyping; Lymphocytes; Male

1996
Cytosine methylation associated with repeat-induced point mutation causes epigenetic gene silencing in Neurospora crassa.
    Genetics, 1997, Volume: 146, Issue:2

    Topics: Azacitidine; Cytosine; DNA Methylation; Drug Resistance, Microbial; Gene Expression Regulation, Fungal; Genes, Fungal; Hygromycin B; Neurospora crassa; Phosphotransferases (Alcohol Group Acceptor); Point Mutation; Repetitive Sequences, Nucleic Acid; RNA, Messenger; S-Adenosylmethionine; Temperature

1997
State of methylation of the human osteocalcin gene in bone-derived and other types of cells.
    Journal of cellular biochemistry, 1997, Sep-01, Volume: 66, Issue:3

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Binding Sites; Blotting, Southern; Bone and Bones; Chromatin; Cytosine; Deoxyribonuclease HpaII; DNA Methylation; Gene Expression Regulation; Humans; Lymphocytes; Organ Specificity; Osteocalcin; Proteins; RNA, Messenger; Vitamin D

1997
Epigenetic silencing of RNA polymerase I transcription: a role for DNA methylation and histone modification in nucleolar dominance.
    Genes & development, 1997, Aug-15, Volume: 11, Issue:16

    Topics: Azacitidine; Brassica; Butyrates; Butyric Acid; Cell Nucleolus; Cytosine; Decitabine; DNA Methylation; Enzyme Inhibitors; Gene Expression Regulation, Plant; Genes, Dominant; Histones; Hydroxamic Acids; Polyploidy; RNA Polymerase I; RNA, Ribosomal; Transcription, Genetic

1997
Epigenetic transcriptional silencing and 5-azacytidine-mediated reactivation of a complex transgene in rice.
    Plant physiology, 1997, Volume: 115, Issue:2

    Topics: Azacitidine; Bacillus thuringiensis Toxins; Bacterial Proteins; Bacterial Toxins; Cytosine; DNA Methylation; Drug Resistance; Endotoxins; Gene Expression Regulation, Plant; Gene Rearrangement; Genetic Markers; Hemolysin Proteins; Herbicides; Models, Genetic; Organophosphorus Compounds; Oryza; Plants, Genetically Modified; Transcription, Genetic; Transformation, Genetic; Transgenes

1997
The influence of 5-azacytidine on the condensation of the short arm of rye chromosome 1R in Triticum aestivum L. root tip meristematic nuclei.
    Chromosoma, 1997, Volume: 106, Issue:8

    Topics: Azacitidine; Cell Nucleus; Chromatin; Chromosomes; Cytosine; DNA Methylation; Guanine; Heterochromatin; Meristem; Secale; Triticum

1997
Independent induction of senescence by p16INK4a and p21CIP1 in spontaneously immortalized human fibroblasts.
    Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 1998, Volume: 9, Issue:2

    Topics: 5-Methylcytosine; Azacitidine; Cell Division; Cell Line, Transformed; Cellular Senescence; CpG Islands; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cytosine; Decitabine; DNA Methylation; DNA, Complementary; Gene Expression Regulation; Genes, p16; Genes, p53; Germ-Line Mutation; Humans; Li-Fraumeni Syndrome

1998
Methylation status of CpG sites and methyl-CpG binding proteins are involved in the promoter regulation of the mouse Xist gene.
    Gene expression, 1998, Volume: 7, Issue:2

    Topics: Animals; Azacitidine; Base Sequence; Cell Line; Chloramphenicol O-Acetyltransferase; CpG Islands; Cytosine; DNA Methylation; DNA-Binding Proteins; Female; Gene Expression Regulation; Male; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Nuclear Proteins; Promoter Regions, Genetic; RNA, Long Noncoding; RNA, Untranslated; Sequence Analysis, DNA; Thymine; Transcription Factors; X Chromosome

1998
Demethylation by 5-aza-2'-deoxycytidine of specific 5-methylcytosine sites in the promoter region of the retinoic acid receptor beta gene in human colon carcinoma cells.
    Anti-cancer drugs, 1998, Volume: 9, Issue:9

