azacitidine and adenosine

azacitidine has been researched along with adenosine in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19909 (32.14)18.7374
1990's2 (7.14)18.2507
2000's4 (14.29)29.6817
2010's12 (42.86)24.3611
2020's1 (3.57)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Bloch, A1
Ng, SK; Rogers, J; Sanwal, BD1
Daino, L; Feo, F; Lai, P; Pascale, R; Ruggiu, ME; Satta, G; Seddaiu, MA; Sequenza, MJ; Simile, MM; Vannini, MG1
Cihák, A; Hovi, T; Raivio, KO1
Cox, R1
Doskocil, J1
Abbasi, MM; Beisler, JA; Glazer, RI; Peale, AL1
Glazer, RI; Lin, HL1
Adams, JK; Allan, RG; Cooper, IA; Woodcock, DM1
Hoffman, RM1
Barbés, C; Fernandez, M; Novella, IS; Sánchez, J; Soliveri, J; Yebra, MJ1
Chan, MT; Cheyette, BN; Jiang, X; Kivimäe, S; Lee, PL; Li, J; Liu, ET; Stanton, LW; Tan, J; Yang, X; Yu, Q; Zhuang, L1
Abe, M; Cortez, CC; Jones, PA; Kelly, TK; Liang, G; Marquez, VE; Miranda, TB; Yoo, CB1
Blom, HJ; de Groot, LC; Lute, C; Mathers, JC; Müller, M; Piek, E; Steegenga, WT; Vaes, BL; van der Woning, SP; Vermeer, J1
Chan, E; Marquez, VE; Sun, F; Wu, Z; Yang, X; Yu, Q1
Boison, D; Farrell, JM; Kaplan, DL; Lusardi, TA; Lytle, NK; Pritchard, EM; Sandau, US; Williams-Karnesky, RL1
Arora, A; Bhushan, A; Gautam, L; Kaur, P; Kumar, A; Sharma, P; Sharma, S; Singh, A; Singh, TP; Sinha, M1
Borchardt, C; Clemens, D; Dirksen, U; Frühwald, MC; Kool, M; Unland, R1
Han, L; Jiang, K; Kang, C; Liu, X; Ning, X; Shi, Z; Zhang, A; Zhang, Q1
Chen, RP; Deng, W; Guo, YT; Li, R; Liu, LX; Pu, ZJ; Wang, GF; Wu, LF; Xiang, MQ; Zhou, XT1
Clemens, D; Dirksen, U; Hotfilder, M; Klco-Brosius, S; Pettke, A; Potratz, J; Schaefer, C1
Brand, OJ; Jenkins, G; Knox, AJ; Pang, L; Pasini, A1
Dvořák Tomaštíková, E; Ercan, U; Finke, A; Krečmerová, M; Niezgodzki, I; Nowicka, A; Otmar, M; Pecinka, A; Poppenberger, B; Procházková, K; Rozhon, W; Schubert, I; Tokarz, B; Zwyrtková, J1

Reviews

3 review(s) available for azacitidine and adenosine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
The structure of nucleosides in relation to their biological and and biochemical activity: a summary.
    Annals of the New York Academy of Sciences, 1975, Aug-08, Volume: 255

    Topics: 3-Deazauridine; Adenine; Adenosine; Anti-Bacterial Agents; Azacitidine; Cytarabine; Idoxuridine; Isopentenyladenosine; Nucleosides; Pseudouridine; Puromycin; Structure-Activity Relationship; Tubercidin; Uridine

1975
Altered methionine metabolism, DNA methylation and oncogene expression in carcinogenesis. A review and synthesis.
    Biochimica et biophysica acta, 1984, Volume: 738, Issue:1-2

    Topics: Adenosine; Animals; Azacitidine; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Choline; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA, Viral; Ethionine; Gene Expression Regulation; Homocysteine; Humans; Methionine; Methylation; Methyltransferases; Neoplasms; Oncogenes; Oncogenic Viruses; S-Adenosylhomocysteine; S-Adenosylmethionine; Simian virus 40

