Page last updated: 2024-08-25

avarol and sesquiterpenes

avarol has been researched along with sesquiterpenes in 57 studies

Research

Studies (57)

Timeframe	Studies, this research(%)	All Research%
pre-1990	18 (31.58)	18.7374
1990's	8 (14.04)	18.2507
2000's	14 (24.56)	29.6817
2010's	14 (24.56)	24.3611
2020's	3 (5.26)	2.80

Authors

Authors	Studies
Belisario, MA; De Rosa, S; Maturo, M; Pecce, R; Villani, GR	1
Bégin, ME; Gasić, M; Klöcking, R; Matthes, E; Müller, WE; Sarma, AS; Schröder, HC	1
Hizi, A; Loya, S	1
Arena, AR; Belisario, MA; De Giulio, A; De Rosa, S; Pecce, R; Strazzullo, G	1
Müller, WE; Schröder, HC	1
Müller, WE; Sarin, PS; Sun, D; Thornton, A	1
Kuchino, Y; Müller, WE; Nishimura, S; Rottmann, M; Schröder, HC	1
Gerner, H; Kuchino, Y; Müller, WE; Reuter, P; Schröder, HC; Sladić, D; Wenger, R	1
Bässler, KH; Dogović, N; Gasić, MJ; Gerner, H; Müller, WE; Schröder, HC; Sladić, D; Zahn, RK	1
Batke, E; Gasić, MJ; Hummel, K; Kallinowski, F; Müller, WE; Ogura, R; Schröder, HC; Vaupel, P	1
Becker, C; Diehl-Seifert, B; Dogović, N; Eich, E; Gasić, MJ; Maidhof, A; Müller, WE; Zahn, RK	1
Bachmann, M; Hess, G; Laubenstein, HP; Meyer zum Büschenfelde, KH; Müller, WE; Reuter, P; Rossol, S; Schröder, HC; Voth, R	1
Maidhof, A; Müller, WE; Renneisen, K; Rottmann, M; Sarin, PS; Schröder, HC; Wenger, R	1
Hess, G; Kuchino, Y; Meyer zum Büschenfelde, KH; Müller, WE; Nishimura, S; Reuter, P; Sarin, PS; Schröder, HC	1
Diehl-Seifert, B; Eich, E; Kljajić, Z; Müller, WE; Sachsse, W; Schröder, HC; Sobel, C; Zahn, RK	1
Diehl-Seifert, B; Maidhof, A; Müller, WE; Schröder, HC; Sobel, C	1
Bechtold, A; Diehl-Seifert, B; Dorn, A; Kljajić, Z; Müller, WE; Sobel, C	1
Bernd, A; Eich, E; Gasić, MJ; Heidemann, D; Kurelec, B; Maidhof, A; Müller, WE; Schröder, HC; Seibert, G; Zahn, RK	1
Dogović, N; Gasić, MJ; Müller, WE; Raether, W; Seibert, G; Zahn, RK	1
Britvić, S; Gasić, MJ; Kurelec, B; Lucić, D; Müller, WE; Zahn, RK	1
Becker, C; Diehl-Seifert, B; Dogovic, N; Gasic, MJ; Maidhof, A; Müller, WE; Sachsse, W; Schröder, HC; Zahn, RK	1
Cariello, L; De Nicola Giudici, M; Zanetti, L	1
Cariello, L; Cuomo, V; Vanzanella, F; Zanetti, L	1
Alcaraz, MJ; Bustos, G; De Rosa, S; Ferrándiz, ML; Payá, M; Sanz, MJ	1
Merker, HJ; Mohamed-Ali, H; Scholz, P	1
Avagnale, G; Belisario, MA; De Caterina, M; De Rosa, S; Maturo, M; Scopacasa, F	1