    Topics: 5-Methylcytosine; Adenocarcinoma; Antimetabolites, Antineoplastic; Azacitidine; Base Sequence; Colonic Neoplasms; CpG Islands; Cytosine; Decitabine; DNA Methylation; DNA Primers; DNA, Neoplasm; Humans; Molecular Sequence Data; Polymerase Chain Reaction; Promoter Regions, Genetic; Receptors, Retinoic Acid; Tumor Cells, Cultured

1998
5-Methylcytosine distribution and genome organization in triticale before and after treatment with 5-azacytidine.
    Journal of cell science, 1999, Volume: 112 ( Pt 23)

    Topics: 5-Methylcytosine; Azacitidine; Chromosome Mapping; Cytosine; DNA Methylation; DNA, Plant; DNA, Ribosomal; Edible Grain; Genome, Plant; Plant Roots; Secale; Triticum

1999
Drug-induced hypomethylation of a posttranscriptionally silenced transgene locus of tobacco leads to partial release of silencing.
    FEBS letters, 2000, Feb-04, Volume: 467, Issue:1

    Topics: 3' Untranslated Regions; Adenine; Azacitidine; Cells, Cultured; Cytosine; DNA Methylation; DNA, Bacterial; Gene Expression Regulation, Plant; Gene Silencing; Genes, Reporter; Kanamycin Kinase; Nicotiana; Open Reading Frames; Plants, Genetically Modified; Plants, Toxic; Transcription, Genetic; Transgenes

2000
Epigenetic regulation of the MGMT and hMSH6 DNA repair genes in cells resistant to methylating agents.
    Cancer research, 2000, Jun-15, Volume: 60, Issue:12

    Topics: Alkylating Agents; Antimetabolites, Antineoplastic; Azacitidine; Blotting, Western; CpG Islands; Cytosine; Decitabine; DNA Methylation; DNA Repair; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Gene Silencing; Humans; Luciferases; Methylnitrosourea; O(6)-Methylguanine-DNA Methyltransferase; Plasmids; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Analysis, DNA; Transcription, Genetic; Transfection; Tumor Cells, Cultured

2000
Deoxyribonucleic acid hypomethylation of male germ cells by mitotic and meiotic exposure to 5-azacytidine is associated with altered testicular histology.
    Endocrinology, 2000, Volume: 141, Issue:9

    Topics: Animals; Apoptosis; Azacitidine; Blotting, Western; Body Weight; Cell Separation; Cytosine; DNA; DNA Methylation; Female; Germ Cells; Male; Meiosis; Mitosis; Pregnancy; Pregnancy Outcome; Proteins; Rats; Rats, Sprague-Dawley; Spermatocytes; Spermatogonia; Testis

2000
Cytosine methylation of an Sp1 site contributes to organ-specific and cell-specific regulation of expression of the lung epithelial gene t1alpha.
    The Biochemical journal, 2000, Sep-15, Volume: 350 Pt 3

    Topics: Animals; Azacitidine; Base Sequence; Blotting, Northern; Cell Line; Cytosine; DNA Methylation; DNA Primers; Epithelial Cells; Gene Expression Regulation; Genes, Reporter; Lung; Membrane Glycoproteins; Membrane Proteins; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley; Sp1 Transcription Factor

2000
Cytosine methylation represses glutathione S-transferase P1 (GSTP1) gene expression in human prostate cancer cells.
    Cancer research, 2001, Jun-15, Volume: 61, Issue:12

    Topics: Azacitidine; Base Sequence; Cytosine; Decitabine; DNA Methylation; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Gene Silencing; Glutathione S-Transferase pi; Glutathione Transferase; HeLa Cells; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Isoenzymes; Male; Molecular Sequence Data; Plasmids; Promoter Regions, Genetic; Prostatic Neoplasms; Transfection; Tumor Cells, Cultured

2001
On the spontaneous mutability of CpG sites in cultured S49 mouse lymphoma cells.
    Somatic cell and molecular genetics, 1999, Volume: 25, Issue:3

    Topics: 5-Methylcytosine; Animals; Arginine; Azacitidine; Cytosine; Dinucleoside Phosphates; DNA Methylation; DNA, Neoplasm; Hypoxanthine Phosphoribosyltransferase; Lymphoma; Mice; Mutagenesis; Tumor Cells, Cultured

1999
Aberrant methylation and histone deacetylation of cyclooxygenase 2 in gastric cancer.
    International journal of cancer, 2002, Jan-20, Volume: 97, Issue:3

