avermectin has been researched along with dextrothyroxine in 548 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 55 (10.04) | 18.7374 |
1990's | 104 (18.98) | 18.2507 |
2000's | 125 (22.81) | 29.6817 |
2010's | 222 (40.51) | 24.3611 |
2020's | 42 (7.66) | 2.80 |
Authors | Studies |
---|---|
Fritz, LC; Gorio, A; Wang, CC | 1 |
Baker, EE; Birnbaum, J; Burg, RW; Currie, SA; Hartman, R; Kong, YL; Miller, BM; Monaghan, RL; Oiwa, R; Olson, G; Omura, S; Putter, I; Stapley, EO; Tunac, JB; Wallick, H | 1 |
Williams, M; Yarbrough, GG | 1 |
Blair, LS; Campbell, WC | 1 |
Benz, GW; Ernst, JV | 1 |
Arena, JP; Cully, DF; Liu, KK; Paress, PS; Schaeffer, JM | 2 |
Hayes, EC; Meinke, PT; Mrozik, H; Rohrer, SP; Schaeffer, JM | 1 |
Colquhoun, L; Holden-Dye, L; Walker, RJ | 1 |
Chartrain, M; Gbewonyo, K; Goegelman, R; Greasham, R; White, R | 1 |
Mrozik, H; Pivnichny, JV; Stong, JD; Waksmunski, FS | 1 |
Blizzard, TA; Fisher, MH; Frankshun, RA; Margiatto, GM; Mrozik, H; Shoop, WL | 1 |
Fisher, MH; Hayes, EC; Meinke, PT; Mrozik, H; Rohrer, SP; Schaeffer, JM | 1 |
Shoop, WL | 1 |
Jurková, M; Míková, H; Rezanka, T | 1 |
Dezeny, G; Gewain, KM; Gibbons, PH; MacNeil, DJ; MacNeil, T; Ruby, CL | 1 |
Fisher, MH; Mrozik, H | 1 |
Orton, CJ; Rugg, D; Watts, JE | 1 |
Hájek, P; Novák, J; Rezanka, T; Vanĕk, Z | 1 |
Danis, SJ; Gewain, KM; Gibbons, PH; MacNeil, DJ; MacNeil, T; Occi, JL; Ruby, CL | 1 |
Payne, GT; Soderlund, DM | 1 |
Evans, NA; Gration, KA; Harrow, ID | 1 |
Arena, JP; Cully, DF; Liu, KK; Paress, PS | 1 |
Haber, CL; Heckaman, CL; Li, GP; Thompson, DP; Whaley, HA; Wiley, VH | 1 |
Gill, JH; Lacey, E; Redwin, JM; van Wyk, JA | 2 |
Dybas, RA; Lasota, JA | 1 |
Beck, D; Hafner, EW; Holdom, KS; Holley, BW; Lee, SE; McArthur, HA; Wax, RG; Wernau, WC | 1 |
Bu'Lock, JD; Dutton, CJ; Gibson, SP; Goudie, AC; Holdom, KS; Pacey, MS; Richards, MK; Ruddock, JC | 1 |
Ikeda, H; Omura, S; Tanaka, H | 1 |
Holden-Dye, L; Walker, RJ | 1 |
Acton, SL; Arison, BH; Schulman, MD; Valentino, DL | 1 |
Malaník, V; Malaníková, M; Marek, M | 1 |
Chalmers, AE; Miller, TA; Olsen, RW | 1 |
Wright, DJ | 1 |
Robertson, B | 1 |
Curdová, E; Jechová, V; Vanĕk, Z; Zima, J | 1 |
Chen, TS; Inamine, ES | 1 |
Mrozik, H; Schaeffer, JM; Stiffey, JH | 1 |
Blizzard, TA; Fisher, MH; Mrozik, H; Preiser, FA; Ruby, CL | 1 |
Bokisch, AJ; Walker, RJ | 1 |
Donahue, MJ; Martin, RE | 1 |
Eskola, P; Fisher, MH; Linn, BO; Lusi, A; Matzuk, A; Mrozik, H; Ostlind, DA; Preiser, FA; Schaeffer, JM | 1 |
Chen, TS; Hensens, OD; Inamine, ES; Ostlind, DA; Zink, D | 1 |
Brezner, J; Gordnier, PM; Tanenbaum, SW | 1 |
Goldberg, RB; Greene, J | 1 |
Fukuda, H; Matsumoto, K; Yamazaki, J | 1 |
Hensens, O; Schulman, MD; Valentino, D | 1 |
Ammendola, D; De Sarro, A; De Sarro, GB; Germanà, G; Naccari, F; Rotiroti, D | 1 |
Chang, V | 1 |
Ikeda, H; Kotaki, H; Omura, S; Tanaka, H | 1 |
Besier, RB; Casey, R; De Chaneet, GC; Dixon, FF; Mitchell, RK | 1 |
Barton, R; Button, C; Honey, P; Rickford, P | 1 |
Carrigan, MJ; Eagleson, JS; Seaman, JT; Webb, RF | 1 |
Campbell, WC | 3 |
Davies, HG; Green, RH | 1 |
Ruby, C; Schulman, MD; Streicher, S; Valentino, D | 1 |
Ikeda, H; Kotaki, H; Omura, S | 1 |
Kaplan, L; Nallin, M; Schulman, MD; Valentino, D | 1 |
Marriner, S | 1 |
Hensens, OD; Kaplan, L; Nallin, M; Ostlind, DA; Schulman, MD; Valentino, D; Zink, D | 1 |
Miller, TW; Onishi, JC | 1 |
Drexler, G; Sieghart, W | 2 |
Calcott, PH; Fatig, RO | 2 |
Kass, IS; Stretton, AO; Wang, CC | 1 |
Risley, EA; Williams, M | 1 |
Birtle, AJ; Roberts, IT; Wright, DJ | 1 |
Goodwin, LG | 1 |
Parrish, MD; Roberts, RB | 1 |
Pivnichny, JV; Shim, JS; Zimmerman, LA | 1 |
Hotson, IK | 1 |
Campbell, WC; Chabala, JC; Egerton, JR; Eskola, P; Fisher, MH; Lusi, A; Mrozik, H; Ostlind, DA; Peterson, LH; Tolman, RL; Woods, MF | 1 |
Bowen, JM | 1 |
Cifelli, S; Egerton, JR; Eskola, P; Fisher, MH; Mrozik, H; Ostlind, DA | 1 |
Denham, DA | 1 |
Conroy, JA; Ho, P; Malatesta, PF; O'Shanny, WJ; Wilkins, CA | 1 |
Drummond, RO; Miller, JA; Whetstone, TM | 1 |
Cifelli, S; Ostlind, DA | 1 |
James, PS; Picton, J; Riek, RF | 1 |
Eskola, P; Fink, DW; Mrozik, H; Tolan, JW; Zimmerman, LA | 1 |
Fisher, MH; Mrozik, H; Shoop, WL | 1 |
Endo, H; Ikeda, H; Ohta, T; Omura, S; Pang, CH; Tanaka, H | 1 |
Ikeda, H; Omura, S | 1 |
Gill, JH; Lacey, E; Le Jambre, LF; Lenane, IJ | 1 |
Arena, JP; Cully, DF; Frazier, EG; Liu, KK; Mrozik, H; Paress, PS; Schaeffer, JM | 1 |
Denoya, CD; Fedechko, RW; Hafner, EW; McArthur, HA; Morgenstern, MR; Skinner, DD; Stutzman-Engwall, K; Wax, RG; Wernau, WC | 1 |
Bloomquist, JR; Campos, F; Clark, JM; Scott, JG | 1 |
Khalkova, Zh | 1 |
Ikeda, H; Matsuzaki, K; Omura, S; Pang, CH; Tanaka, H | 2 |
Ikeda, H; Matsuzaki, K; Omura, S; Pang, CH; Takada, Y; Tanaka, H | 1 |
Arena, JP; Cully, DF; Liu, KK; Paress, PS; Schaeffer, JM; Van der Ploeg, LH; Vassilatis, DK | 1 |
Gewain, KM; MacNeil, DJ; MacNeil, T; Occi, JL | 1 |
Boersema, JH; Kooyman, FN; Kwa, MS; Roos, MH; Veenstra, JG | 1 |
Dyson, P; Evans, M; Kaczmarek, FS; Stutzman-Engwall, K | 1 |
Birzin, ET; Hayes, EC; Jacobson, EB; Rohrer, SP; Schaeffer, JM | 1 |
Bormann, J; Schönrock, B | 1 |
Ide, J; Muramatsu, S; Naito, S; Nakada, Y; Nanba, T; Owatari, Y | 1 |
Arison, B; Doherty, P; Schulman, M; Zink, D | 1 |
Arison, B; Doherty, P; Schulman, M | 1 |
Ridsdill-Smith, TJ | 1 |
King, KL | 1 |
McCracken, DI | 1 |
Mahon, RJ; Waller, PJ; Wardhaugh, KG | 1 |
Strong, L | 1 |
Herd, R; Strong, L; Wardhaugh, K | 1 |
Sams, R | 1 |
Ikeda, H; Omura, S; Pang, CH; Takada, Y; Tanaka, H | 1 |
Kofronová, O; Kopecký, J; Novák, J; Vanĕk, Z | 1 |
Gewain, KM; MacNeil, DJ; MacNeil, T | 1 |
Danilenko, VN; Mironov, VA; Sergeev, AV; Voronkova, VV | 1 |
Gil, A; Hansen, JW; Nari, A; Salles, J; Waller, PJ | 1 |
MacNeil, DJ | 1 |
Baumgartner, W; Kutzer, E; Loupal, G; Löwenstein, M | 1 |
Claerebout, E; Vercruysse, J | 1 |
Danilenko, VN; Mironov, VA; Sergeeva, AV | 1 |
Gill, JH; Redwin, JM | 1 |
Herd, R | 1 |
Dong, Z; Patel, Y; Saikumar, P; Venkatachalam, MA; Weinberg, JM | 1 |
Purnell, RE; Titchener, RN | 1 |
Benchaoui, HA; McKellar, QA | 1 |
DeMontigny, P; Egerton, JR; Fink, DW; Fisher, MH; Mrozik, H; Shoop, WL; Skelly, BJ; Turner, MJ; Williams, JB | 1 |
Barth, D; Campbell, WC; Costa, S; Eary, CH; Egerton, JR; Eskola, P; Fisher, MH; Fulton, RK; Gregory, LM; Haines, HW; Michael, BF; Mrozik, H; Ostlind, DA; Seward, RL; Shoop, WL; Skelly, BJ; Slayton, L; Turner, MJ | 1 |
Krieger, RI; Rosenheck, LA; Schuester, LL | 1 |
Arena, JP; Cully, DF; Elliston, KO; Hamelin, M; Paress, PS; Schaeffer, JM; Van der Ploeg, LH; Vassilatis, DK | 1 |
Gray, AK | 1 |
Scarff, DH | 1 |
Kempner, E; Pomes, A; Rohrer, S | 1 |
Laughton, DL; Lunt, GG; Wolstenholme, AJ | 1 |
Doody, GM | 1 |
Danilenko, VN; Mironov, VA; Sergeeva, AV; Voronkova, VV | 1 |
Barnes, TM; Hekimi, S | 1 |
Arena, JP; Cully, DF; Plasterk, RH; Schaeffer, JM; Van der Ploeg, LH; Vassilatis, DK; Wilkinson, HA | 1 |
Cortés, J; Dunster, NJ; Leadlay, PF; Marsden, AF; Staunton, J; Wilkinson, B | 1 |
Ikeda, H; Inokoshi, J; Ohta, T; Omura, S; Wang, LR | 1 |
Gill, JH; Kerr, CA; Lacey, E; Shoop, WL | 1 |
Detry, J; Farnir, F; Lonneux, JF; Losson, BJ; Nguyen, TQ | 1 |
Gill, JH; Lacey, E | 1 |
Delany, NS; Laughton, DL; Wolstenholme, AJ | 1 |
Cochrane, BJ; Richmond, RC; Windelspecht, M | 1 |
Blizzard, TA; Dawson, GR; Fisher, MH; Meinke, PT; Michael, BF; Mrozik, H; Shoop, WL | 1 |
Bannan, SC; Geary, TG; Klein, RD; Nulf, SC; Sangster, NC; Weiss, AS | 1 |
Gonzales, SA; Hurlbut, JA; Pfenning, AP; Roybal, JE; Rupp, HS; Turnipseed, SB | 1 |
Gill, J; Sangster, NC | 1 |
Gopal, RM; Pomroy, WE; West, DM | 1 |
Driniaev, VA; Korystov, IuN; Krugliak, EB; Kublik, LN; Levitman, MKh; Mosin, VA; Shaposhnikova, VV; Sterlina, TS; Viktorov, AV | 1 |
Roudaut, B | 1 |
Ikeda, H; Nonomiya, T; Ohta, T; Omura, S; Usami, M | 1 |
Geary, TG; Sangster, NC; Thompson, DP | 1 |
Sangster, NC | 1 |
Baru, RV; Chukina, SI; Driniaev, VA; Krugliak, EB; Mosin, VA; Novik, TS; Piatova, VA; Riabova, VA | 1 |
Davies, RA; Denoya, CD; Fedechko, RW; Hutchinson, CR; Lobo, S; McArthur, HAI; Morgenstern, MR; Reynolds, KA; Skinner, DD; Zhang, YX | 1 |
Huisman, MT; Schinkel, AH; Smit, JW; van Tellingen, O; Wiltshire, HR | 1 |
Baker, P; Gill, JH; Le Jambre, LF; Lenane, IJ | 1 |
Drinyaev, VA; Grichenko, AS; Kokoz, YM; Korystova, AF; Kruglyak, EB; Mosin, VA; Sterlina, TS; Tsyganova, VG; Victorov, AV; Zenchenko, KI | 1 |
Cabri, W; Gianelli, L; Mellerio, GG; Rossi, A; Siviero, E; Sogli, L | 1 |
Ehrhart, JC; Evans, EI; Godin, CS; Jernigan, AD; Krautmann, MJ; McCall, JW; Novotny, MJ; Rowan, TG; Sun, F | 1 |
De Keulenaer, K; Evans, EI; Godin, CS; Jernigan, AD; Krautmann, MJ; McCall, JW; Novotny, MJ; Rowan, TG; Wang, C | 1 |
Casida, JE; Cole, LM; Tsukamoto, Y | 1 |
Banks, BJ; Bishop, BF; Evans, NA; Gibson, SP; Goudie, AC; Gration, KA; Pacey, MS; Perry, DA; Witty, MJ | 1 |
Danaher, M; Glennon, JD; O'Keeffe, M | 2 |
Bayley, PJ; Dawson, GR; Marshall, GR; McKernan, RM; Meinke, PT; Schaeffer, JM; Smith, A; Wafford, KA | 1 |
Chartier, C; Etter, E; Goudeau, C; Hoste, H; Lefrileux, Y; Soubirac, F | 1 |
Bornstein, S; Jacobson, M; Palmér, E; Wallgren, P | 1 |
Driniaev, VA; Korystov, IuN; Krugliak, EB; Kublik, LN; Levitman, MKh; Mosin, VA; Narimanov, AA; Shaposhnikova, VV; Sterlina, TS; Viktorov, AV | 1 |
Howells, L; Sauer, MJ | 1 |
Craig, TM; Jensen, JM; Young, KE | 1 |
Hu, F; Shao, Y; Shi, Z | 1 |
Barnes, EH; Dobson, RJ; Le Jambre, LF; Lenane, IJ; Stein, PA | 1 |
Ikeda, H | 1 |
Li, J; Luo, H; Wu, Z; Xu, X; Zhu, L | 1 |
Danaher, M; Glennon, JD; Howells, L; O'Keeffe, M | 1 |
Köhler, P | 1 |
Mañes, J; Popa, DS; Redondo, MJ; Valenzuela, AI | 1 |
Berestovsky, GN; Drinyaev, VA; Kataev, AA; Kokoz, YM; Kruglyak, EB; Mosin, VA; Sterlina, TS | 1 |
Fonstein, L; Gewain, KM; Hutchinson, CR; Kulowski, K; Lomovskaya, N; MacNeil, DJ; Occi, JL; Wohlert, S | 1 |
Bhagwan, PS; Khan, FA; Sanyal, PK; Singh, D; Swarnkar, CP | 1 |
Gregory, LM; Meinke, PT; Shoop, WL; Zakson-Aiken, M | 1 |
Anziani, OS; Guglielmone, AA; Suarez, V; Vazquez, R; Zimmermann, G | 1 |
Furlong, J; Martins, JR | 1 |
Driniaev, VA; Grichenko, AS; Kokoz, IuM; Korystova, AF; Krugliak, EB; Mosin, VA; Sterlina, TS; Tsyganova, VG; Viktorov, AV; Zenchenko, KI | 1 |
Berestovskiĭ, GN; Driniaev, VA; Kataev, AA; Kataev, TS; Kokoz, IuM; Krugliak, EB; Mosin, VA; Sterlina, TS; Viktorov, AV | 1 |
Ikeda, H; Nonomiya, T; Omura, S | 1 |
Huang, SJ; Sha, CK; Zhan, ZP | 1 |
Hertweck, C; Moore, BS | 1 |
Driniaev, VA; Kostenko, MA; Miakisheva, SN; Mosin, VA | 1 |
Veale, PI | 1 |
Dede, S; Deger, S; Deger, Y | 1 |
Maciel, AE; Rehbein, S; Visser, M; Winter, R | 1 |
Goodfellow, M; Kim, SB | 1 |
Iwai, Y; Matsumoto, A; Omura, S; Seino, A; Takahashi, Y; Ueno, J | 1 |
Argentine, JA; Halliday, WR; Jansson, RK; Starner, VR | 1 |
Chen, Z; Li, J; Song, Y; Wen, Y | 1 |
Biró, S; Choi, CY; Hwang, YS; Kim, ES | 1 |
Ceresér, VH; Corrêa, BL; Evans, DE; Martins, JR | 1 |
Chen, Y; Conlon, S; Fedechko, R; Gustafsson, C; Kaczmarek, F; Krebber, A; McArthur, H; Minshull, J; Raillard, SA; Stutzman-Engwall, K | 1 |
Driniaev, VA; Pleshkov, EN; Viktorov, AV | 1 |
Deng, Z; Sun, Y; Tu, G; Zhou, X | 1 |
Ikeda, H; Ishikawa, J; Jackson, C; Kelly, SL; Lamb, DC; Nelson, DR; Omura, S; Skaug, T; Waterman, MR | 1 |
Gaisser, S; Galloway, IS; Kaja, AL; Kellenberger, L; Kendrew, SG; Leadlay, PF; Lill, RE; Low, L; McArthur, HA; Sheridan, RM; Staunton, J; Stutzman-Engwall, K; Weston, AJ; Wilkinson, B; Wirtz, G | 1 |
Portillo, V; Wolstenholme, AJ; Yates, DM | 1 |
Beech, RN; Blackhall, WJ; Prichard, RK | 1 |
Harder, A; Nagai, K; Omura, S; Shiomi, K; Sunazuka, T; Turberg, A | 2 |
Choi, CY; Hwang, YS; Kim, ES; Yoon, YJ | 1 |
Braun, U; Gansohr, B; Schweizer, G; Strabel, D | 1 |
Bai, H; Chen, J; Chu, J; Luo, J; Zhang, S; Zhuang, Y | 1 |
Beech, RN; Dent, JA; Liu, J; Prichard, RK | 1 |
Drinyaev, VA; Ermakova, NV; Korystov, YN; Kruglyak, EB; Kublik, LN; Levitman, MKh; Mosin, VA; Novik, TS; Shaposhnikova, VV; Sterlina, TS | 2 |
Chiao, J; Gong, W; Jiang, W; Yang, Y | 1 |
Driniaev, VA; Ermakova, NV; Korystov, IuN; Krugliak, EB; Kublik, LN; Levitman, MKh; Mosin, VA; Novik, TS; Shaposhnikova, VV; Sterlina, TS | 1 |
Guo, SJ; Lin, WC; Liu, SS; Shi, ZH | 1 |
Driniaev, VA; Ermakova, NV; Korystov, IuN; Krugliak, EB; Kublik, LN; Levitman, MKh; Mosin, VA; Novik, TC; Shaposhnikova, VV; Sterlina, TC | 1 |
Duan, YH; Guo, YP; Li, CL; Lu, FP; Ma, EB | 1 |
Bronshteĭn, AM; Kedrov, AV; Malyshev, NA; Ramirez, LA | 1 |
Chen, JF; Li, ZZ; Liu, AQ; Wen, LX; Zou, HK | 1 |
Liang, YX; Zheng, YH; Zhou, JC; Zhu, HJ | 1 |
Dvojnos, GM; Kharchenko, VA; Kuzmina, TA; Starovir, AI | 1 |
Byeon, WH; Yong, JH | 1 |
Bowen, JM; Vitayavirasak, B | 1 |
Erzen, NK; Flajs, VC; Kolar, L; Kuzner, J; Marc, I; Pogacnik, M | 1 |
Buckel, D; Buckel, TG; Hammer, PE; Hill, DS; Jungmann, V; Ligon, JM; Molnár, I; Pachlatko, JP; Zirkle, R | 1 |
Buckel, TG; Gross, F; Hammer, PE; Hill, DS; Jungmann, V; Ligon, JM; Molnár, I; Pachlatko, JP; Zirkle, R | 1 |
Chen, JF; Li, ZZ; Liu, AQ; Liu, F; Sun, HY; Wang, Q; Wen, LX; Xu, SA; Yu, W | 1 |
Walsh, CT | 1 |
Andersen, WC; Karbiwnyk, CM; Miller, KE; Roybal, JE; Turnipseed, SB | 1 |
Abend, A; Beasley, CA; Fliszar, K; Hwang, TL; McCollum, DG; Reed, RA | 1 |
Rogers, AT; Wolstenholme, AJ | 1 |
Chen, Z; Li, J; Li, M; Song, Y; Wen, Y; Zhang, X | 2 |
Alison, MW; Foil, LD; Guerrero, FD; Kim, JH; Kimball, MM; Oremus, G | 1 |
Wei, X; Yinghua, Z; Yunxiang, L | 1 |
Kwon, HJ; Rajkarnikar, A; Ryu, YW; Suh, JW | 2 |
He, J; Hou, X; Jiang, H; Shen, J; Shi, W; Yang, J | 1 |
Learmount, J; Morgan, C; Smith, G; Taylor, MA | 1 |
Cerkvenik-Flajs, V; Crooks, SR; Danaher, M; Howells, LC; O'Keeffe, M | 1 |
Artho, R; Hertzberg, H; Kohler, L; Schnyder, M; Torgerson, PR | 1 |
Chen, JF; Li, ZZ; Liu, AQ; Liu, F; Sun, HY; Wang, Q; Wen, LX | 1 |
Albermann, C; Fu, X; Thorson, JS; Zhang, C | 1 |
Crouse, GD; Gifford, J; Graupner, PR; Kaja, AL; Karr, L; Leadlay, PF; Lewer, P; Lill, RE; Martin, CJ; Sheehan, LS; Sheridan, RM; Sparks, TC; Vousden, WA; Waldron, C; Wilkinson, B | 1 |
Burka, JF; Kibenge, FS; Tribble, ND | 1 |
Gledhill, A; Macdonald, N | 1 |
Berendsen, BJ; Mulder, PP; van Rhijn, HJ | 1 |
Beaumont, DJ; McCracken, DI; Nager, RG; Webb, L | 2 |
Deng, ZX; Tao, MF; Tao, WX; Wu, J | 1 |
Chen, JF; Li, Y; Li, ZZ; Wen, LX | 1 |
Botejue, A; Buckel, D; Frey, G; Hill, DS; Jörg, M; Jungmann, V; Ligon, JM; Mason, D; Molnár, I; Moore, D; Pachlatko, JP; Richardson, TH; Spangenberg, P; Stege, JT; Trefzer, A; Wall, MA; Zirkle, R | 1 |
Bueno, MJ; Fernández-Alba, AR; Garcia-Reyes, JF; Hernando, MD; Suárez-Barcena, JM | 1 |
Lin, YW; Miyata, T; Wu, G | 1 |
Prell, A; Rezanka, T; Sigler, K; Sobotka, M | 1 |
Brayden, DJ; Griffin, J | 1 |
Crnjar, R; Liscia, A; Masala, C; Solari, P; Sollai, G | 1 |
Liu, YH; Wang, J; Wang, XJ | 1 |
Im, JH; Kim, ES; Kim, MG | 1 |
Ayers, S; Brown, CM; Genilloud, O; Grund, A; Powell, JS; Salazar, O; Singh, SB; Thompson, D; Zink, DL | 1 |
Houk, KN; Kessabi, FM; Luft, JA; Winkler, T | 2 |
Dong, JY; Li, JH; Shen, KZ; Song, HC; Sun, R; Tang, YS; Wang, CR; Wang, L; Wang, LM; Zhang, KQ; Zhou, YP | 1 |
Chen, J; Chen, L; Jiang, W; Lu, Y; Qin, Z; Shu, D; Yang, S; Zhang, W | 1 |
Chen, Z; Li, J; Li, M; Lin, X; Song, Y; Wen, Y; Zhang, X | 1 |
Björklund, E; Fink, G; Halling-Sørensen, B; Krogh, KA; Loeffler, D; Ternes, TA | 1 |
Thorson, JS; Williams, GJ | 1 |
Forrest, F; Keenliside, J; Kendall, J; Noot, DK; Thompson, TS; van den Heever, JP | 1 |
dos Santos, AR; Falcão, CA; Férézou, JP; Kaiser, CR; Muzitano, MF; Rossi-Bergmann, B | 1 |
Ikeda, H; Kitani, S; Nihira, T; Noguchi, S; Sakamoto, T | 1 |
Tao, M; Zhu, J | 1 |
Liu, S; Liu, Z; Wang, H; Wang, Z | 1 |
Cassayre, J; Hüter, OF; Jung, PM; Kessabi, FM; Maienfisch, P; Pitterna, T; Quaranta, L; Tobler, H | 1 |
Choi, SS; Duong, CT; Kim, ES; Lee, HN; Lee, SY | 1 |
Boina, DR; Onagbola, EO; Salyani, M; Stelinski, LL | 1 |
Chen, N; Ci, X; Deng, X; Li, H; Song, Y; Yu, L; Yu, Q; Zhang, X | 1 |
Dongbo, S; Donghua, G; Shiwen, X; Shu, L | 1 |
Huang, Z; Lin, Y; Lu, S; Yang, F; Yang, S; Zhang, Y; Zheng, D | 1 |
Fan, CK; Huang, CT; Lin, CH; Lin, SP; Sung, YF | 1 |
Hino, T; Inoue, K; Oka, H; Yoshimi, Y | 1 |
Chen, X; Gao, H; Gou, Z; Liu, J; Liu, M; Liu, X; Luo, A; Xu, B; Zhang, L; Zhang, W; Zheng, C; Zhou, X; Zhuo, Y | 1 |
Chen, Z; Guo, J; Li, J; Li, L; Wen, Y; Zhao, J | 1 |
Brimble, MA; Liu, YC; Sperry, J | 1 |
Chen, Z; Song, Y; Wang, S; Wang, Y; Wen, Y; Zhao, X | 1 |
Ji, P; Liang, Y; Zhu, HB | 1 |
Gao, X; Hu, J; Liang, P; Shi, X | 1 |
Chen, Z; Guo, J; Li, J; Li, L; Song, Y; Wen, Y | 1 |
Guo, JB; Li, ZX; Liu, C; Ma, JK; Wu, G; Yang, JL | 1 |
Larramendy, ML; Molinari, G; Soloneski, S | 1 |
Tang, YY; Yang, YN; Zhu, BQ | 1 |
Alves, SN; Melo, AL; Serrão, JE | 1 |
Chen, D; Gao, H; Gou, Z; Liu, J; Liu, M; Shang, P; Zhang, L; Zhang, W; Zhou, X; Zhuo, Y | 1 |
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Dong, J; Dong, Z; He, N; Liu, F; Ma, F; Pan, E; Wang, G; Wang, Y; Zhang, T | 1 |
Dong, J; Dong, Z; He, N; Liu, F; Ma, F; Pan, E; Wang, Y; Wu, X; Zhang, T | 1 |
Cernava, T; Deng, Y; Gong, P; Jin, D; Li, Q; Li, X; Wang, C; Zhang, Y; Zhu, X | 1 |
Bamao, Z; Gou, Z; He, F; Li, J; Li, Z; Xu, T | 1 |
Chen, H; Chen, Z; Hao, L; Zhao, M; Zhou, H; Zhou, X | 1 |
Du, W; Liu, C; Wang, L; Wang, M; Wang, X | 1 |
Ando, M; Horii, S; Matsumoto, A; Nakashima, T; Samuel, AZ; Takahashi, Y; Take, A; Takeyama, H | 1 |
Cid, LP; Cornejo, I; Cuevas, P; Sepúlveda, FV; Tribiños, F | 1 |
54 review(s) available for avermectin and dextrothyroxine
Article | Year |
---|---|
The chemistry and pharmacology of avermectins.