Batel, R; Böhm, M; De Rosa, S; Müller, IM; Müller, WE; Schröder, HC; Tommonaro, G	1
Kim, SH; Ling, T; Poupon, E; Rueden, EJ; Theodorakis, EA	1
Chakraborty, R; Kuo, YH; Lu, CH; Shen, YC	1
Amigó, M; De Rosa, S; Iodice, C; Mitova, M; Payá, M; Terencio, MC	1
Mendola, D; Osinga, R; Schatton, W; Sipkema, D; Tramper, J; Wijffels, RH	1
Aiello, A; Batel, R; Brümmer, F; de Rosa, S; Fattorusso, E; Menna, M; Müller, WE; Schröder, HC	1
Amigó, M; De Rosa, S; Lamme, E; Olthuis, D; Payá, M; Schalkwijk, J; Terencio, MC	1
Amigó, M; De Rosa, S; Iodice, C; Payá, M; Terencio, MC	1
Immirzi, B; Nicolaus, B; Poli, A; Prisco, RD; Rodríguez, CS; Santillana, M; Tommonaro, G	1
Clare, AS; Gasić, MJ; Hellio, C; Maréchal, JP; Novaković, I; Roussis, V; Sladić, D; Tsoukatou, M; Tufegdzic, S; Vagias, C	1
Gasić, MJ; Sladić, D	1
Abe, H; Ishikawa, M; Kanno, S; Katoh, T; Oguchi, T; Sakurai, J; Watanabe, K	1
Amigó, M; Braza-Boïls, A; De Rosa, S; Payá, M; Terencio, MC	1
De Rosa, S; Iodice, C; Pejin, B; Tommonaro, G	1
de Caralt, S; Sánchez-Fontenla, J; Uriz, MJ; Wijffels, RH	1
Anzelmo, G; Casaburi, A; Nicolaus, B; Pavlova, K; Poli, A; Tommonaro, G	1
Banaigs, B; Bontemps, N; Bry, D; De Caralt, S; Turon, X; Uriz, MJ	1
De Rosa, S; Iodice, C; Pejin, B; Tafuto, A; Tommonaro, G	2
Ciric, A; De Rosa, S; Glamoclija, J; Iodice, C; Nikolic, M; Pejin, B; Sokovic, M; Stanimirovic, B; Tommonaro, G	1
Kodama, R; Namba, T	1
Iodice, C; Jakimov, D; Kojic, V; Lazovic, M; Pejin, B; Tommonaro, G	1
Ciric, A; Markovic, D; Pejin, B; Sokovic, M; Tommonaro, G	1
Abdjul, DB; Kirikoshi, R; Namikoshi, M; Takahashi, O; Ukai, K; Yamazaki, H	1
Cañadas, S; García-Font, N; Iodice, C; Marco-Contelles, J; Oset-Gasque, MJ; Pejin, B; Tommonaro, G; Vitale, RM	1
Glumac, M; Jakimov, D; Kojic, V; Pejin, B; Tommonaro, G	1
Kolarević, S; Kostić, J; Kračun-Kolarević, M; Martinović, R; Milovanović, D; Novaković, I; Sladić, D; Sunjog, K; Vuković-Gačić, B; Đorđević, J	1
Mojović, M; Nakarada, Đ; Pejin, B; Tommonaro, G	1
Kobayashi, K; Namikoshi, M; Ohshiro, T; Suzuki, A; Tomoda, H; Uchida, R; Yamazaki, H	1
Aiello, A; Avunduk, S; Basilico, N; Casertano, M; Fattorusso, C; Gimmelli, R; Guidi, A; Imperatore, C; Luciano, P; Menna, M; Parapini, S; Persico, M; Ruberti, G; Saccoccia, F	1
Filimonov, A; Filimonova, M; Grozdanic, N; Ivanov, S; Kaprin, A; Nikitovic, M; Petovic, S; Shegay, P; Shitova, A; Soldatova, O; Stanojkovic, TP; Vladic, J	1