    Topics: Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Cyclooxygenase 2; Cytosine; Decitabine; DNA; DNA Methylation; Enzyme Inhibitors; Gastric Mucosa; Gene Silencing; Histone Deacetylases; Histones; Humans; Hydroxamic Acids; Immunohistochemistry; Isoenzymes; Membrane Proteins; Methylation; Polymorphism, Single-Stranded Conformational; Precipitin Tests; Promoter Regions, Genetic; Prostaglandin-Endoperoxide Synthases; Reverse Transcriptase Polymerase Chain Reaction; Stomach Neoplasms; Sulfites; Transcription, Genetic; Tumor Cells, Cultured

2002
Inhibition of dna methylation by 5-aza-2'-deoxycytidine correlates with induction of K562 cells differentiation.
    Advances in experimental medicine and biology, 2000, Volume: 486

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Butyric Acid; Cell Differentiation; CpG Islands; Cytosine; Decitabine; DNA Methylation; DNA Modification Methylases; Enzyme Inhibitors; Humans; K562 Cells

2000
5S rRNA genes expression is not inhibited by DNA methylation in Arabidopsis.
    The Plant journal : for cell and molecular biology, 2002, Volume: 29, Issue:3

    Topics: Arabidopsis; Azacitidine; Cytosine; DNA Methylation; DNA, Ribosomal; Gene Expression Regulation, Plant; Mutation; Nicotiana; RNA, Ribosomal, 5S; Transcription Factors

2002
Remodeling of DNA methylation and phenotypic and transcriptional changes in synthetic Arabidopsis allotetraploids.
    Plant physiology, 2002, Volume: 129, Issue:2

    Topics: Arabidopsis; Azacitidine; Chromatin; Crosses, Genetic; Cytosine; Decitabine; DNA Methylation; DNA-Cytosine Methylases; DNA, Complementary; Evolution, Molecular; Gene Expression Regulation; Gene Silencing; Phenotype; Polymorphism, Restriction Fragment Length; Polyploidy; RNA, Messenger

2002
Role of DNA methylation in the suppression of Apaf-1 protein in human leukaemia.
    Oncogene, 2003, Jan-23, Volume: 22, Issue:3

    Topics: Apoptosis; Apoptotic Protease-Activating Factor 1; Azacitidine; Cytosine; Decitabine; DNA Methylation; Humans; Leukemia; Polymerase Chain Reaction; Promoter Regions, Genetic; Proteins; Reference Values; Sequence Analysis, DNA; Tumor Cells, Cultured; Ultraviolet Rays

2003
A systematic profile of DNA methylation in human cancer cell lines.
    Cancer research, 2003, Mar-01, Volume: 63, Issue:5

    Topics: 5-Methylcytosine; Azacitidine; Cluster Analysis; CpG Islands; Cytosine; Decitabine; DNA Methylation; DNA, Neoplasm; Genes, Tumor Suppressor; Germ-Line Mutation; Humans; Neoplasms; Oligonucleotide Array Sequence Analysis; Tumor Cells, Cultured

2003
Cytosine methylation occurs in a CDC48 homologue and a MADS-box gene during adventitious shoot induction in Petunia leaf explants.
    Journal of experimental botany, 2003, Volume: 54, Issue:386

    Topics: Amino Acid Sequence; Azacitidine; Cloning, Molecular; Culture Techniques; Cytosine; Decitabine; DNA Methylation; DNA, Plant; Gene Expression Regulation, Plant; MADS Domain Proteins; Microscopy, Electron, Scanning; Molecular Sequence Data; Petunia; Phylogeny; Plant Leaves; Plant Shoots; Sequence Analysis, DNA; Sequence Homology, Amino Acid

2003
Mutant p53 and aberrant cytosine methylation cooperate to silence gene expression.
    Oncogene, 2003, Jun-05, Volume: 22, Issue:23

    Topics: Azacitidine; Breast Neoplasms; Chromatin; Cytosine; Desmocollins; DNA Methylation; DNA-Cytosine Methylases; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Tumor Suppressor; Histones; Humans; Membrane Glycoproteins; Mutation; Oligonucleotide Array Sequence Analysis; Promoter Regions, Genetic; Proteins; Serpins; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2003
CpG methylation-dependent repression of the human O6-methylguanine-DNA methyltransferase gene linked to chromatin structure alteration.
    Carcinogenesis, 2003, Volume: 24, Issue:8