Topics: Animals; Anthelmintics; Antiprotozoal Agents; Humans; Ivermectin | 1992 |
Neurobiology of arthropod parasites.
Topics: Acetylcholine; Animals; Arthropod Vectors; Dopamine; gamma-Aminobutyric Acid; Insecticides; Ivermectin; Neurotransmitter Agents; Octopamine; Organophosphorus Compounds; Synaptic Transmission; Ticks | 1991 |
Avermectins, a novel class of compounds: implications for use in arthropod pest control.
Topics: Animals; Arthropods; Humans; Ivermectin; Pest Control | 1991 |
Actions of avermectins on cultured neurons.
Topics: Animals; Cells, Cultured; Insecta; Ivermectin; Mammals; Neurons | 1988 |
The chemotherapy of parasitic infections.
Topics: Amebiasis; Animals; Anthelmintics; Cattle; Cestode Infections; Cryptosporidiosis; Fascioliasis; Humans; Insect Control; Intestinal Diseases, Parasitic; Ivermectin; Lactones; Leishmaniasis; Malaria; Mebendazole; Nematode Infections; Niclosamide; Parasitic Diseases; Praziquantel; Trematode Infections; Trypanosomiasis | 1986 |
Avermectins and milbemycins.
Topics: Alkylation; Anti-Bacterial Agents; Antifungal Agents; Antiprotozoal Agents; Chemical Phenomena; Chemistry; Fermentation; Ivermectin; Lactones; Macrolides; Oxidation-Reduction; Structure-Activity Relationship | 1986 |
Recent advances in research on filariasis. Chemotherapy.
Topics: Animals; Anti-Inflammatory Agents; Arsenicals; Benzimidazoles; Diethylcarbamazine; Drug Evaluation, Preclinical; Filariasis; Filaricides; Filarioidea; Humans; Ivermectin; Lactones; Onchocerciasis; Suramin | 1984 |
The avermectins: A new family of antiparasitic agents.
Topics: Animals; Anoplura; Anthelmintics; Antinematodal Agents; Cattle; Cattle Diseases; Dog Diseases; Dogs; Horse Diseases; Horses; Ivermectin; Lactones; Mite Infestations; Nematode Infections; Sheep; Sheep Diseases; Swine; Swine Diseases; Tick Infestations | 1982 |
An introduction to the avermectins.
Topics: Animals; Anthelmintics; Antiprotozoal Agents; Cattle; Cattle Diseases; Chemical Phenomena; Chemistry; Dog Diseases; Dogs; Ectoparasitic Infestations; Ivermectin; Lactones; Nematoda; Nematode Infections; Rabbits; Sheep; Sheep Diseases; Species Specificity; Streptomyces | 1981 |
Structure and activity of avermectins and milbemycins in animal health.
Topics: Animals; Anthelmintics; Anti-Bacterial Agents; Antiprotozoal Agents; Dog Diseases; Dogs; Helminthiasis; Helminthiasis, Animal; Ivermectin; Macrolides; Molecular Structure; Parasitic Diseases; Parasitic Diseases, Animal; Sheep; Sheep Diseases; Structure-Activity Relationship | 1995 |
Control of avermectin biosynthesis in Streptomyces avermitilis for the selective production of a useful component.
Topics: Animals; Anthelmintics; Antiprotozoal Agents; Humans; Ivermectin; Mutation; Streptomyces | 1995 |
Resistance to avermectins: extent, mechanisms, and management implications.
Topics: Animals; Coleoptera; Houseflies; Insect Control; Insecticide Resistance; Insecticides; Ivermectin; Mites | 1995 |
Molecular aspects of drug resistance in parasitic helminths.
Topics: Animals; Anthelmintics; Benzimidazoles; Caenorhabditis elegans; Drug Resistance; Helminthiasis; Helminthiasis, Animal; Helminths; Humans; Imidazoles; Ivermectin; Mutation; Thiazoles; Tubulin | 1993 |
The potential for avermectins to affect the nutrient economy of grazed pastures.
Topics: Animals; Anthelmintics; Arthropods; Australia; Coleoptera; Ecology; Feces; Invertebrates; Ivermectin; Minerals; Nematoda; Oligochaeta; Sheep; Soil Pollutants | 1993 |
The potential for avermectins to affect wildlife.
Topics: Animal Feed; Animals; Animals, Wild; Anthelmintics; Birds; Ecology; Feces; Insecta; Invertebrates; Ivermectin; Mammals; Poisoning | 1993 |
Regional and temporal use of avermectins for ruminants in Australia.
Topics: Animals; Anthelmintics; Australia; Cattle; Cattle Diseases; Climate; Ivermectin; Parasitic Diseases; Parasitic Diseases, Animal; Sheep; Sheep Diseases | 1993 |
Overview: the impact of avermectins on pastureland ecology.
Topics: Animals; Animals, Domestic; Anthelmintics; Antiprotozoal Agents; Biodegradation, Environmental; Coleoptera; Diptera; Ecology; Environmental Pollution; Feces; Insecta; Ivermectin; Parasitic Diseases; Parasitic Diseases, Animal | 1993 |
Chemical assay of avermectins by high performance liquid chromatography with fluorescence detection.
Topics: Animals; Chromatography, High Pressure Liquid; Ivermectin; Spectrometry, Fluorescence; Terminology as Topic | 1993 |
Avermectins.
Topics: Animals; Antiparasitic Agents; Cloning, Molecular; Genes, Bacterial; Genome, Bacterial; Humans; Ivermectin; Molecular Structure; Multienzyme Complexes; Parasitic Diseases; Streptomyces | 1995 |
Effect of chemoprophylaxis on immunity to gastrointestinal nematodes in cattle.
Topics: Animals; Anthelmintics; Cattle; Cattle Diseases; Immunity; Intestinal Diseases, Parasitic; Ivermectin; Nematode Infections | 1996 |
Avermectins and milbemycins.
Topics: Animals; Anthelmintics; Anti-Bacterial Agents; Antiprotozoal Agents; Cattle; Cattle Diseases; Delayed-Action Preparations; Ivermectin; Macrolides; Species Specificity; Structure-Activity Relationship | 1996 |
[Biosynthesis of avermectins: physiological and technological aspects].
Topics: Anti-Bacterial Agents; Bacteriological Techniques; Culture Media; Fermentation; Ivermectin; Streptomyces; Structure-Activity Relationship | 1997 |
Avermectin/milbemycin resistance in trichostrongyloid nematodes.
Topics: Animals; Anthelmintics; Anti-Bacterial Agents; Drug Resistance; Indolizines; Ivermectin; Larva; Macrolides; Sheep; Sheep Diseases; Spiro Compounds; Trichostrongyloidea; Trichostrongyloidiasis | 1998 |
Pharmacology of anthelmintic resistance.
Topics: Animals; Anthelmintics; Benzimidazoles; Cattle; Drug Resistance; Haemonchiasis; Haemonchus; Horses; Humans; Ivermectin; Levamisole; Sheep; Sheep Diseases; Swine; Trichostrongyloidiasis; Trichostrongylus | 1999 |
Frontiers in anthelmintic pharmacology.
Topics: Animals; Anthelmintics; Anti-Bacterial Agents; Anti-Infective Agents; ATP Binding Cassette Transporter, Subfamily B; Biological Availability; Caenorhabditis elegans; Cattle; Cattle Diseases; Depsipeptides; Diketopiperazines; Drug Resistance; Helminthiasis, Animal; Helminths; Ivermectin; Macrolides; Nitro Compounds; Peptides, Cyclic; Piperazines; Sheep; Sheep Diseases; Thiazoles | 1999 |
The biochemical basis of anthelmintic action and resistance.
Topics: Animals; Anthelmintics; Benzimidazoles; Drug Resistance; Helminthiasis; Helminths; Ivermectin; Nicotinic Agonists; Praziquantel | 2001 |
Biosynthesis and attachment of novel bacterial polyketide synthase starter units.
Topics: Amino Acids; Anti-Bacterial Agents; Bacteria; Bridged-Ring Compounds; Butyrates; Catalysis; Erythromycin; Ivermectin; Molecular Structure; Multienzyme Complexes; Peptides; Polyenes; Polyunsaturated Alkamides; Propionates; Rifabutin; Rifamycins; Salicylates | 2002 |
The avermectin receptors of Haemonchus contortus and Caenorhabditis elegans.
Topics: Animals; Anthelmintics; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Chloride Channels; Haemonchus; Humans; Ivermectin; Movement; Nematode Infections; Pharynx | 2003 |
Avermectin: biochemical and molecular basis of its biosynthesis and regulation.
Topics: Antiparasitic Agents; Gene Expression Regulation, Bacterial; Gene Order; Genes, Bacterial; Ivermectin; Multigene Family; Streptomyces | 2004 |
Natural insights for chemical biologists.
Topics: Bacterial Proteins; Biochemistry; Bleomycin; Computational Biology; Drug Design; Ivermectin; Lovastatin; Mass Spectrometry; Molecular Structure; Proteomics | 2005 |
Glutamate-gated chloride channels and the mode of action of the avermectin/milbemycin anthelmintics.
Topics: Animals; Anthelmintics; ATP Binding Cassette Transporter, Subfamily B; Chloride Channels; Ivermectin; Locomotion; Macrolides; Nematoda | 2005 |
Review of methodology for the determination of macrocyclic lactone residues in biological matrices.
Topics: Animals; Cattle; Chromatography, High Pressure Liquid; Chromatography, Liquid; Ivermectin; Macrolides; Mass Spectrometry; Molecular Structure; Spectrometry, Fluorescence | 2006 |
Potential impact of ABCB1 (p-glycoprotein) polymorphisms on avermectin toxicity in humans.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Brain; Haplotypes; Humans; Ivermectin; Pesticides; Polymorphism, Genetic | 2007 |
Natural product glycosyltransferases: properties and applications.
Topics: Aminocoumarins; Aminoglycosides; Anthracyclines; Directed Molecular Evolution; Drug Design; Enediynes; Enterobactin; Erythromycin; Glycosyltransferases; Ivermectin; Lactams; Macrolides; Models, Molecular; Oleandomycin; Protein Engineering; Teicoplanin; Vancomycin | 2009 |
New ventures in the chemistry of avermectins.
Topics: Crops, Agricultural; Disaccharides; Insecticides; Ivermectin; Structure-Activity Relationship | 2009 |
New ventures in the genotoxic and cytotoxic effects of macrocyclic lactones, abamectin and ivermectin.
Topics: Animals; Anthelmintics; Cell Line; DNA Damage; Humans; Ivermectin; Pesticides | 2010 |
Bovine hypodermosis--a global aspect.
Topics: Animals; Antibodies; Cattle; Cattle Diseases; Diptera; Ectoparasitic Infestations; Enzyme-Linked Immunosorbent Assay; Hemagglutination Tests; Immunoelectrophoresis; Insect Control; Insecticides; Ivermectin; Larva; Oviposition; Prevalence; Pupa; Species Specificity; Vaccination | 2010 |
Recent progress in understanding the interaction between avermectins and ligand-gated ion channels: putting the pests to sleep.
Topics: Amino Acid Sequence; Animals; Anthelmintics; Humans; Insecticides; Ivermectin; Ligand-Gated Ion Channels; Molecular Sequence Data; Protein Binding | 2010 |
History of avermectin and ivermectin, with notes on the history of other macrocyclic lactone antiparasitic agents.
Topics: Animals; Antiparasitic Agents; History, 20th Century; History, 21st Century; Humans; Ivermectin; Parasitic Diseases | 2012 |
Recent developments in the analysis of avermectin and milbemycin residues in food safety and the environment.
Topics: Animals; Antiparasitic Agents; Drug Residues; Environmental Pollutants; Food Analysis; Food Contamination; Ivermectin; Legislation, Food; Macrolides | 2012 |
Avermectin use in aquaculture.
Topics: Animals; Antiparasitic Agents; Aquaculture; Drug Residues; Drug Resistance; Fish Diseases; Ivermectin; Parasitic Diseases, Animal | 2012 |
Resistance to avermectin/milbemycin anthelmintics in equine cyathostomins - current situation.
Topics: Animals; Anthelmintics; Drug Resistance, Multiple; Horse Diseases; Horses; Ivermectin; Macrolides; Strongylida Infections; Strongyloidea | 2012 |
Toxicology of avermectins and milbemycins (macrocylic lactones) and the role of P-glycoprotein in dogs and cats.
Topics: Animals; Anthelmintics; ATP Binding Cassette Transporter, Subfamily B, Member 1; Breeding; Cat Diseases; Cats; Dog Diseases; Dogs; Ivermectin; Lactones; Macrolides; Neurotoxicity Syndromes | 2012 |
An overview on chemical derivatization and stability aspects of selected avermectin derivatives.
Topics: Animals; Anthelmintics; Drug Stability; Hydrogen-Ion Concentration; Ivermectin; Molecular Structure; Oxidation-Reduction | 2012 |
Synthetic biology of avermectin for production improvement and structure diversification.
Topics: Antiparasitic Agents; Humans; Ivermectin; Lactones; Streptomyces; Synthetic Biology | 2014 |
Recent advances in biochemistry and biotechnological synthesis of avermectins and their derivatives.
Topics: Biochemistry; Biotechnology; Ivermectin; Multigene Family; Mycobacterium tuberculosis; Streptomyces | 2014 |
[Avermectin, from winning the Nobel Prize to "innovation in China"].
Topics: China; Humans; Industrial Microbiology; Ivermectin; Nobel Prize; Pesticides; Streptomyces | 2016 |
Continuing fascination of exploration in natural substances from microorganisms.
Topics: Biological Products; Chemical Phenomena; Drug Discovery; Ivermectin; Microbiology | 2017 |
Learn from microbial intelligence for avermectins overproduction.
Topics: Bacteria; Biosynthetic Pathways; Fermentation; Genetic Engineering; Humans; Ivermectin | 2017 |
Recent progress in the isolation, bioactivity, biosynthesis, and total synthesis of natural spiroketals.
Topics: Animals; Biological Products; Chemistry Techniques, Synthetic; Furans; Humans; Ivermectin; Macrolides; Molecular Structure; Polyketides; Pyrans; Spiro Compounds; Structure-Activity Relationship; Terpenes | 2018 |
Preclinical evaluation of avermectins as novel therapeutic agents for alcohol use disorders.
Topics: Alcoholism; Animals; Drug Discovery; Drug Evaluation, Preclinical; Ethanol; Humans; Ivermectin; Receptors, Purinergic P2X4 | 2018 |
Toxicology of Avermectins and Milbemycins (Macrocyclic Lactones) and the Role of P-Glycoprotein in Dogs and Cats.
Topics: Animals; Anthelmintics; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cat Diseases; Cats; Dog Diseases; Dogs; Fat Emulsions, Intravenous; Genotype; Ivermectin; Lactones; Macrolides; Seizures | 2018 |
[Avermectins, intelligently made in China].
Topics: Animals; Anthelmintics; Bacteria; China; Genetic Engineering; Humans; Industrial Microbiology; Ivermectin | 2018 |
Application of Genetic Engineering Approaches to Improve Bacterial Metabolite Production.
Topics: Acremonium; Bacterial Proteins; Biosynthetic Pathways; Cyclohexenes; Fermentation; Gene Expression Regulation, Bacterial; Genetic Engineering; Gentamicins; Hexosamines; Ivermectin; Micromonospora; Natamycin; Protein Biosynthesis; Streptomyces; Transcription, Genetic | 2020 |
6 trial(s) available for avermectin and dextrothyroxine
Article | Year |
---|---|
Duration of persistence of injectable avermectins against sucking lice of cattle.
Topics: Animals; Anoplura; Antiprotozoal Agents; Cattle; Cattle Diseases; Injections; Ivermectin; Lice Infestations; Time Factors | 1996 |
Safety of selamectin in dogs.
Topics: Administration, Oral; Administration, Topical; Animals; Anthelmintics; Antiparasitic Agents; Dirofilariasis; Dog Diseases; Dogs; Dose-Response Relationship, Drug; Ectoparasitic Infestations; Female; Fetus; Ivermectin; Male; Pregnancy; Reproduction | 2000 |
Safety of selamectin in cats.
Topics: Administration, Oral; Animals; Anthelmintics; Antiparasitic Agents; Cats; Dirofilariasis; Dog Diseases; Dogs; Dose-Response Relationship, Drug; Ectoparasitic Infestations; Female; Fetus; Ivermectin; Male; Pregnancy; Reproduction | 2000 |
Evaluation of anthelmintic activity in captive wild ruminants by fecal egg reduction tests and a larval development assay.
Topics: Animals; Antelopes; Anthelmintics; Antibodies, Helminth; Artiodactyla; Benzimidazoles; Deer; Drug Resistance; Feces; Fenbendazole; Haemonchus; Immunity, Innate; Ivermectin; Larva; Levamisole; Nematoda; Nematode Infections; Ostertagia; Parasite Egg Count; Sheep; Sheep Diseases; Trichostrongylus | 2000 |
Selection of different genotype larvae and adult worms for anthelmintic resistance by persistent and short-acting avermectin/milbemycins.
Topics: Administration, Oral; Animals; Anthelmintics; Anti-Bacterial Agents; Delayed-Action Preparations; Drug Resistance; Female; Genotype; Haemonchiasis; Haemonchus; Ivermectin; Larva; Macrolides; Male; Sheep; Sheep Diseases | 2001 |
Efficacy of a new long-acting formulation of ivermectin and other injectable avermectins against induced Psoroptes ovis infestations in cattle.
Topics: Animals; Anthelmintics; Cattle; Cattle Diseases; Injections; Ivermectin; Male; Mite Infestations; Mites; Psoroptidae | 2002 |
488 other study(ies) available for avermectin and dextrothyroxine
Article | Year |
---|---|
Avermectin B1a irreversibly blocks postsynaptic potentials at the lobster neuromuscular junction by reducing muscle membrane resistance.
Topics: Animals; Astacoidea; Cell Membrane; Disaccharides; Ivermectin; Lactones; Membrane Potentials; Nephropidae; Neuromuscular Junction; Species Specificity | 1979 |
Avermectins, new family of potent anthelmintic agents: producing organism and fermentation.
Topics: Anthelmintics; Disaccharides; Fermentation; Ivermectin; Lactones; Streptomyces; Time Factors | 1979 |
Enhancement of in vitro binding and some of the pharmacological properties of diazepam by a novel anthelmintic agent, Avermectin B1a.
Topics: Animals; Anthelmintics; Binding Sites; Diazepam; Disaccharides; Female; Ivermectin; Lactones; Mice; Motor Activity; Rats; Synaptic Membranes | 1979 |
Efficacy of avermectin B1a against microfilariae of Dirofilaria immitis.
Topics: Animals; Anthelmintics; Blood; Dirofilariasis; Disaccharides; Dog Diseases; Dogs; Ivermectin; Lactones; Microfilariae | 1979 |
Anthelmintic activities of B1a fraction of avermectin against gastrointestinal nematodes in calves.
Topics: Animals; Anthelmintics; Cattle; Cattle Diseases; Disaccharides; Gastrointestinal Diseases; Ivermectin; Lactones; Male; Nematode Infections | 1979 |
Expression of a glutamate-activated chloride current in Xenopus oocytes injected with Caenorhabditis elegans RNA: evidence for modulation by avermectin.
Topics: Animals; Anthelmintics; Caenorhabditis elegans; Cell Membrane Permeability; Chloride Channels; Chlorides; Glutamates; Glutamic Acid; Ibotenic Acid; Ion Channel Gating; Ivermectin; Membrane Proteins; Microinjections; Oocytes; Poly A; RNA; Xenopus laevis | 1992 |
Photoaffinity labeling of avermectin binding sites from Caenorhabditis elegans and Drosophila melanogaster.
Topics: Affinity Labels; Animals; Binding Sites; Caenorhabditis; Chloride Channels; Drosophila melanogaster; Ivermectin; Membrane Proteins; Photochemistry; Proteins | 1992 |
Pharmacological profiles of the GABA and acetylcholine receptors from the nematode, Ascaris suum.
Topics: Animals; Ascaris suum; Bicuculline; Cholinergic Antagonists; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Ivermectin; Muscles; Organophosphorus Compounds; Parasympatholytics; Parasympathomimetics; Picrotoxin; Receptors, Cholinergic; Receptors, GABA-A | 1992 |
Bioconversion of avermectin into 27-OH avermectin.
Topics: Anthelmintics; Culture Media; Fermentation; Hydrogen-Ion Concentration; Ivermectin; Kinetics; Methanol; Molecular Structure; Nocardia | 1990 |
Radical-induced oxidation of oxahydrindene (hexahydrobenzofuran) portion of 22,23-dihydroavermectin B1a: identification of autooxidation products.
Topics: Benzofurans; Chemistry, Pharmaceutical; Drug Stability; Free Radicals; Ivermectin; Oxidation-Reduction; Peroxides; tert-Butylhydroperoxide | 1992 |
Synthesis and biological activity of 13-epi-avermectins: potent anthelmintic agents with an increased margin of safety.
Topics: Animals; Anthelmintics; Artemia; Ivermectin; Lethal Dose 50; Magnetic Resonance Spectroscopy; Male; Mice; Sheep; Structure-Activity Relationship | 1992 |
Affinity probes for the avermectin binding proteins.
Topics: Affinity Labels; Animals; Anthelmintics; Artemia; Caenorhabditis elegans; Ivermectin; Ligands; Magnetic Resonance Spectroscopy; Receptors, Drug | 1992 |
Resistance to avermectins and milbemycins.
Topics: Animals; Anthelmintics; Anti-Bacterial Agents; Drug Resistance; Ivermectin; Macrolides; Ostertagia; Sheep; Trichostrongylus | 1992 |
Influence of inhibitors of lipid biosynthesis on the production of avermectins in Streptomyces avermitilis.
Topics: Hypolipidemic Agents; Ivermectin; Lipids; Streptomyces; Triglycerides | 1992 |
Analysis of Streptomyces avermitilis genes required for avermectin biosynthesis utilizing a novel integration vector.
Topics: Base Sequence; Cloning, Molecular; DNA, Bacterial; Escherichia coli; Genetic Complementation Test; Genetic Vectors; Glycosylation; Ivermectin; Methylation; Molecular Sequence Data; Plasmids; Restriction Mapping; Streptomyces; Transformation, Bacterial | 1992 |
Comparative effectiveness of avermectins and deltamethrin in suppressing oviposition in Lucilia cuprina (Diptera: Calliphoridae).
Topics: Animals; Diptera; Ectoparasitic Infestations; Female; Insecticides; Ivermectin; Nitriles; Oviposition; Pyrethrins; Sheep; Sheep Diseases | 1992 |
Nitrogen regulation of fatty acids and avermectins biosynthesis in Streptomyces avermitilis.
Topics: Amino Acids, Branched-Chain; Butyrates; Culture Media; Fatty Acids; Ivermectin; Nitrogen; Quaternary Ammonium Compounds; Streptomyces | 1992 |
Complex organization of the Streptomyces avermitilis genes encoding the avermectin polyketide synthase.
Topics: Erythromycin; Genes, Bacterial; Ivermectin; Macromolecular Substances; Molecular Structure; Multienzyme Complexes; Multigene Family; Streptomyces | 1992 |
Activation of gamma-aminobutyric acid insensitive chloride channels in mouse brain synaptic vesicles by avermectin B1a.