Reviews

2 review(s) available for avarol and sesquiterpenes

Article	Year
Sustainable production of bioactive compounds from sponges: primmorphs as bioreactors. Progress in molecular and subcellular biology, 2003, Volume: 37 Topics: Amino Acid Sequence; Animals; Bioreactors; Biotechnology; Cell Communication; Cell Line; Cell Proliferation; Culture Media; DNA; Extracellular Matrix; Immunohistochemistry; Iron; Models, Chemical; Molecular Sequence Data; Neurotoxins; Porifera; Quinolinic Acid; Sequence Homology, Amino Acid; Sesquiterpenes; Time Factors; Transfection	2003
Reactivity and biological activity of the marine sesquiterpene hydroquinone avarol and related compounds from sponges of the order Dictyoceratida. Molecules (Basel, Switzerland), 2006, Jan-31, Volume: 11, Issue:1 Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Antiviral Agents; DNA Damage; Golgi Apparatus; Hydroquinones; Models, Biological; Oxidation-Reduction; Porifera; Protein Kinase Inhibitors; Protein Kinases; Protein Processing, Post-Translational; Sesquiterpenes; Tubulin	2006

Article

Year

Sustainable production of bioactive compounds from sponges: primmorphs as bioreactors.

Progress in molecular and subcellular biology, 2003, Volume: 37

Topics: Amino Acid Sequence; Animals; Bioreactors; Biotechnology; Cell Communication; Cell Line; Cell Proliferation; Culture Media; DNA; Extracellular Matrix; Immunohistochemistry; Iron; Models, Chemical; Molecular Sequence Data; Neurotoxins; Porifera; Quinolinic Acid; Sequence Homology, Amino Acid; Sesquiterpenes; Time Factors; Transfection

2003

Reactivity and biological activity of the marine sesquiterpene hydroquinone avarol and related compounds from sponges of the order Dictyoceratida.

Molecules (Basel, Switzerland), 2006, Jan-31, Volume: 11, Issue:1

Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Antiviral Agents; DNA Damage; Golgi Apparatus; Hydroquinones; Models, Biological; Oxidation-Reduction; Porifera; Protein Kinase Inhibitors; Protein Kinases; Protein Processing, Post-Translational; Sesquiterpenes; Tubulin