1984

Other Studies

25 other study(ies) available for azacitidine and adenosine

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Alterations in differentiation and pyrimidine pathway enzymes in 5-azacytidine resistant variants of a myoblast line.
    Journal of cellular physiology, 1977, Volume: 90, Issue:2

    Topics: Adenosine; Animals; Aspartate Carbamoyltransferase; Azacitidine; Azaguanine; Bromodeoxyuridine; Cell Differentiation; Cell Fusion; Cell Line; Cytarabine; Cytidine Deaminase; Drug Resistance; Genetic Variation; Muscles; Nucleoside Deaminases; Orotate Phosphoribosyltransferase; Orotidine-5'-Phosphate Decarboxylase; Ouabain; Phosphotransferases; Rats; Theophylline; Thymidine; Uridine; Uridine Kinase

1977
Reversal by 5-azacytidine of the S-adenosyl-L-methionine-induced inhibition of the development of putative preneoplastic foci in rat liver carcinogenesis.
    Cancer letters, 1991, Volume: 56, Issue:3

    Topics: Adenosine; Animals; Azacitidine; Biomarkers, Tumor; Deoxyadenosines; Diethylnitrosamine; gamma-Glutamyltransferase; Liver; Liver Neoplasms, Experimental; Male; Precancerous Conditions; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Thionucleosides

1991
Inhibition of phytohemagglutinin-induced DNA synthesis and of adenosine deamination by 5-azacytidine and 5-aza-2'-deoxycytidine in intact human cells.
    Neoplasma, 1985, Volume: 32, Issue:3

    Topics: Adenosine; Antineoplastic Agents; Azacitidine; Cells, Cultured; Deamination; Decitabine; DNA; Humans; Lymphocytes; Phytohemagglutinins

1985
Studies on DNA methyltransferase and alteration of the enzyme activity by chemical carcinogens.
    Toxicologic pathology, 1986, Volume: 14, Issue:4

    Topics: Adenosine; Adenosine Triphosphate; Alkylation; Animals; Azacitidine; Carcinogens; DNA; DNA (Cytosine-5-)-Methyltransferases; Ethionine; Male; Methylnitrosourea; Rats; Rats, Inbred Strains; Selenium

1986
The components of the nucleoside-transporting system in Escherichia coli.
    Biochimica et biophysica acta, 1972, Sep-01, Volume: 282, Issue:1

    Topics: Adenosine; Azacitidine; Biological Transport; Carbon Isotopes; Cell Membrane; Coliphages; Cytidine; Deamination; Deoxyadenosines; Drug Resistance, Microbial; Escherichia coli; Kinetics; Mutation; Nucleosides; Osmosis; Phosphoric Acids; Thymidine; Tritium

1972
The effect of 5-azacytidine and dihydro-5-azacytidine on nuclear ribosomal RNA and poly(A) RNA synthesis in L1210 cells in vitro.
    Molecular pharmacology, 1980, Volume: 17, Issue:1

    Topics: Adenosine; Animals; Azacitidine; Cells, Cultured; Depression, Chemical; Dose-Response Relationship, Drug; Leukemia L1210; Methionine; Methylation; Mice; Poly A; RNA; RNA, Heterogeneous Nuclear; RNA, Messenger; RNA, Ribosomal; Uridine

1980
The comparative effects of 5-azacytidine and dihydro-5-azacytidine on polysomal RNA in Ehrlich ascites cells in vitro.
    Molecular pharmacology, 1981, Volume: 20, Issue:3

    Topics: Adenosine; Animals; Azacitidine; Carcinoma, Ehrlich Tumor; Mice; Polyribosomes; Protein Biosynthesis; Reticulocytes; RNA, Neoplasm; RNA, Ribosomal

1981
Effect of several inhibitors of enzymatic DNA methylation on the in vivo methylation of different classes of DNA sequences in a cultured human cell line.
    Nucleic acids research, 1983, Jan-25, Volume: 11, Issue:2