Topics: Animals; Brain; Chloride Channels; gamma-Aminobutyric Acid; In Vitro Techniques; Ion Channel Gating; Ivermectin; Male; Membrane Proteins; Mice; Mice, Inbred ICR; Synaptic Vesicles | 1991 |
Avermectin-sensitive chloride currents induced by Caenorhabditis elegans RNA in Xenopus oocytes.
Topics: Animals; Anthelmintics; Caenorhabditis; Cell Membrane Permeability; Chloride Channels; Chlorides; gamma-Aminobutyric Acid; Ivermectin; Membrane Proteins; Oocytes; Poly A; RNA; RNA, Messenger; Xenopus laevis | 1991 |
Development of a mechanism of action-based screen for anthelmintic microbial metabolites with avermectinlike activity and isolation of milbemycin-producing Streptomyces strains.
Topics: Animals; Anthelmintics; Anti-Bacterial Agents; Brachyura; Caenorhabditis; Cells, Cultured; Chlorides; Ion Channels; Ivermectin; Macrolides; Picrotoxin; Streptomyces | 1991 |
Detection of resistance to ivermectin in Haemonchus contortus.
Topics: Animals; Dose-Response Relationship, Drug; Drug Resistance; Haemonchus; Ivermectin; Larva; Movement | 1991 |
Branched-chain fatty acid requirement for avermectin production by a mutant of Streptomyces avermitilis lacking branched-chain 2-oxo acid dehydrogenase activity.
Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Anthelmintics; Chromatography, High Pressure Liquid; Culture Media; Fatty Acids; Fermentation; Ivermectin; Ketone Oxidoreductases; Multienzyme Complexes; Mutation; Streptomyces | 1991 |
Novel avermectins produced by mutational biosynthesis.
Topics: Animals; Anthelmintics; Caenorhabditis; Carboxylic Acids; Chromatography, High Pressure Liquid; Diptera; Fermentation; Ivermectin; Molecular Structure; Mutation; Streptomyces | 1991 |
Selective production of specific components of avermectins in Streptomyces avermitilis.
Topics: Anthelmintics; Ivermectin; Methyltransferases; Mutation; Phenotype; Streptomyces | 1991 |
Avermectin and avermectin derivatives are antagonists at the 4-aminobutyric acid (GABA) receptor on the somatic muscle cells of Ascaris; is this the site of anthelmintic action?
Topics: Animals; Anthelmintics; Ascaris; GABA-A Receptor Antagonists; Ivermectin; Membrane Potentials | 1990 |
Purification and identification of dTDP-oleandrose, the precursor of the oleandrose units of the avermectins.
Topics: Antiprotozoal Agents; Cell-Free System; Chromatography, High Pressure Liquid; Glycosylation; Hexoses; Indicators and Reagents; Ivermectin; Streptomyces; Thymine Nucleotides | 1990 |
Use of thin-layer chromatography for the testing of avermectins produced by Streptomyces avermitilis strains.
Topics: Antiprotozoal Agents; Chromatography, Thin Layer; Densitometry; Ivermectin; Streptomyces | 1990 |
The actions of avermectin on crayfish nerve and muscle.
Topics: Animals; Astacoidea; Chlorides; Electrophysiology; gamma-Aminobutyric Acid; Ion Channels; Ivermectin; Mechanoreceptors; Muscles | 1986 |
Avermectins: action on target pest species.
Topics: Animals; Anthelmintics; Arthropods; Ion Channels; Ivermectin; Nematoda; Structure-Activity Relationship | 1987 |
Actions of anaesthetics and avermectin on GABAA chloride channels in mammalian dorsal root ganglion neurones.
Topics: Anesthetics; Animals; Cats; Cell Membrane; Chlorides; gamma-Aminobutyric Acid; Ganglia, Spinal; Hydrogen-Ion Concentration; In Vitro Techniques; Ion Channels; Ivermectin; Kinetics; Muscle Relaxation; Neurons; Pentobarbital; Rats | 1989 |
The effect of inorganic phosphate on the production of avermectin in Streptomyces avermitilis.
Topics: Anthelmintics; Culture Media; DNA, Fungal; Fermentation; Glucose; Hydrogen-Ion Concentration; Ivermectin; Phosphates; Streptomyces | 1989 |
Studies on the biosynthesis of avermectins.
Topics: Acetates; Chromatography, High Pressure Liquid; Fermentation; Ivermectin; Mutation; Streptomyces | 1989 |
A chemiluminescent assay for measuring avermectin binding sites.
Topics: Animals; Anthelmintics; Caenorhabditis; Ivermectin; Kinetics; Luminescent Measurements; Luminol; Membranes; Pyridazines | 1989 |
Brine shrimp (Artemia salina) as a convenient bioassay for avermectin analogs.
Topics: Acetonitriles; Animals; Artemia; Drug Evaluation, Preclinical; Ivermectin; Larva; Movement; Solvents | 1989 |
The action of Avermectin (MK 936) on identified central neurones from Helix and its interaction with acetylcholine and gamma-aminobutyric acid (GABA) responses.
Topics: Acetylcholine; Animals; Anthelmintics; Drug Interactions; gamma-Aminobutyric Acid; Helix, Snails; Ivermectin; Kinetics; Lactones; Membrane Potentials; Neural Conduction; Neurons; Sodium | 1986 |
Correlation of myosin light chain phosphorylation and gamma aminobutyric acid receptors in Ascaris suum muscle.
Topics: Acetylcholine; Animals; Anthelmintics; Ascaris; Chlorpromazine; Female; gamma-Aminobutyric Acid; Ivermectin; Kinetics; Muscle Contraction; Muscles; Myosin Subfragments; Myosins; Peptide Fragments; Phosphorylation; Piperazine; Piperazines; Receptors, GABA-A | 1987 |
Syntheses and biological activities of 13-substituted avermectin aglycons.
Topics: Animals; Anthelmintics; Ivermectin; Structure-Activity Relationship | 1989 |
Directed biosynthesis of avermectins.
Topics: Animals; Anthelmintics; Gerbillinae; Ivermectin; Molecular Structure; Streptomyces; Structure-Activity Relationship; Trichostrongylosis | 1989 |
Chitin metabolism: not a target of avermectin/milbemycin activity in insects.
Topics: Animals; Anti-Bacterial Agents; Chitin; Chitin Synthase; Chitinases; Glucosyltransferases; Insecta; Insecticides; Ivermectin; Kinetics; Lactones; Macrolides; Species Specificity | 1987 |
Isolation and preliminary characterization of lytic and lysogenic phages with wide host range within the streptomycetes.
Topics: Anthelmintics; Bacteriophages; DNA Restriction Enzymes; DNA, Viral; Ivermectin; Lactones; Lysogeny; Nucleic Acid Hybridization; Streptomyces; Transduction, Genetic; Viral Plaque Assay | 1985 |
Biosynthesis of the avermectins by Streptomyces avermitilis. Incorporation of labeled precursors.
Topics: Acetates; Acetic Acid; Anthelmintics; Carbon Dioxide; Carbon Radioisotopes; Glucose; Ivermectin; Lactones; Methionine; Propionates; Streptomyces | 1986 |
Anticonvulsant effects of avermectin in DBA/2 mice and rat.
Topics: Animals; Anticonvulsants; Cefazolin; Electroshock; Ivermectin; Male; Mice; Mice, Inbred DBA; Pentylenetetrazole; Rats; Rats, Inbred Strains; Seizures; Sound | 1988 |
Toxic baiting of the Western yellowjacket (Hymenoptera: Vespidae) in Hawaii.
Topics: Animals; Color Perception; Diazinon; Fish Products; Hawaii; Hymenoptera; Insect Control; Insecticides; Ivermectin; Seasons; Tuna; Wasps | 1988 |
Involvement of glucose catabolism in avermectin production by Streptomyces avermitilis.
Topics: Anthelmintics; Culture Media; Fermentation; Glucose; Ivermectin; Pentose Phosphate Pathway; Phosphogluconate Dehydrogenase; Streptomyces | 1988 |
Effect of avermectin B1 and benzimidazole anthelmintics on worm egg output of treated cattle.
Topics: Albendazole; Animals; Anthelmintics; Benzimidazoles; Cattle; Cattle Diseases; Feces; Fenbendazole; Ivermectin; Nematode Infections; Parasite Egg Count | 1988 |
Avermectin toxicity in calves and an evaluation of picrotoxin as an antidote.
Topics: Animals; Anthelmintics; Antidotes; Cattle; Cattle Diseases; Drug Evaluation; Female; Ivermectin; Male; Picrotoxin | 1988 |
Avermectin B1 toxicity in a herd of Murray Grey cattle.
Topics: Animals; Anthelmintics; Cattle; Cattle Diseases; Central Nervous System Diseases; Female; Ivermectin; Male | 1987 |
"Streptomyces avermitilis" mutants defective in methylation of avermectins.
Topics: Adenosine; Anthelmintics; Bacterial Proteins; Ivermectin; Methylation; Methyltransferases; Mutation; Streptomyces | 1987 |
Genetic studies of avermectin biosynthesis in Streptomyces avermitilis.
Topics: Chemical Phenomena; Chemistry; Chromosome Mapping; Chromosomes, Bacterial; Crosses, Genetic; Genes, Bacterial; Genetic Linkage; Ivermectin; Mutation; Phenotype; Recombination, Genetic; Streptomyces | 1987 |
Avermectin B2 O-methyltransferase activity in "Streptomyces avermitilis" mutants that produce increased amounts of the avermectins.
Topics: Bacterial Proteins; Ivermectin; Kinetics; Lactones; Methyltransferases; S-Adenosylmethionine; Streptomyces | 1986 |
Anthelmintic drugs.
Topics: Amidines; Animals; Anthelmintics; Benzimidazoles; Cats; Cattle; Diethylcarbamazine; Dogs; Helminthiasis; Helminthiasis, Animal; Horses; Ivermectin; Lactones; Levamisole; Morantel; Organophosphorus Compounds; Piperazine; Piperazines; Praziquantel; Pyrantel; Salicylanilides; Sheep; Tetramisole | 1986 |
Demethylavermectins. Biosynthesis, isolation and characterization.
Topics: Adenosine; Anthelmintics; Insecticides; Ivermectin; Lactones; Methyltransferases; Streptomyces | 1985 |
The lack of antifungal activity by avermectin B1a.
Topics: Antifungal Agents; Cell Wall; Chitin; Ivermectin; Lactones; Microbial Sensitivity Tests; Mucor; Oligomycins | 1985 |
Evidence for association of a high affinity avermectin binding site with the benzodiazepine receptor.
Topics: Animals; Binding Sites; Binding, Competitive; Cell Membrane; Cerebellar Cortex; Chlorides; Flunitrazepam; In Vitro Techniques; Ivermectin; Lactones; Picrotoxin; Rats; Receptors, Cell Surface; Receptors, GABA-A; Sesterterpenes; Temperature | 1984 |
Avermectin modulation of GABA binding to membranes of rat brain, brine shrimp and a fungus, Mucor miehei.
Topics: Animals; Bicuculline; Brain; Chlorides; Decapoda; gamma-Aminobutyric Acid; Ivermectin; Kinetics; Lactones; Male; Mucor; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Sodium | 1984 |
[35S]tert.-butylbicyclophosphorothionate and avermectin bind to different sites associated with the gamma- aminobutyric acid-benzodiazepine receptor complex.
Topics: Animals; Binding Sites; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Cerebellum; Cerebral Cortex; Hippocampus; Hydrogen-Ion Concentration; Ivermectin; Lactones; Membranes; Rats; Receptors, GABA-A | 1984 |
The effects of avermectin and drugs related to acetylcholine and 4-aminobutyric acid on neurotransmission in Ascaris suum.
Topics: Acetylcholine; Animals; Anthelmintics; Ascaris; Curare; Electric Stimulation; gamma-Aminobutyric Acid; In Vitro Techniques; Ivermectin; Lactones; Motor Neurons; Muscimol; Piperazine; Piperazines; Synaptic Transmission | 1984 |
Interaction of avermectins with [3H]beta-carboline-3-carboxylate ethyl ester and [3H]diazepam binding sites in rat brain cortical membranes.
Topics: Animals; Binding Sites; Carbolines; Cell Membrane; Cerebral Cortex; Diazepam; Indoles; Ivermectin; Lactones; Rats; Receptors, Drug; Receptors, GABA-A | 1982 |
Triphasic locomotor response of a plant-parasitic nematode to avermectin: inhibition by the GABA antagonists bicuculline and picrotoxin.
Topics: Animals; Anthelmintics; Bicuculline; Ivermectin; Lactones; Motor Activity; Nematoda; Picrotoxin; Receptors, Cell Surface; Receptors, GABA-A; Synaptic Transmission | 1984 |
Toxicity of avermectin B1 to larval yellowjackets, Vespula maculifrons (Hymenoptera: Vespidae).
Topics: Animals; Hymenoptera; Insecticides; Ivermectin; Lactones; Lethal Dose 50; Wasps | 1984 |
Direct determination of avermectins in plasma at nanogram levels by high-performance liquid chromatography.
Topics: Animals; Cattle; Chromatography, High Pressure Liquid; Isomerism; Ivermectin; Lactones; Microchemistry; Spectrometry, Fluorescence; Time Factors | 1983 |
Inhibition of chitin metabolism by avermectin in susceptible organisms.
Topics: Animals; Artemia; Bacteria; Chitin; Chitinases; Fungi; Ivermectin; Lactones; Microbial Sensitivity Tests; Mucor; Streptomyces | 1984 |
Ivermectin, a new broad-spectrum antiparasitic agent.
Topics: Animals; Anthelmintics; Cattle; Disaccharides; Helminthiasis; Intestinal Diseases, Parasitic; Ivermectin; Lactones; Sheep | 1980 |
The avermectin complex: a new horizon in anthelmintic therapy.
Topics: Animals; Cattle; Disaccharides; Dogs; Horses; Ivermectin; Lactones; Nematode Infections; Sheep | 1981 |
Avermectin acyl derivatives with anthelmintic activity.
Topics: Animals; Anthelmintics; Chemical Phenomena; Chemistry; Gerbillinae; Haemonchiasis; Ivermectin; Lactones; Ostertagiasis; Sheep; Trichostrongylosis | 1982 |
The effects of some avermectins on the growth of Brugia pahangi.
Topics: Animals; Anthelmintics; Brugia; Female; Filarioidea; Gerbillinae; Ivermectin; Lactones; Male | 1982 |
Treatment of psoroptic mange with avermectins.
Topics: Administration, Topical; Animals; Disaccharides; Injections, Subcutaneous; Ivermectin; Lactones; Mite Infestations; Rabbits | 1980 |
Control of ticks systemically with Merck MK-933, an avermectin.
Topics: Animals; Cattle; Cattle Diseases; Ivermectin; Lactones; Tick Infestations | 1981 |
Efficacy of thiabendazole, levamisole hydrochloride and the major natural avermectins against Trichostrongylus colubriformis in the gerbil (Meriones unguiculatus).
Topics: Animals; Anthelmintics; Gerbillinae; Ivermectin; Lactones; Levamisole; Male; Rodent Diseases; Thiabendazole; Trichostrongyloidiasis; Trichostrongylosis | 1981 |
Insecticidal activity of the avermectins.
Topics: Animals; Anthelmintics; Diptera; Disaccharides; Ivermectin; Lactones; Larva; Sheep; Sheep Diseases | 1980 |
Determination of avermectins in plasma at nanogram levels using high-performance liquid chromatography with fluorescence detection.
Topics: Animals; Anthelmintics; Cattle; Chromatography, High Pressure Liquid; Disaccharides; Ivermectin; Lactones; Spectrometry, Fluorescence | 1980 |
Construction of a single component producer from the wild type avermectin producer Streptomyces avermitilis.
Topics: Anthelmintics; Chromatography, High Pressure Liquid; Ivermectin; Streptomyces | 1995 |
Avermectin inhibition of larval development in Haemonchus contortus--effects of ivermectin resistance.
Topics: Animals; Anthelmintics; Benzimidazoles; Dose-Response Relationship, Drug; Drug Resistance; Haemonchus; Ivermectin; Larva; Levamisole; Male; Parasite Egg Count; Rafoxanide; Sheep | 1995 |
Characterisation of an avermectin resistant strain of Australian Haemonchus contortus.
Topics: Animals; Anthelmintics; Anti-Bacterial Agents; Australia; Benzimidazoles; Drug Resistance; Drug Therapy, Combination; Female; Haemonchiasis; Haemonchus; Ivermectin; Levamisole; Macrolides; Male; Salicylanilides; Sheep; Sheep Diseases | 1995 |
The mechanism of action of avermectins in Caenorhabditis elegans: correlation between activation of glutamate-sensitive chloride current, membrane binding, and biological activity.
Topics: Animals; Anthelmintics; Anti-Bacterial Agents; Caenorhabditis elegans; Chloride Channels; Drug Synergism; Electrophysiology; Glutamic Acid; Ion Channel Gating; Ivermectin; Macrolides; Membrane Potentials | 1995 |
A second branched-chain alpha-keto acid dehydrogenase gene cluster (bkdFGH) from Streptomyces avermitilis: its relationship to avermectin biosynthesis and the construction of a bkdF mutant suitable for the production of novel antiparasitic avermectins.
Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Amino Acid Sequence; Anthelmintics; Base Sequence; Cloning, Molecular; Ivermectin; Ketone Oxidoreductases; Molecular Sequence Data; Multienzyme Complexes; Multigene Family; Phenotype; Sequence Deletion; Sequence Homology, Amino Acid; Streptomyces | 1995 |
[An experimental evaluation of the cutaneous action of the preparation Bulmektin].
Topics: Animals; Anthelmintics; Blood; Dose-Response Relationship, Drug; Female; Guinea Pigs; Ivermectin; Leukocytes; Male; Rats; Rats, Wistar; Skin; Time Factors | 1994 |
Production of 6,8a-seco-6,8a-deoxy derivatives of avermectins by a mutant strain of Streptomyces avermitilis.
Topics: Anthelmintics; Antiprotozoal Agents; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Cloning, Molecular; DNA, Bacterial; Genes, Bacterial; Ivermectin; Mutagenesis; Mutation; Streptomyces | 1995 |
Production of a new methylated 6,8a-seco-6,8a-deoxy derivative of the avermectins by a transformant strain of Streptomyces avermitilis.
Topics: Chemical Phenomena; Chemistry, Physical; Chromatography, High Pressure Liquid; Genes, Bacterial; Ivermectin; Magnetic Resonance Spectroscopy; Methylation; Mutation; Streptomyces; Transformation, Bacterial | 1995 |
Direct production of 5-oxo derivatives of avermectins by a recombinant strain of Streptomyces avermitilis.
Topics: Anthelmintics; Antiprotozoal Agents; Frameshift Mutation; Ivermectin; Oximes; Recombination, Genetic; Spectrophotometry; Streptomyces | 1995 |
Cloning of an avermectin-sensitive glutamate-gated chloride channel from Caenorhabditis elegans.
Topics: Amino Acid Sequence; Animals; Base Sequence; Caenorhabditis elegans; Cell Membrane Permeability; Cells, Cultured; Chloride Channels; Cloning, Molecular; DNA, Complementary; Electrophysiology; Escherichia coli; Glutamic Acid; Humans; Ion Channel Gating; Ivermectin; Molecular Sequence Data; Oocytes; Sequence Homology, Amino Acid; Xenopus | 1994 |
Correlation of the avermectin polyketide synthase genes to the avermectin structure. Implications for designing novel avermectins.
Topics: Anthelmintics; Anti-Bacterial Agents; Antiprotozoal Agents; Drug Design; Erythromycin; Genes, Bacterial; Genetic Engineering; Ivermectin; Macrolides; Molecular Structure; Multienzyme Complexes; Streptomyces | 1994 |
Characterization of a Streptomyces-lividans-type site-specific DNA modification system in the avermectin-producer Streptomyces avermitilis permits investigation of two novel giant linear plasmids, pSA1 and pSA2.
Topics: Bacterial Proteins; DNA Restriction-Modification Enzymes; DNA, Bacterial; Electrophoresis, Gel, Pulsed-Field; Ivermectin; Nucleic Acid Hybridization; Plasmids; Species Specificity; Streptomyces | 1994 |
Immunoaffinity purification of avermectin-binding proteins from the free-living nematode Caenorhabditis elegans and the fruitfly Drosophila melanogaster.
Topics: Animals; Antibodies, Monoclonal; Caenorhabditis elegans; Carrier Proteins; Chromatography, Affinity; Chromatography, Gel; Drosophila melanogaster; Electrophoresis, Polyacrylamide Gel; Ivermectin; Precipitin Tests | 1994 |
Activation of Cl- channels by avermectin in rat cultured hippocampal neurons.
Topics: Animals; Animals, Newborn; Anthelmintics; Cells, Cultured; Chloride Channels; Electrophysiology; Hippocampus; Ivermectin; Membrane Potentials; Neurons; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA-A; Sesterterpenes | 1993 |
Milbemycin derivatives: modification at the C-5 position.
Topics: Animals; Anthelmintics; Anti-Bacterial Agents; Ivermectin; Macrolides; Nippostrongylus; Structure-Activity Relationship | 1994 |
Microbial conversion of avermectins by Saccharopolyspora erythraea: hydroxylation at C-27.
Topics: Antiprotozoal Agents; Chromatography, High Pressure Liquid; Hydroxylation; Ivermectin; Magnetic Resonance Spectroscopy; Molecular Structure; Saccharopolyspora | 1994 |
Microbial conversion of avermectins by Saccharopolyspora erythraea: glycosylation at C-4' and C-4''.
Topics: Anthelmintics; Biotransformation; Chromatography, DEAE-Cellulose; Chromatography, High Pressure Liquid; Disaccharides; Glycosides; Glycosyltransferases; Ivermectin; Magnetic Resonance Spectroscopy; Saccharopolyspora; Uridine Diphosphate Glucose | 1993 |
Special issue: Environmental impact of avermectin usage in livestock.
Topics: Animals; Animals, Domestic; Environmental Pollution; Ivermectin | 1993 |
Effects of avermectin residues in cattle dung on dung beetle (Coleoptera: Scarabaeidae) reproduction and survival.
Topics: Animals; Anthelmintics; Australia; Biodegradation, Environmental; Cattle; Coleoptera; Feces; Ivermectin; Reproduction; Seasons; Temperature; Time Factors | 1993 |
Research recommendations.
Topics: Animals; Anthelmintics; Environmental Pollution; Feces; Invertebrates; Ivermectin; Parasitic Diseases; Parasitic Diseases, Animal; Soil Pollutants | 1993 |
Transposon mutagenesis by Tn4560 and applications with avermectin-producing Streptomyces avermitilis.
Topics: Anthelmintics; Chromosomes, Bacterial; DNA Transposable Elements; Ivermectin; Mutagenesis, Insertional; Oligomycins; Plasmids; Recombination, Genetic; Sequence Homology, Nucleic Acid; Streptomyces | 1993 |
Instability of the production of avermectins, sporulation, and pigmentation in Streptomyces avermitilis.
Topics: Ivermectin; Microscopy, Electron, Scanning; Phenotype; Pigmentation; Spores, Bacterial; Streptomyces | 1993 |
Deletion analysis of the avermectin biosynthetic genes of Streptomyces avermitilis by gene cluster displacement.
Topics: Anthelmintics; Antiprotozoal Agents; Base Sequence; Chromosome Mapping; Drug Resistance, Microbial; Escherichia coli; Genes, Bacterial; Genetic Complementation Test; Genetic Techniques; Glycosylation; Ivermectin; Methylation; Molecular Sequence Data; Multigene Family; Phenotype; Plasmids; Recombination, Genetic; Sequence Deletion; Streptomyces | 1993 |
[Effect of nitrogen-containing compounds on the biosynthesis of avermectins].
Topics: Amino Acids; Ammonium Chloride; Anthelmintics; Insecticides; Ivermectin; Mutation; Nitrogen Compounds; Streptomyces | 1995 |
The prevalence of anthelmintic resistance in nematode parasites of sheep in southern Latin America: Uruguay.
Topics: Agriculture; Animals; Benzimidazoles; Demography; Drug Resistance, Multiple; Haemonchus; Ivermectin; Levamisole; Nematoda; Nematode Infections; Ostertagia; Sheep; Sheep Diseases; Temperature; Trichostrongylus; Uruguay | 1996 |
Histology of the skin and determination of blood and serum parameters during the recovery phase of sarcoptic manage in cattle after avermectin (Ivomec) treatment.
Topics: Animals; Cattle; Cattle Diseases; Female; Immunoglobulin G; Immunoglobulin M; Ivermectin; Mite Infestations; Pesticides; Skin | 1996 |
Identification of a Drosophila melanogaster glutamate-gated chloride channel sensitive to the antiparasitic agent avermectin.
Topics: Animals; Base Sequence; Chloride Channel Agonists; Chloride Channels; DNA Primers; Drosophila melanogaster; Electric Conductivity; Excitatory Amino Acid Agonists; Gene Expression; Genes, Insect; Glutamates; Ion Channel Gating; Ivermectin; Molecular Sequence Data; Receptors, Glutamate; RNA, Messenger; Sequence Alignment; Sequence Homology, Amino Acid; Xenopus laevis | 1996 |
[Activity of threonine deaminase and biosynthesis of avermectins in the culture of Streptomyces avermitilis].
Topics: Ammonium Chloride; Drug Resistance, Microbial; Isoleucine; Ivermectin; Mutation; Streptomyces; Threonine; Threonine Dehydratase; Valine | 1995 |
Cryopreservation of the first-stage larvae of trichostrongylid nematode parasites.
Topics: Animals; Anthelmintics; Benzimidazoles; Cryopreservation; Drug Resistance; Evaluation Studies as Topic; Haemonchus; Ivermectin; Larva; Levamisole; Male; Ostertagia; Sheep; Trichostrongyloidea; Trichostrongylus | 1995 |
Ecotoxicity of the avermectins: a reply to Forbes.
Topics: Animals; Anti-Bacterial Agents; Antiprotozoal Agents; Cattle; Cattle Diseases; Ecosystem; Environmental Monitoring; Ivermectin; Macrolides; Parasitic Diseases; Parasitic Diseases, Animal; Safety | 1996 |
Cytoprotection of kidney epithelial cells by compounds that target amino acid gated chloride channels.