2006

Other Studies

55 other study(ies) available for avarol and sesquiterpenes

Article	Year
Effect of avarol and avarone on in vitro-induced microsomal lipid peroxidation. Toxicology, 1992, Volume: 72, Issue:2 Topics: Animals; Antineoplastic Agents; Chromatography, High Pressure Liquid; Cyclohexenes; Electron Transport; Lipid Peroxidation; Male; Microsomes, Liver; NADP; Oxidation-Reduction; Rats; Rats, Inbred Strains; Sesquiterpenes	1992
Avarol restores the altered prostaglandin and leukotriene metabolism in monocytes infected with human immunodeficiency virus type 1. Virus research, 1991, Volume: 21, Issue:3 Topics: Antiviral Agents; Arachidonate 5-Lipoxygenase; Cyclooxygenase Inhibitors; Dinoprostone; HIV-1; Leukotriene B4; Lipoxygenase Inhibitors; Monocytes; Prostaglandin-Endoperoxide Synthases; Sesquiterpenes	1991
The inhibition of human immunodeficiency virus type 1 reverse transcriptase by avarol and avarone derivatives. FEBS letters, 1990, Aug-20, Volume: 269, Issue:1 Topics: Animals; Cyclohexenes; Deoxyguanine Nucleotides; Endoribonucleases; HIV-1; Kinetics; Porifera; Reverse Transcriptase Inhibitors; Ribonuclease H; Sesquiterpenes; Structure-Activity Relationship	1990
Effect of avarol, avarone and nine of their natural and synthetic derivatives on microsomal drug-metabolizing enzymes. Toxicology letters, 1991, Volume: 57, Issue:2 Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Antineoplastic Agents; Cyclohexenes; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Male; Methylcholanthrene; Microsomes, Liver; Mutagenicity Tests; Oxidoreductases; Phenobarbital; Rats; Rats, Inbred Strains; Sesquiterpenes	1991
Cell biological aspects of HIV-1 infection: effect of the anti-HIV-1 agent Avarol. International journal of sports medicine, 1991, Volume: 12 Suppl 1 Topics: HIV Infections; HIV-1; Humans; RNA, Transfer; Sesquiterpenes; Transcription, Genetic	1991
Inhibition of replication of the etiologic agent of acquired immune deficiency syndrome (human T-lymphotropic retrovirus/lymphadenopathy-associated virus) by avarol and avarone. Journal of the National Cancer Institute, 1987, Volume: 78, Issue:4 Topics: Acquired Immunodeficiency Syndrome; Cell Line; Cyclohexenes; Cytopathogenic Effect, Viral; HIV; Humans; Reverse Transcriptase Inhibitors; Sesquiterpenes; Virus Replication	1987
Selective inhibition of formation of suppressor glutamine tRNA in Moloney murine leukemia virus-infected NIH-3T3 cells by Avarol. Virology, 1988, Volume: 165, Issue:2 Topics: Animals; Cell Line; DNA-Directed DNA Polymerase; DNA-Directed RNA Polymerases; Gene Expression Regulation; Leukemia, Experimental; Mice; Moloney murine leukemia virus; Peptide Hydrolases; Protein Processing, Post-Translational; RNA-Directed DNA Polymerase; RNA, Messenger; RNA, Transfer, Amino Acid-Specific; RNA, Transfer, Gln; RNA, Viral; Sesquiterpenes; Suppression, Genetic	1988
Suppression of the modulatory effects of the antileukemic and anti-human immunodeficiency virus compound avarol on gene expression by tryptophan. Cancer research, 1989, Apr-15, Volume: 49, Issue:8 Topics: Animals; Antineoplastic Agents; Antiviral Agents; Binding, Competitive; Cell Nucleus; DNA Damage; Gene Expression Regulation; HIV; Interferon-gamma; Mice; RNA, Messenger; Sesquiterpenes; Tryptophan	1989
Avarol-induced DNA strand breakage in vitro and in Friend erythroleukemia cells. Cancer research, 1987, Dec-15, Volume: 47, Issue:24 Pt 1 Topics: Animals; Cell Division; Dimethyl Sulfoxide; DNA; DNA Damage; DNA, Circular; Dose-Response Relationship, Drug; Friend murine leukemia virus; Hydroxides; Hydroxyl Radical; Leukemia, Erythroblastic, Acute; Leukemia, Experimental; Nucleic Acid Conformation; Oxidative Phosphorylation; Oxygen Consumption; Plasmids; Sesquiterpenes; Superoxide Dismutase	1987
Action of the antileukemic and anti-HTLV-III (anti-HIV) agent avarol on the levels of superoxide dismutases and glutathione peroxidase activities in L5178y mouse lymphoma cells. Cell biochemistry and function, 1988, Volume: 6, Issue:2 Topics: Animals; Antiviral Agents; Chromatography, High Pressure Liquid; Electron Spin Resonance Spectroscopy; Glucose; Glutathione Peroxidase; HIV; Hydrogen-Ion Concentration; Leukemia L5178; Leukemia, Experimental; Mice; Oxidation-Reduction; Sesquiterpenes; Superoxide Dismutase; Tumor Cells, Cultured	1988