    Topics: Acetylation; Azacitidine; Cells, Cultured; Chromatin; CpG Islands; Cytosine; DNA Methylation; DNA Primers; Enzyme Inhibitors; Gene Expression Regulation; Gene Expression Regulation, Enzymologic; Gene Silencing; HeLa Cells; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Luciferases; O(6)-Methylguanine-DNA Methyltransferase; Precipitin Tests; Promoter Regions, Genetic; Restriction Mapping; Transcription, Genetic

2003
Inhibition of DNA methylation and histone deacetylation prevents murine lung cancer.
    Cancer research, 2003, Nov-01, Volume: 63, Issue:21

    Topics: Alleles; Animals; Antimetabolites, Antineoplastic; Azacitidine; Cytosine; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Drug Synergism; Enzyme Inhibitors; Female; Gene Dosage; Histone Deacetylase Inhibitors; Histones; Lung Neoplasms; Male; Mice; Mice, Inbred A; Phenylbutyrates

2003
CpG methylation and transcription factors Sp1 and Sp3 regulate the expression of the human secretin receptor gene.
    Molecular endocrinology (Baltimore, Md.), 2004, Volume: 18, Issue:2

    Topics: Adenocarcinoma; Animals; Azacitidine; Base Composition; Base Sequence; Cattle; Cells, Cultured; CpG Islands; Cytosine; DNA Methylation; DNA Modification Methylases; DNA-Binding Proteins; Drosophila; Enzyme Inhibitors; Gene Expression Regulation; Humans; Molecular Sequence Data; Pancreatic Neoplasms; Promoter Regions, Genetic; Receptors, G-Protein-Coupled; Receptors, Gastrointestinal Hormone; Regulatory Sequences, Nucleic Acid; Sp1 Transcription Factor; Sp3 Transcription Factor; Transcription Factors

2004
Synthesis and anti-cancer activity of some novel 5-azacytosine nucleosides.
    Nucleosides, nucleotides & nucleic acids, 2003, Volume: 22, Issue:12

    Topics: Antineoplastic Agents; Azacitidine; Carbohydrate Conformation; Cell Line, Tumor; Cell Survival; Cytidine; Cytosine; Drug Screening Assays, Antitumor; Humans; Magnetic Resonance Spectroscopy; Molecular Structure; Pentoses; Pyrimidine Nucleosides; Sulfur Compounds

2003
Activation of a rice endogenous retrotransposon Tos17 in tissue culture is accompanied by cytosine demethylation and causes heritable alteration in methylation pattern of flanking genomic regions.
    TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik, 2004, Volume: 109, Issue:1

    Topics: Azacitidine; Blotting, Northern; Blotting, Southern; Cytosine; DNA Methylation; DNA Primers; DNA Probes; Epigenesis, Genetic; Gene Expression Regulation; Oryza; Retroelements; Reverse Transcriptase Polymerase Chain Reaction

2004
The value of DNA methylation analysis in basic, initial toxicity assessments.
    Toxicological sciences : an official journal of the Society of Toxicology, 2004, Volume: 79, Issue:1

    Topics: Animals; Azacitidine; Base Composition; Cell Line, Tumor; Cytosine; DNA Methylation; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Fluorouracil; Gene Expression; Guanine; Mutagenicity Tests; Polymerase Chain Reaction; Rats; Rotenone; Staurosporine

2004
Methylation in the core-promoter region of the chondromodulin-I gene determines the cell-specific expression by regulating the binding of transcriptional activator Sp3.
    The Journal of biological chemistry, 2004, Jul-02, Volume: 279, Issue:27

    Topics: 5-Methylcytosine; Azacitidine; Binding Sites; Blotting, Western; Bone and Bones; Cartilage; Cell Line, Tumor; Chondrocytes; Chromatin; CpG Islands; Cytosine; Decitabine; DNA Methylation; DNA-Binding Proteins; Genes, Reporter; Humans; Intercellular Signaling Peptides and Proteins; Luciferases; Membrane Proteins; Precipitin Tests; Promoter Regions, Genetic; Protein Binding; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; RNA, Messenger; RNA, Small Interfering; Sp1 Transcription Factor; Sp3 Transcription Factor; Sulfites; Thymine; Transcription Factors; Transcription, Genetic