Topics: Adenosine Triphosphate; Amino Acids; Animals; Antiprotozoal Agents; Binding Sites; Borates; Calcium; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cell Line; Chloride Channels; Chlorides; Dogs; Epithelial Cells; Epithelium; Fluorescent Dyes; Gluconates; Ion Channel Gating; Ionomycin; Ionophores; Ivermectin; Kidney Tubules, Distal; L-Lactate Dehydrogenase; Microscopy, Electron; Receptors, Glycine; Strychnine; Sucrose; Zinc | 1996 |
Efficacy in sheep and pharmacokinetics in cattle that led to the selection of eprinomectin as a topical endectocide for cattle.
Topics: Administration, Topical; Animals; Anthelmintics; Anti-Bacterial Agents; Cattle; Cattle Diseases; Drug Design; Female; Humans; Ivermectin; Lactation; Macrolides; Molecular Structure; Nematoda; Nematode Infections; Sheep; Species Specificity; Structure-Activity Relationship | 1996 |
Eprinomectin: a novel avermectin for use as a topical endectocide for cattle.
Topics: Administration, Topical; Animals; Anthelmintics; Cattle; Cattle Diseases; Diptera; Drug Design; Female; Helminths; Ivermectin; Lactation; Mite Infestations; Mites; Nematode Infections; Sheep; Sheep Diseases; Structure-Activity Relationship | 1996 |
Adult and infant abamectin exposures following Avert 310 and pressurized gel crack and crevice treatment.
Topics: Adult; Air Pollution, Indoor; Animals; California; Chromatography, High Pressure Liquid; Cockroaches; Dose-Response Relationship, Drug; Dust; Environmental Exposure; Excitatory Amino Acid Agonists; Filtration; Humans; Infant, Newborn; Insecticides; Ivermectin; Pest Control; Pesticide Residues; Polytetrafluoroethylene; Random Allocation; Risk Assessment; Skin Absorption; Synaptic Transmission | 1997 |
Evolutionary relationship of the ligand-gated ion channels and the avermectin-sensitive, glutamate-gated chloride channels.
Topics: Animals; Antinematodal Agents; Caenorhabditis elegans; Chloride Channels; Genes, Helminth; Glutamic Acid; Ion Channel Gating; Ivermectin; Ligands; Molecular Sequence Data; Phylogeny; Sequence Alignment; Sequence Analysis, DNA | 1997 |
Avermectin toxicity in the dog.
Topics: Animals; Dogs; Insecticides; Ivermectin | 1997 |
Avermectin toxicity in the dog.
Topics: Animals; Dogs; Insecticides; Ivermectin | 1997 |
Target size analysis of an avermectin binding site from Drosophila melanogaster.
Topics: Acetylcholinesterase; Animals; Binding Sites; Chloride Channels; Drosophila melanogaster; Insecticides; Ivermectin | 1997 |
Reporter gene constructs suggest that the Caenorhabditis elegans avermectin receptor beta-subunit is expressed solely in the pharynx.
Topics: Amino Acid Sequence; Animals; Caenorhabditis elegans; Chloride Channels; Genes, Reporter; Ivermectin; Molecular Sequence Data | 1997 |
Avermectin toxicity in the dog.
Topics: Animals; Disease Reservoirs; Dog Diseases; Dogs; Euthanasia; Foxes; Insecticides; Ivermectin; Scabies; Veterinary Medicine | 1997 |
The Caenorhabditis elegans avermectin resistance and anesthetic response gene unc-9 encodes a member of a protein family implicated in electrical coupling of excitable cells.
Topics: Alleles; Amino Acid Sequence; Anesthetics; Animals; Anthelmintics; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Cloning, Molecular; Female; Gap Junctions; Helminth Proteins; Insecticide Resistance; Ivermectin; Membrane Proteins; Molecular Sequence Data; Motor Activity; Mutation; Oviposition | 1997 |
Genetic and biochemical evidence for a novel avermectin-sensitive chloride channel in Caenorhabditis elegans. Isolation and characterization.
Topics: Amino Acid Sequence; Animals; Base Sequence; Caenorhabditis elegans; Chloride Channels; Chromosome Mapping; Chromosomes, Artificial, Yeast; Ivermectin; Molecular Sequence Data; Phenotype; Ribonuclease H; RNA, Messenger; Xenopus | 1997 |
Engineering broader specificity into an antibiotic-producing polyketide synthase.
Topics: Anti-Bacterial Agents; Carboxylic Acids; Cloning, Molecular; Erythromycin; Fermentation; Ivermectin; Multienzyme Complexes; Promoter Regions, Genetic; Protein Engineering; Protein Multimerization; Saccharopolyspora; Streptomyces; Substrate Specificity | 1998 |
Cloning of the gene encoding avermectin B 5-O-methyltransferase in avermectin-producing Streptomyces avermitilis.
Topics: Amino Acid Sequence; Bacterial Proteins; Base Sequence; Cloning, Molecular; DNA Mutational Analysis; Ivermectin; Methyltransferases; Molecular Sequence Data; Multigene Family; Mutation; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Streptomyces | 1998 |
Evidence of multiple mechanisms of avermectin resistance in haemonchus contortus--comparison of selection protocols.
Topics: Animals; Anthelmintics; Drug Resistance; Haemonchiasis; Haemonchus; Ivermectin; Larva; Sheep; Sheep Diseases | 1998 |
The relationship between parasite counts, lesions, antibody titres and daily weight gains in Psoroptes ovis infested cattle.
Topics: Animals; Anti-Bacterial Agents; Antibodies; Body Weight; Cattle; Cattle Diseases; Enzyme-Linked Immunosorbent Assay; Female; Insecticides; Ivermectin; Macrolides; Male; Mite Infestations; Mites; Regression Analysis; Weight Gain | 1998 |
Cloning and localisation of an avermectin receptor-related subunit from Haemonchus contortus.
Topics: Amino Acid Sequence; Animals; Anthelmintics; Base Sequence; Blotting, Western; Chloride Channels; Cloning, Molecular; DNA, Complementary; Female; Fluorescent Antibody Technique; Genes, Helminth; Haemonchus; Helminth Proteins; Ivermectin; Molecular Sequence Data; Motor Neurons; Receptors, Glutamate; Sequence Alignment; Sheep | 1998 |
Survey of malathion resistance and avermectin susceptibility in field populations of Drosophila melanogaster (Diptera: Drosophilidae) and D. simulans.
Topics: Animals; Drosophila; Drosophila melanogaster; Insecticide Resistance; Insecticides; Ivermectin; Malathion | 1998 |
Synthesis of gem-difluoro-avermectin derivatives: potent anthelmintic and anticonvulsant agents.
Topics: Animals; Anthelmintics; Anticonvulsants; Epilepsy; Ivermectin; Mice; Molecular Structure | 1998 |
Haemonchus contortus: sequence heterogeneity of internucleotide binding domains from P-glycoproteins.
Topics: Amino Acid Sequence; Animals; Anthelmintics; Anti-Bacterial Agents; ATP Binding Cassette Transporter, Subfamily B; Base Sequence; Blotting, Northern; Blotting, Southern; Cloning, Molecular; DNA Primers; DNA Probes; DNA, Helminth; Drug Resistance, Multiple; Genetic Variation; Haemonchus; Helminth Proteins; Ivermectin; Macrolides; Molecular Sequence Data; Polymerase Chain Reaction; RNA, Helminth; Sequence Alignment; Sequence Homology, Amino Acid; Sequence Homology, Nucleic Acid; Sheep | 1999 |
Confirmation of avermectin residues in food matrices with negative-ion atmospheric pressure chemical ionization liquid chromatography/mass spectrometry.
Topics: Animals; Anthelmintics; Cattle; Gas Chromatography-Mass Spectrometry; Ivermectin; Liver; Meat; Milk; Pesticide Residues; Salmon | 1999 |
Resistance of field isolates of Trichostrongylus colubriformis and Ostertagia circumcincta to ivermectin.
Topics: Administration, Oral; Animals; Anthelmintics; Drug Resistance; Feces; Goat Diseases; Goats; Ivermectin; Lethal Dose 50; Ostertagia; Ostertagiasis; Parasite Egg Count; Sheep; Sheep Diseases; Time Factors; Trichostrongylosis; Trichostrongylus | 1999 |
[Action of avermectins on lymphoid leukemia P-388 cells in vitro].
Topics: Animals; Antineoplastic Agents; Antiparasitic Agents; Drug Screening Assays, Antitumor; Insecticides; Ivermectin; Leukemia, Lymphoid; Male; Mice; Mice, Inbred DBA; Streptomyces; Tumor Cells, Cultured | 1999 |
Multiresidue method for the determination of avermectin and moxidectin residues in the liver using HPLC with fluorescence detection.
Topics: Animals; Anthelmintics; Anti-Bacterial Agents; Antiprotozoal Agents; Chromatography, High Pressure Liquid; Drug Residues; Ivermectin; Liver; Macrolides | 1998 |
Organization of the biosynthetic gene cluster for the polyketide anthelmintic macrolide avermectin in Streptomyces avermitilis.
Topics: Anthelmintics; Anti-Bacterial Agents; Base Sequence; DNA, Bacterial; Genetic Engineering; Ivermectin; Macrolides; Models, Chemical; Molecular Sequence Data; Multienzyme Complexes; Multigene Family; Streptomyces | 1999 |
Pharmacology of anthelmintic resistance in cyathostomes: will it occur with the avermectin/milbemycins?
Topics: Animals; Anthelmintics; Anti-Bacterial Agents; Drug Resistance; Horse Diseases; Horses; Ivermectin; Macrolides; Strongylida Infections; Strongyloidea | 1999 |
[Assessment of the mutagenic activity of aversectin C].
Topics: Anaphase; Animals; Anti-Bacterial Agents; Bone Marrow Cells; Ivermectin; Lethal Dose 50; Male; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mitosis; Mutagenicity Tests; Mutagens; Rats; Salmonella typhimurium | 1999 |
Genes encoding acyl-CoA dehydrogenase (AcdH) homologues from Streptomyces coelicolor and Streptomyces avermitilis provide insights into the metabolism of small branched-chain fatty acids and macrolide antibiotic production.
Topics: Acyl-CoA Dehydrogenase; Acyl-CoA Dehydrogenases; Amino Acid Sequence; Animals; Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Cloning, Molecular; Electrophoresis, Polyacrylamide Gel; Fatty Acids; Gene Deletion; Humans; Ivermectin; Macrolides; Molecular Sequence Data; Polymerase Chain Reaction; Rats; Sequence Analysis, DNA; Streptomyces | 1999 |
Absence or pharmacological blocking of placental P-glycoprotein profoundly increases fetal drug exposure.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carbon Radioisotopes; Crosses, Genetic; Digoxin; Female; Heterozygote; Insecticides; Ivermectin; Male; Maternal-Fetal Exchange; Mice; Mice, Knockout; Mice, Mutant Strains; Paclitaxel; Placenta; Pregnancy; Saquinavir; Tissue Distribution | 1999 |
Inheritance of avermectin resistance in Haemonchus contortus.
Topics: Animals; Anthelmintics; Crosses, Genetic; Dose-Response Relationship, Drug; Drug Resistance; Female; Genes, Dominant; Genes, Helminth; Genetic Linkage; Haemonchus; Ivermectin; Larva; Male; Sex Chromosomes; Sex Factors; Sheep | 2000 |
Selective cytostatic and neurotoxic effects of avermectins and activation of the GABAalpha receptors.
Topics: Animals; Bicuculline; Cell Differentiation; Cell Division; Dose-Response Relationship, Drug; GABA Agonists; GABA Antagonists; Ivermectin; Male; Neuroblastoma; Neurons; Neurotoxins; Pentobarbital; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA-A; Septal Nuclei; Tumor Cells, Cultured | 1999 |
Mass spectrometry of avermectins: structural determination of two new derivatives of Ivermectin B(1a).
Topics: Antiprotozoal Agents; Ivermectin; Mass Spectrometry; Streptomyces | 2000 |
Avermectin chemistry and action: ester- and ether-type candidate photoaffinity probes.
Topics: Animals; Anthelmintics; Brain; Female; Houseflies; Insecticides; Ivermectin; Magnetic Resonance Spectroscopy; Male; Mice; Photoaffinity Labels; Radioligand Assay; Structure-Activity Relationship | 2000 |
Avermectins and flea control: structure-activity relationships and the selection of selamectin for development as an endectocide for companion animals.
Topics: Animals; Cats; Dogs; Female; Insecticides; Ivermectin; Magnetic Resonance Spectroscopy; Male; Molecular Structure; Siphonaptera; Spectrometry, Mass, Electrospray Ionization; Structure-Activity Relationship | 2000 |
Validation and robustness testing of a HPLC method for the determination of avermectins and moxidectin in animal liver samples using an alumina column clean-up.
Topics: Aluminum; Animals; Anthelmintics; Anti-Bacterial Agents; Cattle; Chromatography, High Pressure Liquid; Drug Residues; Ivermectin; Liver; Macrolides; Sensitivity and Specificity | 2000 |
Anticonvulsant and adverse effects of avermectin analogs in mice are mediated through the gamma-aminobutyric acid(A) receptor.
Topics: Animals; Anticonvulsants; Cells, Cultured; Cerebral Cortex; Female; Ivermectin; Male; Mice; Rats; Receptors, GABA-A; Receptors, Glycine; Recombinant Proteins; Xenopus | 2000 |
A questionnaire survey on the practices adopted to control gastrointestinal nematode parasitism in dairy goat farms in France.
Topics: Animal Husbandry; Animals; Anthelmintics; Anti-Bacterial Agents; Benzimidazoles; Female; France; Gastrointestinal Diseases; Goat Diseases; Goats; Ivermectin; Levamisole; Macrolides; Nematode Infections; Pyrantel; Surveys and Questionnaires | 2000 |
Elimination of Sarcoptes scabiei in pig herds by single or double administrations of an avermectin.
Topics: Animals; Female; Injections, Intramuscular; Insecticides; Ivermectin; Male; Sarcoptes scabiei; Scabies; Swine; Swine Diseases | 2000 |
[Cytotoxic and cytostatic effect of avermectines on tumor cells in vitro].
Topics: Animals; Antibiotics, Antineoplastic; Carcinoma, Ehrlich Tumor; Cell Division; Humans; Ivermectin; Laryngeal Neoplasms; Mice; Multiple Myeloma; Neoplasms, Glandular and Epithelial; Tumor Cells, Cultured | 2000 |
Multi-residue analysis of avermectins and moxidectin by ion-trap LC-MSn.
Topics: Animals; Anthelmintics; Anti-Bacterial Agents; Cattle; Drug Residues; Insecticides; Ivermectin; Liver; Macrolides; Mass Spectrometry; Meat | 2001 |
[Determination of avermictin in avermictin tablet by high performance liquid chromatography].
Topics: Animals; Anthelmintics; Antiprotozoal Agents; Chromatography, High Pressure Liquid; Ivermectin; Tablets | 1998 |
[Genetic analysis of biosynthesis of polyketide compound in Streptomyces avermitilis].
Topics: Animals; Humans; Ivermectin; Multienzyme Complexes; Streptomyces | 2001 |
Multi-residue analysis of avermectins in swine liver by immunoaffinity extraction and liquid chromatography-mass spectrometry.
Topics: Animals; Anthelmintics; Antiprotozoal Agents; Chromatography, Affinity; Chromatography, Liquid; Immunosorbents; Ivermectin; Liver; Mass Spectrometry; Molecular Structure; Sensitivity and Specificity; Swine | 2001 |
Development and optimisation of an improved derivatisation procedure for the determination of avermectins and milbemycins in bovine liver.
Topics: Animals; Anti-Bacterial Agents; Antiprotozoal Agents; Cattle; Drug Residues; Food Contamination; Ivermectin; Liver; Macrolides; Mass Spectrometry | 2001 |
Comparison of various liquid chromatographic methods for the analysis of avermectin residues in citrus fruits.
Topics: Chromatography, Liquid; Citrus; Drug Residues; Ivermectin; Sensitivity and Specificity; Spectrometry, Fluorescence; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet | 2001 |
Effect of avermectins on Ca2+-dependent Cl- currents in plasmalemma of Chara corallina cells.
Topics: Calcium; Cell Membrane; Chloride Channels; Chlorides; Dose-Response Relationship, Drug; Electrophysiology; Eukaryota; Ivermectin; Patch-Clamp Techniques | 2001 |
Insights about the biosynthesis of the avermectin deoxysugar L-oleandrose through heterologous expression of Streptomyces avermitilis deoxysugar genes in Streptomyces lividans.
Topics: Anthelmintics; Combinatorial Chemistry Techniques; Deoxy Sugars; Gene Expression; Hexoses; Ivermectin; Multigene Family; Plasmids; Protein Engineering; Racemases and Epimerases; Stereoisomerism; Streptomyces | 2001 |
Anthelmintic resistance on an organized sheep farm in India.
Topics: Animals; Anthelmintics; Benzimidazoles; Drug Resistance; Feces; Female; India; Ivermectin; Levamisole; Parasitic Diseases, Animal; Parasitic Sensitivity Tests; Rafoxanide; Salicylanilides; Seasons; Sheep; Sheep Diseases; Tetramisole | 2001 |
Systemic activity of the avermectins against the cat flea (Siphonaptera: Pulicidae).
Topics: Animals; Cats; Dogs; Insect Control; Insecticides; Ivermectin; Membranes, Artificial; Molecular Structure; Siphonaptera | 2001 |
Avermectin resistance in Cooperia pectinata in cattle in Argentina.
Topics: Animals; Anthelmintics; Argentina; Cattle; Cattle Diseases; Drug Resistance; Feces; Intestinal Diseases, Parasitic; Ivermectin; Parasite Egg Count; Trichostrongyloidea; Trichostrongyloidiasis | 2001 |
Avermectin resistance of the cattle tick Boophilus microplus in Brazil.
Topics: Animals; Brazil; Cattle; Cattle Diseases; Drug Resistance; Insecticides; Ivermectin; Tick Infestations; Ticks | 2001 |
[Selective cytostatic and cytotoxic effects of avermectins].
Topics: Animals; Antibiotics, Antineoplastic; Cell Death; Cell Differentiation; Cell Division; Ivermectin; Rats; Tumor Cells, Cultured | 2001 |
[Effect of avermectns on Ca(2+)-dependent chloride currents in plasmalemma of Chara corallina cells].
Topics: Calcium; Cell Membrane; Chloride Channels; Chlorides; Dose-Response Relationship, Drug; Electrophysiology; Eukaryota; Ivermectin; Patch-Clamp Techniques | 2001 |
Extraction and isolation of avermectins and milbemycins from liver samples using unmodified supercritical CO2 with in-line trapping on basic alumina.
Topics: Aluminum Oxide; Animals; Anti-Bacterial Agents; Carbon Dioxide; Cattle; Chromatography, High Pressure Liquid; Chromatography, Supercritical Fluid; Ivermectin; Liver; Macrolides; Reproducibility of Results; Sensitivity and Specificity; Sheep; Spectrometry, Fluorescence; Swine | 2001 |
Organization of biosynthetic gene cluster for avermectin in Streptomyces avermitilis: analysis of enzymatic domains in four polyketide synthases.
Topics: Amino Acid Sequence; Anthelmintics; Ivermectin; Molecular Sequence Data; Multienzyme Complexes; Multigene Family; Protein Structure, Tertiary; Sequence Analysis, DNA; Streptomyces | 2001 |
Anionic cyclization approach toward perhydrobenzofuranone: stereocontrolled synthesis of the hexahydrobenzofuran subunit of avermectin.
Topics: Anions; Anthelmintics; Benzofurans; Ivermectin; Molecular Structure; Spectrum Analysis | 2002 |
[Proliferation and morphological differentiation of neurblastoma cells in cultured under the effect of avermectins].
Topics: Animals; Cell Differentiation; Cell Division; Ivermectin; Mice; Neuroblastoma; Tumor Cells, Cultured | 2001 |
Resistance to macrocyclic lactones in nematodes of goats.
Topics: Animals; Anthelmintics; Anti-Bacterial Agents; Drug Resistance; Feces; Goat Diseases; Goats; Ivermectin; Macrolides; Parasitic Sensitivity Tests; Trichostrongyloidea; Trichostrongyloidiasis; Victoria | 2002 |
Short communication serum copper, zinc, and calcium concentrations in lice-infested sheep.
Topics: Animals; Calcium; Copper; Insecticides; Ivermectin; Lice Infestations; Phthiraptera; Sheep; Species Specificity; Spectrophotometry, Atomic; Zinc | 2002 |
Streptomyces avermitilis sp. nov., nom. rev., a taxonomic home for the avermectin-producing streptomycetes.
Topics: Anthelmintics; DNA, Bacterial; DNA, Ribosomal; Ivermectin; Molecular Sequence Data; Phenotype; Phylogeny; RNA, Bacterial; RNA, Ribosomal, 16S; Species Specificity; Streptomyces; Terminology as Topic | 2002 |
Streptomyces avermectinius sp. nov., an avermectin-producing strain.
Topics: Anthelmintics; DNA, Bacterial; DNA, Ribosomal; Ivermectin; Microscopy, Electron, Scanning; Molecular Sequence Data; Nucleic Acid Hybridization; Phenotype; Phylogeny; RNA, Bacterial; RNA, Ribosomal, 16S; Streptomyces | 2002 |
Toxicities of emamectin benzoate homologues and photodegradates to Lepidoptera.
Topics: Animals; Insecticides; Ivermectin; Lepidoptera; Photochemistry; Spodoptera | 2002 |
[Effect of gene disruption of aveD on avermectins production in Streptomyces avermitilis].
Topics: Bacterial Proteins; Gene Silencing; Ivermectin; Methyltransferases; Streptomyces | 2001 |
Cloning and analysis of a DNA fragment stimulating avermectin production in various Streptomyces avermitilis strains.
Topics: Bacterial Proteins; Cloning, Molecular; DNA, Bacterial; Gene Expression Regulation, Bacterial; Genomic Library; Ivermectin; Molecular Sequence Data; Mutation; Open Reading Frames; Pigments, Biological; Sequence Analysis, DNA; Streptomyces | 2003 |
Partial strategic tick control within a herd of European breed cattle in the state of Rio Grande do Sul, southern Brazil.
Topics: Animals; Brazil; Breeding; Cattle; Cattle Diseases; Europe; Insecticides; Ivermectin; Tick Control; Tick Infestations; Ticks | 2002 |
Engineering the aveC gene to enhance the ratio of doramectin to its CHC-B2 analogue produced in Streptomyces avermitilis.
Topics: Base Sequence; Chloride Channels; Cloning, Molecular; DNA Mutational Analysis; Gene Expression Profiling; Gene Expression Regulation, Bacterial; Genetic Enhancement; Genetic Variation; Genome, Bacterial; Ivermectin; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Engineering; Quality Control; Recombination, Genetic; Species Specificity; Streptomyces | 2003 |
[Comparative analysis of degradation of native avermectins and spinosyns by UV-HPLC].
Topics: Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Insecticides; Ivermectin; Kinetics; Macrolides; Spectrophotometry, Ultraviolet | 2002 |
Identification of a gene cluster encoding meilingmycin biosynthesis among multiple polyketide synthase contigs isolated from Streptomyces nanchangensis NS3226.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; Genes, Bacterial; Ivermectin; Macrolides; Molecular Sequence Data; Multienzyme Complexes; Mutation; Nucleic Acid Hybridization; Plasmids; Sequence Analysis, DNA; Sequence Homology; Streptomyces | 2003 |
Cytochrome p450 complement (CYPome) of the avermectin-producer Streptomyces avermitilis and comparison to that of Streptomyces coelicolor A3(2).
Topics: Chromosomes, Fungal; Complement System Proteins; Cytochrome P-450 Enzyme System; Genome, Fungal; Ivermectin; Phylogeny; Streptomyces | 2003 |
Direct production of ivermectin-like drugs after domain exchange in the avermectin polyketide synthase of Streptomyces avermitilis ATCC31272.
Topics: Blotting, Southern; Drug Design; Fermentation; Genes, Bacterial; Ivermectin; Multienzyme Complexes; Mutation; Protein Structure, Tertiary; Streptomyces | 2003 |
Selection at a gamma-aminobutyric acid receptor gene in Haemonchus contortus resistant to avermectins/milbemycins.
Topics: Animals; Anthelmintics; DNA, Helminth; Drug Resistance; Gene Frequency; Haemonchiasis; Haemonchus; Ivermectin; Macrolides; Polymorphism, Single-Stranded Conformational; Receptors, GABA; Selection, Genetic; Sheep; Sheep Diseases | 2003 |
Synthesis and biological activities of novel 4"-alkylidene avermectin derivatives.
Topics: Animals; Artemia; Caenorhabditis elegans; Growth Inhibitors; Indicators and Reagents; Ivermectin; Molecular Conformation | 2003 |
[The use of avermectins in two goats with demodicosis].
Topics: Administration, Oral; Administration, Topical; Animals; Goat Diseases; Goats; Insecticides; Ivermectin; Mite Infestations; Mites; Skin; Treatment Outcome | 2003 |
Ethanol evolution rate: a new parameter to determine the feeding rate for the production of avermectins by Streptomyces avermitilis.
Topics: Culture Media; Ethanol; Glucose; Ivermectin; Oxygen; Streptomyces | 2004 |
Genomic organization of an avermectin receptor subunit from Haemonchus contortus and expression of its putative promoter region in Caenorhabditis elegans.
Topics: 3' Untranslated Regions; 5' Flanking Region; 5' Untranslated Regions; Animals; Animals, Genetically Modified; Anthelmintics; Artificial Gene Fusion; Base Sequence; Caenorhabditis elegans; Chloride Channels; Cloning, Molecular; Codon; DNA, Helminth; Exons; Genes, Helminth; Genes, Reporter; Green Fluorescent Proteins; Haemonchus; Introns; Ivermectin; Luminescent Proteins; Molecular Sequence Data; Promoter Regions, Genetic; Protein Sorting Signals; TATA Box | 2004 |
Avermectins inhibit multidrug resistance of tumor cells.