Avarol, a cytostatically active compound from the marine sponge Dysidea avara. Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1985, Volume: 80, Issue:1 Topics: Animals; Antineoplastic Agents; Autoradiography; Cell Division; Cells, Cultured; DNA, Neoplasm; Lymphoma; Mitosis; Neoplasm Proteins; Porifera; RNA, Neoplasm; Sesquiterpenes; Time Factors	1985
Induction of gamma-interferon by avarol in human peripheral blood lymphocytes. Japanese journal of cancer research : Gann, 1988, Volume: 79, Issue:5 Topics: Gene Expression Regulation; Humans; Interferon-gamma; Kinetics; Lymphocytes; RNA, Messenger; Sesquiterpenes; Transcriptional Activation	1988
Differential modulation of host cell and HIV gene expression by combinations of avarol and AZT in vitro. Biochemical pharmacology, 1988, Oct-15, Volume: 37, Issue:20 Topics: Antiviral Agents; Dose-Response Relationship, Drug; Drug Combinations; Gene Expression Regulation; HIV-1; Humans; RNA, Messenger; Sesquiterpenes; Virus Replication; Zidovudine	1988
Inhibition of expression of natural UAG suppressor glutamine tRNA in HIV-infected human H9 cells in vitro by Avarol. AIDS research and human retroviruses, 1988, Volume: 4, Issue:4 Topics: Animals; Antiviral Agents; Cell Line; Cell Transformation, Viral; Codon; Glutamine; HIV; Humans; Nucleic Acid Hybridization; Protein Biosynthesis; Rabbits; Reticulocytes; RNA, Transfer, Amino Acid-Specific; RNA, Transfer, Gln; RNA, Viral; Sesquiterpenes; Suppression, Genetic; Tobacco Mosaic Virus	1988
Biphasic and differential effects of the cytostatic agents avarone and avarol on DNA metabolism of human and murine T and B lymphocytes. European journal of cancer & clinical oncology, 1986, Volume: 22, Issue:4 Topics: Animals; B-Lymphocytes; Cyclohexenes; DNA; Humans; Lymphocyte Activation; Male; Mice; Mitogens; Mitotic Index; Sesquiterpenes; Spleen; T-Lymphocytes	1986
Influence of the antileukemic and anti-human immunodeficiency virus agent avarol on selected immune responses in vitro and in vivo. Biochemical pharmacology, 1987, May-01, Volume: 36, Issue:9 Topics: Animals; Antibody Formation; Antineoplastic Agents; Antiviral Agents; B-Lymphocytes; Hemolytic Plaque Technique; HIV; Humans; Immunoglobulin G; Immunoglobulin M; Lymphocyte Activation; Mice; Rosette Formation; Sesquiterpenes; Spleen; T-Lymphocytes; Tritium	1987
Sponge secondary metabolites: biochemical and ultrastructural localization of the antimitotic agent avarol in Dysidea avara. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 1986, Volume: 34, Issue:12 Topics: Animals; Chromatography, High Pressure Liquid; Histocytochemistry; Microscopy, Electron; Porifera; Sesquiterpenes	1986
Potent antileukemic activity of the novel cytostatic agent avarone and its analogues in vitro and in vivo. Cancer research, 1985, Volume: 45, Issue:10 Topics: Animals; Antineoplastic Agents; Cell Line; Cyclohexenes; Humans; Lethal Dose 50; Leukemia; Male; Mice; Mutagens; Sesquiterpenes	1985
Antibacterial and antifungal activity of Avarone and Avarol. Zentralblatt fur Bakteriologie, Mikrobiologie, und Hygiene. Series A, Medical microbiology, infectious diseases, virology, parasitology, 1985, Volume: 260, Issue:3 Topics: Bacteria; Cyclohexenes; Dose-Response Relationship, Drug; Fungi; Quinones; Sesquiterpenes	1985
Antimutagenic activity of the novel antileukemic agents, avarone and avarol. Mutation research, 1985, Volume: 144, Issue:2 Topics: Animals; Antineoplastic Agents; Benzopyrene Hydroxylase; Biotransformation; Carps; Cyclohexenes; Microsomes, Liver; Mutagenicity Tests; Mutagens; Salmonella typhimurium; Sesquiterpenes	1985
Inhibition of mitosis by avarol, a natural product isolated from the sponge Dysidea avara. Basic and applied histochemistry, 1985, Volume: 29, Issue:4 Topics: Animals; Cell Division; Chromosomes; Growth Inhibitors; Leukemia L5178; Mice; Microtubule Proteins; Mitosis; Mitotic Index; Porifera; Sesquiterpenes	1985
Developmental aberrations in sea-urchin eggs induced by avarol and two cogeners, the main sesquiterpenoid hydroquinones from the marine sponge, Dysidea avara. Comparative biochemistry and physiology. C: Comparative pharmacology, 1980, Volume: 65C, Issue:1 Topics: Animals; Cell Division; Cell Nucleus; Female; Hydroquinones; Ovum; Porifera; Sea Urchins; Sesquiterpenes	1980