2004
Identification of a genomic fragment that directs hematopoietic-specific expression of Rac2 and analysis of the DNA methylation profile of the gene locus.
    Gene, 2004, Oct-27, Volume: 341

    Topics: 5-Methylcytosine; Animals; Azacitidine; Base Sequence; Cell Line; Codon, Initiator; Cytosine; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Enzyme Inhibitors; Gene Expression Regulation; Hematopoietic System; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Hydroxamic Acids; K562 Cells; Luciferases; Mice; Mice, Transgenic; Molecular Sequence Data; NIH 3T3 Cells; Promoter Regions, Genetic; rac GTP-Binding Proteins; RAC2 GTP-Binding Protein; Recombinant Fusion Proteins; Regulatory Sequences, Nucleic Acid; Transcription Initiation Site; Transfection

2004
DNA hypomethylation in 5-azacytidine-induced early-flowering lines of flax.
    TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik, 2005, Volume: 111, Issue:1

    Topics: Azacitidine; Base Composition; Crosses, Genetic; Cytosine; DNA Methylation; Flax; Flowers; Phenotype; Time Factors

2005
Chromatin remodeling in plant cell culture: patterns of DNA methylation and histone H3 and H4 acetylation vary during growth of asynchronous potato cell suspensions.
    Plant physiology and biochemistry : PPB, 2005, Volume: 43, Issue:6

    Topics: 5-Methylcytosine; Acetylation; Azacitidine; Chromatin Assembly and Disassembly; Cytosine; DNA Methylation; Epigenesis, Genetic; Histones; Hydroxamic Acids; Solanum tuberosum; Transcription, Genetic

2005
Promoter methylation is associated with the age-dependent loss of N-cadherin in the rat kidney.
    American journal of physiology. Renal physiology, 2008, Volume: 294, Issue:1

    Topics: Aging; Animals; Azacitidine; Base Sequence; Cadherins; Cells, Cultured; Cytosine; Decitabine; DNA; DNA Methylation; Enzyme Inhibitors; Gene Expression Regulation; Guanine; Kidney; Liver; Male; Molecular Sequence Data; Promoter Regions, Genetic; Rats; Rats, Inbred F344

2008
6-Thioguanine perturbs cytosine methylation at the CpG dinucleotide site by DNA methyltransferases in vitro and acts as a DNA demethylating agent in vivo.
    Biochemistry, 2009, Mar-17, Volume: 48, Issue:10

    Topics: Azacitidine; Cytosine; Decitabine; Dinucleoside Phosphates; DNA; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA-Cytosine Methylases; Humans; Jurkat Cells; Oligodeoxyribonucleotides; Tandem Mass Spectrometry; Thioguanine

2009
Epigenetic regulation of HIV-1 latency by cytosine methylation.
    PLoS pathogens, 2009, Volume: 5, Issue:6

    Topics: Azacitidine; CD4-Positive T-Lymphocytes; CpG Islands; Cytosine; Decitabine; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; HIV-1; Humans; Jurkat Cells; NF-kappa B; Promoter Regions, Genetic; Repressor Proteins; RNA, Small Interfering; Transfection; Virus Latency

2009
Repression of induced apoptosis in the 2-cell bovine embryo involves DNA methylation and histone deacetylation.
    Biochemical and biophysical research communications, 2009, Oct-16, Volume: 388, Issue:2

    Topics: 5-Methylcytosine; Animals; Apoptosis; Azacitidine; Blastocyst; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cattle; Cytosine; Decitabine; DNA Fragmentation; DNA Methylation; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Hydroxamic Acids

2009
Tamoxifen epigenetically modulates CXCL12 expression in MCF-7 breast cancer cells.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2010, Volume: 64, Issue:1

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Hormonal; Azacitidine; Breast Neoplasms; Cell Line, Tumor; Chemokine CXCL12; Cytosine; Decitabine; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Humans; Sequence Analysis, DNA; Tamoxifen

2010
DNA methyltransferase inhibitors increase baculovirus-mediated gene expression in mammalian cells when applied before infection.
    Analytical biochemistry, 2010, Jan-15, Volume: 396, Issue:2

    Topics: Animals; Azacitidine; Baculoviridae; Cell Line; CHO Cells; Cricetinae; Cricetulus; Cytosine; Decitabine; DNA (Cytosine-5-)-Methyltransferases; Enzyme Inhibitors; Gene Expression Regulation; Genetic Vectors; Humans