Topics: Animals; Cell Division; Cell Line, Tumor; Cell Survival; Cyclosporine; Dose-Response Relationship, Drug; Drug Combinations; Drug Evaluation, Preclinical; Drug Resistance, Multiple; Drug Synergism; Fluoresceins; Fluorescence; Humans; Ivermectin; Leukemia P388; Male; Mice; Paclitaxel; Rhodamine 123; Russia; Vincristine | 2004 |
Synthesis and biological evaluation of novel 4"-alkoxy avermectin derivatives.
Topics: Animals; Caenorhabditis elegans; Crustacea; Drug Evaluation, Preclinical; Ivermectin | 2004 |
Antitumor effect of avermectins.
Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Ivermectin; Leukemia P388; Male; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Mice, Inbred DBA | 2004 |
Improvement of transformation and electroduction in avermectin high-producer, Streptomyces avermitilis.
Topics: Electroporation; Ivermectin; Protoplasts; Streptomyces; Transformation, Bacterial | 2004 |
[Antitumor effect of natural avermectins].
Topics: Administration, Oral; Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Injections, Intraperitoneal; Injections, Subcutaneous; Ivermectin; Leukemia P388; Male; Mice | 2004 |
Evaluation of selective toxicity of five pesticides against Plutella xylostella (Lep: Plutellidae) and their side-effects against Cotesia plutellae (Hym: Braconidae) and Oomyzus sokolowskii (Hym: Eulophidae).
Topics: Animals; Hymenoptera; Insecticides; Ivermectin; Larva; Methomyl; Moths; Nitriles; Pest Control, Biological; Phenylurea Compounds; Pupa; Pyrazoles; Pyrethrins; Pyridines | 2004 |
[Modification of antitumor effect of vincristine by natural avermectins].
Topics: Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Antiparasitic Agents; Dose-Response Relationship, Drug; Ivermectin; Mice; Mice, Inbred DBA; Neoplasm Transplantation; Neoplasms, Experimental; Vincristine | 2004 |
[Differential acute mortality among the allozyme genotypes of Oxya chinensis by pesticide avermectin].
Topics: Alleles; Animals; Genotype; Glucose-6-Phosphate Isomerase; Grasshoppers; Insecticides; Ivermectin; L-Lactate Dehydrogenase; Phosphoglucomutase | 2004 |
[Migrating subcutaneous myasis with systemic manifestations caused by gadfly larvae].
Topics: Adult; Animals; Anthelmintics; Antinematodal Agents; Female; Humans; Insect Bites and Stings; Insecta; Ivermectin; Larva Migrans; Skin Diseases; Syncope | 2004 |
Controlled release of avermectin from porous hollow silica nanoparticles.
Topics: Delayed-Action Preparations; Hydrogen-Ion Concentration; Ivermectin; Nanostructures; Pesticides; Silicon Dioxide; Temperature; Time Factors | 2005 |
[Effects of bkdAB interruption on avermectin biosynthesis].
Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Ivermectin; Recombinant Proteins; Streptomyces | 2004 |
Analysis of the strongylid nematodes (Nematoda: Strongylidae) community after deworming of brood horses in Ukraine.
Topics: Animals; Anthelmintics; Feces; Female; Gastrointestinal Diseases; Horse Diseases; Horses; Ivermectin; Parasite Egg Count; Strongylida; Strongylida Infections; Time Factors; Ukraine | 2005 |
Alternative production of avermectin components in Streptomyces avermitilis by gene replacement.
Topics: Anthelmintics; Bacterial Proteins; DNA Primers; Genetic Engineering; Hydro-Lyases; Ivermectin; Multigene Family; Plasmids; Polymerase Chain Reaction; Recombination, Genetic; Streptomyces; Transformation, Bacterial | 2005 |
Contractile activity and motility responses of the dog heartworm Dirofilaria immitis to classical anthelmintics and other compounds.
Topics: Animals; Anthelmintics; Dirofilaria immitis; Dirofilariasis; Dog Diseases; Dogs; Female; Ivermectin; Muscle Contraction | 2005 |
Degradation of abamectin and doramectin on sheep grazed pasture.
Topics: Animals; Biodegradation, Environmental; Feces; Ivermectin; Risk Assessment; Sheep; Soil Microbiology; Soil Pollutants; Weather | 2005 |
Biocatalytic conversion of avermectin to 4"-oxo-avermectin: characterization of biocatalytically active bacterial strains and of cytochrome p450 monooxygenase enzymes and their genes.
Topics: Amino Acid Motifs; Amino Acid Sequence; Bacterial Proteins; Cytochrome P-450 Enzyme System; Ivermectin; Kinetics; Molecular Sequence Data; Oxidation-Reduction; Recombinant Proteins; Sequence Alignment; Sequence Analysis, DNA; Stereoisomerism; Streptomyces | 2005 |
Biocatalytic conversion of avermectin to 4"-oxo-avermectin: heterologous expression of the ema1 cytochrome P450 monooxygenase.
Topics: Amino Acid Sequence; Cytochrome P-450 Enzyme System; Disaccharides; Ferredoxins; Gene Expression Regulation, Bacterial; Genetic Engineering; Industrial Microbiology; Ivermectin; Oxidation-Reduction; Oxidoreductases; Promoter Regions, Genetic; Pseudomonas putida; Sequence Alignment; Streptomyces; Transformation, Bacterial | 2005 |
Controlled release of avermectin from porous hollow silica nanoparticles: influence of shell thickness on loading efficiency, UV-shielding property and release.
Topics: Delayed-Action Preparations; Drug Carriers; Drug Stability; Insecticides; Ivermectin; Microscopy, Electron, Transmission; Molecular Structure; Nanostructures; Porosity; Silicon Dioxide; Ultraviolet Rays | 2006 |
No-discharge atmospheric pressure chemical ionization: evaluation and application to the analysis of animal drug residues in complex matrices.
Topics: Animals; Antiprotozoal Agents; Atmospheric Pressure; Cattle; Coloring Agents; Drug Residues; Fishes; Food Analysis; Indicators and Reagents; Ivermectin; Meat; Milk; Reference Standards; Rosaniline Dyes; Spectrometry, Mass, Electrospray Ionization; Veterinary Drugs | 2006 |
Identification of impurities in ivermectin bulk material by mass spectrometry and NMR.
Topics: Drug Contamination; Insecticides; Isomerism; Ivermectin; Magnetic Resonance Spectroscopy; Mass Spectrometry | 2006 |
Construction of ivermectin producer by domain swaps of avermectin polyketide synthase in Streptomyces avermitilis.
Topics: Genetic Engineering; Ivermectin; Molecular Structure; Mutation; Plasmids; Polyketide Synthases; Polymerase Chain Reaction; Streptomyces | 2006 |
Effects of mid-season avermectin treatments on pyrethroid resistance in horn fly (Diptera: Muscidae) populations at three locations in Louisiana.
Topics: Alleles; Animals; Biological Assay; Cattle; Dose-Response Relationship, Drug; Genotype; Geography; Inhibitory Concentration 50; Insecticide Resistance; Insecticides; Ivermectin; Louisiana; Muscidae; Mutation; Seasons; Time Factors; Treatment Outcome | 2006 |
Enhancement and selective production of oligomycin through inactivation of avermectin's starter unit in Streptomyces avermitilis.
Topics: Gene Expression Regulation, Bacterial; Genetic Engineering; Genetic Vectors; Industrial Microbiology; Ivermectin; Oligomycins; Polymerase Chain Reaction; Streptomyces | 2006 |
Catalytic domain of AfsKav modulates both secondary metabolism and morphologic differentiation in Streptomyces avermitilis ATCC 31272.
Topics: Bacterial Proteins; Catalytic Domain; Genetic Complementation Test; Ivermectin; Melanins; Mutation; Protein Serine-Threonine Kinases; Spores, Bacterial; Streptomyces | 2006 |
Determination of multiresidue of avermectins in bovine liver by an indirect competitive ELISA.
Topics: Animals; Binding, Competitive; Cattle; Drug Residues; Enzyme-Linked Immunosorbent Assay; Hydrogen-Ion Concentration; Insecticides; Ivermectin; Liver; Osmolar Concentration | 2006 |
A computer model to simulate control of parasitic gastroenteritis in sheep on UK farms.
Topics: Animals; Anthelmintics; Computer Simulation; Decision Support Techniques; Feces; Female; Gastroenteritis; Ivermectin; Larva; Macrolides; Models, Biological; Parasite Egg Count; Sheep; Sheep Diseases; Trichostrongyloidea; Trichostrongyloidiasis; United Kingdom | 2006 |
Avermectin-resistance in gastrointestinal nematodes of Boer goats and Dorper sheep in Switzerland.
Topics: Animal Husbandry; Animals; Antinematodal Agents; Drug Resistance; Feces; Female; Goat Diseases; Goats; Ivermectin; Levamisole; Male; Nematode Infections; Parasite Egg Count; Parasitic Sensitivity Tests; Sheep; Sheep Diseases; Surveys and Questionnaires; Switzerland; Treatment Outcome | 2007 |
Study of UV-shielding properties of novel porous hollow silica nanoparticle carriers for avermectin.
Topics: Drug Carriers; Hydrogen-Ion Concentration; Ivermectin; Nanoparticles; Particle Size; Pesticides; Silicon Dioxide; Temperature; Ultraviolet Rays | 2007 |
The in vitro characterization of the iterative avermectin glycosyltransferase AveBI reveals reaction reversibility and sugar nucleotide flexibility.
Topics: Catalysis; Chromatography, High Pressure Liquid; Enzyme Activation; Glycosyltransferases; Ivermectin; Molecular Conformation; Nucleotides; Sensitivity and Specificity; Stereoisomerism | 2006 |
Engineering of the spinosyn PKS: directing starter unit incorporation.
Topics: Amino Acid Sequence; Animals; Base Sequence; DNA; Erythromycin; Escherichia coli; Insecticides; Ivermectin; Macrolides; Models, Molecular; Polyketide Synthases; Protein Engineering; Saccharopolyspora; Streptomyces; Tetranychidae | 2006 |
Identification of the genes encoding for putative gamma aminobutyric acid (GABA) and glutamate-gated chloride channel (GluCl) alpha receptor subunits in sea lice (Lepeophtheirus salmonis).
Topics: Amino Acid Sequence; Animals; Chloride Channels; Copepoda; DNA Primers; Insecticides; Ion Channel Gating; Ivermectin; Lice Infestations; Molecular Sequence Data; Polymerase Chain Reaction; Receptors, GABA-A; RNA, Messenger; Salmo salar; Sequence Alignment; Sequence Homology, Amino Acid | 2007 |
The derivatisation of avermectins and milbemycins in milk: new insights and improvement of the procedure.
Topics: Acetic Anhydrides; Animals; Cattle; Ethylamines; Fluoroacetates; Food Analysis; Imidazoles; Ivermectin; Macrolides; Milk; Trifluoroacetic Acid | 2007 |
Effects of avermectin residues in cattle dung on yellow dung fly Scathophaga stercoraria (Diptera: Scathophagidae) populations in grazed pastures.
Topics: Animals; Cattle; Diptera; Insecticides; Ivermectin; Pesticide Residues; Population Density; Population Dynamics; Wings, Animal | 2007 |
[Cloning of bldAa and the effect on morphological differentiation and avermectins production in Streptomyces avermitilis NRRL8165].
Topics: Cloning, Molecular; Codon; Ivermectin; RNA, Bacterial; RNA, Transfer, Leu; Streptomyces | 2007 |
Adsorption of avermectin on porous hollow silica nanoparticles by supercritical technology.
Topics: Adsorption; Calcium Carbonate; Carbon Dioxide; Delayed-Action Preparations; Insecticides; Ivermectin; Microscopy, Electron, Transmission; Models, Chemical; Molecular Structure; Nanoparticles; Nanostructures; Nitrogen; Particle Size; Phase Transition; Porosity; Pressure; Silicon Dioxide; Solvents; Temperature; Time Factors | 2007 |
Biocatalytic conversion of avermectin to 4''-oxo-avermectin: improvement of cytochrome p450 monooxygenase specificity by directed evolution.
Topics: Biotransformation; Cytochrome P-450 Enzyme System; Directed Molecular Evolution; Disaccharides; Gene Library; Genes, Bacterial; Insecticides; Ivermectin; Molecular Sequence Data; Mutation; Oxidation-Reduction; Streptomyces; Substrate Specificity | 2007 |
Fast separation liquid chromatography-tandem mass spectrometry for the confirmation and quantitative analysis of avermectin residues in food.
Topics: Chromatography, High Pressure Liquid; Food Analysis; Ivermectin; Solid Phase Extraction; Tandem Mass Spectrometry | 2007 |
Insecticide susceptibility of surviving Cotesia plutellae (Hym: Braconidae) and Diaeretiella rapae (M'Intosh) (Hym: Aphidiidae) as affected by sublethal insecticide dosages on host insects.
Topics: Acetylcholinesterase; Animals; Aphids; Insecticide Resistance; Insecticides; Ivermectin; Moths; Organothiophosphorus Compounds; Wasps | 2007 |
Relationship between volatile odorous substances and production of avermectins by Streptomyces avermitilis.
Topics: Biotechnology; Fermentation; Gas Chromatography-Mass Spectrometry; Ivermectin; Kinetics; Naphthols; Odorants; Streptomyces; Volatilization | 2007 |
Avermectin transepithelial transport in MDR1- and MRP-transfected canine kidney monolayers.
Topics: Animals; Anthelmintics; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cell Line; Dogs; Ivermectin; Kidney; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins | 2008 |
Effects of avermectins on olfactory responses of Culicoides imicola (Diptera: Ceratopogonidae).
Topics: Animals; Bluetongue virus; Butanones; Ceratopogonidae; Insect Vectors; Insecticides; Ivermectin; Lactic Acid; Smell | 2007 |
[Effect of Avermectins on the secretion function of cultured granulosa cells from rat ovary in vitro.].
Topics: Animals; Cells, Cultured; Female; Granulosa Cells; Ivermectin; Rats | 2007 |
Comparative transcriptome analysis for avermectin overproduction via Streptomyces avermitilis microarray system.
Topics: Antiparasitic Agents; Bacterial Proteins; Gene Expression Profiling; Gene Expression Regulation, Bacterial; Genome, Bacterial; Ivermectin; Oligonucleotide Array Sequence Analysis; Polyketide Synthases; Streptomyces; Up-Regulation | 2007 |
Two threonine residues required for role of AfsKav in controlling morphogenesis and avermectin production in Streptomyces avermitilis.
Topics: Gene Expression Regulation, Bacterial; Ivermectin; Morphogenesis; Mutation; Protein Serine-Threonine Kinases; S-Adenosylmethionine; Streptomyces; Threonine | 2007 |
Anthelmintic macrolactams from Nonomuraea turkmeniaca MA7381.
Topics: Animals; Anthelmintics; Ivermectin; Lactams; Mice; Nematospiroides dubius; Strongylida Infections | 2008 |
Rearrangement of a cyclohexyl radical to a cyclopentylmethyl radical on the avermectin skeleton.
Topics: Cyclohexanes; Cyclopentanes; Ivermectin; Oxidation-Reduction | 2008 |
Ymf 1029A-E, preussomerin analogues from the fresh-water-derived fungus YMF 1.01029.
Topics: Animals; Antinematodal Agents; Epoxy Compounds; Fresh Water; Fungi; Heterocyclic Compounds, 4 or More Rings; Inhibitory Concentration 50; Ivermectin; Molecular Structure; Nematoda; Trees | 2008 |
Characterization of a negative regulator AveI for avermectin biosynthesis in Streptomyces avermitilis NRRL8165.
Topics: Anthraquinones; Bacterial Proteins; Gene Expression; Gene Expression Regulation, Bacterial; Ivermectin; Polyketide Synthases; Promoter Regions, Genetic; Repressor Proteins; Sequence Deletion; Streptomyces; Transcription Factors | 2008 |
Engineering of avermectin biosynthetic genes to improve production of ivermectin in Streptomyces avermitilis.
Topics: Amino Acid Sequence; Antiparasitic Agents; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Cloning, Molecular; Combinatorial Chemistry Techniques; Drug Design; Genetic Engineering; Ivermectin; Models, Chemical; Molecular Sequence Data; Multigene Family; Nucleotides; Streptomyces | 2008 |
Substituent effects on the rearrangements of cyclohexyl to cyclopentyl radicals involving avermectin-related radicals.
Topics: Cyclohexanes; Cyclopentanes; Free Radicals; Ivermectin; Models, Molecular; Thermodynamics | 2008 |
Development of an analytical method to determine avermectins in water, sediments and soils using liquid chromatography-tandem mass spectrometry.
Topics: Calibration; Chromatography, Liquid; Geologic Sediments; Ivermectin; Pressure; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Soil Pollutants; Solid Phase Extraction; Tandem Mass Spectrometry; Water Pollutants, Chemical | 2008 |
Large volume injection for the direct analysis of ionophores and avermectins in surface water by liquid chromatography-electrospray ionization tandem mass spectrometry.
Topics: Anti-Bacterial Agents; Antiparasitic Agents; Chromatography, Liquid; Ionophores; Ivermectin; Reproducibility of Results; Sensitivity and Specificity; Solid Phase Extraction; Spectrometry, Mass, Electrospray Ionization; Water; Water Pollutants, Chemical | 2009 |
Ivermectin-derived leishmanicidal compounds.
Topics: Animals; Benzofurans; Disaccharides; Ivermectin; Leishmania mexicana; Macrophages; Mice; Parasitic Sensitivity Tests; Structure-Activity Relationship; Trypanocidal Agents | 2009 |
Characterization of a regulatory gene, aveR, for the biosynthesis of avermectin in Streptomyces avermitilis.
Topics: Bacterial Proteins; Gene Deletion; Gene Expression Regulation, Bacterial; Genetic Complementation Test; Ivermectin; Streptomyces; Transcription Factors | 2009 |
[Effect on production of avermectins of spore pigment biosynthesis in Streptomyces avermitilis NRRL8165].
Topics: Bacterial Proteins; Cloning, Molecular; Ivermectin; Mutation; Peptides; Spores, Bacterial; Streptomyces | 2008 |
Rapid method for multi-residue determination of avermectins in bovine liver using high-performance liquid chromatography with fluorescence detection.
Topics: Animals; Antiparasitic Agents; Cattle; Chromatography, High Pressure Liquid; Environmental Monitoring; Ivermectin; Liver; Spectrometry, Fluorescence | 2009 |
Functional expression of SAV3818, a putative TetR-family transcriptional regulatory gene from Streptomyces avermitilis, stimulates antibiotic production in Streptomyces species.
Topics: Anthraquinones; Anti-Bacterial Agents; Bacterial Proteins; Gene Expression Profiling; Gene Expression Regulation, Bacterial; Genes, Bacterial; Genes, Regulator; Ivermectin; Streptomyces | 2009 |
Influence of posttreatment temperature on the toxicity of insecticides against Diaphorina citri (Hemiptera: Psyllidae).
Topics: Anabasine; Animals; Carbamates; Hemiptera; Insecticides; Ivermectin; Organophosphates; Pyrethrins; Temperature | 2009 |
Avermectin exerts anti-inflammatory effect by downregulating the nuclear transcription factor kappa-B and mitogen-activated protein kinase activation pathway.
Topics: Animals; Anti-Inflammatory Agents; Cells, Cultured; Cytokines; Dose-Response Relationship, Drug; Down-Regulation; Excitatory Amino Acid Agonists; Inflammation; Ivermectin; Lipopolysaccharides; Macrophages; Mice; Mitogen-Activated Protein Kinases; NF-kappa B; Signal Transduction | 2009 |
Preparation and characterization of monoclonal antibodies against avermectin.
Topics: Animals; Anthelmintics; Antibodies, Monoclonal; Antibody Specificity; Cross Reactions; Enzyme-Linked Immunosorbent Assay; Female; Ivermectin; Mice; Mice, Inbred BALB C | 2009 |
Field-scale dispersal of Aphodius dung beetles (Coleoptera: Scarabaeidae) in response to avermectin treatments on pastured cattle.
Topics: Animals; Anthelmintics; Cattle; Cattle Diseases; Coleoptera; Feces; Ivermectin; Linear Models; Population Density; Scotland | 2010 |
[Determination of avermectin residues in tea by ultra-performance liquid chromatography-electrospray tandem mass spectrometry].
Topics: Chromatography, High Pressure Liquid; Disaccharides; Drug Residues; Food Contamination; Humans; Ivermectin; Tandem Mass Spectrometry; Tea | 2009 |
Avermectin intoxication with coma, myoclonus, and polyneuropathy.
Topics: Activities of Daily Living; Aged; Coma; Humans; Insecticides; Ivermectin; Male; Myoclonus; Peripheral Nervous System; Poisoning; Polyneuropathies; Suicide, Attempted | 2009 |
Simultaneous determination of avermectins in bovine tissues by LC-MS/MS.
Topics: Animals; Calibration; Cattle; Chromatography, Gel; Ivermectin; Limit of Detection; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2009 |
Identification of avermectin-high-producing strains by high-throughput screening methods.
Topics: Chromatography, High Pressure Liquid; Fermentation; High-Throughput Screening Assays; Industrial Microbiology; Ivermectin; Reproducibility of Results; Streptomyces; Ultraviolet Rays | 2010 |
The pathway-specific regulator AveR from Streptomyces avermitilis positively regulates avermectin production while it negatively affects oligomycin biosynthesis.
Topics: Chromatin Immunoprecipitation; Gene Deletion; Gene Expression Regulation, Bacterial; Helix-Turn-Helix Motifs; Ivermectin; Multigene Family; Oligomycins; Promoter Regions, Genetic; Repressor Proteins; Streptomyces; Trans-Activators | 2010 |
Synthesis of natural products containing spiroketals via intramolecular hydrogen abstraction.
Topics: Anthelmintics; Anti-Bacterial Agents; Antineoplastic Agents; Benzofurans; Biological Products; Bridged-Ring Compounds; Ciguatoxins; Cyclization; Ethers; Ethers, Cyclic; Furans; Hydrogen; Ivermectin; Marine Toxins; Molecular Structure; Oxazoles; Oxidation-Reduction; Phenazines; Phosphoprotein Phosphatases; Pyrans; Spiro Compounds | 2010 |
Construction of a doramectin producer mutant from an avermectin-overproducing industrial strain of Streptomyces avermitilis.
Topics: Anthelmintics; Fermentation; Gene Deletion; Genetic Engineering; Industrial Microbiology; Insecticides; Ivermectin; Multienzyme Complexes; Multigene Family; Mutation; Oxidoreductases Acting on CH-CH Group Donors; Polyketide Synthases; Streptomyces | 2009 |
[Clinical analysis of acute Avermectins poisoning].
Topics: Acute Disease; Adolescent; Adult; Aged; Child; Female; Follow-Up Studies; Humans; Ivermectin; Male; Middle Aged; Retrospective Studies; Young Adult | 2009 |
Effects of insecticides on the fluidity of mitochondrial membranes of the diamondback moth, Plutella xylostella, resistant and susceptible to avermectin.
Topics: Animals; Drug Resistance; Insecticides; Ivermectin; Larva; Membrane Fluidity; Mitochondrial Membranes; Moths | 2008 |
Overexpression of ribosome recycling factor causes increased production of avermectin in Streptomyces avermitilis strains.
Topics: Bacterial Proteins; Gene Expression Regulation, Bacterial; Ivermectin; Ribosomal Proteins; Streptomyces | 2010 |
[Analysis of methanogenic community of anaerobic granular sludge in a full-scale UASB treating avermectin wastewater].
Topics: Anaerobiosis; Bioreactors; Ivermectin; Methanobacteriales; Methanomicrobiaceae; Methanosarcina; Population Dynamics; Sewage; Waste Disposal, Fluid | 2010 |
[Avermectin poisoning in a child].
Topics: Child, Preschool; Female; Humans; Insecticides; Ivermectin | 2010 |
Alterations in the fat body and midgut of Culex quinquefasciatus larvae following exposure to different insecticides.
Topics: Animals; Culex; Fat Body; Histocytochemistry; Insecticides; Intestines; Ivermectin; Larva; Microscopy; Microscopy, Electron, Scanning; Pyrethrins | 2010 |
Assessing the potential of an induced-mutation strategy for avermectin overproducers.
Topics: Biotechnology; Culture Media; Ivermectin; Methylnitronitrosoguanidine; Mutagenesis; Mutation; Phenotype; Streptomyces; Ultraviolet Rays; Weightlessness | 2010 |
Characterisation of milbemycin-, avermectin-, imidazothiazole- and benzimidazole-resistant Teladorsagia circumcincta from a sheep flock.
Topics: Animals; Anthelmintics; Benzimidazoles; Drug Resistance, Multiple; Feces; Ivermectin; Macrolides; Parasite Egg Count; Sheep; Sheep Diseases; Thiadiazoles; Trichostrongyloidea; Trichostrongyloidiasis | 2010 |
Reverse biological engineering of hrdB to enhance the production of avermectins in an industrial strain of Streptomyces avermitilis.
Topics: Bacterial Proteins; Base Sequence; Bioengineering; DNA-Binding Proteins; DNA-Directed RNA Polymerases; Gene Expression Regulation, Bacterial; Gene Library; Genetic Engineering; Ivermectin; Molecular Sequence Data; Mutation; Oligonucleotide Array Sequence Analysis; Promoter Regions, Genetic; Sequence Homology, Nucleic Acid; Sigma Factor; Streptomyces; Transcription, Genetic | 2010 |
Determination of anthelmintic drug residues in milk using ultra high performance liquid chromatography-tandem mass spectrometry with rapid polarity switching.
Topics: Animals; Anthelmintics; Benzimidazoles; Chromatography, High Pressure Liquid; Drug Residues; Ivermectin; Milk; Models, Statistical; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry | 2010 |
Potential avermectin resistance in a cattle herd.
Topics: Animals; Anthelmintics; Cattle; Cattle Diseases; Drug Resistance; Feces; Ivermectin; Trichostrongylus | 2010 |
[Determination of avermectin and ivermectin in swine muscular tissues using high performance liquid chromatography-tandem mass spectrometry].
Topics: Animals; Chromatography, High Pressure Liquid; Food Contamination; Ivermectin; Meat; Muscle, Skeletal; Swine; Tandem Mass Spectrometry | 2010 |
Enhancement of avermectin and ivermectin production by overexpression of the maltose ATP-binding cassette transporter in Streptomyces avermitilis.