Antimicrobial activity of avarol, a sesquiterpenoid hydroquinone from the marine sponge, Dysidea avara. Comparative biochemistry and physiology. B, Comparative biochemistry, 1982, Volume: 71, Issue:2 Topics: Animals; Antifungal Agents; Enterococcus faecalis; Penicillin G; Porifera; Sesquiterpenes	1982
Avarol and avarone, two new anti-inflammatory agents of marine origin. European journal of pharmacology, 1994, Feb-21, Volume: 253, Issue:1-2 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Carrageenan; Cyclohexenes; Edema; Indomethacin; Inflammation; Leukocytes; Male; Mice; Peritoneum; Phospholipases A; Phospholipases A2; Rats; Sesquiterpenes; Superoxides; Tetradecanoylphorbol Acetate	1994
Inhibition of the effects of rheumatoid synovial fluid cells on chondrogenesis and cartilage breakdown in vitro: possible therapeutical conclusions. A morphological--biochemical study. Virchows Archiv. B, Cell pathology including molecular pathology, 1993, Volume: 64, Issue:1 Topics: Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Cartilage, Articular; Cell Differentiation; Cells, Cultured; Enzyme Activation; Humans; Metalloendopeptidases; Mice; Microscopy, Electron; Plasminogen Activator Inhibitor 2; Prostaglandins; Sesquiterpenes; Synovial Fluid	1993
In vitro effect of avarone and avarol, a quinone/hydroquinone couple of marine origin, on platelet aggregation. Pharmacology & toxicology, 1996, Volume: 79, Issue:6 Topics: Adenosine Diphosphate; Antineoplastic Agents; Arachidonic Acid; Blood Platelets; Cyclohexenes; Humans; Platelet Aggregation Inhibitors; Sesquiterpenes; Thromboxane B2	1996
Application of cell culture for the production of bioactive compounds from sponges: synthesis of avarol by primmorphs from Dysidea avara. Journal of natural products, 2000, Volume: 63, Issue:8 Topics: Animals; Antineoplastic Agents; Antiviral Agents; Cell Aggregation; Cell Culture Techniques; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Croatia; DNA; Electrophoresis, Agar Gel; Porifera; RNA; Sesquiterpenes; Spectrophotometry, Ultraviolet; Thymidine	2000
Unified synthesis of quinone sesquiterpenes based on a radical decarboxylation and quinone addition reaction. Journal of the American Chemical Society, 2002, Oct-16, Volume: 124, Issue:41 Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Antiviral Agents; Cyclohexenes; Quinones; Sesquiterpenes; Substrate Specificity	2002
Isolation of sesquiterpenoids from sponge Dysidea avara and chemical modification of avarol as potential antitumor agents. Natural product research, 2003, Volume: 17, Issue:2 Topics: Acylation; Animals; Antineoplastic Agents; Cyclohexenes; Humans; Inhibitory Concentration 50; KB Cells; Phytotherapy; Porifera; Sesquiterpenes; Tumor Cells, Cultured	2003
Potential antipsoriatic avarol derivatives as antioxidants and inhibitors of PGE(2) generation and proliferation in the HaCaT cell line. Journal of natural products, 2004, Volume: 67, Issue:9 Topics: Antioxidants; Dinoprostone; Free Radical Scavengers; Humans; Inhibitory Concentration 50; Italy; Keratinocytes; L-Lactate Dehydrogenase; Salicylates; Sesquiterpenes; Structure-Activity Relationship	2004
Large-scale production of pharmaceuticals by marine sponges: sea, cell, or synthesis? Biotechnology and bioengineering, 2005, Apr-20, Volume: 90, Issue:2 Topics: Animals; Ethers, Cyclic; Macrolides; Marine Biology; Models, Biological; Models, Economic; Pharmaceutical Preparations; Porifera; Sesquiterpenes	2005
Identification of avarol derivatives as potential antipsoriatic drugs using an in vitro model for keratinocyte growth and differentiation. Life sciences, 2006, Nov-17, Volume: 79, Issue:25 Topics: Animals; Antineoplastic Agents; Cell Differentiation; Cell Proliferation; Cells, Cultured; Cyclooxygenase 2; Drug Evaluation, Preclinical; Dysidea; Elafin; Enzyme-Linked Immunosorbent Assay; Humans; In Vitro Techniques; Interleukin-8; Keratinocytes; Keratins; Membrane Proteins; Psoriasis; RNA, Messenger; Sesquiterpenes; Tumor Necrosis Factor-alpha	2006