2010
Assessing the DNA methylation status of single cells with the comet assay.
    Analytical biochemistry, 2010, May-15, Volume: 400, Issue:2

    Topics: Azacitidine; Comet Assay; Cytosine; Deoxyribonuclease HpaII; DNA Methylation; DNA-Cytosine Methylases; Hep G2 Cells; Heptanoates; Humans; Tyrosinemias

2010
Measuring topology of low-intensity DNA methylation sites for high-throughput assessment of epigenetic drug-induced effects in cancer cells.
    Experimental cell research, 2010, Nov-15, Volume: 316, Issue:19

    Topics: Antineoplastic Agents; Azacitidine; Cell Line, Tumor; Cell Nucleus; Cytidine; Cytosine; DNA Methylation; DNA, Neoplasm; Epigenesis, Genetic; Fluorescence; High-Throughput Screening Assays; Humans; Indoles; Neoplasms; Nucleic Acid Conformation

2010
Novel agents for the treatment of acute myeloid leukemia in the older patient.
    Journal of the National Comprehensive Cancer Network : JNCCN, 2011, Volume: 9, Issue:3

    Topics: Adenine Nucleotides; Age Factors; Aged; Antineoplastic Agents; Arabinonucleosides; Azacitidine; Clofarabine; Cytosine; Decitabine; Disease-Free Survival; Hematopoietic Stem Cell Transplantation; Humans; Lenalidomide; Leukemia, Myeloid, Acute; Middle Aged; Prognosis; Quinolones; Thalidomide

2011
Characterizing DNA methyltransferases with an ultrasensitive luciferase-linked continuous assay.
    Analytical chemistry, 2011, Jun-15, Volume: 83, Issue:12

    Topics: Azacitidine; Bacteria; Cytosine; Deoxyadenosines; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Enzyme Assays; Humans; Kinetics; Light; Luciferases; S-Adenosylhomocysteine; S-Adenosylmethionine; Thionucleosides

2011
Cytosine methylation in miR-153 gene promoters increases the expression of holocarboxylase synthetase, thereby increasing the abundance of histone H4 biotinylation marks in HEK-293 human kidney cells.
    The Journal of nutritional biochemistry, 2012, Volume: 23, Issue:6

    Topics: 3' Untranslated Regions; Azacitidine; Binding Sites; Biotinylation; Carbon-Nitrogen Ligases; Cytosine; Decitabine; DNA Methylation; Epigenomics; Gene Expression Regulation; HEK293 Cells; Histones; Humans; Kidney; MicroRNAs; Promoter Regions, Genetic

2012
Induced Pib Expression and Resistance to Magnaporthe grisea are Compromised by Cytosine Demethylation at Critical Promoter Regions in Rice.
    Journal of integrative plant biology, 2011, Volume: 53, Issue:10

    Topics: Azacitidine; Cytosine; Disease Resistance; DNA Methylation; Gene Expression Regulation, Plant; Genes, Plant; Magnaporthe; Oryza; Plant Diseases; Plant Proteins; Promoter Regions, Genetic; Sequence Analysis, DNA

2011
Expression of tyrosine hydroxylase is epigenetically regulated in neural stem cells.
    Biochemical and biophysical research communications, 2011, Nov-04, Volume: 414, Issue:4

    Topics: Azacitidine; Base Sequence; CpG Islands; Cytosine; DNA Methylation; Dopaminergic Neurons; Epigenesis, Genetic; Gene Expression Regulation, Developmental; Humans; Molecular Sequence Data; Neural Stem Cells; Promoter Regions, Genetic; Sequence Analysis, DNA; Tyrosine 3-Monooxygenase

2011
Rapid turnover of DNA methylation in human cells.
    Epigenetics, 2012, Volume: 7, Issue:2

    Topics: Azacitidine; Cell Cycle; Cytosine; DNA; DNA Methylation; Flow Cytometry; Genome, Human; Hep G2 Cells; Humans; Mass Spectrometry

2012
Changes in micro RNA expression in a wild tuber-bearing Solanum species induced by 5-Azacytidine treatment.
    Plant cell reports, 2012, Volume: 31, Issue:8

    Topics: Azacitidine; Cytosine; DNA Methylation; Flowers; Gene Expression Regulation, Plant; Genes, Plant; MicroRNAs; Phenotype; Plant Leaves; Plant Tubers; Solanum; Species Specificity