Topics: ATP-Binding Cassette Transporters; Carbon; Culture Media; Gene Deletion; Gene Expression Regulation, Bacterial; Genes, Bacterial; Ivermectin; Maltose; Oligomycins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Starch; Streptomyces | 2010 |
Effects of age and immune suppression of sheep on fecundity, hatching and larval feeding of different strains of Haemonchus contortus.
Topics: Abomasum; Age Factors; Animals; Anthelmintics; Anti-Inflammatory Agents; Benzimidazoles; Feces; Feeding Behavior; Female; Fertility; Haemonchiasis; Haemonchus; Immunosuppression Therapy; Ivermectin; Larva; Male; Methylprednisolone; Methylprednisolone Acetate; Reproduction; Sheep; Sheep Diseases; Sheep, Domestic | 2011 |
Development of a molecularly imprinted polymer for the analysis of avermectin.
Topics: Chemistry Techniques, Analytical; Chromatography, High Pressure Liquid; Insecticides; Ivermectin; Molecular Imprinting; Molecular Structure | 2010 |
Understanding the impact of P-glycoprotein mutation on canine health.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Dirofilariasis; Dog Diseases; Dogs; Filaricides; Ivermectin; Mutation | 2011 |
Novel photodegradable insecticide W/TiO(2)/Avermectin nanocomposites obtained by polyelectrolytes assembly.
Topics: Alginates; Animals; Biological Assay; Catalysis; Chitosan; Coleoptera; Crystallization; Electrolytes; Electrophoresis; Glucuronic Acid; Hexuronic Acids; Insecticides; Ivermectin; Nanocomposites; Particle Size; Photolysis; Solutions; Surface Properties; Titanium; Toxicity Tests; Tungsten; Ultraviolet Rays | 2011 |
Insecticide resistance of the oriental fruit fly, Bactrocera dorsalis (Hendel) (Diptera: Tephritidae), in mainland China.
Topics: Animals; China; Genotype; Insect Control; Insecticide Resistance; Insecticides; Ivermectin; Pyrethrins; Tephritidae; Trichlorfon | 2011 |
Pivalic acid acts as a starter unit in a fatty acid and antibiotic biosynthetic pathway in Alicyclobacillus, Rhodococcus and Streptomyces.
Topics: Alicyclobacillus; Anti-Bacterial Agents; Butyrates; Fatty Acids; Ivermectin; Pentanoic Acids; Rhodococcus; Streptomyces | 2011 |
Production of doramectin by rational engineering of the avermectin biosynthetic pathway.
Topics: Anthelmintics; Biosynthetic Pathways; Chromatography, High Pressure Liquid; Gene Expression Regulation, Bacterial; Genetic Engineering; Ivermectin; Recombinant Proteins; Streptomyces | 2011 |
Multi-residue method for the confirmation of four avermectin residues in food products of animal origin by ultra-performance liquid chromatography-tandem mass spectrometry.
Topics: Animals; Antiparasitic Agents; Calibration; China; Chromatography, High Pressure Liquid; Drug Residues; Food Inspection; Humans; Ivermectin; Limit of Detection; Liver; Meat; Milk; Reproducibility of Results; Seafood; Spectrometry, Mass, Electrospray Ionization; Sus scrofa; Tandem Mass Spectrometry; Teratogens; Veterinary Drugs | 2011 |
The autoregulator receptor homologue AvaR3 plays a regulatory role in antibiotic production, mycelial aggregation and colony development of Streptomyces avermitilis.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Biosynthetic Pathways; Culture Media; Filipin; Gene Expression Profiling; Gene Expression Regulation, Bacterial; Gene Knockout Techniques; Genes, Bacterial; Ivermectin; Multigene Family; Mutagenesis, Insertional; Streptomyces | 2011 |
[Determination of avermectin, diclazuril, toltrazuril and metabolite residues in pork by high performance liquid chromatography-tandem mass spectrometry].
Topics: Animals; Chromatography, High Pressure Liquid; Drug Residues; Food Contamination; Ivermectin; Meat; Nitriles; Swine; Tandem Mass Spectrometry; Triazines | 2011 |
Inactivation of the extracytoplasmic function sigma factor Sig6 stimulates avermectin production in Streptomyces avermitilis.
Topics: Bacterial Proteins; Gene Deletion; Gene Expression Regulation, Bacterial; Gene Silencing; Ivermectin; Mutation; Reverse Transcriptase Polymerase Chain Reaction; Sigma Factor; Signal Transduction; Streptomyces; Transcription Factors | 2011 |
Yeast screening from avermectins wastewater and investigation on the ability of its fermentation.
Topics: Bioreactors; Candida tropicalis; Carbohydrates; DNA, Ribosomal; Fermentation; Hydrogen-Ion Concentration; Ivermectin; Nitrogen; Pharmaceutical Preparations; Powders; Saccharomyces cerevisiae; Streptomyces; Temperature; Waste Disposal, Fluid; Water Pollutants, Chemical; Water Purification | 2011 |
Overexpression of the ABC transporter AvtAB increases avermectin production in Streptomyces avermitilis.
Topics: ATP-Binding Cassette Transporters; Bacterial Proteins; Biological Transport; Gene Dosage; Gene Expression; Gene Expression Regulation, Bacterial; Genetic Engineering; Ivermectin; Streptomyces | 2011 |
[Analysis of methanogenic community of anaerobic granular sludge based on mcrA gene].
Topics: Anaerobiosis; Bioreactors; Genes, Archaeal; Ivermectin; Methanomicrobiaceae; Methanosarcina; Oxidoreductases; Population Dynamics; RNA, Ribosomal, 16S; Sewage; Waste Disposal, Fluid | 2011 |
Expression of CYP107Z13 in Streptomyces lividans TK54 catalyzes the oxidation of avermectin to 4″-oxo-avermectin.
Topics: Chromatography, High Pressure Liquid; Cloning, Molecular; Culture Media; Cytochrome P-450 Enzyme System; Gene Expression; Ivermectin; Metabolic Engineering; Metabolome; Oxidation-Reduction; Promoter Regions, Genetic; Streptomyces lividans | 2012 |
Avenolide, a Streptomyces hormone controlling antibiotic production in Streptomyces avermitilis.
Topics: Anthelmintics; Culture Media; Hormones; Ivermectin; Ligands; Mass Spectrometry; Nuclear Magnetic Resonance, Biomolecular; Solvents; Streptomyces | 2011 |
Magnetic field is the dominant factor to induce the response of Streptomyces avermitilis in altered gravity simulated by diamagnetic levitation.
Topics: Ivermectin; Magnetics; Microscopy, Electron; Models, Theoretical; Streptomyces; Weightlessness | 2011 |
[Resistance realized heritability and risk assessment of Panonychus citri to avermectin and fenpropathrin].
Topics: Acaricides; Animals; Citrus; Drug Resistance; Ivermectin; Mites; Pyrethrins | 2011 |
Development and validation of a multiclass method for the determination of veterinary drug residues in chicken by ultra high performance liquid chromatography-tandem mass spectrometry.
Topics: Animals; Anthelmintics; Anti-Bacterial Agents; Chickens; Chromatography, High Pressure Liquid; Drug Residues; Ethylenediamines; Ivermectin; Limit of Detection; Macrolides; Muscle, Skeletal; Poultry Products; Quinolones; Reproducibility of Results; Sulfonamides; Tandem Mass Spectrometry; Veterinary Drugs | 2012 |
Species displacements are common to two invasive species of leafminer fly in China, Japan, and the United States.
Topics: Animals; China; Competitive Behavior; Diptera; Fabaceae; Female; Insecticide Resistance; Insecticides; Introduced Species; Ivermectin; Japan; Larva; Male; Species Specificity; Triazines; United States | 2011 |
Molecular characterization of the sigma class gutathione S-transferase from Chilo suppressalis and expression analysis upon bacterial and insecticidal challenge.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cloning, Molecular; DNA, Complementary; Escherichia coli; Gene Expression Profiling; Gene Expression Regulation, Enzymologic; Glutathione Transferase; Insect Proteins; Insecticides; Ivermectin; Larva; Micrococcus luteus; Molecular Sequence Data; Moths; ortho-Aminobenzoates; Phylogeny; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Sequence Alignment | 2011 |
Deletion of ku homologs increases gene targeting frequency in Streptomyces avermitilis.
Topics: Antiparasitic Agents; Bacterial Proteins; DNA End-Joining Repair; DNA-Binding Proteins; Gene Deletion; Gene Targeting; Industrial Microbiology; Ivermectin; Streptomyces | 2012 |
Evaluation of neonicotinoid, organophosphate and avermectin trunk injections for the management of avocado thrips in California avocado groves.
Topics: Animals; Guanidines; Imidazoles; Insect Control; Insecticides; Ivermectin; Neonicotinoids; Nitro Compounds; Organophosphates; Persea; Plant Diseases; Plant Stems; Thysanoptera | 2012 |
Lethal and sublethal effects of avermectin/milbemycin parasiticides on the African malaria vector, Anopheles arabiensis.
Topics: Animals; Anopheles; Cattle; Insect Vectors; Insecticides; Ivermectin; Lethal Dose 50; Macrolides; Mosquito Control | 2012 |
The efficacy of four avermectins on the synanthropic mite Lepidoglyphus destructor under laboratory conditions.
Topics: Acaricides; Animals; Dose-Response Relationship, Drug; Ivermectin; Mites; Reproduction | 2012 |
Determination of 17 macrolide antibiotics and avermectins residues in meat with accelerated solvent extraction by liquid chromatography-tandem mass spectrometry.
Topics: Animals; Anti-Bacterial Agents; Cattle; Chromatography, Liquid; Drug Residues; Ivermectin; Liquid-Liquid Extraction; Macrolides; Meat; Pressure; Swine; Tandem Mass Spectrometry; Temperature | 2012 |
Insecticide-mediated apparent displacement between two invasive species of leafminer fly.
Topics: Agriculture; Animals; Diptera; Ecosystem; Insecticides; Ivermectin; Larva; Triazines | 2012 |
Differential regulation of antibiotic biosynthesis by DraR-K, a novel two-component system in Streptomyces coelicolor.
Topics: Actins; Anthraquinones; Anti-Bacterial Agents; Bacterial Proteins; Base Sequence; Binding Sites; DNA-Binding Proteins; Feedback, Physiological; Gene Expression Regulation, Bacterial; Gene Order; Helminth Proteins; Ivermectin; Molecular Sequence Data; Mutation; Oligomycins; Phenotype; Promoter Regions, Genetic; Protein Binding; Signal Transduction; Streptomyces coelicolor | 2012 |
A monoclonal antibody-based ELISA for multiresidue determination of avermectins in milk.
Topics: Animals; Antibodies, Monoclonal; Antigens; Cattle; Enzyme-Linked Immunosorbent Assay; Female; Hydrogen-Ion Concentration; Ivermectin; Methanol; Mice; Mice, Inbred BALB C; Milk; Temperature | 2012 |
[Hemoperfusion in the treatment of an acute avermectin poisoning patient with liver cirrhosis].
Topics: Hemoperfusion; Humans; Ivermectin; Liver Cirrhosis; Male; Middle Aged | 2012 |
Differential susceptibilities of Brontispa longissima (Coleoptera: Hispidae) to insecticides in Southeast Asia.
Topics: Animals; Asia, Southeastern; Coleoptera; Dose-Response Relationship, Drug; Insecticide Resistance; Insecticides; Ivermectin; Neonicotinoids; Pyrethrins; Pyridines | 2012 |
Utilization of environmental waste cyanobacteria as a pesticide carrier: studies on controlled release and photostability of avermectin.
Topics: Cyanobacteria; Ivermectin; Microscopy, Electron, Scanning; Pesticides; Photoelectron Spectroscopy; Spectrophotometry, Infrared | 2013 |
Development of an extraction method for the determination of avermectins in soil using supercritical CO2 modified with ethanol and liquid chromatography-tandem mass spectrometry.
Topics: Carbon Dioxide; Chromatography, Liquid; Ethanol; Ivermectin; Soil; Tandem Mass Spectrometry | 2013 |
Anthelmintic avermectins kill Mycobacterium tuberculosis, including multidrug-resistant clinical strains.
Topics: Anthelmintics; Anti-Bacterial Agents; Drug Resistance, Multiple, Bacterial; Humans; Ivermectin; Macrolides; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Tuberculosis; Tuberculosis, Multidrug-Resistant | 2013 |
Direct proteomic mapping of Streptomyces avermitilis wild and industrial strain and insights into avermectin production.
Topics: Culture Media; Fermentation; Gene Expression Regulation, Bacterial; Ivermectin; Proteome; Proteomics; Streptomyces | 2013 |
Spiroketal formation and modification in avermectin biosynthesis involves a dual activity of AveC.
Topics: Biological Products; Crystallography, X-Ray; Ivermectin; Models, Molecular; Molecular Structure; Mutation; Spiro Compounds | 2013 |
Anthelmintic resistance in Northern Ireland (I): prevalence of resistance in ovine gastrointestinal nematodes, as determined through faecal egg count reduction testing.
Topics: Aminoacetonitrile; Animals; Anthelmintics; Antinematodal Agents; Benzimidazoles; Drug Resistance; Feces; Gastrointestinal Diseases; Ivermectin; Levamisole; Macrolides; Northern Ireland; Parasite Egg Count; Prevalence; Sheep; Sheep Diseases; Sheep, Domestic; Treatment Outcome; Trichostrongyloidea; Trichostrongyloidiasis | 2013 |
Application of hollow-fiber-assisted liquid-phase microextraction to identify avermectins in stream water using MS/MS.
Topics: Anthelmintics; Ivermectin; Limit of Detection; Liquid Phase Microextraction; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2013 |
Avermectin induces P-glycoprotein expression in S2 cells via the calcium/calmodulin/NF-κB pathway.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; Calcium; Calcium Channels; Calmodulin; Cell Line; Chloride Channels; Chlorides; Drosophila melanogaster; Drug Resistance; Humans; Intracellular Space; Ivermectin; NF-kappa B; Signal Transduction; Up-Regulation | 2013 |
Overexpression of metK shows different effects on avermectin production in various Streptomyces avermitilis strains.
Topics: Cloning, Molecular; Gene Expression; Genetic Vectors; Ivermectin; Metabolic Engineering; Methionine Adenosyltransferase; Plasmids; Streptomyces | 2013 |
Engineered Streptomyces avermitilis host for heterologous expression of biosynthetic gene cluster for secondary metabolites.
Topics: Cloning, Molecular; Gene Expression Regulation, Bacterial; Genetic Enhancement; Ivermectin; Multigene Family; Protein Engineering; Secondary Metabolism; Species Specificity; Streptomyces; Synthetic Biology | 2013 |
Characterization of SAV7471, a TetR-family transcriptional regulator involved in the regulation of coenzyme A metabolism in Streptomyces avermitilis.
Topics: Bacterial Proteins; Coenzyme A; Gene Deletion; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Ivermectin; Streptomyces; Trans-Activators | 2013 |
Antioxidant response and histopathological changes in brain tissue of pigeon exposed to avermectin.
Topics: Animals; Antioxidants; Brain; Columbidae; Dose-Response Relationship, Drug; Glutathione Peroxidase; Insecticides; Ivermectin; Oxidative Stress; Protein Carbonylation; Superoxide Dismutase | 2013 |
A novel TetR family transcriptional regulator, SAV576, negatively controls avermectin biosynthesis in Streptomyces avermitilis.
Topics: Bacterial Proteins; Base Sequence; Binding Sites; Chromosome Mapping; Chromosomes, Bacterial; DNA, Intergenic; Gene Deletion; Gene Expression Profiling; Gene Expression Regulation, Bacterial; Gene Order; Ivermectin; Molecular Sequence Data; Mutation; Promoter Regions, Genetic; Protein Binding; Streptomyces; Trans-Activators; Transcription, Genetic | 2013 |
Avermectin induced inflammation damage in king pigeon brain.
Topics: Animals; Antiparasitic Agents; Biomarkers; Brain; Columbidae; Inflammation; Ivermectin; NF-kappa B; Nitric Oxide Synthase Type II; RNA, Messenger | 2013 |
Avermectin induced liver injury in pigeon: mechanisms of apoptosis and oxidative stress.
Topics: Animals; Anti-Bacterial Agents; Antioxidants; Apoptosis; Caspase 3; Caspase 8; Columbidae; DNA Damage; Fas Ligand Protein; Glutathione Peroxidase; Ivermectin; Liver; Malondialdehyde; Mitochondria, Liver; Oxidative Stress; Protein Carbonylation; Superoxide Dismutase | 2013 |
The efficacy of avermectins (ivermectin, doramectin and abamectin) as treatments for infestation with the tick Haemaphysalis longicornis on rabbits in Korea.
Topics: Animals; Body Weight; Female; Insecticides; Ivermectin; Molting; Nymph; Ovary; Rabbits; Random Allocation; Republic of Korea; Tick Infestations; Ticks | 2013 |
Engineering of the TetR family transcriptional regulator SAV151 and its target genes increases avermectin production in Streptomyces avermitilis.
Topics: Antiparasitic Agents; Chromatin Immunoprecipitation; DNA, Bacterial; Electrophoretic Mobility Shift Assay; Gene Deletion; Gene Expression; Gene Expression Profiling; Gene Expression Regulation, Bacterial; Genetic Complementation Test; Ivermectin; Metabolic Engineering; Promoter Regions, Genetic; Protein Binding; Real-Time Polymerase Chain Reaction; Streptomyces; Transcription Factors | 2014 |
Nystagmus following acute avermectins poisoning.
Topics: China; Humans; Ivermectin; Male; Middle Aged; Nystagmus, Pathologic | 2016 |
Inhibition of P-glycoprotein in the blood-brain barrier alters avermectin neurotoxicity and swimming performance in rainbow trout.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Behavior, Animal; Blood-Brain Barrier; Central Nervous System; Hepatocytes; Ivermectin; Motor Activity; Oncorhynchus mykiss; Water Pollutants, Chemical | 2014 |
Characterization of AvaR1, an autoregulator receptor that negatively controls avermectins production in a high avermectin-producing strain.
Topics: Bacterial Proteins; Electrophoretic Mobility Shift Assay; Enzyme Activators; Gene Deletion; Gene Expression Profiling; Gene Expression Regulation, Bacterial; Ivermectin; Real-Time Polymerase Chain Reaction; Repressor Proteins; Streptomyces; Transcriptional Activation | 2014 |
Effects of avermectin on immune function and oxidative stress in the pigeon spleen.
Topics: Animals; Columbidae; Dose-Response Relationship, Drug; Environmental Pollutants; Immune System; Interferon-alpha; Interleukin-4; Ivermectin; Oxidative Stress; RNA, Messenger; Spleen; Tumor Necrosis Factor-alpha | 2014 |
Combined effects of temperature and avermectins on life history and stress response of the western flower thrips, Frankliniella occidentalis.
Topics: Animals; Female; Gene Expression Regulation; Insect Proteins; Ivermectin; Male; Pesticides; Reproduction; Temperature; Thysanoptera | 2014 |
Effect of stereochemistry of avermectin-like 6,6-spiroketals on biological activities and endogenous biotransformations in Streptomyces avermectinius.
Topics: Biotransformation; Furans; Ivermectin; Spiro Compounds; Stereoisomerism; Streptomyces | 2014 |
Measuring the effect of avermectins and milbemycins on somatic muscle contraction of adult Haemonchus contortus and on motility of Ostertagia circumcincta in vitro.
Topics: Animals; Antiparasitic Agents; Female; Haemonchus; Ivermectin; Macrolides; Muscle Contraction; Muscles; Ostertagia | 2014 |
Efficacy evaluation of fungus Syncephalastrum racemosum and nematicide avermectin against the root-knot nematode Meloidogyne incognita on cucumber.
Topics: Animals; Antinematodal Agents; Cucumis sativus; Ivermectin; Mucorales; Pest Control, Biological; Plant Diseases; Tylenchoidea | 2014 |
The effects of avermectin on amino acid neurotransmitters and their receptors in the pigeon brain.
Topics: Amino Acids; Animals; Brain; Columbidae; Insecticides; Ivermectin; Neurotransmitter Agents; Receptors, Neurotransmitter; RNA, Messenger | 2014 |
An extracytoplasmic function sigma factor, σ(25), differentially regulates avermectin and oligomycin biosynthesis in Streptomyces avermitilis.
Topics: Anti-Bacterial Agents; Binding Sites; DNA Footprinting; Gene Deletion; Gene Expression; Gene Expression Regulation, Bacterial; Genetic Complementation Test; Ivermectin; Oligomycins; Promoter Regions, Genetic; Sigma Factor; Streptomyces; Transcription, Genetic | 2014 |
Global DNA hypomethylation: a potential mechanism in King pigeon nerve tissue damage induced by avermectin.
Topics: Animals; Brain; Columbidae; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA-Binding Proteins; Dose-Response Relationship, Drug; Down-Regulation; Female; Insecticides; Ivermectin; Male; Random Allocation; Real-Time Polymerase Chain Reaction; RNA, Messenger | 2014 |
[Experimental study on adsorption effect of activated carbon to abamectin].
Topics: Adsorption; Charcoal; Ivermectin | 2014 |
Exploring the electron transfer pathway in the oxidation of avermectin by CYP107Z13 in Streptomyces ahygroscopicus ZB01.
Topics: Amino Acid Sequence; Biocatalysis; Cloning, Molecular; Cytochrome P-450 Enzyme System; Electron Transport; Ferredoxin-NADP Reductase; Ferredoxins; Ivermectin; Molecular Sequence Data; Mutation; NAD; Sequence Analysis; Streptomyces | 2014 |
Two adjacent and similar TetR family transcriptional regulator genes, SAV577 and SAV576, co-regulate avermectin production in Streptomyces avermitilis.
Topics: Amino Acid Sequence; Bacterial Proteins; Gene Expression Regulation, Bacterial; Genes, Bacterial; Genes, Regulator; Ivermectin; Molecular Sequence Data; Mutation; Streptomyces; Transcription, Genetic | 2014 |
Stereodivergent approach to the avermectins based on "super silyl" directed aldol reactions.
Topics: Aldehydes; Ivermectin; Molecular Structure; Stereoisomerism; Trimethylsilyl Compounds | 2014 |
[Study on the inclusion compound of avermectin by infrared spectroscopy].
Topics: beta-Cyclodextrins; Ivermectin; Spectrophotometry, Infrared | 2014 |
Reversal of meticillin resistance in Staphylococcus aureus by the anthelmintic avermectin.
Topics: Anthelmintics; Anti-Bacterial Agents; Drug Synergism; Humans; Ivermectin; Methicillin Resistance; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests | 2014 |
Fifteen years later, anthelmintic resistances have dramatically spread over goat farms in Guadeloupe.
Topics: Animals; Anthelmintics; Benzimidazoles; Drug Resistance; Feces; Goat Diseases; Goats; Guadeloupe; Haemonchiasis; Haemonchus; Ivermectin; Levamisole; Macrolides; Parasite Egg Count; Surveys and Questionnaires; Trichostrongylosis; Trichostrongylus | 2014 |
Effects of avermectin on microsomal cytochrome P450 enzymes in the liver and kidneys of pigeons.
Topics: Animals; Anthelmintics; Columbidae; Cytochrome P-450 Enzyme System; Environmental Pollutants; Gene Expression Regulation, Enzymologic; Ivermectin; Kidney; Liver; Microsomes; Time Factors | 2014 |
The change in heat shock protein expression in avermectin induced neurotoxicity of the pigeon (Columba livia) both in vivo and in vitro.
Topics: Animals; Brain; Chaperonin 60; Columbidae; Gene Expression Regulation; HSP70 Heat-Shock Proteins; HSP90 Heat-Shock Proteins; Ivermectin; Lethal Dose 50; Protein Biosynthesis; RNA, Messenger; Transcription, Genetic | 2014 |
Identification and functional expression of a glutamate- and avermectin-gated chloride channel from Caligus rogercresseyi, a southern Hemisphere sea louse affecting farmed fish.
Topics: Amino Acid Sequence; Animals; Caenorhabditis elegans; Chloride Channels; Cloning, Molecular; Copepoda; Electrophysiology; Female; Fish Diseases; Fishes; Glutamic Acid; Insecticides; Ivermectin; Models, Molecular; Molecular Docking Simulation; Molecular Sequence Data; Oocytes; Sequence Homology, Amino Acid; Xenopus laevis | 2014 |
Adhesive polydopamine coated avermectin microcapsules for prolonging foliar pesticide retention.
Topics: Adhesives; Capsules; Crops, Agricultural; Indoles; Ivermectin; Microscopy, Electron, Scanning; Pesticides; Polymerization; Polymers; Spectroscopy, Fourier Transform Infrared | 2014 |
Effects of avermectin on heat shock proteins expression and histopathology in spleen tissues of pigeon.
Topics: Animals; Antiparasitic Agents; Columbidae; Environmental Pollutants; Heat-Shock Proteins; Ivermectin; RNA, Messenger; Spleen; Transcription, Genetic | 2014 |
Ternary toxicological interactions of insecticides, herbicides, and a heavy metal on the earthworm Eisenia fetida.
Topics: Acetanilides; Animals; Atrazine; Cadmium; Chlorpyrifos; Herbicides; Imidazoles; Insecticides; Ivermectin; Metals, Heavy; Neonicotinoids; Nitriles; Nitro Compounds; Oligochaeta; Organothiophosphorus Compounds; Pyrethrins; Soil Pollutants; Toxicity Tests | 2015 |
Autophagy is upregulated in brain tissues of pigeons exposed to avermectin.
Topics: Animals; Autophagy; Brain; Columbidae; Dyneins; Insecticides; Ivermectin; Mechanistic Target of Rapamycin Complex 1; Mechanistic Target of Rapamycin Complex 2; Multiprotein Complexes; Random Allocation; RNA, Messenger; TOR Serine-Threonine Kinases; Toxicity Tests; Up-Regulation | 2015 |
Purification, characterization, and sensitivity to pesticides of carboxylesterase from Dendrolimus superans (Lepidoptera: Lasiocampidae).