Synthesis and evaluation of diverse thio avarol derivatives as potential UVB photoprotective candidates. Bioorganic & medicinal chemistry letters, 2007, May-01, Volume: 17, Issue:9 Topics: Antioxidants; Cell Line, Tumor; Chemistry, Pharmaceutical; Drug Design; Humans; Magnetic Resonance Spectroscopy; Models, Chemical; Molecular Conformation; Neutrophils; NF-kappa B; Photochemistry; Reactive Oxygen Species; Sesquiterpenes; Tumor Necrosis Factor-alpha; Ultraviolet Rays	2007
Chemical composition and biotechnological properties of a polysaccharide from the peels and antioxidative content from the pulp of Passiflora liguralis fruits. Journal of agricultural and food chemistry, 2007, Sep-05, Volume: 55, Issue:18 Topics: Antioxidants; Biotechnology; Chemical Phenomena; Chemistry, Physical; Food Packaging; Fruit; Glucans; Passiflora; Polysaccharides; Sesquiterpenes; Xylans	2007
Evaluation of the activity of the sponge metabolites avarol and avarone and their synthetic derivatives against fouling micro- and macroorganisms. Molecules (Basel, Switzerland), 2007, May-15, Volume: 12, Issue:5 Topics: Animals; Anti-Bacterial Agents; Antifungal Agents; Drug Evaluation, Preclinical; Microbial Sensitivity Tests; Porifera; Sesquiterpenes	2007
Highly efficient total synthesis of the marine natural products (+)-avarone, (+)-avarol, (-)-neoavarone, (-)-neoavarol and (+)-aureol. Chemistry (Weinheim an der Bergstrasse, Germany), 2008, Volume: 14, Issue:3 Topics: Biological Factors; Cyclohexenes; Molecular Conformation; Sesquiterpenes; Stereoisomerism	2008
Avarol inhibits TNF-alpha generation and NF-kappaB activation in human cells and in animal models. Life sciences, 2008, Jan-30, Volume: 82, Issue:5-6 Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Cell Line; Disease Models, Animal; Dose-Response Relationship, Drug; Epidermis; Female; Humans; Hyperplasia; Inflammation; Inflammation Mediators; Keratinocytes; Mice; Monocytes; NF-kappa B p50 Subunit; Peroxidase; Psoriasis; Sesquiterpenes; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha	2008
Synthesis and biological activities of thio-avarol derivatives. Journal of natural products, 2008, Volume: 71, Issue:11 Topics: Animals; Anti-Infective Agents; Artemia; Cholinesterase Inhibitors; Dysidea; Free Radical Scavengers; Microbial Sensitivity Tests; Sesquiterpenes; Structure-Activity Relationship; Sulfur Compounds	2008
In situ aquaculture methods for Dysidea avara (Demospongiae, Porifera) in the northwestern Mediterranean. Marine drugs, 2010, May-26, Volume: 8, Issue:6 Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Antiviral Agents; Aquaculture; Dysidea; Mediterranean Sea; Photobacterium; Sesquiterpenes; Spain; Survival Analysis; Tissue Extracts	2010
Production and chemical characterization of an exopolysaccharide synthesized by psychrophilic yeast strain Sporobolomyces salmonicolor AL₁ isolated from Livingston Island, Antarctica. Folia microbiologica, 2010, Volume: 55, Issue:6 Topics: Animals; Antarctic Regions; Basidiomycota; Cell Survival; Culture Media; Macrophages; Mannans; Mice; Molecular Weight; Polysaccharides; Sesquiterpenes	2010
Sources of secondary metabolite variation in Dysidea avara (Porifera: Demospongiae): the importance of having good neighbors. Marine drugs, 2013, Feb-18, Volume: 11, Issue:2 Topics: Animals; beta-Thalassemia; Ecosystem; Molecular Structure; Porifera; Sesquiterpenes; Temperature; Time Factors	2013
Further in vitro biological activity evaluation of amino-, thio- and ester-derivatives of avarol. Journal of enzyme inhibition and medicinal chemistry, 2015, Volume: 30, Issue:2 Topics: Acetylcholinesterase; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Cholinesterase Inhibitors; Humans; Molecular Structure; Sesquiterpenes; Structure-Activity Relationship	2015
Further in vitro evaluation of antimicrobial activity of the marine sesquiterpene hydroquinone avarol. Current pharmaceutical biotechnology, 2014, Volume: 15, Issue:6 Topics: Anti-Bacterial Agents; Antifungal Agents; Biofilms; Fungi; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Pyocyanine; Quorum Sensing; Sesquiterpenes	2014
