azacitidine and acetylcysteine

azacitidine has been researched along with acetylcysteine in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19901 (7.14)18.7374
1990's0 (0.00)18.2507
2000's3 (21.43)29.6817
2010's8 (57.14)24.3611
2020's2 (14.29)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Lombardo, F; Obach, RS; Waters, NJ1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Abbott, V; Deloria, LB; Mannering, GJ1
Capanni, C; Columbaro, M; D'Apice, MR; Foisner, R; Lattanzi, G; Maraldi, NM; Mattioli, E; Novelli, G; Riccio, M; Santi, S; Squarzoni, S1
Jung, G; Lim, SO; Quan, X1
Ko, JL; Lee, H; Tang, SC; Wang, PH; Wu, CH1
Choi, YH; Han, MH; Kang, HS; Kim, GY; Kim, WJ; Park, YS; Shin, DY; Yang, K1
Chen, M; Dasgupta, C; Hu, XQ; Xiao, D; Yang, S; Zhang, L1
Cruz, M; Germain, G; Jabeen, S; Javdan, M; Lockshin, RA; Penaloza, CG; Zakeri, Z1

Reviews

1 review(s) available for azacitidine and acetylcysteine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

13 other study(ies) available for azacitidine and acetylcysteine

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Role of xanthine oxidase in the interferon-mediated depression of the hepatic cytochrome P-450 system in mice.
    Cancer research, 1988, Apr-15, Volume: 48, Issue:8

    Topics: Acetylcysteine; Aldehyde Oxidase; Aldehyde Oxidoreductases; Allopurinol; Allylisopropylacetamide; Animals; Azacitidine; Carboxymethylcellulose Sodium; Cytochrome P-450 Enzyme Inhibitors; Dithiothreitol; Ethylmorphine-N-Demethylase; Interferons; Liver; Male; Mice; Phenobarbital; Poly I-C; Polylysine; Tungsten; Tungsten Compounds; Xanthine Dehydrogenase; Xanthine Oxidase

1988
Drugs affecting prelamin A processing: effects on heterochromatin organization.
    Experimental cell research, 2008, Feb-01, Volume: 314, Issue:3

    Topics: Acetylcysteine; Adult; Antimetabolites, Antineoplastic; Azacitidine; Cell Nucleus; Cells, Cultured; Chromatin Assembly and Disassembly; Decitabine; DNA-Binding Proteins; Enzyme Inhibitors; Farnesyltranstransferase; Fibroblasts; Heterochromatin; Humans; Lamin Type A; Membrane Proteins; Methionine; Nuclear Lamina; Nuclear Proteins; Protein Precursors; Protein Prenylation

2008
Reactive oxygen species downregulate catalase expression via methylation of a CpG island in the Oct-1 promoter.
    FEBS letters, 2011, Nov-04, Volume: 585, Issue:21

    Topics: Acetylcysteine; Azacitidine; Carcinoma, Hepatocellular; Catalase; Cell Line, Tumor; CpG Islands; Decitabine; DNA Methylation; Down-Regulation; Enzyme Activation; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Neoplasm Invasiveness; Octamer Transcription Factor-1; Promoter Regions, Genetic; Reactive Oxygen Species

2011
Nickel-induced epithelial-mesenchymal transition by reactive oxygen species generation and E-cadherin promoter hypermethylation.
    The Journal of biological chemistry, 2012, Jul-20, Volume: 287, Issue:30

    Topics: Acetylcysteine; Antigens, Differentiation; Azacitidine; Bronchi; Cadherins; Cell Line, Transformed; Decitabine; DNA Methylation; DNA Modification Methylases; Enzyme Inhibitors; Epithelial Cells; Epithelial-Mesenchymal Transition; Fibronectins; Free Radical Scavengers; Gene Expression Regulation; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Intercellular Junctions; Nickel; Pulmonary Fibrosis; Reactive Oxygen Species; Respiratory Mucosa

2012
Decitabine, a DNA methyltransferase inhibitor, induces apoptosis in human leukemia cells through intracellular reactive oxygen species generation.
    International journal of oncology, 2012, Volume: 41, Issue:3

    Topics: Acetylcysteine; Apoptosis; Azacitidine; Baculoviral IAP Repeat-Containing 3 Protein; Caspases; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Decitabine; Down-Regulation; Enzyme Inhibitors; Humans; Inhibitor of Apoptosis Proteins; Leukemia; Membrane Potential, Mitochondrial; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Ubiquitin-Protein Ligases; X-Linked Inhibitor of Apoptosis Protein

2012
Hypoxia Represses ER-α Expression and Inhibits Estrogen-Induced Regulation of Ca2+-Activated K+ Channel Activity and Myogenic Tone in Ovine Uterine Arteries: Causal Role of DNA Methylation.
    Hypertension (Dallas, Tex. : 1979), 2015, Volume: 66, Issue:1

    Topics: Acetylcysteine; Animals; Azacitidine; Decitabine; DNA Methylation; Estradiol; Estrogen Receptor alpha; Female; Gene Expression Regulation; Hypoxia; Large-Conductance Calcium-Activated Potassium Channel alpha Subunits; Pregnancy; Pregnancy Complications; Progesterone; Promoter Regions, Genetic; Reactive Oxygen Species; Sheep; Uterine Artery; Vascular Resistance

2015
Higher sensitivity of female cells to ethanol: methylation of DNA lowers Cyp2e1, generating more ROS.
    Cell communication and signaling : CCS, 2020, 07-11, Volume: 18, Issue:1

    Topics: Acetylcysteine; Alcohol Dehydrogenase; Aldehyde Dehydrogenase; Animals; Azacitidine; Cell Death; Cell Survival; Cytochrome P-450 CYP2E1; DNA Methylation; Ethanol; Female; Gene Expression Regulation, Enzymologic; Male; Mice; Models, Biological; Protein Isoforms; Reactive Oxygen Species; Sex Characteristics; Stress, Physiological; Transcription, Genetic

2020