2012
The dynamic changes of DNA methylation and histone modifications of salt responsive transcription factor genes in soybean.
    PloS one, 2012, Volume: 7, Issue:7

    Topics: Azacitidine; Cytosine; DNA; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Plant; Glycine max; Histones; Oligonucleotide Array Sequence Analysis; Promoter Regions, Genetic; Salts; Sequence Analysis, DNA; Thymine; Transcription Factors; Transcriptional Activation

2012
Cytosine methylation and hydroxymethylation mark DNA for elimination in Oxytricha trifallax.
    Genome biology, 2012, Oct-17, Volume: 13, Issue:10

    Topics: Azacitidine; Cytosine; Decitabine; DNA Methylation; DNA, Protozoan; Enzyme Inhibitors; Gene Rearrangement; High-Throughput Nucleotide Sequencing; Mass Spectrometry; Molecular Sequence Data; Oxytricha; Sequence Analysis, DNA

2012
Differences in the methylation patterns of the VaSTS1 and VaSTS10 genes of Vitis amurensis Rupr.
    Biotechnology letters, 2013, Volume: 35, Issue:9

    Topics: Acyltransferases; Azacitidine; Cytosine; DNA Methylation; DNA, Plant; Epigenesis, Genetic; Gene Expression Regulation, Plant; Genes, Plant; Resveratrol; Stilbenes; Vitis

2013
Aldosterone reprograms promoter methylation to regulate αENaC transcription in the collecting duct.
    American journal of physiology. Renal physiology, 2013, Oct-01, Volume: 305, Issue:7

    Topics: Aldosterone; Animals; Azacitidine; Cell Line; Cells, Cultured; Cytosine; Decitabine; Dioxygenases; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3B; DNA-Binding Proteins; Endodeoxyribonucleases; Epithelial Sodium Channels; Kidney Tubules, Collecting; Mice; Promoter Regions, Genetic; Proto-Oncogene Proteins; Sp1 Transcription Factor; Transcription, Genetic

2013
Real-time dynamics of methyl-CpG-binding domain protein 3 and its role in DNA demethylation by fluorescence correlation spectroscopy.
    Epigenetics, 2013, Volume: 8, Issue:10

    Topics: 5-Methylcytosine; Azacitidine; Cell Hypoxia; Cytosine; Decitabine; DNA; DNA Modification Methylases; DNA-Binding Proteins; HeLa Cells; Humans; Single-Cell Analysis; Spectrometry, Fluorescence

2013
Effects of chromatin decondensation on alternative NHEJ.
    DNA repair, 2013, Volume: 12, Issue:11

    Topics: Animals; Azacitidine; Cell Cycle; Cell Line; Chromatin; Chromosomal Instability; Cytosine; Decitabine; DNA Breaks, Double-Stranded; DNA End-Joining Repair; DNA Ligases; DNA Methylation; Gene Expression Regulation; Humans; Hypotonic Solutions; Mice; Translocation, Genetic

2013
Cytosine DNA methylation influences drug resistance in Escherichia coli through increased sugE expression.
    FEMS microbiology letters, 2014, Volume: 350, Issue:1

    Topics: 5-Methylcytosine; Azacitidine; Bacterial Proteins; Cytosine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Drug Resistance, Bacterial; Enzyme Inhibitors; Escherichia coli; Escherichia coli Proteins; Ethidium; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Gene Knockout Techniques; Membrane Proteins; Microbial Sensitivity Tests; Molecular Chaperones; Sigma Factor

2014
Transcriptome-wide target profiling of RNA cytosine methyltransferases using the mechanism-based enrichment procedure Aza-IP.
    Nature protocols, 2014, Volume: 9, Issue:2

    Topics: Azacitidine; Cytosine; Gene Expression Profiling; High-Throughput Nucleotide Sequencing; Humans; Immunoprecipitation; tRNA Methyltransferases

2014
The role of gene body cytosine modifications in MGMT expression and sensitivity to temozolomide.
    Molecular cancer therapeutics, 2014, Volume: 13, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Azacitidine; Cell Line, Tumor; CpG Islands; Cytosine; Dacarbazine; Decitabine; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Quantitative Trait Loci; Temozolomide; Tumor Suppressor Proteins