Avarol induces apoptosis in pancreatic ductal adenocarcinoma cells by activating PERK-eIF2α-CHOP signaling. Marine drugs, 2015, Apr-16, Volume: 13, Issue:4 Topics: Animals; Antineoplastic Agents; Apoptosis; Biomarkers; Carcinoma, Pancreatic Ductal; Cell Line; Cell Line, Tumor; Dysidea; eIF-2 Kinase; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Eukaryotic Initiation Factor-2; Gene Expression Regulation, Neoplastic; Heat-Shock Proteins; Humans; Inhibitory Concentration 50; Neoplasm Proteins; Pancreatic Neoplasms; RNA Interference; Sesquiterpenes; Signal Transduction; Transcription Factor CHOP; Up-Regulation	2015
Further in vitro biological activity evaluation of amino-, thio- and ester-derivatives of avarol. Journal of enzyme inhibition and medicinal chemistry, 2016, Volume: 31, Issue:4 Topics: Acetylcholinesterase; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Molecular Conformation; Sesquiterpenes; Structure-Activity Relationship	2016
In vitro evaluation of cytotoxic and mutagenic activity of avarol. Natural product research, 2016, Volume: 30, Issue:11 Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; DNA Fragmentation; HT29 Cells; Humans; Mutagens; Porifera; Sesquiterpenes	2016
In vitro avarol does affect the growth of Candida sp. Natural product research, 2016, Volume: 30, Issue:17 Topics: Animals; Candida; Cholinesterase Inhibitors; Microbial Sensitivity Tests; Porifera; Sesquiterpenes	2016
Sesquiterpene Hydroquinones with Protein Tyrosine Phosphatase 1B Inhibitory Activities from a Dysidea sp. Marine Sponge Collected in Okinawa. Journal of natural products, 2016, 07-22, Volume: 79, Issue:7 Topics: Animals; Dysidea; Hydroquinones; Inhibitory Concentration 50; Molecular Structure; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Sesquiterpenes; Structure-Activity Relationship	2016
Avarol derivatives as competitive AChE inhibitors, non hepatotoxic and neuroprotective agents for Alzheimer's disease. European journal of medicinal chemistry, 2016, Oct-21, Volume: 122 Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Butyrylcholinesterase; Cholinesterase Inhibitors; Electrophorus; Hep G2 Cells; Humans; Liver; Molecular Docking Simulation; Neuroprotective Agents; Protein Conformation; Sesquiterpenes	2016
The redox couple avarol/avarone in the fight with malignant gliomas: the case study of U-251 MG cells. Natural product research, 2018, Volume: 32, Issue:5 Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Line, Tumor; Comet Assay; Cyclohexenes; Dacarbazine; DNA Damage; Doxorubicin; Fibroblasts; Glioma; Humans; Oxidation-Reduction; Sesquiterpenes; Temozolomide	2018
Evaluation of genotoxic potential of avarol, avarone, and its methoxy and methylamino derivatives in prokaryotic and eukaryotic test models. Drug and chemical toxicology, 2019, Volume: 42, Issue:2 Topics: A549 Cells; Cell Line, Tumor; Comet Assay; Cyclohexenes; DNA Damage; Humans; Male; Mutagens; Salmonella typhimurium; Sesquiterpenes; Toxicity Tests	2019
Liposomal integration method for assessing antioxidative activity of water insoluble compounds towards biologically relevant free radicals: example of avarol. Journal of liposome research, 2020, Volume: 30, Issue:3 Topics: Animals; Antioxidants; Dysidea; Free Radicals; Liposomes; Molecular Structure; Sesquiterpenes; Solubility; Water	2020
Inhibition of neutral lipid synthesis by avarols from a marine sponge. Bioorganic & medicinal chemistry letters, 2019, 08-15, Volume: 29, Issue:16 Topics: Animals; CHO Cells; Cricetulus; Dose-Response Relationship, Drug; Lipid Droplets; Lipids; Molecular Structure; Particle Size; Porifera; Sesquiterpenes; Structure-Activity Relationship; Surface Properties	2019
Investigating the Antiparasitic Potential of the Marine Sesquiterpene Avarone, Its Reduced form Avarol, and the Novel Semisynthetic Thiazinoquinone Analogue Thiazoavarone. Marine drugs, 2020, Feb-14, Volume: 18, Issue:2 Topics: Animals; Antiparasitic Agents; Cyclohexenes; Dysidea; Leishmania; Leishmania infantum; Leishmania tropica; Plasmodium falciparum; Quinones; Schistosoma mansoni; Sesquiterpenes; Thiazines	2020
Evaluation of In Vitro Cytotoxic Potential of Avarol towards Human Cancer Cell Lines and In Vivo Antitumor Activity in Solid Tumor Models. Molecules (Basel, Switzerland), 2022, Dec-19, Volume: 27, Issue:24 Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Line; Colonic Neoplasms; Humans; Hydroquinones; Lung Neoplasms; Mice; Sesquiterpenes	2022