avoparcin and maduramicin

The effects of the growth promoters avoparcin and avilamycin and the ionophore anticoccidials maduramicin, narasin and monensin on the growth of Clostridium perfringens (Cp) in the caeca and on performance of broiler chickens were tested in 2 experiments. The supplements were fed as single feed additives or in some combinations. No clinical signs or lesions caused by coccidia were observed in any of the studies. All supplements had an antibacterial effect on Cp and improved growth rate significantly. Carcass yield of birds fed growth promoters avilamycin or avoparcin was significantly higher compared with birds fed anticoccidials. These data indicate that, what concerns bird performance, during good hygienic conditions supplementation with antibiotic growth promoters may not be necessary when the diet is supplemented with an anticoccidial with antibacterial effects.

Topics: Animal Feed; Animals; Anti-Bacterial Agents; Cecum; Chickens; Clostridium Infections; Clostridium perfringens; Coccidiostats; Glycopeptides; Growth Substances; Ionophores; Lactones; Monensin; Oligosaccharides; Poultry Diseases; Pyrans; Random Allocation

1. The anticoccidial activity of maduramicin ammonium (5 mg/kg food) administered alone or with roxarsone (50 mg/kg food) and/or avoparcin (10 mg/kg food) was evaluated in battery-reared broilers artificially challenged with recent field culture mixtures containing Eimeria acervulina, E. maxima and E. tenella or E. mivati, E. necatrix and E. brunetti. 2. Maduramicin ammonium exhibited a high degree of anticoccidial activity and the addition of roxarsone and/or avoparcin in food at recommended concentrations did not adversely affect the activity.

Topics: Animals; Anti-Bacterial Agents; Arsenicals; Chickens; Coccidiosis; Drug Combinations; Drug Evaluation; Glycopeptides; Lactones; Male; Poultry Diseases; Roxarsone