azacitidine and camptothecin

azacitidine has been researched along with camptothecin in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19902 (8.00)18.7374
1990's6 (24.00)18.2507
2000's6 (24.00)29.6817
2010's11 (44.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Abbruzzese, JL; Anzai, H; Frost, P1
Tobey, RA1
Gang, M; Kline, I; Sirica, AE; Venditti, JM; Woodman, RJ1
Darzynkiewicz, Z; Del Bino, G; Li, X; Traganos, F1
Bhatia, U; Darzynkiewicz, Z; Traganos, F1
Bruno, S; Darzynkiewicz, Z; Gong, J; Halicka, HD; Hara, S; Traganos, F1
Ayabe, H; Darzynkiwicz, Z; Hara, S; Tagawa, Y1
Cortés, F; López-Baena, M; Mateos, S; Piñero, J1
Bernard, O; Gagnon, JF; Guillemette, C; Têtu, B; Villeneuve, L1
Enomoto, M; Iida, S; Ishiguro, M; Kato, K; Makino, H; Morita, S; Sugihara, K; Takagi, Y; Uetake, H1
Cortés, F; Mateos, S; Orta, ML1
Ding, L; Guo, B; Qiu, L; Zhang, J1
Cortesi, F; Crea, F; Danesi, R; Del Tacca, M; Gallegos Ruiz, MI; Giovannetti, E; Mey, V; Nannizzi, S; Peters, GJ; Ricciardi, S1
Bai, T; Kobayashi, A; Matsuoka, T; Sasaki, N; Tanaka, J; Tanaka, T; Tanizaki, Y; Toujima, S; Utsunomiya, H; Utsunomiya, T; Yamamoto, M; Yukawa, K1
Aoki, D; Banno, K; Kisu, I; Kobayashi, Y; Masuda, K; Nomura, H; Susumu, N; Tominaga, E; Tsuji, K; Ueki, A; Yamagami, W; Yanokura, M1
Kiianitsa, K; Maizels, N1
Ikehata, M; Iwakawa, S; Ogawa, M; Tanaka, S; Ueda, K; Yamada, Y1
Ang, WT; Ho, GH; Koh, QM; Koong, HN; Lin, VC; Sivaramakrishnan, G; Sun, Y1
Baylin, SB; Dobromilskaya, I; Easwaran, H; Huang, P; Poirier, JT; Rudin, CM; Topper, M; Vendetti, FP; Wrangle, J1
Jadhav, SS; Kumara, PM; Manjunatha, BL; Nataraja, KN; Ravikanth, G; Sachin, N; Shweta, S; Uma Shaanker, R; Vasanthakumari, MM; Vinod, G1
A Guzzetta, A; Abdelfatah, E; Ahuja, N; Azad, N; B Baylin, S; Hu, Y; Kerner, Z; Sharma, A; Singh, J; Vatapalli, R; Wyatt McMahon, K; Yerram, S; Zahnow, C1
Fukuda, M; Hosokawa, M; Iwakawa, S; Masuda, A; Tanaka, S; Ueda, K1
Alla, R; Ayyadevara, S; Fedichev, PO; Menshikov, LI; Pyatnitskiy, M; Shmookler Reis, RJ; Tarkhov, AE1

Other Studies

25 other study(ies) available for azacitidine and camptothecin

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Synergistic cytotoxicity with 2'-deoxy-5-azacytidine and topotecan in vitro and in vivo.
    Cancer research, 1992, Apr-15, Volume: 52, Issue:8

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Azacitidine; Camptothecin; Colorectal Neoplasms; Decitabine; DNA Topoisomerases, Type I; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Drug Synergism; Female; Lethal Dose 50; Methylation; Mice; Mice, Inbred BALB C; Topotecan; Tumor Cells, Cultured

1992
Effects of cytosine arabinoside, daunomycin, mithramycin, azacytidine, adriamycin, and camptothecin on mammalian cell cycle traverse.
    Cancer research, 1972, Volume: 32, Issue:12