2014
Trace analysis of methylated and hydroxymethylated cytosines in DNA by isotope-dilution LC-MS/MS: first evidence of DNA methylation in Caenorhabditis elegans.
    The Biochemical journal, 2015, Jan-01, Volume: 465, Issue:1

    Topics: 5-Methylcytosine; Animals; Azacitidine; Cadmium; Caenorhabditis elegans; Chromatography, Liquid; Cytosine; Decitabine; Deoxycytidine; DNA; DNA Methylation; Isotope Labeling; Online Systems; Reproducibility of Results; Solid Phase Extraction; Tandem Mass Spectrometry

2015
The hypomethylating agent Decitabine causes a paradoxical increase in 5-hydroxymethylcytosine in human leukemia cells.
    Scientific reports, 2015, Apr-22, Volume: 5

    Topics: 5-Methylcytosine; Azacitidine; Catalytic Domain; Chromatography, High Pressure Liquid; CpG Islands; Cytosine; Decitabine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA-Binding Proteins; Enzyme-Linked Immunosorbent Assay; HL-60 Cells; Humans; Immunohistochemistry; Leukemia, Myeloid, Acute; MCF-7 Cells; Microscopy, Fluorescence; Mixed Function Oxygenases; Protein Binding; Proto-Oncogene Proteins; Spectrometry, Fluorescence; Tandem Mass Spectrometry

2015
Hydroxymethylcytosine and demethylation of the γ-globin gene promoter during erythroid differentiation.
    Epigenetics, 2015, Volume: 10, Issue:5

    Topics: 5-Methylcytosine; Animals; Animals, Newborn; Antineoplastic Agents; Ascorbic Acid; Azacitidine; Bone Marrow Cells; Cell Differentiation; Cells, Cultured; Cytosine; Decitabine; Dioxygenases; DNA Methylation; Erythroid Cells; gamma-Globins; Histone Demethylases; Humans; Hydroxyurea; Liver; Papio anubis; Promoter Regions, Genetic; Tranylcypromine

2015
5-azacytidine induces transcriptome changes in Escherichia coli via DNA methylation-dependent and DNA methylation-independent mechanisms.
    BMC microbiology, 2016, 06-27, Volume: 16, Issue:1

    Topics: 5-Methylcytosine; Azacitidine; Base Sequence; Cell Culture Techniques; Cytosine; DNA Methylation; DNA, Bacterial; Escherichia coli K12; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Gene Knockout Techniques; Genes, Bacterial; Oligonucleotide Array Sequence Analysis; Polymerase Chain Reaction; RNA, Bacterial; Sequence Analysis; Transcriptome; Up-Regulation

2016
Two-color fluorescent cytosine extension assay for the determination of global DNA methylation.
    BioTechniques, 2017, 04-01, Volume: 62, Issue:4

    Topics: Azacitidine; Biological Assay; Cytosine; Decitabine; DNA Methylation; DNA Restriction Enzymes; Fluorescence; Hep G2 Cells; Humans; Liver; Primary Cell Culture

2017
Characterization of Cytosine Methylation and the DNA Methyltransferases of
    International journal of biological sciences, 2017, Volume: 13, Issue:4

    Topics: Azacitidine; Cytosine; DNA Methylation; Methyltransferases; Toxoplasma

2017
Aberrant DNA methylation of mTOR pathway genes promotes inflammatory activation of immune cells in diabetic kidney disease.
    Kidney international, 2019, Volume: 96, Issue:2

    Topics: Adolescent; Adoptive Transfer; Adult; Aged; Animals; Azacitidine; Cytosine; Diabetic Nephropathies; Disease Models, Animal; Disease Progression; DNA (Cytosine-5-)-Methyltransferase 1; DNA Methylation; Epigenesis, Genetic; Female; Gene Knockdown Techniques; Humans; Leukocytes, Mononuclear; Male; Mice; Middle Aged; Primary Cell Culture; Promoter Regions, Genetic; Signal Transduction; TOR Serine-Threonine Kinases; Up-Regulation; Young Adult

2019
Insights into the Inhibitory Mechanisms of the Covalent Drugs for DNMT3A.
    International journal of molecular sciences, 2023, Aug-10, Volume: 24, Issue:16

    Topics: Azacitidine; Catalysis; Cytosine; DNA Methyltransferase 3A; DNA Modification Methylases

2023