    Topics: 5-Methylcytosine; Adenosine; Azacitidine; Brain Neoplasms; Cell Division; Cell Line; Cycloleucine; Cytosine; Deoxyadenosines; DNA; DNA Replication; Ethionine; Homocysteine; Humans; Methylation; Thionucleosides; Tubercidin

1983
Effect of 5-azacytidine and sinefungin on Streptomyces development.
    Gene, 1995, May-19, Volume: 157, Issue:1-2

    Topics: Adenosine; Anti-Bacterial Agents; Antifungal Agents; Azacitidine; Bacterial Proteins; DNA-Binding Proteins; Gene Expression Regulation, Bacterial; Genes, Bacterial; Sigma Factor; Spores, Bacterial; Streptomyces; Streptomyces antibioticus; Transcription Factors

1995
DACT3 is an epigenetic regulator of Wnt/beta-catenin signaling in colorectal cancer and is a therapeutic target of histone modifications.
    Cancer cell, 2008, Volume: 13, Issue:6

    Topics: Adaptor Proteins, Signal Transducing; Adenosine; Adenosylhomocysteinase; Apoptosis; Azacitidine; beta Catenin; Colorectal Neoplasms; Decitabine; Dishevelled Proteins; DNA Methylation; DNA Modification Methylases; Down-Regulation; Enzyme Inhibitors; Epigenesis, Genetic; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; HCT116 Cells; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Humans; Hydroxamic Acids; Oligonucleotide Array Sequence Analysis; Phosphoproteins; Promoter Regions, Genetic; Reproducibility of Results; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Transfection; Wnt Proteins

2008
DZNep is a global histone methylation inhibitor that reactivates developmental genes not silenced by DNA methylation.
    Molecular cancer therapeutics, 2009, Volume: 8, Issue:6

    Topics: Adenosine; Azacitidine; Blotting, Western; Cell Line; Cell Line, Tumor; Decitabine; DNA Methylation; DNA-Binding Proteins; Enhancer of Zeste Homolog 2 Protein; Enzyme Inhibitors; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Histones; Humans; Keratin-7; Methylation; Molecular Structure; Oligonucleotide Array Sequence Analysis; Polycomb Repressive Complex 2; Reverse Transcriptase Polymerase Chain Reaction; Transcription Factors

2009
Inhibition of methylation decreases osteoblast differentiation via a non-DNA-dependent methylation mechanism.
    Bone, 2010, Volume: 46, Issue:2

    Topics: Adenosine; Alkaline Phosphatase; Animals; Azacitidine; Cell Differentiation; Cell Line; Core Binding Factor Alpha 1 Subunit; DNA Methylation; Humans; Mice; Organ Specificity; Osteoblasts; Osteogenesis; Transcriptional Activation

2010
Combinatorial pharmacologic approaches target EZH2-mediated gene repression in breast cancer cells.
    Molecular cancer therapeutics, 2009, Volume: 8, Issue:12

    Topics: Adenosine; Antigens, Neoplasm; Azacitidine; Breast Neoplasms; Cell Line; Cell Line, Tumor; Chromatin Immunoprecipitation; Cluster Analysis; CpG Islands; Decitabine; DNA Methylation; DNA-Binding Proteins; Enhancer of Zeste Homolog 2 Protein; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Immunoblotting; Methylation; Neoplasm Proteins; Oligonucleotide Array Sequence Analysis; Polycomb Repressive Complex 2; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Transcription Factors

2009
Epigenetic changes induced by adenosine augmentation therapy prevent epileptogenesis.
    The Journal of clinical investigation, 2013, Volume: 123, Issue:8

    Topics: Adenosine; Adenosine Kinase; Animals; Anticonvulsants; Azacitidine; Base Sequence; Brain; CpG Islands; Decitabine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Drug Implants; Epigenesis, Genetic; Epilepsy; Male; Mice; Mossy Fibers, Hippocampal; Rats; Rats, Sprague-Dawley; Sequence Analysis, DNA