    Topics: Animals; Antineoplastic Agents; Autoradiography; Azacitidine; Camptothecin; Cell Division; Cell Line; Cricetinae; Cytarabine; Daunorubicin; DNA; DNA Replication; Doxorubicin; Mitosis; Plicamycin; Thymidine; Tritium

1972
The enhanced therapeutic effect of cis-platinum (II) diamminodichloride against L1210 leukemia when combined with cyclophosphamide or 1,2-bis(3,5-dioxopiperazine-1-yl)propane or several other antitumor agents.
    Chemotherapy, 1973, Volume: 18, Issue:3

    Topics: Amines; Animals; Antineoplastic Agents; Azacitidine; Camptothecin; Carmustine; Chlorides; Cyclophosphamide; Cytarabine; Drug Synergism; Emetine; Fluorouracil; Ketones; Leukemia L1210; Male; Methotrexate; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Piperazines; Platinum; Propane; Time Factors

1973
Altered susceptibility of differentiating HL-60 cells to apoptosis induced by antitumor drugs.
    Leukemia, 1994, Volume: 8, Issue:2

    Topics: Antineoplastic Agents; Apoptosis; Azacitidine; Camptothecin; Cell Cycle; Cell Differentiation; Dimethyl Sulfoxide; DNA, Neoplasm; Humans; Hyperthermia, Induced; Leukemia, Promyelocytic, Acute; Nuclear Proteins; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Tumor Cells, Cultured

1994
Induction of cell differentiation potentiates apoptosis triggered by prior exposure to DNA-damaging drugs.
    Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 1995, Volume: 6, Issue:8

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Apoptosis; Azacitidine; Butyrates; Butyric Acid; Camptothecin; Cell Differentiation; DNA Damage; Enzyme Inhibitors; Humans; Mechlorethamine; Topoisomerase I Inhibitors; Tumor Cells, Cultured

1995
Effect of protease inhibitors on early events of apoptosis.
    Experimental cell research, 1996, Mar-15, Volume: 223, Issue:2

    Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Camptothecin; Chromatin; DNA; Endonucleases; Enzyme Inhibitors; Glucocorticoids; HL-60 Cells; Humans; Molecular Weight; Prednisolone; Rats; Rats, Sprague-Dawley; Serine Proteinase Inhibitors; Thymus Gland; Topoisomerase I Inhibitors

1996
[Analysis of drug-induced apoptosis in human leukemic cell line (HL-60)].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1998, Volume: 25 Suppl 3

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Apoptosis; Azacitidine; Camptothecin; Cell Cycle; HL-60 Cells; Humans; Leukemia, Promyelocytic, Acute; Tosylphenylalanyl Chloromethyl Ketone

1998
Enhanced sensitivity to topoisomerase inhibitors in synchronous CHO cells pre-treated with 5-azacytidine.
    Mutation research, 1998, Oct-12, Volume: 421, Issue:1

    Topics: Amsacrine; Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Azacitidine; Camptothecin; CHO Cells; Chromosome Aberrations; Cricetinae; DNA Methylation; Drug Interactions; Enzyme Inhibitors; S Phase; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors

1998
Irinotecan inactivation is modulated by epigenetic silencing of UGT1A1 in colon cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2006, Mar-15, Volume: 12, Issue:6

    Topics: Azacitidine; Camptothecin; Cell Line, Tumor; CpG Islands; Decitabine; DNA Methylation; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Glucuronides; Glucuronosyltransferase; HCT116 Cells; HT29 Cells; Humans; Hydroxamic Acids; Irinotecan

2006
Effect of combined therapy with low-dose 5-aza-2'-deoxycytidine and irinotecan on colon cancer cell line HCT-15.
    Annals of surgical oncology, 2007, Volume: 14, Issue:5

