avitriptan has been researched along with sumatriptan in 5 studies
| Studies (avitriptan) | Trials (avitriptan) | Recent Studies (post-2010) (avitriptan) | Studies (sumatriptan) | Trials (sumatriptan) | Recent Studies (post-2010) (sumatriptan) |
|---|---|---|---|---|---|
| 19 | 13 | 1 | 2,405 | 461 | 480 |
| Protein | Taxonomy | avitriptan (IC50) | sumatriptan (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 3E | Homo sapiens (human) | 0.0073 | |
| 5-hydroxytryptamine receptor 3B | Homo sapiens (human) | 0.0073 | |
| 5-hydroxytryptamine receptor 1A | Homo sapiens (human) | 0.4497 | |
| Carboxypeptidase M | Homo sapiens (human) | 0.02 | |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.64 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 0.722 | |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | 0.64 | |
| 5-hydroxytryptamine receptor 1D | Homo sapiens (human) | 0.3091 | |
| 5-hydroxytryptamine receptor 1B | Homo sapiens (human) | 0.0131 | |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | 7.9433 | |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | 3.9753 | |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | 0.804 | |
| 5-hydroxytryptamine receptor 1D | Rattus norvegicus (Norway rat) | 0.061 | |
| 5-hydroxytryptamine receptor 1E | Homo sapiens (human) | 5.5 | |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.64 | |
| 5-hydroxytryptamine receptor 3A | Homo sapiens (human) | 0.0078 | |
| 5-hydroxytryptamine receptor 5A | Homo sapiens (human) | 0.5012 | |
| 5-hydroxytryptamine receptor 1D | Sus scrofa (pig) | 0.02 | |
| 5-hydroxytryptamine receptor 1A | Mus musculus (house mouse) | 0.45 | |
| 5-hydroxytryptamine receptor 3D | Homo sapiens (human) | 0.0073 | |
| 5-hydroxytryptamine receptor 3C | Homo sapiens (human) | 0.0073 | |
| Multidrug and toxin extrusion protein 1 | Homo sapiens (human) | 6.7 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bax, WA; De Vries, P; Heiligers, JP; Maassen vandenBrink, A; Saxena, PR; Wang, W; Yocca, FD | 1 |
| Bax, WA; Ferrari, MD; MaassenVanDenBrink, A; Reekers, M; Saxena, PR | 1 |
| Dahlöf, CG; Falk, L; Lewis, CP; Risenfors, M | 1 |
| Cutler, NR; Ford, NF; Fulmor, IE; Jhee, SS; Salazar, DE; Sramek, JJ | 1 |
| Edvinsson, L; Goadsby, PJ; Knight, YE | 1 |
2 trial(s) available for avitriptan and sumatriptan
| Article | Year |
|---|---|
Safety trial with the 5HT1B/1D agonist avitriptan (BMS-180048) in patients with migraine who have experienced pressure, tightness, and/or pain in the chest, neck, and/or throat following sumatriptan.
Topics: Adult; Chest Pain; Diagnosis, Differential; Electrocardiography; Electrocardiography, Ambulatory; Female; Humans; Indoles; Male; Middle Aged; Migraine Disorders; Myocardial Ischemia; Neck Pain; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Safety; Serotonin Receptor Agonists; Sulfonamides; Sumatriptan; Tryptamines; Ultrasonography | 1998 |
A double-blind, randomized, crossover assessment of blood pressure following administration of avitriptan, sumatriptan, or placebo to patients with mild to moderate hypertension.
Topics: Adult; Aged; Blood Pressure; Double-Blind Method; Female; Humans; Hypertension; Indoles; Male; Middle Aged; Sulfonamides; Sumatriptan; Tryptamines | 1999 |
3 other study(ies) available for avitriptan and sumatriptan
| Article | Year |
|---|---|
Effects of avitriptan, a new 5-HT 1B/1D receptor agonist, in experimental models predictive of antimigraine activity and coronary side-effect potential.
Topics: Animals; Arteriovenous Anastomosis; Blood Pressure; Carotid Arteries; Coronary Vessels; Head; Heart Rate; Hemodynamics; Humans; Indoles; Migraine Disorders; Muscle Contraction; Muscle, Smooth, Vascular; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Serotonin Receptor Agonists; Sulfonamides; Sumatriptan; Swine; Tryptamines; Vasoconstrictor Agents | 1997 |
Coronary side-effect potential of current and prospective antimigraine drugs.
Topics: Adolescent; Adult; Aged; Angina Pectoris; Child; Coronary Vessels; Dihydroergotamine; Ergotamine; Female; Humans; In Vitro Techniques; Indoles; Male; Methysergide; Middle Aged; Migraine Disorders; Piperidines; Sulfonamides; Sumatriptan; Triazoles; Tryptamines; Vasoconstrictor Agents | 1998 |
Blockade of calcitonin gene-related peptide release after superior sagittal sinus stimulation in cat: a comparison of avitriptan and CP122,288.
Topics: Animals; Calcitonin Gene-Related Peptide; Cats; Cerebral Arteries; Cerebrovascular Circulation; Cranial Sinuses; Electric Stimulation; Indoles; Jugular Veins; Migraine Disorders; Pyrrolidines; Serotonin Receptor Agonists; Sulfonamides; Sumatriptan; Trigeminal Nerve; Tryptamines | 1999 |