Topics: Animals; Carboxylesterase; Dichlorvos; Enzyme Inhibitors; Insecticides; Ivermectin; Kinetics; Larva; Molecular Weight; Moths; Nitriles; Pesticides; Pyrethrins | 2014 |
Susceptibility of rapidly growing mycobacteria isolated from Australian cats to ivermectin, moxidectin, ceftiofur and florfenicol.
Topics: Animals; Anti-Bacterial Agents; Australia; Cat Diseases; Cats; Cephalosporins; Drug Combinations; Drug Resistance, Bacterial; Ivermectin; Macrolides; Microbial Sensitivity Tests; Mycobacterium; Mycobacterium fortuitum; Mycobacterium Infections; Thiamphenicol | 2015 |
Structural and functional analysis of the loading acyltransferase from avermectin modular polyketide synthase.
Topics: Acyltransferases; Base Sequence; Butyrates; Catalytic Domain; Crystallography, X-Ray; Hydrolysis; Ivermectin; Models, Molecular; Molecular Sequence Data; Polyketide Synthases; Protein Engineering; Protein Structure, Tertiary; Stereoisomerism; Streptomyces; Substrate Specificity | 2015 |
1,19-seco-Avermectin analogues from a ΔaveCDE mutant Streptomyces avermectinius strain.
Topics: Animals; Antineoplastic Agents; Drug Screening Assays, Antitumor; Humans; Ivermectin; Mice; Molecular Structure; Mutation; Streptomyces | 2015 |
The synergistic toxicity of the multiple chemical mixtures: implications for risk assessment in the terrestrial environment.
Topics: Acetanilides; Animals; Atrazine; Cadmium; Chlorpyrifos; Drug Synergism; Herbicides; Imidazoles; Insecticides; Ivermectin; Metals, Heavy; Neonicotinoids; Nitriles; Nitro Compounds; Oligochaeta; Organothiophosphorus Compounds; Pesticides; Pyrethrins; Risk Assessment; Soil Pollutants | 2015 |
Synergistic effect of non-ionic surfactants Tween 80 and PEG6000 on cytotoxicity of insecticides.
Topics: Animals; Benzamides; Cell Line; Cell Survival; Chlorpyrifos; Drug Interactions; Hep G2 Cells; Humans; Hydrazines; Insecticides; Ivermectin; Lepidoptera; Phenylurea Compounds; Polyethylene Glycols; Polysorbates; Pyridines; Surface-Active Agents | 2015 |
In-vitro activity of avermectins against Mycobacterium ulcerans.
Topics: Administration, Oral; Buruli Ulcer; Ivermectin; Microbial Sensitivity Tests; Mycobacterium ulcerans; Rifampin; Streptomycin | 2015 |
Determination of avermectins: a QuEChERS approach to the analysis of food samples.
Topics: Chromatography, Liquid; Food Analysis; Ivermectin; Mass Spectrometry; Molecular Structure; Tandem Mass Spectrometry | 2015 |
Fast and Online Determination of Five Avermectin Residues in Foodstuffs of Plant and Animal Origin Using Reusable Polymeric Monolithic Extractor Coupled with LC-MS/MS.
Topics: Animals; Anti-Bacterial Agents; Automation; Capsicum; Cattle; Chromatography, High Pressure Liquid; Food Contamination; Fruit; Ivermectin; Limit of Detection; Meat; Milk; Molecular Structure; Polymers; Pyrus; Seeds; Solid Phase Extraction; Tandem Mass Spectrometry | 2015 |
Characterization of multidrug transporter-mediated efflux of avermectins in human and mouse neuroblastoma cell lines.
Topics: Animals; Antineoplastic Agents; ATP-Binding Cassette Transporters; Cell Line, Tumor; Drug Resistance, Neoplasm; Gene Expression Regulation; Genes, MDR; Humans; Ivermectin; Mice; Neuroblastoma; RNA, Messenger | 2015 |
[Treatment for toxic encephalopathy caused by compound preparation of avermectins and pyridaben].
Topics: Drug Compounding; Ivermectin; Neurotoxicity Syndromes; Pyridazines | 2015 |
Mosquitocidal properties of IgG targeting the glutamate-gated chloride channel in three mosquito disease vectors (Diptera: Culicidae).
Topics: Aedes; Amino Acid Sequence; Animals; Anopheles; Antigens; Chloride Channels; Culex; Female; Hemolymph; Immunoglobulin G; Insect Control; Insect Vectors; Insecticides; Ivermectin; Molecular Sequence Data; Species Specificity | 2015 |
Increasing Avermectin Production in Streptomyces avermitilis by Manipulating the Expression of a Novel TetR-Family Regulator and Its Target Gene Product.
Topics: Anthelmintics; DNA, Bacterial; Electrophoretic Mobility Shift Assay; Encephalitis Virus, California; Gene Deletion; Gene Expression; Gene Expression Regulation, Bacterial; Ivermectin; Metabolic Engineering; Protein Binding; Streptomyces; Transcription Factors | 2015 |
Gene Replacement for the Generation of Designed Novel Avermectin Derivatives with Enhanced Acaricidal and Nematicidal Activities.
Topics: Acaricides; Animals; Anthelmintics; Ivermectin; Metabolic Engineering; Molecular Structure; Parasitic Sensitivity Tests; Streptomyces; Survival Analysis; Tetranychidae; Tylenchida | 2015 |
Selective Inhibition of SIN3 Corepressor with Avermectins as a Novel Therapeutic Strategy in Triple-Negative Breast Cancer.
Topics: Animals; Antigens, CD; Antiparasitic Agents; Cadherins; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Drug Resistance, Neoplasm; Estrogen Receptor alpha; Female; Gene Expression Regulation, Neoplastic; Humans; Ivermectin; Mice; Models, Molecular; Molecular Conformation; Protein Interaction Domains and Motifs; Repressor Proteins; Triple Negative Breast Neoplasms; Tumor Burden; Xenograft Model Antitumor Assays | 2015 |
Targeting the Osmotic Stress Response for Strain Improvement of an Industrial Producer of Secondary Metabolites.
Topics: Anti-Bacterial Agents; Gene Deletion; Gene Regulatory Networks; Ivermectin; Metabolic Engineering; Oligomycins; Osmoregulation; Streptomyces | 2015 |
Satoshi Ōmura.
Topics: Animals; Biological Products; Drug Discovery; History, 20th Century; History, 21st Century; Humans; Ivermectin; Japan | 2016 |
The effects of some avermectins on bovine carbonic anhydrase enzyme.
Topics: Acetazolamide; Animals; Antiparasitic Agents; Carbonic Anhydrases; Cattle; Disaccharides; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Erythrocytes; Ivermectin; Macrolides; Molecular Structure | 2016 |
The PhoP transcription factor negatively regulates avermectin biosynthesis in Streptomyces avermitilis.
Topics: Anti-Bacterial Agents; Bacterial Proteins; DNA Footprinting; DNA, Bacterial; Electrophoretic Mobility Shift Assay; Gene Deletion; Ivermectin; Phosphates; Protein Binding; Streptomyces; Transcription Factors | 2015 |
Isolation, characterization, and tissue-specific expression of GABA A receptor α1 subunit gene of Carassius auratus gibelio after avermectin treatment.
Topics: Amino Acid Sequence; Animals; Antiparasitic Agents; Base Sequence; Brain; Cloning, Molecular; DNA, Complementary; Fish Proteins; Gene Expression; Goldfish; Ivermectin; Kidney; Liver; Molecular Sequence Data; Neurotoxins; Phylogeny; Protein Isoforms; Receptors, GABA-A; RNA, Messenger | 2016 |
Doxycycline as an inhibitor of p-glycoprotein in the alpaca for the purpose of maintaining avermectins in the CNS during treatment for parelaphostrongylosis.
Topics: Amino Acid Sequence; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Camelids, New World; Cell Line; Central Nervous System Diseases; Dogs; Doxycycline; Drug Interactions; Gene Expression Regulation; Ivermectin; Minocycline; Molecular Sequence Data | 2015 |
Designed biosynthesis of 25-methyl and 25-ethyl ivermectin with enhanced insecticidal activity by domain swap of avermectin polyketide synthase.
Topics: Animals; Gene Expression Regulation, Bacterial; Insecticides; Ivermectin; Models, Molecular; Polyketide Synthases | 2015 |
2015 Nobel Prize goes to antiparasitic drug discoverers.
Topics: Antiparasitic Agents; Artemisinins; Drug Discovery; Humans; Ivermectin; Nobel Prize | 2015 |
Editorial: on artemisinin, avermectins and Nobel Prizes.
Topics: Anti-Infective Agents; Antiparasitic Agents; Artemisinins; Humans; Ivermectin; Nobel Prize | 2015 |
Celebrating the 2015 Nobel Prize in Physiology or Medicine of Dr Satoshi Ōmura.
Topics: Anthelmintics; Chemistry, Pharmaceutical; HEK293 Cells; Helminthiasis; History, 20th Century; History, 21st Century; Humans; Ivermectin; Japan; Nobel Prize | 2016 |
[Determination of five avermectins in bovine liver by on-line solid-phase extraction with hydrophobic monolithic column coupled with high performance liquid chromatography-tandem mass spectrometry].
Topics: Animals; Cattle; Chromatography, High Pressure Liquid; Hydrophobic and Hydrophilic Interactions; Ivermectin; Liver; Methacrylates; Solid Phase Extraction; Tandem Mass Spectrometry | 2015 |
Avermectin induced autophagy in pigeon spleen tissues.
Topics: Animals; Autophagy; Biomarkers; Columbidae; Environmental Pollutants; Gene Expression Regulation; Ivermectin; Spleen | 2015 |
Reflections on the Nobel Prize for Medicine 2015--The Public Health Legacy and Impact of Avermectin and Artemisinin.
Topics: Animals; Antiparasitic Agents; Artemisinins; Drug Industry; Global Health; History, 20th Century; History, 21st Century; Humans; Ivermectin; Nobel Prize; Parasitic Diseases; Public Health; World Health Organization | 2015 |
Nobel Prize for artemisinin brings phytotherapy into the spotlight.
Topics: Anthelmintics; Antimalarials; Artemisia; Artemisinins; History, 21st Century; Ivermectin; Nobel Prize; Phytotherapy; Streptomyces; Sweden | 2015 |
Preparation of uniform starch microcapsules by premix membrane emulsion for controlled release of avermectin.
Topics: Capsules; Emulsions; Glass; Insecticides; Ivermectin; Membranes, Artificial; Starch | 2016 |
Selective targeting of nuclear receptor FXR by avermectin analogues with therapeutic effects on nonalcoholic fatty liver disease.
Topics: Animals; Drug Delivery Systems; Drug Evaluation, Preclinical; Ivermectin; Mice; Mice, Knockout; Non-alcoholic Fatty Liver Disease; Receptors, Cytoplasmic and Nuclear | 2015 |
A New Golden Age of Natural Products Drug Discovery.
Topics: Artemisinins; Drug Discovery; History of Medicine; History, 21st Century; Ivermectin; Nobel Prize; Parasitic Diseases; Physiology | 2015 |
Introduction to the Special Issue: "Natural Product Discovery and Development in the Genomic Era".
Topics: Biological Products; Drug Discovery; Genomics; Humans; Ivermectin; Nobel Prize; Onchocerciasis, Ocular | 2016 |
Nobel prize for the artemisinin and ivermectin discoveries: a great boost towards elimination of the global infectious diseases of poverty.
Topics: Anti-Infective Agents; Antiprotozoal Agents; Artemisinins; Communicable Disease Control; Communicable Diseases; Global Health; History, 21st Century; Humans; Ivermectin; Nobel Prize | 2015 |
Characterisation of P-glycoprotein-9.1 in Haemonchus contortus.
Topics: Animals; Anthelmintics; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Female; Gene Expression Profiling; Genitalia, Female; Haemonchus; Ivermectin; Macrolides; Protein Binding; Real-Time Polymerase Chain Reaction | 2016 |
The Nobel Prize 2015 in physiology or medicine for highly effective antiparasitic drugs.
Topics: Anthelmintics; Antimalarials; Artemisinins; China; History, 21st Century; Humans; Ivermectin; Japan; Nobel Prize; Parasitology; Sweden; United States | 2015 |
Introduction.
Topics: Actinobacteria; Animals; Anthelmintics; Genomics; Helminths; Humans; Ivermectin; Parasitic Diseases, Animal; Synthetic Biology | 2016 |
Autophagy response in the liver of pigeon exposed to avermectin.
Topics: Animals; Autophagy; Columbidae; Insecticides; Ivermectin; Liver | 2017 |
[Nobel prize for ivermectin].
Topics: Anthelmintics; Antimalarials; Artemisinins; China; Drugs, Chinese Herbal; History, 21st Century; Ivermectin; Japan; New Jersey; Nobel Prize; Parasitology | 2016 |
Different fates of avermectin and artemisinin in China.
Topics: Anthelmintics; Antimalarials; Artemisinins; China; Ivermectin | 2016 |
Multiresidue method for simultaneous analysis of aflatoxin M1, avermectins, organophosphate pesticides and milbemycin in milk by ultra-performance liquid chromatography coupled to tandem mass spectrometry.
Topics: Aflatoxin M1; Animals; Brazil; Chromatography, High Pressure Liquid; Food Contamination; Ivermectin; Macrolides; Milk; Organophosphates; Pesticide Residues; Reproducibility of Results; Tandem Mass Spectrometry | 2016 |
Raising the avermectins production in Streptomyces avermitilis by utilizing nanosecond pulsed electric fields (nsPEFs).
Topics: Anthelmintics; Bacterial Proteins; Electric Stimulation; Fermentation; Gene Expression Regulation, Bacterial; Insecticides; Ivermectin; Oxidation-Reduction; Streptomyces; Temperature | 2016 |
Preparation, Characterization, and Insecticidal Activity of Avermectin-Grafted-Carboxymethyl Chitosan.
Topics: Aminopyridines; Animals; Aphids; Chitosan; Dicyclohexylcarbodiimide; Esterification; Insecticides; Ivermectin; Magnetic Resonance Spectroscopy; Spectroscopy, Fourier Transform Infrared | 2016 |
Direct interaction of avermectin with epidermal growth factor receptor mediates the penetration resistance in Drosophila larvae.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chitin Synthase; Drosophila melanogaster; Drosophila Proteins; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Insecticide Resistance; Ivermectin; Larva; Models, Biological; Proto-Oncogene Proteins c-akt; Signal Transduction; Transcription Factors; Up-Regulation | 2016 |
Synthesis, biological activities and structure-activity relationships for new avermectin analogues.
Topics: Animals; Antinematodal Agents; Chemistry Techniques, Synthetic; Ivermectin; Mice; Nematoda; Quantitative Structure-Activity Relationship; Structure-Activity Relationship | 2016 |
[ECF-σ5 in Sreptomyces avermitilis is involved in regulation of avermectin biosynthesis and stress response].
Topics: Bacterial Proteins; Down-Regulation; Gene Expression Regulation, Bacterial; Ivermectin; Promoter Regions, Genetic; Sigma Factor; Streptomyces | 2016 |
AvaR2, a pseudo γ-butyrolactone receptor homologue from Streptomyces avermitilis, is a pleiotropic repressor of avermectin and avenolide biosynthesis and cell growth.
Topics: 4-Butyrolactone; Anthelmintics; Anti-Bacterial Agents; Bacterial Proteins; Ivermectin; Multigene Family; Promoter Regions, Genetic; Receptors, GABA-A; Repressor Proteins; Streptomyces; Transcription Factors | 2016 |
Development, validation, and application of a method for selected avermectin determination in rural waters using high performance liquid chromatography and fluorescence detection.
Topics: Brazil; Chromatography, High Pressure Liquid; Environmental Monitoring; Fluorescence; Ivermectin; Rivers; Solid Phase Extraction; Spectrometry, Fluorescence; Water | 2016 |
Enhanced production of avermectin by deletion of type III polyketide synthases biosynthetic cluster rpp in Streptomyces avermitilis.
Topics: Acyltransferases; Gene Deletion; Genetic Engineering; Industrial Microbiology; Ivermectin; Malonyl Coenzyme A; Multigene Family; Polyketide Synthases; Polymerase Chain Reaction; Streptomyces | 2016 |
Characterization of AvaR1, a butenolide-autoregulator receptor for biosynthesis of a Streptomyces hormone in Streptomyces avermitilis.
Topics: 4-Butyrolactone; Bacterial Proteins; Gene Expression Regulation, Bacterial; Gene Knockout Techniques; Ivermectin; Receptors, Cell Surface; Repressor Proteins; Streptomyces; Transcription, Genetic | 2016 |
Immune-physiological aspects of synergy between avermectins and the entomopathogenic fungus Metarhizium robertsii in Colorado potato beetle larvae.
Topics: Animals; Coleoptera; Insecticides; Ivermectin; Larva; Metarhizium; Pest Control, Biological | 2016 |
Avermectin Confers Its Cytotoxic Effects by Inducing DNA Damage and Mitochondria-Associated Apoptosis.
Topics: Apoptosis; Comet Assay; DNA Breaks, Double-Stranded; DNA Damage; HeLa Cells; Humans; Ivermectin; Membrane Potential, Mitochondrial; Mitochondria | 2016 |
Effects of in vitro and in vivo avermectin exposure on alpha synuclein expression and proteasomal activity in pigeons.
Topics: alpha-Synuclein; Animals; Brain; Cells, Cultured; China; Columbidae; Dose-Response Relationship, Drug; Environmental Monitoring; Environmental Pollutants; Ivermectin; Neurons; Primary Cell Culture; Proteasome Endopeptidase Complex; RNA, Messenger | 2017 |
From the Cover: Functional Analysis Reveals Glutamate and Gamma-Aminobutyric Acid-Gated Chloride Channels as Targets of Avermectins in the Carmine Spider Mite.
Topics: Amino Acid Sequence; Animals; Chloride Channels; gamma-Aminobutyric Acid; Glutamic Acid; Ivermectin; Mites; Sequence Homology, Amino Acid | 2017 |
Antiviral effect of theaflavins against caliciviruses.
Topics: Animals; Antiviral Agents; Biflavonoids; Caliciviridae; Caliciviridae Infections; Calicivirus, Feline; Catechin; Cats; Cytopathogenic Effect, Viral; Drug Evaluation, Preclinical; Flavins; Humans; Ivermectin; Mice; Norovirus; Protein Structure, Quaternary; Sapovirus; Structure-Activity Relationship | 2017 |
Cytotoxic effects of Avermectin on human HepG2 cells in vitro bioassays.
Topics: Animals; Anthelmintics; Apoptosis; bcl-2-Associated X Protein; Biological Assay; Caspase 3; Caspase 9; Chromatin; DNA Fragmentation; Environmental Pollutants; Hep G2 Cells; Humans; Ivermectin; Liver; Membrane Potential, Mitochondrial; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species | 2017 |
Preparation of magnetic molecularly imprinted polymers by atom transfer radical polymerization for the rapid extraction of avermectin from fish samples.
Topics: Adsorption; Animals; Chemistry Techniques, Analytical; Fishes; Ivermectin; Limit of Detection; Molecular Imprinting; Muscle, Skeletal; Nanotubes, Carbon; Polymerization; Polymers | 2017 |
Direct Involvement of the Master Nitrogen Metabolism Regulator GlnR in Antibiotic Biosynthesis in Streptomyces.
Topics: Bacterial Proteins; Ivermectin; Streptomyces; Trans-Activators | 2016 |
Epoch-making milestones in antibiotic exploratory researches in Japan.
Topics: Aminoglycosides; Anti-Bacterial Agents; Drug Discovery; History, 20th Century; History, 21st Century; Humans; Ivermectin; Japan; Research | 2017 |
Anecdote of the Ōmura laboratory and the discovery of avermectin.
Topics: Academies and Institutes; Drug Discovery; History, 20th Century; History, 21st Century; Humans; Ivermectin; Laboratories | 2017 |
Inhibition of Plasmodium Liver Infection by Ivermectin.
Topics: Animals; Cell Line, Tumor; Culicidae; Humans; Ivermectin; Liver; Malaria; Plasmodium | 2017 |
Comparative metabolomics reveals the mechanism of avermectin production enhancement by S-adenosylmethionine.
Topics: Amino Acids; Carbon; Culture Media; Fatty Acids; Gas Chromatography-Mass Spectrometry; Ivermectin; Metabolomics; Principal Component Analysis; S-Adenosylmethionine; Streptomyces | 2017 |
Avermectin induced global DNA hypomethylation and over-expression of heat shock proteins in cardiac tissues of pigeon.
Topics: Animals; Avian Proteins; Columbidae; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA-Binding Proteins; Heat-Shock Proteins; Ivermectin; Myocardium; Pesticides; RNA, Messenger | 2017 |
Pesticide-mediated interspecific competition between local and invasive thrips pests.
Topics: Animals; Biological Assay; Competitive Behavior; Female; Introduced Species; Ivermectin; Pesticides; Plant Leaves; Pyrethrins; Species Specificity; Thysanoptera | 2017 |
Engineered biosynthesis of milbemycins in the avermectin high-producing strain Streptomyces avermitilis.
Topics: Anti-Bacterial Agents; Biosynthetic Pathways; Fermentation; Insecticides; Ivermectin; Macrolides; Methyltransferases; Molecular Structure; Polyketide Synthases; Streptomyces | 2017 |
A spectrophotometric screening method for avermectin oxidizing microorganisms.
Topics: Bacteria; Chromatography, High Pressure Liquid; DNA, Bacterial; Enzymes; Ivermectin; Oxidants; Oxidation-Reduction; Phenylhydrazines; RNA, Ribosomal, 16S; Spectrophotometry; Streptomyces | 2017 |
Phenotypic Screening Identifies Modulators of Amyloid Precursor Protein Processing in Human Stem Cell Models of Alzheimer's Disease.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Anthelmintics; Cells, Cultured; Down Syndrome; Drug Discovery; Humans; Induced Pluripotent Stem Cells; Ivermectin; Neurogenesis; Neurons; Phenotype | 2017 |
Redox-sensing regulator Rex regulates aerobic metabolism, morphological differentiation, and avermectin production in Streptomyces avermitilis.
Topics: Aerobiosis; Binding Sites; Cell Differentiation; Cell Respiration; DNA-Binding Proteins; Gene Expression Regulation, Bacterial; Gene Products, rex; Ivermectin; Oxidation-Reduction; Promoter Regions, Genetic; Protein Binding; Streptomyces; Transcription, Genetic | 2017 |
New Avermectin Analogues from a Mutant Streptomyces avermectinius Strain.
Topics: Antineoplastic Agents; Cell Death; Cell Line, Tumor; Humans; Ivermectin; Melanoma, Experimental; Molecular Structure; Mutation; Spectrum Analysis; Streptomyces | 2017 |
Analysis of sulfonamides, tilmicosin and avermectins residues in typical animal matrices with multi-plug filtration cleanup by liquid chromatography-tandem mass spectrometry detection.
Topics: Animals; Anti-Infective Agents; Cattle; Chromatography, High Pressure Liquid; Filtration; Food Analysis; Food Contamination; Goats; Hexanes; Humans; Ivermectin; Limit of Detection; Meat; Milk; Sonication; Sulfonamides; Swine; Tandem Mass Spectrometry; Tylosin; Veterinary Drugs | 2017 |
Low sensitivity of reproductive life-stages in the Pacific oyster (Crassostrea gigas) to abamectin.
Topics: Animals; Crassostrea; Fertilization; Ivermectin; Larva; Life Cycle Stages; Paint; Reproduction; Water Pollutants, Chemical | 2017 |
Multiresidue method for identification and quantification of avermectins, benzimidazoles and nitroimidazoles residues in bovine muscle tissue by ultra-high performance liquid chromatography tandem mass spectrometry (UHPLC-MS/MS) using a QuEChERS approach.
Topics: Analytic Sample Preparation Methods; Animals; Benzimidazoles; Cattle; Chemical Fractionation; Chromatography, High Pressure Liquid; Drug Residues; Ivermectin; Limit of Detection; Muscles; Nitroimidazoles; Tandem Mass Spectrometry | 2017 |
Preparation and Characterization of Controlled-Release Avermectin/Castor Oil-Based Polyurethane Nanoemulsions.
Topics: Castor Oil; Delayed-Action Preparations; Drug Carriers; Drug Compounding; Drug Delivery Systems; Emulsions; Insecticides; Ivermectin; Polyurethanes; Temperature | 2018 |
Determination of avermectins by the internal standard recovery correction - high performance liquid chromatography - quantitative Nuclear Magnetic Resonance method.
Topics: Chromatography, High Pressure Liquid; Ivermectin; Linear Models; Magnetic Resonance Spectroscopy; Reference Standards; Tandem Mass Spectrometry | 2017 |
Avermectin biosynthesis: stable functional expression of branched chain α-keto acid dehydrogenase complex from Streptomyces avermitilis in Escherichia coli by selectively regulating individual subunit gene expression.
Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Bacterial Proteins; Cloning, Molecular; Escherichia coli; Ivermectin; Multienzyme Complexes; Multigene Family; Streptomyces | 2017 |
Fabrication of Novel Avermectin Nanoemulsion Using a Polyurethane Emulsifier with Cleavable Disulfide Bonds.
Topics: Animals; Disulfides; Drug Compounding; Emulsifying Agents; Emulsions; Insecticides; Ivermectin; Moths; Polyurethanes | 2018 |
Bioinspired Development of P(St-MAA)-Avermectin Nanoparticles with High Affinity for Foliage To Enhance Folia Retention.
Topics: Adhesives; Animals; Bivalvia; Brassica; Cucumis sativus; Drug Carriers; Drug Compounding; Drug Delivery Systems; Drug Stability; Ivermectin; Nanoparticles; Pesticides; Plant Leaves; Polymers | 2018 |
Activation of cryptic phthoxazolin A production in Streptomyces avermitilis by the disruption of autoregulator-receptor homologue AvaR3.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Biological Assay; Fatty Alcohols; Gene Expression Regulation, Bacterial; Ivermectin; Multigene Family; Oomycetes; Oxazoles; Polyunsaturated Alkamides; Secondary Metabolism; Streptomyces | 2017 |
A G326E substitution in the glutamate-gated chloride channel 3 (GluCl3) of the two-spotted spider mite Tetranychus urticae abolishes the agonistic activity of macrocyclic lactones.