    Topics: Adaptor Proteins, Signal Transducing; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptosis Regulatory Proteins; Azacitidine; Camptothecin; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Cyclin-Dependent Kinase Inhibitor p16; Decitabine; DNA Methylation; Drug Therapy, Combination; Gene Expression Regulation, Neoplastic; Humans; In Situ Nick-End Labeling; Intracellular Signaling Peptides and Proteins; Irinotecan; Male; Membrane Proteins; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Proteins; Promoter Regions, Genetic; Proto-Oncogene Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Survival Rate; Tumor Suppressor Protein p14ARF

2007
DNA demethylation protects from cleavable complex stabilization and DNA strand breakage induced by the topoisomerase type I inhibitor camptothecin.
    Mutagenesis, 2009, Volume: 24, Issue:3

    Topics: Animals; Azacitidine; Camptothecin; CHO Cells; Comet Assay; Cricetinae; Cricetulus; Decitabine; DNA Breaks; DNA Methylation; DNA Topoisomerases, Type I; Electrophoresis, Gel, Pulsed-Field; Enzyme Inhibitors; Epigenesis, Genetic; Topoisomerase I Inhibitors

2009
Camptothecin-induced cell proliferation inhibition and apoptosis enhanced by DNA methyltransferase inhibitor, 5-aza-2'-deoxycytidine.
    Biological & pharmaceutical bulletin, 2009, Volume: 32, Issue:6

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Azacitidine; Camptothecin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Decitabine; DNA (Cytosine-5-)-Methyltransferases; Drug Synergism; Electrophoresis, Gel, Two-Dimensional; Enzyme-Linked Immunosorbent Assay; Galectin 1; Humans; Reverse Transcriptase Polymerase Chain Reaction; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2009
Epigenetic mechanisms of irinotecan sensitivity in colorectal cancer cell lines.
    Molecular cancer therapeutics, 2009, Volume: 8, Issue:7

    Topics: 14-3-3 Proteins; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Apoptosis; Azacitidine; Camptothecin; Cell Cycle; Cell Proliferation; Colorectal Neoplasms; Cyclin-Dependent Kinase Inhibitor p16; DNA Damage; DNA Methylation; DNA Topoisomerases, Type I; Drug Therapy, Combination; Epigenesis, Genetic; Humans; Irinotecan; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2009
Demethylation restores SN38 sensitivity in cells with acquired resistance to SN38 derived from human cervical squamous cancer cells.
    Oncology reports, 2012, Volume: 27, Issue:4

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis Regulatory Proteins; Azacitidine; Calcium-Calmodulin-Dependent Protein Kinases; Camptothecin; Carcinoma, Squamous Cell; Cell Line, Tumor; Cisplatin; Dealkylation; Death-Associated Protein Kinases; Decitabine; DNA Modification Methylases; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Enzyme Inhibitors; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Irinotecan; Promoter Regions, Genetic; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transcription, Genetic; Uterine Cervical Neoplasms

2012
Association of epigenetic inactivation of the WRN gene with anticancer drug sensitivity in cervical cancer cells.
    Oncology reports, 2012, Volume: 28, Issue:4

    Topics: Adenocarcinoma; Antineoplastic Agents; Azacitidine; Camptothecin; Carcinoma, Squamous Cell; Cell Line, Tumor; Decitabine; DNA Methylation; Epigenesis, Genetic; Exodeoxyribonucleases; Female; Gene Expression Regulation, Neoplastic; Humans; Irinotecan; RecQ Helicases; RNA, Small Interfering; Topoisomerase I Inhibitors; Uterine Cervical Neoplasms; Werner Syndrome Helicase

2012
A rapid and sensitive assay for DNA-protein covalent complexes in living cells.
    Nucleic acids research, 2013, Volume: 41, Issue:9

    Topics: Azacitidine; Camptothecin; Cell Line; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Adducts; DNA Topoisomerases, Type I; DNA-Binding Proteins; Humans; Immunoassay; Nuclear Proteins; Topoisomerase I Inhibitors