2013
Structural and binding studies of peptidyl-tRNA hydrolase from Pseudomonas aeruginosa provide a platform for the structure-based inhibitor design against peptidyl-tRNA hydrolase.
    The Biochemical journal, 2014, Nov-01, Volume: 463, Issue:3

    Topics: Adenosine; Azacitidine; Bacterial Proteins; Carboxylic Ester Hydrolases; Catalytic Domain; Crystallography, X-Ray; Drug Design; Enzyme Inhibitors; Hydrogen Bonding; Protein Conformation; Pseudomonas aeruginosa; Structure-Activity Relationship; Tyrosine

2014
Analysis of the antiproliferative effects of 3-deazaneoplanocin A in combination with standard anticancer agents in rhabdoid tumor cell lines.
    Anti-cancer drugs, 2015, Volume: 26, Issue:3

    Topics: Adenosine; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Azacitidine; Cell Line, Tumor; Cell Proliferation; Decitabine; Doxorubicin; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Etoposide; Gene Expression Regulation, Neoplastic; Humans; Hydroxamic Acids; Molecular Targeted Therapy; Polycomb Repressive Complex 2; Rhabdoid Tumor; Vorinostat

2015
DNMT1 and EZH2 mediated methylation silences the microRNA-200b/a/429 gene and promotes tumor progression.
    Cancer letters, 2015, Apr-10, Volume: 359, Issue:2

    Topics: Adenosine; Animals; Antineoplastic Agents; Azacitidine; Cell Line, Tumor; Decitabine; Disease Progression; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Enhancer of Zeste Homolog 2 Protein; Gene Expression Regulation, Neoplastic; Gene Silencing; Glioblastoma; Histones; Humans; Mice, Inbred BALB C; Mice, Nude; MicroRNAs; Polycomb Repressive Complex 2; Stomach Neoplasms; Tumor Burden; Xenograft Model Antitumor Assays

2015
The mechanism of adenosine-mediated activation of lncRNA MEG3 and its antitumor effects in human hepatoma cells.
    International journal of oncology, 2016, Volume: 48, Issue:1

    Topics: Adenosine; Apoptosis; Azacitidine; Carcinoma, Hepatocellular; Cell Proliferation; CpG Islands; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Liver Neoplasms; Neoplasm Proteins; Promoter Regions, Genetic; RNA, Long Noncoding

2016
Suberanilohydroxamic acid (vorinostat) synergistically enhances the cytotoxicity of doxorubicin and cisplatin in osteosarcoma cell lines.
    Anti-cancer drugs, 2016, Volume: 27, Issue:10

    Topics: Adenosine; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Bone Neoplasms; Cell Growth Processes; Cell Line, Tumor; Cisplatin; Doxorubicin; Drug Synergism; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Osteosarcoma; Vorinostat

2016
Suberanilohydroxamic acid prevents TGF-β1-induced COX-2 repression in human lung fibroblasts post-transcriptionally by TIA-1 downregulation.
    Biochimica et biophysica acta. Gene regulatory mechanisms, 2018, Volume: 1861, Issue:5

    Topics: Adenosine; Azacitidine; Cell Line; Cyclooxygenase 1; Cyclooxygenase 2; Decitabine; DNA Methylation; Enhancer of Zeste Homolog 2 Protein; Fibroblasts; Gene Expression Regulation; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Lung; Promoter Regions, Genetic; T-Cell Intracellular Antigen-1; Transforming Growth Factor beta1; Vorinostat

2018
Comparative analysis of epigenetic inhibitors reveals different degrees of interference with transcriptional gene silencing and induction of DNA damage.
    The Plant journal : for cell and molecular biology, 2020, Volume: 102, Issue:1

    Topics: Adenosine; Arabidopsis; Azacitidine; Chromosome Aberrations; Cytidine; Decitabine; DNA Damage; DNA Methylation; DNA Repair; Epigenesis, Genetic; Gene Silencing; Heterochromatin; RNA Interference; Tandem Repeat Sequences

2020