Topics: Acaricides; Amino Acid Substitution; Animals; Arthropod Proteins; Chloride Channels; Ivermectin; Lactones; Mutation, Missense; Tetranychidae; Xenopus laevis | 2017 |
Evaluation of the safe use and dietary risk of beta-cypermethrin, pyriproxyfen, avermectin, diflubenzuron and chlorothalonil in button mushroom.
Topics: Agaricus; Calibration; Diet; Diflubenzuron; Half-Life; Ivermectin; Limit of Detection; Nitriles; Pesticide Residues; Pyrethrins; Pyridines; Regression Analysis; Risk Assessment; Risk Factors; Soil; Solvents | 2017 |
Study of the degradation in aqueous solution of a refractory organic compound: avermectin type used as pesticide in agriculture.
Topics: Biodegradation, Environmental; Biological Oxygen Demand Analysis; Electrolysis; Hydrogen Peroxide; Iron; Ivermectin; Organic Chemicals; Pesticides; Water; Water Pollutants, Chemical | 2017 |
Genome-wide identification, phylogenetic analysis, and expression profiles of ATP-binding cassette transporter genes in the oriental fruit fly, Bactrocera dorsalis (Hendel) (Diptera: Tephritidae).
Topics: Animals; ATP-Binding Cassette Transporters; Databases, Genetic; Gene Expression Profiling; Genome, Insect; Inactivation, Metabolic; Insect Proteins; Insecticide Resistance; Insecticides; Ivermectin; Lethal Dose 50; Malathion; Phylogeny; Pyrethrins; RNA Interference; RNA, Messenger; Tephritidae; Transcriptome; Up-Regulation | 2018 |
Enhanced avermectin production by Streptomyces avermitilis ATCC 31267 using high-throughput screening aided by fluorescence-activated cell sorting.
Topics: Antiprotozoal Agents; Bioreactors; Flow Cytometry; Fluorescent Dyes; Gene Expression Regulation, Bacterial; High-Throughput Screening Assays; Ivermectin; Mutagenesis; Spores; Streptomyces | 2018 |
Motility in the L3 stage is a poor phenotype for detecting and measuring resistance to avermectin/milbemycin drugs in gastrointestinal nematodes of livestock.
Topics: Animals; Anthelmintics; Drug Resistance, Multiple; Gastrointestinal Tract; Haemonchus; Ivermectin; Larva; Livestock; Macrolides; Movement; Nematoda; Phenotype; Sheep; Sheep Diseases; Trichostrongyloidea | 2018 |
Characterization and evaluation of avermectin solid nanodispersion prepared by microprecipitation and lyophilisation techniques.
Topics: Biological Assay; Freeze Drying; Insecticides; Ivermectin; Nanotechnology; Solubility; Water; Wettability | 2018 |
Chitosan-based nanoparticles of avermectin to control pine wood nematodes.
Topics: Animals; Chitosan; Ivermectin; Nanoparticles; Nematoda; Pest Control; Pinus; Wood | 2018 |
Butenolides from Streptomyces albus J1074 Act as External Signals To Stimulate Avermectin Production in Streptomyces avermitilis.
Topics: 4-Butyrolactone; Bacterial Proteins; Gene Expression; Ivermectin; Mass Spectrometry; Metabolome; Secondary Metabolism; Species Specificity; Streptomyces | 2018 |
Modified Lignin with Anionic Surfactant and Its Application in Controlled Release of Avermectin.
Topics: Delayed-Action Preparations; Drug Carriers; Drug Delivery Systems; Insecticides; Ivermectin; Kinetics; Lignin; Surface-Active Agents | 2018 |
Avermectin toxicity in bovines less than thirty days old.
Topics: Animals; Animals, Newborn; Anthelmintics; Cattle; Injections, Subcutaneous; Ivermectin | 2018 |
[Sublethal effects of fenpropathrin and avermectin on Panonychus citri (Acari: Tereanychidae).]
Topics: Animals; Female; Insecticides; Ivermectin; Male; Oviposition; Pest Control; Pyrethrins; Reproduction; Tetranychidae | 2016 |
[Enhanced avermectin production by rational feeding strategies based on comparative metabolomics].
Topics: Bacterial Proteins; Culture Media; Fermentation; Gene Expression Regulation, Bacterial; Ivermectin; Metabolic Networks and Pathways; Metabolomics; Streptomyces | 2017 |
Fabrication of an Effective Avermectin Nanoemulsion Using a Cleavable Succinic Ester Emulsifier.
Topics: Animals; Aphids; Drug Carriers; Drug Compounding; Emulsifying Agents; Emulsions; Esters; Insecticides; Ivermectin; Nanoparticles; Succinates | 2018 |
α-Amylase triggered carriers based on cyclodextrin anchored hollow mesoporous silica for enhancing insecticidal activity of avermectin against Plutella xylostella.
Topics: alpha-Amylases; alpha-Cyclodextrins; Animals; Drug Carriers; Insecticides; Ivermectin; Larva; Lepidoptera; Porosity; Silicon Dioxide | 2018 |
Comparative effects of the parasiticide ivermectin on survival and reproduction of adult sepsid flies.
Topics: Animals; Antiparasitic Agents; Diptera; Ecology; Ecosystem; Feces; Female; Fertility; Insecta; Ivermectin; Life Cycle Stages; Livestock; Male; Phylogeny; Reproduction; Veterinary Drugs | 2018 |
The toxicological impact of some avermectins on human erythrocytes glutathione S-transferase enzyme.
Topics: Antiparasitic Agents; Chromatography, Affinity; Electrophoresis, Polyacrylamide Gel; Erythrocytes; Glutathione Transferase; Humans; Inhibitory Concentration 50; Ivermectin | 2018 |
Sorption behaviors of antimicrobial and antiparasitic veterinary drugs on subtropical soils.
Topics: Adsorption; Animals; Anti-Bacterial Agents; Antiparasitic Agents; Brazil; Fluoroquinolones; Ivermectin; Soil; Soil Pollutants; Sulfonamides; Thiabendazole; Veterinary Drugs | 2019 |
Effect of external resistance on the sensitivity of microbial fuel cell biosensor for detection of different types of pollutants.
Topics: Bacteria; Bioelectric Energy Sources; Biosensing Techniques; Electric Impedance; Electrodes; Equipment Design; Ivermectin; Metals, Heavy; Tetracyclines; Water Pollutants, Chemical | 2019 |
Ionization study and simultaneous determination of avermectins and milbemycines in fish tissue by LC-ESI-MS/MS.
Topics: Animals; Chromatography, Liquid; Fishes; Ivermectin; Limit of Detection; Linear Models; Macrolides; Reproducibility of Results; Seafood; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2019 |
Preparation of pH-responsive avermectin/feather keratin-hyaluronic acid with anti-UV and sustained-release properties.
Topics: Animals; Chickens; Delayed-Action Preparations; Drug Carriers; Drug Compounding; Drug Liberation; Feathers; Hyaluronic Acid; Hydrogen-Ion Concentration; Ivermectin; Keratins; Spectroscopy, Fourier Transform Infrared; Temperature; Ultraviolet Rays | 2019 |
Avermectins, praziquantel and levamisole have in vitro efficacy against Neoechinorhynchus buttnerae (Neoechinorhynchidae) in Colossoma macropomum: A Serrasalmidae from the Amazon.
Topics: Acanthocephala; Animals; Anthelmintics; Aquaculture; Brazil; Fish Diseases; Fishes; Helminthiasis, Animal; Ivermectin; Levamisole; Praziquantel | 2019 |
Development of a broad-spectrum monoclonal antibody-based indirect competitive enzyme-linked immunosorbent assay for the multi-residue detection of avermectins in edible animal tissues and milk.
Topics: Animals; Antibodies, Monoclonal; Antigens; Binding, Competitive; Enzyme-Linked Immunosorbent Assay; Female; Haptens; Ivermectin; Limit of Detection; Mice; Mice, Inbred BALB C; Milk; Reference Standards | 2019 |
Molecular cloning, characterization and functional analysis of GluCl from the oriental armyworm, Mythimna separata Walker.
Topics: Alternative Splicing; Animals; Chloride Channels; Cloning, Molecular; DNA, Complementary; Insecticides; Ivermectin; Moths; RNA, Messenger | 2019 |
Cu/ZnSOD always responded stronger and rapider than MnSOD in Lymantria dispar larvae under the avermectin stress.
Topics: Amino Acid Sequence; Animals; Computational Biology; DNA, Complementary; Ivermectin; Larva; Molecular Sequence Data; Moths; Pesticides; Polymerase Chain Reaction; Superoxide Dismutase | 2019 |
Enzyme and pH dual-responsive avermectin nano-microcapsules for improving its efficacy.
Topics: Capsules; Carboxymethylcellulose Sodium; Hydrogen-Ion Concentration; Ivermectin; Particle Size; Pesticides; Polyethylenes; Polymerization; Quaternary Ammonium Compounds; Ultraviolet Rays | 2019 |
Pesticide Residues Identification by Optical Spectrum in the Time-Sequence of Enzyme Inhibitors Performed on Microfluidic Paper-Based Analytical Devices (µPADs).
Topics: Cluster Analysis; Enzyme Inhibitors; Ivermectin; Lab-On-A-Chip Devices; Neonicotinoids; Nitro Compounds; Optics and Photonics; Paper; Pesticide Residues; Phorate; Time Factors | 2019 |
Repeated evolution of cytochrome P450-mediated spiroketal steroid biosynthesis in plants.
Topics: Anti-Bacterial Agents; Biosynthetic Pathways; Cholesterol; Cytochrome P-450 Enzyme System; Cytochromes; Diosgenin; Furans; Galactogogues; Gene Expression Profiling; Ivermectin; Lipogenesis; Melanthiaceae; Metabolomics; Plant Growth Regulators; Spiro Compounds; Trigonella | 2019 |
Characterization and Biological Action of Avermectin Granules on the Moroccan Locust, Dociostaurus maroccanus (Orthoptera: Acrididae).
Topics: Animals; Chromatography, High Pressure Liquid; Grasshoppers; Ivermectin; Nymph | 2019 |
Uptake, translocation and subcellular distribution of pesticides in Chinese cabbage (Brassica rapa var. chinensis).
Topics: Aza Compounds; Biological Transport; Brassica rapa; Humans; Hydroponics; Ivermectin; Nitriles; Pesticides; Plant Roots; Spiro Compounds; Thiamethoxam; Triazoles | 2019 |
Aerobic dissipation of avermectins and moxidectin in subtropical soils and dissipation of abamectin in a field study.
Topics: Antiparasitic Agents; Brazil; Environmental Monitoring; Half-Life; Ivermectin; Macrolides; Pesticides; Soil; Soil Pollutants | 2019 |
Preparation and performance of a BTDA-modified polyurea microcapsule for encapsulating avermectin.
Topics: Benzophenones; Capsules; Chitosan; Cross-Linking Reagents; Delayed-Action Preparations; Drug Compounding; Drug Liberation; Half-Life; Insecticides; Isocyanates; Ivermectin; Kinetics; Photolysis; Polymerization; Polymers; Sunlight | 2019 |
AveI, an AtrA homolog of Streptomyces avermitilis, controls avermectin and oligomycin production, melanogenesis, and morphological differentiation.
Topics: Biological Products; Gene Expression Regulation, Bacterial; Ivermectin; Melanins; Oligomycins; Streptomyces; Transcription Factors | 2019 |
Phosphorylated Zein as Biodegradable and Aqueous Nanocarriers for Pesticides with Sustained-Release and anti-UV Properties.
Topics: Animals; Delayed-Action Preparations; Drug Carriers; Drug Compounding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Insecticides; Ivermectin; Kinetics; Moths; Nanoparticles; Phosphorylation; Polyphosphates; Ultraviolet Rays; Zein | 2019 |
Synthesis and Characterization of Cry2Ab-AVM Bioconjugate: Enhanced Affinity to Binding Proteins and Insecticidal Activity.
Topics: Animals; Bacillus thuringiensis; Bacillus thuringiensis Toxins; Bacterial Proteins; Endotoxins; Hemolysin Proteins; Insect Proteins; Insecticides; Ivermectin; Molecular Docking Simulation; Moths; Protein Binding | 2019 |
Coordination bonding-based polydopamine-modified mesoporous silica for sustained avermectin release.
Topics: Delayed-Action Preparations; Hydrogen-Ion Concentration; Indoles; Ivermectin; Nanoparticles; Polymers; Porosity; Silicon Dioxide | 2019 |
Oxidative stress, immunological response, and heat shock proteins induction in the Chinese Mitten Crab, Eriocheir sinensis following avermectin exposure.
Topics: Animals; Antioxidants; Brachyura; Cell Survival; Dose-Response Relationship, Drug; Heat-Shock Proteins; Hepatopancreas; Ivermectin; Oxidative Stress; Reactive Oxygen Species; Time Factors; Water Pollutants, Chemical | 2020 |
BldD, a master developmental repressor, activates antibiotic production in two Streptomyces species.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Daptomycin; DNA-Binding Proteins; Gene Expression Regulation, Bacterial; Ivermectin; Streptomyces; Transcription Factors | 2020 |
Inhibition of Plasmodium sporogonic stages by ivermectin and other avermectins.
Topics: Animals; Antiparasitic Agents; Disease Models, Animal; Disease Transmission, Infectious; Ivermectin; Malaria; Mice, Inbred BALB C; Oocysts; Plasmodium berghei | 2019 |
Avermectin induces the oxidative stress, genotoxicity, and immunological responses in the Chinese Mitten Crab, Eriocheir sinensis.
Topics: Animals; Aquaculture; Brachyura; Ivermectin; Mutagens; Oxidative Stress; Phagocytosis; Protein Carbonylation | 2019 |
Enzyme cum pH dual-responsive controlled release of avermectin from functional polydopamine microcapsules.
Topics: Capsules; Hydrogen-Ion Concentration; Indoles; Ivermectin; Particle Size; Polymers; Surface Properties; Urease | 2020 |
Avermectin inhibits neutrophil extracellular traps release by activating PTEN demethylation to negatively regulate the PI3K-ERK pathway and reducing respiratory burst in carp.
Topics: Animals; Antiparasitic Agents; Carps; Demethylation; Extracellular Traps; Fish Proteins; Ivermectin; MAP Kinase Signaling System; Neutrophils; Phosphatidylinositol 3-Kinases; PTEN Phosphohydrolase; Respiratory Burst; Water Pollutants, Chemical | 2020 |
Carboxymethyl cellulose capsulated zein as pesticide nano-delivery system for improving adhesion and anti-UV properties.
Topics: Capsules; Carboxymethylcellulose Sodium; Drug Compounding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Ivermectin; Nanoparticles; Particle Size; Pesticides; Polyethylenes; Quaternary Ammonium Compounds; Zein | 2020 |
Molecular characterization, expression and enzyme activity of three glutathione S-transferase genes from Eriocheir sinensis under pesticide stresses.
Topics: Amino Acid Sequence; Animals; Base Sequence; Brachyura; Gene Expression; Glutathione Transferase; Hepatopancreas; Inactivation, Metabolic; Insecticides; Ivermectin; Muscles; Pyrethrins; Trichlorfon | 2020 |
Fabrication of smart stimuli-responsive mesoporous organosilica nano-vehicles for targeted pesticide delivery.
Topics: alpha-Amylases; Animals; Drug Carriers; Drug Liberation; Drug Stability; Glutathione; Hydrogen-Ion Concentration; Insecticides; Ivermectin; Kinetics; Light; Moths; Nanoparticles; Oxidation-Reduction; Pest Control; Porosity; Silicon Dioxide; Starch | 2020 |
Preparation of self-dispersed lignin-based drug-loaded material and its application in avermectin nano-formulation.
Topics: Antiprotozoal Agents; Delayed-Action Preparations; Drug Carriers; Drug Compounding; Drug Stability; Ivermectin; Lignin; Microspheres; Nanoparticles; Particle Size; Photolysis; Spectrum Analysis; Theranostic Nanomedicine | 2020 |
[Effect of nitrogen on avermectins biosynthesis and its fermentation optimization based on carbon-dioxide evolution rate].
Topics: Carbon; Carbon Dioxide; China; Fermentation; Ivermectin; Nitrogen | 2020 |
Inhibition of TMEM16A Ca
Topics: Adenocarcinoma of Lung; Animals; Anoctamin-1; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Movement; Cell Proliferation; CHO Cells; Cricetulus; Ivermectin; Lung Neoplasms; Male; Membrane Potentials; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness; Signal Transduction; Tumor Burden | 2020 |
Avermectin stress varied structure and function of gut microbial community in Lymantria dispar asiatica (Lepidoptera: Lymantriidae) larvae.
Topics: Animals; Insecticides; Ivermectin; Larva; Lepidoptera; Moths | 2020 |
Carboxymethyl chitosan grafted trisiloxane surfactant nanoparticles with pH sensitivity for sustained release of pesticide.
Topics: Chitosan; Crop Protection; Insecticides; Ivermectin; Nanoparticles; Siloxanes; Surface-Active Agents | 2020 |
A Neurotoxic Insecticide Promotes Fungal Infection in Aedes aegypti Larvae by Altering the Bacterial Community.
Topics: Aedes; Animals; Antibiosis; Bacteria; Bacterial Load; Insecticides; Ivermectin; Larva; Metarhizium; Microbiota; Mosquito Control; Spores, Fungal | 2021 |
Deciphering the Biosynthesis of TDP-β-l-oleandrose in Avermectin.
Topics: Anti-Bacterial Agents; Computational Biology; Deoxy Sugars; DNA, Bacterial; Escherichia coli; Hexoses; Ivermectin; Methyltransferases; Molecular Structure; UDPglucose 4-Epimerase | 2020 |
Toxic Effects of Fine Plant Powder Impregnated With Avermectins on Mosquito Larvae and Nontarget Aquatic Invertebrates.
Topics: Aedes; Animals; Anopheles; Aquatic Organisms; Culex; Culicidae; Ecological Parameter Monitoring; Ephemeroptera; Food Chain; Insecticides; Invertebrates; Ivermectin; Larva; Mosquito Control; Odonata; Powders | 2021 |
Development of leaf-adhesive pesticide nanocapsules with pH-responsive release to enhance retention time on crop leaves and improve utilization efficiency.
Topics: Adhesives; Antiprotozoal Agents; Drug Liberation; Hydrogen Bonding; Hydrogen-Ion Concentration; Ivermectin; Molecular Structure; Nanocapsules; Particle Size; Pesticides; Plant Leaves; Surface Properties; Time Factors; Zea mays | 2021 |
Ras/Raf/MEK/ERK pathway axis mediated neurotoxicity induced by high-risk pesticide residue-Avermectin.
Topics: China; Extracellular Signal-Regulated MAP Kinases; Humans; Ivermectin; MAP Kinase Kinase Kinases; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase Kinases; Pesticide Residues; raf Kinases | 2021 |
Fungus Metarhizium robertsii and neurotoxic insecticide affect gut immunity and microbiota in Colorado potato beetles.
Topics: Animals; Coleoptera; Insecticides; Intestines; Ivermectin; Metarhizium; Signal Transduction | 2021 |
Natural rosin modified carboxymethyl cellulose delivery system with lowered toxicity for long-term pest control.
Topics: Animals; Carboxymethylcellulose Sodium; Drug Carriers; Drug Liberation; Half-Life; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Ivermectin; Larva; Nanoparticles; Particle Size; Pest Control; Pesticides; Resins, Plant; Ultraviolet Rays; Zebrafish | 2021 |
Avermectin induced DNA damage to the apoptosis and autophagy in human lung epithelial A549 cells.
Topics: A549 Cells; Apoptosis; Autophagy; Cell Proliferation; Cytochromes c; DNA Damage; Humans; Insecticides; Ivermectin; Lung; Membrane Potential, Mitochondrial; Mitochondria; Proto-Oncogene Proteins c-bcl-2 | 2021 |
A stable polyamine-modified zein-based nanoformulation with high foliar affinity and lowered toxicity for sustained avermectin release.
Topics: Animals; Drug Carriers; Humans; Ivermectin; Nanoparticles; Particle Size; Polyamines; Zebrafish; Zein | 2021 |
Avermectin induces toxic effects in insect nontarget cells involves DNA damage and its associated programmed cell death.
Topics: Animals; Apoptosis; Autophagy; Cell Line; Cell Proliferation; Cell Survival; DNA Damage; Insect Proteins; Ivermectin; Reactive Oxygen Species; Spodoptera | 2021 |
Genome mapping coupled with CRISPR gene editing reveals a P450 gene confers avermectin resistance in the beet armyworm.
Topics: Animals; Chromosome Mapping; Clustered Regularly Interspaced Short Palindromic Repeats; Cytochrome P-450 Enzyme System; Gene Editing; Genome; Insecticide Resistance; Insecticides; Ivermectin; Larva; Spodoptera | 2021 |
One-Pot Facile Synthesis of Double-Shelled Mesoporous Silica Microcapsules with an Improved Soft-Template Method for Sustainable Pest Management.
Topics: Animals; Capsules; Coordination Complexes; Copper; Delayed-Action Preparations; Drug Compounding; Drug Liberation; Green Chemistry Technology; Hydrogen-Ion Concentration; Ionic Liquids; Ivermectin; Pest Control; Pesticides; Porosity; Quaternary Ammonium Compounds; Silicon Dioxide; Solubility; Tannins; Time Factors; Tylenchoidea | 2021 |
Comparative study of the interaction of ivermectin with proteins of interest associated with SARS-CoV-2: A computational and biophysical approach.
Topics: alpha Karyopherins; Animals; Antiviral Agents; beta Karyopherins; Binding Sites; Coronavirus 3C Proteases; COVID-19; COVID-19 Drug Treatment; DNA Helicases; Humans; Ivermectin; Kinetics; Mice; Molecular Docking Simulation; Molecular Dynamics Simulation; Protein Binding; Protein Conformation; Protein Interaction Domains and Motifs; SARS-CoV-2; Thermodynamics | 2021 |
Why are Drosophila larvae more sensitive to avermectin than adults?
Topics: Animals; Drosophila melanogaster; Insecticide Resistance; Insecticides; Ivermectin; Larva | 2022 |
Basic Amino Acid-Modified Lignin-Based Biomass Adjuvants: Synthesis, Emulsifying Activity, Ultraviolet Protection, and Controlled Release of Avermectin.
Topics: Amino Acids, Basic; Biomass; Delayed-Action Preparations; Emulsions; Ivermectin; Lignin | 2021 |
Insecticide resistance to insect growth regulators, avermectins, spinosyns and diamides in Culex quinquefasciatus in Saudi Arabia.
Topics: Animals; Culex; Diamide; Drug Combinations; Insecticide Resistance; Insecticides; Ivermectin; Juvenile Hormones; Macrolides; Mosquito Vectors; Saudi Arabia | 2021 |
Synergistic effects of botanical curcumin-induced programmed cell death on the management of Spodoptera litura Fabricius with avermectin.
Topics: Animals; Apoptosis; Curcumin; Ivermectin; Larva; Spodoptera | 2022 |
The avermectin/milbemycin receptors of parasitic nematodes.
Topics: Animals; Caenorhabditis elegans; Chloride Channels; Ivermectin; Macrolides | 2022 |
Polylactic acid nanoparticles for co-delivery of dinotefuran and avermectin against pear tree pests with improved effective period and enhanced bioactivity.
Topics: Guanidines; Ivermectin; Nanoparticles; Neonicotinoids; Nitro Compounds; Pesticides; Polyesters; Pyrus; Trees | 2022 |
Avermectin Toxicity to Benthic Invertebrates is Modified by Sediment Organic Carbon and Chemical Residence Time.
Topics: Amphipoda; Animals; Carbon; Geologic Sediments; Invertebrates; Ivermectin; Water Pollutants, Chemical | 2022 |
Synthesis and evaluation of avermectin-imidazo[1,2-a]pyridine hybrids as potent GABA
Topics: Animals; Benzodiazepines; gamma-Aminobutyric Acid; Ivermectin; Pyridines; Rats; Receptors, GABA-A; Zebrafish | 2022 |
Avermectin induces carp neurotoxicity by mediating blood-brain barrier dysfunction, oxidative stress, inflammation, and apoptosis through PI3K/Akt and NF-κB pathways.
Topics: Animals; Apoptosis; Blood-Brain Barrier; Carps; Inflammation; Ivermectin; NF-kappa B; Oxidative Stress; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Tumor Necrosis Factor-alpha | 2022 |
Non-target toxic effects of avermectin on carp spleen involve oxidative stress, inflammation, and apoptosis.
Topics: Animals; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Carps; Caspase 3; Inflammation; Inflammation Mediators; Interleukin-10; Interleukin-6; Ivermectin; Oxidative Stress; Pesticides; Spleen; Superoxide Dismutase; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha; Tumor Suppressor Protein p53 | 2022 |
Implications of environmentally shaped microbial communities for insecticide resistance in Sitobion miscanthi.
Topics: Animals; Aphids; Bacteria; Enterobacteriaceae; Insecticide Resistance; Ivermectin; Microbiota; Pesticides; Pyrethrins; RNA, Ribosomal, 16S | 2022 |
Screening of a high-yield strain of avermectin B
Topics: Fermentation; Insecticides; Ivermectin; Mutation | 2023 |
CMC based microcapsules for smart delivery of pesticides with reduced risks to the environment.
Topics: Capsules; Delayed-Action Preparations; Insecticides; Ivermectin; Pesticides | 2023 |
Avermectin induces cardiac toxicity in early embryonic stage of zebrafish.
Topics: Animals; Cardiotoxicity; Embryo, Nonmammalian; Embryonic Development; Ivermectin; Zebrafish; Zebrafish Proteins | 2023 |
Mycelial differentiation linked avermectin production in Streptomyces avermitilis studied with Raman imaging.
Topics: Gene Expression Regulation, Bacterial; Ivermectin; Mycelium; Streptomyces | 2023 |
A new family of glutamate-gated chloride channels in parasitic sea louse Caligus rogercresseyi: A subunit refractory to activation by ivermectin is dominant in heteromeric assemblies.
Topics: Animals; Chloride Channels; Copepoda; Glutamic Acid; Ivermectin; Parasites; Phthiraptera | 2023 |