2013
Different effects of epigenetic modifiers on the cytotoxicity induced by 5-fluorouracil, irinotecan or oxaliplatin in colon cancer cells.
    Biological & pharmaceutical bulletin, 2014, Volume: 37, Issue:1

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Camptothecin; Cell Line, Tumor; Colonic Neoplasms; Decitabine; DNA; DNA Modification Methylases; Drug Synergism; Epigenesis, Genetic; Fluorouracil; HCT116 Cells; Histone Deacetylase Inhibitors; HT29 Cells; Humans; Irinotecan; Organoplatinum Compounds; Oxaliplatin

2014
Down-regulation of tripartite-motif containing 22 expression in breast cancer is associated with a lack of p53-mediated induction.
    Biochemical and biophysical research communications, 2013, Nov-22, Volume: 441, Issue:3

    Topics: Antineoplastic Agents; Azacitidine; Breast Neoplasms; Camptothecin; DNA Damage; DNA Methylation; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; HeLa Cells; Humans; MCF-7 Cells; Minor Histocompatibility Antigens; Paclitaxel; Promoter Regions, Genetic; Repressor Proteins; Topoisomerase I Inhibitors; Tripartite Motif Proteins; Tubulin Modulators; Tumor Suppressor Protein p53

2013
Evaluation of azacitidine and entinostat as sensitization agents to cytotoxic chemotherapy in preclinical models of non-small cell lung cancer.
    Oncotarget, 2015, Jan-01, Volume: 6, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Benzamides; Camptothecin; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Survival; DNA Methylation; Drug Evaluation, Preclinical; Epigenesis, Genetic; Female; Histones; Humans; Irinotecan; Lung Neoplasms; Mice; Mice, Inbred NOD; Mice, SCID; Neoplasm Transplantation; Pyridines

2015
Restoration of camptothecine production in attenuated endophytic fungus on re-inoculation into host plant and treatment with DNA methyltransferase inhibitor.
    World journal of microbiology & biotechnology, 2015, Volume: 31, Issue:10

    Topics: Azacitidine; Camptothecin; Endophytes; Enzyme Inhibitors; Epigenesis, Genetic; Fungi; Magnoliopsida; Methyltransferases; Secondary Metabolism

2015
Hypomethylating agents synergize with irinotecan to improve response to chemotherapy in colorectal cancer cells.
    PloS one, 2017, Volume: 12, Issue:4

    Topics: Animals; Antineoplastic Agents; ATP-Binding Cassette Transporters; Azacitidine; Caco-2 Cells; Camptothecin; Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; DNA Methylation; DNA Repair; Gene Expression; Gene Expression Profiling; HCT116 Cells; Humans; Irinotecan; Long Interspersed Nucleotide Elements; Mice; Mice, Inbred NOD; Mice, SCID

2017
Monophosphorylation by deoxycytidine kinase affects apparent cellular uptake of decitabine in HCT116 colon cancer cells.
    Drug metabolism and pharmacokinetics, 2017, Volume: 32, Issue:6

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Camptothecin; Colonic Neoplasms; Cytarabine; Decitabine; Deoxycytidine; Deoxycytidine Kinase; Equilibrative Nucleoside Transporter 1; Etoposide; Gemcitabine; HCT116 Cells; Humans; Irinotecan; Phosphorylation

2017
A universal transcriptomic signature of age reveals the temporal scaling of Caenorhabditis elegans aging trajectories.
    Scientific reports, 2019, 05-14, Volume: 9, Issue:1

    Topics: Animals; Anisomycin; Azacitidine; Benzazepines; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Camptothecin; Datasets as Topic; Dipyrone; Dose-Response Relationship, Drug; Gene Regulatory Networks; Indoles; Kaplan-Meier Estimate; Longevity; Models, Animal; RNA-Seq; Time Factors; Transcriptome

2019
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